Amino acid dipepetide frequency for Tortoise microvirus 41

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.42AlaAla: 5.42 ± 1.884
1.084AlaCys: 1.084 ± 0.765
3.794AlaAsp: 3.794 ± 1.445
5.42AlaGlu: 5.42 ± 1.885
2.71AlaPhe: 2.71 ± 1.159
5.962AlaGly: 5.962 ± 3.22
0.542AlaHis: 0.542 ± 0.464
1.626AlaIle: 1.626 ± 1.006
3.252AlaLys: 3.252 ± 1.243
5.962AlaLeu: 5.962 ± 1.15
2.168AlaMet: 2.168 ± 1.125
5.42AlaAsn: 5.42 ± 1.229
4.878AlaPro: 4.878 ± 1.931
5.42AlaGln: 5.42 ± 1.674
2.168AlaArg: 2.168 ± 0.822
7.046AlaSer: 7.046 ± 1.699
4.878AlaThr: 4.878 ± 1.021
6.504AlaVal: 6.504 ± 1.564
0.0AlaTrp: 0.0 ± 0.0
2.71AlaTyr: 2.71 ± 0.755
0.0AlaXaa: 0.0 ± 0.0
Cys
0.542CysAla: 0.542 ± 0.612
0.0CysCys: 0.0 ± 0.0
0.542CysAsp: 0.542 ± 0.411
0.542CysGlu: 0.542 ± 0.579
0.0CysPhe: 0.0 ± 0.0
1.084CysGly: 1.084 ± 0.481
1.084CysHis: 1.084 ± 0.765
0.0CysIle: 0.0 ± 0.0
0.542CysLys: 0.542 ± 0.612
2.168CysLeu: 2.168 ± 1.209
0.0CysMet: 0.0 ± 0.0
1.084CysAsn: 1.084 ± 0.758
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
2.71CysArg: 2.71 ± 1.3
0.0CysSer: 0.0 ± 0.0
1.626CysThr: 1.626 ± 1.209
1.084CysVal: 1.084 ± 0.685
0.0CysTrp: 0.0 ± 0.0
1.084CysTyr: 1.084 ± 1.157
0.0CysXaa: 0.0 ± 0.0
Asp
6.504AspAla: 6.504 ± 3.119
1.084AspCys: 1.084 ± 0.661
4.878AspAsp: 4.878 ± 1.836
0.542AspGlu: 0.542 ± 0.411
5.962AspPhe: 5.962 ± 1.791
3.794AspGly: 3.794 ± 1.293
0.542AspHis: 0.542 ± 0.411
4.336AspIle: 4.336 ± 0.914
3.252AspLys: 3.252 ± 0.973
5.962AspLeu: 5.962 ± 1.743
1.626AspMet: 1.626 ± 0.874
1.084AspAsn: 1.084 ± 0.661
1.084AspPro: 1.084 ± 0.897
1.084AspGln: 1.084 ± 0.928
3.252AspArg: 3.252 ± 1.04
3.252AspSer: 3.252 ± 1.696
4.336AspThr: 4.336 ± 1.094
3.794AspVal: 3.794 ± 1.488
0.542AspTrp: 0.542 ± 0.463
5.42AspTyr: 5.42 ± 1.07
0.0AspXaa: 0.0 ± 0.0
Glu
2.71GluAla: 2.71 ± 1.345
0.0GluCys: 0.0 ± 0.0
0.542GluAsp: 0.542 ± 0.464
1.626GluGlu: 1.626 ± 0.787
2.168GluPhe: 2.168 ± 0.554
1.084GluGly: 1.084 ± 0.925
1.084GluHis: 1.084 ± 0.617
2.168GluIle: 2.168 ± 1.054
3.252GluLys: 3.252 ± 0.831
4.336GluLeu: 4.336 ± 1.735
2.168GluMet: 2.168 ± 0.516
1.626GluAsn: 1.626 ± 0.963
1.626GluPro: 1.626 ± 0.856
3.794GluGln: 3.794 ± 1.622
4.336GluArg: 4.336 ± 2.097
4.336GluSer: 4.336 ± 1.629
1.084GluThr: 1.084 ± 0.624
4.878GluVal: 4.878 ± 1.698
0.542GluTrp: 0.542 ± 0.463
2.71GluTyr: 2.71 ± 1.335
0.0GluXaa: 0.0 ± 0.0
Phe
3.252PheAla: 3.252 ± 1.382
1.084PheCys: 1.084 ± 0.925
3.252PheAsp: 3.252 ± 1.388
3.794PheGlu: 3.794 ± 1.242
2.168PhePhe: 2.168 ± 1.247
2.71PheGly: 2.71 ± 0.924
0.0PheHis: 0.0 ± 0.0
4.336PheIle: 4.336 ± 1.368
2.168PheLys: 2.168 ± 1.45
3.252PheLeu: 3.252 ± 1.373
1.626PheMet: 1.626 ± 0.874
3.252PheAsn: 3.252 ± 0.6
2.168PhePro: 2.168 ± 1.125
2.71PheGln: 2.71 ± 1.671
1.626PheArg: 1.626 ± 1.015
2.71PheSer: 2.71 ± 0.846
4.336PheThr: 4.336 ± 1.214
0.0PheVal: 0.0 ± 0.0
0.542PheTrp: 0.542 ± 0.464
1.084PheTyr: 1.084 ± 0.624
0.0PheXaa: 0.0 ± 0.0
Gly
2.168GlyAla: 2.168 ± 1.192
1.084GlyCys: 1.084 ± 0.661
4.878GlyAsp: 4.878 ± 1.28
2.168GlyGlu: 2.168 ± 0.73
3.252GlyPhe: 3.252 ± 1.188
2.168GlyGly: 2.168 ± 0.73
1.084GlyHis: 1.084 ± 0.422
3.252GlyIle: 3.252 ± 0.958
1.084GlyLys: 1.084 ± 0.617
8.672GlyLeu: 8.672 ± 1.596
1.626GlyMet: 1.626 ± 0.647
3.794GlyAsn: 3.794 ± 1.863
0.0GlyPro: 0.0 ± 0.0
1.084GlyGln: 1.084 ± 0.928
2.71GlyArg: 2.71 ± 0.746
8.13GlySer: 8.13 ± 2.437
2.168GlyThr: 2.168 ± 1.13
4.878GlyVal: 4.878 ± 1.463
0.542GlyTrp: 0.542 ± 0.463
4.336GlyTyr: 4.336 ± 1.075
0.0GlyXaa: 0.0 ± 0.0
His
1.626HisAla: 1.626 ± 0.827
0.0HisCys: 0.0 ± 0.0
0.542HisAsp: 0.542 ± 0.612
0.0HisGlu: 0.0 ± 0.0
1.084HisPhe: 1.084 ± 0.928
1.626HisGly: 1.626 ± 0.632
0.0HisHis: 0.0 ± 0.0
0.542HisIle: 0.542 ± 0.659
0.542HisLys: 0.542 ± 0.463
1.626HisLeu: 1.626 ± 0.915
0.0HisMet: 0.0 ± 0.0
1.084HisAsn: 1.084 ± 0.596
1.084HisPro: 1.084 ± 0.821
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
1.626HisSer: 1.626 ± 0.961
2.71HisThr: 2.71 ± 0.971
1.626HisVal: 1.626 ± 0.602
0.0HisTrp: 0.0 ± 0.0
1.084HisTyr: 1.084 ± 0.481
0.0HisXaa: 0.0 ± 0.0
Ile
5.42IleAla: 5.42 ± 1.336
0.542IleCys: 0.542 ± 0.463
4.336IleAsp: 4.336 ± 2.496
2.168IleGlu: 2.168 ± 1.484
1.084IlePhe: 1.084 ± 0.879
3.252IleGly: 3.252 ± 1.489
0.542IleHis: 0.542 ± 0.463
0.542IleIle: 0.542 ± 0.715
1.626IleLys: 1.626 ± 1.255
3.252IleLeu: 3.252 ± 1.501
0.542IleMet: 0.542 ± 0.411
2.168IleAsn: 2.168 ± 0.844
5.962IlePro: 5.962 ± 1.461
1.626IleGln: 1.626 ± 0.889
2.168IleArg: 2.168 ± 0.807
4.878IleSer: 4.878 ± 2.02
1.626IleThr: 1.626 ± 1.232
1.626IleVal: 1.626 ± 0.765
0.542IleTrp: 0.542 ± 0.411
1.626IleTyr: 1.626 ± 0.905
0.0IleXaa: 0.0 ± 0.0
Lys
2.71LysAla: 2.71 ± 1.466
0.0LysCys: 0.0 ± 0.0
1.084LysAsp: 1.084 ± 0.897
2.71LysGlu: 2.71 ± 0.946
1.084LysPhe: 1.084 ± 0.879
1.626LysGly: 1.626 ± 0.705
0.0LysHis: 0.0 ± 0.0
1.626LysIle: 1.626 ± 0.686
0.542LysLys: 0.542 ± 0.659
4.336LysLeu: 4.336 ± 1.223
2.168LysMet: 2.168 ± 0.886
3.252LysAsn: 3.252 ± 0.856
0.542LysPro: 0.542 ± 0.715
2.168LysGln: 2.168 ± 1.096
2.168LysArg: 2.168 ± 1.45
3.252LysSer: 3.252 ± 1.574
3.794LysThr: 3.794 ± 1.676
1.084LysVal: 1.084 ± 0.596
0.0LysTrp: 0.0 ± 0.0
2.71LysTyr: 2.71 ± 2.313
0.0LysXaa: 0.0 ± 0.0
Leu
7.046LeuAla: 7.046 ± 1.144
1.626LeuCys: 1.626 ± 0.986
5.962LeuAsp: 5.962 ± 2.099
3.794LeuGlu: 3.794 ± 1.293
4.336LeuPhe: 4.336 ± 1.606
11.382LeuGly: 11.382 ± 2.229
1.084LeuHis: 1.084 ± 0.481
1.626LeuIle: 1.626 ± 0.705
2.71LeuLys: 2.71 ± 1.27
6.504LeuLeu: 6.504 ± 3.286
0.542LeuMet: 0.542 ± 0.612
4.878LeuAsn: 4.878 ± 1.392
8.672LeuPro: 8.672 ± 2.748
3.794LeuGln: 3.794 ± 0.805
4.336LeuArg: 4.336 ± 0.786
10.84LeuSer: 10.84 ± 1.299
6.504LeuThr: 6.504 ± 2.057
2.168LeuVal: 2.168 ± 1.478
1.626LeuTrp: 1.626 ± 1.232
3.252LeuTyr: 3.252 ± 1.289
0.0LeuXaa: 0.0 ± 0.0
Met
4.336MetAla: 4.336 ± 1.252
0.0MetCys: 0.0 ± 0.0
1.084MetAsp: 1.084 ± 0.617
0.0MetGlu: 0.0 ± 0.0
0.542MetPhe: 0.542 ± 0.463
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.542MetIle: 0.542 ± 0.411
2.168MetLys: 2.168 ± 1.39
1.626MetLeu: 1.626 ± 0.606
0.542MetMet: 0.542 ± 0.411
0.0MetAsn: 0.0 ± 0.0
2.168MetPro: 2.168 ± 0.593
1.084MetGln: 1.084 ± 0.928
1.084MetArg: 1.084 ± 0.422
4.336MetSer: 4.336 ± 1.43
1.626MetThr: 1.626 ± 0.606
0.542MetVal: 0.542 ± 0.464
0.0MetTrp: 0.0 ± 0.0
3.252MetTyr: 3.252 ± 1.231
0.0MetXaa: 0.0 ± 0.0
Asn
4.336AsnAla: 4.336 ± 1.794
0.0AsnCys: 0.0 ± 0.0
2.168AsnAsp: 2.168 ± 1.056
4.336AsnGlu: 4.336 ± 1.3
3.794AsnPhe: 3.794 ± 0.967
2.71AsnGly: 2.71 ± 1.185
0.542AsnHis: 0.542 ± 0.411
1.626AsnIle: 1.626 ± 0.679
2.168AsnLys: 2.168 ± 0.961
3.794AsnLeu: 3.794 ± 0.94
1.084AsnMet: 1.084 ± 0.596
2.168AsnAsn: 2.168 ± 1.105
3.252AsnPro: 3.252 ± 1.449
1.626AsnGln: 1.626 ± 0.787
3.252AsnArg: 3.252 ± 0.648
2.71AsnSer: 2.71 ± 1.044
3.252AsnThr: 3.252 ± 1.144
3.252AsnVal: 3.252 ± 1.676
1.084AsnTrp: 1.084 ± 0.748
3.252AsnTyr: 3.252 ± 0.709
0.0AsnXaa: 0.0 ± 0.0
Pro
2.168ProAla: 2.168 ± 0.561
1.626ProCys: 1.626 ± 1.18
3.794ProAsp: 3.794 ± 0.752
3.252ProGlu: 3.252 ± 1.644
1.084ProPhe: 1.084 ± 0.481
1.084ProGly: 1.084 ± 0.481
1.626ProHis: 1.626 ± 1.122
4.878ProIle: 4.878 ± 2.224
1.626ProLys: 1.626 ± 0.923
3.794ProLeu: 3.794 ± 1.066
2.71ProMet: 2.71 ± 0.846
2.71ProAsn: 2.71 ± 1.154
1.626ProPro: 1.626 ± 1.054
2.168ProGln: 2.168 ± 1.056
2.71ProArg: 2.71 ± 1.286
10.298ProSer: 10.298 ± 1.623
4.336ProThr: 4.336 ± 0.942
5.962ProVal: 5.962 ± 3.699
0.0ProTrp: 0.0 ± 0.0
2.71ProTyr: 2.71 ± 2.053
0.0ProXaa: 0.0 ± 0.0
Gln
3.252GlnAla: 3.252 ± 1.668
0.542GlnCys: 0.542 ± 0.463
3.794GlnAsp: 3.794 ± 0.998
1.626GlnGlu: 1.626 ± 0.963
2.71GlnPhe: 2.71 ± 1.671
1.626GlnGly: 1.626 ± 0.408
1.626GlnHis: 1.626 ± 1.062
1.626GlnIle: 1.626 ± 0.632
1.084GlnLys: 1.084 ± 0.928
3.252GlnLeu: 3.252 ± 2.324
0.542GlnMet: 0.542 ± 0.463
4.878GlnAsn: 4.878 ± 1.873
0.542GlnPro: 0.542 ± 0.411
5.962GlnGln: 5.962 ± 4.553
3.794GlnArg: 3.794 ± 1.279
2.71GlnSer: 2.71 ± 1.069
3.252GlnThr: 3.252 ± 1.223
2.168GlnVal: 2.168 ± 0.922
0.542GlnTrp: 0.542 ± 0.464
1.626GlnTyr: 1.626 ± 0.99
0.0GlnXaa: 0.0 ± 0.0
Arg
3.252ArgAla: 3.252 ± 1.744
0.542ArgCys: 0.542 ± 0.411
3.794ArgAsp: 3.794 ± 0.853
2.71ArgGlu: 2.71 ± 0.761
0.542ArgPhe: 0.542 ± 0.464
3.794ArgGly: 3.794 ± 0.715
0.542ArgHis: 0.542 ± 0.464
2.71ArgIle: 2.71 ± 1.362
2.168ArgLys: 2.168 ± 1.152
6.504ArgLeu: 6.504 ± 1.388
1.084ArgMet: 1.084 ± 0.422
2.168ArgAsn: 2.168 ± 0.863
4.878ArgPro: 4.878 ± 2.04
3.794ArgGln: 3.794 ± 1.659
3.252ArgArg: 3.252 ± 0.923
3.252ArgSer: 3.252 ± 1.064
2.71ArgThr: 2.71 ± 1.231
3.252ArgVal: 3.252 ± 1.222
0.0ArgTrp: 0.0 ± 0.0
4.336ArgTyr: 4.336 ± 1.282
0.0ArgXaa: 0.0 ± 0.0
Ser
5.962SerAla: 5.962 ± 1.699
1.084SerCys: 1.084 ± 0.925
4.878SerAsp: 4.878 ± 1.983
3.794SerGlu: 3.794 ± 1.361
3.252SerPhe: 3.252 ± 1.104
5.962SerGly: 5.962 ± 1.712
2.71SerHis: 2.71 ± 0.807
3.794SerIle: 3.794 ± 1.607
3.252SerLys: 3.252 ± 1.599
10.298SerLeu: 10.298 ± 1.84
1.084SerMet: 1.084 ± 1.034
1.626SerAsn: 1.626 ± 0.691
7.588SerPro: 7.588 ± 1.588
3.252SerGln: 3.252 ± 1.158
3.794SerArg: 3.794 ± 1.097
8.13SerSer: 8.13 ± 2.302
4.336SerThr: 4.336 ± 1.679
7.046SerVal: 7.046 ± 2.057
0.0SerTrp: 0.0 ± 0.0
4.336SerTyr: 4.336 ± 1.581
0.0SerXaa: 0.0 ± 0.0
Thr
7.588ThrAla: 7.588 ± 1.332
0.0ThrCys: 0.0 ± 0.0
3.794ThrAsp: 3.794 ± 0.906
3.794ThrGlu: 3.794 ± 1.095
5.42ThrPhe: 5.42 ± 1.76
2.168ThrGly: 2.168 ± 1.056
0.0ThrHis: 0.0 ± 0.0
3.252ThrIle: 3.252 ± 0.858
2.71ThrLys: 2.71 ± 0.807
5.962ThrLeu: 5.962 ± 2.237
1.626ThrMet: 1.626 ± 0.606
1.626ThrAsn: 1.626 ± 0.647
4.878ThrPro: 4.878 ± 2.021
2.71ThrGln: 2.71 ± 1.044
3.252ThrArg: 3.252 ± 0.71
2.168ThrSer: 2.168 ± 0.749
3.252ThrThr: 3.252 ± 1.438
4.336ThrVal: 4.336 ± 0.739
0.0ThrTrp: 0.0 ± 0.0
3.794ThrTyr: 3.794 ± 1.206
0.0ThrXaa: 0.0 ± 0.0
Val
3.794ValAla: 3.794 ± 0.945
2.168ValCys: 2.168 ± 1.536
5.42ValAsp: 5.42 ± 1.309
2.168ValGlu: 2.168 ± 1.209
1.626ValPhe: 1.626 ± 0.752
3.794ValGly: 3.794 ± 1.63
1.084ValHis: 1.084 ± 0.661
4.336ValIle: 4.336 ± 1.124
1.626ValLys: 1.626 ± 1.02
7.588ValLeu: 7.588 ± 1.102
1.626ValMet: 1.626 ± 1.217
3.252ValAsn: 3.252 ± 0.725
6.504ValPro: 6.504 ± 2.01
1.084ValGln: 1.084 ± 0.752
4.336ValArg: 4.336 ± 2.01
2.71ValSer: 2.71 ± 0.949
2.71ValThr: 2.71 ± 1.176
2.71ValVal: 2.71 ± 1.044
0.0ValTrp: 0.0 ± 0.0
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.542TrpAla: 0.542 ± 0.464
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.542TrpHis: 0.542 ± 0.411
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.542TrpLeu: 0.542 ± 0.463
0.0TrpMet: 0.0 ± 0.0
0.542TrpAsn: 0.542 ± 0.464
0.0TrpPro: 0.0 ± 0.0
0.542TrpGln: 0.542 ± 0.464
1.084TrpArg: 1.084 ± 0.617
1.084TrpSer: 1.084 ± 0.925
1.626TrpThr: 1.626 ± 0.765
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.336TyrAla: 4.336 ± 1.757
1.626TyrCys: 1.626 ± 0.765
3.794TyrAsp: 3.794 ± 1.661
1.626TyrGlu: 1.626 ± 0.408
3.252TyrPhe: 3.252 ± 1.16
3.252TyrGly: 3.252 ± 1.261
2.168TyrHis: 2.168 ± 1.079
2.71TyrIle: 2.71 ± 1.518
1.084TyrLys: 1.084 ± 0.596
3.252TyrLeu: 3.252 ± 1.171
1.626TyrMet: 1.626 ± 0.745
3.794TyrAsn: 3.794 ± 0.873
2.71TyrPro: 2.71 ± 1.135
3.252TyrGln: 3.252 ± 0.709
3.252TyrArg: 3.252 ± 1.489
2.71TyrSer: 2.71 ± 1.518
2.168TyrThr: 2.168 ± 1.056
2.168TyrVal: 2.168 ± 0.873
0.542TyrTrp: 0.542 ± 0.463
2.71TyrTyr: 2.71 ± 1.044
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (1846 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski