Amino acid dipepetide frequency for Flavihumibacter soli

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.141AlaAla: 6.141 ± 0.099	0.652AlaCys: 0.652 ± 0.024	4.355AlaAsp: 4.355 ± 0.057	4.773AlaGlu: 4.773 ± 0.07	3.504AlaPhe: 3.504 ± 0.058	6.247AlaGly: 6.247 ± 0.096	1.145AlaHis: 1.145 ± 0.028	5.267AlaIle: 5.267 ± 0.074	4.087AlaLys: 4.087 ± 0.063	6.919AlaLeu: 6.919 ± 0.08	1.637AlaMet: 1.637 ± 0.041	3.446AlaAsn: 3.446 ± 0.061	2.3AlaPro: 2.3 ± 0.047	2.528AlaGln: 2.528 ± 0.044	2.904AlaArg: 2.904 ± 0.05	4.783AlaSer: 4.783 ± 0.067	3.713AlaThr: 3.713 ± 0.072	4.927AlaVal: 4.927 ± 0.066	0.769AlaTrp: 0.769 ± 0.027	2.716AlaTyr: 2.716 ± 0.052	0.0AlaXaa: 0.0 ± 0.0
Cys	0.493CysAla: 0.493 ± 0.023	0.106CysCys: 0.106 ± 0.009	0.397CysAsp: 0.397 ± 0.016	0.383CysGlu: 0.383 ± 0.017	0.407CysPhe: 0.407 ± 0.018	0.62CysGly: 0.62 ± 0.025	0.184CysHis: 0.184 ± 0.014	0.587CysIle: 0.587 ± 0.022	0.424CysLys: 0.424 ± 0.02	0.774CysLeu: 0.774 ± 0.025	0.168CysMet: 0.168 ± 0.011	0.347CysAsn: 0.347 ± 0.018	0.292CysPro: 0.292 ± 0.017	0.224CysGln: 0.224 ± 0.014	0.337CysArg: 0.337 ± 0.017	0.583CysSer: 0.583 ± 0.024	0.392CysThr: 0.392 ± 0.02	0.421CysVal: 0.421 ± 0.02	0.077CysTrp: 0.077 ± 0.008	0.299CysTyr: 0.299 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	3.721AspAla: 3.721 ± 0.069	0.374AspCys: 0.374 ± 0.016	2.587AspAsp: 2.587 ± 0.053	3.543AspGlu: 3.543 ± 0.063	3.134AspPhe: 3.134 ± 0.055	3.632AspGly: 3.632 ± 0.065	1.051AspHis: 1.051 ± 0.03	4.124AspIle: 4.124 ± 0.058	3.757AspLys: 3.757 ± 0.056	5.413AspLeu: 5.413 ± 0.073	1.157AspMet: 1.157 ± 0.027	2.596AspAsn: 2.596 ± 0.052	2.412AspPro: 2.412 ± 0.042	1.933AspGln: 1.933 ± 0.041	2.365AspArg: 2.365 ± 0.042	3.287AspSer: 3.287 ± 0.055	2.489AspThr: 2.489 ± 0.035	3.254AspVal: 3.254 ± 0.044	0.751AspTrp: 0.751 ± 0.027	2.352AspTyr: 2.352 ± 0.047	0.0AspXaa: 0.0 ± 0.0
Glu	4.374GluAla: 4.374 ± 0.073	0.344GluCys: 0.344 ± 0.017	2.942GluAsp: 2.942 ± 0.049	4.085GluGlu: 4.085 ± 0.078	2.76GluPhe: 2.76 ± 0.042	3.684GluGly: 3.684 ± 0.061	1.183GluHis: 1.183 ± 0.027	4.747GluIle: 4.747 ± 0.069	4.803GluLys: 4.803 ± 0.071	6.165GluLeu: 6.165 ± 0.095	1.558GluMet: 1.558 ± 0.035	3.384GluAsn: 3.384 ± 0.06	1.83GluPro: 1.83 ± 0.041	2.372GluGln: 2.372 ± 0.05	2.82GluArg: 2.82 ± 0.052	3.324GluSer: 3.324 ± 0.057	3.247GluThr: 3.247 ± 0.05	3.99GluVal: 3.99 ± 0.054	0.663GluTrp: 0.663 ± 0.025	2.216GluTyr: 2.216 ± 0.04	0.0GluXaa: 0.0 ± 0.0
Phe	3.352PheAla: 3.352 ± 0.059	0.438PheCys: 0.438 ± 0.018	2.919PheAsp: 2.919 ± 0.05	2.848PheGlu: 2.848 ± 0.053	2.406PhePhe: 2.406 ± 0.049	3.522PheGly: 3.522 ± 0.058	0.877PheHis: 0.877 ± 0.03	3.652PheIle: 3.652 ± 0.053	3.147PheLys: 3.147 ± 0.051	4.599PheLeu: 4.599 ± 0.072	1.027PheMet: 1.027 ± 0.026	2.997PheAsn: 2.997 ± 0.051	1.828PhePro: 1.828 ± 0.039	1.489PheGln: 1.489 ± 0.035	2.19PheArg: 2.19 ± 0.038	3.915PheSer: 3.915 ± 0.066	3.103PheThr: 3.103 ± 0.052	2.754PheVal: 2.754 ± 0.045	0.597PheTrp: 0.597 ± 0.024	1.98PheTyr: 1.98 ± 0.038	0.0PheXaa: 0.0 ± 0.0
Gly	4.662GlyAla: 4.662 ± 0.076	0.63GlyCys: 0.63 ± 0.028	3.516GlyAsp: 3.516 ± 0.059	3.619GlyGlu: 3.619 ± 0.053	3.801GlyPhe: 3.801 ± 0.061	5.014GlyGly: 5.014 ± 0.085	1.202GlyHis: 1.202 ± 0.031	5.491GlyIle: 5.491 ± 0.072	5.198GlyLys: 5.198 ± 0.07	6.516GlyLeu: 6.516 ± 0.082	1.773GlyMet: 1.773 ± 0.041	3.675GlyAsn: 3.675 ± 0.076	1.732GlyPro: 1.732 ± 0.047	2.321GlyGln: 2.321 ± 0.045	2.948GlyArg: 2.948 ± 0.052	4.951GlySer: 4.951 ± 0.077	4.391GlyThr: 4.391 ± 0.071	4.321GlyVal: 4.321 ± 0.065	0.916GlyTrp: 0.916 ± 0.028	2.938GlyTyr: 2.938 ± 0.046	0.0GlyXaa: 0.0 ± 0.0
His	1.169HisAla: 1.169 ± 0.035	0.185HisCys: 0.185 ± 0.012	0.907HisAsp: 0.907 ± 0.027	1.037HisGlu: 1.037 ± 0.03	1.096HisPhe: 1.096 ± 0.03	1.211HisGly: 1.211 ± 0.028	0.506HisHis: 0.506 ± 0.021	1.37HisIle: 1.37 ± 0.036	0.941HisLys: 0.941 ± 0.028	1.887HisLeu: 1.887 ± 0.044	0.371HisMet: 0.371 ± 0.017	0.848HisAsn: 0.848 ± 0.022	1.007HisPro: 1.007 ± 0.031	0.711HisGln: 0.711 ± 0.027	0.841HisArg: 0.841 ± 0.026	1.177HisSer: 1.177 ± 0.03	0.956HisThr: 0.956 ± 0.031	0.944HisVal: 0.944 ± 0.026	0.233HisTrp: 0.233 ± 0.015	0.793HisTyr: 0.793 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	5.539IleAla: 5.539 ± 0.076	0.71IleCys: 0.71 ± 0.02	4.069IleAsp: 4.069 ± 0.059	4.264IleGlu: 4.264 ± 0.063	3.269IlePhe: 3.269 ± 0.053	4.849IleGly: 4.849 ± 0.08	1.305IleHis: 1.305 ± 0.031	5.301IleIle: 5.301 ± 0.085	4.468IleLys: 4.468 ± 0.064	6.8IleLeu: 6.8 ± 0.091	1.425IleMet: 1.425 ± 0.034	4.102IleAsn: 4.102 ± 0.059	3.185IlePro: 3.185 ± 0.052	2.231IleGln: 2.231 ± 0.045	3.599IleArg: 3.599 ± 0.061	5.731IleSer: 5.731 ± 0.072	4.47IleThr: 4.47 ± 0.069	4.306IleVal: 4.306 ± 0.064	0.715IleTrp: 0.715 ± 0.024	2.547IleTyr: 2.547 ± 0.046	0.0IleXaa: 0.0 ± 0.0
Lys	4.975LysAla: 4.975 ± 0.065	0.277LysCys: 0.277 ± 0.015	3.812LysAsp: 3.812 ± 0.059	4.599LysGlu: 4.599 ± 0.072	2.639LysPhe: 2.639 ± 0.048	4.349LysGly: 4.349 ± 0.077	1.173LysHis: 1.173 ± 0.033	4.741LysIle: 4.741 ± 0.071	4.778LysLys: 4.778 ± 0.073	5.902LysLeu: 5.902 ± 0.068	1.706LysMet: 1.706 ± 0.037	3.782LysAsn: 3.782 ± 0.064	2.763LysPro: 2.763 ± 0.05	2.45LysGln: 2.45 ± 0.05	2.831LysArg: 2.831 ± 0.046	4.003LysSer: 4.003 ± 0.062	3.829LysThr: 3.829 ± 0.06	4.27LysVal: 4.27 ± 0.065	0.717LysTrp: 0.717 ± 0.023	2.565LysTyr: 2.565 ± 0.043	0.0LysXaa: 0.0 ± 0.0
Leu	7.041LeuAla: 7.041 ± 0.085	0.724LeuCys: 0.724 ± 0.026	4.771LeuAsp: 4.771 ± 0.071	5.382LeuGlu: 5.382 ± 0.081	4.636LeuPhe: 4.636 ± 0.067	5.902LeuGly: 5.902 ± 0.079	1.681LeuHis: 1.681 ± 0.036	7.036LeuIle: 7.036 ± 0.095	7.057LeuLys: 7.057 ± 0.077	9.413LeuLeu: 9.413 ± 0.099	2.159LeuMet: 2.159 ± 0.045	5.673LeuAsn: 5.673 ± 0.078	4.163LeuPro: 4.163 ± 0.061	3.524LeuGln: 3.524 ± 0.056	4.157LeuArg: 4.157 ± 0.065	7.331LeuSer: 7.331 ± 0.088	5.54LeuThr: 5.54 ± 0.074	5.765LeuVal: 5.765 ± 0.069	0.895LeuTrp: 0.895 ± 0.03	3.173LeuTyr: 3.173 ± 0.049	0.0LeuXaa: 0.0 ± 0.0
Met	1.783MetAla: 1.783 ± 0.036	0.131MetCys: 0.131 ± 0.01	1.17MetAsp: 1.17 ± 0.03	1.419MetGlu: 1.419 ± 0.04	0.823MetPhe: 0.823 ± 0.024	1.527MetGly: 1.527 ± 0.039	0.425MetHis: 0.425 ± 0.019	1.633MetIle: 1.633 ± 0.037	1.949MetLys: 1.949 ± 0.045	2.177MetLeu: 2.177 ± 0.04	0.575MetMet: 0.575 ± 0.023	1.301MetAsn: 1.301 ± 0.033	1.044MetPro: 1.044 ± 0.027	0.875MetGln: 0.875 ± 0.026	0.969MetArg: 0.969 ± 0.027	1.361MetSer: 1.361 ± 0.032	1.174MetThr: 1.174 ± 0.029	1.398MetVal: 1.398 ± 0.035	0.181MetTrp: 0.181 ± 0.011	0.594MetTyr: 0.594 ± 0.022	0.0MetXaa: 0.0 ± 0.0
Asn	3.661AsnAla: 3.661 ± 0.055	0.382AsnCys: 0.382 ± 0.017	2.84AsnAsp: 2.84 ± 0.056	3.005AsnGlu: 3.005 ± 0.05	2.75AsnPhe: 2.75 ± 0.057	3.812AsnGly: 3.812 ± 0.065	0.943AsnHis: 0.943 ± 0.029	3.938AsnIle: 3.938 ± 0.057	3.261AsnLys: 3.261 ± 0.057	5.131AsnLeu: 5.131 ± 0.076	1.187AsnMet: 1.187 ± 0.03	2.976AsnAsn: 2.976 ± 0.062	2.727AsnPro: 2.727 ± 0.058	1.897AsnGln: 1.897 ± 0.039	2.434AsnArg: 2.434 ± 0.047	3.654AsnSer: 3.654 ± 0.062	3.028AsnThr: 3.028 ± 0.057	3.156AsnVal: 3.156 ± 0.051	0.708AsnTrp: 0.708 ± 0.027	2.408AsnTyr: 2.408 ± 0.051	0.0AsnXaa: 0.0 ± 0.0
Pro	3.492ProAla: 3.492 ± 0.064	0.237ProCys: 0.237 ± 0.018	2.687ProAsp: 2.687 ± 0.047	3.261ProGlu: 3.261 ± 0.05	1.941ProPhe: 1.941 ± 0.044	3.193ProGly: 3.193 ± 0.053	0.737ProHis: 0.737 ± 0.025	2.156ProIle: 2.156 ± 0.048	1.983ProLys: 1.983 ± 0.043	3.528ProLeu: 3.528 ± 0.056	0.751ProMet: 0.751 ± 0.027	1.77ProAsn: 1.77 ± 0.039	1.165ProPro: 1.165 ± 0.035	1.398ProGln: 1.398 ± 0.035	1.258ProArg: 1.258 ± 0.036	2.325ProSer: 2.325 ± 0.041	1.72ProThr: 1.72 ± 0.04	3.613ProVal: 3.613 ± 0.057	0.426ProTrp: 0.426 ± 0.02	1.517ProTyr: 1.517 ± 0.039	0.0ProXaa: 0.0 ± 0.0
Gln	2.645GlnAla: 2.645 ± 0.046	0.183GlnCys: 0.183 ± 0.013	1.676GlnAsp: 1.676 ± 0.034	2.018GlnGlu: 2.018 ± 0.045	1.619GlnPhe: 1.619 ± 0.04	2.084GlnGly: 2.084 ± 0.046	0.685GlnHis: 0.685 ± 0.021	2.414GlnIle: 2.414 ± 0.046	2.492GlnLys: 2.492 ± 0.045	3.59GlnLeu: 3.59 ± 0.048	0.878GlnMet: 0.878 ± 0.026	1.918GlnAsn: 1.918 ± 0.046	1.45GlnPro: 1.45 ± 0.035	1.674GlnGln: 1.674 ± 0.04	1.501GlnArg: 1.501 ± 0.034	2.209GlnSer: 2.209 ± 0.042	2.06GlnThr: 2.06 ± 0.042	2.454GlnVal: 2.454 ± 0.052	0.407GlnTrp: 0.407 ± 0.018	1.313GlnTyr: 1.313 ± 0.031	0.0GlnXaa: 0.0 ± 0.0
Arg	2.598ArgAla: 2.598 ± 0.048	0.246ArgCys: 0.246 ± 0.015	2.216ArgAsp: 2.216 ± 0.04	2.84ArgGlu: 2.84 ± 0.051	2.389ArgPhe: 2.389 ± 0.045	2.422ArgGly: 2.422 ± 0.043	0.81ArgHis: 0.81 ± 0.026	3.47ArgIle: 3.47 ± 0.044	3.135ArgLys: 3.135 ± 0.055	4.32ArgLeu: 4.32 ± 0.06	1.158ArgMet: 1.158 ± 0.03	2.51ArgAsn: 2.51 ± 0.049	1.556ArgPro: 1.556 ± 0.034	1.705ArgGln: 1.705 ± 0.038	1.911ArgArg: 1.911 ± 0.045	2.916ArgSer: 2.916 ± 0.049	2.271ArgThr: 2.271 ± 0.043	2.759ArgVal: 2.759 ± 0.049	0.552ArgTrp: 0.552 ± 0.022	1.859ArgTyr: 1.859 ± 0.041	0.0ArgXaa: 0.0 ± 0.0
Ser	5.007SerAla: 5.007 ± 0.072	0.545SerCys: 0.545 ± 0.026	3.661SerAsp: 3.661 ± 0.056	3.853SerGlu: 3.853 ± 0.062	3.751SerPhe: 3.751 ± 0.06	5.511SerGly: 5.511 ± 0.076	1.174SerHis: 1.174 ± 0.029	4.837SerIle: 4.837 ± 0.068	4.205SerLys: 4.205 ± 0.066	6.652SerLeu: 6.652 ± 0.076	1.425SerMet: 1.425 ± 0.033	3.35SerAsn: 3.35 ± 0.058	2.688SerPro: 2.688 ± 0.049	2.209SerGln: 2.209 ± 0.045	3.103SerArg: 3.103 ± 0.052	4.849SerSer: 4.849 ± 0.078	3.564SerThr: 3.564 ± 0.068	4.677SerVal: 4.677 ± 0.06	0.827SerTrp: 0.827 ± 0.029	2.782SerTyr: 2.782 ± 0.054	0.0SerXaa: 0.0 ± 0.0
Thr	4.492ThrAla: 4.492 ± 0.083	0.359ThrCys: 0.359 ± 0.018	3.303ThrAsp: 3.303 ± 0.057	3.256ThrGlu: 3.256 ± 0.052	2.768ThrPhe: 2.768 ± 0.055	4.832ThrGly: 4.832 ± 0.08	0.965ThrHis: 0.965 ± 0.029	3.965ThrIle: 3.965 ± 0.058	2.707ThrLys: 2.707 ± 0.05	5.266ThrLeu: 5.266 ± 0.08	0.975ThrMet: 0.975 ± 0.029	2.612ThrAsn: 2.612 ± 0.052	2.497ThrPro: 2.497 ± 0.051	1.681ThrGln: 1.681 ± 0.035	2.238ThrArg: 2.238 ± 0.044	3.695ThrSer: 3.695 ± 0.068	3.056ThrThr: 3.056 ± 0.068	3.983ThrVal: 3.983 ± 0.066	0.666ThrTrp: 0.666 ± 0.025	2.214ThrTyr: 2.214 ± 0.049	0.0ThrXaa: 0.0 ± 0.0
Val	4.469ValAla: 4.469 ± 0.065	0.558ValCys: 0.558 ± 0.023	3.381ValAsp: 3.381 ± 0.059	3.594ValGlu: 3.594 ± 0.059	3.239ValPhe: 3.239 ± 0.052	3.713ValGly: 3.713 ± 0.068	1.062ValHis: 1.062 ± 0.031	4.995ValIle: 4.995 ± 0.07	4.494ValLys: 4.494 ± 0.063	6.077ValLeu: 6.077 ± 0.065	1.535ValMet: 1.535 ± 0.036	3.689ValAsn: 3.689 ± 0.058	2.503ValPro: 2.503 ± 0.046	2.001ValGln: 2.001 ± 0.04	2.692ValArg: 2.692 ± 0.045	4.933ValSer: 4.933 ± 0.066	3.746ValThr: 3.746 ± 0.073	4.12ValVal: 4.12 ± 0.066	0.682ValTrp: 0.682 ± 0.025	2.385ValTyr: 2.385 ± 0.04	0.0ValXaa: 0.0 ± 0.0
Trp	0.746TrpAla: 0.746 ± 0.025	0.093TrpCys: 0.093 ± 0.009	0.635TrpAsp: 0.635 ± 0.026	0.681TrpGlu: 0.681 ± 0.021	0.57TrpPhe: 0.57 ± 0.022	0.812TrpGly: 0.812 ± 0.031	0.272TrpHis: 0.272 ± 0.017	0.781TrpIle: 0.781 ± 0.025	0.829TrpLys: 0.829 ± 0.025	1.176TrpLeu: 1.176 ± 0.034	0.317TrpMet: 0.317 ± 0.016	0.688TrpAsn: 0.688 ± 0.023	0.323TrpPro: 0.323 ± 0.018	0.464TrpGln: 0.464 ± 0.019	0.516TrpArg: 0.516 ± 0.021	0.676TrpSer: 0.676 ± 0.026	0.594TrpThr: 0.594 ± 0.023	0.681TrpVal: 0.681 ± 0.023	0.203TrpTrp: 0.203 ± 0.015	0.405TrpTyr: 0.405 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.454TyrAla: 2.454 ± 0.046	0.34TyrCys: 0.34 ± 0.016	2.089TyrAsp: 2.089 ± 0.042	2.033TyrGlu: 2.033 ± 0.037	2.141TyrPhe: 2.141 ± 0.044	2.677TyrGly: 2.677 ± 0.05	0.809TyrHis: 0.809 ± 0.027	2.38TyrIle: 2.38 ± 0.042	2.444TyrLys: 2.444 ± 0.047	3.719TyrLeu: 3.719 ± 0.062	0.728TyrMet: 0.728 ± 0.026	2.232TyrAsn: 2.232 ± 0.051	1.691TyrPro: 1.691 ± 0.033	1.583TyrGln: 1.583 ± 0.04	2.03TyrArg: 2.03 ± 0.045	2.969TyrSer: 2.969 ± 0.051	2.188TyrThr: 2.188 ± 0.051	2.076TyrVal: 2.076 ± 0.043	0.475TyrTrp: 0.475 ± 0.018	1.663TyrTyr: 1.663 ± 0.049	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3820 proteins (1307137 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---