Amino acid dipepetide frequency for Allokutzneria albata

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
18.968AlaAla: 18.968 ± 0.124
1.105AlaCys: 1.105 ± 0.023
7.848AlaAsp: 7.848 ± 0.051
9.651AlaGlu: 9.651 ± 0.081
3.518AlaPhe: 3.518 ± 0.038
11.674AlaGly: 11.674 ± 0.076
2.629AlaHis: 2.629 ± 0.035
4.01AlaIle: 4.01 ± 0.042
3.236AlaLys: 3.236 ± 0.049
14.479AlaLeu: 14.479 ± 0.107
2.54AlaMet: 2.54 ± 0.038
2.342AlaAsn: 2.342 ± 0.04
6.126AlaPro: 6.126 ± 0.06
3.621AlaGln: 3.621 ± 0.046
9.432AlaArg: 9.432 ± 0.075
5.84AlaSer: 5.84 ± 0.056
6.729AlaThr: 6.729 ± 0.054
12.27AlaVal: 12.27 ± 0.083
1.864AlaTrp: 1.864 ± 0.026
2.233AlaTyr: 2.233 ± 0.035
0.0AlaXaa: 0.0 ± 0.0
Cys
1.145CysAla: 1.145 ± 0.024
0.126CysCys: 0.126 ± 0.008
0.505CysAsp: 0.505 ± 0.015
0.454CysGlu: 0.454 ± 0.015
0.25CysPhe: 0.25 ± 0.009
1.008CysGly: 1.008 ± 0.024
0.197CysHis: 0.197 ± 0.008
0.157CysIle: 0.157 ± 0.009
0.142CysLys: 0.142 ± 0.007
0.762CysLeu: 0.762 ± 0.022
0.158CysMet: 0.158 ± 0.008
0.145CysAsn: 0.145 ± 0.009
0.519CysPro: 0.519 ± 0.016
0.199CysGln: 0.199 ± 0.01
0.666CysArg: 0.666 ± 0.017
0.552CysSer: 0.552 ± 0.016
0.501CysThr: 0.501 ± 0.015
0.763CysVal: 0.763 ± 0.02
0.146CysTrp: 0.146 ± 0.007
0.189CysTyr: 0.189 ± 0.008
0.0CysXaa: 0.0 ± 0.0
Asp
7.182AspAla: 7.182 ± 0.069
0.437AspCys: 0.437 ± 0.015
3.271AspAsp: 3.271 ± 0.044
3.816AspGlu: 3.816 ± 0.046
1.622AspPhe: 1.622 ± 0.028
5.812AspGly: 5.812 ± 0.06
1.386AspHis: 1.386 ± 0.025
1.792AspIle: 1.792 ± 0.028
1.184AspLys: 1.184 ± 0.024
6.366AspLeu: 6.366 ± 0.058
0.798AspMet: 0.798 ± 0.019
1.086AspAsn: 1.086 ± 0.025
4.26AspPro: 4.26 ± 0.044
1.615AspGln: 1.615 ± 0.024
4.875AspArg: 4.875 ± 0.045
2.665AspSer: 2.665 ± 0.031
2.707AspThr: 2.707 ± 0.037
5.183AspVal: 5.183 ± 0.056
1.014AspTrp: 1.014 ± 0.02
1.237AspTyr: 1.237 ± 0.024
0.0AspXaa: 0.0 ± 0.0
Glu
6.797GluAla: 6.797 ± 0.065
0.411GluCys: 0.411 ± 0.013
2.827GluAsp: 2.827 ± 0.04
3.136GluGlu: 3.136 ± 0.042
1.868GluPhe: 1.868 ± 0.026
3.705GluGly: 3.705 ± 0.04
1.847GluHis: 1.847 ± 0.029
2.468GluIle: 2.468 ± 0.031
1.3GluLys: 1.3 ± 0.022
7.973GluLeu: 7.973 ± 0.076
0.908GluMet: 0.908 ± 0.023
1.106GluAsn: 1.106 ± 0.023
3.559GluPro: 3.559 ± 0.036
2.512GluGln: 2.512 ± 0.034
5.647GluArg: 5.647 ± 0.055
2.482GluSer: 2.482 ± 0.042
2.644GluThr: 2.644 ± 0.039
5.162GluVal: 5.162 ± 0.051
0.876GluTrp: 0.876 ± 0.022
0.997GluTyr: 0.997 ± 0.022
0.0GluXaa: 0.0 ± 0.0
Phe
4.006PheAla: 4.006 ± 0.04
0.282PheCys: 0.282 ± 0.012
2.193PheAsp: 2.193 ± 0.032
1.475PheGlu: 1.475 ± 0.027
0.905PhePhe: 0.905 ± 0.022
3.275PheGly: 3.275 ± 0.045
0.645PheHis: 0.645 ± 0.017
0.667PheIle: 0.667 ± 0.013
0.448PheLys: 0.448 ± 0.015
2.722PheLeu: 2.722 ± 0.035
0.393PheMet: 0.393 ± 0.014
0.576PheAsn: 0.576 ± 0.016
1.453PhePro: 1.453 ± 0.025
0.693PheGln: 0.693 ± 0.017
1.92PheArg: 1.92 ± 0.029
1.638PheSer: 1.638 ± 0.025
2.075PheThr: 2.075 ± 0.028
2.565PheVal: 2.565 ± 0.034
0.438PheTrp: 0.438 ± 0.014
0.572PheTyr: 0.572 ± 0.015
0.0PheXaa: 0.0 ± 0.0
Gly
9.969GlyAla: 9.969 ± 0.065
0.878GlyCys: 0.878 ± 0.021
4.789GlyAsp: 4.789 ± 0.048
5.126GlyGlu: 5.126 ± 0.044
3.023GlyPhe: 3.023 ± 0.041
7.925GlyGly: 7.925 ± 0.086
2.056GlyHis: 2.056 ± 0.027
3.46GlyIle: 3.46 ± 0.036
2.651GlyLys: 2.651 ± 0.041
9.286GlyLeu: 9.286 ± 0.073
2.153GlyMet: 2.153 ± 0.028
1.895GlyAsn: 1.895 ± 0.031
4.454GlyPro: 4.454 ± 0.047
2.676GlyGln: 2.676 ± 0.038
6.921GlyArg: 6.921 ± 0.056
5.124GlySer: 5.124 ± 0.051
5.616GlyThr: 5.616 ± 0.052
8.216GlyVal: 8.216 ± 0.065
1.717GlyTrp: 1.717 ± 0.026
2.217GlyTyr: 2.217 ± 0.033
0.0GlyXaa: 0.0 ± 0.0
His
2.632HisAla: 2.632 ± 0.034
0.256HisCys: 0.256 ± 0.011
1.241HisAsp: 1.241 ± 0.022
1.23HisGlu: 1.23 ± 0.019
0.627HisPhe: 0.627 ± 0.015
2.225HisGly: 2.225 ± 0.031
0.669HisHis: 0.669 ± 0.019
0.648HisIle: 0.648 ± 0.017
0.346HisLys: 0.346 ± 0.011
2.318HisLeu: 2.318 ± 0.032
0.323HisMet: 0.323 ± 0.012
0.464HisAsn: 0.464 ± 0.014
1.644HisPro: 1.644 ± 0.028
0.638HisGln: 0.638 ± 0.017
2.098HisArg: 2.098 ± 0.031
1.163HisSer: 1.163 ± 0.023
1.103HisThr: 1.103 ± 0.021
1.906HisVal: 1.906 ± 0.033
0.38HisTrp: 0.38 ± 0.012
0.503HisTyr: 0.503 ± 0.014
0.0HisXaa: 0.0 ± 0.0
Ile
5.395IleAla: 5.395 ± 0.049
0.297IleCys: 0.297 ± 0.011
2.426IleAsp: 2.426 ± 0.035
2.106IleGlu: 2.106 ± 0.032
0.709IlePhe: 0.709 ± 0.018
3.843IleGly: 3.843 ± 0.042
0.556IleHis: 0.556 ± 0.015
0.913IleIle: 0.913 ± 0.021
0.752IleLys: 0.752 ± 0.018
2.097IleLeu: 2.097 ± 0.034
0.45IleMet: 0.45 ± 0.014
0.775IleAsn: 0.775 ± 0.019
1.841IlePro: 1.841 ± 0.03
0.663IleGln: 0.663 ± 0.016
2.234IleArg: 2.234 ± 0.027
2.037IleSer: 2.037 ± 0.03
2.589IleThr: 2.589 ± 0.031
2.821IleVal: 2.821 ± 0.033
0.379IleTrp: 0.379 ± 0.012
0.595IleTyr: 0.595 ± 0.017
0.0IleXaa: 0.0 ± 0.0
Lys
2.8LysAla: 2.8 ± 0.041
0.146LysCys: 0.146 ± 0.008
1.205LysAsp: 1.205 ± 0.024
1.039LysGlu: 1.039 ± 0.021
0.492LysPhe: 0.492 ± 0.015
1.664LysGly: 1.664 ± 0.032
0.534LysHis: 0.534 ± 0.016
0.959LysIle: 0.959 ± 0.02
0.633LysLys: 0.633 ± 0.019
2.429LysLeu: 2.429 ± 0.038
0.363LysMet: 0.363 ± 0.011
0.465LysAsn: 0.465 ± 0.014
1.549LysPro: 1.549 ± 0.031
0.777LysGln: 0.777 ± 0.019
1.694LysArg: 1.694 ± 0.029
1.08LysSer: 1.08 ± 0.023
1.223LysThr: 1.223 ± 0.024
2.042LysVal: 2.042 ± 0.037
0.315LysTrp: 0.315 ± 0.013
0.416LysTyr: 0.416 ± 0.015
0.0LysXaa: 0.0 ± 0.0
Leu
15.528LeuAla: 15.528 ± 0.094
0.897LeuCys: 0.897 ± 0.021
6.934LeuAsp: 6.934 ± 0.062
4.683LeuGlu: 4.683 ± 0.051
2.873LeuPhe: 2.873 ± 0.048
9.705LeuGly: 9.705 ± 0.074
2.322LeuHis: 2.322 ± 0.032
3.355LeuIle: 3.355 ± 0.039
1.737LeuLys: 1.737 ± 0.03
11.465LeuLeu: 11.465 ± 0.097
1.595LeuMet: 1.595 ± 0.026
1.83LeuAsn: 1.83 ± 0.029
6.61LeuPro: 6.61 ± 0.053
1.943LeuGln: 1.943 ± 0.03
9.53LeuArg: 9.53 ± 0.078
6.029LeuSer: 6.029 ± 0.053
6.587LeuThr: 6.587 ± 0.053
10.264LeuVal: 10.264 ± 0.078
1.381LeuTrp: 1.381 ± 0.024
1.615LeuTyr: 1.615 ± 0.032
0.0LeuXaa: 0.0 ± 0.0
Met
2.171MetAla: 2.171 ± 0.031
0.172MetCys: 0.172 ± 0.009
0.856MetAsp: 0.856 ± 0.021
0.68MetGlu: 0.68 ± 0.016
0.484MetPhe: 0.484 ± 0.014
1.245MetGly: 1.245 ± 0.025
0.353MetHis: 0.353 ± 0.012
0.805MetIle: 0.805 ± 0.017
0.406MetLys: 0.406 ± 0.013
1.88MetLeu: 1.88 ± 0.028
0.276MetMet: 0.276 ± 0.011
0.418MetAsn: 0.418 ± 0.013
1.109MetPro: 1.109 ± 0.022
0.399MetGln: 0.399 ± 0.013
1.65MetArg: 1.65 ± 0.025
1.381MetSer: 1.381 ± 0.02
1.5MetThr: 1.5 ± 0.027
1.457MetVal: 1.457 ± 0.027
0.231MetTrp: 0.231 ± 0.008
0.276MetTyr: 0.276 ± 0.012
0.0MetXaa: 0.0 ± 0.0
Asn
2.46AsnAla: 2.46 ± 0.036
0.19AsnCys: 0.19 ± 0.01
1.018AsnAsp: 1.018 ± 0.023
0.926AsnGlu: 0.926 ± 0.02
0.506AsnPhe: 0.506 ± 0.017
2.127AsnGly: 2.127 ± 0.038
0.409AsnHis: 0.409 ± 0.013
0.614AsnIle: 0.614 ± 0.018
0.445AsnLys: 0.445 ± 0.015
1.865AsnLeu: 1.865 ± 0.029
0.275AsnMet: 0.275 ± 0.011
0.461AsnAsn: 0.461 ± 0.016
1.529AsnPro: 1.529 ± 0.03
0.591AsnGln: 0.591 ± 0.017
1.482AsnArg: 1.482 ± 0.022
1.009AsnSer: 1.009 ± 0.021
1.183AsnThr: 1.183 ± 0.026
1.453AsnVal: 1.453 ± 0.032
0.319AsnTrp: 0.319 ± 0.013
0.446AsnTyr: 0.446 ± 0.013
0.0AsnXaa: 0.0 ± 0.0
Pro
7.52ProAla: 7.52 ± 0.068
0.384ProCys: 0.384 ± 0.013
4.091ProAsp: 4.091 ± 0.041
4.347ProGlu: 4.347 ± 0.046
1.619ProPhe: 1.619 ± 0.028
6.131ProGly: 6.131 ± 0.055
1.221ProHis: 1.221 ± 0.022
1.659ProIle: 1.659 ± 0.029
1.414ProLys: 1.414 ± 0.024
5.277ProLeu: 5.277 ± 0.052
1.052ProMet: 1.052 ± 0.019
1.144ProAsn: 1.144 ± 0.022
3.37ProPro: 3.37 ± 0.064
1.613ProGln: 1.613 ± 0.03
3.798ProArg: 3.798 ± 0.044
3.1ProSer: 3.1 ± 0.035
3.171ProThr: 3.171 ± 0.04
5.576ProVal: 5.576 ± 0.049
0.907ProTrp: 0.907 ± 0.02
1.017ProTyr: 1.017 ± 0.02
0.0ProXaa: 0.0 ± 0.0
Gln
3.513GlnAla: 3.513 ± 0.046
0.192GlnCys: 0.192 ± 0.008
1.306GlnAsp: 1.306 ± 0.023
1.342GlnGlu: 1.342 ± 0.025
0.725GlnPhe: 0.725 ± 0.017
2.007GlnGly: 2.007 ± 0.033
0.694GlnHis: 0.694 ± 0.017
1.037GlnIle: 1.037 ± 0.02
0.546GlnLys: 0.546 ± 0.013
3.219GlnLeu: 3.219 ± 0.047
0.433GlnMet: 0.433 ± 0.014
0.531GlnAsn: 0.531 ± 0.015
1.829GlnPro: 1.829 ± 0.032
1.24GlnGln: 1.24 ± 0.032
2.847GlnArg: 2.847 ± 0.037
1.163GlnSer: 1.163 ± 0.023
1.191GlnThr: 1.191 ± 0.024
2.57GlnVal: 2.57 ± 0.035
0.491GlnTrp: 0.491 ± 0.014
0.544GlnTyr: 0.544 ± 0.015
0.0GlnXaa: 0.0 ± 0.0
Arg
9.832ArgAla: 9.832 ± 0.073
0.7ArgCys: 0.7 ± 0.018
4.107ArgAsp: 4.107 ± 0.041
4.952ArgGlu: 4.952 ± 0.047
2.598ArgPhe: 2.598 ± 0.031
5.799ArgGly: 5.799 ± 0.051
1.872ArgHis: 1.872 ± 0.027
3.217ArgIle: 3.217 ± 0.036
1.84ArgLys: 1.84 ± 0.033
8.891ArgLeu: 8.891 ± 0.085
1.971ArgMet: 1.971 ± 0.028
1.548ArgAsn: 1.548 ± 0.025
4.536ArgPro: 4.536 ± 0.046
2.342ArgGln: 2.342 ± 0.034
7.402ArgArg: 7.402 ± 0.074
4.331ArgSer: 4.331 ± 0.036
4.819ArgThr: 4.819 ± 0.05
6.55ArgVal: 6.55 ± 0.057
1.442ArgTrp: 1.442 ± 0.024
1.81ArgTyr: 1.81 ± 0.031
0.0ArgXaa: 0.0 ± 0.0
Ser
6.891SerAla: 6.891 ± 0.055
0.5SerCys: 0.5 ± 0.015
2.66SerAsp: 2.66 ± 0.032
2.628SerGlu: 2.628 ± 0.033
1.659SerPhe: 1.659 ± 0.029
6.022SerGly: 6.022 ± 0.057
0.978SerHis: 0.978 ± 0.02
1.615SerIle: 1.615 ± 0.026
1.089SerLys: 1.089 ± 0.022
5.083SerLeu: 5.083 ± 0.054
1.151SerMet: 1.151 ± 0.023
0.925SerAsn: 0.925 ± 0.022
3.088SerPro: 3.088 ± 0.036
1.251SerGln: 1.251 ± 0.023
3.796SerArg: 3.796 ± 0.035
3.118SerSer: 3.118 ± 0.039
3.495SerThr: 3.495 ± 0.038
4.605SerVal: 4.605 ± 0.042
1.027SerTrp: 1.027 ± 0.023
1.183SerTyr: 1.183 ± 0.021
0.0SerXaa: 0.0 ± 0.0
Thr
7.947ThrAla: 7.947 ± 0.057
0.472ThrCys: 0.472 ± 0.017
3.22ThrAsp: 3.22 ± 0.043
3.495ThrGlu: 3.495 ± 0.045
1.582ThrPhe: 1.582 ± 0.028
6.041ThrGly: 6.041 ± 0.057
1.109ThrHis: 1.109 ± 0.023
1.868ThrIle: 1.868 ± 0.024
1.309ThrLys: 1.309 ± 0.025
5.329ThrLeu: 5.329 ± 0.051
1.041ThrMet: 1.041 ± 0.019
1.076ThrAsn: 1.076 ± 0.023
3.715ThrPro: 3.715 ± 0.042
1.266ThrGln: 1.266 ± 0.025
3.74ThrArg: 3.74 ± 0.041
3.224ThrSer: 3.224 ± 0.042
3.89ThrThr: 3.89 ± 0.068
5.977ThrVal: 5.977 ± 0.05
0.945ThrTrp: 0.945 ± 0.022
1.191ThrTyr: 1.191 ± 0.026
0.0ThrXaa: 0.0 ± 0.0
Val
11.371ValAla: 11.371 ± 0.077
0.783ValCys: 0.783 ± 0.017
5.825ValAsp: 5.825 ± 0.055
5.379ValGlu: 5.379 ± 0.049
2.688ValPhe: 2.688 ± 0.036
7.008ValGly: 7.008 ± 0.058
2.112ValHis: 2.112 ± 0.034
3.242ValIle: 3.242 ± 0.039
1.668ValLys: 1.668 ± 0.031
11.363ValLeu: 11.363 ± 0.086
1.341ValMet: 1.341 ± 0.026
1.755ValAsn: 1.755 ± 0.03
5.243ValPro: 5.243 ± 0.053
2.186ValGln: 2.186 ± 0.031
7.478ValArg: 7.478 ± 0.063
4.754ValSer: 4.754 ± 0.045
5.345ValThr: 5.345 ± 0.048
9.301ValVal: 9.301 ± 0.078
1.139ValTrp: 1.139 ± 0.023
1.445ValTyr: 1.445 ± 0.023
0.0ValXaa: 0.0 ± 0.0
Trp
1.681TrpAla: 1.681 ± 0.031
0.18TrpCys: 0.18 ± 0.008
0.758TrpAsp: 0.758 ± 0.019
0.754TrpGlu: 0.754 ± 0.017
0.552TrpPhe: 0.552 ± 0.017
1.068TrpGly: 1.068 ± 0.022
0.388TrpHis: 0.388 ± 0.012
0.572TrpIle: 0.572 ± 0.017
0.348TrpLys: 0.348 ± 0.012
1.925TrpLeu: 1.925 ± 0.032
0.309TrpMet: 0.309 ± 0.011
0.375TrpAsn: 0.375 ± 0.014
0.889TrpPro: 0.889 ± 0.021
0.622TrpGln: 0.622 ± 0.016
1.46TrpArg: 1.46 ± 0.028
1.022TrpSer: 1.022 ± 0.019
1.035TrpThr: 1.035 ± 0.02
1.135TrpVal: 1.135 ± 0.023
0.368TrpTrp: 0.368 ± 0.014
0.31TrpTyr: 0.31 ± 0.011
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.308TyrAla: 2.308 ± 0.03
0.175TyrCys: 0.175 ± 0.008
1.227TyrAsp: 1.227 ± 0.028
1.006TyrGlu: 1.006 ± 0.02
0.64TyrPhe: 0.64 ± 0.018
1.87TyrGly: 1.87 ± 0.03
0.438TyrHis: 0.438 ± 0.013
0.417TyrIle: 0.417 ± 0.014
0.328TyrLys: 0.328 ± 0.012
2.154TyrLeu: 2.154 ± 0.031
0.217TyrMet: 0.217 ± 0.012
0.389TyrAsn: 0.389 ± 0.014
1.087TyrPro: 1.087 ± 0.02
0.575TyrGln: 0.575 ± 0.016
1.889TyrArg: 1.889 ± 0.027
1.053TyrSer: 1.053 ± 0.024
1.037TyrThr: 1.037 ± 0.023
1.615TyrVal: 1.615 ± 0.03
0.373TyrTrp: 0.373 ± 0.013
0.449TyrTyr: 0.449 ± 0.014
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7717 proteins (2556809 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski