Amino acid dipepetide frequency for Albimonas pacifica

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	26.09AlaAla: 26.09 ± 0.224	1.333AlaCys: 1.333 ± 0.03	7.791AlaAsp: 7.791 ± 0.078	10.659AlaGlu: 10.659 ± 0.101	4.805AlaPhe: 4.805 ± 0.052	14.01AlaGly: 14.01 ± 0.14	2.452AlaHis: 2.452 ± 0.043	5.578AlaIle: 5.578 ± 0.061	3.112AlaLys: 3.112 ± 0.059	17.268AlaLeu: 17.268 ± 0.137	4.298AlaMet: 4.298 ± 0.057	2.225AlaAsn: 2.225 ± 0.039	9.643AlaPro: 9.643 ± 0.114	4.527AlaGln: 4.527 ± 0.054	12.822AlaArg: 12.822 ± 0.119	6.355AlaSer: 6.355 ± 0.074	6.193AlaThr: 6.193 ± 0.072	9.71AlaVal: 9.71 ± 0.081	2.276AlaTrp: 2.276 ± 0.039	2.447AlaTyr: 2.447 ± 0.038	0.0AlaXaa: 0.0 ± 0.0
Cys	1.317CysAla: 1.317 ± 0.03	0.112CysCys: 0.112 ± 0.008	0.507CysAsp: 0.507 ± 0.017	0.444CysGlu: 0.444 ± 0.017	0.307CysPhe: 0.307 ± 0.014	0.945CysGly: 0.945 ± 0.025	0.217CysHis: 0.217 ± 0.014	0.312CysIle: 0.312 ± 0.015	0.142CysLys: 0.142 ± 0.01	0.814CysLeu: 0.814 ± 0.023	0.138CysMet: 0.138 ± 0.008	0.156CysAsn: 0.156 ± 0.009	0.48CysPro: 0.48 ± 0.02	0.154CysGln: 0.154 ± 0.009	0.63CysArg: 0.63 ± 0.02	0.384CysSer: 0.384 ± 0.017	0.411CysThr: 0.411 ± 0.014	0.591CysVal: 0.591 ± 0.02	0.138CysTrp: 0.138 ± 0.007	0.156CysTyr: 0.156 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	8.735AspAla: 8.735 ± 0.078	0.472AspCys: 0.472 ± 0.018	3.376AspAsp: 3.376 ± 0.091	3.383AspGlu: 3.383 ± 0.053	2.09AspPhe: 2.09 ± 0.035	5.705AspGly: 5.705 ± 0.087	1.144AspHis: 1.144 ± 0.026	1.871AspIle: 1.871 ± 0.036	1.027AspLys: 1.027 ± 0.024	6.43AspLeu: 6.43 ± 0.064	1.261AspMet: 1.261 ± 0.03	0.71AspAsn: 0.71 ± 0.022	4.717AspPro: 4.717 ± 0.056	1.366AspGln: 1.366 ± 0.032	4.899AspArg: 4.899 ± 0.068	1.656AspSer: 1.656 ± 0.038	1.758AspThr: 1.758 ± 0.04	4.2AspVal: 4.2 ± 0.085	1.164AspTrp: 1.164 ± 0.028	1.295AspTyr: 1.295 ± 0.03	0.0AspXaa: 0.0 ± 0.0
Glu	11.175GluAla: 11.175 ± 0.098	0.323GluCys: 0.323 ± 0.014	3.289GluAsp: 3.289 ± 0.05	3.414GluGlu: 3.414 ± 0.063	1.671GluPhe: 1.671 ± 0.033	5.977GluGly: 5.977 ± 0.068	1.045GluHis: 1.045 ± 0.027	3.667GluIle: 3.667 ± 0.052	1.692GluLys: 1.692 ± 0.041	5.424GluLeu: 5.424 ± 0.053	1.656GluMet: 1.656 ± 0.035	1.155GluAsn: 1.155 ± 0.025	3.095GluPro: 3.095 ± 0.047	1.657GluGln: 1.657 ± 0.03	5.273GluArg: 5.273 ± 0.07	2.201GluSer: 2.201 ± 0.037	4.169GluThr: 4.169 ± 0.055	4.278GluVal: 4.278 ± 0.061	0.769GluTrp: 0.769 ± 0.022	0.826GluTyr: 0.826 ± 0.026	0.0GluXaa: 0.0 ± 0.0
Phe	5.026PheAla: 5.026 ± 0.058	0.383PheCys: 0.383 ± 0.015	2.507PheAsp: 2.507 ± 0.045	2.243PheGlu: 2.243 ± 0.036	1.171PhePhe: 1.171 ± 0.027	3.586PheGly: 3.586 ± 0.051	0.727PheHis: 0.727 ± 0.021	1.148PheIle: 1.148 ± 0.024	0.654PheLys: 0.654 ± 0.022	3.163PheLeu: 3.163 ± 0.051	0.692PheMet: 0.692 ± 0.022	0.778PheAsn: 0.778 ± 0.022	1.559PhePro: 1.559 ± 0.032	0.923PheGln: 0.923 ± 0.025	2.286PheArg: 2.286 ± 0.041	1.784PheSer: 1.784 ± 0.035	1.494PheThr: 1.494 ± 0.028	2.524PheVal: 2.524 ± 0.043	0.504PheTrp: 0.504 ± 0.017	0.694PheTyr: 0.694 ± 0.02	0.0PheXaa: 0.0 ± 0.0
Gly	13.49GlyAla: 13.49 ± 0.129	0.897GlyCys: 0.897 ± 0.024	5.214GlyAsp: 5.214 ± 0.11	6.029GlyGlu: 6.029 ± 0.066	3.67GlyPhe: 3.67 ± 0.046	9.851GlyGly: 9.851 ± 0.233	1.661GlyHis: 1.661 ± 0.034	3.492GlyIle: 3.492 ± 0.043	2.363GlyLys: 2.363 ± 0.05	10.124GlyLeu: 10.124 ± 0.088	2.61GlyMet: 2.61 ± 0.044	1.399GlyAsn: 1.399 ± 0.035	5.118GlyPro: 5.118 ± 0.069	2.373GlyGln: 2.373 ± 0.043	7.947GlyArg: 7.947 ± 0.076	3.96GlySer: 3.96 ± 0.072	3.644GlyThr: 3.644 ± 0.051	7.17GlyVal: 7.17 ± 0.068	1.788GlyTrp: 1.788 ± 0.032	2.018GlyTyr: 2.018 ± 0.039	0.001GlyXaa: 0.001 ± 0.001
His	2.7HisAla: 2.7 ± 0.045	0.209HisCys: 0.209 ± 0.012	1.222HisAsp: 1.222 ± 0.028	1.016HisGlu: 1.016 ± 0.028	0.636HisPhe: 0.636 ± 0.018	1.967HisGly: 1.967 ± 0.037	0.473HisHis: 0.473 ± 0.017	0.585HisIle: 0.585 ± 0.02	0.307HisLys: 0.307 ± 0.015	1.828HisLeu: 1.828 ± 0.033	0.427HisMet: 0.427 ± 0.016	0.29HisAsn: 0.29 ± 0.011	1.405HisPro: 1.405 ± 0.034	0.398HisGln: 0.398 ± 0.019	1.346HisArg: 1.346 ± 0.034	0.702HisSer: 0.702 ± 0.022	0.569HisThr: 0.569 ± 0.019	1.517HisVal: 1.517 ± 0.03	0.287HisTrp: 0.287 ± 0.012	0.405HisTyr: 0.405 ± 0.018	0.0HisXaa: 0.0 ± 0.0
Ile	6.188IleAla: 6.188 ± 0.06	0.474IleCys: 0.474 ± 0.017	2.741IleAsp: 2.741 ± 0.045	3.213IleGlu: 3.213 ± 0.051	1.38IlePhe: 1.38 ± 0.031	4.06IleGly: 4.06 ± 0.054	0.801IleHis: 0.801 ± 0.025	1.132IleIle: 1.132 ± 0.032	0.801IleLys: 0.801 ± 0.024	3.988IleLeu: 3.988 ± 0.059	0.675IleMet: 0.675 ± 0.022	0.876IleAsn: 0.876 ± 0.025	2.137IlePro: 2.137 ± 0.037	0.876IleGln: 0.876 ± 0.021	2.981IleArg: 2.981 ± 0.04	2.212IleSer: 2.212 ± 0.039	1.766IleThr: 1.766 ± 0.034	3.27IleVal: 3.27 ± 0.044	0.544IleTrp: 0.544 ± 0.018	0.86IleTyr: 0.86 ± 0.024	0.0IleXaa: 0.0 ± 0.0
Lys	3.271LysAla: 3.271 ± 0.052	0.116LysCys: 0.116 ± 0.008	1.173LysAsp: 1.173 ± 0.028	1.036LysGlu: 1.036 ± 0.03	0.617LysPhe: 0.617 ± 0.02	2.165LysGly: 2.165 ± 0.043	0.376LysHis: 0.376 ± 0.016	1.114LysIle: 1.114 ± 0.03	0.758LysLys: 0.758 ± 0.023	2.242LysLeu: 2.242 ± 0.042	0.603LysMet: 0.603 ± 0.018	0.451LysAsn: 0.451 ± 0.017	1.421LysPro: 1.421 ± 0.032	0.499LysGln: 0.499 ± 0.019	1.671LysArg: 1.671 ± 0.036	1.098LysSer: 1.098 ± 0.027	1.387LysThr: 1.387 ± 0.034	1.736LysVal: 1.736 ± 0.037	0.277LysTrp: 0.277 ± 0.013	0.419LysTyr: 0.419 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	17.284LeuAla: 17.284 ± 0.148	0.88LeuCys: 0.88 ± 0.023	6.437LeuAsp: 6.437 ± 0.069	5.898LeuGlu: 5.898 ± 0.062	3.227LeuPhe: 3.227 ± 0.045	9.198LeuGly: 9.198 ± 0.094	1.964LeuHis: 1.964 ± 0.036	4.104LeuIle: 4.104 ± 0.054	2.471LeuLys: 2.471 ± 0.042	9.098LeuLeu: 9.098 ± 0.098	2.319LeuMet: 2.319 ± 0.039	1.958LeuAsn: 1.958 ± 0.037	5.939LeuPro: 5.939 ± 0.067	2.287LeuGln: 2.287 ± 0.034	8.191LeuArg: 8.191 ± 0.086	5.932LeuSer: 5.932 ± 0.074	5.35LeuThr: 5.35 ± 0.06	6.9LeuVal: 6.9 ± 0.067	1.285LeuTrp: 1.285 ± 0.026	1.695LeuTyr: 1.695 ± 0.032	0.0LeuXaa: 0.0 ± 0.0
Met	3.388MetAla: 3.388 ± 0.047	0.151MetCys: 0.151 ± 0.009	1.236MetAsp: 1.236 ± 0.026	1.284MetGlu: 1.284 ± 0.032	0.656MetPhe: 0.656 ± 0.022	2.102MetGly: 2.102 ± 0.039	0.386MetHis: 0.386 ± 0.015	1.308MetIle: 1.308 ± 0.034	0.753MetLys: 0.753 ± 0.025	2.33MetLeu: 2.33 ± 0.043	0.634MetMet: 0.634 ± 0.02	0.615MetAsn: 0.615 ± 0.019	1.371MetPro: 1.371 ± 0.032	0.736MetGln: 0.736 ± 0.023	1.894MetArg: 1.894 ± 0.036	1.596MetSer: 1.596 ± 0.034	2.031MetThr: 2.031 ± 0.039	1.55MetVal: 1.55 ± 0.036	0.233MetTrp: 0.233 ± 0.012	0.244MetTyr: 0.244 ± 0.012	0.0MetXaa: 0.0 ± 0.0
Asn	2.519AsnAla: 2.519 ± 0.04	0.175AsnCys: 0.175 ± 0.01	0.943AsnAsp: 0.943 ± 0.034	0.83AsnGlu: 0.83 ± 0.024	0.647AsnPhe: 0.647 ± 0.018	1.722AsnGly: 1.722 ± 0.035	0.348AsnHis: 0.348 ± 0.014	0.767AsnIle: 0.767 ± 0.022	0.345AsnLys: 0.345 ± 0.017	2.014AsnLeu: 2.014 ± 0.038	0.427AsnMet: 0.427 ± 0.018	0.404AsnAsn: 0.404 ± 0.014	1.485AsnPro: 1.485 ± 0.032	0.423AsnGln: 0.423 ± 0.016	1.328AsnArg: 1.328 ± 0.027	0.715AsnSer: 0.715 ± 0.024	0.814AsnThr: 0.814 ± 0.023	1.397AsnVal: 1.397 ± 0.029	0.314AsnTrp: 0.314 ± 0.015	0.436AsnTyr: 0.436 ± 0.017	0.0AsnXaa: 0.0 ± 0.0
Pro	9.376ProAla: 9.376 ± 0.107	0.387ProCys: 0.387 ± 0.018	4.08ProAsp: 4.08 ± 0.052	4.99ProGlu: 4.99 ± 0.06	1.941ProPhe: 1.941 ± 0.031	6.191ProGly: 6.191 ± 0.067	1.041ProHis: 1.041 ± 0.026	2.033ProIle: 2.033 ± 0.037	1.257ProLys: 1.257 ± 0.035	5.35ProLeu: 5.35 ± 0.068	1.335ProMet: 1.335 ± 0.029	1.015ProAsn: 1.015 ± 0.026	3.797ProPro: 3.797 ± 0.065	1.608ProGln: 1.608 ± 0.032	4.185ProArg: 4.185 ± 0.059	2.891ProSer: 2.891 ± 0.043	2.48ProThr: 2.48 ± 0.036	4.243ProVal: 4.243 ± 0.058	0.885ProTrp: 0.885 ± 0.023	1.07ProTyr: 1.07 ± 0.024	0.0ProXaa: 0.0 ± 0.0
Gln	4.474GlnAla: 4.474 ± 0.053	0.148GlnCys: 0.148 ± 0.009	1.289GlnAsp: 1.289 ± 0.031	1.413GlnGlu: 1.413 ± 0.034	0.754GlnPhe: 0.754 ± 0.021	2.525GlnGly: 2.525 ± 0.043	0.416GlnHis: 0.416 ± 0.017	1.231GlnIle: 1.231 ± 0.029	0.637GlnLys: 0.637 ± 0.02	2.131GlnLeu: 2.131 ± 0.031	0.709GlnMet: 0.709 ± 0.018	0.484GlnAsn: 0.484 ± 0.018	1.442GlnPro: 1.442 ± 0.029	0.7GlnGln: 0.7 ± 0.024	1.883GlnArg: 1.883 ± 0.034	1.163GlnSer: 1.163 ± 0.029	1.429GlnThr: 1.429 ± 0.031	2.103GlnVal: 2.103 ± 0.036	0.301GlnTrp: 0.301 ± 0.012	0.36GlnTyr: 0.36 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	11.534ArgAla: 11.534 ± 0.105	0.542ArgCys: 0.542 ± 0.019	4.415ArgAsp: 4.415 ± 0.053	4.876ArgGlu: 4.876 ± 0.057	2.936ArgPhe: 2.936 ± 0.043	5.994ArgGly: 5.994 ± 0.064	1.533ArgHis: 1.533 ± 0.03	3.909ArgIle: 3.909 ± 0.05	1.796ArgLys: 1.796 ± 0.041	9.498ArgLeu: 9.498 ± 0.095	2.17ArgMet: 2.17 ± 0.038	1.408ArgAsn: 1.408 ± 0.029	4.999ArgPro: 4.999 ± 0.073	1.995ArgGln: 1.995 ± 0.038	7.86ArgArg: 7.86 ± 0.118	3.354ArgSer: 3.354 ± 0.049	3.241ArgThr: 3.241 ± 0.048	5.055ArgVal: 5.055 ± 0.053	1.244ArgTrp: 1.244 ± 0.031	1.433ArgTyr: 1.433 ± 0.026	0.0ArgXaa: 0.0 ± 0.0
Ser	6.233SerAla: 6.233 ± 0.069	0.348SerCys: 0.348 ± 0.014	2.594SerAsp: 2.594 ± 0.048	2.407SerGlu: 2.407 ± 0.037	1.803SerPhe: 1.803 ± 0.036	5.073SerGly: 5.073 ± 0.07	0.87SerHis: 0.87 ± 0.026	2.073SerIle: 2.073 ± 0.044	1.006SerLys: 1.006 ± 0.024	4.746SerLeu: 4.746 ± 0.062	1.033SerMet: 1.033 ± 0.022	0.91SerAsn: 0.91 ± 0.025	2.885SerPro: 2.885 ± 0.036	1.156SerGln: 1.156 ± 0.029	3.455SerArg: 3.455 ± 0.043	2.149SerSer: 2.149 ± 0.047	2.121SerThr: 2.121 ± 0.047	3.464SerVal: 3.464 ± 0.054	0.699SerTrp: 0.699 ± 0.02	0.913SerTyr: 0.913 ± 0.022	0.0SerXaa: 0.0 ± 0.0
Thr	6.141ThrAla: 6.141 ± 0.066	0.391ThrCys: 0.391 ± 0.015	2.341ThrAsp: 2.341 ± 0.048	2.601ThrGlu: 2.601 ± 0.042	1.619ThrPhe: 1.619 ± 0.031	4.916ThrGly: 4.916 ± 0.063	0.821ThrHis: 0.821 ± 0.019	1.93ThrIle: 1.93 ± 0.042	0.833ThrLys: 0.833 ± 0.024	5.659ThrLeu: 5.659 ± 0.067	0.951ThrMet: 0.951 ± 0.022	0.845ThrAsn: 0.845 ± 0.025	3.573ThrPro: 3.573 ± 0.041	1.137ThrGln: 1.137 ± 0.03	3.298ThrArg: 3.298 ± 0.043	2.13ThrSer: 2.13 ± 0.04	2.264ThrThr: 2.264 ± 0.049	3.765ThrVal: 3.765 ± 0.057	0.701ThrTrp: 0.701 ± 0.022	0.866ThrTyr: 0.866 ± 0.024	0.0ThrXaa: 0.0 ± 0.0
Val	10.374ValAla: 10.374 ± 0.088	0.698ValCys: 0.698 ± 0.021	4.065ValAsp: 4.065 ± 0.058	5.173ValGlu: 5.173 ± 0.06	2.7ValPhe: 2.7 ± 0.041	5.782ValGly: 5.782 ± 0.057	1.348ValHis: 1.348 ± 0.027	3.432ValIle: 3.432 ± 0.053	1.673ValLys: 1.673 ± 0.033	6.756ValLeu: 6.756 ± 0.067	1.827ValMet: 1.827 ± 0.038	1.597ValAsn: 1.597 ± 0.029	3.395ValPro: 3.395 ± 0.043	1.889ValGln: 1.889 ± 0.04	4.88ValArg: 4.88 ± 0.054	3.895ValSer: 3.895 ± 0.06	3.842ValThr: 3.842 ± 0.052	5.559ValVal: 5.559 ± 0.061	0.98ValTrp: 0.98 ± 0.027	1.414ValTyr: 1.414 ± 0.029	0.0ValXaa: 0.0 ± 0.0
Trp	1.71TrpAla: 1.71 ± 0.036	0.144TrpCys: 0.144 ± 0.009	0.745TrpAsp: 0.745 ± 0.023	0.746TrpGlu: 0.746 ± 0.021	0.55TrpPhe: 0.55 ± 0.019	1.143TrpGly: 1.143 ± 0.027	0.273TrpHis: 0.273 ± 0.013	0.701TrpIle: 0.701 ± 0.023	0.424TrpLys: 0.424 ± 0.016	1.736TrpLeu: 1.736 ± 0.034	0.384TrpMet: 0.384 ± 0.015	0.387TrpAsn: 0.387 ± 0.014	0.82TrpPro: 0.82 ± 0.022	0.426TrpGln: 0.426 ± 0.017	1.529TrpArg: 1.529 ± 0.032	0.912TrpSer: 0.912 ± 0.025	0.981TrpThr: 0.981 ± 0.027	0.833TrpVal: 0.833 ± 0.023	0.271TrpTrp: 0.271 ± 0.013	0.24TrpTyr: 0.24 ± 0.013	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.57TyrAla: 2.57 ± 0.044	0.175TyrCys: 0.175 ± 0.011	1.292TyrAsp: 1.292 ± 0.026	1.101TyrGlu: 1.101 ± 0.024	0.665TyrPhe: 0.665 ± 0.02	1.907TyrGly: 1.907 ± 0.036	0.392TyrHis: 0.392 ± 0.019	0.586TyrIle: 0.586 ± 0.02	0.38TyrLys: 0.38 ± 0.015	1.815TyrLeu: 1.815 ± 0.036	0.348TyrMet: 0.348 ± 0.015	0.392TyrAsn: 0.392 ± 0.015	0.876TyrPro: 0.876 ± 0.022	0.46TyrGln: 0.46 ± 0.014	1.434TyrArg: 1.434 ± 0.028	0.85TyrSer: 0.85 ± 0.023	0.838TyrThr: 0.838 ± 0.025	1.417TyrVal: 1.417 ± 0.028	0.296TyrTrp: 0.296 ± 0.014	0.421TyrTyr: 0.421 ± 0.018	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.001XaaGly: 0.001 ± 0.001	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.001XaaXaa: 0.001 ± 0.001

Statistics based on 5319 proteins (1748452 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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