Amino acid dipepetide frequency for Axonopus compressus streak virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.865AlaAla: 5.865 ± 1.025
3.91AlaCys: 3.91 ± 2.479
5.865AlaAsp: 5.865 ± 1.025
0.0AlaGlu: 0.0 ± 0.0
2.933AlaPhe: 2.933 ± 0.513
9.775AlaGly: 9.775 ± 4.773
0.0AlaHis: 0.0 ± 0.0
0.978AlaIle: 0.978 ± 0.735
0.978AlaLys: 0.978 ± 0.704
4.888AlaLeu: 4.888 ± 0.895
0.978AlaMet: 0.978 ± 0.704
5.865AlaAsn: 5.865 ± 2.639
3.91AlaPro: 3.91 ± 1.01
3.91AlaGln: 3.91 ± 1.12
7.82AlaArg: 7.82 ± 1.236
2.933AlaSer: 2.933 ± 1.067
1.955AlaThr: 1.955 ± 1.469
2.933AlaVal: 2.933 ± 0.513
2.933AlaTrp: 2.933 ± 1.494
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
1.955CysAla: 1.955 ± 0.649
1.955CysCys: 1.955 ± 1.469
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
2.933CysGly: 2.933 ± 1.067
2.933CysHis: 2.933 ± 0.513
0.978CysIle: 0.978 ± 0.704
1.955CysLys: 1.955 ± 1.469
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
2.933CysAsn: 2.933 ± 0.513
0.978CysPro: 0.978 ± 0.704
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
1.955CysThr: 1.955 ± 1.534
1.955CysVal: 1.955 ± 0.816
2.933CysTrp: 2.933 ± 1.383
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.91AspAla: 3.91 ± 1.088
0.0AspCys: 0.0 ± 0.0
5.865AspAsp: 5.865 ± 1.458
0.978AspGlu: 0.978 ± 0.704
3.91AspPhe: 3.91 ± 1.687
3.91AspGly: 3.91 ± 1.01
0.0AspHis: 0.0 ± 0.0
1.955AspIle: 1.955 ± 0.816
1.955AspLys: 1.955 ± 0.649
3.91AspLeu: 3.91 ± 1.838
0.0AspMet: 0.0 ± 0.0
1.955AspAsn: 1.955 ± 0.649
2.933AspPro: 2.933 ± 1.32
3.91AspGln: 3.91 ± 1.12
1.955AspArg: 1.955 ± 0.649
3.91AspSer: 3.91 ± 0.78
4.888AspThr: 4.888 ± 1.905
9.775AspVal: 9.775 ± 2.153
3.91AspTrp: 3.91 ± 0.78
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
2.933GluAla: 2.933 ± 1.067
0.978GluCys: 0.978 ± 0.704
4.888GluAsp: 4.888 ± 0.911
0.978GluGlu: 0.978 ± 0.704
1.955GluPhe: 1.955 ± 0.649
0.978GluGly: 0.978 ± 0.704
1.955GluHis: 1.955 ± 0.649
1.955GluIle: 1.955 ± 0.649
0.0GluLys: 0.0 ± 0.0
6.843GluLeu: 6.843 ± 1.609
0.0GluMet: 0.0 ± 0.0
1.955GluAsn: 1.955 ± 0.649
0.0GluPro: 0.0 ± 0.0
0.0GluGln: 0.0 ± 0.0
1.955GluArg: 1.955 ± 1.375
0.0GluSer: 0.0 ± 0.0
1.955GluThr: 1.955 ± 1.469
1.955GluVal: 1.955 ± 0.953
0.978GluTrp: 0.978 ± 0.735
1.955GluTyr: 1.955 ± 0.649
0.0GluXaa: 0.0 ± 0.0
Phe
0.978PheAla: 0.978 ± 1.399
2.933PheCys: 2.933 ± 0.513
3.91PheAsp: 3.91 ± 1.299
0.978PheGlu: 0.978 ± 0.704
1.955PhePhe: 1.955 ± 0.649
1.955PheGly: 1.955 ± 2.799
4.888PheHis: 4.888 ± 0.911
2.933PheIle: 2.933 ± 1.067
0.978PheLys: 0.978 ± 0.704
7.82PheLeu: 7.82 ± 0.941
0.0PheMet: 0.0 ± 0.0
1.955PheAsn: 1.955 ± 0.649
3.91PhePro: 3.91 ± 1.299
1.955PheGln: 1.955 ± 0.649
1.955PheArg: 1.955 ± 0.649
0.978PheSer: 0.978 ± 0.735
3.91PheThr: 3.91 ± 1.631
2.933PheVal: 2.933 ± 1.956
0.0PheTrp: 0.0 ± 0.0
0.978PheTyr: 0.978 ± 1.399
0.0PheXaa: 0.0 ± 0.0
Gly
6.843GlyAla: 6.843 ± 2.834
0.978GlyCys: 0.978 ± 0.735
1.955GlyAsp: 1.955 ± 0.816
1.955GlyGlu: 1.955 ± 0.649
6.843GlyPhe: 6.843 ± 1.609
9.775GlyGly: 9.775 ± 1.525
0.0GlyHis: 0.0 ± 0.0
3.91GlyIle: 3.91 ± 0.78
4.888GlyLys: 4.888 ± 0.895
0.0GlyLeu: 0.0 ± 0.0
0.978GlyMet: 0.978 ± 1.192
0.978GlyAsn: 0.978 ± 1.399
8.798GlyPro: 8.798 ± 3.387
2.933GlyGln: 2.933 ± 1.151
4.888GlyArg: 4.888 ± 0.895
9.775GlySer: 9.775 ± 1.444
10.753GlyThr: 10.753 ± 1.503
2.933GlyVal: 2.933 ± 0.513
0.0GlyTrp: 0.0 ± 0.0
0.978GlyTyr: 0.978 ± 0.735
0.0GlyXaa: 0.0 ± 0.0
His
1.955HisAla: 1.955 ± 0.649
1.955HisCys: 1.955 ± 0.649
1.955HisAsp: 1.955 ± 0.649
1.955HisGlu: 1.955 ± 0.649
0.0HisPhe: 0.0 ± 0.0
4.888HisGly: 4.888 ± 1.359
0.0HisHis: 0.0 ± 0.0
1.955HisIle: 1.955 ± 0.649
2.933HisLys: 2.933 ± 0.513
0.0HisLeu: 0.0 ± 0.0
0.0HisMet: 0.0 ± 0.0
1.955HisAsn: 1.955 ± 0.649
2.933HisPro: 2.933 ± 1.32
0.978HisGln: 0.978 ± 0.735
0.978HisArg: 0.978 ± 0.735
0.0HisSer: 0.0 ± 0.0
2.933HisThr: 2.933 ± 0.513
1.955HisVal: 1.955 ± 0.649
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
0.0IleAla: 0.0 ± 0.0
0.978IleCys: 0.978 ± 0.704
1.955IleAsp: 1.955 ± 0.816
0.0IleGlu: 0.0 ± 0.0
2.933IlePhe: 2.933 ± 0.513
5.865IleGly: 5.865 ± 1.182
3.91IleHis: 3.91 ± 1.299
0.0IleIle: 0.0 ± 0.0
2.933IleLys: 2.933 ± 1.335
4.888IleLeu: 4.888 ± 0.911
2.933IleMet: 2.933 ± 0.718
0.0IleAsn: 0.0 ± 0.0
2.933IlePro: 2.933 ± 1.335
1.955IleGln: 1.955 ± 0.649
0.0IleArg: 0.0 ± 0.0
0.0IleSer: 0.0 ± 0.0
3.91IleThr: 3.91 ± 1.299
1.955IleVal: 1.955 ± 1.409
0.0IleTrp: 0.0 ± 0.0
2.933IleTyr: 2.933 ± 0.513
0.0IleXaa: 0.0 ± 0.0
Lys
4.888LysAla: 4.888 ± 0.895
0.0LysCys: 0.0 ± 0.0
6.843LysAsp: 6.843 ± 1.809
0.0LysGlu: 0.0 ± 0.0
0.978LysPhe: 0.978 ± 0.735
0.978LysGly: 0.978 ± 0.704
0.0LysHis: 0.0 ± 0.0
0.978LysIle: 0.978 ± 0.835
3.91LysLys: 3.91 ± 1.687
4.888LysLeu: 4.888 ± 1.077
0.0LysMet: 0.0 ± 0.0
0.978LysAsn: 0.978 ± 0.735
0.0LysPro: 0.0 ± 0.0
1.955LysGln: 1.955 ± 0.649
3.91LysArg: 3.91 ± 1.088
3.91LysSer: 3.91 ± 0.78
0.978LysThr: 0.978 ± 0.735
0.978LysVal: 0.978 ± 0.735
0.0LysTrp: 0.0 ± 0.0
2.933LysTyr: 2.933 ± 2.113
0.0LysXaa: 0.0 ± 0.0
Leu
9.775LeuAla: 9.775 ± 2.478
0.0LeuCys: 0.0 ± 0.0
0.978LeuAsp: 0.978 ± 0.735
0.978LeuGlu: 0.978 ± 0.735
3.91LeuPhe: 3.91 ± 1.01
3.91LeuGly: 3.91 ± 2.66
3.91LeuHis: 3.91 ± 2.111
3.91LeuIle: 3.91 ± 1.687
2.933LeuLys: 2.933 ± 1.151
11.73LeuLeu: 11.73 ± 6.069
1.955LeuMet: 1.955 ± 0.649
1.955LeuAsn: 1.955 ± 0.649
2.933LeuPro: 2.933 ± 1.956
3.91LeuGln: 3.91 ± 1.12
2.933LeuArg: 2.933 ± 0.513
9.775LeuSer: 9.775 ± 0.341
3.91LeuThr: 3.91 ± 1.01
1.955LeuVal: 1.955 ± 1.534
0.0LeuTrp: 0.0 ± 0.0
3.91LeuTyr: 3.91 ± 1.631
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
0.978MetGlu: 0.978 ± 1.399
2.933MetPhe: 2.933 ± 1.151
0.978MetGly: 0.978 ± 0.735
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
0.0MetLeu: 0.0 ± 0.0
0.0MetMet: 0.0 ± 0.74
2.933MetAsn: 2.933 ± 1.32
0.978MetPro: 0.978 ± 0.735
0.0MetGln: 0.0 ± 0.0
0.978MetArg: 0.978 ± 0.704
0.0MetSer: 0.0 ± 0.0
2.933MetThr: 2.933 ± 1.067
0.978MetVal: 0.978 ± 0.735
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.955AsnAla: 1.955 ± 0.953
0.978AsnCys: 0.978 ± 0.704
4.888AsnAsp: 4.888 ± 0.895
0.978AsnGlu: 0.978 ± 0.735
0.978AsnPhe: 0.978 ± 0.735
2.933AsnGly: 2.933 ± 0.513
0.0AsnHis: 0.0 ± 0.0
7.82AsnIle: 7.82 ± 2.597
2.933AsnLys: 2.933 ± 0.513
1.955AsnLeu: 1.955 ± 0.649
0.0AsnMet: 0.0 ± 0.0
2.933AsnAsn: 2.933 ± 1.067
0.978AsnPro: 0.978 ± 0.704
0.978AsnGln: 0.978 ± 0.835
1.955AsnArg: 1.955 ± 0.953
0.978AsnSer: 0.978 ± 0.735
4.888AsnThr: 4.888 ± 1.359
1.955AsnVal: 1.955 ± 1.409
1.955AsnTrp: 1.955 ± 0.649
2.933AsnTyr: 2.933 ± 1.067
0.0AsnXaa: 0.0 ± 0.0
Pro
4.888ProAla: 4.888 ± 2.386
1.955ProCys: 1.955 ± 0.816
2.933ProAsp: 2.933 ± 0.513
4.888ProGlu: 4.888 ± 1.905
3.91ProPhe: 3.91 ± 1.215
4.888ProGly: 4.888 ± 1.239
1.955ProHis: 1.955 ± 0.649
0.0ProIle: 0.0 ± 0.0
0.978ProLys: 0.978 ± 0.704
1.955ProLeu: 1.955 ± 1.375
0.978ProMet: 0.978 ± 0.622
1.955ProAsn: 1.955 ± 0.649
6.843ProPro: 6.843 ± 2.037
4.888ProGln: 4.888 ± 1.239
7.82ProArg: 7.82 ± 2.176
6.843ProSer: 6.843 ± 1.529
4.888ProThr: 4.888 ± 0.895
0.978ProVal: 0.978 ± 1.399
0.0ProTrp: 0.0 ± 0.0
4.888ProTyr: 4.888 ± 1.905
0.0ProXaa: 0.0 ± 0.0
Gln
3.91GlnAla: 3.91 ± 1.468
0.0GlnCys: 0.0 ± 0.0
1.955GlnAsp: 1.955 ± 0.953
2.933GlnGlu: 2.933 ± 1.32
0.0GlnPhe: 0.0 ± 0.0
2.933GlnGly: 2.933 ± 1.32
0.978GlnHis: 0.978 ± 0.835
0.0GlnIle: 0.0 ± 0.0
0.978GlnLys: 0.978 ± 0.704
0.0GlnLeu: 0.0 ± 0.0
0.0GlnMet: 0.0 ± 0.0
2.933GlnAsn: 2.933 ± 1.067
4.888GlnPro: 4.888 ± 1.34
0.978GlnGln: 0.978 ± 0.835
3.91GlnArg: 3.91 ± 0.78
3.91GlnSer: 3.91 ± 1.299
4.888GlnThr: 4.888 ± 1.239
2.933GlnVal: 2.933 ± 1.956
0.978GlnTrp: 0.978 ± 0.835
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
2.933ArgAla: 2.933 ± 1.067
1.955ArgCys: 1.955 ± 0.649
3.91ArgAsp: 3.91 ± 1.299
2.933ArgGlu: 2.933 ± 0.513
3.91ArgPhe: 3.91 ± 1.01
6.843ArgGly: 6.843 ± 0.78
2.933ArgHis: 2.933 ± 1.384
0.0ArgIle: 0.0 ± 0.0
1.955ArgLys: 1.955 ± 0.649
3.91ArgLeu: 3.91 ± 1.01
0.978ArgMet: 0.978 ± 1.399
4.888ArgAsn: 4.888 ± 1.077
3.91ArgPro: 3.91 ± 0.78
1.955ArgGln: 1.955 ± 1.471
10.753ArgArg: 10.753 ± 5.396
7.82ArgSer: 7.82 ± 1.236
3.91ArgThr: 3.91 ± 1.737
2.933ArgVal: 2.933 ± 0.513
0.978ArgTrp: 0.978 ± 0.735
0.0ArgTyr: 0.0 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
3.91SerAla: 3.91 ± 1.088
0.978SerCys: 0.978 ± 0.735
0.0SerAsp: 0.0 ± 0.0
3.91SerGlu: 3.91 ± 0.78
2.933SerPhe: 2.933 ± 1.067
3.91SerGly: 3.91 ± 1.088
0.0SerHis: 0.0 ± 0.0
4.888SerIle: 4.888 ± 1.077
1.955SerLys: 1.955 ± 0.649
9.775SerLeu: 9.775 ± 1.553
0.0SerMet: 0.0 ± 0.0
0.0SerAsn: 0.0 ± 0.0
11.73SerPro: 11.73 ± 3.247
2.933SerGln: 2.933 ± 1.383
6.843SerArg: 6.843 ± 1.609
15.64SerSer: 15.64 ± 2.192
3.91SerThr: 3.91 ± 0.78
2.933SerVal: 2.933 ± 1.494
0.0SerTrp: 0.0 ± 0.0
6.843SerTyr: 6.843 ± 1.719
0.0SerXaa: 0.0 ± 0.0
Thr
5.865ThrAla: 5.865 ± 1.098
0.0ThrCys: 0.0 ± 0.0
1.955ThrAsp: 1.955 ± 0.649
3.91ThrGlu: 3.91 ± 1.01
2.933ThrPhe: 2.933 ± 1.151
6.843ThrGly: 6.843 ± 1.534
0.978ThrHis: 0.978 ± 0.735
1.955ThrIle: 1.955 ± 1.469
0.0ThrLys: 0.0 ± 0.0
3.91ThrLeu: 3.91 ± 3.067
0.978ThrMet: 0.978 ± 0.735
3.91ThrAsn: 3.91 ± 2.939
6.843ThrPro: 6.843 ± 1.609
0.0ThrGln: 0.0 ± 0.0
3.91ThrArg: 3.91 ± 0.78
8.798ThrSer: 8.798 ± 1.476
2.933ThrThr: 2.933 ± 1.941
6.843ThrVal: 6.843 ± 1.609
1.955ThrTrp: 1.955 ± 0.816
3.91ThrTyr: 3.91 ± 1.299
0.0ThrXaa: 0.0 ± 0.0
Val
0.0ValAla: 0.0 ± 0.0
2.933ValCys: 2.933 ± 2.204
3.91ValAsp: 3.91 ± 1.088
0.978ValGlu: 0.978 ± 0.704
0.978ValPhe: 0.978 ± 0.735
2.933ValGly: 2.933 ± 2.843
2.933ValHis: 2.933 ± 0.513
1.955ValIle: 1.955 ± 1.409
2.933ValLys: 2.933 ± 0.513
5.865ValLeu: 5.865 ± 2.302
2.933ValMet: 2.933 ± 1.32
2.933ValAsn: 2.933 ± 1.335
0.978ValPro: 0.978 ± 0.735
1.955ValGln: 1.955 ± 0.649
3.91ValArg: 3.91 ± 1.088
3.91ValSer: 3.91 ± 1.737
2.933ValThr: 2.933 ± 1.151
2.933ValVal: 2.933 ± 1.335
0.978ValTrp: 0.978 ± 0.735
7.82ValTyr: 7.82 ± 1.328
0.0ValXaa: 0.0 ± 0.0
Trp
1.955TrpAla: 1.955 ± 0.816
0.0TrpCys: 0.0 ± 0.0
1.955TrpAsp: 1.955 ± 0.953
1.955TrpGlu: 1.955 ± 0.649
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
2.933TrpLys: 2.933 ± 1.384
1.955TrpLeu: 1.955 ± 0.953
0.978TrpMet: 0.978 ± 0.704
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
1.955TrpGln: 1.955 ± 0.816
1.955TrpArg: 1.955 ± 2.799
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
2.933TrpVal: 2.933 ± 0.513
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.91TyrAla: 3.91 ± 1.12
0.978TyrCys: 0.978 ± 0.704
3.91TyrAsp: 3.91 ± 0.78
2.933TyrGlu: 2.933 ± 1.067
3.91TyrPhe: 3.91 ± 0.78
2.933TyrGly: 2.933 ± 1.067
1.955TyrHis: 1.955 ± 0.649
3.91TyrIle: 3.91 ± 0.78
0.978TyrLys: 0.978 ± 0.735
0.978TyrLeu: 0.978 ± 0.704
0.0TyrMet: 0.0 ± 0.0
1.955TyrAsn: 1.955 ± 0.816
1.955TyrPro: 1.955 ± 0.649
1.955TyrGln: 1.955 ± 0.649
0.978TyrArg: 0.978 ± 1.399
3.91TyrSer: 3.91 ± 1.12
0.0TyrThr: 0.0 ± 0.0
1.955TyrVal: 1.955 ± 1.534
0.978TyrTrp: 0.978 ± 0.704
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1024 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski