Amino acid dipepetide frequency for Tuwongella immobilis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.12AlaAla: 11.12 ± 0.102	0.957AlaCys: 0.957 ± 0.027	5.97AlaAsp: 5.97 ± 0.062	6.325AlaGlu: 6.325 ± 0.076	3.349AlaPhe: 3.349 ± 0.048	7.838AlaGly: 7.838 ± 0.118	1.616AlaHis: 1.616 ± 0.034	5.968AlaIle: 5.968 ± 0.058	4.267AlaLys: 4.267 ± 0.068	8.511AlaLeu: 8.511 ± 0.085	2.786AlaMet: 2.786 ± 0.047	3.582AlaAsn: 3.582 ± 0.067	5.201AlaPro: 5.201 ± 0.068	3.593AlaGln: 3.593 ± 0.055	5.765AlaArg: 5.765 ± 0.084	5.74AlaSer: 5.74 ± 0.073	6.12AlaThr: 6.12 ± 0.083	6.725AlaVal: 6.725 ± 0.07	1.473AlaTrp: 1.473 ± 0.027	2.028AlaTyr: 2.028 ± 0.041	0.0AlaXaa: 0.0 ± 0.0
Cys	0.66CysAla: 0.66 ± 0.023	0.168CysCys: 0.168 ± 0.012	0.595CysAsp: 0.595 ± 0.019	0.566CysGlu: 0.566 ± 0.021	0.375CysPhe: 0.375 ± 0.014	0.903CysGly: 0.903 ± 0.026	0.338CysHis: 0.338 ± 0.015	0.411CysIle: 0.411 ± 0.015	0.277CysLys: 0.277 ± 0.014	1.058CysLeu: 1.058 ± 0.03	0.181CysMet: 0.181 ± 0.011	0.238CysAsn: 0.238 ± 0.013	0.599CysPro: 0.599 ± 0.02	0.467CysGln: 0.467 ± 0.017	0.696CysArg: 0.696 ± 0.02	0.57CysSer: 0.57 ± 0.019	0.432CysThr: 0.432 ± 0.017	0.597CysVal: 0.597 ± 0.022	0.173CysTrp: 0.173 ± 0.009	0.261CysTyr: 0.261 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	6.067AspAla: 6.067 ± 0.057	0.571AspCys: 0.571 ± 0.018	3.106AspAsp: 3.106 ± 0.05	2.937AspGlu: 2.937 ± 0.043	2.201AspPhe: 2.201 ± 0.034	5.058AspGly: 5.058 ± 0.101	1.174AspHis: 1.174 ± 0.022	2.003AspIle: 2.003 ± 0.038	1.256AspLys: 1.256 ± 0.033	5.881AspLeu: 5.881 ± 0.064	0.767AspMet: 0.767 ± 0.02	1.258AspAsn: 1.258 ± 0.036	3.85AspPro: 3.85 ± 0.053	2.034AspGln: 2.034 ± 0.029	4.656AspArg: 4.656 ± 0.068	3.388AspSer: 3.388 ± 0.048	2.361AspThr: 2.361 ± 0.051	3.364AspVal: 3.364 ± 0.052	1.228AspTrp: 1.228 ± 0.026	1.323AspTyr: 1.323 ± 0.025	0.0AspXaa: 0.0 ± 0.0
Glu	5.422GluAla: 5.422 ± 0.07	0.503GluCys: 0.503 ± 0.017	2.105GluAsp: 2.105 ± 0.041	2.641GluGlu: 2.641 ± 0.057	2.265GluPhe: 2.265 ± 0.035	3.113GluGly: 3.113 ± 0.043	1.12GluHis: 1.12 ± 0.027	3.261GluIle: 3.261 ± 0.043	2.167GluLys: 2.167 ± 0.046	6.647GluLeu: 6.647 ± 0.075	1.572GluMet: 1.572 ± 0.032	1.515GluAsn: 1.515 ± 0.029	3.101GluPro: 3.101 ± 0.052	2.945GluGln: 2.945 ± 0.057	4.426GluArg: 4.426 ± 0.067	4.373GluSer: 4.373 ± 0.061	3.094GluThr: 3.094 ± 0.043	3.655GluVal: 3.655 ± 0.046	1.036GluTrp: 1.036 ± 0.028	1.279GluTyr: 1.279 ± 0.028	0.0GluXaa: 0.0 ± 0.0
Phe	3.779PheAla: 3.779 ± 0.052	0.429PheCys: 0.429 ± 0.018	2.394PheAsp: 2.394 ± 0.038	2.017PheGlu: 2.017 ± 0.034	1.339PhePhe: 1.339 ± 0.029	3.397PheGly: 3.397 ± 0.058	0.801PheHis: 0.801 ± 0.022	1.249PheIle: 1.249 ± 0.027	0.805PheLys: 0.805 ± 0.023	3.6PheLeu: 3.6 ± 0.049	0.498PheMet: 0.498 ± 0.018	1.023PheAsn: 1.023 ± 0.03	2.013PhePro: 2.013 ± 0.04	1.544PheGln: 1.544 ± 0.031	2.864PheArg: 2.864 ± 0.041	2.103PheSer: 2.103 ± 0.034	2.119PheThr: 2.119 ± 0.041	2.53PheVal: 2.53 ± 0.043	0.621PheTrp: 0.621 ± 0.02	0.797PheTyr: 0.797 ± 0.021	0.0PheXaa: 0.0 ± 0.0
Gly	5.837GlyAla: 5.837 ± 0.108	0.938GlyCys: 0.938 ± 0.024	4.338GlyAsp: 4.338 ± 0.08	4.316GlyGlu: 4.316 ± 0.049	3.077GlyPhe: 3.077 ± 0.05	7.055GlyGly: 7.055 ± 0.229	1.486GlyHis: 1.486 ± 0.033	4.472GlyIle: 4.472 ± 0.057	3.797GlyLys: 3.797 ± 0.059	7.289GlyLeu: 7.289 ± 0.066	2.37GlyMet: 2.37 ± 0.04	2.935GlyAsn: 2.935 ± 0.09	3.587GlyPro: 3.587 ± 0.056	3.152GlyGln: 3.152 ± 0.049	4.826GlyArg: 4.826 ± 0.059	5.002GlySer: 5.002 ± 0.131	5.205GlyThr: 5.205 ± 0.151	5.555GlyVal: 5.555 ± 0.084	1.492GlyTrp: 1.492 ± 0.033	2.108GlyTyr: 2.108 ± 0.045	0.0GlyXaa: 0.0 ± 0.0
His	2.072HisAla: 2.072 ± 0.04	0.267HisCys: 0.267 ± 0.012	1.121HisAsp: 1.121 ± 0.029	1.049HisGlu: 1.049 ± 0.026	0.803HisPhe: 0.803 ± 0.023	1.634HisGly: 1.634 ± 0.035	0.655HisHis: 0.655 ± 0.022	0.728HisIle: 0.728 ± 0.018	0.409HisLys: 0.409 ± 0.014	2.285HisLeu: 2.285 ± 0.042	0.255HisMet: 0.255 ± 0.012	0.5HisAsn: 0.5 ± 0.017	1.668HisPro: 1.668 ± 0.035	0.885HisGln: 0.885 ± 0.022	1.686HisArg: 1.686 ± 0.032	1.156HisSer: 1.156 ± 0.027	0.999HisThr: 0.999 ± 0.025	1.148HisVal: 1.148 ± 0.022	0.439HisTrp: 0.439 ± 0.016	0.537HisTyr: 0.537 ± 0.018	0.0HisXaa: 0.0 ± 0.0
Ile	5.843IleAla: 5.843 ± 0.062	0.549IleCys: 0.549 ± 0.02	3.431IleAsp: 3.431 ± 0.049	3.144IleGlu: 3.144 ± 0.047	1.594IlePhe: 1.594 ± 0.029	4.407IleGly: 4.407 ± 0.053	1.185IleHis: 1.185 ± 0.026	2.087IleIle: 2.087 ± 0.038	1.066IleLys: 1.066 ± 0.027	5.056IleLeu: 5.056 ± 0.067	0.622IleMet: 0.622 ± 0.021	1.427IleAsn: 1.427 ± 0.036	3.401IlePro: 3.401 ± 0.052	2.031IleGln: 2.031 ± 0.034	4.483IleArg: 4.483 ± 0.052	2.918IleSer: 2.918 ± 0.054	3.011IleThr: 3.011 ± 0.074	3.804IleVal: 3.804 ± 0.046	0.781IleTrp: 0.781 ± 0.02	1.116IleTyr: 1.116 ± 0.024	0.0IleXaa: 0.0 ± 0.0
Lys	3.133LysAla: 3.133 ± 0.059	0.273LysCys: 0.273 ± 0.014	1.505LysAsp: 1.505 ± 0.034	1.562LysGlu: 1.562 ± 0.037	1.073LysPhe: 1.073 ± 0.028	2.036LysGly: 2.036 ± 0.039	0.647LysHis: 0.647 ± 0.017	1.852LysIle: 1.852 ± 0.033	1.421LysLys: 1.421 ± 0.045	3.968LysLeu: 3.968 ± 0.067	0.912LysMet: 0.912 ± 0.024	1.052LysAsn: 1.052 ± 0.027	2.73LysPro: 2.73 ± 0.05	1.578LysGln: 1.578 ± 0.035	2.331LysArg: 2.331 ± 0.045	2.235LysSer: 2.235 ± 0.042	1.869LysThr: 1.869 ± 0.038	2.284LysVal: 2.284 ± 0.044	0.457LysTrp: 0.457 ± 0.016	0.78LysTyr: 0.78 ± 0.022	0.0LysXaa: 0.0 ± 0.0
Leu	11.824LeuAla: 11.824 ± 0.11	0.864LeuCys: 0.864 ± 0.024	5.8LeuAsp: 5.8 ± 0.062	5.965LeuGlu: 5.965 ± 0.072	3.354LeuPhe: 3.354 ± 0.049	7.782LeuGly: 7.782 ± 0.069	2.046LeuHis: 2.046 ± 0.046	4.951LeuIle: 4.951 ± 0.059	3.49LeuLys: 3.49 ± 0.066	10.636LeuLeu: 10.636 ± 0.131	2.146LeuMet: 2.146 ± 0.04	3.074LeuAsn: 3.074 ± 0.039	6.877LeuPro: 6.877 ± 0.077	4.282LeuGln: 4.282 ± 0.054	7.511LeuArg: 7.511 ± 0.082	5.923LeuSer: 5.923 ± 0.062	6.551LeuThr: 6.551 ± 0.081	6.915LeuVal: 6.915 ± 0.069	1.31LeuTrp: 1.31 ± 0.028	1.873LeuTyr: 1.873 ± 0.034	0.0LeuXaa: 0.0 ± 0.0
Met	2.292MetAla: 2.292 ± 0.036	0.136MetCys: 0.136 ± 0.008	1.018MetAsp: 1.018 ± 0.022	1.094MetGlu: 1.094 ± 0.027	0.634MetPhe: 0.634 ± 0.02	1.654MetGly: 1.654 ± 0.033	0.472MetHis: 0.472 ± 0.017	1.303MetIle: 1.303 ± 0.028	0.755MetLys: 0.755 ± 0.02	2.719MetLeu: 2.719 ± 0.048	0.611MetMet: 0.611 ± 0.017	0.823MetAsn: 0.823 ± 0.025	1.738MetPro: 1.738 ± 0.036	0.984MetGln: 0.984 ± 0.02	1.708MetArg: 1.708 ± 0.034	1.398MetSer: 1.398 ± 0.03	1.501MetThr: 1.501 ± 0.03	1.533MetVal: 1.533 ± 0.031	0.239MetTrp: 0.239 ± 0.012	0.303MetTyr: 0.303 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	3.018AsnAla: 3.018 ± 0.051	0.325AsnCys: 0.325 ± 0.016	1.798AsnAsp: 1.798 ± 0.042	1.421AsnGlu: 1.421 ± 0.025	1.094AsnPhe: 1.094 ± 0.028	3.058AsnGly: 3.058 ± 0.082	0.741AsnHis: 0.741 ± 0.022	1.268AsnIle: 1.268 ± 0.034	0.704AsnLys: 0.704 ± 0.023	3.248AsnLeu: 3.248 ± 0.049	0.439AsnMet: 0.439 ± 0.015	0.983AsnAsn: 0.983 ± 0.038	2.773AsnPro: 2.773 ± 0.047	1.403AsnGln: 1.403 ± 0.031	2.808AsnArg: 2.808 ± 0.042	1.975AsnSer: 1.975 ± 0.054	1.451AsnThr: 1.451 ± 0.053	1.887AsnVal: 1.887 ± 0.058	0.618AsnTrp: 0.618 ± 0.017	0.783AsnTyr: 0.783 ± 0.022	0.0AsnXaa: 0.0 ± 0.0
Pro	6.335ProAla: 6.335 ± 0.08	0.369ProCys: 0.369 ± 0.016	3.676ProAsp: 3.676 ± 0.046	4.496ProGlu: 4.496 ± 0.067	2.071ProPhe: 2.071 ± 0.037	4.778ProGly: 4.778 ± 0.066	1.183ProHis: 1.183 ± 0.031	3.504ProIle: 3.504 ± 0.047	2.589ProLys: 2.589 ± 0.055	5.354ProLeu: 5.354 ± 0.07	1.818ProMet: 1.818 ± 0.042	2.58ProAsn: 2.58 ± 0.041	4.491ProPro: 4.491 ± 0.102	2.435ProGln: 2.435 ± 0.046	3.5ProArg: 3.5 ± 0.059	3.66ProSer: 3.66 ± 0.048	4.487ProThr: 4.487 ± 0.063	4.311ProVal: 4.311 ± 0.06	0.865ProTrp: 0.865 ± 0.022	1.14ProTyr: 1.14 ± 0.026	0.0ProXaa: 0.0 ± 0.0
Gln	4.414GlnAla: 4.414 ± 0.066	0.341GlnCys: 0.341 ± 0.014	1.473GlnAsp: 1.473 ± 0.03	1.944GlnGlu: 1.944 ± 0.041	1.716GlnPhe: 1.716 ± 0.032	2.511GlnGly: 2.511 ± 0.036	0.861GlnHis: 0.861 ± 0.023	2.4GlnIle: 2.4 ± 0.038	1.319GlnLys: 1.319 ± 0.031	4.931GlnLeu: 4.931 ± 0.065	0.945GlnMet: 0.945 ± 0.022	1.153GlnAsn: 1.153 ± 0.023	2.912GlnPro: 2.912 ± 0.053	2.22GlnGln: 2.22 ± 0.056	3.139GlnArg: 3.139 ± 0.053	3.034GlnSer: 3.034 ± 0.04	2.325GlnThr: 2.325 ± 0.034	2.797GlnVal: 2.797 ± 0.035	0.683GlnTrp: 0.683 ± 0.02	0.852GlnTyr: 0.852 ± 0.023	0.0GlnXaa: 0.0 ± 0.0
Arg	5.517ArgAla: 5.517 ± 0.071	0.733ArgCys: 0.733 ± 0.022	3.937ArgAsp: 3.937 ± 0.058	4.421ArgGlu: 4.421 ± 0.065	3.107ArgPhe: 3.107 ± 0.042	4.386ArgGly: 4.386 ± 0.059	1.385ArgHis: 1.385 ± 0.033	4.448ArgIle: 4.448 ± 0.046	2.449ArgLys: 2.449 ± 0.046	8.195ArgLeu: 8.195 ± 0.093	1.967ArgMet: 1.967 ± 0.036	2.332ArgAsn: 2.332 ± 0.036	3.707ArgPro: 3.707 ± 0.055	3.122ArgGln: 3.122 ± 0.05	5.049ArgArg: 5.049 ± 0.07	4.235ArgSer: 4.235 ± 0.055	3.702ArgThr: 3.702 ± 0.049	4.791ArgVal: 4.791 ± 0.044	1.434ArgTrp: 1.434 ± 0.033	1.908ArgTyr: 1.908 ± 0.036	0.0ArgXaa: 0.0 ± 0.0
Ser	5.71SerAla: 5.71 ± 0.066	0.49SerCys: 0.49 ± 0.019	3.341SerAsp: 3.341 ± 0.044	3.487SerGlu: 3.487 ± 0.058	2.107SerPhe: 2.107 ± 0.036	5.721SerGly: 5.721 ± 0.16	1.173SerHis: 1.173 ± 0.023	3.175SerIle: 3.175 ± 0.049	1.965SerLys: 1.965 ± 0.035	6.205SerLeu: 6.205 ± 0.067	1.507SerMet: 1.507 ± 0.03	1.98SerAsn: 1.98 ± 0.048	4.244SerPro: 4.244 ± 0.06	2.519SerGln: 2.519 ± 0.037	3.834SerArg: 3.834 ± 0.054	3.571SerSer: 3.571 ± 0.072	3.331SerThr: 3.331 ± 0.069	4.204SerVal: 4.204 ± 0.062	0.92SerTrp: 0.92 ± 0.025	1.157SerTyr: 1.157 ± 0.029	0.0SerXaa: 0.0 ± 0.0
Thr	5.698ThrAla: 5.698 ± 0.085	0.47ThrCys: 0.47 ± 0.019	3.088ThrAsp: 3.088 ± 0.046	2.833ThrGlu: 2.833 ± 0.043	1.955ThrPhe: 1.955 ± 0.038	5.403ThrGly: 5.403 ± 0.153	1.146ThrHis: 1.146 ± 0.025	3.56ThrIle: 3.56 ± 0.075	1.702ThrLys: 1.702 ± 0.035	6.382ThrLeu: 6.382 ± 0.079	1.141ThrMet: 1.141 ± 0.024	1.848ThrAsn: 1.848 ± 0.051	4.665ThrPro: 4.665 ± 0.068	2.113ThrGln: 2.113 ± 0.036	3.385ThrArg: 3.385 ± 0.048	3.112ThrSer: 3.112 ± 0.065	3.625ThrThr: 3.625 ± 0.087	4.406ThrVal: 4.406 ± 0.089	0.892ThrTrp: 0.892 ± 0.026	1.215ThrTyr: 1.215 ± 0.032	0.0ThrXaa: 0.0 ± 0.0
Val	6.878ValAla: 6.878 ± 0.07	0.714ValCys: 0.714 ± 0.024	3.688ValAsp: 3.688 ± 0.052	4.011ValGlu: 4.011 ± 0.047	2.265ValPhe: 2.265 ± 0.038	5.295ValGly: 5.295 ± 0.076	1.261ValHis: 1.261 ± 0.03	3.654ValIle: 3.654 ± 0.051	2.154ValLys: 2.154 ± 0.04	6.555ValLeu: 6.555 ± 0.071	1.578ValMet: 1.578 ± 0.035	2.199ValAsn: 2.199 ± 0.055	4.06ValPro: 4.06 ± 0.048	2.742ValGln: 2.742 ± 0.041	4.906ValArg: 4.906 ± 0.054	4.034ValSer: 4.034 ± 0.066	4.426ValThr: 4.426 ± 0.105	5.109ValVal: 5.109 ± 0.058	1.053ValTrp: 1.053 ± 0.022	1.55ValTyr: 1.55 ± 0.034	0.0ValXaa: 0.0 ± 0.0
Trp	1.267TrpAla: 1.267 ± 0.029	0.189TrpCys: 0.189 ± 0.01	0.864TrpAsp: 0.864 ± 0.026	0.83TrpGlu: 0.83 ± 0.025	0.611TrpPhe: 0.611 ± 0.019	1.023TrpGly: 1.023 ± 0.026	0.383TrpHis: 0.383 ± 0.013	0.924TrpIle: 0.924 ± 0.023	0.66TrpLys: 0.66 ± 0.019	2.11TrpLeu: 2.11 ± 0.043	0.523TrpMet: 0.523 ± 0.017	0.691TrpAsn: 0.691 ± 0.023	0.746TrpPro: 0.746 ± 0.025	0.875TrpGln: 0.875 ± 0.022	1.075TrpArg: 1.075 ± 0.026	0.921TrpSer: 0.921 ± 0.027	0.895TrpThr: 0.895 ± 0.025	1.119TrpVal: 1.119 ± 0.024	0.282TrpTrp: 0.282 ± 0.013	0.376TrpTyr: 0.376 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.049TyrAla: 2.049 ± 0.038	0.276TyrCys: 0.276 ± 0.014	1.24TyrAsp: 1.24 ± 0.03	1.179TyrGlu: 1.179 ± 0.028	0.934TyrPhe: 0.934 ± 0.024	1.785TyrGly: 1.785 ± 0.037	0.624TyrHis: 0.624 ± 0.02	0.736TyrIle: 0.736 ± 0.024	0.447TyrLys: 0.447 ± 0.017	2.542TyrLeu: 2.542 ± 0.038	0.279TyrMet: 0.279 ± 0.013	0.599TyrAsn: 0.599 ± 0.018	1.28TyrPro: 1.28 ± 0.031	1.047TyrGln: 1.047 ± 0.025	2.176TyrArg: 2.176 ± 0.035	1.295TyrSer: 1.295 ± 0.029	1.136TyrThr: 1.136 ± 0.034	1.396TyrVal: 1.396 ± 0.025	0.37TyrTrp: 0.37 ± 0.014	0.586TyrTyr: 0.586 ± 0.021	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5223 proteins (1989792 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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