Amino acid dipepetide frequency for Truepera radiovictrix (strain DSM 17093 / CIP 108686 / LMG 22925 / RQ-24)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	19.206AlaAla: 19.206 ± 0.219	1.001AlaCys: 1.001 ± 0.032	5.163AlaAsp: 5.163 ± 0.072	8.774AlaGlu: 8.774 ± 0.128	5.175AlaPhe: 5.175 ± 0.085	10.507AlaGly: 10.507 ± 0.113	2.877AlaHis: 2.877 ± 0.067	3.51AlaIle: 3.51 ± 0.07	2.752AlaLys: 2.752 ± 0.071	20.378AlaLeu: 20.378 ± 0.187	2.187AlaMet: 2.187 ± 0.053	1.942AlaAsn: 1.942 ± 0.054	7.596AlaPro: 7.596 ± 0.121	4.949AlaGln: 4.949 ± 0.086	11.201AlaArg: 11.201 ± 0.161	5.753AlaSer: 5.753 ± 0.085	5.959AlaThr: 5.959 ± 0.085	9.346AlaVal: 9.346 ± 0.115	1.986AlaTrp: 1.986 ± 0.049	3.182AlaTyr: 3.182 ± 0.072	0.0AlaXaa: 0.0 ± 0.0
Cys	0.912CysAla: 0.912 ± 0.04	0.085CysCys: 0.085 ± 0.01	0.398CysAsp: 0.398 ± 0.018	0.398CysGlu: 0.398 ± 0.02	0.191CysPhe: 0.191 ± 0.014	0.735CysGly: 0.735 ± 0.027	0.156CysHis: 0.156 ± 0.013	0.186CysIle: 0.186 ± 0.017	0.114CysLys: 0.114 ± 0.011	0.631CysLeu: 0.631 ± 0.029	0.069CysMet: 0.069 ± 0.009	0.162CysAsn: 0.162 ± 0.014	0.39CysPro: 0.39 ± 0.022	0.144CysGln: 0.144 ± 0.013	0.457CysArg: 0.457 ± 0.023	0.343CysSer: 0.343 ± 0.018	0.411CysThr: 0.411 ± 0.022	0.479CysVal: 0.479 ± 0.022	0.078CysTrp: 0.078 ± 0.01	0.179CysTyr: 0.179 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	6.834AspAla: 6.834 ± 0.083	0.19AspCys: 0.19 ± 0.014	2.495AspAsp: 2.495 ± 0.075	3.559AspGlu: 3.559 ± 0.071	1.869AspPhe: 1.869 ± 0.049	3.667AspGly: 3.667 ± 0.066	0.831AspHis: 0.831 ± 0.031	1.606AspIle: 1.606 ± 0.046	0.995AspLys: 0.995 ± 0.036	5.728AspLeu: 5.728 ± 0.079	0.613AspMet: 0.613 ± 0.028	0.95AspAsn: 0.95 ± 0.037	3.784AspPro: 3.784 ± 0.072	0.849AspGln: 0.849 ± 0.029	2.718AspArg: 2.718 ± 0.058	1.176AspSer: 1.176 ± 0.04	2.485AspThr: 2.485 ± 0.047	3.728AspVal: 3.728 ± 0.061	0.626AspTrp: 0.626 ± 0.03	1.222AspTyr: 1.222 ± 0.038	0.0AspXaa: 0.0 ± 0.0
Glu	11.069GluAla: 11.069 ± 0.142	0.2GluCys: 0.2 ± 0.015	2.624GluAsp: 2.624 ± 0.055	3.546GluGlu: 3.546 ± 0.079	1.37GluPhe: 1.37 ± 0.042	6.054GluGly: 6.054 ± 0.104	1.447GluHis: 1.447 ± 0.035	2.138GluIle: 2.138 ± 0.058	1.183GluLys: 1.183 ± 0.042	8.175GluLeu: 8.175 ± 0.116	1.015GluMet: 1.015 ± 0.038	1.275GluAsn: 1.275 ± 0.037	3.315GluPro: 3.315 ± 0.064	1.669GluGln: 1.669 ± 0.045	7.526GluArg: 7.526 ± 0.108	2.293GluSer: 2.293 ± 0.054	3.477GluThr: 3.477 ± 0.074	6.426GluVal: 6.426 ± 0.077	0.523GluTrp: 0.523 ± 0.021	0.907GluTyr: 0.907 ± 0.036	0.0GluXaa: 0.0 ± 0.0
Phe	4.499PheAla: 4.499 ± 0.087	0.305PheCys: 0.305 ± 0.019	2.225PheAsp: 2.225 ± 0.047	2.542PheGlu: 2.542 ± 0.063	1.581PhePhe: 1.581 ± 0.05	3.704PheGly: 3.704 ± 0.068	0.68PheHis: 0.68 ± 0.03	1.386PheIle: 1.386 ± 0.039	0.75PheLys: 0.75 ± 0.029	3.539PheLeu: 3.539 ± 0.086	0.638PheMet: 0.638 ± 0.03	0.91PheAsn: 0.91 ± 0.028	1.693PhePro: 1.693 ± 0.043	0.85PheGln: 0.85 ± 0.031	2.419PheArg: 2.419 ± 0.06	2.116PheSer: 2.116 ± 0.049	1.97PheThr: 1.97 ± 0.05	3.265PheVal: 3.265 ± 0.059	0.667PheTrp: 0.667 ± 0.027	1.221PheTyr: 1.221 ± 0.037	0.0PheXaa: 0.0 ± 0.0
Gly	12.005GlyAla: 12.005 ± 0.172	0.705GlyCys: 0.705 ± 0.028	4.374GlyAsp: 4.374 ± 0.073	6.093GlyGlu: 6.093 ± 0.095	3.661GlyPhe: 3.661 ± 0.06	8.169GlyGly: 8.169 ± 0.113	1.599GlyHis: 1.599 ± 0.043	2.795GlyIle: 2.795 ± 0.068	2.05GlyLys: 2.05 ± 0.049	9.947GlyLeu: 9.947 ± 0.135	1.588GlyMet: 1.588 ± 0.049	1.615GlyAsn: 1.615 ± 0.039	3.483GlyPro: 3.483 ± 0.069	2.297GlyGln: 2.297 ± 0.049	6.922GlyArg: 6.922 ± 0.089	4.113GlySer: 4.113 ± 0.062	4.511GlyThr: 4.511 ± 0.074	8.674GlyVal: 8.674 ± 0.107	1.313GlyTrp: 1.313 ± 0.04	2.382GlyTyr: 2.382 ± 0.046	0.0GlyXaa: 0.0 ± 0.0
His	2.578HisAla: 2.578 ± 0.056	0.142HisCys: 0.142 ± 0.012	1.026HisAsp: 1.026 ± 0.033	1.122HisGlu: 1.122 ± 0.042	0.766HisPhe: 0.766 ± 0.026	1.684HisGly: 1.684 ± 0.042	0.592HisHis: 0.592 ± 0.033	0.611HisIle: 0.611 ± 0.031	0.473HisLys: 0.473 ± 0.025	2.674HisLeu: 2.674 ± 0.048	0.243HisMet: 0.243 ± 0.019	0.475HisAsn: 0.475 ± 0.021	1.832HisPro: 1.832 ± 0.046	0.52HisGln: 0.52 ± 0.026	1.425HisArg: 1.425 ± 0.038	0.655HisSer: 0.655 ± 0.033	1.087HisThr: 1.087 ± 0.038	1.48HisVal: 1.48 ± 0.038	0.228HisTrp: 0.228 ± 0.014	0.591HisTyr: 0.591 ± 0.022	0.0HisXaa: 0.0 ± 0.0
Ile	4.132IleAla: 4.132 ± 0.064	0.235IleCys: 0.235 ± 0.016	1.811IleAsp: 1.811 ± 0.049	1.865IleGlu: 1.865 ± 0.052	1.244IlePhe: 1.244 ± 0.048	3.138IleGly: 3.138 ± 0.07	0.571IleHis: 0.571 ± 0.024	1.392IleIle: 1.392 ± 0.048	0.715IleLys: 0.715 ± 0.029	3.268IleLeu: 3.268 ± 0.067	0.485IleMet: 0.485 ± 0.025	0.874IleAsn: 0.874 ± 0.032	1.781IlePro: 1.781 ± 0.049	0.779IleGln: 0.779 ± 0.029	1.979IleArg: 1.979 ± 0.049	1.609IleSer: 1.609 ± 0.039	2.035IleThr: 2.035 ± 0.039	2.705IleVal: 2.705 ± 0.066	0.345IleTrp: 0.345 ± 0.018	0.855IleTyr: 0.855 ± 0.032	0.0IleXaa: 0.0 ± 0.0
Lys	2.498LysAla: 2.498 ± 0.065	0.085LysCys: 0.085 ± 0.009	1.016LysAsp: 1.016 ± 0.044	1.292LysGlu: 1.292 ± 0.043	0.447LysPhe: 0.447 ± 0.023	2.008LysGly: 2.008 ± 0.045	0.496LysHis: 0.496 ± 0.026	0.661LysIle: 0.661 ± 0.027	0.637LysLys: 0.637 ± 0.032	2.666LysLeu: 2.666 ± 0.065	0.371LysMet: 0.371 ± 0.018	0.498LysAsn: 0.498 ± 0.028	1.283LysPro: 1.283 ± 0.036	0.585LysGln: 0.585 ± 0.03	2.294LysArg: 2.294 ± 0.05	0.913LysSer: 0.913 ± 0.026	1.407LysThr: 1.407 ± 0.048	1.728LysVal: 1.728 ± 0.053	0.206LysTrp: 0.206 ± 0.017	0.42LysTyr: 0.42 ± 0.021	0.0LysXaa: 0.0 ± 0.0
Leu	16.532LeuAla: 16.532 ± 0.177	0.837LeuCys: 0.837 ± 0.03	5.036LeuAsp: 5.036 ± 0.08	9.994LeuGlu: 9.994 ± 0.119	4.362LeuPhe: 4.362 ± 0.079	11.346LeuGly: 11.346 ± 0.153	2.269LeuHis: 2.269 ± 0.058	4.2LeuIle: 4.2 ± 0.085	2.912LeuLys: 2.912 ± 0.074	14.539LeuLeu: 14.539 ± 0.214	1.879LeuMet: 1.879 ± 0.047	2.295LeuAsn: 2.295 ± 0.052	7.235LeuPro: 7.235 ± 0.09	3.719LeuGln: 3.719 ± 0.068	9.375LeuArg: 9.375 ± 0.113	7.247LeuSer: 7.247 ± 0.112	6.849LeuThr: 6.849 ± 0.112	8.88LeuVal: 8.88 ± 0.097	1.646LeuTrp: 1.646 ± 0.047	3.056LeuTyr: 3.056 ± 0.065	0.0LeuXaa: 0.0 ± 0.0
Met	1.836MetAla: 1.836 ± 0.049	0.092MetCys: 0.092 ± 0.01	0.68MetAsp: 0.68 ± 0.021	0.612MetGlu: 0.612 ± 0.025	0.47MetPhe: 0.47 ± 0.024	1.295MetGly: 1.295 ± 0.038	0.32MetHis: 0.32 ± 0.016	0.683MetIle: 0.683 ± 0.026	0.572MetLys: 0.572 ± 0.025	1.799MetLeu: 1.799 ± 0.041	0.339MetMet: 0.339 ± 0.02	0.533MetAsn: 0.533 ± 0.028	0.842MetPro: 0.842 ± 0.041	0.572MetGln: 0.572 ± 0.02	1.355MetArg: 1.355 ± 0.036	1.091MetSer: 1.091 ± 0.041	1.334MetThr: 1.334 ± 0.041	1.216MetVal: 1.216 ± 0.04	0.141MetTrp: 0.141 ± 0.01	0.309MetTyr: 0.309 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	2.539AsnAla: 2.539 ± 0.06	0.129AsnCys: 0.129 ± 0.011	0.916AsnAsp: 0.916 ± 0.036	0.936AsnGlu: 0.936 ± 0.036	0.798AsnPhe: 0.798 ± 0.034	1.476AsnGly: 1.476 ± 0.039	0.364AsnHis: 0.364 ± 0.018	0.804AsnIle: 0.804 ± 0.029	0.388AsnLys: 0.388 ± 0.022	2.776AsnLeu: 2.776 ± 0.057	0.299AsnMet: 0.299 ± 0.018	0.505AsnAsn: 0.505 ± 0.025	1.838AsnPro: 1.838 ± 0.046	0.522AsnGln: 0.522 ± 0.024	1.488AsnArg: 1.488 ± 0.044	0.694AsnSer: 0.694 ± 0.024	1.094AsnThr: 1.094 ± 0.042	1.826AsnVal: 1.826 ± 0.054	0.32AsnTrp: 0.32 ± 0.014	0.558AsnTyr: 0.558 ± 0.027	0.0AsnXaa: 0.0 ± 0.0
Pro	6.145ProAla: 6.145 ± 0.091	0.29ProCys: 0.29 ± 0.024	3.234ProAsp: 3.234 ± 0.072	5.846ProGlu: 5.846 ± 0.091	2.247ProPhe: 2.247 ± 0.055	4.552ProGly: 4.552 ± 0.071	1.426ProHis: 1.426 ± 0.042	1.649ProIle: 1.649 ± 0.055	1.507ProLys: 1.507 ± 0.043	6.867ProLeu: 6.867 ± 0.104	1.03ProMet: 1.03 ± 0.033	1.357ProAsn: 1.357 ± 0.036	3.98ProPro: 3.98 ± 0.109	2.037ProGln: 2.037 ± 0.052	3.678ProArg: 3.678 ± 0.062	2.983ProSer: 2.983 ± 0.064	3.24ProThr: 3.24 ± 0.073	4.081ProVal: 4.081 ± 0.062	0.858ProTrp: 0.858 ± 0.03	1.579ProTyr: 1.579 ± 0.044	0.0ProXaa: 0.0 ± 0.0
Gln	3.622GlnAla: 3.622 ± 0.064	0.104GlnCys: 0.104 ± 0.01	1.224GlnAsp: 1.224 ± 0.041	1.971GlnGlu: 1.971 ± 0.041	0.73GlnPhe: 0.73 ± 0.033	2.867GlnGly: 2.867 ± 0.051	0.657GlnHis: 0.657 ± 0.026	0.954GlnIle: 0.954 ± 0.034	0.629GlnLys: 0.629 ± 0.027	3.528GlnLeu: 3.528 ± 0.053	0.509GlnMet: 0.509 ± 0.024	0.746GlnAsn: 0.746 ± 0.03	1.588GlnPro: 1.588 ± 0.042	0.994GlnGln: 0.994 ± 0.032	3.025GlnArg: 3.025 ± 0.058	1.261GlnSer: 1.261 ± 0.031	1.704GlnThr: 1.704 ± 0.031	2.17GlnVal: 2.17 ± 0.049	0.27GlnTrp: 0.27 ± 0.016	0.489GlnTyr: 0.489 ± 0.021	0.0GlnXaa: 0.0 ± 0.0
Arg	11.529ArgAla: 11.529 ± 0.141	0.564ArgCys: 0.564 ± 0.031	3.84ArgAsp: 3.84 ± 0.072	5.617ArgGlu: 5.617 ± 0.093	3.503ArgPhe: 3.503 ± 0.062	6.445ArgGly: 6.445 ± 0.096	1.494ArgHis: 1.494 ± 0.044	2.291ArgIle: 2.291 ± 0.056	1.496ArgLys: 1.496 ± 0.037	9.474ArgLeu: 9.474 ± 0.121	1.338ArgMet: 1.338 ± 0.043	1.498ArgAsn: 1.498 ± 0.042	4.084ArgPro: 4.084 ± 0.073	2.057ArgGln: 2.057 ± 0.054	6.798ArgArg: 6.798 ± 0.078	3.641ArgSer: 3.641 ± 0.063	3.928ArgThr: 3.928 ± 0.051	6.801ArgVal: 6.801 ± 0.086	1.153ArgTrp: 1.153 ± 0.035	2.651ArgTyr: 2.651 ± 0.047	0.0ArgXaa: 0.0 ± 0.0
Ser	6.278SerAla: 6.278 ± 0.092	0.341SerCys: 0.341 ± 0.02	2.203SerAsp: 2.203 ± 0.051	2.853SerGlu: 2.853 ± 0.065	1.94SerPhe: 1.94 ± 0.047	5.036SerGly: 5.036 ± 0.081	0.848SerHis: 0.848 ± 0.031	1.239SerIle: 1.239 ± 0.042	0.976SerLys: 0.976 ± 0.031	5.336SerLeu: 5.336 ± 0.087	0.692SerMet: 0.692 ± 0.027	0.886SerAsn: 0.886 ± 0.03	2.855SerPro: 2.855 ± 0.063	1.288SerGln: 1.288 ± 0.044	3.253SerArg: 3.253 ± 0.059	2.453SerSer: 2.453 ± 0.062	2.202SerThr: 2.202 ± 0.046	4.017SerVal: 4.017 ± 0.067	0.738SerTrp: 0.738 ± 0.03	1.343SerTyr: 1.343 ± 0.043	0.0SerXaa: 0.0 ± 0.0
Thr	5.695ThrAla: 5.695 ± 0.084	0.355ThrCys: 0.355 ± 0.018	2.515ThrAsp: 2.515 ± 0.059	2.845ThrGlu: 2.845 ± 0.054	2.333ThrPhe: 2.333 ± 0.05	4.81ThrGly: 4.81 ± 0.077	1.231ThrHis: 1.231 ± 0.029	1.59ThrIle: 1.59 ± 0.051	1.023ThrLys: 1.023 ± 0.032	8.383ThrLeu: 8.383 ± 0.114	0.763ThrMet: 0.763 ± 0.026	1.009ThrAsn: 1.009 ± 0.041	4.401ThrPro: 4.401 ± 0.062	1.628ThrGln: 1.628 ± 0.041	3.595ThrArg: 3.595 ± 0.059	2.389ThrSer: 2.389 ± 0.049	2.704ThrThr: 2.704 ± 0.056	4.626ThrVal: 4.626 ± 0.088	0.725ThrTrp: 0.725 ± 0.026	1.401ThrTyr: 1.401 ± 0.043	0.0ThrXaa: 0.0 ± 0.0
Val	10.869ValAla: 10.869 ± 0.123	0.602ValCys: 0.602 ± 0.026	3.26ValAsp: 3.26 ± 0.067	4.123ValGlu: 4.123 ± 0.081	2.936ValPhe: 2.936 ± 0.064	7.068ValGly: 7.068 ± 0.095	1.489ValHis: 1.489 ± 0.042	3.1ValIle: 3.1 ± 0.07	1.636ValLys: 1.636 ± 0.041	9.428ValLeu: 9.428 ± 0.114	1.518ValMet: 1.518 ± 0.036	1.767ValAsn: 1.767 ± 0.045	4.447ValPro: 4.447 ± 0.069	2.421ValGln: 2.421 ± 0.05	6.876ValArg: 6.876 ± 0.095	4.32ValSer: 4.32 ± 0.077	5.317ValThr: 5.317 ± 0.082	6.8ValVal: 6.8 ± 0.095	1.101ValTrp: 1.101 ± 0.032	1.997ValTyr: 1.997 ± 0.053	0.0ValXaa: 0.0 ± 0.0
Trp	1.403TrpAla: 1.403 ± 0.04	0.091TrpCys: 0.091 ± 0.01	0.577TrpAsp: 0.577 ± 0.024	0.836TrpGlu: 0.836 ± 0.032	0.491TrpPhe: 0.491 ± 0.02	1.186TrpGly: 1.186 ± 0.035	0.331TrpHis: 0.331 ± 0.019	0.366TrpIle: 0.366 ± 0.018	0.193TrpLys: 0.193 ± 0.016	1.911TrpLeu: 1.911 ± 0.047	0.209TrpMet: 0.209 ± 0.014	0.346TrpAsn: 0.346 ± 0.019	0.682TrpPro: 0.682 ± 0.029	0.519TrpGln: 0.519 ± 0.024	1.385TrpArg: 1.385 ± 0.038	0.679TrpSer: 0.679 ± 0.027	0.7TrpThr: 0.7 ± 0.029	1.071TrpVal: 1.071 ± 0.034	0.256TrpTrp: 0.256 ± 0.018	0.315TrpTyr: 0.315 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.262TyrAla: 3.262 ± 0.061	0.167TyrCys: 0.167 ± 0.011	1.306TyrAsp: 1.306 ± 0.033	1.41TyrGlu: 1.41 ± 0.035	0.847TyrPhe: 0.847 ± 0.031	2.548TyrGly: 2.548 ± 0.051	0.526TyrHis: 0.526 ± 0.026	0.658TyrIle: 0.658 ± 0.029	0.509TyrLys: 0.509 ± 0.029	3.162TyrLeu: 3.162 ± 0.067	0.309TyrMet: 0.309 ± 0.018	0.627TyrAsn: 0.627 ± 0.028	1.475TyrPro: 1.475 ± 0.039	0.642TyrGln: 0.642 ± 0.022	2.433TyrArg: 2.433 ± 0.055	1.048TyrSer: 1.048 ± 0.032	1.608TyrThr: 1.608 ± 0.044	1.754TyrVal: 1.754 ± 0.047	0.366TyrTrp: 0.366 ± 0.019	0.622TyrTyr: 0.622 ± 0.027	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2924 proteins (943825 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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