Haliaeetus albicilla (White-tailed sea-eagle) (Falco albicilla)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Sauropsida; Sauria; Archelosauria; Archosauria; Dinosauria;

Average proteome isoelectric point is 6.66

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 8357 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A091P8A8|A0A091P8A8_HALAL Homer protein 3 (Fragment) OS=Haliaeetus albicilla OX=8969 GN=N329_08507 PE=3 SV=1
VV1 pKa = 5.13TTGGVLDD8 pKa = 3.88SCTAAEE14 pKa = 4.31LQLDD18 pKa = 4.14SLQCMDD24 pKa = 3.32SHH26 pKa = 8.26KK27 pKa = 11.19GDD29 pKa = 3.6VSDD32 pKa = 4.62VLPKK36 pKa = 10.4QEE38 pKa = 4.33TQSSEE43 pKa = 4.0CQAASSDD50 pKa = 3.87AEE52 pKa = 4.28VLHH55 pKa = 5.83TARR58 pKa = 11.84GFLGHH63 pKa = 6.03STTPQVLSANALLTDD78 pKa = 3.51ATEE81 pKa = 4.77CEE83 pKa = 4.38VGLPDD88 pKa = 4.38TYY90 pKa = 11.28LSPTADD96 pKa = 3.12SCEE99 pKa = 4.3NISLAATDD107 pKa = 4.87KK108 pKa = 11.38GDD110 pKa = 3.78LPHH113 pKa = 7.51SIVYY117 pKa = 10.04QNEE120 pKa = 3.61EE121 pKa = 4.41GKK123 pKa = 9.57WVTDD127 pKa = 3.51LAYY130 pKa = 9.07YY131 pKa = 10.17TSFDD135 pKa = 3.77EE136 pKa = 4.71EE137 pKa = 3.89QDD139 pKa = 3.93LNLSEE144 pKa = 4.94DD145 pKa = 3.61DD146 pKa = 4.59KK147 pKa = 11.61INEE150 pKa = 4.01EE151 pKa = 4.77FITT154 pKa = 4.04

Molecular weight: 16.58 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A091PQB3|A0A091PQB3_HALAL Pleckstrin homology domain-containing family A member 7 (Fragment) OS=Haliaeetus albicilla OX=8969 GN=N329_10838 PE=4 SV=1
KKK2 pKa = 10.12RR3 pKa = 11.84QGKKK7 pKa = 8.85RR8 pKa = 11.84QGKKK12 pKa = 8.73RR13 pKa = 11.84QGKKK17 pKa = 8.73RR18 pKa = 11.84QGKKK22 pKa = 8.38RR23 pKa = 11.84QGKKK27 pKa = 8.32RR28 pKa = 11.84QGKKK32 pKa = 8.87RR33 pKa = 11.84QGKKK37 pKa = 8.52RR38 pKa = 11.84QGKKK42 pKa = 8.48RR43 pKa = 11.84QGKKK47 pKa = 8.71RR48 pKa = 11.84QGKKK52 pKa = 8.82RR53 pKa = 11.84QGKKK57 pKa = 9.22RR58 pKa = 11.84

Molecular weight: 6.43 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

8357

0

8357

3523919

31

5001

421.7

47.48

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.249 ± 0.024

2.242 ± 0.024

5.095 ± 0.021

7.208 ± 0.033

3.98 ± 0.019

5.7 ± 0.033

2.535 ± 0.012

5.154 ± 0.02

6.569 ± 0.028

9.699 ± 0.034

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.282 ± 0.012

4.287 ± 0.017

5.103 ± 0.031

4.681 ± 0.026

5.095 ± 0.019

8.162 ± 0.036

5.43 ± 0.018

6.291 ± 0.023

1.189 ± 0.009

3.042 ± 0.019
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski