Amino acid dipepetide frequency for Blackberry virus A

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.081AlaAla: 2.081 ± 1.993
0.832AlaCys: 0.832 ± 0.45
1.665AlaAsp: 1.665 ± 0.72
2.913AlaGlu: 2.913 ± 1.082
1.665AlaPhe: 1.665 ± 1.348
4.578AlaGly: 4.578 ± 1.245
1.665AlaHis: 1.665 ± 0.9
2.497AlaIle: 2.497 ± 2.047
4.578AlaLys: 4.578 ± 1.702
5.826AlaLeu: 5.826 ± 1.526
1.248AlaMet: 1.248 ± 0.675
2.913AlaAsn: 2.913 ± 1.791
3.745AlaPro: 3.745 ± 1.453
1.248AlaGln: 1.248 ± 1.354
4.578AlaArg: 4.578 ± 1.619
3.329AlaSer: 3.329 ± 1.44
3.745AlaThr: 3.745 ± 1.203
3.329AlaVal: 3.329 ± 1.44
0.0AlaTrp: 0.0 ± 0.0
3.745AlaTyr: 3.745 ± 1.82
0.0AlaXaa: 0.0 ± 0.0
Cys
1.665CysAla: 1.665 ± 0.618
0.0CysCys: 0.0 ± 0.0
1.665CysAsp: 1.665 ± 0.618
0.832CysGlu: 0.832 ± 0.768
1.248CysPhe: 1.248 ± 0.709
1.665CysGly: 1.665 ± 0.618
0.416CysHis: 0.416 ± 0.934
0.832CysIle: 0.832 ± 0.674
2.497CysLys: 2.497 ± 0.842
1.248CysLeu: 1.248 ± 0.811
0.416CysMet: 0.416 ± 0.225
1.248CysAsn: 1.248 ± 0.675
0.832CysPro: 0.832 ± 0.45
0.832CysGln: 0.832 ± 0.674
0.832CysArg: 0.832 ± 0.674
1.665CysSer: 1.665 ± 0.618
0.832CysThr: 0.832 ± 0.45
1.248CysVal: 1.248 ± 1.171
0.0CysTrp: 0.0 ± 0.0
1.248CysTyr: 1.248 ± 1.768
0.0CysXaa: 0.0 ± 0.0
Asp
3.745AspAla: 3.745 ± 1.502
0.416AspCys: 0.416 ± 0.801
3.329AspAsp: 3.329 ± 1.375
6.242AspGlu: 6.242 ± 2.881
2.913AspPhe: 2.913 ± 1.181
2.913AspGly: 2.913 ± 2.804
2.497AspHis: 2.497 ± 1.191
3.329AspIle: 3.329 ± 1.205
4.161AspLys: 4.161 ± 0.959
6.242AspLeu: 6.242 ± 1.526
0.832AspMet: 0.832 ± 0.845
0.832AspAsn: 0.832 ± 0.845
4.994AspPro: 4.994 ± 0.638
0.416AspGln: 0.416 ± 0.225
3.329AspArg: 3.329 ± 1.538
4.161AspSer: 4.161 ± 2.25
1.248AspThr: 1.248 ± 2.404
2.913AspVal: 2.913 ± 1.016
1.248AspTrp: 1.248 ± 0.757
2.081AspTyr: 2.081 ± 1.125
0.0AspXaa: 0.0 ± 0.0
Glu
4.994GluAla: 4.994 ± 1.232
0.416GluCys: 0.416 ± 0.225
3.329GluAsp: 3.329 ± 0.833
9.155GluGlu: 9.155 ± 2.082
5.826GluPhe: 5.826 ± 2.106
3.745GluGly: 3.745 ± 0.988
2.497GluHis: 2.497 ± 1.35
2.081GluIle: 2.081 ± 2.025
4.161GluLys: 4.161 ± 1.611
9.571GluLeu: 9.571 ± 1.842
2.081GluMet: 2.081 ± 1.304
1.665GluAsn: 1.665 ± 0.72
4.578GluPro: 4.578 ± 1.986
3.329GluGln: 3.329 ± 1.8
5.826GluArg: 5.826 ± 2.226
5.41GluSer: 5.41 ± 2.108
2.913GluThr: 2.913 ± 1.189
3.745GluVal: 3.745 ± 1.026
1.248GluTrp: 1.248 ± 0.675
2.081GluTyr: 2.081 ± 1.552
0.0GluXaa: 0.0 ± 0.0
Phe
2.497PheAla: 2.497 ± 1.419
1.665PheCys: 1.665 ± 1.024
4.994PheAsp: 4.994 ± 2.336
2.081PheGlu: 2.081 ± 0.843
0.832PhePhe: 0.832 ± 0.45
4.578PheGly: 4.578 ± 0.508
0.0PheHis: 0.0 ± 0.0
1.665PheIle: 1.665 ± 0.9
2.913PheLys: 2.913 ± 1.189
3.329PheLeu: 3.329 ± 1.417
0.832PheMet: 0.832 ± 1.602
2.081PheAsn: 2.081 ± 0.706
2.497PhePro: 2.497 ± 1.533
1.665PheGln: 1.665 ± 0.9
2.081PheArg: 2.081 ± 0.796
2.913PheSer: 2.913 ± 1.119
2.497PheThr: 2.497 ± 1.212
3.329PheVal: 3.329 ± 2.048
0.0PheTrp: 0.0 ± 0.0
0.416PheTyr: 0.416 ± 0.225
0.0PheXaa: 0.0 ± 0.0
Gly
5.41GlyAla: 5.41 ± 1.998
1.248GlyCys: 1.248 ± 0.606
3.329GlyAsp: 3.329 ± 0.778
5.826GlyGlu: 5.826 ± 0.603
3.329GlyPhe: 3.329 ± 2.048
2.081GlyGly: 2.081 ± 1.676
0.416GlyHis: 0.416 ± 0.225
3.329GlyIle: 3.329 ± 0.657
5.41GlyLys: 5.41 ± 1.491
6.242GlyLeu: 6.242 ± 1.161
0.416GlyMet: 0.416 ± 0.225
2.081GlyAsn: 2.081 ± 1.707
5.41GlyPro: 5.41 ± 1.385
2.081GlyGln: 2.081 ± 0.92
4.994GlyArg: 4.994 ± 2.857
4.161GlySer: 4.161 ± 2.055
3.329GlyThr: 3.329 ± 1.065
2.913GlyVal: 2.913 ± 2.386
1.248GlyTrp: 1.248 ± 0.675
2.497GlyTyr: 2.497 ± 1.35
0.0GlyXaa: 0.0 ± 0.0
His
2.497HisAla: 2.497 ± 1.35
2.081HisCys: 2.081 ± 0.92
0.832HisAsp: 0.832 ± 0.45
1.665HisGlu: 1.665 ± 0.9
0.832HisPhe: 0.832 ± 0.81
1.665HisGly: 1.665 ± 0.838
0.832HisHis: 0.832 ± 0.45
0.832HisIle: 0.832 ± 0.81
1.665HisLys: 1.665 ± 1.192
0.832HisLeu: 0.832 ± 0.45
0.416HisMet: 0.416 ± 0.801
1.248HisAsn: 1.248 ± 0.606
2.497HisPro: 2.497 ± 0.846
0.832HisGln: 0.832 ± 0.768
0.416HisArg: 0.416 ± 0.225
1.248HisSer: 1.248 ± 0.757
1.665HisThr: 1.665 ± 0.881
2.913HisVal: 2.913 ± 1.411
0.416HisTrp: 0.416 ± 0.225
0.832HisTyr: 0.832 ± 0.45
0.0HisXaa: 0.0 ± 0.0
Ile
2.913IleAla: 2.913 ± 2.32
0.832IleCys: 0.832 ± 0.674
3.745IleAsp: 3.745 ± 1.819
3.745IleGlu: 3.745 ± 0.979
1.665IlePhe: 1.665 ± 0.72
2.913IleGly: 2.913 ± 0.831
1.248IleHis: 1.248 ± 0.675
0.832IleIle: 0.832 ± 0.45
3.329IleLys: 3.329 ± 1.205
3.745IleLeu: 3.745 ± 1.483
1.665IleMet: 1.665 ± 0.9
2.497IleAsn: 2.497 ± 1.118
0.416IlePro: 0.416 ± 0.225
1.665IleGln: 1.665 ± 1.24
3.329IleArg: 3.329 ± 1.205
6.658IleSer: 6.658 ± 2.502
4.161IleThr: 4.161 ± 1.152
2.081IleVal: 2.081 ± 1.221
0.416IleTrp: 0.416 ± 0.225
2.081IleTyr: 2.081 ± 1.461
0.0IleXaa: 0.0 ± 0.0
Lys
4.161LysAla: 4.161 ± 2.115
0.832LysCys: 0.832 ± 0.45
4.161LysAsp: 4.161 ± 1.411
4.994LysGlu: 4.994 ± 1.22
2.913LysPhe: 2.913 ± 1.189
4.578LysGly: 4.578 ± 1.986
1.665LysHis: 1.665 ± 0.618
3.745LysIle: 3.745 ± 0.763
2.913LysLys: 2.913 ± 1.51
7.074LysLeu: 7.074 ± 1.18
3.745LysMet: 3.745 ± 0.988
4.578LysAsn: 4.578 ± 2.475
0.832LysPro: 0.832 ± 0.45
1.665LysGln: 1.665 ± 0.838
7.074LysArg: 7.074 ± 2.103
4.578LysSer: 4.578 ± 1.712
2.497LysThr: 2.497 ± 0.965
7.907LysVal: 7.907 ± 2.89
0.416LysTrp: 0.416 ± 0.225
1.665LysTyr: 1.665 ± 1.024
0.0LysXaa: 0.0 ± 0.0
Leu
3.745LeuAla: 3.745 ± 1.305
2.913LeuCys: 2.913 ± 1.93
6.242LeuAsp: 6.242 ± 2.017
8.739LeuGlu: 8.739 ± 4.031
5.826LeuPhe: 5.826 ± 1.822
6.658LeuGly: 6.658 ± 1.727
2.913LeuHis: 2.913 ± 1.411
4.578LeuIle: 4.578 ± 1.885
9.155LeuLys: 9.155 ± 2.342
9.571LeuLeu: 9.571 ± 2.962
2.913LeuMet: 2.913 ± 1.309
2.497LeuAsn: 2.497 ± 0.846
4.578LeuPro: 4.578 ± 1.859
1.665LeuGln: 1.665 ± 0.618
5.41LeuArg: 5.41 ± 0.568
7.907LeuSer: 7.907 ± 1.239
6.658LeuThr: 6.658 ± 1.855
6.658LeuVal: 6.658 ± 4.519
0.0LeuTrp: 0.0 ± 0.0
1.665LeuTyr: 1.665 ± 0.9
0.0LeuXaa: 0.0 ± 0.0
Met
1.248MetAla: 1.248 ± 0.606
0.832MetCys: 0.832 ± 0.768
2.081MetAsp: 2.081 ± 0.706
2.497MetGlu: 2.497 ± 1.046
1.248MetPhe: 1.248 ± 0.675
2.081MetGly: 2.081 ± 1.262
0.832MetHis: 0.832 ± 1.493
1.665MetIle: 1.665 ± 0.9
1.665MetLys: 1.665 ± 0.9
3.745MetLeu: 3.745 ± 0.783
1.248MetMet: 1.248 ± 0.675
1.665MetAsn: 1.665 ± 0.72
0.416MetPro: 0.416 ± 0.225
0.416MetGln: 0.416 ± 0.225
2.081MetArg: 2.081 ± 1.262
1.665MetSer: 1.665 ± 0.983
1.248MetThr: 1.248 ± 1.135
1.248MetVal: 1.248 ± 0.675
0.0MetTrp: 0.0 ± 0.0
0.416MetTyr: 0.416 ± 0.801
0.0MetXaa: 0.0 ± 0.0
Asn
2.081AsnAla: 2.081 ± 1.712
0.0AsnCys: 0.0 ± 0.0
1.665AsnAsp: 1.665 ± 0.9
3.329AsnGlu: 3.329 ± 1.205
0.416AsnPhe: 0.416 ± 0.225
3.745AsnGly: 3.745 ± 0.763
0.832AsnHis: 0.832 ± 0.45
2.497AsnIle: 2.497 ± 2.304
4.578AsnLys: 4.578 ± 2.142
6.242AsnLeu: 6.242 ± 1.467
1.248AsnMet: 1.248 ± 0.606
0.416AsnAsn: 0.416 ± 0.882
1.665AsnPro: 1.665 ± 0.9
1.665AsnGln: 1.665 ± 0.9
0.832AsnArg: 0.832 ± 0.45
2.913AsnSer: 2.913 ± 1.412
2.081AsnThr: 2.081 ± 1.547
2.497AsnVal: 2.497 ± 0.923
0.416AsnTrp: 0.416 ± 0.934
2.497AsnTyr: 2.497 ± 1.35
0.0AsnXaa: 0.0 ± 0.0
Pro
1.665ProAla: 1.665 ± 1.691
0.416ProCys: 0.416 ± 0.225
2.913ProAsp: 2.913 ± 1.016
4.161ProGlu: 4.161 ± 1.758
1.665ProPhe: 1.665 ± 0.848
2.913ProGly: 2.913 ± 0.781
1.665ProHis: 1.665 ± 0.9
4.578ProIle: 4.578 ± 1.709
2.913ProLys: 2.913 ± 2.073
4.578ProLeu: 4.578 ± 0.508
0.416ProMet: 0.416 ± 0.225
2.497ProAsn: 2.497 ± 1.35
1.665ProPro: 1.665 ± 0.72
0.832ProGln: 0.832 ± 0.768
2.913ProArg: 2.913 ± 1.119
1.665ProSer: 1.665 ± 0.769
2.497ProThr: 2.497 ± 1.35
2.081ProVal: 2.081 ± 0.843
0.416ProTrp: 0.416 ± 0.934
2.081ProTyr: 2.081 ± 1.125
0.0ProXaa: 0.0 ± 0.0
Gln
0.416GlnAla: 0.416 ± 0.225
2.081GlnCys: 2.081 ± 0.92
0.416GlnAsp: 0.416 ± 0.225
2.497GlnGlu: 2.497 ± 0.846
0.832GlnPhe: 0.832 ± 0.45
1.665GlnGly: 1.665 ± 0.9
0.832GlnHis: 0.832 ± 0.845
2.497GlnIle: 2.497 ± 1.35
3.329GlnLys: 3.329 ± 1.295
1.665GlnLeu: 1.665 ± 1.024
0.832GlnMet: 0.832 ± 0.768
0.416GlnAsn: 0.416 ± 0.225
0.832GlnPro: 0.832 ± 0.45
0.0GlnGln: 0.0 ± 0.0
1.248GlnArg: 1.248 ± 0.709
1.665GlnSer: 1.665 ± 1.24
2.913GlnThr: 2.913 ± 0.704
2.913GlnVal: 2.913 ± 2.334
0.0GlnTrp: 0.0 ± 0.0
0.832GlnTyr: 0.832 ± 0.81
0.0GlnXaa: 0.0 ± 0.0
Arg
3.329ArgAla: 3.329 ± 2.447
1.248ArgCys: 1.248 ± 1.135
3.329ArgAsp: 3.329 ± 1.236
4.161ArgGlu: 4.161 ± 1.144
2.081ArgPhe: 2.081 ± 0.91
3.745ArgGly: 3.745 ± 1.632
0.416ArgHis: 0.416 ± 0.225
1.248ArgIle: 1.248 ± 0.606
4.161ArgLys: 4.161 ± 1.972
7.907ArgLeu: 7.907 ± 1.95
1.665ArgMet: 1.665 ± 0.9
2.913ArgAsn: 2.913 ± 1.93
2.081ArgPro: 2.081 ± 1.125
2.081ArgGln: 2.081 ± 0.864
2.913ArgArg: 2.913 ± 1.821
3.329ArgSer: 3.329 ± 1.482
2.913ArgThr: 2.913 ± 1.082
6.242ArgVal: 6.242 ± 2.721
0.832ArgTrp: 0.832 ± 0.845
2.497ArgTyr: 2.497 ± 1.046
0.0ArgXaa: 0.0 ± 0.0
Ser
4.994SerAla: 4.994 ± 0.896
1.248SerCys: 1.248 ± 0.675
4.578SerAsp: 4.578 ± 1.805
4.578SerGlu: 4.578 ± 1.008
2.497SerPhe: 2.497 ± 1.515
5.826SerGly: 5.826 ± 0.747
1.665SerHis: 1.665 ± 0.9
3.745SerIle: 3.745 ± 1.405
5.826SerLys: 5.826 ± 2.747
4.578SerLeu: 4.578 ± 1.739
1.665SerMet: 1.665 ± 0.72
5.41SerAsn: 5.41 ± 2.822
1.665SerPro: 1.665 ± 0.838
2.081SerGln: 2.081 ± 0.843
2.913SerArg: 2.913 ± 1.51
4.161SerSer: 4.161 ± 1.593
3.329SerThr: 3.329 ± 1.317
3.745SerVal: 3.745 ± 3.115
0.832SerTrp: 0.832 ± 0.45
3.329SerTyr: 3.329 ± 1.187
0.0SerXaa: 0.0 ± 0.0
Thr
2.081ThrAla: 2.081 ± 1.125
0.832ThrCys: 0.832 ± 0.45
2.913ThrAsp: 2.913 ± 0.593
4.578ThrGlu: 4.578 ± 1.584
2.497ThrPhe: 2.497 ± 1.046
2.497ThrGly: 2.497 ± 1.212
1.665ThrHis: 1.665 ± 0.618
4.578ThrIle: 4.578 ± 1.008
3.329ThrLys: 3.329 ± 1.205
6.242ThrLeu: 6.242 ± 0.837
2.081ThrMet: 2.081 ± 0.667
2.913ThrAsn: 2.913 ± 2.494
2.081ThrPro: 2.081 ± 0.92
2.081ThrGln: 2.081 ± 0.843
2.913ThrArg: 2.913 ± 2.062
2.081ThrSer: 2.081 ± 1.489
1.665ThrThr: 1.665 ± 0.769
2.497ThrVal: 2.497 ± 1.212
0.416ThrTrp: 0.416 ± 0.225
2.081ThrTyr: 2.081 ± 0.843
0.0ThrXaa: 0.0 ± 0.0
Val
3.745ValAla: 3.745 ± 0.514
2.081ValCys: 2.081 ± 1.476
4.578ValAsp: 4.578 ± 3.702
4.578ValGlu: 4.578 ± 1.76
2.913ValPhe: 2.913 ± 0.593
5.41ValGly: 5.41 ± 1.922
2.497ValHis: 2.497 ± 1.72
4.161ValIle: 4.161 ± 1.152
3.745ValLys: 3.745 ± 1.23
5.826ValLeu: 5.826 ± 1.722
2.913ValMet: 2.913 ± 1.522
1.665ValAsn: 1.665 ± 0.9
1.665ValPro: 1.665 ± 0.769
1.665ValGln: 1.665 ± 1.024
2.913ValArg: 2.913 ± 1.863
4.578ValSer: 4.578 ± 1.221
1.665ValThr: 1.665 ± 0.881
4.578ValVal: 4.578 ± 1.254
0.832ValTrp: 0.832 ± 0.45
1.665ValTyr: 1.665 ± 1.835
0.0ValXaa: 0.0 ± 0.0
Trp
1.248TrpAla: 1.248 ± 0.811
0.416TrpCys: 0.416 ± 0.225
0.0TrpAsp: 0.0 ± 0.0
0.832TrpGlu: 0.832 ± 0.45
0.416TrpPhe: 0.416 ± 0.225
0.416TrpGly: 0.416 ± 0.934
0.416TrpHis: 0.416 ± 0.917
0.0TrpIle: 0.0 ± 0.0
0.832TrpLys: 0.832 ± 0.45
0.832TrpLeu: 0.832 ± 0.45
0.0TrpMet: 0.0 ± 0.0
0.832TrpAsn: 0.832 ± 0.45
0.832TrpPro: 0.832 ± 0.45
0.0TrpGln: 0.0 ± 0.0
0.416TrpArg: 0.416 ± 0.225
0.0TrpSer: 0.0 ± 0.0
1.248TrpThr: 1.248 ± 0.811
0.416TrpVal: 0.416 ± 0.225
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.665TyrAla: 1.665 ± 0.769
0.832TyrCys: 0.832 ± 0.845
2.081TyrAsp: 2.081 ± 0.706
1.665TyrGlu: 1.665 ± 0.769
1.248TyrPhe: 1.248 ± 0.675
2.081TyrGly: 2.081 ± 1.908
1.248TyrHis: 1.248 ± 0.675
1.248TyrIle: 1.248 ± 0.675
0.832TyrLys: 0.832 ± 0.45
4.994TyrLeu: 4.994 ± 1.569
1.248TyrMet: 1.248 ± 0.675
1.248TyrAsn: 1.248 ± 0.811
1.248TyrPro: 1.248 ± 1.135
1.665TyrGln: 1.665 ± 0.881
2.081TyrArg: 2.081 ± 0.706
4.578TyrSer: 4.578 ± 1.245
2.913TyrThr: 2.913 ± 1.575
0.416TyrVal: 0.416 ± 0.934
0.416TyrTrp: 0.416 ± 0.225
0.416TyrTyr: 0.416 ± 0.225
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (2404 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski