Amino acid dipepetide frequency for Campylobacter curvus (strain 525.92)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.718AlaAla: 6.718 ± 0.14
1.053AlaCys: 1.053 ± 0.049
4.009AlaAsp: 4.009 ± 0.076
3.343AlaGlu: 3.343 ± 0.093
3.854AlaPhe: 3.854 ± 0.099
5.361AlaGly: 5.361 ± 0.121
1.452AlaHis: 1.452 ± 0.05
6.195AlaIle: 6.195 ± 0.118
8.16AlaLys: 8.16 ± 0.136
9.313AlaLeu: 9.313 ± 0.14
2.402AlaMet: 2.402 ± 0.066
4.446AlaAsn: 4.446 ± 0.11
2.315AlaPro: 2.315 ± 0.063
3.235AlaGln: 3.235 ± 0.077
3.675AlaArg: 3.675 ± 0.078
5.325AlaSer: 5.325 ± 0.113
3.51AlaThr: 3.51 ± 0.095
5.252AlaVal: 5.252 ± 0.116
0.564AlaTrp: 0.564 ± 0.041
2.75AlaTyr: 2.75 ± 0.071
0.0AlaXaa: 0.0 ± 0.0
Cys
0.997CysAla: 0.997 ± 0.047
0.128CysCys: 0.128 ± 0.015
0.782CysAsp: 0.782 ± 0.036
1.171CysGlu: 1.171 ± 0.051
0.6CysPhe: 0.6 ± 0.032
1.033CysGly: 1.033 ± 0.052
0.269CysHis: 0.269 ± 0.033
0.764CysIle: 0.764 ± 0.042
0.762CysLys: 0.762 ± 0.038
0.876CysLeu: 0.876 ± 0.036
0.249CysMet: 0.249 ± 0.02
0.329CysAsn: 0.329 ± 0.024
0.394CysPro: 0.394 ± 0.027
0.239CysGln: 0.239 ± 0.023
0.297CysArg: 0.297 ± 0.022
0.627CysSer: 0.627 ± 0.034
0.435CysThr: 0.435 ± 0.026
0.997CysVal: 0.997 ± 0.041
0.07CysTrp: 0.07 ± 0.01
0.37CysTyr: 0.37 ± 0.021
0.0CysXaa: 0.0 ± 0.0
Asp
4.845AspAla: 4.845 ± 0.094
0.481AspCys: 0.481 ± 0.033
3.426AspAsp: 3.426 ± 0.101
6.12AspGlu: 6.12 ± 0.116
3.094AspPhe: 3.094 ± 0.082
3.83AspGly: 3.83 ± 0.09
0.67AspHis: 0.67 ± 0.032
4.921AspIle: 4.921 ± 0.111
4.855AspLys: 4.855 ± 0.094
4.429AspLeu: 4.429 ± 0.098
1.628AspMet: 1.628 ± 0.053
1.761AspAsn: 1.761 ± 0.068
1.526AspPro: 1.526 ± 0.053
0.929AspGln: 0.929 ± 0.037
1.901AspArg: 1.901 ± 0.062
2.671AspSer: 2.671 ± 0.071
2.801AspThr: 2.801 ± 0.097
3.876AspVal: 3.876 ± 0.076
0.348AspTrp: 0.348 ± 0.026
1.942AspTyr: 1.942 ± 0.068
0.0AspXaa: 0.0 ± 0.0
Glu
5.257GluAla: 5.257 ± 0.112
0.726GluCys: 0.726 ± 0.039
2.826GluAsp: 2.826 ± 0.072
3.462GluGlu: 3.462 ± 0.106
4.088GluPhe: 4.088 ± 0.079
3.391GluGly: 3.391 ± 0.078
1.137GluHis: 1.137 ± 0.044
6.938GluIle: 6.938 ± 0.139
4.962GluLys: 4.962 ± 0.114
7.599GluLeu: 7.599 ± 0.137
1.555GluMet: 1.555 ± 0.053
4.407GluAsn: 4.407 ± 0.085
2.046GluPro: 2.046 ± 0.063
2.446GluGln: 2.446 ± 0.071
3.213GluArg: 3.213 ± 0.08
3.099GluSer: 3.099 ± 0.08
2.167GluThr: 2.167 ± 0.065
3.699GluVal: 3.699 ± 0.085
0.476GluTrp: 0.476 ± 0.028
2.173GluTyr: 2.173 ± 0.057
0.0GluXaa: 0.0 ± 0.0
Phe
4.439PheAla: 4.439 ± 0.104
0.883PheCys: 0.883 ± 0.039
3.713PheAsp: 3.713 ± 0.09
3.81PheGlu: 3.81 ± 0.086
2.748PhePhe: 2.748 ± 0.092
4.229PheGly: 4.229 ± 0.096
0.687PheHis: 0.687 ± 0.032
4.35PheIle: 4.35 ± 0.103
4.361PheLys: 4.361 ± 0.107
5.199PheLeu: 5.199 ± 0.125
1.481PheMet: 1.481 ± 0.052
2.277PheAsn: 2.277 ± 0.062
1.009PhePro: 1.009 ± 0.042
0.835PheGln: 0.835 ± 0.039
1.642PheArg: 1.642 ± 0.052
4.258PheSer: 4.258 ± 0.085
2.342PheThr: 2.342 ± 0.062
3.532PheVal: 3.532 ± 0.098
0.542PheTrp: 0.542 ± 0.034
2.276PheTyr: 2.276 ± 0.061
0.0PheXaa: 0.0 ± 0.0
Gly
5.885GlyAla: 5.885 ± 0.116
0.951GlyCys: 0.951 ± 0.05
3.488GlyAsp: 3.488 ± 0.09
4.949GlyGlu: 4.949 ± 0.097
3.9GlyPhe: 3.9 ± 0.086
4.945GlyGly: 4.945 ± 0.135
1.096GlyHis: 1.096 ± 0.047
5.042GlyIle: 5.042 ± 0.1
5.155GlyLys: 5.155 ± 0.107
6.098GlyLeu: 6.098 ± 0.11
1.766GlyMet: 1.766 ± 0.059
2.329GlyAsn: 2.329 ± 0.087
0.888GlyPro: 0.888 ± 0.049
1.521GlyGln: 1.521 ± 0.052
2.567GlyArg: 2.567 ± 0.068
4.028GlySer: 4.028 ± 0.087
2.767GlyThr: 2.767 ± 0.088
5.808GlyVal: 5.808 ± 0.111
0.569GlyTrp: 0.569 ± 0.033
2.791GlyTyr: 2.791 ± 0.086
0.0GlyXaa: 0.0 ± 0.0
His
1.229HisAla: 1.229 ± 0.041
0.176HisCys: 0.176 ± 0.017
0.869HisAsp: 0.869 ± 0.041
1.086HisGlu: 1.086 ± 0.041
0.921HisPhe: 0.921 ± 0.046
1.117HisGly: 1.117 ± 0.051
0.341HisHis: 0.341 ± 0.026
1.403HisIle: 1.403 ± 0.052
1.125HisLys: 1.125 ± 0.048
1.403HisLeu: 1.403 ± 0.052
0.356HisMet: 0.356 ± 0.025
0.559HisAsn: 0.559 ± 0.03
0.762HisPro: 0.762 ± 0.037
0.407HisGln: 0.407 ± 0.027
0.523HisArg: 0.523 ± 0.033
0.944HisSer: 0.944 ± 0.043
0.784HisThr: 0.784 ± 0.033
0.871HisVal: 0.871 ± 0.04
0.136HisTrp: 0.136 ± 0.015
0.603HisTyr: 0.603 ± 0.029
0.0HisXaa: 0.0 ± 0.0
Ile
6.751IleAla: 6.751 ± 0.111
1.181IleCys: 1.181 ± 0.048
4.935IleAsp: 4.935 ± 0.104
4.899IleGlu: 4.899 ± 0.098
4.466IlePhe: 4.466 ± 0.098
5.247IleGly: 5.247 ± 0.096
0.98IleHis: 0.98 ± 0.044
5.073IleIle: 5.073 ± 0.121
6.718IleLys: 6.718 ± 0.127
8.298IleLeu: 8.298 ± 0.147
1.66IleMet: 1.66 ± 0.052
4.315IleAsn: 4.315 ± 0.091
2.109IlePro: 2.109 ± 0.07
1.461IleGln: 1.461 ± 0.053
2.492IleArg: 2.492 ± 0.077
6.019IleSer: 6.019 ± 0.123
3.481IleThr: 3.481 ± 0.077
5.554IleVal: 5.554 ± 0.104
0.54IleTrp: 0.54 ± 0.027
3.36IleTyr: 3.36 ± 0.076
0.0IleXaa: 0.0 ± 0.0
Lys
5.925LysAla: 5.925 ± 0.116
0.629LysCys: 0.629 ± 0.037
5.264LysAsp: 5.264 ± 0.122
6.398LysGlu: 6.398 ± 0.139
6.139LysPhe: 6.139 ± 0.124
4.33LysGly: 4.33 ± 0.092
1.055LysHis: 1.055 ± 0.04
7.888LysIle: 7.888 ± 0.154
6.197LysLys: 6.197 ± 0.119
5.895LysLeu: 5.895 ± 0.116
2.298LysMet: 2.298 ± 0.067
5.891LysAsn: 5.891 ± 0.105
2.497LysPro: 2.497 ± 0.076
2.501LysGln: 2.501 ± 0.077
3.513LysArg: 3.513 ± 0.086
4.865LysSer: 4.865 ± 0.1
3.8LysThr: 3.8 ± 0.089
3.79LysVal: 3.79 ± 0.089
0.508LysTrp: 0.508 ± 0.028
2.325LysTyr: 2.325 ± 0.072
0.0LysXaa: 0.0 ± 0.0
Leu
8.881LeuAla: 8.881 ± 0.145
1.25LeuCys: 1.25 ± 0.053
5.16LeuAsp: 5.16 ± 0.098
6.11LeuGlu: 6.11 ± 0.121
4.683LeuPhe: 4.683 ± 0.109
6.948LeuGly: 6.948 ± 0.124
1.423LeuHis: 1.423 ± 0.045
6.587LeuIle: 6.587 ± 0.119
9.197LeuLys: 9.197 ± 0.141
8.498LeuLeu: 8.498 ± 0.138
2.301LeuMet: 2.301 ± 0.062
6.161LeuAsn: 6.161 ± 0.11
3.328LeuPro: 3.328 ± 0.075
2.671LeuGln: 2.671 ± 0.07
3.737LeuArg: 3.737 ± 0.092
7.449LeuSer: 7.449 ± 0.12
3.936LeuThr: 3.936 ± 0.091
5.743LeuVal: 5.743 ± 0.113
0.638LeuTrp: 0.638 ± 0.034
2.97LeuTyr: 2.97 ± 0.082
0.0LeuXaa: 0.0 ± 0.0
Met
1.979MetAla: 1.979 ± 0.067
0.21MetCys: 0.21 ± 0.018
1.217MetAsp: 1.217 ± 0.044
0.907MetGlu: 0.907 ± 0.042
1.026MetPhe: 1.026 ± 0.048
1.616MetGly: 1.616 ± 0.06
0.382MetHis: 0.382 ± 0.024
2.073MetIle: 2.073 ± 0.065
2.17MetLys: 2.17 ± 0.066
2.68MetLeu: 2.68 ± 0.076
0.726MetMet: 0.726 ± 0.039
1.261MetAsn: 1.261 ± 0.044
1.135MetPro: 1.135 ± 0.043
1.234MetGln: 1.234 ± 0.046
1.277MetArg: 1.277 ± 0.049
2.107MetSer: 2.107 ± 0.059
1.019MetThr: 1.019 ± 0.043
1.309MetVal: 1.309 ± 0.05
0.141MetTrp: 0.141 ± 0.016
0.513MetTyr: 0.513 ± 0.032
0.0MetXaa: 0.0 ± 0.0
Asn
4.453AsnAla: 4.453 ± 0.103
0.332AsnCys: 0.332 ± 0.025
3.063AsnAsp: 3.063 ± 0.081
4.209AsnGlu: 4.209 ± 0.094
3.611AsnPhe: 3.611 ± 0.077
3.498AsnGly: 3.498 ± 0.077
0.694AsnHis: 0.694 ± 0.031
4.154AsnIle: 4.154 ± 0.092
3.295AsnLys: 3.295 ± 0.078
6.725AsnLeu: 6.725 ± 0.135
1.009AsnMet: 1.009 ± 0.043
1.749AsnAsn: 1.749 ± 0.076
1.785AsnPro: 1.785 ± 0.059
1.287AsnGln: 1.287 ± 0.051
1.623AsnArg: 1.623 ± 0.06
3.27AsnSer: 3.27 ± 0.08
2.122AsnThr: 2.122 ± 0.066
3.135AsnVal: 3.135 ± 0.08
0.223AsnTrp: 0.223 ± 0.022
1.539AsnTyr: 1.539 ± 0.057
0.0AsnXaa: 0.0 ± 0.0
Pro
2.001ProAla: 2.001 ± 0.066
0.305ProCys: 0.305 ± 0.026
1.541ProAsp: 1.541 ± 0.051
1.826ProGlu: 1.826 ± 0.059
1.74ProPhe: 1.74 ± 0.057
1.425ProGly: 1.425 ± 0.054
0.619ProHis: 0.619 ± 0.033
2.315ProIle: 2.315 ± 0.061
2.656ProLys: 2.656 ± 0.072
2.901ProLeu: 2.901 ± 0.074
0.735ProMet: 0.735 ± 0.034
1.758ProAsn: 1.758 ± 0.059
0.856ProPro: 0.856 ± 0.047
1.163ProGln: 1.163 ± 0.046
1.021ProArg: 1.021 ± 0.04
2.146ProSer: 2.146 ± 0.063
1.522ProThr: 1.522 ± 0.055
1.959ProVal: 1.959 ± 0.058
0.222ProTrp: 0.222 ± 0.018
1.253ProTyr: 1.253 ± 0.046
0.0ProXaa: 0.0 ± 0.0
Gln
2.114GlnAla: 2.114 ± 0.062
0.216GlnCys: 0.216 ± 0.017
1.398GlnAsp: 1.398 ± 0.05
1.64GlnGlu: 1.64 ± 0.059
0.849GlnPhe: 0.849 ± 0.038
1.625GlnGly: 1.625 ± 0.054
0.334GlnHis: 0.334 ± 0.025
3.167GlnIle: 3.167 ± 0.082
2.913GlnLys: 2.913 ± 0.081
2.051GlnLeu: 2.051 ± 0.069
0.844GlnMet: 0.844 ± 0.041
2.963GlnAsn: 2.963 ± 0.086
0.696GlnPro: 0.696 ± 0.033
0.66GlnGln: 0.66 ± 0.039
1.209GlnArg: 1.209 ± 0.048
2.122GlnSer: 2.122 ± 0.061
1.696GlnThr: 1.696 ± 0.053
1.377GlnVal: 1.377 ± 0.047
0.208GlnTrp: 0.208 ± 0.022
0.661GlnTyr: 0.661 ± 0.035
0.0GlnXaa: 0.0 ± 0.0
Arg
3.421ArgAla: 3.421 ± 0.092
0.402ArgCys: 0.402 ± 0.025
2.076ArgAsp: 2.076 ± 0.068
2.874ArgGlu: 2.874 ± 0.089
1.938ArgPhe: 1.938 ± 0.061
2.373ArgGly: 2.373 ± 0.065
0.711ArgHis: 0.711 ± 0.031
3.043ArgIle: 3.043 ± 0.075
2.443ArgLys: 2.443 ± 0.066
4.163ArgLeu: 4.163 ± 0.093
0.885ArgMet: 0.885 ± 0.045
1.802ArgAsn: 1.802 ± 0.057
1.149ArgPro: 1.149 ± 0.044
1.273ArgGln: 1.273 ± 0.046
1.659ArgArg: 1.659 ± 0.06
2.202ArgSer: 2.202 ± 0.061
1.541ArgThr: 1.541 ± 0.05
2.733ArgVal: 2.733 ± 0.079
0.274ArgTrp: 0.274 ± 0.023
1.718ArgTyr: 1.718 ± 0.063
0.0ArgXaa: 0.0 ± 0.0
Ser
5.428SerAla: 5.428 ± 0.099
0.687SerCys: 0.687 ± 0.038
3.675SerAsp: 3.675 ± 0.09
4.454SerGlu: 4.454 ± 0.084
3.406SerPhe: 3.406 ± 0.074
5.23SerGly: 5.23 ± 0.104
1.103SerHis: 1.103 ± 0.041
4.32SerIle: 4.32 ± 0.098
5.068SerLys: 5.068 ± 0.104
6.609SerLeu: 6.609 ± 0.118
1.476SerMet: 1.476 ± 0.054
2.804SerAsn: 2.804 ± 0.08
1.94SerPro: 1.94 ± 0.065
2.15SerGln: 2.15 ± 0.07
2.383SerArg: 2.383 ± 0.064
4.432SerSer: 4.432 ± 0.117
2.513SerThr: 2.513 ± 0.073
4.846SerVal: 4.846 ± 0.088
0.542SerTrp: 0.542 ± 0.03
2.451SerTyr: 2.451 ± 0.083
0.0SerXaa: 0.0 ± 0.0
Thr
3.595ThrAla: 3.595 ± 0.1
0.373ThrCys: 0.373 ± 0.029
2.393ThrAsp: 2.393 ± 0.079
1.543ThrGlu: 1.543 ± 0.055
1.809ThrPhe: 1.809 ± 0.057
3.029ThrGly: 3.029 ± 0.098
1.021ThrHis: 1.021 ± 0.044
3.454ThrIle: 3.454 ± 0.097
3.425ThrLys: 3.425 ± 0.078
4.737ThrLeu: 4.737 ± 0.093
0.994ThrMet: 0.994 ± 0.043
2.286ThrAsn: 2.286 ± 0.074
2.187ThrPro: 2.187 ± 0.068
1.717ThrGln: 1.717 ± 0.055
1.684ThrArg: 1.684 ± 0.059
3.053ThrSer: 3.053 ± 0.074
2.295ThrThr: 2.295 ± 0.098
1.819ThrVal: 1.819 ± 0.072
0.293ThrTrp: 0.293 ± 0.025
1.481ThrTyr: 1.481 ± 0.054
0.0ThrXaa: 0.0 ± 0.0
Val
5.492ValAla: 5.492 ± 0.123
0.98ValCys: 0.98 ± 0.044
3.3ValAsp: 3.3 ± 0.087
3.353ValGlu: 3.353 ± 0.083
3.331ValPhe: 3.331 ± 0.103
4.401ValGly: 4.401 ± 0.111
0.842ValHis: 0.842 ± 0.035
5.025ValIle: 5.025 ± 0.104
5.158ValLys: 5.158 ± 0.098
6.239ValLeu: 6.239 ± 0.114
1.65ValMet: 1.65 ± 0.057
2.932ValAsn: 2.932 ± 0.078
2.073ValPro: 2.073 ± 0.068
1.672ValGln: 1.672 ± 0.056
2.61ValArg: 2.61 ± 0.076
4.558ValSer: 4.558 ± 0.099
2.591ValThr: 2.591 ± 0.077
4.834ValVal: 4.834 ± 0.125
0.534ValTrp: 0.534 ± 0.034
1.948ValTyr: 1.948 ± 0.059
0.0ValXaa: 0.0 ± 0.0
Trp
0.609TrpAla: 0.609 ± 0.036
0.09TrpCys: 0.09 ± 0.013
0.44TrpAsp: 0.44 ± 0.028
0.349TrpGlu: 0.349 ± 0.028
0.384TrpPhe: 0.384 ± 0.027
0.569TrpGly: 0.569 ± 0.031
0.169TrpHis: 0.169 ± 0.017
0.539TrpIle: 0.539 ± 0.031
0.314TrpLys: 0.314 ± 0.025
0.919TrpLeu: 0.919 ± 0.043
0.218TrpMet: 0.218 ± 0.02
0.239TrpAsn: 0.239 ± 0.023
0.119TrpPro: 0.119 ± 0.014
0.368TrpGln: 0.368 ± 0.028
0.36TrpArg: 0.36 ± 0.028
0.394TrpSer: 0.394 ± 0.027
0.251TrpThr: 0.251 ± 0.023
0.462TrpVal: 0.462 ± 0.034
0.116TrpTrp: 0.116 ± 0.014
0.312TrpTyr: 0.312 ± 0.026
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.915TyrAla: 2.915 ± 0.078
0.334TyrCys: 0.334 ± 0.026
2.475TyrAsp: 2.475 ± 0.071
3.166TyrGlu: 3.166 ± 0.085
2.03TyrPhe: 2.03 ± 0.065
2.344TyrGly: 2.344 ± 0.065
0.631TyrHis: 0.631 ± 0.03
2.289TyrIle: 2.289 ± 0.07
2.774TyrLys: 2.774 ± 0.079
3.038TyrLeu: 3.038 ± 0.07
0.748TyrMet: 0.748 ± 0.038
1.509TyrAsn: 1.509 ± 0.059
1.151TyrPro: 1.151 ± 0.048
0.973TyrGln: 0.973 ± 0.042
1.296TyrArg: 1.296 ± 0.051
1.945TyrSer: 1.945 ± 0.059
1.616TyrThr: 1.616 ± 0.067
1.93TyrVal: 1.93 ± 0.059
0.274TyrTrp: 0.274 ± 0.025
1.229TyrTyr: 1.229 ± 0.053
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1860 proteins (586621 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski