Amino acid dipepetide frequency for Scylla serrata reovirus SZ-2007

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.541AlaAla: 4.541 ± 1.296
0.151AlaCys: 0.151 ± 0.145
2.573AlaAsp: 2.573 ± 0.599
3.935AlaGlu: 3.935 ± 0.573
3.33AlaPhe: 3.33 ± 0.503
3.935AlaGly: 3.935 ± 0.748
1.362AlaHis: 1.362 ± 0.309
5.6AlaIle: 5.6 ± 0.986
2.573AlaLys: 2.573 ± 0.708
4.995AlaLeu: 4.995 ± 0.834
1.059AlaMet: 1.059 ± 0.355
3.178AlaAsn: 3.178 ± 0.51
2.27AlaPro: 2.27 ± 0.87
2.422AlaGln: 2.422 ± 0.714
3.784AlaArg: 3.784 ± 0.637
6.206AlaSer: 6.206 ± 1.093
5.146AlaThr: 5.146 ± 1.26
5.751AlaVal: 5.751 ± 0.725
0.303AlaTrp: 0.303 ± 0.175
2.573AlaTyr: 2.573 ± 0.722
0.0AlaXaa: 0.0 ± 0.0
Cys
0.303CysAla: 0.303 ± 0.237
0.0CysCys: 0.0 ± 0.0
1.211CysAsp: 1.211 ± 0.564
0.303CysGlu: 0.303 ± 0.195
0.454CysPhe: 0.454 ± 0.232
0.454CysGly: 0.454 ± 0.257
0.454CysHis: 0.454 ± 0.327
0.454CysIle: 0.454 ± 0.279
0.303CysLys: 0.303 ± 0.193
0.605CysLeu: 0.605 ± 0.257
0.0CysMet: 0.0 ± 0.0
0.303CysAsn: 0.303 ± 0.194
0.605CysPro: 0.605 ± 0.382
0.454CysGln: 0.454 ± 0.192
0.605CysArg: 0.605 ± 0.285
0.605CysSer: 0.605 ± 0.319
1.211CysThr: 1.211 ± 0.478
0.454CysVal: 0.454 ± 0.272
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.6AspAla: 5.6 ± 0.388
0.908AspCys: 0.908 ± 0.369
4.087AspAsp: 4.087 ± 0.331
4.541AspGlu: 4.541 ± 0.413
1.665AspPhe: 1.665 ± 0.388
2.27AspGly: 2.27 ± 0.487
2.27AspHis: 2.27 ± 0.463
5.449AspIle: 5.449 ± 0.999
3.633AspLys: 3.633 ± 0.773
5.903AspLeu: 5.903 ± 0.532
1.514AspMet: 1.514 ± 0.38
1.968AspAsn: 1.968 ± 0.52
0.908AspPro: 0.908 ± 0.315
2.119AspGln: 2.119 ± 0.746
3.784AspArg: 3.784 ± 1.025
4.995AspSer: 4.995 ± 0.894
4.389AspThr: 4.389 ± 0.806
3.33AspVal: 3.33 ± 0.473
0.908AspTrp: 0.908 ± 0.437
3.027AspTyr: 3.027 ± 0.585
0.0AspXaa: 0.0 ± 0.0
Glu
2.876GluAla: 2.876 ± 0.501
0.454GluCys: 0.454 ± 0.262
3.178GluAsp: 3.178 ± 0.895
2.724GluGlu: 2.724 ± 0.505
2.422GluPhe: 2.422 ± 0.598
1.211GluGly: 1.211 ± 0.426
1.059GluHis: 1.059 ± 0.461
4.541GluIle: 4.541 ± 1.047
3.633GluLys: 3.633 ± 0.652
4.541GluLeu: 4.541 ± 0.729
1.968GluMet: 1.968 ± 0.446
1.362GluAsn: 1.362 ± 0.547
2.119GluPro: 2.119 ± 0.436
3.633GluGln: 3.633 ± 0.489
4.087GluArg: 4.087 ± 0.57
4.541GluSer: 4.541 ± 0.455
2.724GluThr: 2.724 ± 0.544
1.514GluVal: 1.514 ± 0.4
0.757GluTrp: 0.757 ± 0.371
2.27GluTyr: 2.27 ± 0.567
0.0GluXaa: 0.0 ± 0.0
Phe
2.573PheAla: 2.573 ± 0.759
0.303PheCys: 0.303 ± 0.181
2.724PheAsp: 2.724 ± 0.663
1.665PheGlu: 1.665 ± 0.447
1.059PhePhe: 1.059 ± 0.435
1.816PheGly: 1.816 ± 0.613
0.757PheHis: 0.757 ± 0.259
2.119PheIle: 2.119 ± 0.361
2.119PheLys: 2.119 ± 0.386
2.724PheLeu: 2.724 ± 0.402
0.454PheMet: 0.454 ± 0.358
1.514PheAsn: 1.514 ± 0.388
1.968PhePro: 1.968 ± 0.425
1.514PheGln: 1.514 ± 0.455
2.573PheArg: 2.573 ± 0.587
2.573PheSer: 2.573 ± 0.619
2.27PheThr: 2.27 ± 0.583
2.573PheVal: 2.573 ± 0.436
0.151PheTrp: 0.151 ± 0.168
0.908PheTyr: 0.908 ± 0.352
0.0PheXaa: 0.0 ± 0.0
Gly
4.087GlyAla: 4.087 ± 0.729
0.454GlyCys: 0.454 ± 0.192
3.633GlyAsp: 3.633 ± 0.684
2.573GlyGlu: 2.573 ± 0.739
2.119GlyPhe: 2.119 ± 0.529
3.027GlyGly: 3.027 ± 0.746
0.605GlyHis: 0.605 ± 0.309
2.724GlyIle: 2.724 ± 0.941
2.876GlyLys: 2.876 ± 0.832
4.389GlyLeu: 4.389 ± 0.811
1.968GlyMet: 1.968 ± 0.43
1.514GlyAsn: 1.514 ± 0.499
2.27GlyPro: 2.27 ± 0.759
2.724GlyGln: 2.724 ± 0.559
2.422GlyArg: 2.422 ± 0.335
3.178GlySer: 3.178 ± 0.514
4.692GlyThr: 4.692 ± 0.865
3.935GlyVal: 3.935 ± 0.757
0.908GlyTrp: 0.908 ± 0.298
1.362GlyTyr: 1.362 ± 0.512
0.0GlyXaa: 0.0 ± 0.0
His
0.605HisAla: 0.605 ± 0.238
0.303HisCys: 0.303 ± 0.255
1.362HisAsp: 1.362 ± 0.42
1.211HisGlu: 1.211 ± 0.406
1.362HisPhe: 1.362 ± 0.485
0.908HisGly: 0.908 ± 0.318
1.211HisHis: 1.211 ± 0.396
1.665HisIle: 1.665 ± 0.461
1.211HisLys: 1.211 ± 0.468
2.422HisLeu: 2.422 ± 0.526
0.303HisMet: 0.303 ± 0.149
1.514HisAsn: 1.514 ± 0.451
1.362HisPro: 1.362 ± 0.539
0.757HisGln: 0.757 ± 0.369
1.362HisArg: 1.362 ± 0.486
1.514HisSer: 1.514 ± 0.378
1.514HisThr: 1.514 ± 0.413
2.573HisVal: 2.573 ± 0.654
0.454HisTrp: 0.454 ± 0.267
1.059HisTyr: 1.059 ± 0.481
0.0HisXaa: 0.0 ± 0.0
Ile
5.751IleAla: 5.751 ± 0.972
0.908IleCys: 0.908 ± 0.284
5.6IleAsp: 5.6 ± 1.084
3.481IleGlu: 3.481 ± 0.676
1.816IlePhe: 1.816 ± 0.552
3.784IleGly: 3.784 ± 1.168
1.514IleHis: 1.514 ± 0.565
5.146IleIle: 5.146 ± 0.562
3.633IleLys: 3.633 ± 0.847
7.568IleLeu: 7.568 ± 0.794
2.422IleMet: 2.422 ± 0.561
3.481IleAsn: 3.481 ± 0.971
3.935IlePro: 3.935 ± 1.004
2.724IleGln: 2.724 ± 0.522
3.481IleArg: 3.481 ± 0.461
4.995IleSer: 4.995 ± 0.85
4.238IleThr: 4.238 ± 0.717
5.146IleVal: 5.146 ± 0.953
0.757IleTrp: 0.757 ± 0.264
1.968IleTyr: 1.968 ± 0.418
0.0IleXaa: 0.0 ± 0.0
Lys
3.784LysAla: 3.784 ± 0.936
0.0LysCys: 0.0 ± 0.0
3.784LysAsp: 3.784 ± 0.527
2.573LysGlu: 2.573 ± 0.414
1.816LysPhe: 1.816 ± 0.535
2.119LysGly: 2.119 ± 0.649
0.908LysHis: 0.908 ± 0.456
2.573LysIle: 2.573 ± 0.5
3.935LysLys: 3.935 ± 1.02
4.843LysLeu: 4.843 ± 0.795
1.665LysMet: 1.665 ± 0.359
2.573LysAsn: 2.573 ± 0.449
1.665LysPro: 1.665 ± 0.239
3.33LysGln: 3.33 ± 0.582
3.33LysArg: 3.33 ± 0.643
2.876LysSer: 2.876 ± 0.418
2.724LysThr: 2.724 ± 0.644
3.784LysVal: 3.784 ± 0.816
0.605LysTrp: 0.605 ± 0.31
2.876LysTyr: 2.876 ± 1.305
0.0LysXaa: 0.0 ± 0.0
Leu
6.66LeuAla: 6.66 ± 0.545
0.757LeuCys: 0.757 ± 0.305
4.087LeuAsp: 4.087 ± 0.716
6.206LeuGlu: 6.206 ± 0.615
3.027LeuPhe: 3.027 ± 0.817
3.481LeuGly: 3.481 ± 0.566
1.968LeuHis: 1.968 ± 0.357
4.087LeuIle: 4.087 ± 0.578
4.238LeuLys: 4.238 ± 0.6
8.476LeuLeu: 8.476 ± 1.232
3.33LeuMet: 3.33 ± 0.769
4.389LeuAsn: 4.389 ± 0.808
5.146LeuPro: 5.146 ± 0.92
4.692LeuGln: 4.692 ± 0.824
6.357LeuArg: 6.357 ± 0.91
8.022LeuSer: 8.022 ± 0.908
6.811LeuThr: 6.811 ± 0.995
5.146LeuVal: 5.146 ± 0.734
0.757LeuTrp: 0.757 ± 0.385
3.481LeuTyr: 3.481 ± 0.563
0.0LeuXaa: 0.0 ± 0.0
Met
1.514MetAla: 1.514 ± 0.375
0.303MetCys: 0.303 ± 0.154
1.968MetAsp: 1.968 ± 0.4
1.059MetGlu: 1.059 ± 0.283
1.059MetPhe: 1.059 ± 0.441
1.968MetGly: 1.968 ± 0.613
0.605MetHis: 0.605 ± 0.287
2.119MetIle: 2.119 ± 0.411
1.968MetLys: 1.968 ± 0.465
2.422MetLeu: 2.422 ± 0.541
1.059MetMet: 1.059 ± 0.474
1.665MetAsn: 1.665 ± 0.388
0.757MetPro: 0.757 ± 0.345
0.605MetGln: 0.605 ± 0.272
1.816MetArg: 1.816 ± 0.537
2.876MetSer: 2.876 ± 0.594
2.27MetThr: 2.27 ± 0.802
2.119MetVal: 2.119 ± 0.814
0.151MetTrp: 0.151 ± 0.149
0.757MetTyr: 0.757 ± 0.275
0.0MetXaa: 0.0 ± 0.0
Asn
2.27AsnAla: 2.27 ± 0.456
0.454AsnCys: 0.454 ± 0.271
3.481AsnAsp: 3.481 ± 0.743
1.968AsnGlu: 1.968 ± 0.388
2.27AsnPhe: 2.27 ± 0.551
2.422AsnGly: 2.422 ± 1.034
1.059AsnHis: 1.059 ± 0.374
3.935AsnIle: 3.935 ± 0.503
1.816AsnLys: 1.816 ± 0.314
3.784AsnLeu: 3.784 ± 0.846
1.816AsnMet: 1.816 ± 0.309
3.027AsnAsn: 3.027 ± 0.547
1.816AsnPro: 1.816 ± 0.376
2.573AsnGln: 2.573 ± 0.481
2.724AsnArg: 2.724 ± 0.545
3.027AsnSer: 3.027 ± 0.78
2.27AsnThr: 2.27 ± 0.489
3.633AsnVal: 3.633 ± 0.521
0.151AsnTrp: 0.151 ± 0.183
0.908AsnTyr: 0.908 ± 0.358
0.0AsnXaa: 0.0 ± 0.0
Pro
2.119ProAla: 2.119 ± 0.762
0.757ProCys: 0.757 ± 0.346
1.816ProAsp: 1.816 ± 0.386
2.27ProGlu: 2.27 ± 0.573
1.665ProPhe: 1.665 ± 0.348
1.514ProGly: 1.514 ± 0.507
0.908ProHis: 0.908 ± 0.433
2.876ProIle: 2.876 ± 0.574
2.422ProLys: 2.422 ± 0.456
3.027ProLeu: 3.027 ± 0.862
1.514ProMet: 1.514 ± 0.424
2.119ProAsn: 2.119 ± 0.352
2.724ProPro: 2.724 ± 0.814
2.27ProGln: 2.27 ± 0.721
1.816ProArg: 1.816 ± 0.437
3.784ProSer: 3.784 ± 0.774
2.27ProThr: 2.27 ± 0.548
3.633ProVal: 3.633 ± 1.007
0.605ProTrp: 0.605 ± 0.221
2.119ProTyr: 2.119 ± 0.641
0.0ProXaa: 0.0 ± 0.0
Gln
3.33GlnAla: 3.33 ± 0.847
0.303GlnCys: 0.303 ± 0.203
2.422GlnAsp: 2.422 ± 0.637
2.27GlnGlu: 2.27 ± 0.538
0.454GlnPhe: 0.454 ± 0.195
2.876GlnGly: 2.876 ± 0.721
1.665GlnHis: 1.665 ± 0.544
5.297GlnIle: 5.297 ± 0.67
3.178GlnLys: 3.178 ± 0.567
6.811GlnLeu: 6.811 ± 1.356
1.059GlnMet: 1.059 ± 0.408
1.816GlnAsn: 1.816 ± 0.491
1.816GlnPro: 1.816 ± 0.468
2.422GlnGln: 2.422 ± 0.679
2.27GlnArg: 2.27 ± 0.54
1.362GlnSer: 1.362 ± 0.418
1.362GlnThr: 1.362 ± 0.452
2.422GlnVal: 2.422 ± 0.514
0.454GlnTrp: 0.454 ± 0.207
1.816GlnTyr: 1.816 ± 0.618
0.0GlnXaa: 0.0 ± 0.0
Arg
3.935ArgAla: 3.935 ± 0.539
0.908ArgCys: 0.908 ± 0.3
4.692ArgAsp: 4.692 ± 0.941
3.178ArgGlu: 3.178 ± 0.684
2.119ArgPhe: 2.119 ± 0.472
2.724ArgGly: 2.724 ± 0.422
1.514ArgHis: 1.514 ± 0.31
4.692ArgIle: 4.692 ± 0.778
2.724ArgLys: 2.724 ± 0.398
5.751ArgLeu: 5.751 ± 0.72
1.362ArgMet: 1.362 ± 0.272
2.876ArgAsn: 2.876 ± 0.562
1.816ArgPro: 1.816 ± 0.61
1.816ArgGln: 1.816 ± 0.389
5.6ArgArg: 5.6 ± 1.184
4.541ArgSer: 4.541 ± 0.657
3.027ArgThr: 3.027 ± 0.855
4.843ArgVal: 4.843 ± 0.435
0.605ArgTrp: 0.605 ± 0.335
2.573ArgTyr: 2.573 ± 0.652
0.0ArgXaa: 0.0 ± 0.0
Ser
4.843SerAla: 4.843 ± 0.807
0.303SerCys: 0.303 ± 0.193
4.692SerAsp: 4.692 ± 0.361
3.178SerGlu: 3.178 ± 0.629
3.178SerPhe: 3.178 ± 0.669
5.6SerGly: 5.6 ± 1.053
1.059SerHis: 1.059 ± 0.488
5.751SerIle: 5.751 ± 1.052
3.178SerLys: 3.178 ± 0.748
5.751SerLeu: 5.751 ± 0.662
1.816SerMet: 1.816 ± 0.613
4.389SerAsn: 4.389 ± 0.529
2.573SerPro: 2.573 ± 0.561
3.633SerGln: 3.633 ± 0.772
3.784SerArg: 3.784 ± 0.625
6.962SerSer: 6.962 ± 0.709
5.449SerThr: 5.449 ± 1.051
4.843SerVal: 4.843 ± 0.733
0.605SerTrp: 0.605 ± 0.24
3.33SerTyr: 3.33 ± 0.775
0.0SerXaa: 0.0 ± 0.0
Thr
4.087ThrAla: 4.087 ± 1.195
0.454ThrCys: 0.454 ± 0.264
3.935ThrAsp: 3.935 ± 0.753
2.876ThrGlu: 2.876 ± 0.688
2.573ThrPhe: 2.573 ± 0.398
3.027ThrGly: 3.027 ± 0.373
1.816ThrHis: 1.816 ± 0.337
4.692ThrIle: 4.692 ± 1.129
2.724ThrLys: 2.724 ± 0.689
7.416ThrLeu: 7.416 ± 1.255
1.211ThrMet: 1.211 ± 0.368
1.665ThrAsn: 1.665 ± 0.668
3.481ThrPro: 3.481 ± 0.796
2.422ThrGln: 2.422 ± 0.581
4.843ThrArg: 4.843 ± 0.701
4.389ThrSer: 4.389 ± 0.565
6.66ThrThr: 6.66 ± 1.179
5.297ThrVal: 5.297 ± 0.763
0.605ThrTrp: 0.605 ± 0.264
2.573ThrTyr: 2.573 ± 0.497
0.0ThrXaa: 0.0 ± 0.0
Val
4.843ValAla: 4.843 ± 0.864
0.757ValCys: 0.757 ± 0.274
4.541ValAsp: 4.541 ± 0.978
3.633ValGlu: 3.633 ± 0.783
1.362ValPhe: 1.362 ± 0.417
3.935ValGly: 3.935 ± 0.897
2.119ValHis: 2.119 ± 0.531
4.995ValIle: 4.995 ± 1.399
3.784ValLys: 3.784 ± 0.844
6.508ValLeu: 6.508 ± 0.884
2.724ValMet: 2.724 ± 0.56
2.876ValAsn: 2.876 ± 0.447
3.33ValPro: 3.33 ± 0.363
2.724ValGln: 2.724 ± 0.538
3.935ValArg: 3.935 ± 0.627
5.297ValSer: 5.297 ± 0.833
4.541ValThr: 4.541 ± 0.626
4.541ValVal: 4.541 ± 1.001
0.605ValTrp: 0.605 ± 0.343
3.481ValTyr: 3.481 ± 0.586
0.0ValXaa: 0.0 ± 0.0
Trp
0.303TrpAla: 0.303 ± 0.19
0.151TrpCys: 0.151 ± 0.149
0.151TrpAsp: 0.151 ± 0.145
0.454TrpGlu: 0.454 ± 0.244
0.0TrpPhe: 0.0 ± 0.0
0.303TrpGly: 0.303 ± 0.154
0.454TrpHis: 0.454 ± 0.299
1.059TrpIle: 1.059 ± 0.536
0.605TrpLys: 0.605 ± 0.307
0.454TrpLeu: 0.454 ± 0.31
0.454TrpMet: 0.454 ± 0.175
0.908TrpAsn: 0.908 ± 0.274
0.151TrpPro: 0.151 ± 0.137
0.151TrpGln: 0.151 ± 0.168
0.454TrpArg: 0.454 ± 0.198
0.757TrpSer: 0.757 ± 0.533
0.605TrpThr: 0.605 ± 0.333
0.908TrpVal: 0.908 ± 0.343
0.0TrpTrp: 0.0 ± 0.0
1.059TrpTyr: 1.059 ± 0.223
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.665TyrAla: 1.665 ± 0.332
0.151TyrCys: 0.151 ± 0.145
3.33TyrAsp: 3.33 ± 0.581
1.514TyrGlu: 1.514 ± 0.295
0.605TyrPhe: 0.605 ± 0.262
4.087TyrGly: 4.087 ± 0.788
1.362TyrHis: 1.362 ± 0.466
2.573TyrIle: 2.573 ± 0.66
1.211TyrLys: 1.211 ± 0.514
2.724TyrLeu: 2.724 ± 0.438
1.211TyrMet: 1.211 ± 0.463
2.27TyrAsn: 2.27 ± 0.414
1.514TyrPro: 1.514 ± 0.432
2.422TyrGln: 2.422 ± 0.466
2.27TyrArg: 2.27 ± 0.457
2.422TyrSer: 2.422 ± 0.66
2.573TyrThr: 2.573 ± 0.482
4.087TyrVal: 4.087 ± 0.677
0.0TyrTrp: 0.0 ± 0.0
1.968TyrTyr: 1.968 ± 0.67
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 12 proteins (6608 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski