Amino acid dipepetide frequency for Stenotrophomonas chelatiphaga

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	18.596AlaAla: 18.596 ± 0.209	1.165AlaCys: 1.165 ± 0.03	7.493AlaAsp: 7.493 ± 0.085	6.656AlaGlu: 6.656 ± 0.093	3.976AlaPhe: 3.976 ± 0.063	11.535AlaGly: 11.535 ± 0.134	2.514AlaHis: 2.514 ± 0.052	4.994AlaIle: 4.994 ± 0.077	3.078AlaLys: 3.078 ± 0.068	15.888AlaLeu: 15.888 ± 0.164	3.292AlaMet: 3.292 ± 0.064	2.966AlaAsn: 2.966 ± 0.074	6.576AlaPro: 6.576 ± 0.115	5.728AlaGln: 5.728 ± 0.07	9.283AlaArg: 9.283 ± 0.113	7.146AlaSer: 7.146 ± 0.099	6.355AlaThr: 6.355 ± 0.109	9.316AlaVal: 9.316 ± 0.12	2.068AlaTrp: 2.068 ± 0.04	2.465AlaTyr: 2.465 ± 0.045	0.0AlaXaa: 0.0 ± 0.0
Cys	0.947CysAla: 0.947 ± 0.034	0.073CysCys: 0.073 ± 0.008	0.44CysAsp: 0.44 ± 0.028	0.377CysGlu: 0.377 ± 0.028	0.257CysPhe: 0.257 ± 0.014	0.767CysGly: 0.767 ± 0.031	0.201CysHis: 0.201 ± 0.014	0.311CysIle: 0.311 ± 0.016	0.153CysLys: 0.153 ± 0.012	0.8CysLeu: 0.8 ± 0.036	0.14CysMet: 0.14 ± 0.012	0.196CysAsn: 0.196 ± 0.013	0.367CysPro: 0.367 ± 0.021	0.253CysGln: 0.253 ± 0.016	0.526CysArg: 0.526 ± 0.023	0.484CysSer: 0.484 ± 0.021	0.436CysThr: 0.436 ± 0.018	0.63CysVal: 0.63 ± 0.026	0.122CysTrp: 0.122 ± 0.011	0.167CysTyr: 0.167 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	8.593AspAla: 8.593 ± 0.105	0.387AspCys: 0.387 ± 0.021	3.342AspAsp: 3.342 ± 0.067	3.077AspGlu: 3.077 ± 0.063	2.005AspPhe: 2.005 ± 0.042	5.944AspGly: 5.944 ± 0.081	1.218AspHis: 1.218 ± 0.034	2.508AspIle: 2.508 ± 0.051	1.407AspLys: 1.407 ± 0.045	5.507AspLeu: 5.507 ± 0.083	1.089AspMet: 1.089 ± 0.03	1.52AspAsn: 1.52 ± 0.046	3.397AspPro: 3.397 ± 0.056	1.99AspGln: 1.99 ± 0.048	3.812AspArg: 3.812 ± 0.06	2.687AspSer: 2.687 ± 0.053	2.798AspThr: 2.798 ± 0.05	4.352AspVal: 4.352 ± 0.066	1.087AspTrp: 1.087 ± 0.032	1.625AspTyr: 1.625 ± 0.039	0.0AspXaa: 0.0 ± 0.0
Glu	6.512GluAla: 6.512 ± 0.092	0.296GluCys: 0.296 ± 0.018	2.484GluAsp: 2.484 ± 0.059	2.37GluGlu: 2.37 ± 0.054	1.557GluPhe: 1.557 ± 0.046	4.088GluGly: 4.088 ± 0.067	1.25GluHis: 1.25 ± 0.038	2.206GluIle: 2.206 ± 0.046	1.524GluLys: 1.524 ± 0.038	5.851GluLeu: 5.851 ± 0.102	1.086GluMet: 1.086 ± 0.032	1.168GluAsn: 1.168 ± 0.035	2.23GluPro: 2.23 ± 0.052	2.952GluGln: 2.952 ± 0.062	4.659GluArg: 4.659 ± 0.077	2.346GluSer: 2.346 ± 0.048	2.435GluThr: 2.435 ± 0.049	3.696GluVal: 3.696 ± 0.063	0.624GluTrp: 0.624 ± 0.025	0.997GluTyr: 0.997 ± 0.033	0.0GluXaa: 0.0 ± 0.0
Phe	4.087PheAla: 4.087 ± 0.066	0.291PheCys: 0.291 ± 0.017	2.622PheAsp: 2.622 ± 0.056	1.813PheGlu: 1.813 ± 0.041	1.196PhePhe: 1.196 ± 0.045	3.281PheGly: 3.281 ± 0.065	0.751PheHis: 0.751 ± 0.025	1.291PheIle: 1.291 ± 0.034	0.906PheLys: 0.906 ± 0.029	2.935PheLeu: 2.935 ± 0.057	0.658PheMet: 0.658 ± 0.025	1.208PheAsn: 1.208 ± 0.041	1.402PhePro: 1.402 ± 0.037	1.11PheGln: 1.11 ± 0.032	1.908PheArg: 1.908 ± 0.04	2.145PheSer: 2.145 ± 0.064	1.73PheThr: 1.73 ± 0.041	2.433PheVal: 2.433 ± 0.048	0.446PheTrp: 0.446 ± 0.021	0.752PheTyr: 0.752 ± 0.031	0.0PheXaa: 0.0 ± 0.0
Gly	9.385GlyAla: 9.385 ± 0.124	0.775GlyCys: 0.775 ± 0.032	4.623GlyAsp: 4.623 ± 0.061	4.619GlyGlu: 4.619 ± 0.077	3.363GlyPhe: 3.363 ± 0.057	7.358GlyGly: 7.358 ± 0.11	2.007GlyHis: 2.007 ± 0.046	4.036GlyIle: 4.036 ± 0.064	2.912GlyLys: 2.912 ± 0.058	9.071GlyLeu: 9.071 ± 0.102	2.35GlyMet: 2.35 ± 0.05	2.652GlyAsn: 2.652 ± 0.072	3.164GlyPro: 3.164 ± 0.064	3.814GlyGln: 3.814 ± 0.059	6.141GlyArg: 6.141 ± 0.087	5.243GlySer: 5.243 ± 0.092	4.625GlyThr: 4.625 ± 0.099	6.683GlyVal: 6.683 ± 0.081	1.686GlyTrp: 1.686 ± 0.048	2.4GlyTyr: 2.4 ± 0.048	0.0GlyXaa: 0.0 ± 0.0
His	3.177HisAla: 3.177 ± 0.07	0.219HisCys: 0.219 ± 0.016	1.436HisAsp: 1.436 ± 0.039	1.062HisGlu: 1.062 ± 0.032	0.776HisPhe: 0.776 ± 0.031	2.363HisGly: 2.363 ± 0.056	0.579HisHis: 0.579 ± 0.023	0.717HisIle: 0.717 ± 0.026	0.422HisLys: 0.422 ± 0.018	2.126HisLeu: 2.126 ± 0.041	0.424HisMet: 0.424 ± 0.02	0.488HisAsn: 0.488 ± 0.021	1.383HisPro: 1.383 ± 0.035	0.718HisGln: 0.718 ± 0.023	1.559HisArg: 1.559 ± 0.042	0.933HisSer: 0.933 ± 0.033	0.943HisThr: 0.943 ± 0.03	1.637HisVal: 1.637 ± 0.04	0.46HisTrp: 0.46 ± 0.021	0.624HisTyr: 0.624 ± 0.021	0.0HisXaa: 0.0 ± 0.0
Ile	6.092IleAla: 6.092 ± 0.084	0.335IleCys: 0.335 ± 0.019	3.084IleAsp: 3.084 ± 0.057	2.767IleGlu: 2.767 ± 0.055	1.08IlePhe: 1.08 ± 0.035	4.404IleGly: 4.404 ± 0.068	0.804IleHis: 0.804 ± 0.025	1.505IleIle: 1.505 ± 0.037	1.087IleLys: 1.087 ± 0.034	2.898IleLeu: 2.898 ± 0.056	0.54IleMet: 0.54 ± 0.024	1.387IleAsn: 1.387 ± 0.042	1.875IlePro: 1.875 ± 0.044	1.158IleGln: 1.158 ± 0.036	2.462IleArg: 2.462 ± 0.057	2.347IleSer: 2.347 ± 0.046	2.339IleThr: 2.339 ± 0.053	3.034IleVal: 3.034 ± 0.056	0.403IleTrp: 0.403 ± 0.021	0.752IleTyr: 0.752 ± 0.028	0.0IleXaa: 0.0 ± 0.0
Lys	3.234LysAla: 3.234 ± 0.076	0.11LysCys: 0.11 ± 0.01	1.425LysAsp: 1.425 ± 0.038	1.159LysGlu: 1.159 ± 0.038	0.644LysPhe: 0.644 ± 0.023	2.041LysGly: 2.041 ± 0.053	0.554LysHis: 0.554 ± 0.022	1.112LysIle: 1.112 ± 0.037	0.919LysLys: 0.919 ± 0.052	2.827LysLeu: 2.827 ± 0.061	0.57LysMet: 0.57 ± 0.028	0.607LysAsn: 0.607 ± 0.029	1.678LysPro: 1.678 ± 0.044	1.166LysGln: 1.166 ± 0.036	1.992LysArg: 1.992 ± 0.04	1.172LysSer: 1.172 ± 0.037	1.337LysThr: 1.337 ± 0.044	2.259LysVal: 2.259 ± 0.053	0.26LysTrp: 0.26 ± 0.015	0.554LysTyr: 0.554 ± 0.023	0.0LysXaa: 0.0 ± 0.0
Leu	14.92LeuAla: 14.92 ± 0.159	0.93LeuCys: 0.93 ± 0.037	6.911LeuAsp: 6.911 ± 0.092	5.183LeuGlu: 5.183 ± 0.091	3.344LeuPhe: 3.344 ± 0.057	8.955LeuGly: 8.955 ± 0.103	2.613LeuHis: 2.613 ± 0.057	3.722LeuIle: 3.722 ± 0.061	2.958LeuLys: 2.958 ± 0.065	12.769LeuLeu: 12.769 ± 0.188	2.224LeuMet: 2.224 ± 0.052	2.377LeuAsn: 2.377 ± 0.05	6.814LeuPro: 6.814 ± 0.094	5.552LeuGln: 5.552 ± 0.097	8.622LeuArg: 8.622 ± 0.12	6.155LeuSer: 6.155 ± 0.084	4.734LeuThr: 4.734 ± 0.077	8.023LeuVal: 8.023 ± 0.108	1.387LeuTrp: 1.387 ± 0.045	2.199LeuTyr: 2.199 ± 0.048	0.0LeuXaa: 0.0 ± 0.0
Met	2.82MetAla: 2.82 ± 0.05	0.132MetCys: 0.132 ± 0.01	1.171MetAsp: 1.171 ± 0.031	0.904MetGlu: 0.904 ± 0.027	0.615MetPhe: 0.615 ± 0.024	1.638MetGly: 1.638 ± 0.044	0.443MetHis: 0.443 ± 0.019	0.914MetIle: 0.914 ± 0.028	0.74MetLys: 0.74 ± 0.025	2.442MetLeu: 2.442 ± 0.054	0.461MetMet: 0.461 ± 0.019	0.695MetAsn: 0.695 ± 0.022	1.315MetPro: 1.315 ± 0.032	1.051MetGln: 1.051 ± 0.033	1.623MetArg: 1.623 ± 0.04	1.535MetSer: 1.535 ± 0.035	1.34MetThr: 1.34 ± 0.036	1.445MetVal: 1.445 ± 0.038	0.232MetTrp: 0.232 ± 0.015	0.336MetTyr: 0.336 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	3.355AsnAla: 3.355 ± 0.078	0.199AsnCys: 0.199 ± 0.024	1.485AsnAsp: 1.485 ± 0.056	1.264AsnGlu: 1.264 ± 0.036	0.863AsnPhe: 0.863 ± 0.03	2.507AsnGly: 2.507 ± 0.072	0.52AsnHis: 0.52 ± 0.024	1.102AsnIle: 1.102 ± 0.035	0.62AsnLys: 0.62 ± 0.026	2.517AsnLeu: 2.517 ± 0.051	0.427AsnMet: 0.427 ± 0.019	0.774AsnAsn: 0.774 ± 0.035	1.714AsnPro: 1.714 ± 0.046	0.89AsnGln: 0.89 ± 0.028	1.786AsnArg: 1.786 ± 0.043	1.216AsnSer: 1.216 ± 0.042	1.383AsnThr: 1.383 ± 0.04	2.077AsnVal: 2.077 ± 0.059	0.393AsnTrp: 0.393 ± 0.021	0.666AsnTyr: 0.666 ± 0.029	0.0AsnXaa: 0.0 ± 0.0
Pro	7.764ProAla: 7.764 ± 0.123	0.297ProCys: 0.297 ± 0.017	3.345ProAsp: 3.345 ± 0.063	2.805ProGlu: 2.805 ± 0.054	1.622ProPhe: 1.622 ± 0.038	4.808ProGly: 4.808 ± 0.076	1.083ProHis: 1.083 ± 0.033	1.799ProIle: 1.799 ± 0.041	1.226ProLys: 1.226 ± 0.039	5.806ProLeu: 5.806 ± 0.081	1.257ProMet: 1.257 ± 0.03	1.094ProAsn: 1.094 ± 0.035	2.776ProPro: 2.776 ± 0.07	2.203ProGln: 2.203 ± 0.053	3.425ProArg: 3.425 ± 0.053	2.858ProSer: 2.858 ± 0.066	2.403ProThr: 2.403 ± 0.048	4.329ProVal: 4.329 ± 0.077	0.853ProTrp: 0.853 ± 0.03	1.11ProTyr: 1.11 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	6.353GlnAla: 6.353 ± 0.1	0.26GlnCys: 0.26 ± 0.016	1.927GlnAsp: 1.927 ± 0.045	1.578GlnGlu: 1.578 ± 0.043	1.227GlnPhe: 1.227 ± 0.033	3.283GlnGly: 3.283 ± 0.052	1.055GlnHis: 1.055 ± 0.034	1.626GlnIle: 1.626 ± 0.037	0.961GlnLys: 0.961 ± 0.034	5.005GlnLeu: 5.005 ± 0.074	0.889GlnMet: 0.889 ± 0.029	0.746GlnAsn: 0.746 ± 0.031	2.588GlnPro: 2.588 ± 0.054	2.682GlnGln: 2.682 ± 0.062	4.124GlnArg: 4.124 ± 0.078	1.888GlnSer: 1.888 ± 0.042	1.711GlnThr: 1.711 ± 0.041	3.739GlnVal: 3.739 ± 0.062	0.765GlnTrp: 0.765 ± 0.028	0.847GlnTyr: 0.847 ± 0.028	0.0GlnXaa: 0.0 ± 0.0
Arg	8.233ArgAla: 8.233 ± 0.107	0.535ArgCys: 0.535 ± 0.022	4.37ArgAsp: 4.37 ± 0.069	4.224ArgGlu: 4.224 ± 0.077	2.871ArgPhe: 2.871 ± 0.051	5.296ArgGly: 5.296 ± 0.078	1.857ArgHis: 1.857 ± 0.041	3.646ArgIle: 3.646 ± 0.06	1.705ArgLys: 1.705 ± 0.042	8.2ArgLeu: 8.2 ± 0.118	1.903ArgMet: 1.903 ± 0.039	1.993ArgAsn: 1.993 ± 0.041	3.342ArgPro: 3.342 ± 0.057	3.326ArgGln: 3.326 ± 0.066	5.717ArgArg: 5.717 ± 0.093	4.033ArgSer: 4.033 ± 0.06	3.401ArgThr: 3.401 ± 0.053	5.183ArgVal: 5.183 ± 0.07	1.445ArgTrp: 1.445 ± 0.045	2.013ArgTyr: 2.013 ± 0.043	0.0ArgXaa: 0.0 ± 0.0
Ser	6.829SerAla: 6.829 ± 0.083	0.355SerCys: 0.355 ± 0.018	2.755SerAsp: 2.755 ± 0.056	2.563SerGlu: 2.563 ± 0.049	1.902SerPhe: 1.902 ± 0.049	5.292SerGly: 5.292 ± 0.087	1.106SerHis: 1.106 ± 0.031	2.326SerIle: 2.326 ± 0.05	1.267SerLys: 1.267 ± 0.035	5.906SerLeu: 5.906 ± 0.082	1.146SerMet: 1.146 ± 0.031	1.569SerAsn: 1.569 ± 0.046	2.915SerPro: 2.915 ± 0.053	1.985SerGln: 1.985 ± 0.044	3.772SerArg: 3.772 ± 0.064	3.189SerSer: 3.189 ± 0.058	2.971SerThr: 2.971 ± 0.072	4.114SerVal: 4.114 ± 0.092	0.898SerTrp: 0.898 ± 0.029	1.307SerTyr: 1.307 ± 0.04	0.0SerXaa: 0.0 ± 0.0
Thr	6.409ThrAla: 6.409 ± 0.121	0.339ThrCys: 0.339 ± 0.019	2.639ThrAsp: 2.639 ± 0.051	2.129ThrGlu: 2.129 ± 0.043	1.661ThrPhe: 1.661 ± 0.047	4.672ThrGly: 4.672 ± 0.076	1.049ThrHis: 1.049 ± 0.031	1.857ThrIle: 1.857 ± 0.05	0.876ThrLys: 0.876 ± 0.034	6.434ThrLeu: 6.434 ± 0.082	0.879ThrMet: 0.879 ± 0.03	1.109ThrAsn: 1.109 ± 0.042	3.421ThrPro: 3.421 ± 0.089	1.679ThrGln: 1.679 ± 0.037	3.45ThrArg: 3.45 ± 0.065	2.444ThrSer: 2.444 ± 0.058	2.595ThrThr: 2.595 ± 0.063	4.016ThrVal: 4.016 ± 0.077	0.68ThrTrp: 0.68 ± 0.026	1.09ThrTyr: 1.09 ± 0.044	0.0ThrXaa: 0.0 ± 0.0
Val	9.742ValAla: 9.742 ± 0.135	0.617ValCys: 0.617 ± 0.044	4.737ValAsp: 4.737 ± 0.073	4.183ValGlu: 4.183 ± 0.069	2.576ValPhe: 2.576 ± 0.055	5.779ValGly: 5.779 ± 0.107	1.642ValHis: 1.642 ± 0.034	3.264ValIle: 3.264 ± 0.059	1.857ValLys: 1.857 ± 0.053	8.712ValLeu: 8.712 ± 0.097	1.68ValMet: 1.68 ± 0.043	2.036ValAsn: 2.036 ± 0.053	4.021ValPro: 4.021 ± 0.071	3.086ValGln: 3.086 ± 0.053	5.261ValArg: 5.261 ± 0.078	4.211ValSer: 4.211 ± 0.077	3.865ValThr: 3.865 ± 0.077	6.373ValVal: 6.373 ± 0.082	0.867ValTrp: 0.867 ± 0.034	1.455ValTyr: 1.455 ± 0.037	0.0ValXaa: 0.0 ± 0.0
Trp	1.329TrpAla: 1.329 ± 0.037	0.142TrpCys: 0.142 ± 0.011	0.73TrpAsp: 0.73 ± 0.026	0.569TrpGlu: 0.569 ± 0.024	0.562TrpPhe: 0.562 ± 0.026	0.984TrpGly: 0.984 ± 0.038	0.357TrpHis: 0.357 ± 0.018	0.69TrpIle: 0.69 ± 0.026	0.48TrpLys: 0.48 ± 0.019	2.207TrpLeu: 2.207 ± 0.06	0.485TrpMet: 0.485 ± 0.02	0.521TrpAsn: 0.521 ± 0.023	0.781TrpPro: 0.781 ± 0.03	0.928TrpGln: 0.928 ± 0.031	1.275TrpArg: 1.275 ± 0.035	0.893TrpSer: 0.893 ± 0.029	0.795TrpThr: 0.795 ± 0.024	0.994TrpVal: 0.994 ± 0.029	0.34TrpTrp: 0.34 ± 0.018	0.331TrpTyr: 0.331 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.712TyrAla: 2.712 ± 0.056	0.189TyrCys: 0.189 ± 0.013	1.326TyrAsp: 1.326 ± 0.04	1.027TyrGlu: 1.027 ± 0.032	0.869TyrPhe: 0.869 ± 0.029	1.911TyrGly: 1.911 ± 0.044	0.445TyrHis: 0.445 ± 0.019	0.726TyrIle: 0.726 ± 0.025	0.523TyrLys: 0.523 ± 0.026	2.491TyrLeu: 2.491 ± 0.049	0.35TyrMet: 0.35 ± 0.018	0.651TyrAsn: 0.651 ± 0.027	1.105TyrPro: 1.105 ± 0.032	0.981TyrGln: 0.981 ± 0.048	1.899TyrArg: 1.899 ± 0.044	1.243TyrSer: 1.243 ± 0.037	1.233TyrThr: 1.233 ± 0.041	1.633TyrVal: 1.633 ± 0.04	0.375TyrTrp: 0.375 ± 0.017	0.643TyrTyr: 0.643 ± 0.029	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3376 proteins (1140280 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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