Amino acid dipepetide frequency for Grass carp reovirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.274AlaAla: 7.274 ± 1.154
1.149AlaCys: 1.149 ± 0.476
4.722AlaAsp: 4.722 ± 0.904
2.552AlaGlu: 2.552 ± 0.726
3.446AlaPhe: 3.446 ± 0.698
6.381AlaGly: 6.381 ± 1.069
1.404AlaHis: 1.404 ± 0.515
5.487AlaIle: 5.487 ± 0.524
2.808AlaLys: 2.808 ± 0.939
8.678AlaLeu: 8.678 ± 1.018
2.935AlaMet: 2.935 ± 0.595
3.063AlaAsn: 3.063 ± 0.402
3.956AlaPro: 3.956 ± 0.539
2.808AlaGln: 2.808 ± 0.586
4.084AlaArg: 4.084 ± 0.671
6.636AlaSer: 6.636 ± 1.144
6.381AlaThr: 6.381 ± 0.383
4.722AlaVal: 4.722 ± 0.894
0.893AlaTrp: 0.893 ± 0.298
3.956AlaTyr: 3.956 ± 0.819
0.0AlaXaa: 0.0 ± 0.0
Cys
1.021CysAla: 1.021 ± 0.435
0.383CysCys: 0.383 ± 0.2
1.531CysAsp: 1.531 ± 0.443
0.638CysGlu: 0.638 ± 0.183
0.383CysPhe: 0.383 ± 0.187
1.021CysGly: 1.021 ± 0.294
0.255CysHis: 0.255 ± 0.17
1.021CysIle: 1.021 ± 0.491
1.149CysLys: 1.149 ± 0.286
1.914CysLeu: 1.914 ± 0.411
0.0CysMet: 0.0 ± 0.0
0.383CysAsn: 0.383 ± 0.259
0.766CysPro: 0.766 ± 0.2
0.51CysGln: 0.51 ± 0.221
0.766CysArg: 0.766 ± 0.291
0.893CysSer: 0.893 ± 0.362
1.021CysThr: 1.021 ± 0.405
0.51CysVal: 0.51 ± 0.167
0.383CysTrp: 0.383 ± 0.177
0.893CysTyr: 0.893 ± 0.449
0.0CysXaa: 0.0 ± 0.0
Asp
5.36AspAla: 5.36 ± 0.899
0.383AspCys: 0.383 ± 0.217
4.211AspAsp: 4.211 ± 0.756
3.956AspGlu: 3.956 ± 0.585
1.787AspPhe: 1.787 ± 0.232
3.956AspGly: 3.956 ± 0.705
1.021AspHis: 1.021 ± 0.399
5.232AspIle: 5.232 ± 0.948
2.297AspLys: 2.297 ± 0.386
5.87AspLeu: 5.87 ± 0.677
1.914AspMet: 1.914 ± 0.573
1.276AspAsn: 1.276 ± 0.404
3.063AspPro: 3.063 ± 1.099
1.021AspGln: 1.021 ± 0.353
3.701AspArg: 3.701 ± 0.77
3.318AspSer: 3.318 ± 0.7
4.339AspThr: 4.339 ± 0.805
6.253AspVal: 6.253 ± 0.932
1.659AspTrp: 1.659 ± 0.486
2.169AspTyr: 2.169 ± 0.633
0.0AspXaa: 0.0 ± 0.0
Glu
3.19GluAla: 3.19 ± 0.543
0.766GluCys: 0.766 ± 0.303
2.042GluAsp: 2.042 ± 0.437
1.149GluGlu: 1.149 ± 0.441
1.531GluPhe: 1.531 ± 0.355
1.404GluGly: 1.404 ± 0.26
2.042GluHis: 2.042 ± 0.817
2.042GluIle: 2.042 ± 0.457
2.042GluLys: 2.042 ± 0.401
3.828GluLeu: 3.828 ± 0.563
1.659GluMet: 1.659 ± 0.352
1.021GluAsn: 1.021 ± 0.34
2.808GluPro: 2.808 ± 0.709
1.021GluGln: 1.021 ± 0.319
1.914GluArg: 1.914 ± 0.575
3.19GluSer: 3.19 ± 0.416
2.297GluThr: 2.297 ± 0.668
2.425GluVal: 2.425 ± 0.371
1.149GluTrp: 1.149 ± 0.365
1.276GluTyr: 1.276 ± 0.407
0.0GluXaa: 0.0 ± 0.0
Phe
1.531PheAla: 1.531 ± 0.359
0.638PheCys: 0.638 ± 0.342
2.935PheAsp: 2.935 ± 0.576
1.276PheGlu: 1.276 ± 0.208
1.021PhePhe: 1.021 ± 0.227
2.68PheGly: 2.68 ± 0.604
0.383PheHis: 0.383 ± 0.171
2.042PheIle: 2.042 ± 0.549
1.404PheLys: 1.404 ± 0.365
3.063PheLeu: 3.063 ± 0.531
1.149PheMet: 1.149 ± 0.434
1.531PheAsn: 1.531 ± 0.504
2.552PhePro: 2.552 ± 0.742
1.531PheGln: 1.531 ± 0.327
1.914PheArg: 1.914 ± 0.528
3.701PheSer: 3.701 ± 0.692
2.042PheThr: 2.042 ± 0.442
2.68PheVal: 2.68 ± 0.537
0.383PheTrp: 0.383 ± 0.239
0.893PheTyr: 0.893 ± 0.392
0.0PheXaa: 0.0 ± 0.0
Gly
4.594GlyAla: 4.594 ± 0.55
0.766GlyCys: 0.766 ± 0.248
4.594GlyAsp: 4.594 ± 0.597
1.659GlyGlu: 1.659 ± 0.518
2.935GlyPhe: 2.935 ± 0.512
3.828GlyGly: 3.828 ± 1.014
1.021GlyHis: 1.021 ± 0.231
2.935GlyIle: 2.935 ± 0.554
2.552GlyLys: 2.552 ± 0.75
3.828GlyLeu: 3.828 ± 0.781
2.042GlyMet: 2.042 ± 0.379
3.19GlyAsn: 3.19 ± 0.845
2.935GlyPro: 2.935 ± 0.433
1.531GlyGln: 1.531 ± 0.379
4.467GlyArg: 4.467 ± 0.446
3.446GlySer: 3.446 ± 0.671
4.339GlyThr: 4.339 ± 1.395
6.636GlyVal: 6.636 ± 1.074
1.276GlyTrp: 1.276 ± 0.414
2.297GlyTyr: 2.297 ± 0.447
0.0GlyXaa: 0.0 ± 0.0
His
2.808HisAla: 2.808 ± 0.801
0.128HisCys: 0.128 ± 0.124
1.021HisAsp: 1.021 ± 0.27
1.276HisGlu: 1.276 ± 0.362
0.255HisPhe: 0.255 ± 0.178
2.042HisGly: 2.042 ± 0.315
0.383HisHis: 0.383 ± 0.213
1.404HisIle: 1.404 ± 0.271
0.51HisLys: 0.51 ± 0.345
1.659HisLeu: 1.659 ± 0.561
0.51HisMet: 0.51 ± 0.279
0.51HisAsn: 0.51 ± 0.221
1.021HisPro: 1.021 ± 0.344
0.638HisGln: 0.638 ± 0.282
1.276HisArg: 1.276 ± 0.401
1.787HisSer: 1.787 ± 0.491
1.914HisThr: 1.914 ± 0.468
1.021HisVal: 1.021 ± 0.426
0.51HisTrp: 0.51 ± 0.275
0.638HisTyr: 0.638 ± 0.256
0.0HisXaa: 0.0 ± 0.0
Ile
4.977IleAla: 4.977 ± 0.709
1.787IleCys: 1.787 ± 0.435
5.232IleAsp: 5.232 ± 0.87
1.531IleGlu: 1.531 ± 0.436
1.659IlePhe: 1.659 ± 0.379
3.446IleGly: 3.446 ± 0.55
1.149IleHis: 1.149 ± 0.279
2.169IleIle: 2.169 ± 0.435
1.404IleLys: 1.404 ± 0.349
4.084IleLeu: 4.084 ± 0.666
1.276IleMet: 1.276 ± 0.408
2.68IleAsn: 2.68 ± 0.405
3.446IlePro: 3.446 ± 0.416
1.787IleGln: 1.787 ± 0.4
3.573IleArg: 3.573 ± 0.664
4.722IleSer: 4.722 ± 0.649
3.828IleThr: 3.828 ± 0.648
4.594IleVal: 4.594 ± 0.577
0.893IleTrp: 0.893 ± 0.336
2.042IleTyr: 2.042 ± 0.463
0.0IleXaa: 0.0 ± 0.0
Lys
2.425LysAla: 2.425 ± 0.336
0.255LysCys: 0.255 ± 0.17
1.149LysAsp: 1.149 ± 0.282
2.169LysGlu: 2.169 ± 0.688
1.276LysPhe: 1.276 ± 0.39
1.531LysGly: 1.531 ± 0.432
0.638LysHis: 0.638 ± 0.234
2.042LysIle: 2.042 ± 0.414
1.276LysLys: 1.276 ± 0.286
4.084LysLeu: 4.084 ± 0.877
1.021LysMet: 1.021 ± 0.385
0.638LysAsn: 0.638 ± 0.355
1.787LysPro: 1.787 ± 0.518
1.276LysGln: 1.276 ± 0.409
1.531LysArg: 1.531 ± 0.605
1.787LysSer: 1.787 ± 0.385
2.169LysThr: 2.169 ± 0.415
2.808LysVal: 2.808 ± 0.473
1.149LysTrp: 1.149 ± 0.499
1.404LysTyr: 1.404 ± 0.307
0.0LysXaa: 0.0 ± 0.0
Leu
7.657LeuAla: 7.657 ± 1.107
1.404LeuCys: 1.404 ± 0.29
5.36LeuAsp: 5.36 ± 0.966
3.701LeuGlu: 3.701 ± 0.585
4.467LeuPhe: 4.467 ± 0.713
5.615LeuGly: 5.615 ± 0.894
2.297LeuHis: 2.297 ± 0.433
4.594LeuIle: 4.594 ± 0.667
3.446LeuLys: 3.446 ± 0.592
11.996LeuLeu: 11.996 ± 1.179
3.063LeuMet: 3.063 ± 0.885
3.828LeuAsn: 3.828 ± 0.648
5.487LeuPro: 5.487 ± 0.869
3.446LeuGln: 3.446 ± 0.828
8.04LeuArg: 8.04 ± 0.52
9.826LeuSer: 9.826 ± 1.093
8.678LeuThr: 8.678 ± 1.718
3.573LeuVal: 3.573 ± 0.524
1.659LeuTrp: 1.659 ± 0.568
2.68LeuTyr: 2.68 ± 0.561
0.0LeuXaa: 0.0 ± 0.0
Met
2.552MetAla: 2.552 ± 0.451
0.128MetCys: 0.128 ± 0.136
2.169MetAsp: 2.169 ± 0.538
0.893MetGlu: 0.893 ± 0.369
1.021MetPhe: 1.021 ± 0.274
2.042MetGly: 2.042 ± 0.523
0.51MetHis: 0.51 ± 0.166
1.659MetIle: 1.659 ± 0.402
0.766MetLys: 0.766 ± 0.255
3.701MetLeu: 3.701 ± 0.669
0.638MetMet: 0.638 ± 0.218
0.766MetAsn: 0.766 ± 0.234
1.404MetPro: 1.404 ± 0.41
1.276MetGln: 1.276 ± 0.342
1.659MetArg: 1.659 ± 0.589
2.425MetSer: 2.425 ± 0.625
1.787MetThr: 1.787 ± 0.38
2.042MetVal: 2.042 ± 0.38
0.51MetTrp: 0.51 ± 0.184
0.766MetTyr: 0.766 ± 0.372
0.0MetXaa: 0.0 ± 0.0
Asn
4.339AsnAla: 4.339 ± 0.699
0.51AsnCys: 0.51 ± 0.205
2.552AsnAsp: 2.552 ± 0.724
2.042AsnGlu: 2.042 ± 0.406
0.893AsnPhe: 0.893 ± 0.287
2.68AsnGly: 2.68 ± 0.528
0.51AsnHis: 0.51 ± 0.249
2.552AsnIle: 2.552 ± 0.637
0.893AsnLys: 0.893 ± 0.325
3.318AsnLeu: 3.318 ± 0.559
1.276AsnMet: 1.276 ± 0.478
1.021AsnAsn: 1.021 ± 0.247
1.787AsnPro: 1.787 ± 0.529
0.638AsnGln: 0.638 ± 0.228
2.042AsnArg: 2.042 ± 0.4
3.19AsnSer: 3.19 ± 0.694
2.425AsnThr: 2.425 ± 0.721
3.828AsnVal: 3.828 ± 0.496
0.383AsnTrp: 0.383 ± 0.286
1.404AsnTyr: 1.404 ± 0.313
0.0AsnXaa: 0.0 ± 0.0
Pro
4.339ProAla: 4.339 ± 0.845
0.0ProCys: 0.0 ± 0.0
3.19ProAsp: 3.19 ± 0.585
2.425ProGlu: 2.425 ± 0.545
2.297ProPhe: 2.297 ± 0.581
3.446ProGly: 3.446 ± 0.465
0.893ProHis: 0.893 ± 0.285
2.552ProIle: 2.552 ± 0.644
1.531ProLys: 1.531 ± 0.537
7.785ProLeu: 7.785 ± 0.896
1.659ProMet: 1.659 ± 0.398
2.808ProAsn: 2.808 ± 0.325
5.232ProPro: 5.232 ± 0.852
1.531ProGln: 1.531 ± 0.51
2.297ProArg: 2.297 ± 0.474
4.084ProSer: 4.084 ± 0.763
4.339ProThr: 4.339 ± 0.911
4.084ProVal: 4.084 ± 0.837
1.021ProTrp: 1.021 ± 0.269
1.276ProTyr: 1.276 ± 0.342
0.0ProXaa: 0.0 ± 0.0
Gln
2.808GlnAla: 2.808 ± 0.459
0.255GlnCys: 0.255 ± 0.167
1.659GlnAsp: 1.659 ± 0.478
1.021GlnGlu: 1.021 ± 0.335
1.531GlnPhe: 1.531 ± 0.414
1.276GlnGly: 1.276 ± 0.464
1.531GlnHis: 1.531 ± 0.457
1.404GlnIle: 1.404 ± 0.32
0.51GlnLys: 0.51 ± 0.21
4.084GlnLeu: 4.084 ± 0.949
0.893GlnMet: 0.893 ± 0.233
1.404GlnAsn: 1.404 ± 0.322
1.404GlnPro: 1.404 ± 0.291
1.787GlnGln: 1.787 ± 0.707
2.042GlnArg: 2.042 ± 0.538
3.063GlnSer: 3.063 ± 0.315
2.042GlnThr: 2.042 ± 0.383
2.169GlnVal: 2.169 ± 0.578
1.021GlnTrp: 1.021 ± 0.395
1.404GlnTyr: 1.404 ± 0.325
0.0GlnXaa: 0.0 ± 0.0
Arg
4.722ArgAla: 4.722 ± 0.696
1.404ArgCys: 1.404 ± 0.491
4.722ArgAsp: 4.722 ± 0.95
1.914ArgGlu: 1.914 ± 0.383
1.531ArgPhe: 1.531 ± 0.338
2.808ArgGly: 2.808 ± 0.572
1.021ArgHis: 1.021 ± 0.409
3.19ArgIle: 3.19 ± 0.4
2.297ArgLys: 2.297 ± 0.545
7.019ArgLeu: 7.019 ± 0.876
1.531ArgMet: 1.531 ± 0.26
2.552ArgAsn: 2.552 ± 0.596
2.297ArgPro: 2.297 ± 0.596
2.552ArgGln: 2.552 ± 0.543
5.743ArgArg: 5.743 ± 0.911
4.339ArgSer: 4.339 ± 0.724
3.573ArgThr: 3.573 ± 0.654
5.615ArgVal: 5.615 ± 0.936
1.276ArgTrp: 1.276 ± 0.337
2.297ArgTyr: 2.297 ± 0.453
0.0ArgXaa: 0.0 ± 0.0
Ser
7.274SerAla: 7.274 ± 1.371
1.276SerCys: 1.276 ± 0.616
5.487SerAsp: 5.487 ± 0.892
2.808SerGlu: 2.808 ± 0.497
2.935SerPhe: 2.935 ± 0.773
5.487SerGly: 5.487 ± 1.03
1.659SerHis: 1.659 ± 0.567
3.318SerIle: 3.318 ± 0.51
2.935SerLys: 2.935 ± 0.314
7.402SerLeu: 7.402 ± 0.951
2.425SerMet: 2.425 ± 0.725
2.552SerAsn: 2.552 ± 0.537
4.084SerPro: 4.084 ± 0.643
2.425SerGln: 2.425 ± 0.527
5.998SerArg: 5.998 ± 1.076
5.998SerSer: 5.998 ± 1.31
8.295SerThr: 8.295 ± 0.623
3.828SerVal: 3.828 ± 0.413
1.149SerTrp: 1.149 ± 0.435
2.169SerTyr: 2.169 ± 0.462
0.0SerXaa: 0.0 ± 0.0
Thr
7.912ThrAla: 7.912 ± 0.923
1.531ThrCys: 1.531 ± 0.325
3.446ThrAsp: 3.446 ± 0.449
2.935ThrGlu: 2.935 ± 0.699
2.808ThrPhe: 2.808 ± 0.46
4.467ThrGly: 4.467 ± 0.966
1.659ThrHis: 1.659 ± 0.262
4.339ThrIle: 4.339 ± 0.937
1.021ThrLys: 1.021 ± 0.381
7.147ThrLeu: 7.147 ± 1.006
1.149ThrMet: 1.149 ± 0.283
2.68ThrAsn: 2.68 ± 0.674
4.211ThrPro: 4.211 ± 0.777
2.935ThrGln: 2.935 ± 0.558
3.318ThrArg: 3.318 ± 0.477
6.508ThrSer: 6.508 ± 1.051
6.508ThrThr: 6.508 ± 1.243
5.232ThrVal: 5.232 ± 1.246
0.893ThrTrp: 0.893 ± 0.363
2.552ThrTyr: 2.552 ± 0.696
0.0ThrXaa: 0.0 ± 0.0
Val
4.467ValAla: 4.467 ± 0.71
1.787ValCys: 1.787 ± 0.519
3.701ValAsp: 3.701 ± 0.911
3.063ValGlu: 3.063 ± 0.482
1.659ValPhe: 1.659 ± 0.341
4.084ValGly: 4.084 ± 0.725
1.914ValHis: 1.914 ± 0.602
4.339ValIle: 4.339 ± 0.786
2.169ValLys: 2.169 ± 0.585
6.508ValLeu: 6.508 ± 1.2
1.914ValMet: 1.914 ± 0.57
3.701ValAsn: 3.701 ± 0.627
5.487ValPro: 5.487 ± 1.414
2.935ValGln: 2.935 ± 0.483
4.339ValArg: 4.339 ± 1.119
6.636ValSer: 6.636 ± 0.655
4.084ValThr: 4.084 ± 1.283
4.211ValVal: 4.211 ± 0.918
0.893ValTrp: 0.893 ± 0.227
1.404ValTyr: 1.404 ± 0.337
0.0ValXaa: 0.0 ± 0.0
Trp
1.021TrpAla: 1.021 ± 0.4
0.255TrpCys: 0.255 ± 0.146
0.638TrpAsp: 0.638 ± 0.197
0.51TrpGlu: 0.51 ± 0.295
0.893TrpPhe: 0.893 ± 0.345
0.638TrpGly: 0.638 ± 0.214
0.383TrpHis: 0.383 ± 0.273
1.531TrpIle: 1.531 ± 0.3
0.51TrpLys: 0.51 ± 0.302
1.787TrpLeu: 1.787 ± 0.577
0.893TrpMet: 0.893 ± 0.38
0.638TrpAsn: 0.638 ± 0.231
1.531TrpPro: 1.531 ± 0.435
0.255TrpGln: 0.255 ± 0.164
1.787TrpArg: 1.787 ± 0.501
1.787TrpSer: 1.787 ± 0.456
1.787TrpThr: 1.787 ± 0.937
0.638TrpVal: 0.638 ± 0.177
0.383TrpTrp: 0.383 ± 0.242
0.128TrpTyr: 0.128 ± 0.137
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.063TyrAla: 3.063 ± 0.684
0.638TyrCys: 0.638 ± 0.322
2.425TyrAsp: 2.425 ± 0.336
1.276TyrGlu: 1.276 ± 0.382
1.021TyrPhe: 1.021 ± 0.427
2.042TyrGly: 2.042 ± 0.468
0.638TyrHis: 0.638 ± 0.259
2.425TyrIle: 2.425 ± 0.413
0.893TyrLys: 0.893 ± 0.313
3.063TyrLeu: 3.063 ± 0.518
0.638TyrMet: 0.638 ± 0.377
2.042TyrAsn: 2.042 ± 0.595
1.531TyrPro: 1.531 ± 0.442
1.404TyrGln: 1.404 ± 0.267
1.914TyrArg: 1.914 ± 0.396
2.297TyrSer: 2.297 ± 0.394
1.404TyrThr: 1.404 ± 0.383
2.425TyrVal: 2.425 ± 0.616
0.51TyrTrp: 0.51 ± 0.223
1.404TyrTyr: 1.404 ± 0.489
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 11 proteins (7837 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski