Amino acid dipepetide frequency for Clerodendrum golden mosaic China virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.001AlaAla: 3.001 ± 1.313
0.6AlaCys: 0.6 ± 0.634
1.2AlaAsp: 1.2 ± 0.791
2.401AlaGlu: 2.401 ± 0.702
0.6AlaPhe: 0.6 ± 0.56
1.2AlaGly: 1.2 ± 0.711
2.401AlaHis: 2.401 ± 0.727
0.6AlaIle: 0.6 ± 0.613
5.402AlaLys: 5.402 ± 0.976
6.603AlaLeu: 6.603 ± 1.524
0.6AlaMet: 0.6 ± 0.56
2.401AlaAsn: 2.401 ± 1.13
2.401AlaPro: 2.401 ± 1.663
3.001AlaGln: 3.001 ± 1.254
4.202AlaArg: 4.202 ± 1.441
6.603AlaSer: 6.603 ± 2.358
4.202AlaThr: 4.202 ± 1.305
1.2AlaVal: 1.2 ± 0.952
0.6AlaTrp: 0.6 ± 0.493
1.801AlaTyr: 1.801 ± 1.016
0.0AlaXaa: 0.0 ± 0.0
Cys
0.6CysAla: 0.6 ± 0.634
0.6CysCys: 0.6 ± 0.655
1.2CysAsp: 1.2 ± 1.12
0.6CysGlu: 0.6 ± 0.554
0.6CysPhe: 0.6 ± 0.655
1.2CysGly: 1.2 ± 0.671
0.6CysHis: 0.6 ± 0.613
1.801CysIle: 1.801 ± 1.148
1.2CysLys: 1.2 ± 0.782
1.2CysLeu: 1.2 ± 0.835
1.801CysMet: 1.801 ± 1.324
2.401CysAsn: 2.401 ± 1.091
1.2CysPro: 1.2 ± 1.269
0.0CysGln: 0.0 ± 0.0
1.2CysArg: 1.2 ± 0.604
2.401CysSer: 2.401 ± 1.007
0.6CysThr: 0.6 ± 0.493
0.6CysVal: 0.6 ± 0.554
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.801AspAla: 1.801 ± 1.48
1.2AspCys: 1.2 ± 0.915
1.801AspAsp: 1.801 ± 0.89
1.2AspGlu: 1.2 ± 0.611
2.401AspPhe: 2.401 ± 0.906
3.601AspGly: 3.601 ± 1.383
0.6AspHis: 0.6 ± 0.523
3.001AspIle: 3.001 ± 1.445
1.2AspLys: 1.2 ± 0.642
4.802AspLeu: 4.802 ± 1.367
0.6AspMet: 0.6 ± 0.634
1.801AspAsn: 1.801 ± 0.727
3.601AspPro: 3.601 ± 1.375
0.6AspGln: 0.6 ± 0.523
3.601AspArg: 3.601 ± 1.109
4.802AspSer: 4.802 ± 1.232
3.601AspThr: 3.601 ± 1.141
4.802AspVal: 4.802 ± 1.434
1.2AspTrp: 1.2 ± 0.671
1.801AspTyr: 1.801 ± 1.09
0.0AspXaa: 0.0 ± 0.0
Glu
3.601GluAla: 3.601 ± 1.211
1.2GluCys: 1.2 ± 0.839
0.6GluAsp: 0.6 ± 0.493
3.001GluGlu: 3.001 ± 1.375
3.601GluPhe: 3.601 ± 1.324
2.401GluGly: 2.401 ± 0.962
1.2GluHis: 1.2 ± 0.807
1.2GluIle: 1.2 ± 0.839
1.2GluLys: 1.2 ± 0.721
4.202GluLeu: 4.202 ± 1.453
0.6GluMet: 0.6 ± 0.523
3.001GluAsn: 3.001 ± 1.618
1.801GluPro: 1.801 ± 0.814
1.2GluGln: 1.2 ± 1.107
0.0GluArg: 0.0 ± 0.0
2.401GluSer: 2.401 ± 1.219
2.401GluThr: 2.401 ± 1.124
4.202GluVal: 4.202 ± 1.504
1.2GluTrp: 1.2 ± 0.671
1.2GluTyr: 1.2 ± 1.045
0.0GluXaa: 0.0 ± 0.0
Phe
1.2PheAla: 1.2 ± 0.604
1.2PheCys: 1.2 ± 0.711
2.401PheAsp: 2.401 ± 0.799
1.2PheGlu: 1.2 ± 0.611
0.0PhePhe: 0.0 ± 0.0
1.2PheGly: 1.2 ± 0.706
1.801PheHis: 1.801 ± 1.138
1.2PheIle: 1.2 ± 0.721
3.601PheLys: 3.601 ± 1.471
3.001PheLeu: 3.001 ± 1.73
1.801PheMet: 1.801 ± 0.762
2.401PheAsn: 2.401 ± 1.239
1.2PhePro: 1.2 ± 0.781
3.001PheGln: 3.001 ± 0.947
3.601PheArg: 3.601 ± 1.435
3.001PheSer: 3.001 ± 1.498
1.801PheThr: 1.801 ± 0.848
1.2PheVal: 1.2 ± 0.987
1.2PheTrp: 1.2 ± 0.646
2.401PheTyr: 2.401 ± 1.822
0.0PheXaa: 0.0 ± 0.0
Gly
4.202GlyAla: 4.202 ± 1.98
1.801GlyCys: 1.801 ± 0.959
3.001GlyAsp: 3.001 ± 1.123
3.001GlyGlu: 3.001 ± 1.053
1.2GlyPhe: 1.2 ± 1.226
3.601GlyGly: 3.601 ± 1.423
2.401GlyHis: 2.401 ± 1.124
1.801GlyIle: 1.801 ± 0.648
4.202GlyLys: 4.202 ± 1.718
2.401GlyLeu: 2.401 ± 1.002
1.2GlyMet: 1.2 ± 0.863
1.801GlyAsn: 1.801 ± 0.941
6.603GlyPro: 6.603 ± 1.209
4.202GlyGln: 4.202 ± 1.166
3.601GlyArg: 3.601 ± 1.48
4.802GlySer: 4.802 ± 2.206
4.202GlyThr: 4.202 ± 2.069
2.401GlyVal: 2.401 ± 1.356
0.0GlyTrp: 0.0 ± 0.0
0.6GlyTyr: 0.6 ± 0.634
0.0GlyXaa: 0.0 ± 0.0
His
1.2HisAla: 1.2 ± 0.798
1.801HisCys: 1.801 ± 0.845
2.401HisAsp: 2.401 ± 1.363
1.2HisGlu: 1.2 ± 0.671
2.401HisPhe: 2.401 ± 1.095
2.401HisGly: 2.401 ± 1.214
0.6HisHis: 0.6 ± 0.613
2.401HisIle: 2.401 ± 1.547
1.2HisLys: 1.2 ± 0.839
1.2HisLeu: 1.2 ± 0.987
0.6HisMet: 0.6 ± 0.56
3.601HisAsn: 3.601 ± 1.26
0.6HisPro: 0.6 ± 0.493
0.6HisGln: 0.6 ± 0.554
3.001HisArg: 3.001 ± 1.657
1.801HisSer: 1.801 ± 0.947
3.601HisThr: 3.601 ± 1.877
4.202HisVal: 4.202 ± 0.892
0.6HisTrp: 0.6 ± 0.749
1.801HisTyr: 1.801 ± 0.603
0.0HisXaa: 0.0 ± 0.0
Ile
1.2IleAla: 1.2 ± 0.706
0.6IleCys: 0.6 ± 0.554
4.802IleAsp: 4.802 ± 2.123
3.601IleGlu: 3.601 ± 1.268
2.401IlePhe: 2.401 ± 0.993
1.2IleGly: 1.2 ± 1.045
0.6IleHis: 0.6 ± 0.523
4.202IleIle: 4.202 ± 1.513
4.202IleLys: 4.202 ± 1.08
2.401IleLeu: 2.401 ± 1.149
0.0IleMet: 0.0 ± 0.0
3.601IleAsn: 3.601 ± 1.385
1.801IlePro: 1.801 ± 0.813
4.202IleGln: 4.202 ± 1.414
4.802IleArg: 4.802 ± 2.001
7.203IleSer: 7.203 ± 2.51
3.601IleThr: 3.601 ± 2.074
1.801IleVal: 1.801 ± 1.099
1.2IleTrp: 1.2 ± 1.31
0.6IleTyr: 0.6 ± 0.554
0.0IleXaa: 0.0 ± 0.0
Lys
1.801LysAla: 1.801 ± 1.075
1.2LysCys: 1.2 ± 0.807
3.001LysAsp: 3.001 ± 1.311
1.2LysGlu: 1.2 ± 0.611
3.001LysPhe: 3.001 ± 0.989
1.2LysGly: 1.2 ± 0.671
1.2LysHis: 1.2 ± 0.721
1.801LysIle: 1.801 ± 0.974
1.801LysLys: 1.801 ± 0.648
1.2LysLeu: 1.2 ± 0.646
0.0LysMet: 0.0 ± 0.0
4.202LysAsn: 4.202 ± 1.395
2.401LysPro: 2.401 ± 0.717
3.601LysGln: 3.601 ± 0.909
3.001LysArg: 3.001 ± 1.324
3.601LysSer: 3.601 ± 1.804
2.401LysThr: 2.401 ± 0.802
6.603LysVal: 6.603 ± 2.085
0.0LysTrp: 0.0 ± 0.0
3.601LysTyr: 3.601 ± 1.589
0.0LysXaa: 0.0 ± 0.0
Leu
2.401LeuAla: 2.401 ± 0.692
2.401LeuCys: 2.401 ± 0.893
4.202LeuAsp: 4.202 ± 1.529
4.202LeuGlu: 4.202 ± 1.363
3.601LeuPhe: 3.601 ± 1.092
6.603LeuGly: 6.603 ± 1.544
1.801LeuHis: 1.801 ± 1.048
2.401LeuIle: 2.401 ± 1.657
3.001LeuLys: 3.001 ± 1.475
2.401LeuLeu: 2.401 ± 1.157
0.0LeuMet: 0.0 ± 0.0
4.802LeuAsn: 4.802 ± 1.313
0.6LeuPro: 0.6 ± 0.613
2.401LeuGln: 2.401 ± 1.04
7.803LeuArg: 7.803 ± 2.035
5.402LeuSer: 5.402 ± 1.531
6.603LeuThr: 6.603 ± 1.888
4.202LeuVal: 4.202 ± 1.815
0.6LeuTrp: 0.6 ± 0.554
3.601LeuTyr: 3.601 ± 1.473
0.0LeuXaa: 0.0 ± 0.0
Met
1.801MetAla: 1.801 ± 1.056
0.6MetCys: 0.6 ± 0.749
1.801MetAsp: 1.801 ± 1.186
0.6MetGlu: 0.6 ± 0.523
0.6MetPhe: 0.6 ± 0.554
2.401MetGly: 2.401 ± 1.015
0.6MetHis: 0.6 ± 0.523
0.0MetIle: 0.0 ± 0.0
0.6MetLys: 0.6 ± 0.56
3.601MetLeu: 3.601 ± 2.082
0.0MetMet: 0.0 ± 0.0
0.6MetAsn: 0.6 ± 0.655
1.2MetPro: 1.2 ± 1.12
0.0MetGln: 0.0 ± 0.0
1.2MetArg: 1.2 ± 0.706
1.801MetSer: 1.801 ± 1.168
0.0MetThr: 0.0 ± 0.0
0.0MetVal: 0.0 ± 0.0
1.2MetTrp: 1.2 ± 0.778
3.601MetTyr: 3.601 ± 1.714
0.0MetXaa: 0.0 ± 0.0
Asn
3.001AsnAla: 3.001 ± 0.849
0.6AsnCys: 0.6 ± 0.523
4.202AsnAsp: 4.202 ± 0.788
1.801AsnGlu: 1.801 ± 0.814
0.6AsnPhe: 0.6 ± 0.554
3.601AsnGly: 3.601 ± 1.248
6.603AsnHis: 6.603 ± 2.929
3.001AsnIle: 3.001 ± 0.849
0.6AsnLys: 0.6 ± 0.493
3.001AsnLeu: 3.001 ± 1.384
1.801AsnMet: 1.801 ± 1.157
6.603AsnAsn: 6.603 ± 1.871
3.001AsnPro: 3.001 ± 0.9
1.801AsnGln: 1.801 ± 0.89
3.001AsnArg: 3.001 ± 0.745
3.601AsnSer: 3.601 ± 1.817
6.002AsnThr: 6.002 ± 1.439
4.202AsnVal: 4.202 ± 2.005
0.6AsnTrp: 0.6 ± 0.493
1.801AsnTyr: 1.801 ± 1.138
0.0AsnXaa: 0.0 ± 0.0
Pro
3.001ProAla: 3.001 ± 1.16
1.2ProCys: 1.2 ± 0.798
1.801ProAsp: 1.801 ± 0.988
2.401ProGlu: 2.401 ± 1.111
1.2ProPhe: 1.2 ± 0.807
4.802ProGly: 4.802 ± 0.872
3.601ProHis: 3.601 ± 1.933
2.401ProIle: 2.401 ± 1.16
3.001ProLys: 3.001 ± 1.563
3.601ProLeu: 3.601 ± 1.054
2.401ProMet: 2.401 ± 1.137
2.401ProAsn: 2.401 ± 1.005
1.2ProPro: 1.2 ± 0.721
1.801ProGln: 1.801 ± 1.04
4.802ProArg: 4.802 ± 1.36
5.402ProSer: 5.402 ± 1.784
4.202ProThr: 4.202 ± 1.445
5.402ProVal: 5.402 ± 1.166
0.6ProTrp: 0.6 ± 0.523
3.601ProTyr: 3.601 ± 1.109
0.0ProXaa: 0.0 ± 0.0
Gln
3.601GlnAla: 3.601 ± 1.165
0.0GlnCys: 0.0 ± 0.0
1.2GlnAsp: 1.2 ± 0.987
1.2GlnGlu: 1.2 ± 0.611
3.601GlnPhe: 3.601 ± 1.493
3.001GlnGly: 3.001 ± 1.254
1.801GlnHis: 1.801 ± 1.365
2.401GlnIle: 2.401 ± 1.324
0.0GlnLys: 0.0 ± 0.0
2.401GlnLeu: 2.401 ± 1.006
0.6GlnMet: 0.6 ± 0.613
1.2GlnAsn: 1.2 ± 0.8
2.401GlnPro: 2.401 ± 1.419
3.001GlnGln: 3.001 ± 0.911
2.401GlnArg: 2.401 ± 0.546
3.601GlnSer: 3.601 ± 1.204
3.001GlnThr: 3.001 ± 0.911
3.601GlnVal: 3.601 ± 1.468
0.0GlnTrp: 0.0 ± 0.0
1.2GlnTyr: 1.2 ± 0.706
0.0GlnXaa: 0.0 ± 0.0
Arg
1.801ArgAla: 1.801 ± 0.813
1.2ArgCys: 1.2 ± 0.781
3.601ArgAsp: 3.601 ± 1.205
2.401ArgGlu: 2.401 ± 1.799
4.202ArgPhe: 4.202 ± 1.413
4.202ArgGly: 4.202 ± 2.167
3.001ArgHis: 3.001 ± 1.236
4.802ArgIle: 4.802 ± 1.175
3.001ArgLys: 3.001 ± 1.635
7.803ArgLeu: 7.803 ± 1.231
1.2ArgMet: 1.2 ± 0.835
1.2ArgAsn: 1.2 ± 0.646
6.603ArgPro: 6.603 ± 1.697
0.6ArgGln: 0.6 ± 0.634
8.403ArgArg: 8.403 ± 2.97
6.002ArgSer: 6.002 ± 1.669
4.202ArgThr: 4.202 ± 2.066
9.004ArgVal: 9.004 ± 2.36
0.0ArgTrp: 0.0 ± 0.0
1.801ArgTyr: 1.801 ± 1.138
0.0ArgXaa: 0.0 ± 0.0
Ser
8.403SerAla: 8.403 ± 2.684
0.6SerCys: 0.6 ± 0.56
4.802SerAsp: 4.802 ± 1.279
3.001SerGlu: 3.001 ± 1.437
1.801SerPhe: 1.801 ± 0.849
2.401SerGly: 2.401 ± 1.295
1.2SerHis: 1.2 ± 0.915
4.802SerIle: 4.802 ± 1.506
6.002SerLys: 6.002 ± 1.012
3.601SerLeu: 3.601 ± 1.545
1.801SerMet: 1.801 ± 0.964
6.603SerAsn: 6.603 ± 1.764
8.403SerPro: 8.403 ± 1.639
2.401SerGln: 2.401 ± 1.893
6.603SerArg: 6.603 ± 1.731
12.605SerSer: 12.605 ± 3.203
7.803SerThr: 7.803 ± 2.253
3.601SerVal: 3.601 ± 0.904
0.6SerTrp: 0.6 ± 0.56
3.001SerTyr: 3.001 ± 0.872
0.0SerXaa: 0.0 ± 0.0
Thr
3.001ThrAla: 3.001 ± 0.989
1.2ThrCys: 1.2 ± 0.732
1.801ThrAsp: 1.801 ± 1.498
3.601ThrGlu: 3.601 ± 1.047
1.2ThrPhe: 1.2 ± 0.839
6.603ThrGly: 6.603 ± 1.116
4.202ThrHis: 4.202 ± 1.508
4.802ThrIle: 4.802 ± 0.817
2.401ThrLys: 2.401 ± 1.084
4.802ThrLeu: 4.802 ± 1.51
1.801ThrMet: 1.801 ± 0.979
2.401ThrAsn: 2.401 ± 0.546
4.802ThrPro: 4.802 ± 1.641
2.401ThrGln: 2.401 ± 1.005
5.402ThrArg: 5.402 ± 1.465
4.802ThrSer: 4.802 ± 1.594
2.401ThrThr: 2.401 ± 0.893
6.002ThrVal: 6.002 ± 1.917
1.2ThrTrp: 1.2 ± 0.835
3.001ThrTyr: 3.001 ± 1.296
0.0ThrXaa: 0.0 ± 0.0
Val
0.6ValAla: 0.6 ± 0.523
1.801ValCys: 1.801 ± 0.999
1.801ValAsp: 1.801 ± 0.74
1.801ValGlu: 1.801 ± 1.324
3.001ValPhe: 3.001 ± 1.528
1.801ValGly: 1.801 ± 0.727
2.401ValHis: 2.401 ± 1.079
8.403ValIle: 8.403 ± 3.163
4.202ValLys: 4.202 ± 1.223
5.402ValLeu: 5.402 ± 2.473
3.001ValMet: 3.001 ± 1.458
4.802ValAsn: 4.802 ± 0.911
6.002ValPro: 6.002 ± 0.733
3.601ValGln: 3.601 ± 1.065
3.001ValArg: 3.001 ± 1.822
6.603ValSer: 6.603 ± 1.891
4.202ValThr: 4.202 ± 1.009
2.401ValVal: 2.401 ± 1.413
1.801ValTrp: 1.801 ± 0.648
3.601ValTyr: 3.601 ± 1.556
0.0ValXaa: 0.0 ± 0.0
Trp
2.401TrpAla: 2.401 ± 0.906
0.0TrpCys: 0.0 ± 0.0
0.6TrpAsp: 0.6 ± 0.634
1.2TrpGlu: 1.2 ± 0.839
0.0TrpPhe: 0.0 ± 0.0
0.6TrpGly: 0.6 ± 0.493
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.6TrpLeu: 0.6 ± 0.56
0.6TrpMet: 0.6 ± 0.554
0.6TrpAsn: 0.6 ± 0.749
0.0TrpPro: 0.0 ± 0.0
0.6TrpGln: 0.6 ± 0.493
1.2TrpArg: 1.2 ± 0.791
0.6TrpSer: 0.6 ± 0.749
1.2TrpThr: 1.2 ± 0.803
1.2TrpVal: 1.2 ± 0.642
0.0TrpTrp: 0.0 ± 0.0
1.2TrpTyr: 1.2 ± 0.642
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.401TyrAla: 2.401 ± 1.021
0.0TyrCys: 0.0 ± 0.0
1.801TyrAsp: 1.801 ± 1.218
0.6TyrGlu: 0.6 ± 0.554
2.401TyrPhe: 2.401 ± 0.717
3.001TyrGly: 3.001 ± 1.011
0.6TyrHis: 0.6 ± 0.56
3.001TyrIle: 3.001 ± 1.605
0.0TyrLys: 0.0 ± 0.0
4.802TyrLeu: 4.802 ± 1.481
1.2TyrMet: 1.2 ± 0.77
3.001TyrAsn: 3.001 ± 0.892
3.001TyrPro: 3.001 ± 1.498
1.2TyrGln: 1.2 ± 0.711
4.202TyrArg: 4.202 ± 1.579
3.001TyrSer: 3.001 ± 0.584
1.801TyrThr: 1.801 ± 0.603
4.202TyrVal: 4.202 ± 2.193
0.0TyrTrp: 0.0 ± 0.0
1.801TyrTyr: 1.801 ± 0.848
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (1667 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski