Amino acid dipepetide frequency for Hubei yanvirus-like virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.893AlaAla: 7.893 ± 2.028
1.821AlaCys: 1.821 ± 0.739
4.857AlaAsp: 4.857 ± 2.037
4.857AlaGlu: 4.857 ± 1.938
3.643AlaPhe: 3.643 ± 1.1
6.072AlaGly: 6.072 ± 1.882
1.214AlaHis: 1.214 ± 0.509
4.25AlaIle: 4.25 ± 1.708
4.25AlaLys: 4.25 ± 1.049
6.679AlaLeu: 6.679 ± 1.672
1.214AlaMet: 1.214 ± 0.63
4.857AlaAsn: 4.857 ± 0.415
9.107AlaPro: 9.107 ± 0.69
3.643AlaGln: 3.643 ± 1.746
4.857AlaArg: 4.857 ± 1.928
9.107AlaSer: 9.107 ± 0.464
7.286AlaThr: 7.286 ± 1.152
7.893AlaVal: 7.893 ± 0.831
2.429AlaTrp: 2.429 ± 0.737
2.429AlaTyr: 2.429 ± 0.969
0.0AlaXaa: 0.0 ± 0.0
Cys
1.214CysAla: 1.214 ± 0.821
0.0CysCys: 0.0 ± 0.0
0.607CysAsp: 0.607 ± 0.557
0.607CysGlu: 0.607 ± 0.411
1.214CysPhe: 1.214 ± 0.63
1.821CysGly: 1.821 ± 1.232
1.214CysHis: 1.214 ± 0.821
0.607CysIle: 0.607 ± 0.411
0.607CysLys: 0.607 ± 0.557
0.607CysLeu: 0.607 ± 0.411
0.0CysMet: 0.0 ± 0.0
1.214CysAsn: 1.214 ± 0.821
0.0CysPro: 0.0 ± 0.0
0.607CysGln: 0.607 ± 0.411
0.0CysArg: 0.0 ± 0.0
1.821CysSer: 1.821 ± 0.226
3.036CysThr: 3.036 ± 0.562
2.429CysVal: 2.429 ± 0.208
0.0CysTrp: 0.0 ± 0.0
1.214CysTyr: 1.214 ± 0.423
0.0CysXaa: 0.0 ± 0.0
Asp
5.464AspAla: 5.464 ± 0.639
1.214AspCys: 1.214 ± 0.423
3.036AspAsp: 3.036 ± 2.096
1.214AspGlu: 1.214 ± 1.114
0.0AspPhe: 0.0 ± 0.0
4.857AspGly: 4.857 ± 0.471
0.607AspHis: 0.607 ± 0.411
0.607AspIle: 0.607 ± 0.552
1.214AspLys: 1.214 ± 0.63
3.036AspLeu: 3.036 ± 0.852
0.0AspMet: 0.0 ± 0.0
0.607AspAsn: 0.607 ± 0.552
3.643AspPro: 3.643 ± 1.019
1.821AspGln: 1.821 ± 1.232
1.214AspArg: 1.214 ± 0.509
3.643AspSer: 3.643 ± 1.1
2.429AspThr: 2.429 ± 0.208
3.643AspVal: 3.643 ± 1.97
1.214AspTrp: 1.214 ± 0.423
2.429AspTyr: 2.429 ± 1.562
0.0AspXaa: 0.0 ± 0.0
Glu
6.072GluAla: 6.072 ± 1.22
1.821GluCys: 1.821 ± 0.624
1.821GluAsp: 1.821 ± 0.226
4.857GluGlu: 4.857 ± 1.928
1.821GluPhe: 1.821 ± 0.624
3.643GluGly: 3.643 ± 0.429
1.214GluHis: 1.214 ± 0.63
1.821GluIle: 1.821 ± 1.053
1.821GluLys: 1.821 ± 0.226
4.25GluLeu: 4.25 ± 1.69
1.821GluMet: 1.821 ± 0.893
1.214GluAsn: 1.214 ± 0.63
2.429GluPro: 2.429 ± 0.969
1.821GluGln: 1.821 ± 0.739
3.643GluArg: 3.643 ± 0.452
3.643GluSer: 3.643 ± 0.653
3.643GluThr: 3.643 ± 1.528
1.821GluVal: 1.821 ± 1.232
2.429GluTrp: 2.429 ± 1.081
1.821GluTyr: 1.821 ± 1.671
0.0GluXaa: 0.0 ± 0.0
Phe
2.429PheAla: 2.429 ± 1.081
0.0PheCys: 0.0 ± 0.0
2.429PheAsp: 2.429 ± 0.737
1.214PheGlu: 1.214 ± 0.423
2.429PhePhe: 2.429 ± 1.423
5.464PheGly: 5.464 ± 2.746
0.607PheHis: 0.607 ± 0.552
0.0PheIle: 0.0 ± 0.0
0.607PheLys: 0.607 ± 0.557
2.429PheLeu: 2.429 ± 1.081
0.0PheMet: 0.0 ± 0.0
1.821PheAsn: 1.821 ± 0.893
3.036PhePro: 3.036 ± 1.283
1.821PheGln: 1.821 ± 0.226
3.036PheArg: 3.036 ± 1.283
4.25PheSer: 4.25 ± 2.582
2.429PheThr: 2.429 ± 0.672
0.607PheVal: 0.607 ± 0.557
2.429PheTrp: 2.429 ± 0.737
1.821PheTyr: 1.821 ± 0.985
0.0PheXaa: 0.0 ± 0.0
Gly
4.25GlyAla: 4.25 ± 0.14
0.607GlyCys: 0.607 ± 0.411
3.643GlyAsp: 3.643 ± 1.528
1.821GlyGlu: 1.821 ± 0.739
1.214GlyPhe: 1.214 ± 1.103
6.072GlyGly: 6.072 ± 1.661
0.607GlyHis: 0.607 ± 0.411
0.607GlyIle: 0.607 ± 0.557
9.107GlyLys: 9.107 ± 1.295
6.679GlyLeu: 6.679 ± 0.899
0.607GlyMet: 0.607 ± 0.557
3.643GlyAsn: 3.643 ± 0.429
3.643GlyPro: 3.643 ± 0.653
2.429GlyGln: 2.429 ± 1.643
5.464GlyArg: 5.464 ± 0.814
4.857GlySer: 4.857 ± 1.593
5.464GlyThr: 5.464 ± 2.102
8.5GlyVal: 8.5 ± 1.555
1.214GlyTrp: 1.214 ± 0.821
3.643GlyTyr: 3.643 ± 2.511
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
1.214HisCys: 1.214 ± 0.821
1.821HisAsp: 1.821 ± 0.739
1.214HisGlu: 1.214 ± 0.423
0.607HisPhe: 0.607 ± 0.411
1.214HisGly: 1.214 ± 0.509
0.0HisHis: 0.0 ± 0.0
1.214HisIle: 1.214 ± 1.103
0.0HisLys: 0.0 ± 0.0
3.036HisLeu: 3.036 ± 0.386
0.607HisMet: 0.607 ± 0.552
0.0HisAsn: 0.0 ± 0.0
2.429HisPro: 2.429 ± 0.845
0.0HisGln: 0.0 ± 0.0
2.429HisArg: 2.429 ± 0.737
0.0HisSer: 0.0 ± 0.0
0.607HisThr: 0.607 ± 0.557
1.214HisVal: 1.214 ± 0.821
0.607HisTrp: 0.607 ± 0.557
0.607HisTyr: 0.607 ± 0.411
0.0HisXaa: 0.0 ± 0.0
Ile
3.036IleAla: 3.036 ± 1.634
1.821IleCys: 1.821 ± 0.739
0.607IleAsp: 0.607 ± 0.557
2.429IleGlu: 2.429 ± 1.562
0.607IlePhe: 0.607 ± 0.411
1.821IleGly: 1.821 ± 0.226
0.0IleHis: 0.0 ± 0.0
0.607IleIle: 0.607 ± 0.557
0.607IleLys: 0.607 ± 0.557
2.429IleLeu: 2.429 ± 0.969
1.214IleMet: 1.214 ± 0.63
1.214IleAsn: 1.214 ± 1.103
2.429IlePro: 2.429 ± 1.423
1.214IleGln: 1.214 ± 0.63
2.429IleArg: 2.429 ± 0.208
2.429IleSer: 2.429 ± 0.845
2.429IleThr: 2.429 ± 0.672
1.821IleVal: 1.821 ± 1.053
0.0IleTrp: 0.0 ± 0.0
0.607IleTyr: 0.607 ± 0.557
0.0IleXaa: 0.0 ± 0.0
Lys
4.857LysAla: 4.857 ± 1.547
0.607LysCys: 0.607 ± 0.557
1.821LysAsp: 1.821 ± 1.655
1.821LysGlu: 1.821 ± 0.226
0.0LysPhe: 0.0 ± 0.0
5.464LysGly: 5.464 ± 1.19
1.214LysHis: 1.214 ± 0.63
1.214LysIle: 1.214 ± 1.114
3.036LysLys: 3.036 ± 2.758
6.072LysLeu: 6.072 ± 2.059
1.214LysMet: 1.214 ± 0.927
0.0LysAsn: 0.0 ± 0.0
3.036LysPro: 3.036 ± 0.562
3.036LysGln: 3.036 ± 0.562
1.821LysArg: 1.821 ± 0.739
2.429LysSer: 2.429 ± 0.208
1.821LysThr: 1.821 ± 0.739
4.857LysVal: 4.857 ± 2.03
0.607LysTrp: 0.607 ± 0.557
0.607LysTyr: 0.607 ± 0.552
0.0LysXaa: 0.0 ± 0.0
Leu
9.715LeuAla: 9.715 ± 1.701
3.036LeuCys: 3.036 ± 0.61
4.857LeuAsp: 4.857 ± 0.69
6.679LeuGlu: 6.679 ± 1.312
4.857LeuPhe: 4.857 ± 2.853
4.857LeuGly: 4.857 ± 1.152
2.429LeuHis: 2.429 ± 0.845
1.821LeuIle: 1.821 ± 0.739
3.643LeuLys: 3.643 ± 0.653
4.857LeuLeu: 4.857 ± 2.037
0.0LeuMet: 0.0 ± 0.409
4.25LeuAsn: 4.25 ± 0.837
7.286LeuPro: 7.286 ± 0.279
1.214LeuGln: 1.214 ± 1.103
2.429LeuArg: 2.429 ± 0.969
5.464LeuSer: 5.464 ± 0.283
5.464LeuThr: 5.464 ± 1.809
9.107LeuVal: 9.107 ± 3.173
2.429LeuTrp: 2.429 ± 0.737
3.643LeuTyr: 3.643 ± 1.1
0.0LeuXaa: 0.0 ± 0.0
Met
1.214MetAla: 1.214 ± 0.509
1.214MetCys: 1.214 ± 0.509
0.607MetAsp: 0.607 ± 0.552
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
1.214MetGly: 1.214 ± 0.423
0.607MetHis: 0.607 ± 0.411
1.214MetIle: 1.214 ± 0.63
0.607MetLys: 0.607 ± 0.552
1.821MetLeu: 1.821 ± 1.655
0.607MetMet: 0.607 ± 0.557
0.607MetAsn: 0.607 ± 0.557
2.429MetPro: 2.429 ± 1.259
0.607MetGln: 0.607 ± 0.557
1.214MetArg: 1.214 ± 0.423
0.0MetSer: 0.0 ± 0.0
1.214MetThr: 1.214 ± 0.821
1.214MetVal: 1.214 ± 0.509
0.0MetTrp: 0.0 ± 0.0
0.607MetTyr: 0.607 ± 0.552
0.0MetXaa: 0.0 ± 0.0
Asn
7.893AsnAla: 7.893 ± 3.418
0.0AsnCys: 0.0 ± 0.0
0.0AsnAsp: 0.0 ± 0.0
0.607AsnGlu: 0.607 ± 0.411
0.607AsnPhe: 0.607 ± 0.411
1.821AsnGly: 1.821 ± 1.045
0.0AsnHis: 0.0 ± 0.0
0.607AsnIle: 0.607 ± 0.552
1.214AsnLys: 1.214 ± 0.509
2.429AsnLeu: 2.429 ± 0.672
0.0AsnMet: 0.0 ± 0.0
0.0AsnAsn: 0.0 ± 0.0
3.036AsnPro: 3.036 ± 1.351
0.607AsnGln: 0.607 ± 0.411
3.036AsnArg: 3.036 ± 1.201
3.643AsnSer: 3.643 ± 1.268
0.607AsnThr: 0.607 ± 0.411
3.036AsnVal: 3.036 ± 1.283
0.0AsnTrp: 0.0 ± 0.0
0.607AsnTyr: 0.607 ± 0.552
0.0AsnXaa: 0.0 ± 0.0
Pro
4.25ProAla: 4.25 ± 0.14
0.0ProCys: 0.0 ± 0.0
2.429ProAsp: 2.429 ± 0.845
7.893ProGlu: 7.893 ± 2.41
1.821ProPhe: 1.821 ± 0.893
5.464ProGly: 5.464 ± 3.696
1.821ProHis: 1.821 ± 0.985
3.643ProIle: 3.643 ± 0.929
3.643ProLys: 3.643 ± 0.929
7.893ProLeu: 7.893 ± 1.128
0.607ProMet: 0.607 ± 0.411
1.821ProAsn: 1.821 ± 0.624
10.322ProPro: 10.322 ± 6.322
2.429ProGln: 2.429 ± 1.423
3.643ProArg: 3.643 ± 1.852
5.464ProSer: 5.464 ± 1.19
4.25ProThr: 4.25 ± 0.746
5.464ProVal: 5.464 ± 1.016
0.0ProTrp: 0.0 ± 0.0
4.857ProTyr: 4.857 ± 1.868
0.0ProXaa: 0.0 ± 0.0
Gln
4.857GlnAla: 4.857 ± 0.69
0.607GlnCys: 0.607 ± 0.557
0.607GlnAsp: 0.607 ± 0.411
2.429GlnGlu: 2.429 ± 0.845
0.607GlnPhe: 0.607 ± 0.557
3.036GlnGly: 3.036 ± 0.61
1.214GlnHis: 1.214 ± 0.423
1.821GlnIle: 1.821 ± 0.226
1.821GlnLys: 1.821 ± 0.624
3.036GlnLeu: 3.036 ± 0.852
0.0GlnMet: 0.0 ± 0.0
1.821GlnAsn: 1.821 ± 0.893
3.036GlnPro: 3.036 ± 1.351
2.429GlnGln: 2.429 ± 0.208
1.214GlnArg: 1.214 ± 0.509
0.0GlnSer: 0.0 ± 0.0
2.429GlnThr: 2.429 ± 0.969
4.25GlnVal: 4.25 ± 1.806
0.607GlnTrp: 0.607 ± 0.411
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
6.072ArgAla: 6.072 ± 2.059
1.214ArgCys: 1.214 ± 0.423
3.036ArgAsp: 3.036 ± 0.562
3.036ArgGlu: 3.036 ± 1.201
2.429ArgPhe: 2.429 ± 1.259
4.25ArgGly: 4.25 ± 2.25
0.607ArgHis: 0.607 ± 0.411
1.821ArgIle: 1.821 ± 0.226
1.821ArgLys: 1.821 ± 0.985
6.072ArgLeu: 6.072 ± 1.802
1.821ArgMet: 1.821 ± 0.739
1.821ArgAsn: 1.821 ± 0.624
5.464ArgPro: 5.464 ± 1.047
2.429ArgGln: 2.429 ± 1.018
3.643ArgArg: 3.643 ± 1.97
4.25ArgSer: 4.25 ± 0.837
1.821ArgThr: 1.821 ± 0.624
3.036ArgVal: 3.036 ± 1.201
0.0ArgTrp: 0.0 ± 0.0
1.214ArgTyr: 1.214 ± 0.509
0.0ArgXaa: 0.0 ± 0.0
Ser
6.072SerAla: 6.072 ± 1.026
1.214SerCys: 1.214 ± 0.821
3.036SerAsp: 3.036 ± 1.209
2.429SerGlu: 2.429 ± 1.259
6.072SerPhe: 6.072 ± 1.026
4.25SerGly: 4.25 ± 0.777
1.214SerHis: 1.214 ± 0.509
4.25SerIle: 4.25 ± 0.14
2.429SerLys: 2.429 ± 1.423
8.5SerLeu: 8.5 ± 2.543
2.429SerMet: 2.429 ± 0.845
2.429SerAsn: 2.429 ± 0.845
2.429SerPro: 2.429 ± 0.737
1.821SerGln: 1.821 ± 0.624
2.429SerArg: 2.429 ± 1.018
10.322SerSer: 10.322 ± 1.269
6.072SerThr: 6.072 ± 1.566
5.464SerVal: 5.464 ± 1.667
3.036SerTrp: 3.036 ± 0.562
0.607SerTyr: 0.607 ± 0.411
0.0SerXaa: 0.0 ± 0.0
Thr
6.679ThrAla: 6.679 ± 2.117
0.0ThrCys: 0.0 ± 0.0
1.821ThrAsp: 1.821 ± 0.624
1.214ThrGlu: 1.214 ± 0.509
3.036ThrPhe: 3.036 ± 1.209
1.821ThrGly: 1.821 ± 0.624
1.214ThrHis: 1.214 ± 0.509
2.429ThrIle: 2.429 ± 0.208
4.857ThrLys: 4.857 ± 1.593
6.679ThrLeu: 6.679 ± 0.899
1.214ThrMet: 1.214 ± 1.114
0.0ThrAsn: 0.0 ± 0.0
4.25ThrPro: 4.25 ± 0.777
1.214ThrGln: 1.214 ± 0.423
4.857ThrArg: 4.857 ± 1.125
3.643ThrSer: 3.643 ± 2.613
6.072ThrThr: 6.072 ± 2.567
5.464ThrVal: 5.464 ± 0.814
3.036ThrTrp: 3.036 ± 0.562
3.036ThrTyr: 3.036 ± 1.209
0.0ThrXaa: 0.0 ± 0.0
Val
10.322ValAla: 10.322 ± 1.78
1.821ValCys: 1.821 ± 0.739
3.036ValAsp: 3.036 ± 1.466
5.464ValGlu: 5.464 ± 2.216
3.643ValPhe: 3.643 ± 0.429
5.464ValGly: 5.464 ± 1.016
0.607ValHis: 0.607 ± 0.552
0.0ValIle: 0.0 ± 0.0
2.429ValLys: 2.429 ± 0.208
9.107ValLeu: 9.107 ± 1.295
1.214ValMet: 1.214 ± 0.473
1.821ValAsn: 1.821 ± 0.226
4.25ValPro: 4.25 ± 0.935
3.643ValGln: 3.643 ± 1.019
5.464ValArg: 5.464 ± 1.495
3.643ValSer: 3.643 ± 0.929
3.036ValThr: 3.036 ± 2.075
5.464ValVal: 5.464 ± 2.25
4.25ValTrp: 4.25 ± 1.69
2.429ValTyr: 2.429 ± 0.969
0.0ValXaa: 0.0 ± 0.0
Trp
3.643TrpAla: 3.643 ± 1.019
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
2.429TrpGlu: 2.429 ± 0.737
0.607TrpPhe: 0.607 ± 0.557
3.036TrpGly: 3.036 ± 0.61
0.607TrpHis: 0.607 ± 0.411
0.607TrpIle: 0.607 ± 0.557
1.214TrpLys: 1.214 ± 0.509
2.429TrpLeu: 2.429 ± 0.737
1.214TrpMet: 1.214 ± 0.509
0.607TrpAsn: 0.607 ± 0.552
0.607TrpPro: 0.607 ± 0.411
0.607TrpGln: 0.607 ± 0.557
1.821TrpArg: 1.821 ± 0.985
3.643TrpSer: 3.643 ± 1.528
1.214TrpThr: 1.214 ± 0.509
0.607TrpVal: 0.607 ± 0.552
0.607TrpTrp: 0.607 ± 0.411
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.429TyrAla: 2.429 ± 0.208
0.607TyrCys: 0.607 ± 0.552
1.821TyrAsp: 1.821 ± 0.226
1.214TyrGlu: 1.214 ± 0.509
3.643TyrPhe: 3.643 ± 0.452
2.429TyrGly: 2.429 ± 0.845
1.821TyrHis: 1.821 ± 0.893
0.607TyrIle: 0.607 ± 0.552
0.607TyrLys: 0.607 ± 0.557
0.607TyrLeu: 0.607 ± 0.557
0.607TyrMet: 0.607 ± 0.552
0.0TyrAsn: 0.0 ± 0.0
4.857TyrPro: 4.857 ± 0.415
2.429TyrGln: 2.429 ± 1.259
1.214TyrArg: 1.214 ± 0.509
4.25TyrSer: 4.25 ± 1.771
1.214TyrThr: 1.214 ± 0.423
1.214TyrVal: 1.214 ± 0.63
0.607TyrTrp: 0.607 ± 0.557
2.429TyrTyr: 2.429 ± 1.423
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1648 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski