Amino acid dipepetide frequency for Alteraurantiacibacter aquimixticola

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	16.2AlaAla: 16.2 ± 0.219	1.135AlaCys: 1.135 ± 0.039	7.325AlaAsp: 7.325 ± 0.105	8.647AlaGlu: 8.647 ± 0.133	4.205AlaPhe: 4.205 ± 0.068	10.734AlaGly: 10.734 ± 0.124	2.162AlaHis: 2.162 ± 0.051	6.572AlaIle: 6.572 ± 0.095	3.783AlaLys: 3.783 ± 0.09	12.985AlaLeu: 12.985 ± 0.154	4.094AlaMet: 4.094 ± 0.075	3.391AlaAsn: 3.391 ± 0.065	5.565AlaPro: 5.565 ± 0.085	4.42AlaGln: 4.42 ± 0.063	8.264AlaArg: 8.264 ± 0.127	6.601AlaSer: 6.601 ± 0.09	5.924AlaThr: 5.924 ± 0.101	7.814AlaVal: 7.814 ± 0.11	1.55AlaTrp: 1.55 ± 0.041	2.505AlaTyr: 2.505 ± 0.058	0.002AlaXaa: 0.002 ± 0.001
Cys	1.009CysAla: 1.009 ± 0.036	0.1CysCys: 0.1 ± 0.01	0.596CysAsp: 0.596 ± 0.026	0.558CysGlu: 0.558 ± 0.025	0.3CysPhe: 0.3 ± 0.018	0.937CysGly: 0.937 ± 0.037	0.257CysHis: 0.257 ± 0.022	0.355CysIle: 0.355 ± 0.018	0.158CysLys: 0.158 ± 0.013	0.739CysLeu: 0.739 ± 0.031	0.161CysMet: 0.161 ± 0.014	0.218CysAsn: 0.218 ± 0.015	0.437CysPro: 0.437 ± 0.017	0.228CysGln: 0.228 ± 0.014	0.576CysArg: 0.576 ± 0.026	0.543CysSer: 0.543 ± 0.024	0.437CysThr: 0.437 ± 0.021	0.59CysVal: 0.59 ± 0.024	0.12CysTrp: 0.12 ± 0.01	0.182CysTyr: 0.182 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	7.461AspAla: 7.461 ± 0.106	0.581AspCys: 0.581 ± 0.027	3.555AspAsp: 3.555 ± 0.098	4.171AspGlu: 4.171 ± 0.073	2.469AspPhe: 2.469 ± 0.065	6.221AspGly: 6.221 ± 0.154	1.362AspHis: 1.362 ± 0.037	3.199AspIle: 3.199 ± 0.067	1.707AspLys: 1.707 ± 0.045	5.707AspLeu: 5.707 ± 0.096	1.635AspMet: 1.635 ± 0.039	1.684AspAsn: 1.684 ± 0.047	3.976AspPro: 3.976 ± 0.064	1.764AspGln: 1.764 ± 0.048	4.424AspArg: 4.424 ± 0.073	2.63AspSer: 2.63 ± 0.053	2.804AspThr: 2.804 ± 0.084	4.18AspVal: 4.18 ± 0.082	1.202AspTrp: 1.202 ± 0.037	1.74AspTyr: 1.74 ± 0.046	0.0AspXaa: 0.0 ± 0.0
Glu	8.683GluAla: 8.683 ± 0.115	0.435GluCys: 0.435 ± 0.022	4.115GluAsp: 4.115 ± 0.083	5.169GluGlu: 5.169 ± 0.116	2.029GluPhe: 2.029 ± 0.05	5.85GluGly: 5.85 ± 0.085	1.305GluHis: 1.305 ± 0.04	3.299GluIle: 3.299 ± 0.06	2.318GluLys: 2.318 ± 0.05	6.207GluLeu: 6.207 ± 0.086	1.831GluMet: 1.831 ± 0.05	1.761GluAsn: 1.761 ± 0.044	2.91GluPro: 2.91 ± 0.068	2.491GluGln: 2.491 ± 0.052	5.118GluArg: 5.118 ± 0.082	2.745GluSer: 2.745 ± 0.051	3.355GluThr: 3.355 ± 0.057	4.457GluVal: 4.457 ± 0.074	0.969GluTrp: 0.969 ± 0.029	1.335GluTyr: 1.335 ± 0.041	0.0GluXaa: 0.0 ± 0.0
Phe	5.026PheAla: 5.026 ± 0.077	0.353PheCys: 0.353 ± 0.02	2.951PheAsp: 2.951 ± 0.064	2.258PheGlu: 2.258 ± 0.05	1.308PhePhe: 1.308 ± 0.039	3.723PheGly: 3.723 ± 0.073	0.731PheHis: 0.731 ± 0.024	1.604PheIle: 1.604 ± 0.044	0.789PheLys: 0.789 ± 0.026	3.147PheLeu: 3.147 ± 0.065	0.816PheMet: 0.816 ± 0.031	1.108PheAsn: 1.108 ± 0.039	1.589PhePro: 1.589 ± 0.038	0.895PheGln: 0.895 ± 0.03	2.128PheArg: 2.128 ± 0.046	2.11PheSer: 2.11 ± 0.049	2.203PheThr: 2.203 ± 0.054	2.595PheVal: 2.595 ± 0.057	0.573PheTrp: 0.573 ± 0.026	0.981PheTyr: 0.981 ± 0.03	0.0PheXaa: 0.0 ± 0.0
Gly	9.347GlyAla: 9.347 ± 0.116	0.841GlyCys: 0.841 ± 0.03	5.246GlyAsp: 5.246 ± 0.141	6.542GlyGlu: 6.542 ± 0.085	3.656GlyPhe: 3.656 ± 0.066	8.182GlyGly: 8.182 ± 0.176	1.846GlyHis: 1.846 ± 0.043	4.591GlyIle: 4.591 ± 0.086	3.145GlyLys: 3.145 ± 0.066	8.353GlyLeu: 8.353 ± 0.105	2.611GlyMet: 2.611 ± 0.052	2.694GlyAsn: 2.694 ± 0.067	3.682GlyPro: 3.682 ± 0.065	3.012GlyGln: 3.012 ± 0.058	5.742GlyArg: 5.742 ± 0.084	5.309GlySer: 5.309 ± 0.089	4.964GlyThr: 4.964 ± 0.129	5.988GlyVal: 5.988 ± 0.075	1.703GlyTrp: 1.703 ± 0.05	2.28GlyTyr: 2.28 ± 0.053	0.001GlyXaa: 0.001 ± 0.001
His	2.193HisAla: 2.193 ± 0.048	0.248HisCys: 0.248 ± 0.015	1.193HisAsp: 1.193 ± 0.033	1.172HisGlu: 1.172 ± 0.03	0.933HisPhe: 0.933 ± 0.028	1.888HisGly: 1.888 ± 0.046	0.527HisHis: 0.527 ± 0.026	0.955HisIle: 0.955 ± 0.028	0.473HisLys: 0.473 ± 0.023	1.746HisLeu: 1.746 ± 0.045	0.481HisMet: 0.481 ± 0.023	0.468HisAsn: 0.468 ± 0.021	1.243HisPro: 1.243 ± 0.038	0.494HisGln: 0.494 ± 0.023	1.368HisArg: 1.368 ± 0.039	0.954HisSer: 0.954 ± 0.028	0.798HisThr: 0.798 ± 0.029	1.487HisVal: 1.487 ± 0.044	0.333HisTrp: 0.333 ± 0.018	0.556HisTyr: 0.556 ± 0.023	0.0HisXaa: 0.0 ± 0.0
Ile	7.433IleAla: 7.433 ± 0.094	0.48IleCys: 0.48 ± 0.022	3.73IleAsp: 3.73 ± 0.08	3.708IleGlu: 3.708 ± 0.069	1.643IlePhe: 1.643 ± 0.041	4.937IleGly: 4.937 ± 0.079	0.895IleHis: 0.895 ± 0.033	2.062IleIle: 2.062 ± 0.055	1.072IleLys: 1.072 ± 0.038	3.746IleLeu: 3.746 ± 0.061	0.977IleMet: 0.977 ± 0.036	1.359IleAsn: 1.359 ± 0.04	2.395IlePro: 2.395 ± 0.054	1.102IleGln: 1.102 ± 0.034	3.048IleArg: 3.048 ± 0.056	2.733IleSer: 2.733 ± 0.062	2.794IleThr: 2.794 ± 0.061	3.758IleVal: 3.758 ± 0.071	0.609IleTrp: 0.609 ± 0.026	1.064IleTyr: 1.064 ± 0.034	0.0IleXaa: 0.0 ± 0.0
Lys	3.63LysAla: 3.63 ± 0.084	0.158LysCys: 0.158 ± 0.012	1.569LysAsp: 1.569 ± 0.041	1.489LysGlu: 1.489 ± 0.041	0.826LysPhe: 0.826 ± 0.033	2.503LysGly: 2.503 ± 0.052	0.576LysHis: 0.576 ± 0.026	1.384LysIle: 1.384 ± 0.045	1.152LysLys: 1.152 ± 0.048	3.134LysLeu: 3.134 ± 0.065	0.718LysMet: 0.718 ± 0.025	0.661LysAsn: 0.661 ± 0.026	1.74LysPro: 1.74 ± 0.043	0.916LysGln: 0.916 ± 0.035	2.108LysArg: 2.108 ± 0.055	1.414LysSer: 1.414 ± 0.041	1.405LysThr: 1.405 ± 0.041	2.151LysVal: 2.151 ± 0.054	0.423LysTrp: 0.423 ± 0.022	0.581LysTyr: 0.581 ± 0.023	0.0LysXaa: 0.0 ± 0.0
Leu	13.871LeuAla: 13.871 ± 0.157	0.77LeuCys: 0.77 ± 0.031	6.006LeuAsp: 6.006 ± 0.089	5.987LeuGlu: 5.987 ± 0.085	3.564LeuPhe: 3.564 ± 0.058	8.129LeuGly: 8.129 ± 0.099	1.678LeuHis: 1.678 ± 0.043	4.141LeuIle: 4.141 ± 0.068	2.731LeuLys: 2.731 ± 0.067	9.277LeuLeu: 9.277 ± 0.152	2.048LeuMet: 2.048 ± 0.056	2.337LeuAsn: 2.337 ± 0.056	5.555LeuPro: 5.555 ± 0.086	2.727LeuGln: 2.727 ± 0.052	6.517LeuArg: 6.517 ± 0.094	5.828LeuSer: 5.828 ± 0.074	5.327LeuThr: 5.327 ± 0.076	7.369LeuVal: 7.369 ± 0.086	1.155LeuTrp: 1.155 ± 0.035	1.897LeuTyr: 1.897 ± 0.04	0.001LeuXaa: 0.001 ± 0.001
Met	3.465MetAla: 3.465 ± 0.068	0.172MetCys: 0.172 ± 0.014	1.378MetAsp: 1.378 ± 0.04	1.447MetGlu: 1.447 ± 0.036	0.745MetPhe: 0.745 ± 0.027	2.096MetGly: 2.096 ± 0.048	0.464MetHis: 0.464 ± 0.022	1.278MetIle: 1.278 ± 0.037	0.899MetLys: 0.899 ± 0.034	2.699MetLeu: 2.699 ± 0.059	0.661MetMet: 0.661 ± 0.03	0.725MetAsn: 0.725 ± 0.026	1.517MetPro: 1.517 ± 0.036	0.902MetGln: 0.902 ± 0.03	1.924MetArg: 1.924 ± 0.051	1.579MetSer: 1.579 ± 0.041	1.601MetThr: 1.601 ± 0.037	1.829MetVal: 1.829 ± 0.039	0.285MetTrp: 0.285 ± 0.019	0.292MetTyr: 0.292 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	3.309AsnAla: 3.309 ± 0.072	0.286AsnCys: 0.286 ± 0.017	1.556AsnAsp: 1.556 ± 0.084	1.353AsnGlu: 1.353 ± 0.036	1.068AsnPhe: 1.068 ± 0.038	2.672AsnGly: 2.672 ± 0.068	0.476AsnHis: 0.476 ± 0.022	1.401AsnIle: 1.401 ± 0.042	0.596AsnLys: 0.596 ± 0.024	2.571AsnLeu: 2.571 ± 0.054	0.652AsnMet: 0.652 ± 0.026	0.759AsnAsn: 0.759 ± 0.033	1.883AsnPro: 1.883 ± 0.041	0.715AsnGln: 0.715 ± 0.028	1.882AsnArg: 1.882 ± 0.046	1.493AsnSer: 1.493 ± 0.038	1.293AsnThr: 1.293 ± 0.039	2.048AsnVal: 2.048 ± 0.051	0.479AsnTrp: 0.479 ± 0.023	0.745AsnTyr: 0.745 ± 0.029	0.0AsnXaa: 0.0 ± 0.0
Pro	6.426ProAla: 6.426 ± 0.101	0.329ProCys: 0.329 ± 0.017	3.879ProAsp: 3.879 ± 0.064	4.199ProGlu: 4.199 ± 0.071	1.968ProPhe: 1.968 ± 0.05	4.607ProGly: 4.607 ± 0.077	0.979ProHis: 0.979 ± 0.034	2.27ProIle: 2.27 ± 0.049	1.258ProLys: 1.258 ± 0.036	4.697ProLeu: 4.697 ± 0.067	1.191ProMet: 1.191 ± 0.028	1.248ProAsn: 1.248 ± 0.042	2.625ProPro: 2.625 ± 0.082	1.876ProGln: 1.876 ± 0.047	2.819ProArg: 2.819 ± 0.059	2.541ProSer: 2.541 ± 0.044	2.408ProThr: 2.408 ± 0.055	4.29ProVal: 4.29 ± 0.074	0.657ProTrp: 0.657 ± 0.023	1.103ProTyr: 1.103 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	4.019GlnAla: 4.019 ± 0.065	0.262GlnCys: 0.262 ± 0.018	1.667GlnAsp: 1.667 ± 0.043	1.713GlnGlu: 1.713 ± 0.044	1.217GlnPhe: 1.217 ± 0.036	2.61GlnGly: 2.61 ± 0.055	0.624GlnHis: 0.624 ± 0.021	1.616GlnIle: 1.616 ± 0.046	0.754GlnLys: 0.754 ± 0.03	3.452GlnLeu: 3.452 ± 0.061	0.92GlnMet: 0.92 ± 0.03	0.729GlnAsn: 0.729 ± 0.029	1.725GlnPro: 1.725 ± 0.044	1.29GlnGln: 1.29 ± 0.04	2.412GlnArg: 2.412 ± 0.051	1.731GlnSer: 1.731 ± 0.038	1.482GlnThr: 1.482 ± 0.036	2.528GlnVal: 2.528 ± 0.058	0.47GlnTrp: 0.47 ± 0.021	0.712GlnTyr: 0.712 ± 0.027	0.0GlnXaa: 0.0 ± 0.0
Arg	7.317ArgAla: 7.317 ± 0.095	0.495ArgCys: 0.495 ± 0.022	4.182ArgAsp: 4.182 ± 0.072	4.789ArgGlu: 4.789 ± 0.082	2.879ArgPhe: 2.879 ± 0.057	4.818ArgGly: 4.818 ± 0.082	1.526ArgHis: 1.526 ± 0.043	3.889ArgIle: 3.889 ± 0.066	2.254ArgLys: 2.254 ± 0.045	7.189ArgLeu: 7.189 ± 0.117	1.961ArgMet: 1.961 ± 0.048	1.992ArgAsn: 1.992 ± 0.044	3.075ArgPro: 3.075 ± 0.056	2.48ArgGln: 2.48 ± 0.049	4.985ArgArg: 4.985 ± 0.102	3.41ArgSer: 3.41 ± 0.058	2.989ArgThr: 2.989 ± 0.057	4.433ArgVal: 4.433 ± 0.064	1.071ArgTrp: 1.071 ± 0.03	1.722ArgTyr: 1.722 ± 0.046	0.0ArgXaa: 0.0 ± 0.0
Ser	6.237SerAla: 6.237 ± 0.09	0.492SerCys: 0.492 ± 0.022	3.425SerAsp: 3.425 ± 0.066	3.219SerGlu: 3.219 ± 0.054	2.279SerPhe: 2.279 ± 0.058	5.679SerGly: 5.679 ± 0.103	0.978SerHis: 0.978 ± 0.034	2.643SerIle: 2.643 ± 0.052	1.352SerLys: 1.352 ± 0.036	5.258SerLeu: 5.258 ± 0.086	1.307SerMet: 1.307 ± 0.036	1.52SerAsn: 1.52 ± 0.047	2.71SerPro: 2.71 ± 0.052	1.603SerGln: 1.603 ± 0.04	3.45SerArg: 3.45 ± 0.073	3.033SerSer: 3.033 ± 0.066	2.705SerThr: 2.705 ± 0.063	3.66SerVal: 3.66 ± 0.065	0.897SerTrp: 0.897 ± 0.028	1.434SerTyr: 1.434 ± 0.044	0.0SerXaa: 0.0 ± 0.0
Thr	5.774ThrAla: 5.774 ± 0.094	0.439ThrCys: 0.439 ± 0.023	3.015ThrAsp: 3.015 ± 0.062	2.667ThrGlu: 2.667 ± 0.055	1.874ThrPhe: 1.874 ± 0.046	5.574ThrGly: 5.574 ± 0.122	0.958ThrHis: 0.958 ± 0.034	2.952ThrIle: 2.952 ± 0.066	1.198ThrLys: 1.198 ± 0.032	5.193ThrLeu: 5.193 ± 0.073	1.22ThrMet: 1.22 ± 0.033	1.435ThrAsn: 1.435 ± 0.044	3.13ThrPro: 3.13 ± 0.066	1.499ThrGln: 1.499 ± 0.044	3.2ThrArg: 3.2 ± 0.061	2.876ThrSer: 2.876 ± 0.064	2.683ThrThr: 2.683 ± 0.066	3.979ThrVal: 3.979 ± 0.075	0.607ThrTrp: 0.607 ± 0.024	1.318ThrTyr: 1.318 ± 0.039	0.0ThrXaa: 0.0 ± 0.0
Val	8.522ValAla: 8.522 ± 0.104	0.561ValCys: 0.561 ± 0.026	4.61ValAsp: 4.61 ± 0.076	5.157ValGlu: 5.157 ± 0.089	2.339ValPhe: 2.339 ± 0.049	5.442ValGly: 5.442 ± 0.079	1.286ValHis: 1.286 ± 0.037	3.762ValIle: 3.762 ± 0.064	1.92ValLys: 1.92 ± 0.048	6.92ValLeu: 6.92 ± 0.092	1.799ValMet: 1.799 ± 0.044	2.003ValAsn: 2.003 ± 0.052	3.817ValPro: 3.817 ± 0.071	2.111ValGln: 2.111 ± 0.042	4.393ValArg: 4.393 ± 0.077	4.073ValSer: 4.073 ± 0.069	4.564ValThr: 4.564 ± 0.084	5.221ValVal: 5.221 ± 0.07	0.948ValTrp: 0.948 ± 0.031	1.33ValTyr: 1.33 ± 0.035	0.001ValXaa: 0.001 ± 0.001
Trp	1.351TrpAla: 1.351 ± 0.042	0.127TrpCys: 0.127 ± 0.011	0.827TrpAsp: 0.827 ± 0.029	0.803TrpGlu: 0.803 ± 0.026	0.627TrpPhe: 0.627 ± 0.026	1.058TrpGly: 1.058 ± 0.03	0.37TrpHis: 0.37 ± 0.018	0.658TrpIle: 0.658 ± 0.027	0.421TrpLys: 0.421 ± 0.02	1.781TrpLeu: 1.781 ± 0.044	0.399TrpMet: 0.399 ± 0.019	0.487TrpAsn: 0.487 ± 0.023	0.727TrpPro: 0.727 ± 0.031	0.713TrpGln: 0.713 ± 0.028	1.242TrpArg: 1.242 ± 0.032	0.908TrpSer: 0.908 ± 0.028	0.759TrpThr: 0.759 ± 0.025	0.866TrpVal: 0.866 ± 0.029	0.243TrpTrp: 0.243 ± 0.016	0.314TrpTyr: 0.314 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.602TyrAla: 2.602 ± 0.051	0.236TyrCys: 0.236 ± 0.014	1.646TyrAsp: 1.646 ± 0.047	1.332TyrGlu: 1.332 ± 0.039	0.958TyrPhe: 0.958 ± 0.037	2.075TyrGly: 2.075 ± 0.051	0.507TyrHis: 0.507 ± 0.021	0.916TyrIle: 0.916 ± 0.027	0.561TyrLys: 0.561 ± 0.026	2.111TyrLeu: 2.111 ± 0.045	0.476TyrMet: 0.476 ± 0.025	0.663TyrAsn: 0.663 ± 0.027	1.069TyrPro: 1.069 ± 0.033	0.693TyrGln: 0.693 ± 0.024	1.856TyrArg: 1.856 ± 0.045	1.369TyrSer: 1.369 ± 0.041	1.096TyrThr: 1.096 ± 0.04	1.537TyrVal: 1.537 ± 0.041	0.385TyrTrp: 0.385 ± 0.02	0.66TyrTyr: 0.66 ± 0.025	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.001XaaAsp: 0.001 ± 0.001	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.001XaaHis: 0.001 ± 0.001	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.002XaaGln: 0.002 ± 0.001	0.001XaaArg: 0.001 ± 0.001	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3188 proteins (1045476 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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