Amino acid dipepetide frequency for Halalkalicoccus jeotgali (strain DSM 18796 / CECT 7217 / JCM 14584 / KCTC 4019 / B3)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.479AlaAla: 11.479 ± 0.157	0.819AlaCys: 0.819 ± 0.032	7.88AlaAsp: 7.88 ± 0.111	8.503AlaGlu: 8.503 ± 0.11	4.062AlaPhe: 4.062 ± 0.059	9.707AlaGly: 9.707 ± 0.111	1.811AlaHis: 1.811 ± 0.045	5.843AlaIle: 5.843 ± 0.08	1.872AlaLys: 1.872 ± 0.046	10.882AlaLeu: 10.882 ± 0.133	2.157AlaMet: 2.157 ± 0.051	2.343AlaAsn: 2.343 ± 0.046	3.725AlaPro: 3.725 ± 0.067	2.174AlaGln: 2.174 ± 0.052	6.49AlaArg: 6.49 ± 0.087	5.342AlaSer: 5.342 ± 0.083	6.411AlaThr: 6.411 ± 0.083	9.451AlaVal: 9.451 ± 0.128	1.059AlaTrp: 1.059 ± 0.035	2.763AlaTyr: 2.763 ± 0.052	0.0AlaXaa: 0.0 ± 0.0
Cys	0.648CysAla: 0.648 ± 0.03	0.099CysCys: 0.099 ± 0.009	0.515CysAsp: 0.515 ± 0.022	0.782CysGlu: 0.782 ± 0.028	0.223CysPhe: 0.223 ± 0.015	0.906CysGly: 0.906 ± 0.035	0.186CysHis: 0.186 ± 0.015	0.297CysIle: 0.297 ± 0.017	0.125CysLys: 0.125 ± 0.011	0.615CysLeu: 0.615 ± 0.024	0.138CysMet: 0.138 ± 0.014	0.205CysAsn: 0.205 ± 0.014	0.513CysPro: 0.513 ± 0.026	0.166CysGln: 0.166 ± 0.013	0.501CysArg: 0.501 ± 0.025	0.47CysSer: 0.47 ± 0.025	0.442CysThr: 0.442 ± 0.02	0.552CysVal: 0.552 ± 0.023	0.099CysTrp: 0.099 ± 0.009	0.233CysTyr: 0.233 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	7.587AspAla: 7.587 ± 0.105	0.649AspCys: 0.649 ± 0.032	5.631AspAsp: 5.631 ± 0.101	6.997AspGlu: 6.997 ± 0.105	1.845AspPhe: 1.845 ± 0.042	6.899AspGly: 6.899 ± 0.109	1.762AspHis: 1.762 ± 0.047	2.835AspIle: 2.835 ± 0.06	0.883AspLys: 0.883 ± 0.04	7.2AspLeu: 7.2 ± 0.092	1.264AspMet: 1.264 ± 0.032	1.258AspAsn: 1.258 ± 0.04	4.747AspPro: 4.747 ± 0.085	1.547AspGln: 1.547 ± 0.042	6.153AspArg: 6.153 ± 0.092	3.816AspSer: 3.816 ± 0.066	3.787AspThr: 3.787 ± 0.071	6.41AspVal: 6.41 ± 0.083	0.942AspTrp: 0.942 ± 0.031	1.717AspTyr: 1.717 ± 0.041	0.0AspXaa: 0.0 ± 0.0
Glu	9.13GluAla: 9.13 ± 0.116	0.666GluCys: 0.666 ± 0.029	5.886GluAsp: 5.886 ± 0.08	8.199GluGlu: 8.199 ± 0.118	3.264GluPhe: 3.264 ± 0.057	6.921GluGly: 6.921 ± 0.092	2.044GluHis: 2.044 ± 0.045	4.664GluIle: 4.664 ± 0.072	2.011GluLys: 2.011 ± 0.048	7.645GluLeu: 7.645 ± 0.095	1.866GluMet: 1.866 ± 0.037	2.625GluAsn: 2.625 ± 0.053	3.925GluPro: 3.925 ± 0.064	2.503GluGln: 2.503 ± 0.052	8.604GluArg: 8.604 ± 0.118	5.177GluSer: 5.177 ± 0.069	6.532GluThr: 6.532 ± 0.09	5.733GluVal: 5.733 ± 0.097	1.266GluTrp: 1.266 ± 0.035	3.096GluTyr: 3.096 ± 0.061	0.001GluXaa: 0.001 ± 0.001
Phe	3.68PheAla: 3.68 ± 0.076	0.301PheCys: 0.301 ± 0.017	2.999PheAsp: 2.999 ± 0.055	3.523PheGlu: 3.523 ± 0.061	1.126PhePhe: 1.126 ± 0.035	3.489PheGly: 3.489 ± 0.065	0.636PheHis: 0.636 ± 0.026	1.203PheIle: 1.203 ± 0.041	0.531PheLys: 0.531 ± 0.023	3.024PheLeu: 3.024 ± 0.059	0.576PheMet: 0.576 ± 0.026	0.696PheAsn: 0.696 ± 0.027	1.457PhePro: 1.457 ± 0.037	0.694PheGln: 0.694 ± 0.025	1.788PheArg: 1.788 ± 0.039	1.995PheSer: 1.995 ± 0.044	1.777PheThr: 1.777 ± 0.046	3.325PheVal: 3.325 ± 0.063	0.419PheTrp: 0.419 ± 0.022	0.957PheTyr: 0.957 ± 0.033	0.0PheXaa: 0.0 ± 0.0
Gly	8.501GlyAla: 8.501 ± 0.115	0.762GlyCys: 0.762 ± 0.027	5.537GlyAsp: 5.537 ± 0.086	8.132GlyGlu: 8.132 ± 0.101	3.425GlyPhe: 3.425 ± 0.054	7.486GlyGly: 7.486 ± 0.121	1.702GlyHis: 1.702 ± 0.045	5.05GlyIle: 5.05 ± 0.074	1.974GlyLys: 1.974 ± 0.047	8.063GlyLeu: 8.063 ± 0.121	1.935GlyMet: 1.935 ± 0.046	1.951GlyAsn: 1.951 ± 0.049	3.483GlyPro: 3.483 ± 0.06	1.998GlyGln: 1.998 ± 0.052	5.246GlyArg: 5.246 ± 0.085	5.223GlySer: 5.223 ± 0.069	5.917GlyThr: 5.917 ± 0.078	7.37GlyVal: 7.37 ± 0.086	1.232GlyTrp: 1.232 ± 0.04	2.848GlyTyr: 2.848 ± 0.056	0.0GlyXaa: 0.0 ± 0.0
His	2.051HisAla: 2.051 ± 0.049	0.203HisCys: 0.203 ± 0.013	1.748HisAsp: 1.748 ± 0.046	1.848HisGlu: 1.848 ± 0.042	0.539HisPhe: 0.539 ± 0.024	1.989HisGly: 1.989 ± 0.05	0.564HisHis: 0.564 ± 0.03	0.795HisIle: 0.795 ± 0.026	0.286HisLys: 0.286 ± 0.021	1.774HisLeu: 1.774 ± 0.043	0.349HisMet: 0.349 ± 0.019	0.46HisAsn: 0.46 ± 0.025	1.28HisPro: 1.28 ± 0.034	0.467HisGln: 0.467 ± 0.021	1.328HisArg: 1.328 ± 0.036	0.915HisSer: 0.915 ± 0.033	1.205HisThr: 1.205 ± 0.038	1.683HisVal: 1.683 ± 0.045	0.248HisTrp: 0.248 ± 0.016	0.593HisTyr: 0.593 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	5.697IleAla: 5.697 ± 0.081	0.311IleCys: 0.311 ± 0.017	4.353IleAsp: 4.353 ± 0.07	5.585IleGlu: 5.585 ± 0.075	0.982IlePhe: 0.982 ± 0.036	4.594IleGly: 4.594 ± 0.068	0.991IleHis: 0.991 ± 0.031	1.492IleIle: 1.492 ± 0.046	0.791IleLys: 0.791 ± 0.027	3.105IleLeu: 3.105 ± 0.071	0.61IleMet: 0.61 ± 0.026	1.197IleAsn: 1.197 ± 0.034	2.34IlePro: 2.34 ± 0.049	1.129IleGln: 1.129 ± 0.037	2.775IleArg: 2.775 ± 0.05	2.35IleSer: 2.35 ± 0.053	2.93IleThr: 2.93 ± 0.055	4.074IleVal: 4.074 ± 0.077	0.372IleTrp: 0.372 ± 0.019	1.122IleTyr: 1.122 ± 0.037	0.0IleXaa: 0.0 ± 0.0
Lys	1.776LysAla: 1.776 ± 0.048	0.117LysCys: 0.117 ± 0.012	1.095LysAsp: 1.095 ± 0.046	1.502LysGlu: 1.502 ± 0.043	0.567LysPhe: 0.567 ± 0.025	1.446LysGly: 1.446 ± 0.036	0.503LysHis: 0.503 ± 0.023	0.787LysIle: 0.787 ± 0.033	0.615LysLys: 0.615 ± 0.04	1.581LysLeu: 1.581 ± 0.043	0.36LysMet: 0.36 ± 0.022	0.583LysAsn: 0.583 ± 0.027	0.952LysPro: 0.952 ± 0.029	0.737LysGln: 0.737 ± 0.028	1.858LysArg: 1.858 ± 0.048	1.104LysSer: 1.104 ± 0.032	1.269LysThr: 1.269 ± 0.034	1.128LysVal: 1.128 ± 0.035	0.231LysTrp: 0.231 ± 0.018	0.606LysTyr: 0.606 ± 0.024	0.0LysXaa: 0.0 ± 0.0
Leu	11.486LeuAla: 11.486 ± 0.149	0.668LeuCys: 0.668 ± 0.027	7.083LeuAsp: 7.083 ± 0.098	7.302LeuGlu: 7.302 ± 0.095	3.403LeuPhe: 3.403 ± 0.07	8.05LeuGly: 8.05 ± 0.108	1.468LeuHis: 1.468 ± 0.041	3.804LeuIle: 3.804 ± 0.067	1.52LeuLys: 1.52 ± 0.041	8.96LeuLeu: 8.96 ± 0.133	1.452LeuMet: 1.452 ± 0.038	1.858LeuAsn: 1.858 ± 0.044	4.328LeuPro: 4.328 ± 0.065	1.913LeuGln: 1.913 ± 0.047	5.302LeuArg: 5.302 ± 0.076	6.209LeuSer: 6.209 ± 0.086	5.36LeuThr: 5.36 ± 0.075	8.35LeuVal: 8.35 ± 0.122	0.896LeuTrp: 0.896 ± 0.031	2.357LeuTyr: 2.357 ± 0.056	0.0LeuXaa: 0.0 ± 0.0
Met	2.077MetAla: 2.077 ± 0.05	0.131MetCys: 0.131 ± 0.011	1.316MetAsp: 1.316 ± 0.04	1.252MetGlu: 1.252 ± 0.037	0.57MetPhe: 0.57 ± 0.022	1.703MetGly: 1.703 ± 0.04	0.391MetHis: 0.391 ± 0.019	0.851MetIle: 0.851 ± 0.034	0.51MetLys: 0.51 ± 0.025	1.655MetLeu: 1.655 ± 0.048	0.377MetMet: 0.377 ± 0.022	0.751MetAsn: 0.751 ± 0.026	0.818MetPro: 0.818 ± 0.027	0.458MetGln: 0.458 ± 0.02	1.102MetArg: 1.102 ± 0.033	1.568MetSer: 1.568 ± 0.037	1.412MetThr: 1.412 ± 0.035	1.41MetVal: 1.41 ± 0.038	0.184MetTrp: 0.184 ± 0.013	0.442MetTyr: 0.442 ± 0.022	0.0MetXaa: 0.0 ± 0.0
Asn	2.691AsnAla: 2.691 ± 0.053	0.242AsnCys: 0.242 ± 0.018	1.698AsnAsp: 1.698 ± 0.045	1.925AsnGlu: 1.925 ± 0.051	0.666AsnPhe: 0.666 ± 0.024	2.027AsnGly: 2.027 ± 0.046	0.556AsnHis: 0.556 ± 0.022	0.93AsnIle: 0.93 ± 0.03	0.421AsnLys: 0.421 ± 0.022	1.856AsnLeu: 1.856 ± 0.048	0.421AsnMet: 0.421 ± 0.02	0.575AsnAsn: 0.575 ± 0.029	1.548AsnPro: 1.548 ± 0.037	0.706AsnGln: 0.706 ± 0.027	1.721AsnArg: 1.721 ± 0.039	0.992AsnSer: 0.992 ± 0.039	1.417AsnThr: 1.417 ± 0.039	2.195AsnVal: 2.195 ± 0.047	0.316AsnTrp: 0.316 ± 0.017	0.705AsnTyr: 0.705 ± 0.025	0.0AsnXaa: 0.0 ± 0.0
Pro	4.74ProAla: 4.74 ± 0.086	0.252ProCys: 0.252 ± 0.016	4.445ProAsp: 4.445 ± 0.073	5.38ProGlu: 5.38 ± 0.082	1.606ProPhe: 1.606 ± 0.037	3.786ProGly: 3.786 ± 0.073	0.94ProHis: 0.94 ± 0.026	2.267ProIle: 2.267 ± 0.045	0.87ProLys: 0.87 ± 0.03	3.807ProLeu: 3.807 ± 0.059	0.886ProMet: 0.886 ± 0.028	1.146ProAsn: 1.146 ± 0.034	2.076ProPro: 2.076 ± 0.046	0.954ProGln: 0.954 ± 0.03	2.387ProArg: 2.387 ± 0.049	2.389ProSer: 2.389 ± 0.052	3.111ProThr: 3.111 ± 0.055	4.101ProVal: 4.101 ± 0.069	0.534ProTrp: 0.534 ± 0.025	1.233ProTyr: 1.233 ± 0.036	0.0ProXaa: 0.0 ± 0.0
Gln	2.242GlnAla: 2.242 ± 0.054	0.151GlnCys: 0.151 ± 0.013	1.219GlnAsp: 1.219 ± 0.036	1.666GlnGlu: 1.666 ± 0.043	1.01GlnPhe: 1.01 ± 0.032	1.656GlnGly: 1.656 ± 0.043	0.54GlnHis: 0.54 ± 0.025	1.149GlnIle: 1.149 ± 0.041	0.601GlnLys: 0.601 ± 0.026	2.294GlnLeu: 2.294 ± 0.057	0.555GlnMet: 0.555 ± 0.025	0.702GlnAsn: 0.702 ± 0.025	1.1GlnPro: 1.1 ± 0.037	0.957GlnGln: 0.957 ± 0.036	1.96GlnArg: 1.96 ± 0.046	1.482GlnSer: 1.482 ± 0.044	1.557GlnThr: 1.557 ± 0.041	1.61GlnVal: 1.61 ± 0.04	0.352GlnTrp: 0.352 ± 0.022	0.818GlnTyr: 0.818 ± 0.029	0.0GlnXaa: 0.0 ± 0.0
Arg	6.568ArgAla: 6.568 ± 0.096	0.487ArgCys: 0.487 ± 0.026	4.377ArgAsp: 4.377 ± 0.072	7.901ArgGlu: 7.901 ± 0.115	2.465ArgPhe: 2.465 ± 0.05	4.73ArgGly: 4.73 ± 0.079	1.266ArgHis: 1.266 ± 0.034	3.42ArgIle: 3.42 ± 0.055	1.471ArgLys: 1.471 ± 0.045	6.141ArgLeu: 6.141 ± 0.089	1.526ArgMet: 1.526 ± 0.036	1.588ArgAsn: 1.588 ± 0.042	2.673ArgPro: 2.673 ± 0.05	1.641ArgGln: 1.641 ± 0.046	4.769ArgArg: 4.769 ± 0.086	3.522ArgSer: 3.522 ± 0.069	4.182ArgThr: 4.182 ± 0.078	5.282ArgVal: 5.282 ± 0.082	0.802ArgTrp: 0.802 ± 0.029	2.07ArgTyr: 2.07 ± 0.048	0.0ArgXaa: 0.0 ± 0.0
Ser	5.403SerAla: 5.403 ± 0.075	0.342SerCys: 0.342 ± 0.02	4.014SerAsp: 4.014 ± 0.074	4.808SerGlu: 4.808 ± 0.065	1.847SerPhe: 1.847 ± 0.043	5.49SerGly: 5.49 ± 0.078	1.055SerHis: 1.055 ± 0.034	2.897SerIle: 2.897 ± 0.051	1.213SerLys: 1.213 ± 0.038	4.952SerLeu: 4.952 ± 0.08	1.246SerMet: 1.246 ± 0.036	1.35SerAsn: 1.35 ± 0.044	2.665SerPro: 2.665 ± 0.053	1.445SerGln: 1.445 ± 0.041	3.245SerArg: 3.245 ± 0.066	2.86SerSer: 2.86 ± 0.074	3.389SerThr: 3.389 ± 0.054	4.902SerVal: 4.902 ± 0.071	0.593SerTrp: 0.593 ± 0.023	1.459SerTyr: 1.459 ± 0.04	0.0SerXaa: 0.0 ± 0.0
Thr	6.335ThrAla: 6.335 ± 0.089	0.417ThrCys: 0.417 ± 0.02	5.186ThrAsp: 5.186 ± 0.081	4.911ThrGlu: 4.911 ± 0.066	2.038ThrPhe: 2.038 ± 0.046	5.799ThrGly: 5.799 ± 0.077	1.275ThrHis: 1.275 ± 0.035	3.133ThrIle: 3.133 ± 0.067	1.076ThrLys: 1.076 ± 0.034	5.808ThrLeu: 5.808 ± 0.079	1.132ThrMet: 1.132 ± 0.036	1.479ThrAsn: 1.479 ± 0.035	3.268ThrPro: 3.268 ± 0.054	1.413ThrGln: 1.413 ± 0.04	3.395ThrArg: 3.395 ± 0.051	2.781ThrSer: 2.781 ± 0.056	4.108ThrThr: 4.108 ± 0.066	6.485ThrVal: 6.485 ± 0.079	0.603ThrTrp: 0.603 ± 0.023	1.671ThrTyr: 1.671 ± 0.043	0.001ThrXaa: 0.001 ± 0.001
Val	8.963ValAla: 8.963 ± 0.106	0.739ValCys: 0.739 ± 0.028	5.636ValAsp: 5.636 ± 0.079	8.02ValGlu: 8.02 ± 0.085	3.152ValPhe: 3.152 ± 0.065	7.747ValGly: 7.747 ± 0.109	1.696ValHis: 1.696 ± 0.044	3.898ValIle: 3.898 ± 0.061	1.326ValLys: 1.326 ± 0.033	8.58ValLeu: 8.58 ± 0.121	1.451ValMet: 1.451 ± 0.033	1.805ValAsn: 1.805 ± 0.042	4.229ValPro: 4.229 ± 0.072	1.663ValGln: 1.663 ± 0.044	5.284ValArg: 5.284 ± 0.072	4.982ValSer: 4.982 ± 0.066	5.092ValThr: 5.092 ± 0.08	7.765ValVal: 7.765 ± 0.124	0.825ValTrp: 0.825 ± 0.031	2.113ValTyr: 2.113 ± 0.049	0.0ValXaa: 0.0 ± 0.0
Trp	0.914TrpAla: 0.914 ± 0.028	0.091TrpCys: 0.091 ± 0.009	0.798TrpAsp: 0.798 ± 0.035	0.924TrpGlu: 0.924 ± 0.036	0.511TrpPhe: 0.511 ± 0.023	0.84TrpGly: 0.84 ± 0.033	0.25TrpHis: 0.25 ± 0.014	0.635TrpIle: 0.635 ± 0.024	0.285TrpLys: 0.285 ± 0.016	1.226TrpLeu: 1.226 ± 0.039	0.252TrpMet: 0.252 ± 0.018	0.334TrpAsn: 0.334 ± 0.02	0.451TrpPro: 0.451 ± 0.023	0.328TrpGln: 0.328 ± 0.019	0.838TrpArg: 0.838 ± 0.026	0.628TrpSer: 0.628 ± 0.025	0.776TrpThr: 0.776 ± 0.029	0.845TrpVal: 0.845 ± 0.029	0.2TrpTrp: 0.2 ± 0.016	0.393TrpTyr: 0.393 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.805TyrAla: 2.805 ± 0.055	0.266TyrCys: 0.266 ± 0.016	2.514TyrAsp: 2.514 ± 0.052	2.594TyrGlu: 2.594 ± 0.056	0.893TyrPhe: 0.893 ± 0.029	2.571TyrGly: 2.571 ± 0.049	0.689TyrHis: 0.689 ± 0.027	0.852TyrIle: 0.852 ± 0.032	0.439TyrLys: 0.439 ± 0.022	2.6TyrLeu: 2.6 ± 0.05	0.426TyrMet: 0.426 ± 0.019	0.704TyrAsn: 0.704 ± 0.027	1.331TyrPro: 1.331 ± 0.038	0.727TyrGln: 0.727 ± 0.028	2.135TyrArg: 2.135 ± 0.05	1.369TyrSer: 1.369 ± 0.036	1.639TyrThr: 1.639 ± 0.042	2.296TyrVal: 2.296 ± 0.051	0.345TyrTrp: 0.345 ± 0.019	0.906TyrTyr: 0.906 ± 0.029	0.001TyrXaa: 0.001 ± 0.001
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.001XaaAsp: 0.001 ± 0.001	0.001XaaGlu: 0.001 ± 0.001	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.001XaaVal: 0.001 ± 0.001	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.005XaaXaa: 0.005 ± 0.006

Statistics based on 3779 proteins (1011784 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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