Amino acid dipepetide frequency for Fomitopsis rosea

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.243AlaAla: 10.243 ± 0.062	1.138AlaCys: 1.138 ± 0.016	5.051AlaAsp: 5.051 ± 0.033	5.686AlaGlu: 5.686 ± 0.044	3.324AlaPhe: 3.324 ± 0.028	5.925AlaGly: 5.925 ± 0.043	2.349AlaHis: 2.349 ± 0.023	4.098AlaIle: 4.098 ± 0.03	4.029AlaLys: 4.029 ± 0.038	8.953AlaLeu: 8.953 ± 0.049	2.157AlaMet: 2.157 ± 0.019	2.85AlaAsn: 2.85 ± 0.025	5.839AlaPro: 5.839 ± 0.047	3.809AlaGln: 3.809 ± 0.029	6.293AlaArg: 6.293 ± 0.044	8.061AlaSer: 8.061 ± 0.047	5.624AlaThr: 5.624 ± 0.034	6.023AlaVal: 6.023 ± 0.036	1.252AlaTrp: 1.252 ± 0.016	2.467AlaTyr: 2.467 ± 0.024	0.027AlaXaa: 0.027 ± 0.003
Cys	1.068CysAla: 1.068 ± 0.017	0.213CysCys: 0.213 ± 0.006	0.659CysAsp: 0.659 ± 0.012	0.586CysGlu: 0.586 ± 0.011	0.443CysPhe: 0.443 ± 0.01	0.869CysGly: 0.869 ± 0.014	0.322CysHis: 0.322 ± 0.008	0.616CysIle: 0.616 ± 0.011	0.509CysLys: 0.509 ± 0.01	1.143CysLeu: 1.143 ± 0.016	0.306CysMet: 0.306 ± 0.008	0.367CysAsn: 0.367 ± 0.009	0.722CysPro: 0.722 ± 0.012	0.405CysGln: 0.405 ± 0.01	0.743CysArg: 0.743 ± 0.013	0.846CysSer: 0.846 ± 0.012	0.714CysThr: 0.714 ± 0.012	0.814CysVal: 0.814 ± 0.013	0.186CysTrp: 0.186 ± 0.006	0.332CysTyr: 0.332 ± 0.009	0.004CysXaa: 0.004 ± 0.001
Asp	5.867AspAla: 5.867 ± 0.041	0.598AspCys: 0.598 ± 0.01	4.671AspAsp: 4.671 ± 0.041	4.933AspGlu: 4.933 ± 0.041	2.096AspPhe: 2.096 ± 0.02	4.182AspGly: 4.182 ± 0.033	1.306AspHis: 1.306 ± 0.016	2.914AspIle: 2.914 ± 0.023	2.171AspLys: 2.171 ± 0.024	5.047AspLeu: 5.047 ± 0.037	1.357AspMet: 1.357 ± 0.015	1.669AspAsn: 1.669 ± 0.019	3.594AspPro: 3.594 ± 0.029	1.644AspGln: 1.644 ± 0.017	3.07AspArg: 3.07 ± 0.028	3.957AspSer: 3.957 ± 0.03	3.097AspThr: 3.097 ± 0.024	4.552AspVal: 4.552 ± 0.029	0.943AspTrp: 0.943 ± 0.014	1.58AspTyr: 1.58 ± 0.019	0.021AspXaa: 0.021 ± 0.003
Glu	5.666GluAla: 5.666 ± 0.045	0.63GluCys: 0.63 ± 0.012	4.593GluAsp: 4.593 ± 0.035	5.607GluGlu: 5.607 ± 0.052	1.818GluPhe: 1.818 ± 0.02	3.885GluGly: 3.885 ± 0.032	1.635GluHis: 1.635 ± 0.018	2.595GluIle: 2.595 ± 0.024	2.995GluLys: 2.995 ± 0.029	5.648GluLeu: 5.648 ± 0.042	1.388GluMet: 1.388 ± 0.016	1.769GluAsn: 1.769 ± 0.018	3.091GluPro: 3.091 ± 0.026	2.498GluGln: 2.498 ± 0.023	4.427GluArg: 4.427 ± 0.037	3.907GluSer: 3.907 ± 0.031	3.163GluThr: 3.163 ± 0.026	3.879GluVal: 3.879 ± 0.029	0.947GluTrp: 0.947 ± 0.013	1.646GluTyr: 1.646 ± 0.018	0.017GluXaa: 0.017 ± 0.003
Phe	3.233PheAla: 3.233 ± 0.026	0.489PheCys: 0.489 ± 0.01	2.241PheAsp: 2.241 ± 0.02	1.97PheGlu: 1.97 ± 0.02	1.35PhePhe: 1.35 ± 0.021	2.496PheGly: 2.496 ± 0.024	0.837PheHis: 0.837 ± 0.011	1.615PheIle: 1.615 ± 0.019	1.348PheLys: 1.348 ± 0.018	3.211PheLeu: 3.211 ± 0.029	0.775PheMet: 0.775 ± 0.013	1.227PheAsn: 1.227 ± 0.017	1.907PhePro: 1.907 ± 0.021	1.086PheGln: 1.086 ± 0.015	1.932PheArg: 1.932 ± 0.02	2.687PheSer: 2.687 ± 0.023	2.036PheThr: 2.036 ± 0.022	2.517PheVal: 2.517 ± 0.024	0.564PheTrp: 0.564 ± 0.011	1.008PheTyr: 1.008 ± 0.015	0.009PheXaa: 0.009 ± 0.002
Gly	5.505GlyAla: 5.505 ± 0.041	0.811GlyCys: 0.811 ± 0.014	3.605GlyAsp: 3.605 ± 0.029	3.686GlyGlu: 3.686 ± 0.03	2.386GlyPhe: 2.386 ± 0.025	5.277GlyGly: 5.277 ± 0.049	1.75GlyHis: 1.75 ± 0.022	3.011GlyIle: 3.011 ± 0.026	3.26GlyLys: 3.26 ± 0.031	5.593GlyLeu: 5.593 ± 0.033	1.588GlyMet: 1.588 ± 0.022	2.046GlyAsn: 2.046 ± 0.022	3.531GlyPro: 3.531 ± 0.025	2.361GlyGln: 2.361 ± 0.025	4.287GlyArg: 4.287 ± 0.035	5.305GlySer: 5.305 ± 0.043	3.973GlyThr: 3.973 ± 0.034	4.288GlyVal: 4.288 ± 0.036	1.099GlyTrp: 1.099 ± 0.014	1.872GlyTyr: 1.872 ± 0.024	0.02GlyXaa: 0.02 ± 0.003
His	2.471HisAla: 2.471 ± 0.021	0.336HisCys: 0.336 ± 0.01	1.404HisAsp: 1.404 ± 0.02	1.36HisGlu: 1.36 ± 0.018	0.926HisPhe: 0.926 ± 0.014	1.741HisGly: 1.741 ± 0.023	0.799HisHis: 0.799 ± 0.015	1.249HisIle: 1.249 ± 0.017	0.924HisLys: 0.924 ± 0.014	2.457HisLeu: 2.457 ± 0.027	0.506HisMet: 0.506 ± 0.01	0.783HisAsn: 0.783 ± 0.012	1.865HisPro: 1.865 ± 0.023	0.825HisGln: 0.825 ± 0.015	1.684HisArg: 1.684 ± 0.018	1.854HisSer: 1.854 ± 0.022	1.448HisThr: 1.448 ± 0.019	1.741HisVal: 1.741 ± 0.017	0.387HisTrp: 0.387 ± 0.009	0.708HisTyr: 0.708 ± 0.012	0.007HisXaa: 0.007 ± 0.002
Ile	4.206IleAla: 4.206 ± 0.037	0.67IleCys: 0.67 ± 0.013	2.71IleAsp: 2.71 ± 0.023	2.525IleGlu: 2.525 ± 0.022	1.614IlePhe: 1.614 ± 0.019	2.778IleGly: 2.778 ± 0.027	1.127IleHis: 1.127 ± 0.015	2.149IleIle: 2.149 ± 0.025	1.765IleLys: 1.765 ± 0.019	4.12IleLeu: 4.12 ± 0.032	0.928IleMet: 0.928 ± 0.016	1.409IleAsn: 1.409 ± 0.019	2.976IlePro: 2.976 ± 0.026	1.574IleGln: 1.574 ± 0.019	2.764IleArg: 2.764 ± 0.025	3.15IleSer: 3.15 ± 0.028	2.493IleThr: 2.493 ± 0.024	3.21IleVal: 3.21 ± 0.026	0.657IleTrp: 0.657 ± 0.014	1.226IleTyr: 1.226 ± 0.017	0.012IleXaa: 0.012 ± 0.002
Lys	4.304LysAla: 4.304 ± 0.038	0.437LysCys: 0.437 ± 0.01	2.484LysAsp: 2.484 ± 0.029	2.974LysGlu: 2.974 ± 0.03	1.188LysPhe: 1.188 ± 0.018	2.786LysGly: 2.786 ± 0.028	1.113LysHis: 1.113 ± 0.016	1.753LysIle: 1.753 ± 0.021	2.81LysLys: 2.81 ± 0.04	3.728LysLeu: 3.728 ± 0.031	0.867LysMet: 0.867 ± 0.013	1.25LysAsn: 1.25 ± 0.016	2.552LysPro: 2.552 ± 0.031	1.66LysGln: 1.66 ± 0.019	3.445LysArg: 3.445 ± 0.029	2.84LysSer: 2.84 ± 0.026	2.451LysThr: 2.451 ± 0.026	2.623LysVal: 2.623 ± 0.027	0.629LysTrp: 0.629 ± 0.012	1.202LysTyr: 1.202 ± 0.015	0.013LysXaa: 0.013 ± 0.002
Leu	8.694LeuAla: 8.694 ± 0.047	1.263LeuCys: 1.263 ± 0.019	5.349LeuAsp: 5.349 ± 0.031	5.436LeuGlu: 5.436 ± 0.04	3.171LeuPhe: 3.171 ± 0.027	5.522LeuGly: 5.522 ± 0.036	2.481LeuHis: 2.481 ± 0.025	3.532LeuIle: 3.532 ± 0.029	3.828LeuLys: 3.828 ± 0.034	8.416LeuLeu: 8.416 ± 0.055	1.741LeuMet: 1.741 ± 0.019	2.891LeuAsn: 2.891 ± 0.023	6.095LeuPro: 6.095 ± 0.037	3.691LeuGln: 3.691 ± 0.031	6.59LeuArg: 6.59 ± 0.045	7.317LeuSer: 7.317 ± 0.04	5.209LeuThr: 5.209 ± 0.038	5.86LeuVal: 5.86 ± 0.035	1.192LeuTrp: 1.192 ± 0.014	2.46LeuTyr: 2.46 ± 0.025	0.025LeuXaa: 0.025 ± 0.003
Met	1.943MetAla: 1.943 ± 0.02	0.245MetCys: 0.245 ± 0.007	1.295MetAsp: 1.295 ± 0.015	1.222MetGlu: 1.222 ± 0.015	0.746MetPhe: 0.746 ± 0.013	1.323MetGly: 1.323 ± 0.019	0.576MetHis: 0.576 ± 0.012	0.884MetIle: 0.884 ± 0.013	0.922MetLys: 0.922 ± 0.013	2.0MetLeu: 2.0 ± 0.021	0.509MetMet: 0.509 ± 0.01	0.714MetAsn: 0.714 ± 0.014	1.387MetPro: 1.387 ± 0.018	0.949MetGln: 0.949 ± 0.016	1.432MetArg: 1.432 ± 0.016	1.973MetSer: 1.973 ± 0.02	1.266MetThr: 1.266 ± 0.016	1.238MetVal: 1.238 ± 0.017	0.29MetTrp: 0.29 ± 0.007	0.581MetTyr: 0.581 ± 0.011	0.005MetXaa: 0.005 ± 0.001
Asn	3.21AsnAla: 3.21 ± 0.026	0.348AsnCys: 0.348 ± 0.009	1.669AsnAsp: 1.669 ± 0.019	1.668AsnGlu: 1.668 ± 0.017	1.084AsnPhe: 1.084 ± 0.014	2.476AsnGly: 2.476 ± 0.026	0.704AsnHis: 0.704 ± 0.013	1.666AsnIle: 1.666 ± 0.019	1.201AsnLys: 1.201 ± 0.017	2.755AsnLeu: 2.755 ± 0.025	0.719AsnMet: 0.719 ± 0.011	1.072AsnAsn: 1.072 ± 0.018	2.082AsnPro: 2.082 ± 0.023	0.965AsnGln: 0.965 ± 0.013	1.638AsnArg: 1.638 ± 0.018	2.09AsnSer: 2.09 ± 0.025	1.881AsnThr: 1.881 ± 0.022	2.399AsnVal: 2.399 ± 0.022	0.478AsnTrp: 0.478 ± 0.01	0.87AsnTyr: 0.87 ± 0.012	0.009AsnXaa: 0.009 ± 0.002
Pro	6.365ProAla: 6.365 ± 0.051	0.509ProCys: 0.509 ± 0.012	3.606ProAsp: 3.606 ± 0.027	4.062ProGlu: 4.062 ± 0.031	2.068ProPhe: 2.068 ± 0.022	4.015ProGly: 4.015 ± 0.032	1.596ProHis: 1.596 ± 0.019	2.462ProIle: 2.462 ± 0.024	2.34ProLys: 2.34 ± 0.027	5.197ProLeu: 5.197 ± 0.036	1.158ProMet: 1.158 ± 0.017	1.919ProAsn: 1.919 ± 0.023	6.321ProPro: 6.321 ± 0.073	2.398ProGln: 2.398 ± 0.028	3.903ProArg: 3.903 ± 0.035	6.754ProSer: 6.754 ± 0.055	4.352ProThr: 4.352 ± 0.035	4.096ProVal: 4.096 ± 0.032	0.737ProTrp: 0.737 ± 0.013	1.622ProTyr: 1.622 ± 0.021	0.023ProXaa: 0.023 ± 0.003
Gln	3.627GlnAla: 3.627 ± 0.027	0.441GlnCys: 0.441 ± 0.01	1.942GlnAsp: 1.942 ± 0.018	2.298GlnGlu: 2.298 ± 0.022	1.167GlnPhe: 1.167 ± 0.017	2.205GlnGly: 2.205 ± 0.02	1.049GlnHis: 1.049 ± 0.017	1.543GlnIle: 1.543 ± 0.02	1.569GlnLys: 1.569 ± 0.019	3.485GlnLeu: 3.485 ± 0.026	0.842GlnMet: 0.842 ± 0.014	1.181GlnAsn: 1.181 ± 0.017	2.493GlnPro: 2.493 ± 0.03	1.885GlnGln: 1.885 ± 0.036	2.672GlnArg: 2.672 ± 0.024	2.819GlnSer: 2.819 ± 0.028	2.2GlnThr: 2.2 ± 0.024	2.157GlnVal: 2.157 ± 0.021	0.576GlnTrp: 0.576 ± 0.011	1.124GlnTyr: 1.124 ± 0.013	0.011GlnXaa: 0.011 ± 0.002
Arg	6.076ArgAla: 6.076 ± 0.041	0.781ArgCys: 0.781 ± 0.012	3.616ArgAsp: 3.616 ± 0.026	4.168ArgGlu: 4.168 ± 0.032	2.138ArgPhe: 2.138 ± 0.022	3.906ArgGly: 3.906 ± 0.035	1.693ArgHis: 1.693 ± 0.018	2.881ArgIle: 2.881 ± 0.026	3.389ArgLys: 3.389 ± 0.03	6.028ArgLeu: 6.028 ± 0.038	1.48ArgMet: 1.48 ± 0.016	2.005ArgAsn: 2.005 ± 0.02	4.01ArgPro: 4.01 ± 0.032	2.461ArgGln: 2.461 ± 0.024	5.786ArgArg: 5.786 ± 0.043	4.896ArgSer: 4.896 ± 0.039	3.862ArgThr: 3.862 ± 0.029	4.018ArgVal: 4.018 ± 0.025	1.023ArgTrp: 1.023 ± 0.015	1.697ArgTyr: 1.697 ± 0.019	0.02ArgXaa: 0.02 ± 0.003
Ser	7.552SerAla: 7.552 ± 0.047	0.794SerCys: 0.794 ± 0.014	4.376SerAsp: 4.376 ± 0.037	4.034SerGlu: 4.034 ± 0.028	2.663SerPhe: 2.663 ± 0.026	5.319SerGly: 5.319 ± 0.043	1.86SerHis: 1.86 ± 0.02	3.35SerIle: 3.35 ± 0.03	3.13SerLys: 3.13 ± 0.03	7.095SerLeu: 7.095 ± 0.044	1.665SerMet: 1.665 ± 0.02	2.333SerAsn: 2.333 ± 0.024	5.904SerPro: 5.904 ± 0.053	2.94SerGln: 2.94 ± 0.028	4.965SerArg: 4.965 ± 0.037	8.601SerSer: 8.601 ± 0.083	5.497SerThr: 5.497 ± 0.042	5.014SerVal: 5.014 ± 0.037	1.015SerTrp: 1.015 ± 0.015	1.91SerTyr: 1.91 ± 0.019	0.024SerXaa: 0.024 ± 0.003
Thr	5.501ThrAla: 5.501 ± 0.042	0.708ThrCys: 0.708 ± 0.012	3.011ThrAsp: 3.011 ± 0.022	3.026ThrGlu: 3.026 ± 0.027	2.273ThrPhe: 2.273 ± 0.021	3.82ThrGly: 3.82 ± 0.036	1.447ThrHis: 1.447 ± 0.018	2.821ThrIle: 2.821 ± 0.026	2.277ThrLys: 2.277 ± 0.024	5.632ThrLeu: 5.632 ± 0.036	1.204ThrMet: 1.204 ± 0.014	1.819ThrAsn: 1.819 ± 0.021	4.596ThrPro: 4.596 ± 0.043	2.069ThrGln: 2.069 ± 0.023	3.475ThrArg: 3.475 ± 0.029	5.295ThrSer: 5.295 ± 0.04	3.958ThrThr: 3.958 ± 0.033	3.997ThrVal: 3.997 ± 0.033	0.798ThrTrp: 0.798 ± 0.013	1.63ThrTyr: 1.63 ± 0.021	0.016ThrXaa: 0.016 ± 0.002
Val	5.967ValAla: 5.967 ± 0.031	0.872ValCys: 0.872 ± 0.012	4.271ValAsp: 4.271 ± 0.031	4.09ValGlu: 4.09 ± 0.032	2.509ValPhe: 2.509 ± 0.023	3.94ValGly: 3.94 ± 0.029	1.722ValHis: 1.722 ± 0.02	2.927ValIle: 2.927 ± 0.027	2.858ValLys: 2.858 ± 0.029	6.338ValLeu: 6.338 ± 0.038	1.34ValMet: 1.34 ± 0.017	2.133ValAsn: 2.133 ± 0.021	4.352ValPro: 4.352 ± 0.032	2.553ValGln: 2.553 ± 0.024	4.118ValArg: 4.118 ± 0.033	4.726ValSer: 4.726 ± 0.035	3.626ValThr: 3.626 ± 0.028	4.815ValVal: 4.815 ± 0.037	0.976ValTrp: 0.976 ± 0.013	1.906ValTyr: 1.906 ± 0.021	0.018ValXaa: 0.018 ± 0.002
Trp	1.177TrpAla: 1.177 ± 0.015	0.198TrpCys: 0.198 ± 0.007	0.934TrpAsp: 0.934 ± 0.015	0.864TrpGlu: 0.864 ± 0.013	0.516TrpPhe: 0.516 ± 0.011	0.839TrpGly: 0.839 ± 0.014	0.397TrpHis: 0.397 ± 0.008	0.684TrpIle: 0.684 ± 0.012	0.731TrpLys: 0.731 ± 0.013	1.357TrpLeu: 1.357 ± 0.018	0.348TrpMet: 0.348 ± 0.007	0.55TrpAsn: 0.55 ± 0.01	0.657TrpPro: 0.657 ± 0.012	0.569TrpGln: 0.569 ± 0.01	1.071TrpArg: 1.071 ± 0.015	1.038TrpSer: 1.038 ± 0.015	0.924TrpThr: 0.924 ± 0.015	0.881TrpVal: 0.881 ± 0.014	0.291TrpTrp: 0.291 ± 0.008	0.439TrpTyr: 0.439 ± 0.008	0.002TrpXaa: 0.002 ± 0.001
Tyr	2.485TyrAla: 2.485 ± 0.024	0.383TyrCys: 0.383 ± 0.009	1.759TyrAsp: 1.759 ± 0.019	1.591TyrGlu: 1.591 ± 0.018	1.047TyrPhe: 1.047 ± 0.015	1.926TyrGly: 1.926 ± 0.025	0.702TyrHis: 0.702 ± 0.011	1.303TyrIle: 1.303 ± 0.018	1.041TyrLys: 1.041 ± 0.016	2.543TyrLeu: 2.543 ± 0.023	0.615TyrMet: 0.615 ± 0.012	0.986TyrAsn: 0.986 ± 0.015	1.508TyrPro: 1.508 ± 0.02	0.938TyrGln: 0.938 ± 0.012	1.625TyrArg: 1.625 ± 0.018	1.905TyrSer: 1.905 ± 0.022	1.584TyrThr: 1.584 ± 0.019	1.913TyrVal: 1.913 ± 0.023	0.424TyrTrp: 0.424 ± 0.01	0.897TyrTyr: 0.897 ± 0.015	0.006TyrXaa: 0.006 ± 0.001
Xaa	0.036XaaAla: 0.036 ± 0.004	0.003XaaCys: 0.003 ± 0.001	0.022XaaAsp: 0.022 ± 0.003	0.019XaaGlu: 0.019 ± 0.003	0.01XaaPhe: 0.01 ± 0.002	0.024XaaGly: 0.024 ± 0.003	0.009XaaHis: 0.009 ± 0.001	0.01XaaIle: 0.01 ± 0.002	0.011XaaLys: 0.011 ± 0.002	0.021XaaLeu: 0.021 ± 0.003	0.007XaaMet: 0.007 ± 0.001	0.008XaaAsn: 0.008 ± 0.001	0.019XaaPro: 0.019 ± 0.003	0.009XaaGln: 0.009 ± 0.001	0.019XaaArg: 0.019 ± 0.002	0.019XaaSer: 0.019 ± 0.003	0.013XaaThr: 0.013 ± 0.002	0.023XaaVal: 0.023 ± 0.003	0.003XaaTrp: 0.003 ± 0.001	0.004XaaTyr: 0.004 ± 0.001	0.05XaaXaa: 0.05 ± 0.011

Statistics based on 11196 proteins (5146711 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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