Amino acid dipepetide frequency for Arenimonas composti TR7-09 = DSM 18010

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	23.451AlaAla: 23.451 ± 0.287	1.25AlaCys: 1.25 ± 0.038	8.599AlaAsp: 8.599 ± 0.122	8.405AlaGlu: 8.405 ± 0.123	4.341AlaPhe: 4.341 ± 0.067	13.468AlaGly: 13.468 ± 0.149	2.587AlaHis: 2.587 ± 0.049	5.512AlaIle: 5.512 ± 0.08	3.003AlaLys: 3.003 ± 0.065	16.815AlaLeu: 16.815 ± 0.19	3.305AlaMet: 3.305 ± 0.055	2.598AlaAsn: 2.598 ± 0.056	7.441AlaPro: 7.441 ± 0.123	4.366AlaGln: 4.366 ± 0.08	11.389AlaArg: 11.389 ± 0.164	5.568AlaSer: 5.568 ± 0.088	6.694AlaThr: 6.694 ± 0.096	9.906AlaVal: 9.906 ± 0.127	2.445AlaTrp: 2.445 ± 0.061	2.342AlaTyr: 2.342 ± 0.055	0.0AlaXaa: 0.0 ± 0.0
Cys	1.107CysAla: 1.107 ± 0.034	0.116CysCys: 0.116 ± 0.012	0.453CysAsp: 0.453 ± 0.022	0.441CysGlu: 0.441 ± 0.022	0.253CysPhe: 0.253 ± 0.019	0.906CysGly: 0.906 ± 0.03	0.212CysHis: 0.212 ± 0.018	0.267CysIle: 0.267 ± 0.018	0.114CysLys: 0.114 ± 0.013	0.785CysLeu: 0.785 ± 0.031	0.124CysMet: 0.124 ± 0.011	0.187CysAsn: 0.187 ± 0.015	0.442CysPro: 0.442 ± 0.024	0.159CysGln: 0.159 ± 0.012	0.742CysArg: 0.742 ± 0.03	0.367CysSer: 0.367 ± 0.019	0.426CysThr: 0.426 ± 0.023	0.618CysVal: 0.618 ± 0.025	0.111CysTrp: 0.111 ± 0.011	0.201CysTyr: 0.201 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	8.986AspAla: 8.986 ± 0.128	0.451AspCys: 0.451 ± 0.021	3.843AspAsp: 3.843 ± 0.072	3.678AspGlu: 3.678 ± 0.069	2.284AspPhe: 2.284 ± 0.052	6.625AspGly: 6.625 ± 0.096	1.215AspHis: 1.215 ± 0.038	2.265AspIle: 2.265 ± 0.056	1.046AspLys: 1.046 ± 0.032	5.849AspLeu: 5.849 ± 0.089	0.97AspMet: 0.97 ± 0.035	1.063AspAsn: 1.063 ± 0.046	4.073AspPro: 4.073 ± 0.08	1.459AspGln: 1.459 ± 0.042	4.561AspArg: 4.561 ± 0.072	2.107AspSer: 2.107 ± 0.047	2.555AspThr: 2.555 ± 0.053	4.331AspVal: 4.331 ± 0.076	1.13AspTrp: 1.13 ± 0.039	1.587AspTyr: 1.587 ± 0.046	0.0AspXaa: 0.0 ± 0.0
Glu	8.237GluAla: 8.237 ± 0.115	0.362GluCys: 0.362 ± 0.021	2.675GluAsp: 2.675 ± 0.054	2.685GluGlu: 2.685 ± 0.063	1.989GluPhe: 1.989 ± 0.052	4.249GluGly: 4.249 ± 0.068	1.428GluHis: 1.428 ± 0.047	2.563GluIle: 2.563 ± 0.046	1.433GluLys: 1.433 ± 0.042	6.932GluLeu: 6.932 ± 0.101	1.165GluMet: 1.165 ± 0.037	1.187GluAsn: 1.187 ± 0.037	2.857GluPro: 2.857 ± 0.064	2.262GluGln: 2.262 ± 0.063	5.874GluArg: 5.874 ± 0.096	2.381GluSer: 2.381 ± 0.049	2.707GluThr: 2.707 ± 0.059	4.359GluVal: 4.359 ± 0.078	0.693GluTrp: 0.693 ± 0.028	1.052GluTyr: 1.052 ± 0.033	0.0GluXaa: 0.0 ± 0.0
Phe	5.317PheAla: 5.317 ± 0.081	0.342PheCys: 0.342 ± 0.018	2.543PheAsp: 2.543 ± 0.059	2.093PheGlu: 2.093 ± 0.047	1.169PhePhe: 1.169 ± 0.037	3.281PheGly: 3.281 ± 0.07	0.771PheHis: 0.771 ± 0.031	1.075PheIle: 1.075 ± 0.037	0.563PheLys: 0.563 ± 0.026	3.187PheLeu: 3.187 ± 0.062	0.551PheMet: 0.551 ± 0.024	0.841PheAsn: 0.841 ± 0.033	1.544PhePro: 1.544 ± 0.04	0.867PheGln: 0.867 ± 0.027	2.533PheArg: 2.533 ± 0.057	1.655PheSer: 1.655 ± 0.039	1.594PheThr: 1.594 ± 0.043	2.836PheVal: 2.836 ± 0.061	0.492PheTrp: 0.492 ± 0.022	0.655PheTyr: 0.655 ± 0.031	0.0PheXaa: 0.0 ± 0.0
Gly	10.004GlyAla: 10.004 ± 0.116	0.825GlyCys: 0.825 ± 0.03	5.864GlyAsp: 5.864 ± 0.095	5.864GlyGlu: 5.864 ± 0.087	3.572GlyPhe: 3.572 ± 0.061	8.012GlyGly: 8.012 ± 0.137	2.041GlyHis: 2.041 ± 0.046	3.898GlyIle: 3.898 ± 0.083	2.352GlyLys: 2.352 ± 0.064	9.239GlyLeu: 9.239 ± 0.096	2.17GlyMet: 2.17 ± 0.045	2.24GlyAsn: 2.24 ± 0.055	3.477GlyPro: 3.477 ± 0.064	2.693GlyGln: 2.693 ± 0.058	7.549GlyArg: 7.549 ± 0.105	4.446GlySer: 4.446 ± 0.075	4.008GlyThr: 4.008 ± 0.083	6.67GlyVal: 6.67 ± 0.088	1.773GlyTrp: 1.773 ± 0.058	2.141GlyTyr: 2.141 ± 0.053	0.0GlyXaa: 0.0 ± 0.0
His	3.027HisAla: 3.027 ± 0.062	0.245HisCys: 0.245 ± 0.015	1.371HisAsp: 1.371 ± 0.043	1.202HisGlu: 1.202 ± 0.034	0.811HisPhe: 0.811 ± 0.029	2.224HisGly: 2.224 ± 0.049	0.56HisHis: 0.56 ± 0.024	0.648HisIle: 0.648 ± 0.03	0.324HisLys: 0.324 ± 0.022	2.228HisLeu: 2.228 ± 0.049	0.304HisMet: 0.304 ± 0.02	0.353HisAsn: 0.353 ± 0.02	1.453HisPro: 1.453 ± 0.041	0.52HisGln: 0.52 ± 0.023	1.748HisArg: 1.748 ± 0.043	0.81HisSer: 0.81 ± 0.032	0.831HisThr: 0.831 ± 0.029	1.694HisVal: 1.694 ± 0.042	0.452HisTrp: 0.452 ± 0.022	0.554HisTyr: 0.554 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	6.642IleAla: 6.642 ± 0.086	0.322IleCys: 0.322 ± 0.016	3.108IleAsp: 3.108 ± 0.056	2.828IleGlu: 2.828 ± 0.057	0.992IlePhe: 0.992 ± 0.04	4.071IleGly: 4.071 ± 0.091	0.775IleHis: 0.775 ± 0.025	1.077IleIle: 1.077 ± 0.039	0.738IleLys: 0.738 ± 0.035	2.89IleLeu: 2.89 ± 0.064	0.427IleMet: 0.427 ± 0.022	0.915IleAsn: 0.915 ± 0.035	1.919IlePro: 1.919 ± 0.047	0.901IleGln: 0.901 ± 0.032	2.747IleArg: 2.747 ± 0.058	1.71IleSer: 1.71 ± 0.047	1.916IleThr: 1.916 ± 0.045	3.375IleVal: 3.375 ± 0.07	0.378IleTrp: 0.378 ± 0.018	0.703IleTyr: 0.703 ± 0.035	0.0IleXaa: 0.0 ± 0.0
Lys	2.906LysAla: 2.906 ± 0.065	0.114LysCys: 0.114 ± 0.01	1.065LysAsp: 1.065 ± 0.042	1.007LysGlu: 1.007 ± 0.042	0.612LysPhe: 0.612 ± 0.026	1.568LysGly: 1.568 ± 0.041	0.437LysHis: 0.437 ± 0.022	0.894LysIle: 0.894 ± 0.04	0.836LysLys: 0.836 ± 0.051	2.577LysLeu: 2.577 ± 0.061	0.457LysMet: 0.457 ± 0.022	0.475LysAsn: 0.475 ± 0.023	1.541LysPro: 1.541 ± 0.041	0.743LysGln: 0.743 ± 0.034	1.753LysArg: 1.753 ± 0.045	1.028LysSer: 1.028 ± 0.042	1.108LysThr: 1.108 ± 0.037	1.772LysVal: 1.772 ± 0.05	0.214LysTrp: 0.214 ± 0.016	0.497LysTyr: 0.497 ± 0.029	0.0LysXaa: 0.0 ± 0.0
Leu	17.937LeuAla: 17.937 ± 0.209	0.828LeuCys: 0.828 ± 0.029	6.598LeuAsp: 6.598 ± 0.104	5.837LeuGlu: 5.837 ± 0.096	3.459LeuPhe: 3.459 ± 0.067	8.797LeuGly: 8.797 ± 0.117	2.43LeuHis: 2.43 ± 0.052	3.475LeuIle: 3.475 ± 0.075	2.528LeuLys: 2.528 ± 0.06	12.671LeuLeu: 12.671 ± 0.201	2.084LeuMet: 2.084 ± 0.052	1.884LeuAsn: 1.884 ± 0.047	7.059LeuPro: 7.059 ± 0.104	3.97LeuGln: 3.97 ± 0.07	10.21LeuArg: 10.21 ± 0.142	5.027LeuSer: 5.027 ± 0.075	4.468LeuThr: 4.468 ± 0.071	8.894LeuVal: 8.894 ± 0.107	1.418LeuTrp: 1.418 ± 0.046	1.994LeuTyr: 1.994 ± 0.044	0.0LeuXaa: 0.0 ± 0.0
Met	2.56MetAla: 2.56 ± 0.055	0.13MetCys: 0.13 ± 0.012	0.977MetAsp: 0.977 ± 0.035	0.831MetGlu: 0.831 ± 0.029	0.615MetPhe: 0.615 ± 0.028	1.319MetGly: 1.319 ± 0.037	0.411MetHis: 0.411 ± 0.02	0.777MetIle: 0.777 ± 0.032	0.714MetLys: 0.714 ± 0.027	2.27MetLeu: 2.27 ± 0.051	0.365MetMet: 0.365 ± 0.02	0.67MetAsn: 0.67 ± 0.029	1.377MetPro: 1.377 ± 0.04	0.717MetGln: 0.717 ± 0.027	1.691MetArg: 1.691 ± 0.037	1.411MetSer: 1.411 ± 0.037	1.179MetThr: 1.179 ± 0.036	1.351MetVal: 1.351 ± 0.035	0.193MetTrp: 0.193 ± 0.017	0.331MetTyr: 0.331 ± 0.02	0.0MetXaa: 0.0 ± 0.0
Asn	2.853AsnAla: 2.853 ± 0.06	0.203AsnCys: 0.203 ± 0.017	1.152AsnAsp: 1.152 ± 0.036	0.972AsnGlu: 0.972 ± 0.034	0.757AsnPhe: 0.757 ± 0.03	1.968AsnGly: 1.968 ± 0.063	0.433AsnHis: 0.433 ± 0.022	0.874AsnIle: 0.874 ± 0.029	0.402AsnLys: 0.402 ± 0.024	2.31AsnLeu: 2.31 ± 0.05	0.316AsnMet: 0.316 ± 0.018	0.474AsnAsn: 0.474 ± 0.026	1.599AsnPro: 1.599 ± 0.046	0.628AsnGln: 0.628 ± 0.037	1.73AsnArg: 1.73 ± 0.045	0.86AsnSer: 0.86 ± 0.051	1.046AsnThr: 1.046 ± 0.037	1.572AsnVal: 1.572 ± 0.045	0.318AsnTrp: 0.318 ± 0.019	0.493AsnTyr: 0.493 ± 0.024	0.0AsnXaa: 0.0 ± 0.0
Pro	8.736ProAla: 8.736 ± 0.136	0.302ProCys: 0.302 ± 0.017	3.807ProAsp: 3.807 ± 0.067	3.766ProGlu: 3.766 ± 0.068	1.666ProPhe: 1.666 ± 0.045	5.664ProGly: 5.664 ± 0.079	1.031ProHis: 1.031 ± 0.032	1.637ProIle: 1.637 ± 0.043	1.2ProLys: 1.2 ± 0.04	5.814ProLeu: 5.814 ± 0.085	1.195ProMet: 1.195 ± 0.033	1.002ProAsn: 1.002 ± 0.036	3.832ProPro: 3.832 ± 0.093	1.771ProGln: 1.771 ± 0.045	3.985ProArg: 3.985 ± 0.092	2.381ProSer: 2.381 ± 0.052	2.351ProThr: 2.351 ± 0.055	4.86ProVal: 4.86 ± 0.069	0.889ProTrp: 0.889 ± 0.031	0.975ProTyr: 0.975 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	4.803GlnAla: 4.803 ± 0.081	0.22GlnCys: 0.22 ± 0.017	1.265GlnAsp: 1.265 ± 0.04	1.347GlnGlu: 1.347 ± 0.039	0.891GlnPhe: 0.891 ± 0.034	2.181GlnGly: 2.181 ± 0.052	0.682GlnHis: 0.682 ± 0.029	1.214GlnIle: 1.214 ± 0.035	0.758GlnLys: 0.758 ± 0.031	3.702GlnLeu: 3.702 ± 0.07	0.612GlnMet: 0.612 ± 0.025	0.62GlnAsn: 0.62 ± 0.03	1.884GlnPro: 1.884 ± 0.052	1.369GlnGln: 1.369 ± 0.049	3.31GlnArg: 3.31 ± 0.066	1.248GlnSer: 1.248 ± 0.036	1.226GlnThr: 1.226 ± 0.037	2.652GlnVal: 2.652 ± 0.055	0.495GlnTrp: 0.495 ± 0.026	0.583GlnTyr: 0.583 ± 0.023	0.0GlnXaa: 0.0 ± 0.0
Arg	10.184ArgAla: 10.184 ± 0.126	0.655ArgCys: 0.655 ± 0.027	5.205ArgAsp: 5.205 ± 0.074	5.565ArgGlu: 5.565 ± 0.094	3.164ArgPhe: 3.164 ± 0.07	6.361ArgGly: 6.361 ± 0.082	2.168ArgHis: 2.168 ± 0.053	4.144ArgIle: 4.144 ± 0.069	1.645ArgLys: 1.645 ± 0.053	10.083ArgLeu: 10.083 ± 0.14	1.988ArgMet: 1.988 ± 0.049	1.797ArgAsn: 1.797 ± 0.048	4.246ArgPro: 4.246 ± 0.082	2.803ArgGln: 2.803 ± 0.063	8.104ArgArg: 8.104 ± 0.122	3.549ArgSer: 3.549 ± 0.063	3.364ArgThr: 3.364 ± 0.056	5.817ArgVal: 5.817 ± 0.083	1.673ArgTrp: 1.673 ± 0.048	2.031ArgTyr: 2.031 ± 0.051	0.0ArgXaa: 0.0 ± 0.0
Ser	5.567SerAla: 5.567 ± 0.08	0.343SerCys: 0.343 ± 0.021	2.327SerAsp: 2.327 ± 0.048	2.369SerGlu: 2.369 ± 0.056	1.653SerPhe: 1.653 ± 0.045	4.716SerGly: 4.716 ± 0.094	0.89SerHis: 0.89 ± 0.025	1.584SerIle: 1.584 ± 0.046	0.882SerLys: 0.882 ± 0.033	4.919SerLeu: 4.919 ± 0.076	0.855SerMet: 0.855 ± 0.03	1.041SerAsn: 1.041 ± 0.034	2.713SerPro: 2.713 ± 0.055	1.217SerGln: 1.217 ± 0.034	3.678SerArg: 3.678 ± 0.062	1.994SerSer: 1.994 ± 0.053	2.245SerThr: 2.245 ± 0.055	3.104SerVal: 3.104 ± 0.069	0.727SerTrp: 0.727 ± 0.031	0.977SerTyr: 0.977 ± 0.036	0.0SerXaa: 0.0 ± 0.0
Thr	6.064ThrAla: 6.064 ± 0.082	0.361ThrCys: 0.361 ± 0.018	2.286ThrAsp: 2.286 ± 0.049	1.896ThrGlu: 1.896 ± 0.045	1.421ThrPhe: 1.421 ± 0.034	4.721ThrGly: 4.721 ± 0.084	0.848ThrHis: 0.848 ± 0.038	1.939ThrIle: 1.939 ± 0.046	0.822ThrLys: 0.822 ± 0.029	5.582ThrLeu: 5.582 ± 0.081	0.891ThrMet: 0.891 ± 0.029	0.889ThrAsn: 0.889 ± 0.038	3.349ThrPro: 3.349 ± 0.066	1.067ThrGln: 1.067 ± 0.035	3.414ThrArg: 3.414 ± 0.06	2.001ThrSer: 2.001 ± 0.052	2.329ThrThr: 2.329 ± 0.059	4.013ThrVal: 4.013 ± 0.078	0.742ThrTrp: 0.742 ± 0.032	0.888ThrTyr: 0.888 ± 0.035	0.0ThrXaa: 0.0 ± 0.0
Val	10.903ValAla: 10.903 ± 0.12	0.637ValCys: 0.637 ± 0.029	4.994ValAsp: 4.994 ± 0.081	4.58ValGlu: 4.58 ± 0.078	2.79ValPhe: 2.79 ± 0.064	5.796ValGly: 5.796 ± 0.09	1.649ValHis: 1.649 ± 0.044	3.299ValIle: 3.299 ± 0.062	1.481ValLys: 1.481 ± 0.045	9.097ValLeu: 9.097 ± 0.107	1.476ValMet: 1.476 ± 0.045	1.774ValAsn: 1.774 ± 0.055	4.217ValPro: 4.217 ± 0.069	2.242ValGln: 2.242 ± 0.052	5.934ValArg: 5.934 ± 0.1	3.443ValSer: 3.443 ± 0.078	3.621ValThr: 3.621 ± 0.077	6.567ValVal: 6.567 ± 0.102	0.971ValTrp: 0.971 ± 0.03	1.398ValTyr: 1.398 ± 0.039	0.0ValXaa: 0.0 ± 0.0
Trp	1.401TrpAla: 1.401 ± 0.044	0.168TrpCys: 0.168 ± 0.014	0.679TrpAsp: 0.679 ± 0.025	0.622TrpGlu: 0.622 ± 0.025	0.681TrpPhe: 0.681 ± 0.027	0.93TrpGly: 0.93 ± 0.034	0.386TrpHis: 0.386 ± 0.019	0.742TrpIle: 0.742 ± 0.032	0.398TrpLys: 0.398 ± 0.023	2.468TrpLeu: 2.468 ± 0.062	0.33TrpMet: 0.33 ± 0.018	0.477TrpAsn: 0.477 ± 0.023	0.884TrpPro: 0.884 ± 0.033	0.698TrpGln: 0.698 ± 0.031	1.648TrpArg: 1.648 ± 0.054	0.853TrpSer: 0.853 ± 0.033	0.773TrpThr: 0.773 ± 0.027	0.958TrpVal: 0.958 ± 0.032	0.327TrpTrp: 0.327 ± 0.018	0.371TrpTyr: 0.371 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.802TyrAla: 2.802 ± 0.064	0.157TyrCys: 0.157 ± 0.012	1.267TyrAsp: 1.267 ± 0.041	1.099TyrGlu: 1.099 ± 0.032	0.79TyrPhe: 0.79 ± 0.028	1.985TyrGly: 1.985 ± 0.062	0.406TyrHis: 0.406 ± 0.022	0.552TyrIle: 0.552 ± 0.024	0.361TyrLys: 0.361 ± 0.018	2.146TyrLeu: 2.146 ± 0.052	0.302TyrMet: 0.302 ± 0.019	0.473TyrAsn: 0.473 ± 0.026	0.957TyrPro: 0.957 ± 0.034	0.61TyrGln: 0.61 ± 0.026	1.944TyrArg: 1.944 ± 0.047	0.963TyrSer: 0.963 ± 0.031	1.08TyrThr: 1.08 ± 0.038	1.521TyrVal: 1.521 ± 0.048	0.357TyrTrp: 0.357 ± 0.019	0.526TyrTyr: 0.526 ± 0.029	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2849 proteins (949738 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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