Amino acid dipepetide frequency for Gulosibacter sp. YIM 102482-1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	18.287AlaAla: 18.287 ± 0.253	0.638AlaCys: 0.638 ± 0.034	7.608AlaAsp: 7.608 ± 0.115	9.156AlaGlu: 9.156 ± 0.153	3.824AlaPhe: 3.824 ± 0.075	10.835AlaGly: 10.835 ± 0.127	2.403AlaHis: 2.403 ± 0.061	6.263AlaIle: 6.263 ± 0.106	3.218AlaLys: 3.218 ± 0.084	13.037AlaLeu: 13.037 ± 0.181	2.766AlaMet: 2.766 ± 0.064	3.044AlaAsn: 3.044 ± 0.073	6.17AlaPro: 6.17 ± 0.118	4.012AlaGln: 4.012 ± 0.081	8.445AlaArg: 8.445 ± 0.126	6.991AlaSer: 6.991 ± 0.103	7.612AlaThr: 7.612 ± 0.122	9.874AlaVal: 9.874 ± 0.14	1.707AlaTrp: 1.707 ± 0.052	2.259AlaTyr: 2.259 ± 0.051	0.0AlaXaa: 0.0 ± 0.0
Cys	0.7CysAla: 0.7 ± 0.034	0.055CysCys: 0.055 ± 0.008	0.331CysAsp: 0.331 ± 0.021	0.343CysGlu: 0.343 ± 0.02	0.173CysPhe: 0.173 ± 0.017	0.585CysGly: 0.585 ± 0.027	0.136CysHis: 0.136 ± 0.013	0.255CysIle: 0.255 ± 0.016	0.093CysLys: 0.093 ± 0.011	0.41CysLeu: 0.41 ± 0.023	0.083CysMet: 0.083 ± 0.01	0.139CysAsn: 0.139 ± 0.013	0.306CysPro: 0.306 ± 0.019	0.131CysGln: 0.131 ± 0.013	0.381CysArg: 0.381 ± 0.023	0.305CysSer: 0.305 ± 0.021	0.344CysThr: 0.344 ± 0.022	0.432CysVal: 0.432 ± 0.024	0.08CysTrp: 0.08 ± 0.009	0.13CysTyr: 0.13 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	9.117AspAla: 9.117 ± 0.125	0.255AspCys: 0.255 ± 0.018	4.258AspAsp: 4.258 ± 0.101	5.188AspGlu: 5.188 ± 0.095	1.898AspPhe: 1.898 ± 0.052	5.497AspGly: 5.497 ± 0.122	1.255AspHis: 1.255 ± 0.036	2.305AspIle: 2.305 ± 0.058	1.124AspLys: 1.124 ± 0.044	6.172AspLeu: 6.172 ± 0.109	0.835AspMet: 0.835 ± 0.032	1.17AspAsn: 1.17 ± 0.042	3.602AspPro: 3.602 ± 0.068	1.651AspGln: 1.651 ± 0.047	4.486AspArg: 4.486 ± 0.087	2.71AspSer: 2.71 ± 0.06	2.925AspThr: 2.925 ± 0.067	4.735AspVal: 4.735 ± 0.086	0.942AspTrp: 0.942 ± 0.035	1.464AspTyr: 1.464 ± 0.046	0.0AspXaa: 0.0 ± 0.0
Glu	7.776GluAla: 7.776 ± 0.126	0.299GluCys: 0.299 ± 0.018	2.731GluAsp: 2.731 ± 0.062	3.208GluGlu: 3.208 ± 0.077	2.487GluPhe: 2.487 ± 0.064	4.358GluGly: 4.358 ± 0.077	1.792GluHis: 1.792 ± 0.047	3.397GluIle: 3.397 ± 0.065	1.381GluLys: 1.381 ± 0.046	7.796GluLeu: 7.796 ± 0.12	1.187GluMet: 1.187 ± 0.039	1.316GluAsn: 1.316 ± 0.042	3.403GluPro: 3.403 ± 0.071	2.954GluGln: 2.954 ± 0.07	5.815GluArg: 5.815 ± 0.1	3.358GluSer: 3.358 ± 0.066	3.299GluThr: 3.299 ± 0.069	5.553GluVal: 5.553 ± 0.092	1.011GluTrp: 1.011 ± 0.032	1.322GluTyr: 1.322 ± 0.043	0.0GluXaa: 0.0 ± 0.0
Phe	4.421PheAla: 4.421 ± 0.078	0.192PheCys: 0.192 ± 0.016	2.597PheAsp: 2.597 ± 0.062	2.055PheGlu: 2.055 ± 0.057	1.076PhePhe: 1.076 ± 0.042	3.589PheGly: 3.589 ± 0.069	0.552PheHis: 0.552 ± 0.024	1.551PheIle: 1.551 ± 0.046	0.573PheLys: 0.573 ± 0.025	2.707PheLeu: 2.707 ± 0.062	0.538PheMet: 0.538 ± 0.027	0.864PheAsn: 0.864 ± 0.032	1.391PhePro: 1.391 ± 0.043	0.811PheGln: 0.811 ± 0.031	1.755PheArg: 1.755 ± 0.05	1.775PheSer: 1.775 ± 0.052	2.087PheThr: 2.087 ± 0.053	2.85PheVal: 2.85 ± 0.064	0.457PheTrp: 0.457 ± 0.025	0.644PheTyr: 0.644 ± 0.03	0.0PheXaa: 0.0 ± 0.0
Gly	9.987GlyAla: 9.987 ± 0.137	0.593GlyCys: 0.593 ± 0.032	4.999GlyAsp: 4.999 ± 0.091	5.522GlyGlu: 5.522 ± 0.076	3.208GlyPhe: 3.208 ± 0.069	7.237GlyGly: 7.237 ± 0.157	1.729GlyHis: 1.729 ± 0.049	4.552GlyIle: 4.552 ± 0.084	2.347GlyLys: 2.347 ± 0.066	8.021GlyLeu: 8.021 ± 0.115	2.168GlyMet: 2.168 ± 0.057	2.135GlyAsn: 2.135 ± 0.059	3.387GlyPro: 3.387 ± 0.063	2.693GlyGln: 2.693 ± 0.091	5.751GlyArg: 5.751 ± 0.095	4.773GlySer: 4.773 ± 0.084	5.303GlyThr: 5.303 ± 0.096	7.254GlyVal: 7.254 ± 0.101	1.576GlyTrp: 1.576 ± 0.055	2.088GlyTyr: 2.088 ± 0.058	0.0GlyXaa: 0.0 ± 0.0
His	2.18HisAla: 2.18 ± 0.056	0.138HisCys: 0.138 ± 0.014	1.404HisAsp: 1.404 ± 0.046	1.453HisGlu: 1.453 ± 0.041	0.638HisPhe: 0.638 ± 0.029	1.903HisGly: 1.903 ± 0.051	0.53HisHis: 0.53 ± 0.024	0.82HisIle: 0.82 ± 0.03	0.325HisLys: 0.325 ± 0.02	2.068HisLeu: 2.068 ± 0.058	0.351HisMet: 0.351 ± 0.022	0.423HisAsn: 0.423 ± 0.022	1.572HisPro: 1.572 ± 0.049	0.564HisGln: 0.564 ± 0.028	1.644HisArg: 1.644 ± 0.049	1.078HisSer: 1.078 ± 0.037	1.042HisThr: 1.042 ± 0.034	1.509HisVal: 1.509 ± 0.048	0.289HisTrp: 0.289 ± 0.018	0.477HisTyr: 0.477 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	7.437IleAla: 7.437 ± 0.114	0.319IleCys: 0.319 ± 0.021	3.94IleAsp: 3.94 ± 0.08	3.444IleGlu: 3.444 ± 0.067	1.312IlePhe: 1.312 ± 0.048	4.824IleGly: 4.824 ± 0.098	0.768IleHis: 0.768 ± 0.03	2.287IleIle: 2.287 ± 0.061	0.957IleLys: 0.957 ± 0.035	3.567IleLeu: 3.567 ± 0.082	0.777IleMet: 0.777 ± 0.032	1.212IleAsn: 1.212 ± 0.042	2.401IlePro: 2.401 ± 0.058	1.067IleGln: 1.067 ± 0.035	2.981IleArg: 2.981 ± 0.065	2.494IleSer: 2.494 ± 0.054	3.121IleThr: 3.121 ± 0.062	4.66IleVal: 4.66 ± 0.087	0.618IleTrp: 0.618 ± 0.03	0.914IleTyr: 0.914 ± 0.033	0.0IleXaa: 0.0 ± 0.0
Lys	2.405LysAla: 2.405 ± 0.069	0.095LysCys: 0.095 ± 0.011	1.043LysAsp: 1.043 ± 0.044	1.024LysGlu: 1.024 ± 0.045	0.779LysPhe: 0.779 ± 0.03	1.536LysGly: 1.536 ± 0.056	0.583LysHis: 0.583 ± 0.029	1.106LysIle: 1.106 ± 0.041	0.863LysLys: 0.863 ± 0.047	2.557LysLeu: 2.557 ± 0.063	0.516LysMet: 0.516 ± 0.031	0.597LysAsn: 0.597 ± 0.029	1.45LysPro: 1.45 ± 0.056	0.933LysGln: 0.933 ± 0.041	1.856LysArg: 1.856 ± 0.051	1.404LysSer: 1.404 ± 0.046	1.356LysThr: 1.356 ± 0.049	1.937LysVal: 1.937 ± 0.063	0.335LysTrp: 0.335 ± 0.02	0.544LysTyr: 0.544 ± 0.027	0.0LysXaa: 0.0 ± 0.0
Leu	14.049LeuAla: 14.049 ± 0.186	0.489LeuCys: 0.489 ± 0.024	6.862LeuAsp: 6.862 ± 0.114	6.217LeuGlu: 6.217 ± 0.099	2.799LeuPhe: 2.799 ± 0.069	8.981LeuGly: 8.981 ± 0.129	1.787LeuHis: 1.787 ± 0.046	4.945LeuIle: 4.945 ± 0.095	2.011LeuLys: 2.011 ± 0.057	9.581LeuLeu: 9.581 ± 0.151	1.643LeuMet: 1.643 ± 0.053	2.11LeuAsn: 2.11 ± 0.052	5.29LeuPro: 5.29 ± 0.092	2.616LeuGln: 2.616 ± 0.056	7.437LeuArg: 7.437 ± 0.12	5.109LeuSer: 5.109 ± 0.082	5.63LeuThr: 5.63 ± 0.095	8.817LeuVal: 8.817 ± 0.132	1.075LeuTrp: 1.075 ± 0.04	1.592LeuTyr: 1.592 ± 0.047	0.0LeuXaa: 0.0 ± 0.0
Met	2.068MetAla: 2.068 ± 0.055	0.133MetCys: 0.133 ± 0.013	0.776MetAsp: 0.776 ± 0.03	0.657MetGlu: 0.657 ± 0.029	0.647MetPhe: 0.647 ± 0.034	1.3MetGly: 1.3 ± 0.043	0.445MetHis: 0.445 ± 0.023	0.939MetIle: 0.939 ± 0.037	0.466MetLys: 0.466 ± 0.024	2.192MetLeu: 2.192 ± 0.052	0.399MetMet: 0.399 ± 0.029	0.592MetAsn: 0.592 ± 0.028	1.253MetPro: 1.253 ± 0.041	0.77MetGln: 0.77 ± 0.029	1.759MetArg: 1.759 ± 0.044	1.498MetSer: 1.498 ± 0.044	1.73MetThr: 1.73 ± 0.045	1.318MetVal: 1.318 ± 0.041	0.252MetTrp: 0.252 ± 0.017	0.299MetTyr: 0.299 ± 0.02	0.0MetXaa: 0.0 ± 0.0
Asn	2.846AsnAla: 2.846 ± 0.056	0.146AsnCys: 0.146 ± 0.013	1.528AsnAsp: 1.528 ± 0.048	1.576AsnGlu: 1.576 ± 0.043	0.773AsnPhe: 0.773 ± 0.034	2.135AsnGly: 2.135 ± 0.057	0.483AsnHis: 0.483 ± 0.025	1.044AsnIle: 1.044 ± 0.038	0.542AsnLys: 0.542 ± 0.031	2.236AsnLeu: 2.236 ± 0.053	0.461AsnMet: 0.461 ± 0.023	0.623AsnAsn: 0.623 ± 0.033	1.778AsnPro: 1.778 ± 0.053	0.758AsnGln: 0.758 ± 0.037	1.559AsnArg: 1.559 ± 0.043	1.283AsnSer: 1.283 ± 0.04	1.367AsnThr: 1.367 ± 0.052	1.878AsnVal: 1.878 ± 0.042	0.441AsnTrp: 0.441 ± 0.024	0.591AsnTyr: 0.591 ± 0.027	0.0AsnXaa: 0.0 ± 0.0
Pro	6.564ProAla: 6.564 ± 0.12	0.17ProCys: 0.17 ± 0.017	3.418ProAsp: 3.418 ± 0.062	4.249ProGlu: 4.249 ± 0.079	1.686ProPhe: 1.686 ± 0.042	4.776ProGly: 4.776 ± 0.1	1.089ProHis: 1.089 ± 0.036	2.492ProIle: 2.492 ± 0.053	1.409ProLys: 1.409 ± 0.044	4.58ProLeu: 4.58 ± 0.074	1.003ProMet: 1.003 ± 0.036	1.482ProAsn: 1.482 ± 0.053	2.182ProPro: 2.182 ± 0.072	1.707ProGln: 1.707 ± 0.055	3.046ProArg: 3.046 ± 0.068	2.963ProSer: 2.963 ± 0.065	3.428ProThr: 3.428 ± 0.079	4.541ProVal: 4.541 ± 0.081	0.749ProTrp: 0.749 ± 0.029	1.047ProTyr: 1.047 ± 0.04	0.0ProXaa: 0.0 ± 0.0
Gln	3.764GlnAla: 3.764 ± 0.067	0.156GlnCys: 0.156 ± 0.012	1.381GlnAsp: 1.381 ± 0.042	1.467GlnGlu: 1.467 ± 0.044	1.028GlnPhe: 1.028 ± 0.04	2.306GlnGly: 2.306 ± 0.064	0.811GlnHis: 0.811 ± 0.034	1.514GlnIle: 1.514 ± 0.04	0.604GlnLys: 0.604 ± 0.031	3.943GlnLeu: 3.943 ± 0.067	0.586GlnMet: 0.586 ± 0.028	0.658GlnAsn: 0.658 ± 0.03	1.92GlnPro: 1.92 ± 0.075	1.659GlnGln: 1.659 ± 0.069	2.727GlnArg: 2.727 ± 0.06	1.561GlnSer: 1.561 ± 0.052	1.534GlnThr: 1.534 ± 0.047	2.602GlnVal: 2.602 ± 0.052	0.507GlnTrp: 0.507 ± 0.025	0.626GlnTyr: 0.626 ± 0.033	0.0GlnXaa: 0.0 ± 0.0
Arg	8.445ArgAla: 8.445 ± 0.134	0.383ArgCys: 0.383 ± 0.022	4.468ArgAsp: 4.468 ± 0.08	5.205ArgGlu: 5.205 ± 0.099	2.374ArgPhe: 2.374 ± 0.056	5.235ArgGly: 5.235 ± 0.092	1.539ArgHis: 1.539 ± 0.046	4.105ArgIle: 4.105 ± 0.077	1.805ArgLys: 1.805 ± 0.052	6.997ArgLeu: 6.997 ± 0.12	1.735ArgMet: 1.735 ± 0.045	1.692ArgAsn: 1.692 ± 0.049	3.265ArgPro: 3.265 ± 0.068	2.225ArgGln: 2.225 ± 0.055	6.247ArgArg: 6.247 ± 0.113	3.762ArgSer: 3.762 ± 0.081	3.984ArgThr: 3.984 ± 0.078	5.516ArgVal: 5.516 ± 0.103	1.079ArgTrp: 1.079 ± 0.042	1.519ArgTyr: 1.519 ± 0.039	0.0ArgXaa: 0.0 ± 0.0
Ser	6.469SerAla: 6.469 ± 0.095	0.294SerCys: 0.294 ± 0.02	3.003SerAsp: 3.003 ± 0.057	3.105SerGlu: 3.105 ± 0.069	1.895SerPhe: 1.895 ± 0.045	5.345SerGly: 5.345 ± 0.086	0.98SerHis: 0.98 ± 0.031	2.675SerIle: 2.675 ± 0.063	1.393SerLys: 1.393 ± 0.05	5.065SerLeu: 5.065 ± 0.084	1.287SerMet: 1.287 ± 0.04	1.487SerAsn: 1.487 ± 0.043	2.933SerPro: 2.933 ± 0.068	1.595SerGln: 1.595 ± 0.044	3.478SerArg: 3.478 ± 0.08	3.267SerSer: 3.267 ± 0.076	3.471SerThr: 3.471 ± 0.073	4.237SerVal: 4.237 ± 0.071	0.911SerTrp: 0.911 ± 0.034	1.208SerTyr: 1.208 ± 0.038	0.0SerXaa: 0.0 ± 0.0
Thr	7.278ThrAla: 7.278 ± 0.112	0.325ThrCys: 0.325 ± 0.021	3.498ThrAsp: 3.498 ± 0.078	3.518ThrGlu: 3.518 ± 0.063	1.926ThrPhe: 1.926 ± 0.051	5.379ThrGly: 5.379 ± 0.089	1.192ThrHis: 1.192 ± 0.043	3.09ThrIle: 3.09 ± 0.066	1.429ThrLys: 1.429 ± 0.043	5.597ThrLeu: 5.597 ± 0.101	1.111ThrMet: 1.111 ± 0.044	1.564ThrAsn: 1.564 ± 0.054	3.89ThrPro: 3.89 ± 0.081	1.653ThrGln: 1.653 ± 0.044	3.564ThrArg: 3.564 ± 0.07	3.374ThrSer: 3.374 ± 0.062	3.945ThrThr: 3.945 ± 0.087	5.264ThrVal: 5.264 ± 0.107	0.832ThrTrp: 0.832 ± 0.029	1.219ThrTyr: 1.219 ± 0.04	0.0ThrXaa: 0.0 ± 0.0
Val	10.608ValAla: 10.608 ± 0.144	0.488ValCys: 0.488 ± 0.026	5.638ValAsp: 5.638 ± 0.083	5.063ValGlu: 5.063 ± 0.099	2.611ValPhe: 2.611 ± 0.06	6.472ValGly: 6.472 ± 0.097	1.638ValHis: 1.638 ± 0.052	4.46ValIle: 4.46 ± 0.08	1.736ValLys: 1.736 ± 0.057	8.556ValLeu: 8.556 ± 0.126	1.395ValMet: 1.395 ± 0.046	1.993ValAsn: 1.993 ± 0.05	4.634ValPro: 4.634 ± 0.076	2.153ValGln: 2.153 ± 0.06	5.778ValArg: 5.778 ± 0.104	4.437ValSer: 4.437 ± 0.075	5.626ValThr: 5.626 ± 0.097	7.77ValVal: 7.77 ± 0.126	1.067ValTrp: 1.067 ± 0.036	1.401ValTyr: 1.401 ± 0.042	0.0ValXaa: 0.0 ± 0.0
Trp	1.475TrpAla: 1.475 ± 0.044	0.095TrpCys: 0.095 ± 0.01	0.711TrpAsp: 0.711 ± 0.029	0.627TrpGlu: 0.627 ± 0.028	0.626TrpPhe: 0.626 ± 0.028	0.973TrpGly: 0.973 ± 0.038	0.36TrpHis: 0.36 ± 0.017	0.622TrpIle: 0.622 ± 0.025	0.288TrpLys: 0.288 ± 0.019	1.865TrpLeu: 1.865 ± 0.047	0.354TrpMet: 0.354 ± 0.019	0.445TrpAsn: 0.445 ± 0.026	0.747TrpPro: 0.747 ± 0.033	0.714TrpGln: 0.714 ± 0.031	1.319TrpArg: 1.319 ± 0.039	0.882TrpSer: 0.882 ± 0.032	0.723TrpThr: 0.723 ± 0.035	1.137TrpVal: 1.137 ± 0.037	0.426TrpTrp: 0.426 ± 0.026	0.291TrpTyr: 0.291 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.274TyrAla: 2.274 ± 0.056	0.145TyrCys: 0.145 ± 0.014	1.395TyrAsp: 1.395 ± 0.045	1.363TyrGlu: 1.363 ± 0.041	0.726TyrPhe: 0.726 ± 0.034	2.06TyrGly: 2.06 ± 0.054	0.335TyrHis: 0.335 ± 0.02	0.68TyrIle: 0.68 ± 0.032	0.357TyrLys: 0.357 ± 0.021	2.091TyrLeu: 2.091 ± 0.057	0.298TyrMet: 0.298 ± 0.021	0.499TyrAsn: 0.499 ± 0.027	1.01TyrPro: 1.01 ± 0.032	0.685TyrGln: 0.685 ± 0.03	1.556TyrArg: 1.556 ± 0.043	1.073TyrSer: 1.073 ± 0.036	1.123TyrThr: 1.123 ± 0.043	1.642TyrVal: 1.642 ± 0.042	0.325TyrTrp: 0.325 ± 0.018	0.489TyrTyr: 0.489 ± 0.028	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2531 proteins (839896 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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