Amino acid dipepetide frequency for Cephaloticoccus capnophilus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
17.304AlaAla: 17.304 ± 0.257
0.993AlaCys: 0.993 ± 0.044
5.729AlaAsp: 5.729 ± 0.106
7.938AlaGlu: 7.938 ± 0.168
3.74AlaPhe: 3.74 ± 0.086
8.64AlaGly: 8.64 ± 0.145
2.78AlaHis: 2.78 ± 0.07
5.401AlaIle: 5.401 ± 0.106
4.356AlaLys: 4.356 ± 0.109
14.125AlaLeu: 14.125 ± 0.2
2.166AlaMet: 2.166 ± 0.066
3.153AlaAsn: 3.153 ± 0.078
5.952AlaPro: 5.952 ± 0.118
5.515AlaGln: 5.515 ± 0.124
8.651AlaArg: 8.651 ± 0.152
6.6AlaSer: 6.6 ± 0.119
6.169AlaThr: 6.169 ± 0.12
7.256AlaVal: 7.256 ± 0.125
1.418AlaTrp: 1.418 ± 0.055
2.529AlaTyr: 2.529 ± 0.068
0.0AlaXaa: 0.0 ± 0.0
Cys
1.249CysAla: 1.249 ± 0.051
0.115CysCys: 0.115 ± 0.015
0.596CysAsp: 0.596 ± 0.036
0.61CysGlu: 0.61 ± 0.036
0.413CysPhe: 0.413 ± 0.026
0.942CysGly: 0.942 ± 0.044
0.208CysHis: 0.208 ± 0.023
0.42CysIle: 0.42 ± 0.025
0.188CysLys: 0.188 ± 0.018
0.862CysLeu: 0.862 ± 0.036
0.147CysMet: 0.147 ± 0.016
0.199CysAsn: 0.199 ± 0.018
0.51CysPro: 0.51 ± 0.031
0.235CysGln: 0.235 ± 0.024
0.556CysArg: 0.556 ± 0.031
0.477CysSer: 0.477 ± 0.029
0.438CysThr: 0.438 ± 0.029
0.696CysVal: 0.696 ± 0.041
0.133CysTrp: 0.133 ± 0.017
0.282CysTyr: 0.282 ± 0.023
0.0CysXaa: 0.0 ± 0.0
Asp
6.016AspAla: 6.016 ± 0.112
0.537AspCys: 0.537 ± 0.032
2.245AspAsp: 2.245 ± 0.063
3.331AspGlu: 3.331 ± 0.08
2.646AspPhe: 2.646 ± 0.069
3.976AspGly: 3.976 ± 0.084
1.046AspHis: 1.046 ± 0.052
2.54AspIle: 2.54 ± 0.067
1.671AspLys: 1.671 ± 0.061
5.173AspLeu: 5.173 ± 0.105
0.777AspMet: 0.777 ± 0.035
1.201AspAsn: 1.201 ± 0.054
2.637AspPro: 2.637 ± 0.079
1.413AspGln: 1.413 ± 0.052
3.179AspArg: 3.179 ± 0.08
2.909AspSer: 2.909 ± 0.068
2.759AspThr: 2.759 ± 0.076
2.836AspVal: 2.836 ± 0.072
0.944AspTrp: 0.944 ± 0.043
1.883AspTyr: 1.883 ± 0.055
0.0AspXaa: 0.0 ± 0.0
Glu
7.714GluAla: 7.714 ± 0.146
0.503GluCys: 0.503 ± 0.035
2.421GluAsp: 2.421 ± 0.063
3.225GluGlu: 3.225 ± 0.088
2.242GluPhe: 2.242 ± 0.07
4.257GluGly: 4.257 ± 0.091
1.393GluHis: 1.393 ± 0.051
3.782GluIle: 3.782 ± 0.083
2.707GluLys: 2.707 ± 0.081
7.213GluLeu: 7.213 ± 0.141
1.086GluMet: 1.086 ± 0.05
1.8GluAsn: 1.8 ± 0.058
2.847GluPro: 2.847 ± 0.071
2.493GluGln: 2.493 ± 0.078
4.842GluArg: 4.842 ± 0.112
3.155GluSer: 3.155 ± 0.084
3.259GluThr: 3.259 ± 0.084
4.281GluVal: 4.281 ± 0.096
0.818GluTrp: 0.818 ± 0.042
1.095GluTyr: 1.095 ± 0.051
0.0GluXaa: 0.0 ± 0.0
Phe
4.525PheAla: 4.525 ± 0.086
0.468PheCys: 0.468 ± 0.028
2.226PheAsp: 2.226 ± 0.063
2.33PheGlu: 2.33 ± 0.064
1.845PhePhe: 1.845 ± 0.072
3.428PheGly: 3.428 ± 0.09
0.689PheHis: 0.689 ± 0.034
1.894PheIle: 1.894 ± 0.055
1.33PheLys: 1.33 ± 0.05
3.699PheLeu: 3.699 ± 0.086
0.713PheMet: 0.713 ± 0.029
1.29PheAsn: 1.29 ± 0.05
1.628PhePro: 1.628 ± 0.057
1.046PheGln: 1.046 ± 0.046
2.222PheArg: 2.222 ± 0.061
2.692PheSer: 2.692 ± 0.068
2.331PheThr: 2.331 ± 0.066
2.708PheVal: 2.708 ± 0.059
0.571PheTrp: 0.571 ± 0.035
1.188PheTyr: 1.188 ± 0.049
0.0PheXaa: 0.0 ± 0.0
Gly
8.437GlyAla: 8.437 ± 0.15
0.808GlyCys: 0.808 ± 0.044
3.959GlyAsp: 3.959 ± 0.102
5.126GlyGlu: 5.126 ± 0.101
3.381GlyPhe: 3.381 ± 0.08
7.465GlyGly: 7.465 ± 0.198
1.802GlyHis: 1.802 ± 0.054
4.112GlyIle: 4.112 ± 0.102
3.107GlyLys: 3.107 ± 0.084
8.874GlyLeu: 8.874 ± 0.151
1.454GlyMet: 1.454 ± 0.053
2.208GlyAsn: 2.208 ± 0.076
3.073GlyPro: 3.073 ± 0.073
2.922GlyGln: 2.922 ± 0.07
5.621GlyArg: 5.621 ± 0.104
4.846GlySer: 4.846 ± 0.103
4.378GlyThr: 4.378 ± 0.103
5.415GlyVal: 5.415 ± 0.104
1.224GlyTrp: 1.224 ± 0.045
2.235GlyTyr: 2.235 ± 0.067
0.0GlyXaa: 0.0 ± 0.0
His
2.665HisAla: 2.665 ± 0.068
0.294HisCys: 0.294 ± 0.024
1.088HisAsp: 1.088 ± 0.042
1.282HisGlu: 1.282 ± 0.049
1.179HisPhe: 1.179 ± 0.045
1.897HisGly: 1.897 ± 0.059
0.538HisHis: 0.538 ± 0.039
1.106HisIle: 1.106 ± 0.041
0.634HisLys: 0.634 ± 0.031
2.287HisLeu: 2.287 ± 0.067
0.407HisMet: 0.407 ± 0.025
0.655HisAsn: 0.655 ± 0.037
1.405HisPro: 1.405 ± 0.057
0.63HisGln: 0.63 ± 0.036
1.391HisArg: 1.391 ± 0.062
1.391HisSer: 1.391 ± 0.058
1.255HisThr: 1.255 ± 0.056
1.206HisVal: 1.206 ± 0.046
0.45HisTrp: 0.45 ± 0.032
0.863HisTyr: 0.863 ± 0.044
0.0HisXaa: 0.0 ± 0.0
Ile
6.088IleAla: 6.088 ± 0.094
0.524IleCys: 0.524 ± 0.03
3.43IleAsp: 3.43 ± 0.079
3.66IleGlu: 3.66 ± 0.08
1.757IlePhe: 1.757 ± 0.063
4.317IleGly: 4.317 ± 0.099
1.048IleHis: 1.048 ± 0.049
2.421IleIle: 2.421 ± 0.079
1.666IleLys: 1.666 ± 0.055
4.58IleLeu: 4.58 ± 0.087
0.829IleMet: 0.829 ± 0.041
1.662IleAsn: 1.662 ± 0.061
2.461IlePro: 2.461 ± 0.062
1.423IleGln: 1.423 ± 0.047
3.01IleArg: 3.01 ± 0.084
2.895IleSer: 2.895 ± 0.079
3.042IleThr: 3.042 ± 0.075
3.52IleVal: 3.52 ± 0.087
0.495IleTrp: 0.495 ± 0.032
1.307IleTyr: 1.307 ± 0.053
0.0IleXaa: 0.0 ± 0.0
Lys
3.848LysAla: 3.848 ± 0.106
0.214LysCys: 0.214 ± 0.02
1.486LysAsp: 1.486 ± 0.066
1.705LysGlu: 1.705 ± 0.068
1.213LysPhe: 1.213 ± 0.047
2.416LysGly: 2.416 ± 0.075
0.878LysHis: 0.878 ± 0.045
2.066LysIle: 2.066 ± 0.072
1.874LysLys: 1.874 ± 0.085
3.949LysLeu: 3.949 ± 0.093
0.759LysMet: 0.759 ± 0.035
1.265LysAsn: 1.265 ± 0.051
2.051LysPro: 2.051 ± 0.066
1.129LysGln: 1.129 ± 0.053
2.509LysArg: 2.509 ± 0.067
1.953LysSer: 1.953 ± 0.067
2.552LysThr: 2.552 ± 0.086
2.312LysVal: 2.312 ± 0.082
0.436LysTrp: 0.436 ± 0.026
0.743LysTyr: 0.743 ± 0.037
0.0LysXaa: 0.0 ± 0.0
Leu
13.718LeuAla: 13.718 ± 0.199
1.305LeuCys: 1.305 ± 0.049
5.645LeuAsp: 5.645 ± 0.103
5.654LeuGlu: 5.654 ± 0.108
4.13LeuPhe: 4.13 ± 0.087
9.38LeuGly: 9.38 ± 0.143
2.541LeuHis: 2.541 ± 0.071
5.085LeuIle: 5.085 ± 0.107
3.758LeuLys: 3.758 ± 0.095
11.194LeuLeu: 11.194 ± 0.179
1.929LeuMet: 1.929 ± 0.068
2.897LeuAsn: 2.897 ± 0.08
6.018LeuPro: 6.018 ± 0.108
2.848LeuGln: 2.848 ± 0.066
8.653LeuArg: 8.653 ± 0.156
7.33LeuSer: 7.33 ± 0.126
5.611LeuThr: 5.611 ± 0.099
7.323LeuVal: 7.323 ± 0.124
1.328LeuTrp: 1.328 ± 0.058
2.554LeuTyr: 2.554 ± 0.077
0.0LeuXaa: 0.0 ± 0.0
Met
1.768MetAla: 1.768 ± 0.051
0.122MetCys: 0.122 ± 0.016
0.752MetAsp: 0.752 ± 0.043
0.942MetGlu: 0.942 ± 0.046
0.49MetPhe: 0.49 ± 0.034
1.314MetGly: 1.314 ± 0.052
0.382MetHis: 0.382 ± 0.024
1.003MetIle: 1.003 ± 0.04
0.822MetLys: 0.822 ± 0.04
1.973MetLeu: 1.973 ± 0.067
0.398MetMet: 0.398 ± 0.035
0.578MetAsn: 0.578 ± 0.032
1.167MetPro: 1.167 ± 0.052
0.695MetGln: 0.695 ± 0.032
1.384MetArg: 1.384 ± 0.047
1.303MetSer: 1.303 ± 0.049
1.154MetThr: 1.154 ± 0.043
1.002MetVal: 1.002 ± 0.04
0.142MetTrp: 0.142 ± 0.018
0.258MetTyr: 0.258 ± 0.021
0.0MetXaa: 0.0 ± 0.0
Asn
3.403AsnAla: 3.403 ± 0.078
0.23AsnCys: 0.23 ± 0.021
1.378AsnAsp: 1.378 ± 0.056
1.346AsnGlu: 1.346 ± 0.049
1.206AsnPhe: 1.206 ± 0.05
2.226AsnGly: 2.226 ± 0.081
0.571AsnHis: 0.571 ± 0.031
1.355AsnIle: 1.355 ± 0.061
0.903AsnLys: 0.903 ± 0.044
2.891AsnLeu: 2.891 ± 0.082
0.459AsnMet: 0.459 ± 0.029
0.86AsnAsn: 0.86 ± 0.049
2.005AsnPro: 2.005 ± 0.065
0.869AsnGln: 0.869 ± 0.046
2.05AsnArg: 2.05 ± 0.077
1.508AsnSer: 1.508 ± 0.062
1.73AsnThr: 1.73 ± 0.056
1.745AsnVal: 1.745 ± 0.057
0.501AsnTrp: 0.501 ± 0.033
0.973AsnTyr: 0.973 ± 0.045
0.0AsnXaa: 0.0 ± 0.0
Pro
5.901ProAla: 5.901 ± 0.125
0.37ProCys: 0.37 ± 0.026
3.008ProAsp: 3.008 ± 0.076
4.08ProGlu: 4.08 ± 0.087
1.85ProPhe: 1.85 ± 0.061
3.696ProGly: 3.696 ± 0.091
1.298ProHis: 1.298 ± 0.051
2.434ProIle: 2.434 ± 0.065
2.023ProLys: 2.023 ± 0.068
5.454ProLeu: 5.454 ± 0.101
0.827ProMet: 0.827 ± 0.041
1.615ProAsn: 1.615 ± 0.057
2.807ProPro: 2.807 ± 0.097
1.987ProGln: 1.987 ± 0.059
3.254ProArg: 3.254 ± 0.09
3.527ProSer: 3.527 ± 0.093
3.039ProThr: 3.039 ± 0.079
3.342ProVal: 3.342 ± 0.082
0.648ProTrp: 0.648 ± 0.031
1.217ProTyr: 1.217 ± 0.055
0.0ProXaa: 0.0 ± 0.0
Gln
3.931GlnAla: 3.931 ± 0.083
0.251GlnCys: 0.251 ± 0.024
1.229GlnAsp: 1.229 ± 0.048
1.558GlnGlu: 1.558 ± 0.053
1.328GlnPhe: 1.328 ± 0.048
2.165GlnGly: 2.165 ± 0.062
0.906GlnHis: 0.906 ± 0.039
2.2GlnIle: 2.2 ± 0.06
1.348GlnLys: 1.348 ± 0.052
3.923GlnLeu: 3.923 ± 0.097
0.765GlnMet: 0.765 ± 0.034
1.14GlnAsn: 1.14 ± 0.047
1.913GlnPro: 1.913 ± 0.066
1.312GlnGln: 1.312 ± 0.054
2.789GlnArg: 2.789 ± 0.084
2.093GlnSer: 2.093 ± 0.058
1.838GlnThr: 1.838 ± 0.049
2.689GlnVal: 2.689 ± 0.071
0.49GlnTrp: 0.49 ± 0.036
0.61GlnTyr: 0.61 ± 0.035
0.0GlnXaa: 0.0 ± 0.0
Arg
8.407ArgAla: 8.407 ± 0.139
0.578ArgCys: 0.578 ± 0.033
3.712ArgAsp: 3.712 ± 0.094
5.09ArgGlu: 5.09 ± 0.117
2.888ArgPhe: 2.888 ± 0.077
5.198ArgGly: 5.198 ± 0.099
1.667ArgHis: 1.667 ± 0.051
3.746ArgIle: 3.746 ± 0.075
2.319ArgLys: 2.319 ± 0.066
7.965ArgLeu: 7.965 ± 0.142
1.237ArgMet: 1.237 ± 0.046
1.759ArgAsn: 1.759 ± 0.062
3.311ArgPro: 3.311 ± 0.089
2.396ArgGln: 2.396 ± 0.071
5.153ArgArg: 5.153 ± 0.12
4.063ArgSer: 4.063 ± 0.105
3.078ArgThr: 3.078 ± 0.069
5.061ArgVal: 5.061 ± 0.106
0.908ArgTrp: 0.908 ± 0.041
2.251ArgTyr: 2.251 ± 0.066
0.0ArgXaa: 0.0 ± 0.0
Ser
7.199SerAla: 7.199 ± 0.125
0.459SerCys: 0.459 ± 0.031
2.958SerAsp: 2.958 ± 0.07
3.875SerGlu: 3.875 ± 0.086
2.355SerPhe: 2.355 ± 0.067
5.903SerGly: 5.903 ± 0.124
1.215SerHis: 1.215 ± 0.048
2.608SerIle: 2.608 ± 0.072
1.716SerLys: 1.716 ± 0.057
6.476SerLeu: 6.476 ± 0.118
1.014SerMet: 1.014 ± 0.042
1.436SerAsn: 1.436 ± 0.057
3.717SerPro: 3.717 ± 0.085
2.005SerGln: 2.005 ± 0.065
3.947SerArg: 3.947 ± 0.1
3.525SerSer: 3.525 ± 0.103
3.092SerThr: 3.092 ± 0.09
3.868SerVal: 3.868 ± 0.089
0.626SerTrp: 0.626 ± 0.039
1.682SerTyr: 1.682 ± 0.068
0.0SerXaa: 0.0 ± 0.0
Thr
6.289ThrAla: 6.289 ± 0.111
0.397ThrCys: 0.397 ± 0.028
2.375ThrAsp: 2.375 ± 0.063
2.791ThrGlu: 2.791 ± 0.076
1.763ThrPhe: 1.763 ± 0.061
4.72ThrGly: 4.72 ± 0.102
1.389ThrHis: 1.389 ± 0.053
2.705ThrIle: 2.705 ± 0.078
1.685ThrLys: 1.685 ± 0.053
7.23ThrLeu: 7.23 ± 0.109
0.818ThrMet: 0.818 ± 0.04
1.369ThrAsn: 1.369 ± 0.055
3.658ThrPro: 3.658 ± 0.088
1.865ThrGln: 1.865 ± 0.06
3.791ThrArg: 3.791 ± 0.089
3.076ThrSer: 3.076 ± 0.075
3.311ThrThr: 3.311 ± 0.084
3.561ThrVal: 3.561 ± 0.082
0.727ThrTrp: 0.727 ± 0.045
1.373ThrTyr: 1.373 ± 0.05
0.0ThrXaa: 0.0 ± 0.0
Val
7.603ValAla: 7.603 ± 0.151
0.72ValCys: 0.72 ± 0.04
3.27ValAsp: 3.27 ± 0.08
4.227ValGlu: 4.227 ± 0.09
2.775ValPhe: 2.775 ± 0.066
5.329ValGly: 5.329 ± 0.117
1.353ValHis: 1.353 ± 0.052
3.631ValIle: 3.631 ± 0.091
2.208ValLys: 2.208 ± 0.07
6.722ValLeu: 6.722 ± 0.122
1.215ValMet: 1.215 ± 0.049
1.926ValAsn: 1.926 ± 0.066
3.346ValPro: 3.346 ± 0.076
2.068ValGln: 2.068 ± 0.06
4.647ValArg: 4.647 ± 0.083
4.229ValSer: 4.229 ± 0.088
3.787ValThr: 3.787 ± 0.082
4.824ValVal: 4.824 ± 0.103
0.723ValTrp: 0.723 ± 0.035
1.579ValTyr: 1.579 ± 0.057
0.0ValXaa: 0.0 ± 0.0
Trp
1.436TrpAla: 1.436 ± 0.059
0.165TrpCys: 0.165 ± 0.019
0.702TrpAsp: 0.702 ± 0.033
0.842TrpGlu: 0.842 ± 0.04
0.51TrpPhe: 0.51 ± 0.034
0.962TrpGly: 0.962 ± 0.045
0.311TrpHis: 0.311 ± 0.025
0.547TrpIle: 0.547 ± 0.033
0.372TrpLys: 0.372 ± 0.029
1.678TrpLeu: 1.678 ± 0.062
0.285TrpMet: 0.285 ± 0.024
0.357TrpAsn: 0.357 ± 0.024
0.621TrpPro: 0.621 ± 0.033
0.625TrpGln: 0.625 ± 0.034
1.154TrpArg: 1.154 ± 0.046
0.741TrpSer: 0.741 ± 0.04
0.549TrpThr: 0.549 ± 0.034
0.862TrpVal: 0.862 ± 0.042
0.226TrpTrp: 0.226 ± 0.023
0.282TrpTyr: 0.282 ± 0.026
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.915TyrAla: 2.915 ± 0.083
0.226TyrCys: 0.226 ± 0.021
1.509TyrAsp: 1.509 ± 0.053
1.522TyrGlu: 1.522 ± 0.054
1.113TyrPhe: 1.113 ± 0.046
2.217TyrGly: 2.217 ± 0.066
0.607TyrHis: 0.607 ± 0.034
1.08TyrIle: 1.08 ± 0.047
0.673TyrLys: 0.673 ± 0.043
2.633TyrLeu: 2.633 ± 0.083
0.359TyrMet: 0.359 ± 0.027
0.836TyrAsn: 0.836 ± 0.044
1.251TyrPro: 1.251 ± 0.049
1.003TyrGln: 1.003 ± 0.049
1.985TyrArg: 1.985 ± 0.068
1.362TyrSer: 1.362 ± 0.047
1.52TyrThr: 1.52 ± 0.062
1.675TyrVal: 1.675 ± 0.062
0.416TyrTrp: 0.416 ± 0.029
0.793TyrTyr: 0.793 ± 0.044
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1549 proteins (557160 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski