Amino acid dipepetide frequency for Equus caballus papillomavirus 5

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.544AlaAla: 9.544 ± 1.722
2.075AlaCys: 2.075 ± 0.673
3.734AlaAsp: 3.734 ± 1.099
4.149AlaGlu: 4.149 ± 1.398
2.905AlaPhe: 2.905 ± 0.917
4.979AlaGly: 4.979 ± 1.232
1.66AlaHis: 1.66 ± 0.805
0.83AlaIle: 0.83 ± 0.425
2.905AlaLys: 2.905 ± 1.506
3.734AlaLeu: 3.734 ± 0.489
1.66AlaMet: 1.66 ± 0.576
2.075AlaAsn: 2.075 ± 0.905
7.469AlaPro: 7.469 ± 1.629
4.564AlaGln: 4.564 ± 2.009
7.054AlaArg: 7.054 ± 1.377
3.32AlaSer: 3.32 ± 0.496
3.32AlaThr: 3.32 ± 1.074
6.224AlaVal: 6.224 ± 1.385
1.245AlaTrp: 1.245 ± 0.835
3.734AlaTyr: 3.734 ± 0.778
0.0AlaXaa: 0.0 ± 0.0
Cys
1.66CysAla: 1.66 ± 0.74
0.415CysCys: 0.415 ± 0.358
0.415CysAsp: 0.415 ± 0.369
0.415CysGlu: 0.415 ± 0.358
0.83CysPhe: 0.83 ± 0.366
0.415CysGly: 0.415 ± 0.481
0.415CysHis: 0.415 ± 0.369
0.83CysIle: 0.83 ± 0.963
2.905CysLys: 2.905 ± 1.866
1.245CysLeu: 1.245 ± 0.894
0.83CysMet: 0.83 ± 0.614
0.415CysAsn: 0.415 ± 0.358
2.075CysPro: 2.075 ± 0.681
0.0CysGln: 0.0 ± 0.0
2.905CysArg: 2.905 ± 1.344
3.734CysSer: 3.734 ± 1.516
1.245CysThr: 1.245 ± 0.795
1.245CysVal: 1.245 ± 0.798
0.83CysTrp: 0.83 ± 0.353
1.245CysTyr: 1.245 ± 0.57
0.0CysXaa: 0.0 ± 0.0
Asp
5.394AspAla: 5.394 ± 0.893
1.245AspCys: 1.245 ± 0.523
2.075AspAsp: 2.075 ± 0.64
4.149AspGlu: 4.149 ± 1.745
1.66AspPhe: 1.66 ± 0.961
6.639AspGly: 6.639 ± 2.452
0.0AspHis: 0.0 ± 0.0
3.734AspIle: 3.734 ± 1.186
0.83AspLys: 0.83 ± 0.353
4.564AspLeu: 4.564 ± 1.416
0.83AspMet: 0.83 ± 0.353
2.905AspAsn: 2.905 ± 1.519
3.734AspPro: 3.734 ± 0.696
2.075AspGln: 2.075 ± 0.637
2.49AspArg: 2.49 ± 0.703
4.979AspSer: 4.979 ± 1.228
2.49AspThr: 2.49 ± 1.182
5.809AspVal: 5.809 ± 1.988
1.245AspTrp: 1.245 ± 0.63
2.075AspTyr: 2.075 ± 0.872
0.0AspXaa: 0.0 ± 0.0
Glu
7.884GluAla: 7.884 ± 2.055
0.83GluCys: 0.83 ± 0.738
4.149GluAsp: 4.149 ± 1.17
6.639GluGlu: 6.639 ± 1.268
0.83GluPhe: 0.83 ± 0.427
5.394GluGly: 5.394 ± 1.922
0.0GluHis: 0.0 ± 0.0
2.49GluIle: 2.49 ± 0.926
2.49GluLys: 2.49 ± 1.041
6.639GluLeu: 6.639 ± 0.85
1.66GluMet: 1.66 ± 0.583
1.66GluAsn: 1.66 ± 0.531
1.66GluPro: 1.66 ± 0.854
2.075GluGln: 2.075 ± 0.64
2.905GluArg: 2.905 ± 0.878
2.075GluSer: 2.075 ± 1.333
1.66GluThr: 1.66 ± 0.79
5.394GluVal: 5.394 ± 1.944
0.415GluTrp: 0.415 ± 0.358
2.49GluTyr: 2.49 ± 0.765
0.0GluXaa: 0.0 ± 0.0
Phe
2.075PheAla: 2.075 ± 0.396
0.415PheCys: 0.415 ± 0.481
2.49PheAsp: 2.49 ± 1.202
1.66PheGlu: 1.66 ± 0.713
2.905PhePhe: 2.905 ± 0.839
2.075PheGly: 2.075 ± 0.511
1.245PheHis: 1.245 ± 0.523
0.415PheIle: 0.415 ± 0.33
3.734PheLys: 3.734 ± 1.403
5.394PheLeu: 5.394 ± 0.757
0.415PheMet: 0.415 ± 0.358
2.075PheAsn: 2.075 ± 0.905
1.245PhePro: 1.245 ± 0.653
2.49PheGln: 2.49 ± 0.634
2.905PheArg: 2.905 ± 1.567
1.245PheSer: 1.245 ± 0.383
1.66PheThr: 1.66 ± 0.539
0.415PheVal: 0.415 ± 0.336
2.49PheTrp: 2.49 ± 0.821
3.734PheTyr: 3.734 ± 1.598
0.0PheXaa: 0.0 ± 0.0
Gly
3.734GlyAla: 3.734 ± 1.062
2.075GlyCys: 2.075 ± 0.728
6.639GlyAsp: 6.639 ± 1.309
4.564GlyGlu: 4.564 ± 1.325
1.245GlyPhe: 1.245 ± 0.5
13.278GlyGly: 13.278 ± 3.873
2.075GlyHis: 2.075 ± 0.511
2.075GlyIle: 2.075 ± 0.63
2.49GlyLys: 2.49 ± 0.752
4.564GlyLeu: 4.564 ± 1.977
0.83GlyMet: 0.83 ± 0.427
4.149GlyAsn: 4.149 ± 0.708
3.734GlyPro: 3.734 ± 1.302
5.809GlyGln: 5.809 ± 1.302
5.809GlyArg: 5.809 ± 2.681
4.564GlySer: 4.564 ± 1.419
5.394GlyThr: 5.394 ± 1.781
7.469GlyVal: 7.469 ± 2.617
0.415GlyTrp: 0.415 ± 0.369
2.075GlyTyr: 2.075 ± 0.913
0.0GlyXaa: 0.0 ± 0.0
His
2.075HisAla: 2.075 ± 0.601
0.0HisCys: 0.0 ± 0.0
0.83HisAsp: 0.83 ± 0.427
1.245HisGlu: 1.245 ± 0.582
1.245HisPhe: 1.245 ± 0.354
0.83HisGly: 0.83 ± 0.465
0.415HisHis: 0.415 ± 0.369
0.0HisIle: 0.0 ± 0.0
0.83HisLys: 0.83 ± 0.457
3.32HisLeu: 3.32 ± 1.328
0.0HisMet: 0.0 ± 0.0
0.415HisAsn: 0.415 ± 0.336
1.245HisPro: 1.245 ± 0.741
0.83HisGln: 0.83 ± 0.628
1.66HisArg: 1.66 ± 0.79
0.83HisSer: 0.83 ± 0.59
0.415HisThr: 0.415 ± 0.33
0.415HisVal: 0.415 ± 0.33
0.415HisTrp: 0.415 ± 0.358
0.415HisTyr: 0.415 ± 0.481
0.0HisXaa: 0.0 ± 0.0
Ile
1.66IleAla: 1.66 ± 0.972
1.245IleCys: 1.245 ± 0.788
2.075IleAsp: 2.075 ± 0.843
2.49IleGlu: 2.49 ± 1.144
2.075IlePhe: 2.075 ± 0.663
1.245IleGly: 1.245 ± 0.741
0.83IleHis: 0.83 ± 0.596
2.49IleIle: 2.49 ± 1.144
0.0IleLys: 0.0 ± 0.0
4.564IleLeu: 4.564 ± 1.416
0.0IleMet: 0.0 ± 0.0
0.83IleAsn: 0.83 ± 0.58
2.905IlePro: 2.905 ± 0.803
0.415IleGln: 0.415 ± 0.33
0.415IleArg: 0.415 ± 0.33
2.905IleSer: 2.905 ± 0.653
1.66IleThr: 1.66 ± 0.93
1.245IleVal: 1.245 ± 0.693
0.0IleTrp: 0.0 ± 0.0
0.83IleTyr: 0.83 ± 0.66
0.0IleXaa: 0.0 ± 0.0
Lys
1.66LysAla: 1.66 ± 0.89
0.415LysCys: 0.415 ± 0.481
1.66LysAsp: 1.66 ± 0.706
3.734LysGlu: 3.734 ± 0.744
2.075LysPhe: 2.075 ± 0.956
1.245LysGly: 1.245 ± 0.711
0.415LysHis: 0.415 ± 0.358
0.83LysIle: 0.83 ± 0.58
2.075LysLys: 2.075 ± 0.903
2.49LysLeu: 2.49 ± 1.417
0.83LysMet: 0.83 ± 0.345
1.66LysAsn: 1.66 ± 0.516
2.49LysPro: 2.49 ± 1.092
3.32LysGln: 3.32 ± 1.023
6.224LysArg: 6.224 ± 0.887
3.734LysSer: 3.734 ± 1.403
1.245LysThr: 1.245 ± 0.641
3.32LysVal: 3.32 ± 0.549
0.415LysTrp: 0.415 ± 0.336
1.245LysTyr: 1.245 ± 0.63
0.0LysXaa: 0.0 ± 0.0
Leu
6.224LeuAla: 6.224 ± 2.004
2.49LeuCys: 2.49 ± 1.014
5.394LeuAsp: 5.394 ± 1.438
4.564LeuGlu: 4.564 ± 1.244
3.32LeuPhe: 3.32 ± 0.936
7.469LeuGly: 7.469 ± 2.367
1.66LeuHis: 1.66 ± 0.713
0.83LeuIle: 0.83 ± 0.597
6.639LeuLys: 6.639 ± 2.621
5.809LeuLeu: 5.809 ± 2.1
1.245LeuMet: 1.245 ± 1.141
1.66LeuAsn: 1.66 ± 0.805
4.979LeuPro: 4.979 ± 0.806
4.564LeuGln: 4.564 ± 1.062
3.734LeuArg: 3.734 ± 0.787
9.544LeuSer: 9.544 ± 2.445
4.979LeuThr: 4.979 ± 1.749
5.809LeuVal: 5.809 ± 0.491
1.245LeuTrp: 1.245 ± 0.723
1.245LeuTyr: 1.245 ± 0.645
0.0LeuXaa: 0.0 ± 0.0
Met
2.075MetAla: 2.075 ± 0.663
0.0MetCys: 0.0 ± 0.0
2.075MetAsp: 2.075 ± 0.737
0.83MetGlu: 0.83 ± 0.427
0.415MetPhe: 0.415 ± 0.33
1.245MetGly: 1.245 ± 0.733
0.0MetHis: 0.0 ± 0.0
0.83MetIle: 0.83 ± 0.597
0.415MetLys: 0.415 ± 0.565
0.415MetLeu: 0.415 ± 0.358
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
1.245MetPro: 1.245 ± 0.693
0.415MetGln: 0.415 ± 0.358
1.245MetArg: 1.245 ± 0.894
1.245MetSer: 1.245 ± 0.693
1.245MetThr: 1.245 ± 0.627
1.66MetVal: 1.66 ± 0.972
0.415MetTrp: 0.415 ± 0.369
1.245MetTyr: 1.245 ± 0.832
0.0MetXaa: 0.0 ± 0.0
Asn
2.49AsnAla: 2.49 ± 0.931
0.415AsnCys: 0.415 ± 0.358
0.83AsnAsp: 0.83 ± 0.353
0.83AsnGlu: 0.83 ± 0.628
1.66AsnPhe: 1.66 ± 0.706
2.905AsnGly: 2.905 ± 0.829
0.83AsnHis: 0.83 ± 0.614
1.245AsnIle: 1.245 ± 0.354
2.075AsnLys: 2.075 ± 1.392
1.66AsnLeu: 1.66 ± 0.274
0.415AsnMet: 0.415 ± 0.33
2.075AsnAsn: 2.075 ± 0.905
4.979AsnPro: 4.979 ± 1.275
1.66AsnGln: 1.66 ± 0.747
2.905AsnArg: 2.905 ± 1.168
2.49AsnSer: 2.49 ± 0.664
1.245AsnThr: 1.245 ± 0.583
1.245AsnVal: 1.245 ± 0.582
0.415AsnTrp: 0.415 ± 0.358
1.245AsnTyr: 1.245 ± 0.668
0.0AsnXaa: 0.0 ± 0.0
Pro
5.394ProAla: 5.394 ± 1.438
2.905ProCys: 2.905 ± 1.108
4.979ProAsp: 4.979 ± 1.002
4.149ProGlu: 4.149 ± 0.891
2.905ProPhe: 2.905 ± 0.739
4.149ProGly: 4.149 ± 0.942
0.415ProHis: 0.415 ± 0.358
2.905ProIle: 2.905 ± 0.722
3.32ProLys: 3.32 ± 0.956
6.224ProLeu: 6.224 ± 1.465
0.415ProMet: 0.415 ± 0.53
2.075ProAsn: 2.075 ± 0.873
9.959ProPro: 9.959 ± 1.821
1.66ProGln: 1.66 ± 0.713
4.564ProArg: 4.564 ± 1.625
5.394ProSer: 5.394 ± 1.033
1.245ProThr: 1.245 ± 0.641
3.734ProVal: 3.734 ± 0.58
0.415ProTrp: 0.415 ± 0.369
1.245ProTyr: 1.245 ± 0.733
0.0ProXaa: 0.0 ± 0.0
Gln
2.905GlnAla: 2.905 ± 0.808
0.83GlnCys: 0.83 ± 0.647
2.905GlnAsp: 2.905 ± 1.001
2.49GlnGlu: 2.49 ± 0.821
2.075GlnPhe: 2.075 ± 0.938
3.32GlnGly: 3.32 ± 0.817
0.415GlnHis: 0.415 ± 0.369
0.83GlnIle: 0.83 ± 0.66
1.245GlnLys: 1.245 ± 0.63
3.734GlnLeu: 3.734 ± 1.084
2.075GlnMet: 2.075 ± 1.04
0.415GlnAsn: 0.415 ± 0.33
2.075GlnPro: 2.075 ± 1.03
0.83GlnGln: 0.83 ± 0.425
2.49GlnArg: 2.49 ± 1.15
2.905GlnSer: 2.905 ± 1.013
3.734GlnThr: 3.734 ± 1.328
3.734GlnVal: 3.734 ± 1.099
0.83GlnTrp: 0.83 ± 0.58
1.66GlnTyr: 1.66 ± 0.843
0.0GlnXaa: 0.0 ± 0.0
Arg
4.564ArgAla: 4.564 ± 1.013
2.49ArgCys: 2.49 ± 1.536
1.66ArgAsp: 1.66 ± 0.82
3.32ArgGlu: 3.32 ± 0.725
2.905ArgPhe: 2.905 ± 0.839
6.639ArgGly: 6.639 ± 1.577
1.245ArgHis: 1.245 ± 0.99
2.075ArgIle: 2.075 ± 0.696
3.32ArgLys: 3.32 ± 0.856
7.884ArgLeu: 7.884 ± 1.733
1.245ArgMet: 1.245 ± 0.593
3.32ArgAsn: 3.32 ± 1.184
4.564ArgPro: 4.564 ± 0.96
1.66ArgGln: 1.66 ± 1.294
7.469ArgArg: 7.469 ± 1.408
3.734ArgSer: 3.734 ± 1.043
4.149ArgThr: 4.149 ± 1.279
4.564ArgVal: 4.564 ± 2.247
1.245ArgTrp: 1.245 ± 0.827
4.564ArgTyr: 4.564 ± 1.073
0.0ArgXaa: 0.0 ± 0.0
Ser
7.054SerAla: 7.054 ± 1.714
0.0SerCys: 0.0 ± 0.0
4.564SerAsp: 4.564 ± 1.122
4.979SerGlu: 4.979 ± 1.065
2.905SerPhe: 2.905 ± 0.839
6.639SerGly: 6.639 ± 1.84
1.66SerHis: 1.66 ± 0.736
2.075SerIle: 2.075 ± 0.511
2.075SerLys: 2.075 ± 0.694
6.639SerLeu: 6.639 ± 1.084
1.66SerMet: 1.66 ± 0.457
2.49SerAsn: 2.49 ± 0.835
4.149SerPro: 4.149 ± 1.221
1.245SerGln: 1.245 ± 0.668
3.32SerArg: 3.32 ± 0.889
9.544SerSer: 9.544 ± 2.965
7.884SerThr: 7.884 ± 2.044
4.149SerVal: 4.149 ± 1.675
1.245SerTrp: 1.245 ± 0.693
0.83SerTyr: 0.83 ± 0.366
0.0SerXaa: 0.0 ± 0.0
Thr
2.49ThrAla: 2.49 ± 1.658
2.905ThrCys: 2.905 ± 0.972
3.32ThrAsp: 3.32 ± 1.017
2.905ThrGlu: 2.905 ± 0.841
2.075ThrPhe: 2.075 ± 1.461
4.564ThrGly: 4.564 ± 0.976
0.415ThrHis: 0.415 ± 0.358
2.075ThrIle: 2.075 ± 1.183
1.245ThrLys: 1.245 ± 0.611
4.149ThrLeu: 4.149 ± 0.942
1.245ThrMet: 1.245 ± 1.073
1.66ThrAsn: 1.66 ± 0.85
4.564ThrPro: 4.564 ± 0.789
2.905ThrGln: 2.905 ± 0.812
6.224ThrArg: 6.224 ± 1.799
4.564ThrSer: 4.564 ± 1.489
3.32ThrThr: 3.32 ± 0.716
4.564ThrVal: 4.564 ± 0.931
0.83ThrTrp: 0.83 ± 0.738
0.415ThrTyr: 0.415 ± 0.358
0.0ThrXaa: 0.0 ± 0.0
Val
4.979ValAla: 4.979 ± 1.213
2.075ValCys: 2.075 ± 1.114
7.054ValAsp: 7.054 ± 1.56
2.905ValGlu: 2.905 ± 1.505
3.734ValPhe: 3.734 ± 0.696
6.224ValGly: 6.224 ± 1.367
2.075ValHis: 2.075 ± 0.759
2.49ValIle: 2.49 ± 0.876
2.075ValLys: 2.075 ± 0.417
4.979ValLeu: 4.979 ± 1.692
0.415ValMet: 0.415 ± 0.358
1.245ValAsn: 1.245 ± 0.99
3.32ValPro: 3.32 ± 1.473
3.32ValGln: 3.32 ± 1.005
2.905ValArg: 2.905 ± 1.371
4.979ValSer: 4.979 ± 1.458
5.809ValThr: 5.809 ± 1.1
4.149ValVal: 4.149 ± 1.286
2.075ValTrp: 2.075 ± 0.813
1.245ValTyr: 1.245 ± 0.621
0.0ValXaa: 0.0 ± 0.0
Trp
0.83TrpAla: 0.83 ± 0.353
0.415TrpCys: 0.415 ± 0.53
0.83TrpAsp: 0.83 ± 0.715
1.66TrpGlu: 1.66 ± 0.805
0.415TrpPhe: 0.415 ± 0.358
1.66TrpGly: 1.66 ± 0.583
1.245TrpHis: 1.245 ± 0.811
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
2.075TrpLeu: 2.075 ± 0.843
0.415TrpMet: 0.415 ± 0.565
0.415TrpAsn: 0.415 ± 0.358
0.415TrpPro: 0.415 ± 0.565
0.415TrpGln: 0.415 ± 0.369
2.075TrpArg: 2.075 ± 1.096
1.66TrpSer: 1.66 ± 0.516
1.66TrpThr: 1.66 ± 0.614
1.66TrpVal: 1.66 ± 0.85
0.415TrpTrp: 0.415 ± 0.369
0.415TrpTyr: 0.415 ± 0.369
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.49TyrAla: 2.49 ± 0.774
0.83TyrCys: 0.83 ± 0.596
1.245TyrAsp: 1.245 ± 0.62
1.66TyrGlu: 1.66 ± 0.726
2.905TyrPhe: 2.905 ± 0.943
2.075TyrGly: 2.075 ± 0.623
0.415TyrHis: 0.415 ± 0.33
0.83TyrIle: 0.83 ± 0.66
0.83TyrLys: 0.83 ± 0.465
3.32TyrLeu: 3.32 ± 0.599
0.415TyrMet: 0.415 ± 0.318
2.075TyrAsn: 2.075 ± 1.322
1.245TyrPro: 1.245 ± 0.5
1.245TyrGln: 1.245 ± 1.073
3.32TyrArg: 3.32 ± 1.369
1.66TyrSer: 1.66 ± 0.805
2.075TyrThr: 2.075 ± 1.03
1.245TyrVal: 1.245 ± 0.63
2.075TyrTrp: 2.075 ± 1.248
1.66TyrTyr: 1.66 ± 0.55
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (2411 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski