Amino acid dipepetide frequency for Hubei sobemo-like virus 43

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.995AlaAla: 5.995 ± 0.828
3.597AlaCys: 3.597 ± 0.774
2.398AlaAsp: 2.398 ± 0.013
7.194AlaGlu: 7.194 ± 1.629
5.995AlaPhe: 5.995 ± 0.761
4.796AlaGly: 4.796 ± 1.615
3.597AlaHis: 3.597 ± 2.363
2.398AlaIle: 2.398 ± 0.013
5.995AlaLys: 5.995 ± 0.828
4.796AlaLeu: 4.796 ± 3.204
4.796AlaMet: 4.796 ± 1.292
1.199AlaAsn: 1.199 ± 0.801
2.398AlaPro: 2.398 ± 1.602
1.199AlaGln: 1.199 ± 0.801
4.796AlaArg: 4.796 ± 1.615
7.194AlaSer: 7.194 ± 1.629
2.398AlaThr: 2.398 ± 1.602
10.791AlaVal: 10.791 ± 0.734
2.398AlaTrp: 2.398 ± 1.575
4.796AlaTyr: 4.796 ± 1.562
0.0AlaXaa: 0.0 ± 0.0
Cys
1.199CysAla: 1.199 ± 0.801
0.0CysCys: 0.0 ± 0.0
1.199CysAsp: 1.199 ± 0.788
1.199CysGlu: 1.199 ± 0.788
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
3.597CysLeu: 3.597 ± 2.363
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.199CysPro: 1.199 ± 0.788
0.0CysGln: 0.0 ± 0.0
2.398CysArg: 2.398 ± 1.602
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
3.597CysVal: 3.597 ± 0.814
1.199CysTrp: 1.199 ± 0.801
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.199AspAla: 1.199 ± 0.788
0.0AspCys: 0.0 ± 0.0
2.398AspAsp: 2.398 ± 1.575
4.796AspGlu: 4.796 ± 1.615
1.199AspPhe: 1.199 ± 0.788
3.597AspGly: 3.597 ± 0.774
2.398AspHis: 2.398 ± 1.602
0.0AspIle: 0.0 ± 0.0
1.199AspLys: 1.199 ± 0.788
8.393AspLeu: 8.393 ± 0.748
2.398AspMet: 2.398 ± 0.013
0.0AspAsn: 0.0 ± 0.0
0.0AspPro: 0.0 ± 0.0
1.199AspGln: 1.199 ± 0.801
4.796AspArg: 4.796 ± 0.027
2.398AspSer: 2.398 ± 1.575
3.597AspThr: 3.597 ± 0.814
2.398AspVal: 2.398 ± 1.575
8.393AspTrp: 8.393 ± 0.748
2.398AspTyr: 2.398 ± 1.575
0.0AspXaa: 0.0 ± 0.0
Glu
2.398GluAla: 2.398 ± 0.013
2.398GluCys: 2.398 ± 1.602
1.199GluAsp: 1.199 ± 0.801
2.398GluGlu: 2.398 ± 0.013
2.398GluPhe: 2.398 ± 1.575
4.796GluGly: 4.796 ± 1.615
0.0GluHis: 0.0 ± 0.0
3.597GluIle: 3.597 ± 0.814
4.796GluLys: 4.796 ± 0.027
5.995GluLeu: 5.995 ± 0.761
0.0GluMet: 0.0 ± 0.0
0.0GluAsn: 0.0 ± 0.0
4.796GluPro: 4.796 ± 3.151
2.398GluGln: 2.398 ± 1.575
5.995GluArg: 5.995 ± 0.761
5.995GluSer: 5.995 ± 0.828
3.597GluThr: 3.597 ± 0.774
4.796GluVal: 4.796 ± 0.027
1.199GluTrp: 1.199 ± 0.801
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
2.398PheAla: 2.398 ± 0.013
0.0PheCys: 0.0 ± 0.0
1.199PheAsp: 1.199 ± 0.788
0.0PheGlu: 0.0 ± 0.0
1.199PhePhe: 1.199 ± 0.788
4.796PheGly: 4.796 ± 1.615
0.0PheHis: 0.0 ± 0.0
1.199PheIle: 1.199 ± 0.788
1.199PheLys: 1.199 ± 0.801
2.398PheLeu: 2.398 ± 1.575
2.398PheMet: 2.398 ± 1.602
1.199PheAsn: 1.199 ± 0.788
0.0PhePro: 0.0 ± 0.0
2.398PheGln: 2.398 ± 1.575
3.597PheArg: 3.597 ± 0.774
3.597PheSer: 3.597 ± 2.403
1.199PheThr: 1.199 ± 0.788
5.995PheVal: 5.995 ± 2.35
1.199PheTrp: 1.199 ± 0.788
2.398PheTyr: 2.398 ± 1.575
0.0PheXaa: 0.0 ± 0.0
Gly
11.99GlyAla: 11.99 ± 0.067
4.796GlyCys: 4.796 ± 0.027
3.597GlyAsp: 3.597 ± 0.774
4.796GlyGlu: 4.796 ± 0.027
2.398GlyPhe: 2.398 ± 0.013
5.995GlyGly: 5.995 ± 0.828
1.199GlyHis: 1.199 ± 0.788
3.597GlyIle: 3.597 ± 0.814
3.597GlyLys: 3.597 ± 2.403
8.393GlyLeu: 8.393 ± 0.748
2.398GlyMet: 2.398 ± 0.586
1.199GlyAsn: 1.199 ± 0.788
5.995GlyPro: 5.995 ± 0.761
1.199GlyGln: 1.199 ± 0.801
4.796GlyArg: 4.796 ± 1.562
7.194GlySer: 7.194 ± 4.806
4.796GlyThr: 4.796 ± 3.204
4.796GlyVal: 4.796 ± 0.027
2.398GlyTrp: 2.398 ± 0.013
4.796GlyTyr: 4.796 ± 1.615
0.0GlyXaa: 0.0 ± 0.0
His
3.597HisAla: 3.597 ± 0.774
1.199HisCys: 1.199 ± 0.788
0.0HisAsp: 0.0 ± 0.0
3.597HisGlu: 3.597 ± 0.774
3.597HisPhe: 3.597 ± 2.363
1.199HisGly: 1.199 ± 0.801
1.199HisHis: 1.199 ± 0.788
1.199HisIle: 1.199 ± 0.801
1.199HisLys: 1.199 ± 0.801
1.199HisLeu: 1.199 ± 0.801
2.398HisMet: 2.398 ± 0.013
1.199HisAsn: 1.199 ± 0.801
1.199HisPro: 1.199 ± 0.788
0.0HisGln: 0.0 ± 0.0
2.398HisArg: 2.398 ± 1.575
0.0HisSer: 0.0 ± 0.0
1.199HisThr: 1.199 ± 0.788
1.199HisVal: 1.199 ± 0.801
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
0.0IleAla: 0.0 ± 0.0
1.199IleCys: 1.199 ± 0.788
1.199IleAsp: 1.199 ± 0.788
1.199IleGlu: 1.199 ± 0.788
1.199IlePhe: 1.199 ± 0.788
4.796IleGly: 4.796 ± 1.615
1.199IleHis: 1.199 ± 0.801
2.398IleIle: 2.398 ± 0.013
2.398IleLys: 2.398 ± 0.013
1.199IleLeu: 1.199 ± 0.788
0.0IleMet: 0.0 ± 0.0
0.0IleAsn: 0.0 ± 0.0
0.0IlePro: 0.0 ± 0.0
1.199IleGln: 1.199 ± 0.788
2.398IleArg: 2.398 ± 1.602
2.398IleSer: 2.398 ± 1.575
1.199IleThr: 1.199 ± 0.801
1.199IleVal: 1.199 ± 0.801
0.0IleTrp: 0.0 ± 0.0
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
1.199LysAla: 1.199 ± 0.788
0.0LysCys: 0.0 ± 0.0
3.597LysAsp: 3.597 ± 0.814
1.199LysGlu: 1.199 ± 0.788
2.398LysPhe: 2.398 ± 0.013
3.597LysGly: 3.597 ± 2.403
3.597LysHis: 3.597 ± 0.814
1.199LysIle: 1.199 ± 0.801
0.0LysLys: 0.0 ± 0.0
3.597LysLeu: 3.597 ± 0.814
0.0LysMet: 0.0 ± 0.0
0.0LysAsn: 0.0 ± 0.0
1.199LysPro: 1.199 ± 0.801
1.199LysGln: 1.199 ± 0.801
3.597LysArg: 3.597 ± 0.814
4.796LysSer: 4.796 ± 1.562
2.398LysThr: 2.398 ± 0.013
2.398LysVal: 2.398 ± 0.013
0.0LysTrp: 0.0 ± 0.0
0.0LysTyr: 0.0 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
20.384LeuAla: 20.384 ± 0.908
0.0LeuCys: 0.0 ± 0.0
3.597LeuAsp: 3.597 ± 2.363
10.791LeuGlu: 10.791 ± 0.734
1.199LeuPhe: 1.199 ± 0.801
2.398LeuGly: 2.398 ± 0.013
4.796LeuHis: 4.796 ± 1.615
2.398LeuIle: 2.398 ± 1.575
4.796LeuLys: 4.796 ± 1.615
2.398LeuLeu: 2.398 ± 0.013
0.0LeuMet: 0.0 ± 0.0
1.199LeuAsn: 1.199 ± 0.788
8.393LeuPro: 8.393 ± 2.336
0.0LeuGln: 0.0 ± 0.0
9.592LeuArg: 9.592 ± 3.231
7.194LeuSer: 7.194 ± 1.549
3.597LeuThr: 3.597 ± 0.774
9.592LeuVal: 9.592 ± 3.231
2.398LeuTrp: 2.398 ± 1.575
3.597LeuTyr: 3.597 ± 2.363
0.0LeuXaa: 0.0 ± 0.0
Met
1.199MetAla: 1.199 ± 0.801
0.0MetCys: 0.0 ± 0.0
4.796MetAsp: 4.796 ± 0.027
1.199MetGlu: 1.199 ± 0.801
2.398MetPhe: 2.398 ± 1.602
0.0MetGly: 0.0 ± 0.0
1.199MetHis: 1.199 ± 0.788
0.0MetIle: 0.0 ± 0.0
1.199MetLys: 1.199 ± 0.788
1.199MetLeu: 1.199 ± 0.801
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
2.398MetPro: 2.398 ± 0.013
3.597MetGln: 3.597 ± 0.774
1.199MetArg: 1.199 ± 0.801
3.597MetSer: 3.597 ± 0.814
2.398MetThr: 2.398 ± 1.602
3.597MetVal: 3.597 ± 0.774
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.398AsnAla: 2.398 ± 1.602
0.0AsnCys: 0.0 ± 0.0
1.199AsnAsp: 1.199 ± 0.788
0.0AsnGlu: 0.0 ± 0.0
0.0AsnPhe: 0.0 ± 0.0
1.199AsnGly: 1.199 ± 0.788
1.199AsnHis: 1.199 ± 0.788
0.0AsnIle: 0.0 ± 0.0
0.0AsnLys: 0.0 ± 0.0
3.597AsnLeu: 3.597 ± 0.814
0.0AsnMet: 0.0 ± 0.0
0.0AsnAsn: 0.0 ± 0.0
2.398AsnPro: 2.398 ± 1.602
1.199AsnGln: 1.199 ± 0.801
1.199AsnArg: 1.199 ± 0.788
1.199AsnSer: 1.199 ± 0.788
1.199AsnThr: 1.199 ± 0.788
1.199AsnVal: 1.199 ± 0.788
0.0AsnTrp: 0.0 ± 0.0
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
2.398ProAla: 2.398 ± 1.602
0.0ProCys: 0.0 ± 0.0
3.597ProAsp: 3.597 ± 0.774
1.199ProGlu: 1.199 ± 0.801
0.0ProPhe: 0.0 ± 0.0
8.393ProGly: 8.393 ± 0.748
1.199ProHis: 1.199 ± 0.788
0.0ProIle: 0.0 ± 0.0
1.199ProLys: 1.199 ± 0.801
5.995ProLeu: 5.995 ± 2.35
1.199ProMet: 1.199 ± 0.801
3.597ProAsn: 3.597 ± 0.814
3.597ProPro: 3.597 ± 0.814
0.0ProGln: 0.0 ± 0.0
2.398ProArg: 2.398 ± 1.575
8.393ProSer: 8.393 ± 0.748
3.597ProThr: 3.597 ± 0.814
3.597ProVal: 3.597 ± 0.774
0.0ProTrp: 0.0 ± 0.0
1.199ProTyr: 1.199 ± 0.788
0.0ProXaa: 0.0 ± 0.0
Gln
1.199GlnAla: 1.199 ± 0.801
0.0GlnCys: 0.0 ± 0.0
1.199GlnAsp: 1.199 ± 0.801
0.0GlnGlu: 0.0 ± 0.0
0.0GlnPhe: 0.0 ± 0.0
2.398GlnGly: 2.398 ± 0.013
0.0GlnHis: 0.0 ± 0.0
0.0GlnIle: 0.0 ± 0.0
1.199GlnLys: 1.199 ± 0.788
9.592GlnLeu: 9.592 ± 3.231
0.0GlnMet: 0.0 ± 0.0
0.0GlnAsn: 0.0 ± 0.0
0.0GlnPro: 0.0 ± 0.0
2.398GlnGln: 2.398 ± 1.575
1.199GlnArg: 1.199 ± 0.788
1.199GlnSer: 1.199 ± 0.788
1.199GlnThr: 1.199 ± 0.788
2.398GlnVal: 2.398 ± 1.575
0.0GlnTrp: 0.0 ± 0.0
1.199GlnTyr: 1.199 ± 0.788
0.0GlnXaa: 0.0 ± 0.0
Arg
3.597ArgAla: 3.597 ± 2.403
0.0ArgCys: 0.0 ± 0.0
3.597ArgAsp: 3.597 ± 0.774
5.995ArgGlu: 5.995 ± 0.761
4.796ArgPhe: 4.796 ± 0.027
4.796ArgGly: 4.796 ± 3.151
1.199ArgHis: 1.199 ± 0.788
3.597ArgIle: 3.597 ± 0.814
1.199ArgLys: 1.199 ± 0.801
9.592ArgLeu: 9.592 ± 1.535
1.199ArgMet: 1.199 ± 0.801
1.199ArgAsn: 1.199 ± 0.801
3.597ArgPro: 3.597 ± 2.403
3.597ArgGln: 3.597 ± 0.774
5.995ArgArg: 5.995 ± 2.416
4.796ArgSer: 4.796 ± 1.615
1.199ArgThr: 1.199 ± 0.788
7.194ArgVal: 7.194 ± 1.629
4.796ArgTrp: 4.796 ± 3.151
3.597ArgTyr: 3.597 ± 0.774
0.0ArgXaa: 0.0 ± 0.0
Ser
10.791SerAla: 10.791 ± 2.443
1.199SerCys: 1.199 ± 0.801
3.597SerAsp: 3.597 ± 0.814
5.995SerGlu: 5.995 ± 0.828
3.597SerPhe: 3.597 ± 0.814
11.99SerGly: 11.99 ± 0.067
1.199SerHis: 1.199 ± 0.788
0.0SerIle: 0.0 ± 0.0
0.0SerLys: 0.0 ± 0.0
5.995SerLeu: 5.995 ± 2.35
4.796SerMet: 4.796 ± 1.562
3.597SerAsn: 3.597 ± 0.774
2.398SerPro: 2.398 ± 0.013
0.0SerGln: 0.0 ± 0.0
4.796SerArg: 4.796 ± 1.615
8.393SerSer: 8.393 ± 2.336
2.398SerThr: 2.398 ± 0.013
2.398SerVal: 2.398 ± 1.602
1.199SerTrp: 1.199 ± 0.801
1.199SerTyr: 1.199 ± 0.801
0.0SerXaa: 0.0 ± 0.0
Thr
5.995ThrAla: 5.995 ± 0.828
0.0ThrCys: 0.0 ± 0.0
2.398ThrAsp: 2.398 ± 1.602
1.199ThrGlu: 1.199 ± 0.788
1.199ThrPhe: 1.199 ± 0.801
7.194ThrGly: 7.194 ± 0.04
1.199ThrHis: 1.199 ± 0.788
2.398ThrIle: 2.398 ± 1.575
0.0ThrLys: 0.0 ± 0.0
7.194ThrLeu: 7.194 ± 1.629
3.597ThrMet: 3.597 ± 0.814
0.0ThrAsn: 0.0 ± 0.0
3.597ThrPro: 3.597 ± 0.774
1.199ThrGln: 1.199 ± 0.801
0.0ThrArg: 0.0 ± 0.0
0.0ThrSer: 0.0 ± 0.0
2.398ThrThr: 2.398 ± 1.602
4.796ThrVal: 4.796 ± 1.615
0.0ThrTrp: 0.0 ± 0.0
2.398ThrTyr: 2.398 ± 0.013
0.0ThrXaa: 0.0 ± 0.0
Val
5.995ValAla: 5.995 ± 0.761
0.0ValCys: 0.0 ± 0.0
7.194ValAsp: 7.194 ± 1.629
3.597ValGlu: 3.597 ± 0.774
3.597ValPhe: 3.597 ± 2.363
14.388ValGly: 14.388 ± 3.257
1.199ValHis: 1.199 ± 0.788
1.199ValIle: 1.199 ± 0.788
4.796ValLys: 4.796 ± 0.027
5.995ValLeu: 5.995 ± 0.828
2.398ValMet: 2.398 ± 0.013
2.398ValAsn: 2.398 ± 0.013
5.995ValPro: 5.995 ± 0.828
1.199ValGln: 1.199 ± 0.801
3.597ValArg: 3.597 ± 0.774
1.199ValSer: 1.199 ± 0.801
3.597ValThr: 3.597 ± 0.814
8.393ValVal: 8.393 ± 2.43
1.199ValTrp: 1.199 ± 0.788
4.796ValTyr: 4.796 ± 0.027
0.0ValXaa: 0.0 ± 0.0
Trp
1.199TrpAla: 1.199 ± 0.801
0.0TrpCys: 0.0 ± 0.0
1.199TrpAsp: 1.199 ± 0.788
0.0TrpGlu: 0.0 ± 0.0
1.199TrpPhe: 1.199 ± 0.788
1.199TrpGly: 1.199 ± 0.801
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.199TrpLys: 1.199 ± 0.788
7.194TrpLeu: 7.194 ± 1.549
0.0TrpMet: 0.0 ± 0.0
1.199TrpAsn: 1.199 ± 0.788
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
5.995TrpArg: 5.995 ± 0.761
0.0TrpSer: 0.0 ± 0.0
3.597TrpThr: 3.597 ± 0.774
0.0TrpVal: 0.0 ± 0.0
1.199TrpTrp: 1.199 ± 0.801
2.398TrpTyr: 2.398 ± 1.575
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.597TyrAla: 3.597 ± 0.774
1.199TyrCys: 1.199 ± 0.788
3.597TyrAsp: 3.597 ± 2.363
2.398TyrGlu: 2.398 ± 1.575
0.0TyrPhe: 0.0 ± 0.0
3.597TyrGly: 3.597 ± 0.774
1.199TyrHis: 1.199 ± 0.801
0.0TyrIle: 0.0 ± 0.0
0.0TyrLys: 0.0 ± 0.0
0.0TyrLeu: 0.0 ± 0.0
1.199TyrMet: 1.199 ± 0.801
0.0TyrAsn: 0.0 ± 0.0
2.398TyrPro: 2.398 ± 1.575
1.199TyrGln: 1.199 ± 0.788
4.796TyrArg: 4.796 ± 3.151
5.995TyrSer: 5.995 ± 0.828
1.199TyrThr: 1.199 ± 0.801
2.398TyrVal: 2.398 ± 0.013
0.0TyrTrp: 0.0 ± 0.0
1.199TyrTyr: 1.199 ± 0.788
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (835 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski