Amino acid dipepetide frequency for Lentzea aerocolonigenes (Lechevalieria aerocolonigenes) (Saccharothrix aerocolonigenes)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.375AlaAla: 17.375 ± 0.131	1.028AlaCys: 1.028 ± 0.022	7.435AlaAsp: 7.435 ± 0.053	8.069AlaGlu: 8.069 ± 0.079	3.693AlaPhe: 3.693 ± 0.039	11.39AlaGly: 11.39 ± 0.075	2.497AlaHis: 2.497 ± 0.034	4.253AlaIle: 4.253 ± 0.048	3.361AlaLys: 3.361 ± 0.052	13.391AlaLeu: 13.391 ± 0.104	2.55AlaMet: 2.55 ± 0.032	2.582AlaAsn: 2.582 ± 0.035	5.426AlaPro: 5.426 ± 0.058	3.869AlaGln: 3.869 ± 0.041	8.349AlaArg: 8.349 ± 0.076	6.315AlaSer: 6.315 ± 0.053	6.657AlaThr: 6.657 ± 0.059	11.549AlaVal: 11.549 ± 0.084	1.822AlaTrp: 1.822 ± 0.026	2.278AlaTyr: 2.278 ± 0.032	0.0AlaXaa: 0.0 ± 0.0
Cys	1.006CysAla: 1.006 ± 0.021	0.096CysCys: 0.096 ± 0.006	0.481CysAsp: 0.481 ± 0.013	0.404CysGlu: 0.404 ± 0.013	0.227CysPhe: 0.227 ± 0.008	0.956CysGly: 0.956 ± 0.02	0.188CysHis: 0.188 ± 0.009	0.189CysIle: 0.189 ± 0.008	0.143CysLys: 0.143 ± 0.009	0.741CysLeu: 0.741 ± 0.02	0.139CysMet: 0.139 ± 0.007	0.181CysAsn: 0.181 ± 0.009	0.479CysPro: 0.479 ± 0.015	0.22CysGln: 0.22 ± 0.009	0.553CysArg: 0.553 ± 0.013	0.512CysSer: 0.512 ± 0.014	0.541CysThr: 0.541 ± 0.016	0.696CysVal: 0.696 ± 0.018	0.123CysTrp: 0.123 ± 0.006	0.166CysTyr: 0.166 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	6.88AspAla: 6.88 ± 0.062	0.409AspCys: 0.409 ± 0.013	3.643AspAsp: 3.643 ± 0.046	4.1AspGlu: 4.1 ± 0.044	1.824AspPhe: 1.824 ± 0.028	6.021AspGly: 6.021 ± 0.07	1.44AspHis: 1.44 ± 0.023	1.942AspIle: 1.942 ± 0.027	1.36AspLys: 1.36 ± 0.027	6.517AspLeu: 6.517 ± 0.054	0.818AspMet: 0.818 ± 0.02	1.285AspAsn: 1.285 ± 0.025	3.927AspPro: 3.927 ± 0.041	1.856AspGln: 1.856 ± 0.027	4.304AspArg: 4.304 ± 0.045	2.737AspSer: 2.737 ± 0.04	2.848AspThr: 2.848 ± 0.036	5.795AspVal: 5.795 ± 0.052	1.006AspTrp: 1.006 ± 0.022	1.217AspTyr: 1.217 ± 0.024	0.0AspXaa: 0.0 ± 0.0
Glu	6.619GluAla: 6.619 ± 0.065	0.367GluCys: 0.367 ± 0.013	2.711GluAsp: 2.711 ± 0.034	3.06GluGlu: 3.06 ± 0.047	1.881GluPhe: 1.881 ± 0.03	3.592GluGly: 3.592 ± 0.043	1.657GluHis: 1.657 ± 0.025	2.732GluIle: 2.732 ± 0.033	1.606GluLys: 1.606 ± 0.028	7.173GluLeu: 7.173 ± 0.062	1.051GluMet: 1.051 ± 0.02	1.306GluAsn: 1.306 ± 0.025	3.188GluPro: 3.188 ± 0.042	2.422GluGln: 2.422 ± 0.035	4.621GluArg: 4.621 ± 0.054	2.645GluSer: 2.645 ± 0.035	2.737GluThr: 2.737 ± 0.034	5.067GluVal: 5.067 ± 0.052	0.86GluTrp: 0.86 ± 0.019	1.069GluTyr: 1.069 ± 0.023	0.0GluXaa: 0.0 ± 0.0
Phe	3.897PheAla: 3.897 ± 0.04	0.299PheCys: 0.299 ± 0.012	2.293PheAsp: 2.293 ± 0.03	1.701PheGlu: 1.701 ± 0.028	0.972PhePhe: 0.972 ± 0.022	3.408PheGly: 3.408 ± 0.044	0.696PheHis: 0.696 ± 0.018	0.86PheIle: 0.86 ± 0.02	0.655PheLys: 0.655 ± 0.02	2.807PheLeu: 2.807 ± 0.037	0.424PheMet: 0.424 ± 0.013	0.719PheAsn: 0.719 ± 0.019	1.425PhePro: 1.425 ± 0.021	0.85PheGln: 0.85 ± 0.023	1.945PheArg: 1.945 ± 0.03	1.855PheSer: 1.855 ± 0.029	2.155PheThr: 2.155 ± 0.029	2.779PheVal: 2.779 ± 0.039	0.496PheTrp: 0.496 ± 0.013	0.7PheTyr: 0.7 ± 0.017	0.0PheXaa: 0.0 ± 0.0
Gly	9.305GlyAla: 9.305 ± 0.068	0.816GlyCys: 0.816 ± 0.022	4.943GlyAsp: 4.943 ± 0.05	4.845GlyGlu: 4.845 ± 0.046	3.118GlyPhe: 3.118 ± 0.041	7.736GlyGly: 7.736 ± 0.09	2.042GlyHis: 2.042 ± 0.028	3.586GlyIle: 3.586 ± 0.046	2.931GlyLys: 2.931 ± 0.044	8.897GlyLeu: 8.897 ± 0.071	1.967GlyMet: 1.967 ± 0.03	2.156GlyAsn: 2.156 ± 0.037	4.216GlyPro: 4.216 ± 0.046	2.855GlyGln: 2.855 ± 0.034	6.074GlyArg: 6.074 ± 0.064	5.266GlySer: 5.266 ± 0.06	5.851GlyThr: 5.851 ± 0.057	8.103GlyVal: 8.103 ± 0.06	1.676GlyTrp: 1.676 ± 0.024	2.277GlyTyr: 2.277 ± 0.031	0.0GlyXaa: 0.0 ± 0.0
His	2.536HisAla: 2.536 ± 0.037	0.204HisCys: 0.204 ± 0.008	1.482HisAsp: 1.482 ± 0.029	1.291HisGlu: 1.291 ± 0.024	0.672HisPhe: 0.672 ± 0.016	2.199HisGly: 2.199 ± 0.033	0.653HisHis: 0.653 ± 0.018	0.64HisIle: 0.64 ± 0.017	0.422HisLys: 0.422 ± 0.013	2.35HisLeu: 2.35 ± 0.037	0.303HisMet: 0.303 ± 0.011	0.501HisAsn: 0.501 ± 0.015	1.52HisPro: 1.52 ± 0.027	0.704HisGln: 0.704 ± 0.016	1.786HisArg: 1.786 ± 0.027	1.056HisSer: 1.056 ± 0.021	1.169HisThr: 1.169 ± 0.024	2.045HisVal: 2.045 ± 0.03	0.367HisTrp: 0.367 ± 0.012	0.49HisTyr: 0.49 ± 0.017	0.0HisXaa: 0.0 ± 0.0
Ile	5.417IleAla: 5.417 ± 0.045	0.322IleCys: 0.322 ± 0.012	2.556IleAsp: 2.556 ± 0.035	2.215IleGlu: 2.215 ± 0.032	0.871IlePhe: 0.871 ± 0.019	3.901IleGly: 3.901 ± 0.054	0.636IleHis: 0.636 ± 0.014	1.125IleIle: 1.125 ± 0.023	0.999IleLys: 0.999 ± 0.021	2.331IleLeu: 2.331 ± 0.036	0.541IleMet: 0.541 ± 0.016	0.972IleAsn: 0.972 ± 0.02	1.917IlePro: 1.917 ± 0.03	0.828IleGln: 0.828 ± 0.02	2.338IleArg: 2.338 ± 0.029	2.246IleSer: 2.246 ± 0.031	2.806IleThr: 2.806 ± 0.032	3.206IleVal: 3.206 ± 0.043	0.449IleTrp: 0.449 ± 0.013	0.709IleTyr: 0.709 ± 0.018	0.0IleXaa: 0.0 ± 0.0
Lys	3.448LysAla: 3.448 ± 0.047	0.165LysCys: 0.165 ± 0.008	1.425LysAsp: 1.425 ± 0.031	1.193LysGlu: 1.193 ± 0.023	0.823LysPhe: 0.823 ± 0.022	1.857LysGly: 1.857 ± 0.033	0.61LysHis: 0.61 ± 0.015	1.238LysIle: 1.238 ± 0.027	0.857LysLys: 0.857 ± 0.021	2.774LysLeu: 2.774 ± 0.036	0.504LysMet: 0.504 ± 0.015	0.642LysAsn: 0.642 ± 0.018	1.758LysPro: 1.758 ± 0.033	0.933LysGln: 0.933 ± 0.02	1.674LysArg: 1.674 ± 0.029	1.411LysSer: 1.411 ± 0.026	1.545LysThr: 1.545 ± 0.031	2.341LysVal: 2.341 ± 0.036	0.437LysTrp: 0.437 ± 0.015	0.59LysTyr: 0.59 ± 0.016	0.0LysXaa: 0.0 ± 0.0
Leu	14.049LeuAla: 14.049 ± 0.104	0.812LeuCys: 0.812 ± 0.019	6.723LeuAsp: 6.723 ± 0.061	4.972LeuGlu: 4.972 ± 0.055	2.816LeuPhe: 2.816 ± 0.041	8.919LeuGly: 8.919 ± 0.076	2.326LeuHis: 2.326 ± 0.034	3.585LeuIle: 3.585 ± 0.046	2.591LeuLys: 2.591 ± 0.038	10.626LeuLeu: 10.626 ± 0.109	1.716LeuMet: 1.716 ± 0.027	2.132LeuAsn: 2.132 ± 0.033	5.965LeuPro: 5.965 ± 0.054	2.55LeuGln: 2.55 ± 0.032	8.112LeuArg: 8.112 ± 0.073	5.753LeuSer: 5.753 ± 0.046	6.629LeuThr: 6.629 ± 0.053	9.704LeuVal: 9.704 ± 0.076	1.343LeuTrp: 1.343 ± 0.027	1.73LeuTyr: 1.73 ± 0.026	0.0LeuXaa: 0.0 ± 0.0
Met	2.159MetAla: 2.159 ± 0.027	0.143MetCys: 0.143 ± 0.008	0.903MetAsp: 0.903 ± 0.019	0.707MetGlu: 0.707 ± 0.017	0.564MetPhe: 0.564 ± 0.017	1.281MetGly: 1.281 ± 0.021	0.386MetHis: 0.386 ± 0.013	0.842MetIle: 0.842 ± 0.015	0.563MetLys: 0.563 ± 0.017	1.887MetLeu: 1.887 ± 0.03	0.315MetMet: 0.315 ± 0.011	0.491MetAsn: 0.491 ± 0.013	1.128MetPro: 1.128 ± 0.022	0.502MetGln: 0.502 ± 0.016	1.585MetArg: 1.585 ± 0.026	1.402MetSer: 1.402 ± 0.021	1.544MetThr: 1.544 ± 0.021	1.4MetVal: 1.4 ± 0.025	0.262MetTrp: 0.262 ± 0.01	0.302MetTyr: 0.302 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	2.822AsnAla: 2.822 ± 0.039	0.206AsnCys: 0.206 ± 0.01	1.326AsnAsp: 1.326 ± 0.027	1.119AsnGlu: 1.119 ± 0.02	0.647AsnPhe: 0.647 ± 0.013	2.637AsnGly: 2.637 ± 0.045	0.449AsnHis: 0.449 ± 0.013	0.791AsnIle: 0.791 ± 0.018	0.572AsnLys: 0.572 ± 0.017	2.112AsnLeu: 2.112 ± 0.031	0.349AsnMet: 0.349 ± 0.012	0.712AsnAsn: 0.712 ± 0.023	1.716AsnPro: 1.716 ± 0.029	0.7AsnGln: 0.7 ± 0.019	1.512AsnArg: 1.512 ± 0.027	1.243AsnSer: 1.243 ± 0.027	1.347AsnThr: 1.347 ± 0.026	1.919AsnVal: 1.919 ± 0.033	0.394AsnTrp: 0.394 ± 0.013	0.574AsnTyr: 0.574 ± 0.018	0.0AsnXaa: 0.0 ± 0.0
Pro	7.011ProAla: 7.011 ± 0.068	0.356ProCys: 0.356 ± 0.012	4.074ProAsp: 4.074 ± 0.041	3.808ProGlu: 3.808 ± 0.043	1.686ProPhe: 1.686 ± 0.025	5.482ProGly: 5.482 ± 0.055	1.198ProHis: 1.198 ± 0.025	1.673ProIle: 1.673 ± 0.029	1.386ProLys: 1.386 ± 0.028	4.852ProLeu: 4.852 ± 0.046	1.033ProMet: 1.033 ± 0.022	1.31ProAsn: 1.31 ± 0.026	2.954ProPro: 2.954 ± 0.053	1.74ProGln: 1.74 ± 0.031	3.176ProArg: 3.176 ± 0.037	3.322ProSer: 3.322 ± 0.041	2.859ProThr: 2.859 ± 0.038	5.196ProVal: 5.196 ± 0.056	0.89ProTrp: 0.89 ± 0.022	1.049ProTyr: 1.049 ± 0.02	0.0ProXaa: 0.0 ± 0.0
Gln	3.863GlnAla: 3.863 ± 0.045	0.215GlnCys: 0.215 ± 0.009	1.539GlnAsp: 1.539 ± 0.026	1.513GlnGlu: 1.513 ± 0.026	0.964GlnPhe: 0.964 ± 0.02	2.252GlnGly: 2.252 ± 0.032	0.742GlnHis: 0.742 ± 0.02	1.282GlnIle: 1.282 ± 0.022	0.805GlnLys: 0.805 ± 0.019	3.415GlnLeu: 3.415 ± 0.04	0.561GlnMet: 0.561 ± 0.017	0.724GlnAsn: 0.724 ± 0.018	1.851GlnPro: 1.851 ± 0.029	1.491GlnGln: 1.491 ± 0.031	2.622GlnArg: 2.622 ± 0.035	1.449GlnSer: 1.449 ± 0.026	1.506GlnThr: 1.506 ± 0.025	2.85GlnVal: 2.85 ± 0.033	0.604GlnTrp: 0.604 ± 0.019	0.641GlnTyr: 0.641 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	8.177ArgAla: 8.177 ± 0.068	0.56ArgCys: 0.56 ± 0.017	4.018ArgAsp: 4.018 ± 0.049	4.318ArgGlu: 4.318 ± 0.048	2.415ArgPhe: 2.415 ± 0.032	5.167ArgGly: 5.167 ± 0.05	1.707ArgHis: 1.707 ± 0.027	3.01ArgIle: 3.01 ± 0.033	2.053ArgLys: 2.053 ± 0.031	7.657ArgLeu: 7.657 ± 0.074	1.793ArgMet: 1.793 ± 0.03	1.674ArgAsn: 1.674 ± 0.026	3.704ArgPro: 3.704 ± 0.039	2.364ArgGln: 2.364 ± 0.034	5.968ArgArg: 5.968 ± 0.06	3.903ArgSer: 3.903 ± 0.038	4.569ArgThr: 4.569 ± 0.047	5.781ArgVal: 5.781 ± 0.047	1.361ArgTrp: 1.361 ± 0.024	1.734ArgTyr: 1.734 ± 0.026	0.0ArgXaa: 0.0 ± 0.0
Ser	6.746SerAla: 6.746 ± 0.06	0.502SerCys: 0.502 ± 0.014	3.001SerAsp: 3.001 ± 0.039	2.672SerGlu: 2.672 ± 0.033	1.85SerPhe: 1.85 ± 0.03	6.107SerGly: 6.107 ± 0.061	1.068SerHis: 1.068 ± 0.017	1.893SerIle: 1.893 ± 0.032	1.365SerLys: 1.365 ± 0.026	5.471SerLeu: 5.471 ± 0.046	1.19SerMet: 1.19 ± 0.021	1.267SerAsn: 1.267 ± 0.027	3.079SerPro: 3.079 ± 0.037	1.486SerGln: 1.486 ± 0.024	3.727SerArg: 3.727 ± 0.041	3.681SerSer: 3.681 ± 0.049	3.57SerThr: 3.57 ± 0.044	4.847SerVal: 4.847 ± 0.049	1.064SerTrp: 1.064 ± 0.024	1.313SerTyr: 1.313 ± 0.026	0.0SerXaa: 0.0 ± 0.0
Thr	7.643ThrAla: 7.643 ± 0.059	0.504ThrCys: 0.504 ± 0.015	3.315ThrAsp: 3.315 ± 0.037	3.106ThrGlu: 3.106 ± 0.035	1.948ThrPhe: 1.948 ± 0.03	6.17ThrGly: 6.17 ± 0.068	1.164ThrHis: 1.164 ± 0.02	2.262ThrIle: 2.262 ± 0.035	1.544ThrLys: 1.544 ± 0.029	5.442ThrLeu: 5.442 ± 0.045	1.043ThrMet: 1.043 ± 0.022	1.444ThrAsn: 1.444 ± 0.029	3.804ThrPro: 3.804 ± 0.048	1.507ThrGln: 1.507 ± 0.026	3.659ThrArg: 3.659 ± 0.039	3.734ThrSer: 3.734 ± 0.045	4.215ThrThr: 4.215 ± 0.06	5.753ThrVal: 5.753 ± 0.046	1.044ThrTrp: 1.044 ± 0.022	1.341ThrTyr: 1.341 ± 0.025	0.0ThrXaa: 0.0 ± 0.0
Val	10.994ValAla: 10.994 ± 0.074	0.712ValCys: 0.712 ± 0.018	5.741ValAsp: 5.741 ± 0.049	5.357ValGlu: 5.357 ± 0.048	2.681ValPhe: 2.681 ± 0.033	6.488ValGly: 6.488 ± 0.055	2.106ValHis: 2.106 ± 0.031	3.407ValIle: 3.407 ± 0.043	2.176ValLys: 2.176 ± 0.033	10.513ValLeu: 10.513 ± 0.08	1.463ValMet: 1.463 ± 0.023	2.03ValAsn: 2.03 ± 0.036	5.093ValPro: 5.093 ± 0.043	2.566ValGln: 2.566 ± 0.029	6.861ValArg: 6.861 ± 0.067	5.132ValSer: 5.132 ± 0.039	5.796ValThr: 5.796 ± 0.056	9.46ValVal: 9.46 ± 0.076	1.224ValTrp: 1.224 ± 0.022	1.591ValTyr: 1.591 ± 0.028	0.0ValXaa: 0.0 ± 0.0
Trp	1.599TrpAla: 1.599 ± 0.024	0.141TrpCys: 0.141 ± 0.007	0.93TrpAsp: 0.93 ± 0.02	0.774TrpGlu: 0.774 ± 0.017	0.575TrpPhe: 0.575 ± 0.016	1.1TrpGly: 1.1 ± 0.022	0.412TrpHis: 0.412 ± 0.014	0.591TrpIle: 0.591 ± 0.015	0.387TrpLys: 0.387 ± 0.011	1.865TrpLeu: 1.865 ± 0.033	0.35TrpMet: 0.35 ± 0.011	0.505TrpAsn: 0.505 ± 0.016	0.855TrpPro: 0.855 ± 0.02	0.727TrpGln: 0.727 ± 0.018	1.33TrpArg: 1.33 ± 0.023	1.056TrpSer: 1.056 ± 0.022	1.105TrpThr: 1.105 ± 0.025	1.155TrpVal: 1.155 ± 0.022	0.369TrpTrp: 0.369 ± 0.015	0.35TrpTyr: 0.35 ± 0.013	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.348TyrAla: 2.348 ± 0.033	0.184TyrCys: 0.184 ± 0.009	1.388TyrAsp: 1.388 ± 0.025	1.14TyrGlu: 1.14 ± 0.022	0.71TyrPhe: 0.71 ± 0.018	1.997TyrGly: 1.997 ± 0.035	0.414TyrHis: 0.414 ± 0.013	0.487TyrIle: 0.487 ± 0.015	0.446TyrLys: 0.446 ± 0.014	2.233TyrLeu: 2.233 ± 0.032	0.256TyrMet: 0.256 ± 0.01	0.512TyrAsn: 0.512 ± 0.015	1.047TyrPro: 1.047 ± 0.021	0.719TyrGln: 0.719 ± 0.02	1.738TyrArg: 1.738 ± 0.026	1.182TyrSer: 1.182 ± 0.024	1.194TyrThr: 1.194 ± 0.025	1.745TyrVal: 1.745 ± 0.027	0.383TyrTrp: 0.383 ± 0.012	0.508TyrTyr: 0.508 ± 0.013	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 8237 proteins (2596602 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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