Amino acid dipepetide frequency for Ailuropoda melanoleuca papillomavirus 4

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.155AlaAla: 5.155 ± 1.412
1.718AlaCys: 1.718 ± 0.957
1.718AlaAsp: 1.718 ± 0.644
4.296AlaGlu: 4.296 ± 1.803
5.584AlaPhe: 5.584 ± 0.952
2.577AlaGly: 2.577 ± 1.291
0.43AlaHis: 0.43 ± 0.511
3.866AlaIle: 3.866 ± 1.385
3.007AlaLys: 3.007 ± 1.939
3.866AlaLeu: 3.866 ± 1.674
0.0AlaMet: 0.0 ± 0.0
1.718AlaAsn: 1.718 ± 1.009
1.718AlaPro: 1.718 ± 0.78
1.289AlaGln: 1.289 ± 0.697
3.007AlaArg: 3.007 ± 1.73
2.577AlaSer: 2.577 ± 0.796
4.296AlaThr: 4.296 ± 1.576
3.866AlaVal: 3.866 ± 0.967
0.43AlaTrp: 0.43 ± 0.355
3.007AlaTyr: 3.007 ± 0.895
0.0AlaXaa: 0.0 ± 0.0
Cys
2.148CysAla: 2.148 ± 1.459
0.43CysCys: 0.43 ± 0.504
1.289CysAsp: 1.289 ± 0.891
0.0CysGlu: 0.0 ± 0.0
1.289CysPhe: 1.289 ± 0.704
0.43CysGly: 0.43 ± 0.343
1.289CysHis: 1.289 ± 1.13
0.859CysIle: 0.859 ± 0.549
3.436CysLys: 3.436 ± 1.195
1.718CysLeu: 1.718 ± 0.562
0.43CysMet: 0.43 ± 0.343
0.43CysAsn: 0.43 ± 0.343
1.718CysPro: 1.718 ± 0.652
0.859CysGln: 0.859 ± 0.686
1.289CysArg: 1.289 ± 0.764
2.148CysSer: 2.148 ± 1.361
1.289CysThr: 1.289 ± 0.679
0.859CysVal: 0.859 ± 0.774
0.43CysTrp: 0.43 ± 0.343
1.289CysTyr: 1.289 ± 1.333
0.0CysXaa: 0.0 ± 0.0
Asp
2.577AspAla: 2.577 ± 1.104
2.148AspCys: 2.148 ± 1.06
2.577AspAsp: 2.577 ± 0.576
4.725AspGlu: 4.725 ± 0.935
3.436AspPhe: 3.436 ± 1.055
3.007AspGly: 3.007 ± 1.026
1.289AspHis: 1.289 ± 0.585
4.296AspIle: 4.296 ± 1.514
4.296AspLys: 4.296 ± 1.248
5.155AspLeu: 5.155 ± 1.383
0.43AspMet: 0.43 ± 0.355
3.436AspAsn: 3.436 ± 0.712
2.577AspPro: 2.577 ± 1.35
3.866AspGln: 3.866 ± 1.045
0.43AspArg: 0.43 ± 0.355
3.436AspSer: 3.436 ± 1.264
1.718AspThr: 1.718 ± 1.371
3.866AspVal: 3.866 ± 1.443
2.577AspTrp: 2.577 ± 1.165
3.007AspTyr: 3.007 ± 0.725
0.0AspXaa: 0.0 ± 0.0
Glu
4.296GluAla: 4.296 ± 0.897
0.43GluCys: 0.43 ± 0.343
5.155GluAsp: 5.155 ± 1.603
6.873GluGlu: 6.873 ± 2.359
2.148GluPhe: 2.148 ± 0.996
2.577GluGly: 2.577 ± 0.49
2.577GluHis: 2.577 ± 1.005
3.436GluIle: 3.436 ± 0.818
3.866GluLys: 3.866 ± 1.512
4.725GluLeu: 4.725 ± 0.7
0.43GluMet: 0.43 ± 0.343
3.436GluAsn: 3.436 ± 1.0
2.577GluPro: 2.577 ± 1.046
4.296GluGln: 4.296 ± 1.662
3.866GluArg: 3.866 ± 1.505
6.443GluSer: 6.443 ± 1.571
4.296GluThr: 4.296 ± 0.966
4.296GluVal: 4.296 ± 1.422
0.0GluTrp: 0.0 ± 0.0
0.859GluTyr: 0.859 ± 0.463
0.0GluXaa: 0.0 ± 0.0
Phe
2.148PheAla: 2.148 ± 1.317
1.718PheCys: 1.718 ± 1.099
6.014PheAsp: 6.014 ± 0.618
3.007PheGlu: 3.007 ± 0.839
2.148PhePhe: 2.148 ± 0.494
5.155PheGly: 5.155 ± 0.753
0.0PheHis: 0.0 ± 0.0
2.148PheIle: 2.148 ± 0.798
3.866PheLys: 3.866 ± 1.687
6.873PheLeu: 6.873 ± 1.085
1.718PheMet: 1.718 ± 0.546
1.289PheAsn: 1.289 ± 0.675
2.148PhePro: 2.148 ± 0.746
0.43PheGln: 0.43 ± 0.355
1.718PheArg: 1.718 ± 0.772
2.148PheSer: 2.148 ± 0.798
2.577PheThr: 2.577 ± 0.629
1.289PheVal: 1.289 ± 0.833
1.289PheTrp: 1.289 ± 0.679
3.007PheTyr: 3.007 ± 1.314
0.0PheXaa: 0.0 ± 0.0
Gly
2.577GlyAla: 2.577 ± 0.878
2.148GlyCys: 2.148 ± 1.143
3.436GlyAsp: 3.436 ± 1.365
6.873GlyGlu: 6.873 ± 2.295
1.718GlyPhe: 1.718 ± 0.882
4.725GlyGly: 4.725 ± 2.773
0.859GlyHis: 0.859 ± 0.463
3.007GlyIle: 3.007 ± 0.547
5.155GlyLys: 5.155 ± 1.639
5.584GlyLeu: 5.584 ± 1.149
0.859GlyMet: 0.859 ± 0.768
1.289GlyAsn: 1.289 ± 0.405
1.718GlyPro: 1.718 ± 1.018
1.718GlyGln: 1.718 ± 0.644
2.577GlyArg: 2.577 ± 1.217
5.584GlySer: 5.584 ± 2.018
4.296GlyThr: 4.296 ± 1.693
6.014GlyVal: 6.014 ± 1.61
0.43GlyTrp: 0.43 ± 0.355
1.289GlyTyr: 1.289 ± 0.656
0.0GlyXaa: 0.0 ± 0.0
His
0.859HisAla: 0.859 ± 0.419
0.0HisCys: 0.0 ± 0.0
0.43HisAsp: 0.43 ± 0.369
0.43HisGlu: 0.43 ± 0.369
2.148HisPhe: 2.148 ± 1.433
0.859HisGly: 0.859 ± 0.594
1.718HisHis: 1.718 ± 1.068
0.43HisIle: 0.43 ± 0.369
1.289HisLys: 1.289 ± 0.666
3.007HisLeu: 3.007 ± 1.269
0.859HisMet: 0.859 ± 0.71
0.43HisAsn: 0.43 ± 0.369
2.148HisPro: 2.148 ± 0.927
0.43HisGln: 0.43 ± 0.471
1.718HisArg: 1.718 ± 1.251
2.148HisSer: 2.148 ± 0.917
1.718HisThr: 1.718 ± 0.562
0.859HisVal: 0.859 ± 0.419
0.859HisTrp: 0.859 ± 0.461
0.859HisTyr: 0.859 ± 0.737
0.0HisXaa: 0.0 ± 0.0
Ile
2.577IleAla: 2.577 ± 0.462
0.0IleCys: 0.0 ± 0.0
3.007IleAsp: 3.007 ± 0.84
3.436IleGlu: 3.436 ± 0.899
1.718IlePhe: 1.718 ± 0.78
4.725IleGly: 4.725 ± 1.679
2.148IleHis: 2.148 ± 0.45
2.577IleIle: 2.577 ± 1.389
2.577IleLys: 2.577 ± 1.048
4.296IleLeu: 4.296 ± 1.127
0.0IleMet: 0.0 ± 0.0
0.859IleAsn: 0.859 ± 0.39
3.007IlePro: 3.007 ± 1.72
2.148IleGln: 2.148 ± 0.904
1.289IleArg: 1.289 ± 1.02
5.155IleSer: 5.155 ± 1.633
3.436IleThr: 3.436 ± 0.693
3.007IleVal: 3.007 ± 0.995
0.43IleTrp: 0.43 ± 0.343
1.718IleTyr: 1.718 ± 0.645
0.0IleXaa: 0.0 ± 0.0
Lys
4.725LysAla: 4.725 ± 1.213
2.577LysCys: 2.577 ± 0.901
1.718LysAsp: 1.718 ± 0.588
4.725LysGlu: 4.725 ± 1.752
4.296LysPhe: 4.296 ± 1.274
2.577LysGly: 2.577 ± 1.198
2.148LysHis: 2.148 ± 1.023
3.866LysIle: 3.866 ± 1.177
6.014LysLys: 6.014 ± 1.176
4.296LysLeu: 4.296 ± 1.138
0.859LysMet: 0.859 ± 0.685
2.148LysAsn: 2.148 ± 1.125
1.718LysPro: 1.718 ± 0.588
2.577LysGln: 2.577 ± 1.063
5.155LysArg: 5.155 ± 1.36
4.296LysSer: 4.296 ± 0.851
3.866LysThr: 3.866 ± 1.061
4.296LysVal: 4.296 ± 1.609
0.859LysTrp: 0.859 ± 0.941
2.148LysTyr: 2.148 ± 0.392
0.0LysXaa: 0.0 ± 0.0
Leu
5.155LeuAla: 5.155 ± 1.138
3.436LeuCys: 3.436 ± 2.308
4.725LeuAsp: 4.725 ± 0.618
3.866LeuGlu: 3.866 ± 1.342
7.302LeuPhe: 7.302 ± 2.014
5.584LeuGly: 5.584 ± 1.652
1.718LeuHis: 1.718 ± 0.978
3.007LeuIle: 3.007 ± 1.188
6.443LeuLys: 6.443 ± 1.766
9.88LeuLeu: 9.88 ± 3.505
2.148LeuMet: 2.148 ± 1.135
6.014LeuAsn: 6.014 ± 0.79
4.296LeuPro: 4.296 ± 0.907
7.302LeuGln: 7.302 ± 1.055
5.584LeuArg: 5.584 ± 0.783
6.443LeuSer: 6.443 ± 2.968
5.155LeuThr: 5.155 ± 1.788
5.584LeuVal: 5.584 ± 1.323
1.289LeuTrp: 1.289 ± 1.13
2.148LeuTyr: 2.148 ± 0.827
0.0LeuXaa: 0.0 ± 0.0
Met
1.289MetAla: 1.289 ± 0.81
0.43MetCys: 0.43 ± 0.343
0.43MetAsp: 0.43 ± 0.355
0.859MetGlu: 0.859 ± 0.491
0.859MetPhe: 0.859 ± 0.419
0.859MetGly: 0.859 ± 0.686
0.43MetHis: 0.43 ± 0.343
0.859MetIle: 0.859 ± 0.631
0.0MetLys: 0.0 ± 0.0
2.577MetLeu: 2.577 ± 0.878
0.0MetMet: 0.0 ± 0.0
0.43MetAsn: 0.43 ± 0.355
0.43MetPro: 0.43 ± 0.582
0.859MetGln: 0.859 ± 0.39
1.289MetArg: 1.289 ± 0.405
1.718MetSer: 1.718 ± 0.99
0.43MetThr: 0.43 ± 0.343
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.289AsnAla: 1.289 ± 0.704
0.859AsnCys: 0.859 ± 0.549
2.577AsnAsp: 2.577 ± 0.688
2.148AsnGlu: 2.148 ± 0.677
3.007AsnPhe: 3.007 ± 0.955
3.436AsnGly: 3.436 ± 0.657
0.859AsnHis: 0.859 ± 0.774
2.148AsnIle: 2.148 ± 0.663
2.577AsnLys: 2.577 ± 1.019
1.718AsnLeu: 1.718 ± 1.024
0.0AsnMet: 0.0 ± 0.0
2.148AsnAsn: 2.148 ± 0.671
3.007AsnPro: 3.007 ± 1.089
2.148AsnGln: 2.148 ± 0.845
4.296AsnArg: 4.296 ± 1.132
3.866AsnSer: 3.866 ± 0.635
3.436AsnThr: 3.436 ± 1.003
1.718AsnVal: 1.718 ± 0.816
0.0AsnTrp: 0.0 ± 0.0
0.859AsnTyr: 0.859 ± 0.419
0.0AsnXaa: 0.0 ± 0.0
Pro
4.296ProAla: 4.296 ± 1.664
1.289ProCys: 1.289 ± 0.666
3.866ProAsp: 3.866 ± 1.619
3.007ProGlu: 3.007 ± 1.241
0.859ProPhe: 0.859 ± 0.419
2.577ProGly: 2.577 ± 0.916
1.289ProHis: 1.289 ± 0.585
2.148ProIle: 2.148 ± 1.022
4.296ProLys: 4.296 ± 1.331
7.732ProLeu: 7.732 ± 1.625
0.0ProMet: 0.0 ± 0.0
1.718ProAsn: 1.718 ± 0.583
6.873ProPro: 6.873 ± 1.385
0.859ProGln: 0.859 ± 0.463
3.436ProArg: 3.436 ± 1.279
4.725ProSer: 4.725 ± 1.401
3.007ProThr: 3.007 ± 1.071
2.148ProVal: 2.148 ± 1.843
0.0ProTrp: 0.0 ± 0.0
1.718ProTyr: 1.718 ± 1.062
0.0ProXaa: 0.0 ± 0.0
Gln
3.007GlnAla: 3.007 ± 1.33
0.43GlnCys: 0.43 ± 0.343
3.436GlnAsp: 3.436 ± 1.044
3.866GlnGlu: 3.866 ± 1.115
1.289GlnPhe: 1.289 ± 0.439
1.289GlnGly: 1.289 ± 0.403
0.859GlnHis: 0.859 ± 0.463
1.289GlnIle: 1.289 ± 0.405
2.577GlnLys: 2.577 ± 0.885
4.725GlnLeu: 4.725 ± 1.496
1.289GlnMet: 1.289 ± 0.659
1.289GlnAsn: 1.289 ± 1.065
1.718GlnPro: 1.718 ± 0.856
2.148GlnGln: 2.148 ± 0.494
3.436GlnArg: 3.436 ± 0.956
1.289GlnSer: 1.289 ± 0.774
2.577GlnThr: 2.577 ± 1.051
1.718GlnVal: 1.718 ± 1.048
0.859GlnTrp: 0.859 ± 0.491
1.718GlnTyr: 1.718 ± 0.652
0.0GlnXaa: 0.0 ± 0.0
Arg
3.007ArgAla: 3.007 ± 1.243
0.43ArgCys: 0.43 ± 0.504
1.289ArgAsp: 1.289 ± 1.141
3.436ArgGlu: 3.436 ± 1.407
3.436ArgPhe: 3.436 ± 0.999
7.302ArgGly: 7.302 ± 1.719
1.718ArgHis: 1.718 ± 0.644
0.43ArgIle: 0.43 ± 0.369
4.725ArgLys: 4.725 ± 1.281
8.591ArgLeu: 8.591 ± 3.167
0.859ArgMet: 0.859 ± 0.491
3.007ArgAsn: 3.007 ± 0.878
4.725ArgPro: 4.725 ± 2.117
0.859ArgGln: 0.859 ± 0.39
5.584ArgArg: 5.584 ± 2.456
4.725ArgSer: 4.725 ± 0.89
2.148ArgThr: 2.148 ± 0.928
3.436ArgVal: 3.436 ± 0.981
0.43ArgTrp: 0.43 ± 0.343
2.148ArgTyr: 2.148 ± 1.369
0.0ArgXaa: 0.0 ± 0.0
Ser
3.866SerAla: 3.866 ± 1.448
1.718SerCys: 1.718 ± 1.009
6.443SerAsp: 6.443 ± 2.269
4.725SerGlu: 4.725 ± 1.066
3.436SerPhe: 3.436 ± 1.519
4.725SerGly: 4.725 ± 1.856
1.289SerHis: 1.289 ± 0.898
4.725SerIle: 4.725 ± 2.004
3.866SerLys: 3.866 ± 0.998
7.732SerLeu: 7.732 ± 2.09
0.43SerMet: 0.43 ± 0.343
3.866SerAsn: 3.866 ± 0.961
5.155SerPro: 5.155 ± 1.194
2.148SerGln: 2.148 ± 0.392
3.866SerArg: 3.866 ± 1.008
6.014SerSer: 6.014 ± 1.678
6.014SerThr: 6.014 ± 1.834
3.866SerVal: 3.866 ± 1.456
0.859SerTrp: 0.859 ± 0.686
1.289SerTyr: 1.289 ± 0.697
0.0SerXaa: 0.0 ± 0.0
Thr
0.43ThrAla: 0.43 ± 0.369
1.718ThrCys: 1.718 ± 0.711
3.866ThrAsp: 3.866 ± 1.53
3.866ThrGlu: 3.866 ± 0.626
1.718ThrPhe: 1.718 ± 1.018
4.296ThrGly: 4.296 ± 1.208
0.859ThrHis: 0.859 ± 0.584
1.289ThrIle: 1.289 ± 0.403
2.148ThrLys: 2.148 ± 0.677
6.443ThrLeu: 6.443 ± 1.632
2.148ThrMet: 2.148 ± 0.979
3.866ThrAsn: 3.866 ± 1.392
4.296ThrPro: 4.296 ± 1.267
1.718ThrGln: 1.718 ± 0.592
6.014ThrArg: 6.014 ± 1.897
6.443ThrSer: 6.443 ± 1.629
3.436ThrThr: 3.436 ± 1.182
3.866ThrVal: 3.866 ± 1.063
0.859ThrTrp: 0.859 ± 0.461
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
1.718ValAla: 1.718 ± 0.672
0.859ValCys: 0.859 ± 0.631
5.155ValAsp: 5.155 ± 1.057
3.436ValGlu: 3.436 ± 1.298
2.577ValPhe: 2.577 ± 0.807
2.577ValGly: 2.577 ± 1.048
0.0ValHis: 0.0 ± 0.0
4.296ValIle: 4.296 ± 2.316
3.007ValLys: 3.007 ± 0.957
4.296ValLeu: 4.296 ± 1.119
0.859ValMet: 0.859 ± 0.408
3.007ValAsn: 3.007 ± 0.73
3.866ValPro: 3.866 ± 1.062
2.577ValGln: 2.577 ± 1.152
5.155ValArg: 5.155 ± 0.725
6.014ValSer: 6.014 ± 1.18
2.577ValThr: 2.577 ± 1.058
1.718ValVal: 1.718 ± 0.588
0.859ValTrp: 0.859 ± 0.71
0.859ValTyr: 0.859 ± 0.524
0.0ValXaa: 0.0 ± 0.0
Trp
0.859TrpAla: 0.859 ± 0.686
0.43TrpCys: 0.43 ± 0.355
0.859TrpAsp: 0.859 ± 0.491
0.43TrpGlu: 0.43 ± 0.355
0.0TrpPhe: 0.0 ± 0.0
0.859TrpGly: 0.859 ± 0.419
0.859TrpHis: 0.859 ± 0.461
1.718TrpIle: 1.718 ± 0.592
1.289TrpLys: 1.289 ± 1.029
0.859TrpLeu: 0.859 ± 0.419
0.0TrpMet: 0.0 ± 0.0
0.43TrpAsn: 0.43 ± 0.355
0.0TrpPro: 0.0 ± 0.0
1.289TrpGln: 1.289 ± 0.925
0.43TrpArg: 0.43 ± 0.504
0.0TrpSer: 0.0 ± 0.0
1.718TrpThr: 1.718 ± 0.991
0.859TrpVal: 0.859 ± 0.686
0.0TrpTrp: 0.0 ± 0.0
0.43TrpTyr: 0.43 ± 0.343
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.148TyrAla: 2.148 ± 0.677
0.859TyrCys: 0.859 ± 0.491
0.859TyrAsp: 0.859 ± 0.39
2.577TyrGlu: 2.577 ± 0.987
1.718TyrPhe: 1.718 ± 0.588
1.718TyrGly: 1.718 ± 0.816
0.859TyrHis: 0.859 ± 0.622
1.718TyrIle: 1.718 ± 0.838
0.859TyrLys: 0.859 ± 0.574
3.007TyrLeu: 3.007 ± 0.892
0.0TyrMet: 0.0 ± 0.0
1.289TyrAsn: 1.289 ± 0.677
2.148TyrPro: 2.148 ± 1.141
1.289TyrGln: 1.289 ± 0.704
2.148TyrArg: 2.148 ± 0.783
0.859TyrSer: 0.859 ± 0.737
1.289TyrThr: 1.289 ± 0.439
2.148TyrVal: 2.148 ± 0.646
0.859TyrTrp: 0.859 ± 0.419
3.866TyrTyr: 3.866 ± 1.189
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (2329 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski