Amino acid dipepetide frequency for Acidianus rod-shaped virus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
0.0AlaAla: 0.0 ± 0.0
0.437AlaCys: 0.437 ± 0.244
3.933AlaAsp: 3.933 ± 0.49
4.516AlaGlu: 4.516 ± 0.811
2.768AlaPhe: 2.768 ± 0.772
2.622AlaGly: 2.622 ± 0.555
0.146AlaHis: 0.146 ± 0.147
7.575AlaIle: 7.575 ± 1.108
5.244AlaLys: 5.244 ± 0.889
5.972AlaLeu: 5.972 ± 1.232
1.602AlaMet: 1.602 ± 0.416
3.205AlaAsn: 3.205 ± 0.734
1.748AlaPro: 1.748 ± 0.496
2.476AlaGln: 2.476 ± 0.72
2.185AlaArg: 2.185 ± 0.399
3.205AlaSer: 3.205 ± 0.65
3.059AlaThr: 3.059 ± 0.638
3.933AlaVal: 3.933 ± 0.602
1.02AlaTrp: 1.02 ± 0.256
3.496AlaTyr: 3.496 ± 0.948
0.0AlaXaa: 0.0 ± 0.0
Cys
0.291CysAla: 0.291 ± 0.175
0.0CysCys: 0.0 ± 0.0
0.874CysAsp: 0.874 ± 0.355
0.874CysGlu: 0.874 ± 0.527
0.146CysPhe: 0.146 ± 0.147
0.728CysGly: 0.728 ± 0.377
0.291CysHis: 0.291 ± 0.211
0.728CysIle: 0.728 ± 0.325
0.728CysLys: 0.728 ± 0.372
0.583CysLeu: 0.583 ± 0.239
0.0CysMet: 0.0 ± 0.0
1.311CysAsn: 1.311 ± 0.623
0.146CysPro: 0.146 ± 0.152
0.437CysGln: 0.437 ± 0.211
0.0CysArg: 0.0 ± 0.0
0.291CysSer: 0.291 ± 0.203
0.291CysThr: 0.291 ± 0.175
0.146CysVal: 0.146 ± 0.182
0.0CysTrp: 0.0 ± 0.0
0.583CysTyr: 0.583 ± 0.341
0.0CysXaa: 0.0 ± 0.0
Asp
4.224AspAla: 4.224 ± 0.611
0.583AspCys: 0.583 ± 0.346
2.331AspAsp: 2.331 ± 0.626
5.972AspGlu: 5.972 ± 1.225
2.476AspPhe: 2.476 ± 0.539
1.311AspGly: 1.311 ± 0.401
0.728AspHis: 0.728 ± 0.28
6.846AspIle: 6.846 ± 1.212
3.205AspLys: 3.205 ± 0.939
6.555AspLeu: 6.555 ± 1.143
0.728AspMet: 0.728 ± 0.326
3.059AspAsn: 3.059 ± 0.752
1.02AspPro: 1.02 ± 0.335
2.331AspGln: 2.331 ± 0.458
2.185AspArg: 2.185 ± 0.566
1.748AspSer: 1.748 ± 0.349
1.02AspThr: 1.02 ± 0.385
2.768AspVal: 2.768 ± 0.693
0.583AspTrp: 0.583 ± 0.332
2.622AspTyr: 2.622 ± 0.534
0.0AspXaa: 0.0 ± 0.0
Glu
2.476GluAla: 2.476 ± 0.404
0.437GluCys: 0.437 ± 0.26
2.476GluAsp: 2.476 ± 0.847
3.933GluGlu: 3.933 ± 0.75
2.622GluPhe: 2.622 ± 0.526
2.039GluGly: 2.039 ± 0.552
0.874GluHis: 0.874 ± 0.391
9.905GluIle: 9.905 ± 1.948
7.429GluLys: 7.429 ± 1.152
5.681GluLeu: 5.681 ± 1.256
1.748GluMet: 1.748 ± 0.468
5.098GluAsn: 5.098 ± 0.847
1.165GluPro: 1.165 ± 0.527
2.913GluGln: 2.913 ± 0.666
1.602GluArg: 1.602 ± 0.478
2.039GluSer: 2.039 ± 0.456
3.642GluThr: 3.642 ± 0.815
3.205GluVal: 3.205 ± 0.723
0.583GluTrp: 0.583 ± 0.318
4.224GluTyr: 4.224 ± 0.787
0.0GluXaa: 0.0 ± 0.0
Phe
4.079PheAla: 4.079 ± 0.491
1.02PheCys: 1.02 ± 0.532
3.059PheAsp: 3.059 ± 0.556
3.059PheGlu: 3.059 ± 0.409
2.768PhePhe: 2.768 ± 0.836
3.059PheGly: 3.059 ± 0.689
0.437PheHis: 0.437 ± 0.205
3.35PheIle: 3.35 ± 0.621
3.496PheLys: 3.496 ± 0.619
4.953PheLeu: 4.953 ± 0.872
0.874PheMet: 0.874 ± 0.371
2.913PheAsn: 2.913 ± 0.606
2.185PhePro: 2.185 ± 0.691
2.622PheGln: 2.622 ± 0.47
1.311PheArg: 1.311 ± 0.438
3.787PheSer: 3.787 ± 0.68
3.642PheThr: 3.642 ± 0.66
4.516PheVal: 4.516 ± 0.933
0.0PheTrp: 0.0 ± 0.0
1.894PheTyr: 1.894 ± 0.477
0.0PheXaa: 0.0 ± 0.0
Gly
3.205GlyAla: 3.205 ± 0.47
0.437GlyCys: 0.437 ± 0.267
2.913GlyAsp: 2.913 ± 0.419
2.331GlyGlu: 2.331 ± 0.437
2.913GlyPhe: 2.913 ± 0.767
2.331GlyGly: 2.331 ± 0.798
0.291GlyHis: 0.291 ± 0.243
3.642GlyIle: 3.642 ± 0.8
2.622GlyLys: 2.622 ± 0.591
3.933GlyLeu: 3.933 ± 0.807
0.728GlyMet: 0.728 ± 0.233
2.039GlyAsn: 2.039 ± 0.491
1.748GlyPro: 1.748 ± 0.536
1.02GlyGln: 1.02 ± 0.374
0.583GlyArg: 0.583 ± 0.447
3.35GlySer: 3.35 ± 0.813
2.039GlyThr: 2.039 ± 0.516
4.224GlyVal: 4.224 ± 0.872
0.146GlyTrp: 0.146 ± 0.13
3.205GlyTyr: 3.205 ± 0.649
0.0GlyXaa: 0.0 ± 0.0
His
0.583HisAla: 0.583 ± 0.262
0.291HisCys: 0.291 ± 0.216
0.728HisAsp: 0.728 ± 0.302
0.874HisGlu: 0.874 ± 0.471
1.02HisPhe: 1.02 ± 0.387
1.02HisGly: 1.02 ± 0.465
0.291HisHis: 0.291 ± 0.178
1.02HisIle: 1.02 ± 0.532
1.02HisLys: 1.02 ± 0.39
1.165HisLeu: 1.165 ± 0.347
1.02HisMet: 1.02 ± 0.49
0.291HisAsn: 0.291 ± 0.231
0.437HisPro: 0.437 ± 0.269
0.437HisGln: 0.437 ± 0.313
0.437HisArg: 0.437 ± 0.257
0.874HisSer: 0.874 ± 0.493
0.728HisThr: 0.728 ± 0.294
1.02HisVal: 1.02 ± 0.332
0.146HisTrp: 0.146 ± 0.136
0.583HisTyr: 0.583 ± 0.32
0.0HisXaa: 0.0 ± 0.0
Ile
6.118IleAla: 6.118 ± 0.829
1.02IleCys: 1.02 ± 0.439
3.642IleAsp: 3.642 ± 0.691
7.429IleGlu: 7.429 ± 1.214
5.244IlePhe: 5.244 ± 0.856
2.768IleGly: 2.768 ± 0.636
1.748IleHis: 1.748 ± 0.579
7.72IleIle: 7.72 ± 1.386
6.118IleLys: 6.118 ± 1.17
6.846IleLeu: 6.846 ± 0.871
1.02IleMet: 1.02 ± 0.333
3.933IleAsn: 3.933 ± 0.826
4.661IlePro: 4.661 ± 0.799
5.535IleGln: 5.535 ± 0.741
2.913IleArg: 2.913 ± 0.851
8.012IleSer: 8.012 ± 1.38
4.661IleThr: 4.661 ± 1.083
5.827IleVal: 5.827 ± 1.199
0.728IleTrp: 0.728 ± 0.232
5.244IleTyr: 5.244 ± 1.288
0.0IleXaa: 0.0 ± 0.0
Lys
4.516LysAla: 4.516 ± 0.938
0.146LysCys: 0.146 ± 0.152
3.059LysAsp: 3.059 ± 0.779
5.098LysGlu: 5.098 ± 1.252
3.35LysPhe: 3.35 ± 0.687
2.185LysGly: 2.185 ± 0.436
1.02LysHis: 1.02 ± 0.553
9.323LysIle: 9.323 ± 1.613
7.72LysLys: 7.72 ± 1.291
8.449LysLeu: 8.449 ± 1.209
2.185LysMet: 2.185 ± 0.569
4.37LysAsn: 4.37 ± 0.902
2.039LysPro: 2.039 ± 0.607
2.913LysGln: 2.913 ± 1.053
1.602LysArg: 1.602 ± 0.48
2.768LysSer: 2.768 ± 0.638
4.516LysThr: 4.516 ± 0.768
4.224LysVal: 4.224 ± 0.845
0.437LysTrp: 0.437 ± 0.266
5.827LysTyr: 5.827 ± 0.849
0.0LysXaa: 0.0 ± 0.0
Leu
3.787LeuAla: 3.787 ± 0.676
1.02LeuCys: 1.02 ± 0.468
5.681LeuAsp: 5.681 ± 0.79
4.079LeuGlu: 4.079 ± 0.849
4.516LeuPhe: 4.516 ± 0.894
4.224LeuGly: 4.224 ± 0.989
1.02LeuHis: 1.02 ± 0.475
4.953LeuIle: 4.953 ± 1.591
9.323LeuLys: 9.323 ± 1.404
9.323LeuLeu: 9.323 ± 1.568
2.039LeuMet: 2.039 ± 0.517
4.953LeuAsn: 4.953 ± 0.871
4.661LeuPro: 4.661 ± 0.767
6.264LeuGln: 6.264 ± 1.22
3.35LeuArg: 3.35 ± 0.981
6.264LeuSer: 6.264 ± 1.011
5.098LeuThr: 5.098 ± 1.117
3.35LeuVal: 3.35 ± 0.603
0.437LeuTrp: 0.437 ± 0.261
6.409LeuTyr: 6.409 ± 0.936
0.0LeuXaa: 0.0 ± 0.0
Met
1.602MetAla: 1.602 ± 0.533
0.0MetCys: 0.0 ± 0.0
1.165MetAsp: 1.165 ± 0.623
1.457MetGlu: 1.457 ± 0.571
1.02MetPhe: 1.02 ± 0.514
0.728MetGly: 0.728 ± 0.336
0.437MetHis: 0.437 ± 0.241
0.874MetIle: 0.874 ± 0.366
1.165MetLys: 1.165 ± 0.438
1.311MetLeu: 1.311 ± 0.355
0.291MetMet: 0.291 ± 0.151
1.02MetAsn: 1.02 ± 0.44
1.02MetPro: 1.02 ± 0.361
1.165MetGln: 1.165 ± 0.405
1.165MetArg: 1.165 ± 0.339
1.748MetSer: 1.748 ± 0.525
0.583MetThr: 0.583 ± 0.276
0.874MetVal: 0.874 ± 0.4
0.146MetTrp: 0.146 ± 0.127
1.311MetTyr: 1.311 ± 0.371
0.0MetXaa: 0.0 ± 0.0
Asn
3.642AsnAla: 3.642 ± 0.588
1.02AsnCys: 1.02 ± 0.393
2.768AsnAsp: 2.768 ± 0.712
4.37AsnGlu: 4.37 ± 0.928
5.244AsnPhe: 5.244 ± 0.809
1.894AsnGly: 1.894 ± 0.531
1.02AsnHis: 1.02 ± 0.394
6.701AsnIle: 6.701 ± 1.066
2.913AsnLys: 2.913 ± 0.875
4.807AsnLeu: 4.807 ± 1.074
0.874AsnMet: 0.874 ± 0.356
4.224AsnAsn: 4.224 ± 1.293
2.476AsnPro: 2.476 ± 0.682
3.059AsnGln: 3.059 ± 0.731
1.602AsnArg: 1.602 ± 0.416
5.972AsnSer: 5.972 ± 1.399
2.622AsnThr: 2.622 ± 1.098
5.827AsnVal: 5.827 ± 0.709
0.583AsnTrp: 0.583 ± 0.204
4.079AsnTyr: 4.079 ± 0.923
0.0AsnXaa: 0.0 ± 0.0
Pro
2.622ProAla: 2.622 ± 0.475
0.146ProCys: 0.146 ± 0.127
2.185ProAsp: 2.185 ± 0.496
2.039ProGlu: 2.039 ± 0.508
1.748ProPhe: 1.748 ± 0.396
1.457ProGly: 1.457 ± 0.324
0.583ProHis: 0.583 ± 0.314
2.622ProIle: 2.622 ± 0.565
2.476ProLys: 2.476 ± 0.611
2.185ProLeu: 2.185 ± 0.407
0.437ProMet: 0.437 ± 0.26
2.622ProAsn: 2.622 ± 0.54
2.185ProPro: 2.185 ± 0.42
1.02ProGln: 1.02 ± 0.354
1.311ProArg: 1.311 ± 0.418
3.787ProSer: 3.787 ± 1.02
2.476ProThr: 2.476 ± 0.62
3.059ProVal: 3.059 ± 0.461
0.146ProTrp: 0.146 ± 0.119
2.476ProTyr: 2.476 ± 0.546
0.0ProXaa: 0.0 ± 0.0
Gln
1.457GlnAla: 1.457 ± 0.407
0.437GlnCys: 0.437 ± 0.234
2.331GlnAsp: 2.331 ± 0.612
2.913GlnGlu: 2.913 ± 0.736
1.748GlnPhe: 1.748 ± 0.368
2.331GlnGly: 2.331 ± 0.439
0.874GlnHis: 0.874 ± 0.319
4.807GlnIle: 4.807 ± 0.844
4.516GlnLys: 4.516 ± 0.722
5.535GlnLeu: 5.535 ± 1.209
0.583GlnMet: 0.583 ± 0.281
5.972GlnAsn: 5.972 ± 1.195
1.02GlnPro: 1.02 ± 0.389
3.205GlnGln: 3.205 ± 0.742
1.165GlnArg: 1.165 ± 0.33
1.602GlnSer: 1.602 ± 0.366
2.331GlnThr: 2.331 ± 0.5
2.768GlnVal: 2.768 ± 0.776
0.291GlnTrp: 0.291 ± 0.166
3.787GlnTyr: 3.787 ± 0.738
0.0GlnXaa: 0.0 ± 0.0
Arg
1.602ArgAla: 1.602 ± 0.394
0.146ArgCys: 0.146 ± 0.152
1.311ArgAsp: 1.311 ± 0.412
1.748ArgGlu: 1.748 ± 0.623
2.331ArgPhe: 2.331 ± 0.779
1.165ArgGly: 1.165 ± 0.396
0.874ArgHis: 0.874 ± 0.253
2.476ArgIle: 2.476 ± 0.602
2.331ArgLys: 2.331 ± 0.628
2.331ArgLeu: 2.331 ± 0.564
0.583ArgMet: 0.583 ± 0.411
1.602ArgAsn: 1.602 ± 0.593
0.291ArgPro: 0.291 ± 0.181
1.748ArgGln: 1.748 ± 0.622
1.457ArgArg: 1.457 ± 0.452
2.039ArgSer: 2.039 ± 0.497
1.02ArgThr: 1.02 ± 0.336
1.748ArgVal: 1.748 ± 0.505
0.146ArgTrp: 0.146 ± 0.182
1.165ArgTyr: 1.165 ± 0.375
0.0ArgXaa: 0.0 ± 0.0
Ser
4.953SerAla: 4.953 ± 0.831
0.146SerCys: 0.146 ± 0.127
4.224SerAsp: 4.224 ± 1.009
2.476SerGlu: 2.476 ± 0.481
3.059SerPhe: 3.059 ± 0.577
5.681SerGly: 5.681 ± 1.076
1.602SerHis: 1.602 ± 0.506
3.496SerIle: 3.496 ± 0.529
4.079SerLys: 4.079 ± 0.828
3.933SerLeu: 3.933 ± 0.939
1.02SerMet: 1.02 ± 0.392
5.098SerAsn: 5.098 ± 0.945
2.476SerPro: 2.476 ± 0.868
3.933SerGln: 3.933 ± 0.818
1.894SerArg: 1.894 ± 0.623
3.787SerSer: 3.787 ± 1.359
4.516SerThr: 4.516 ± 1.062
3.35SerVal: 3.35 ± 0.701
1.02SerTrp: 1.02 ± 0.25
3.059SerTyr: 3.059 ± 0.641
0.0SerXaa: 0.0 ± 0.0
Thr
4.661ThrAla: 4.661 ± 1.086
0.291ThrCys: 0.291 ± 0.211
2.476ThrAsp: 2.476 ± 0.67
3.35ThrGlu: 3.35 ± 0.795
1.894ThrPhe: 1.894 ± 0.459
3.059ThrGly: 3.059 ± 0.604
0.437ThrHis: 0.437 ± 0.196
5.681ThrIle: 5.681 ± 1.113
2.476ThrLys: 2.476 ± 0.474
4.224ThrLeu: 4.224 ± 0.918
1.165ThrMet: 1.165 ± 0.342
3.496ThrAsn: 3.496 ± 0.802
2.768ThrPro: 2.768 ± 0.673
2.185ThrGln: 2.185 ± 0.535
0.874ThrArg: 0.874 ± 0.33
3.059ThrSer: 3.059 ± 0.727
3.059ThrThr: 3.059 ± 0.525
3.496ThrVal: 3.496 ± 0.65
0.437ThrTrp: 0.437 ± 0.211
3.35ThrTyr: 3.35 ± 0.74
0.0ThrXaa: 0.0 ± 0.0
Val
5.244ValAla: 5.244 ± 0.826
0.437ValCys: 0.437 ± 0.235
3.642ValAsp: 3.642 ± 0.748
5.244ValGlu: 5.244 ± 0.91
3.787ValPhe: 3.787 ± 0.607
1.602ValGly: 1.602 ± 0.513
0.728ValHis: 0.728 ± 0.338
3.787ValIle: 3.787 ± 0.657
4.079ValLys: 4.079 ± 1.041
5.681ValLeu: 5.681 ± 0.791
1.02ValMet: 1.02 ± 0.363
4.224ValAsn: 4.224 ± 0.491
3.205ValPro: 3.205 ± 0.87
2.331ValGln: 2.331 ± 0.58
0.728ValArg: 0.728 ± 0.464
5.827ValSer: 5.827 ± 0.895
3.059ValThr: 3.059 ± 0.796
2.768ValVal: 2.768 ± 0.472
0.291ValTrp: 0.291 ± 0.192
4.224ValTyr: 4.224 ± 1.065
0.0ValXaa: 0.0 ± 0.0
Trp
0.583TrpAla: 0.583 ± 0.276
0.146TrpCys: 0.146 ± 0.13
0.291TrpAsp: 0.291 ± 0.188
0.146TrpGlu: 0.146 ± 0.127
0.437TrpPhe: 0.437 ± 0.196
0.0TrpGly: 0.0 ± 0.0
0.146TrpHis: 0.146 ± 0.119
0.437TrpIle: 0.437 ± 0.18
1.457TrpLys: 1.457 ± 0.526
0.146TrpLeu: 0.146 ± 0.138
0.0TrpMet: 0.0 ± 0.0
1.311TrpAsn: 1.311 ± 0.399
0.0TrpPro: 0.0 ± 0.0
0.583TrpGln: 0.583 ± 0.23
0.291TrpArg: 0.291 ± 0.171
0.437TrpSer: 0.437 ± 0.295
0.728TrpThr: 0.728 ± 0.272
0.146TrpVal: 0.146 ± 0.13
0.0TrpTrp: 0.0 ± 0.0
0.291TrpTyr: 0.291 ± 0.178
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.496TyrAla: 3.496 ± 0.781
0.291TyrCys: 0.291 ± 0.222
3.205TyrAsp: 3.205 ± 0.684
2.185TyrGlu: 2.185 ± 0.494
4.079TyrPhe: 4.079 ± 0.87
3.496TyrGly: 3.496 ± 0.527
0.437TyrHis: 0.437 ± 0.218
5.244TyrIle: 5.244 ± 0.645
3.35TyrLys: 3.35 ± 0.568
7.138TyrLeu: 7.138 ± 0.978
1.02TyrMet: 1.02 ± 0.321
4.953TyrAsn: 4.953 ± 1.066
2.331TyrPro: 2.331 ± 0.555
3.496TyrGln: 3.496 ± 0.628
1.457TyrArg: 1.457 ± 0.506
3.205TyrSer: 3.205 ± 0.676
3.35TyrThr: 3.35 ± 0.63
4.661TyrVal: 4.661 ± 0.805
0.437TyrTrp: 0.437 ± 0.224
3.933TyrTyr: 3.933 ± 0.808
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 33 proteins (6866 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski