Amino acid dipepetide frequency for Canis familiaris papillomavirus 6

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.974AlaAla: 2.974 ± 0.526
0.425AlaCys: 0.425 ± 0.338
4.248AlaAsp: 4.248 ± 0.913
4.248AlaGlu: 4.248 ± 1.585
2.549AlaPhe: 2.549 ± 0.664
2.124AlaGly: 2.124 ± 0.485
0.425AlaHis: 0.425 ± 0.399
3.823AlaIle: 3.823 ± 1.19
4.248AlaLys: 4.248 ± 2.169
5.098AlaLeu: 5.098 ± 0.982
0.425AlaMet: 0.425 ± 0.399
2.124AlaAsn: 2.124 ± 1.549
2.549AlaPro: 2.549 ± 1.584
2.124AlaGln: 2.124 ± 0.867
2.549AlaArg: 2.549 ± 1.365
5.523AlaSer: 5.523 ± 0.871
3.823AlaThr: 3.823 ± 1.61
2.124AlaVal: 2.124 ± 0.493
0.425AlaTrp: 0.425 ± 0.399
1.274AlaTyr: 1.274 ± 0.623
0.0AlaXaa: 0.0 ± 0.0
Cys
0.85CysAla: 0.85 ± 0.618
0.425CysCys: 0.425 ± 0.556
0.425CysAsp: 0.425 ± 0.556
0.425CysGlu: 0.425 ± 0.338
1.274CysPhe: 1.274 ± 0.462
1.274CysGly: 1.274 ± 1.022
0.425CysHis: 0.425 ± 0.556
0.85CysIle: 0.85 ± 0.678
2.974CysLys: 2.974 ± 0.918
2.124CysLeu: 2.124 ± 1.313
0.85CysMet: 0.85 ± 0.618
0.425CysAsn: 0.425 ± 0.556
1.699CysPro: 1.699 ± 0.655
0.85CysGln: 0.85 ± 0.618
0.85CysArg: 0.85 ± 0.618
1.274CysSer: 1.274 ± 0.826
0.0CysThr: 0.0 ± 0.0
1.699CysVal: 1.699 ± 0.763
0.425CysTrp: 0.425 ± 0.338
0.425CysTyr: 0.425 ± 0.512
0.0CysXaa: 0.0 ± 0.0
Asp
2.549AspAla: 2.549 ± 0.609
2.124AspCys: 2.124 ± 1.42
5.098AspAsp: 5.098 ± 2.115
4.673AspGlu: 4.673 ± 1.232
3.398AspPhe: 3.398 ± 1.273
2.974AspGly: 2.974 ± 0.996
0.85AspHis: 0.85 ± 0.488
6.797AspIle: 6.797 ± 2.209
3.823AspLys: 3.823 ± 1.421
8.496AspLeu: 8.496 ± 2.845
0.425AspMet: 0.425 ± 0.399
2.974AspAsn: 2.974 ± 0.647
4.248AspPro: 4.248 ± 1.903
2.549AspGln: 2.549 ± 0.937
2.549AspArg: 2.549 ± 1.484
4.673AspSer: 4.673 ± 1.127
3.398AspThr: 3.398 ± 1.03
2.549AspVal: 2.549 ± 0.473
0.85AspTrp: 0.85 ± 0.676
2.124AspTyr: 2.124 ± 1.1
0.0AspXaa: 0.0 ± 0.0
Glu
3.823GluAla: 3.823 ± 1.239
0.425GluCys: 0.425 ± 0.338
4.248GluAsp: 4.248 ± 1.774
8.071GluGlu: 8.071 ± 3.172
1.274GluPhe: 1.274 ± 0.376
4.673GluGly: 4.673 ± 0.503
1.274GluHis: 1.274 ± 0.662
3.398GluIle: 3.398 ± 0.599
4.673GluLys: 4.673 ± 2.414
4.248GluLeu: 4.248 ± 1.149
0.425GluMet: 0.425 ± 0.338
3.823GluAsn: 3.823 ± 1.19
1.274GluPro: 1.274 ± 1.022
5.947GluGln: 5.947 ± 1.163
5.523GluArg: 5.523 ± 1.215
6.372GluSer: 6.372 ± 2.095
3.398GluThr: 3.398 ± 1.081
2.549GluVal: 2.549 ± 1.062
0.425GluTrp: 0.425 ± 0.338
1.274GluTyr: 1.274 ± 0.623
0.0GluXaa: 0.0 ± 0.0
Phe
2.974PheAla: 2.974 ± 1.15
1.699PheCys: 1.699 ± 1.101
6.372PheAsp: 6.372 ± 0.821
3.398PheGlu: 3.398 ± 1.681
1.274PhePhe: 1.274 ± 0.58
2.124PheGly: 2.124 ± 0.557
0.425PheHis: 0.425 ± 0.399
1.274PheIle: 1.274 ± 0.623
2.974PheLys: 2.974 ± 1.617
5.947PheLeu: 5.947 ± 1.38
1.274PheMet: 1.274 ± 0.745
1.699PheAsn: 1.699 ± 0.501
2.124PhePro: 2.124 ± 1.665
2.974PheGln: 2.974 ± 1.087
1.699PheArg: 1.699 ± 0.27
1.274PheSer: 1.274 ± 0.941
2.124PheThr: 2.124 ± 1.018
1.699PheVal: 1.699 ± 1.127
2.124PheTrp: 2.124 ± 1.237
2.549PheTyr: 2.549 ± 1.237
0.0PheXaa: 0.0 ± 0.0
Gly
2.549GlyAla: 2.549 ± 1.071
0.85GlyCys: 0.85 ± 0.615
3.398GlyAsp: 3.398 ± 0.9
5.523GlyGlu: 5.523 ± 1.095
1.699GlyPhe: 1.699 ± 0.624
3.823GlyGly: 3.823 ± 2.196
1.274GlyHis: 1.274 ± 0.473
1.699GlyIle: 1.699 ± 0.655
1.699GlyLys: 1.699 ± 0.766
5.523GlyLeu: 5.523 ± 1.312
1.274GlyMet: 1.274 ± 0.818
2.549GlyAsn: 2.549 ± 0.523
2.974GlyPro: 2.974 ± 1.104
3.823GlyGln: 3.823 ± 0.94
2.549GlyArg: 2.549 ± 1.159
4.673GlySer: 4.673 ± 0.966
5.098GlyThr: 5.098 ± 1.879
4.248GlyVal: 4.248 ± 1.578
0.425GlyTrp: 0.425 ± 0.399
0.425GlyTyr: 0.425 ± 0.394
0.0GlyXaa: 0.0 ± 0.0
His
0.425HisAla: 0.425 ± 0.399
0.425HisCys: 0.425 ± 0.512
0.85HisAsp: 0.85 ± 0.623
0.85HisGlu: 0.85 ± 0.4
1.274HisPhe: 1.274 ± 1.002
0.425HisGly: 0.425 ± 0.512
0.85HisHis: 0.85 ± 0.469
0.425HisIle: 0.425 ± 0.394
0.425HisLys: 0.425 ± 0.338
1.699HisLeu: 1.699 ± 0.792
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
1.274HisPro: 1.274 ± 0.792
0.85HisGln: 0.85 ± 0.676
0.425HisArg: 0.425 ± 0.556
0.85HisSer: 0.85 ± 0.439
0.85HisThr: 0.85 ± 0.517
1.274HisVal: 1.274 ± 0.376
1.274HisTrp: 1.274 ± 0.462
0.85HisTyr: 0.85 ± 0.789
0.0HisXaa: 0.0 ± 0.0
Ile
3.823IleAla: 3.823 ± 0.786
0.0IleCys: 0.0 ± 0.0
2.124IleAsp: 2.124 ± 0.681
5.098IleGlu: 5.098 ± 1.005
1.274IlePhe: 1.274 ± 0.8
5.098IleGly: 5.098 ± 1.44
0.425IleHis: 0.425 ± 0.399
3.398IleIle: 3.398 ± 1.286
2.549IleLys: 2.549 ± 1.084
2.549IleLeu: 2.549 ± 1.062
0.0IleMet: 0.0 ± 0.0
0.425IleAsn: 0.425 ± 0.399
2.974IlePro: 2.974 ± 1.961
1.699IleGln: 1.699 ± 1.166
2.974IleArg: 2.974 ± 1.482
6.797IleSer: 6.797 ± 2.975
1.699IleThr: 1.699 ± 1.152
2.124IleVal: 2.124 ± 0.679
0.0IleTrp: 0.0 ± 0.0
2.549IleTyr: 2.549 ± 0.886
0.0IleXaa: 0.0 ± 0.0
Lys
3.823LysAla: 3.823 ± 1.038
1.699LysCys: 1.699 ± 0.618
2.124LysAsp: 2.124 ± 0.841
2.974LysGlu: 2.974 ± 1.191
3.823LysPhe: 3.823 ± 1.308
2.974LysGly: 2.974 ± 1.038
0.85LysHis: 0.85 ± 0.676
2.124LysIle: 2.124 ± 1.155
5.947LysLys: 5.947 ± 1.518
3.823LysLeu: 3.823 ± 1.322
0.85LysMet: 0.85 ± 0.651
4.248LysAsn: 4.248 ± 1.558
1.699LysPro: 1.699 ± 0.523
2.974LysGln: 2.974 ± 1.0
3.398LysArg: 3.398 ± 1.023
5.523LysSer: 5.523 ± 2.109
2.549LysThr: 2.549 ± 0.956
3.398LysVal: 3.398 ± 1.258
0.0LysTrp: 0.0 ± 0.0
3.398LysTyr: 3.398 ± 0.76
0.0LysXaa: 0.0 ± 0.0
Leu
5.947LeuAla: 5.947 ± 0.983
2.124LeuCys: 2.124 ± 1.586
5.523LeuAsp: 5.523 ± 1.823
4.248LeuGlu: 4.248 ± 1.542
8.496LeuPhe: 8.496 ± 2.636
5.098LeuGly: 5.098 ± 2.798
1.699LeuHis: 1.699 ± 0.865
2.549LeuIle: 2.549 ± 1.397
3.823LeuLys: 3.823 ± 1.062
9.346LeuLeu: 9.346 ± 2.527
0.85LeuMet: 0.85 ± 0.709
2.549LeuAsn: 2.549 ± 0.685
5.098LeuPro: 5.098 ± 1.229
6.372LeuGln: 6.372 ± 1.011
6.797LeuArg: 6.797 ± 1.695
10.62LeuSer: 10.62 ± 3.263
6.372LeuThr: 6.372 ± 1.571
7.222LeuVal: 7.222 ± 0.849
0.85LeuTrp: 0.85 ± 0.678
3.398LeuTyr: 3.398 ± 1.01
0.0LeuXaa: 0.0 ± 0.0
Met
1.699MetAla: 1.699 ± 0.782
0.425MetCys: 0.425 ± 0.338
0.85MetAsp: 0.85 ± 0.4
0.425MetGlu: 0.425 ± 0.399
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.425MetIle: 0.425 ± 0.512
0.425MetLys: 0.425 ± 0.556
2.124MetLeu: 2.124 ± 0.809
0.0MetMet: 0.0 ± 0.0
0.85MetAsn: 0.85 ± 0.799
0.0MetPro: 0.0 ± 0.0
0.425MetGln: 0.425 ± 0.338
0.0MetArg: 0.0 ± 0.0
1.274MetSer: 1.274 ± 0.713
0.425MetThr: 0.425 ± 0.338
1.699MetVal: 1.699 ± 0.92
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.274AsnAla: 1.274 ± 1.013
0.425AsnCys: 0.425 ± 0.338
2.124AsnAsp: 2.124 ± 0.681
2.124AsnGlu: 2.124 ± 0.669
2.124AsnPhe: 2.124 ± 0.712
2.549AsnGly: 2.549 ± 1.195
0.425AsnHis: 0.425 ± 0.512
0.85AsnIle: 0.85 ± 0.642
2.124AsnLys: 2.124 ± 1.018
3.398AsnLeu: 3.398 ± 1.619
0.425AsnMet: 0.425 ± 0.399
1.274AsnAsn: 1.274 ± 0.725
3.398AsnPro: 3.398 ± 1.548
2.124AsnGln: 2.124 ± 0.669
1.274AsnArg: 1.274 ± 0.473
2.124AsnSer: 2.124 ± 1.043
2.549AsnThr: 2.549 ± 1.401
2.124AsnVal: 2.124 ± 1.1
0.425AsnTrp: 0.425 ± 0.603
0.425AsnTyr: 0.425 ± 0.399
0.0AsnXaa: 0.0 ± 0.0
Pro
5.947ProAla: 5.947 ± 1.886
0.85ProCys: 0.85 ± 0.618
5.098ProAsp: 5.098 ± 1.472
2.974ProGlu: 2.974 ± 1.066
2.124ProPhe: 2.124 ± 0.717
1.699ProGly: 1.699 ± 0.937
0.425ProHis: 0.425 ± 0.394
2.124ProIle: 2.124 ± 1.018
4.248ProLys: 4.248 ± 1.371
7.222ProLeu: 7.222 ± 3.065
0.0ProMet: 0.0 ± 0.0
2.974ProAsn: 2.974 ± 0.939
9.771ProPro: 9.771 ± 3.113
2.974ProGln: 2.974 ± 0.921
5.098ProArg: 5.098 ± 1.957
4.673ProSer: 4.673 ± 2.168
4.673ProThr: 4.673 ± 1.51
1.274ProVal: 1.274 ± 0.74
0.0ProTrp: 0.0 ± 0.0
1.699ProTyr: 1.699 ± 0.757
0.0ProXaa: 0.0 ± 0.0
Gln
2.124GlnAla: 2.124 ± 0.669
0.85GlnCys: 0.85 ± 0.488
1.699GlnAsp: 1.699 ± 0.655
2.974GlnGlu: 2.974 ± 1.022
1.274GlnPhe: 1.274 ± 1.013
2.549GlnGly: 2.549 ± 0.736
0.425GlnHis: 0.425 ± 0.603
2.974GlnIle: 2.974 ± 0.526
3.398GlnLys: 3.398 ± 1.375
8.071GlnLeu: 8.071 ± 1.6
0.0GlnMet: 0.0 ± 0.0
1.274GlnAsn: 1.274 ± 0.725
2.974GlnPro: 2.974 ± 0.641
3.823GlnGln: 3.823 ± 0.83
2.124GlnArg: 2.124 ± 0.923
2.549GlnSer: 2.549 ± 1.009
3.398GlnThr: 3.398 ± 1.202
1.699GlnVal: 1.699 ± 0.676
0.85GlnTrp: 0.85 ± 0.469
2.974GlnTyr: 2.974 ± 1.202
0.0GlnXaa: 0.0 ± 0.0
Arg
3.398ArgAla: 3.398 ± 0.848
1.699ArgCys: 1.699 ± 1.281
4.248ArgAsp: 4.248 ± 1.356
3.823ArgGlu: 3.823 ± 1.256
2.974ArgPhe: 2.974 ± 1.118
3.823ArgGly: 3.823 ± 1.29
2.124ArgHis: 2.124 ± 0.836
1.699ArgIle: 1.699 ± 0.673
3.823ArgLys: 3.823 ± 1.031
5.947ArgLeu: 5.947 ± 1.557
0.85ArgMet: 0.85 ± 0.469
1.274ArgAsn: 1.274 ± 0.58
5.947ArgPro: 5.947 ± 1.427
0.425ArgGln: 0.425 ± 0.603
6.372ArgArg: 6.372 ± 2.903
4.673ArgSer: 4.673 ± 0.503
4.248ArgThr: 4.248 ± 0.591
3.398ArgVal: 3.398 ± 1.003
1.699ArgTrp: 1.699 ± 0.766
3.398ArgTyr: 3.398 ± 1.364
0.0ArgXaa: 0.0 ± 0.0
Ser
1.274SerAla: 1.274 ± 0.693
0.85SerCys: 0.85 ± 0.615
7.647SerAsp: 7.647 ± 1.082
4.248SerGlu: 4.248 ± 2.01
5.523SerPhe: 5.523 ± 1.652
4.673SerGly: 4.673 ± 1.566
1.274SerHis: 1.274 ± 0.646
2.549SerIle: 2.549 ± 0.987
3.823SerLys: 3.823 ± 2.32
9.771SerLeu: 9.771 ± 1.143
0.85SerMet: 0.85 ± 0.698
1.274SerAsn: 1.274 ± 0.736
5.098SerPro: 5.098 ± 1.128
3.398SerGln: 3.398 ± 1.338
8.921SerArg: 8.921 ± 1.853
4.248SerSer: 4.248 ± 0.976
5.947SerThr: 5.947 ± 1.708
5.947SerVal: 5.947 ± 1.165
0.85SerTrp: 0.85 ± 0.676
0.425SerTyr: 0.425 ± 0.399
0.0SerXaa: 0.0 ± 0.0
Thr
2.974ThrAla: 2.974 ± 1.083
0.85ThrCys: 0.85 ± 0.415
3.823ThrAsp: 3.823 ± 1.859
5.523ThrGlu: 5.523 ± 0.868
1.699ThrPhe: 1.699 ± 1.152
3.823ThrGly: 3.823 ± 0.911
0.85ThrHis: 0.85 ± 0.676
4.248ThrIle: 4.248 ± 2.019
1.699ThrLys: 1.699 ± 0.8
4.248ThrLeu: 4.248 ± 1.1
1.274ThrMet: 1.274 ± 0.623
1.274ThrAsn: 1.274 ± 0.58
6.797ThrPro: 6.797 ± 1.949
1.274ThrGln: 1.274 ± 0.473
5.523ThrArg: 5.523 ± 1.263
3.823ThrSer: 3.823 ± 0.796
5.947ThrThr: 5.947 ± 2.245
4.248ThrVal: 4.248 ± 0.972
0.85ThrTrp: 0.85 ± 0.798
2.124ThrTyr: 2.124 ± 0.669
0.0ThrXaa: 0.0 ± 0.0
Val
2.124ValAla: 2.124 ± 0.57
2.124ValCys: 2.124 ± 1.057
5.523ValAsp: 5.523 ± 0.978
3.398ValGlu: 3.398 ± 0.913
2.549ValPhe: 2.549 ± 0.855
2.124ValGly: 2.124 ± 1.583
0.425ValHis: 0.425 ± 0.394
2.974ValIle: 2.974 ± 0.859
2.549ValLys: 2.549 ± 0.785
4.673ValLeu: 4.673 ± 1.448
0.425ValMet: 0.425 ± 0.303
1.699ValAsn: 1.699 ± 0.92
3.398ValPro: 3.398 ± 1.353
2.124ValGln: 2.124 ± 0.878
4.673ValArg: 4.673 ± 1.283
4.673ValSer: 4.673 ± 0.938
4.248ValThr: 4.248 ± 2.527
2.124ValVal: 2.124 ± 0.803
1.699ValTrp: 1.699 ± 0.782
1.274ValTyr: 1.274 ± 0.692
0.0ValXaa: 0.0 ± 0.0
Trp
1.274TrpAla: 1.274 ± 0.623
0.425TrpCys: 0.425 ± 0.399
0.425TrpAsp: 0.425 ± 0.338
0.425TrpGlu: 0.425 ± 0.399
0.0TrpPhe: 0.0 ± 0.0
1.274TrpGly: 1.274 ± 0.713
0.425TrpHis: 0.425 ± 0.399
1.699TrpIle: 1.699 ± 0.8
0.85TrpLys: 0.85 ± 0.676
0.85TrpLeu: 0.85 ± 0.4
0.0TrpMet: 0.0 ± 0.0
0.425TrpAsn: 0.425 ± 0.399
0.425TrpPro: 0.425 ± 0.603
0.85TrpGln: 0.85 ± 0.798
0.425TrpArg: 0.425 ± 0.556
0.425TrpSer: 0.425 ± 0.399
1.699TrpThr: 1.699 ± 0.945
1.274TrpVal: 1.274 ± 0.623
0.0TrpTrp: 0.0 ± 0.0
0.425TrpTyr: 0.425 ± 0.338
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.274TyrAla: 1.274 ± 0.725
0.85TyrCys: 0.85 ± 0.469
1.274TyrAsp: 1.274 ± 0.376
1.699TyrGlu: 1.699 ± 0.929
3.398TyrPhe: 3.398 ± 0.992
2.974TyrGly: 2.974 ± 0.718
0.425TyrHis: 0.425 ± 0.399
1.699TyrIle: 1.699 ± 0.726
2.549TyrLys: 2.549 ± 1.449
3.823TyrLeu: 3.823 ± 0.961
0.425TyrMet: 0.425 ± 0.302
0.425TyrAsn: 0.425 ± 0.394
2.124TyrPro: 2.124 ± 1.003
0.425TyrGln: 0.425 ± 0.359
2.124TyrArg: 2.124 ± 1.062
2.549TyrSer: 2.549 ± 1.062
0.425TyrThr: 0.425 ± 0.338
2.124TyrVal: 2.124 ± 0.909
0.425TyrTrp: 0.425 ± 0.399
3.823TyrTyr: 3.823 ± 1.298
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (2355 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski