Amino acid dipepetide frequency for Flavimobilis soli

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	22.11AlaAla: 22.11 ± 0.275	0.897AlaCys: 0.897 ± 0.037	8.384AlaAsp: 8.384 ± 0.115	8.262AlaGlu: 8.262 ± 0.113	3.357AlaPhe: 3.357 ± 0.062	12.582AlaGly: 12.582 ± 0.169	2.735AlaHis: 2.735 ± 0.064	4.571AlaIle: 4.571 ± 0.071	2.816AlaLys: 2.816 ± 0.082	14.174AlaLeu: 14.174 ± 0.176	2.586AlaMet: 2.586 ± 0.06	2.071AlaAsn: 2.071 ± 0.051	7.981AlaPro: 7.981 ± 0.143	4.333AlaGln: 4.333 ± 0.088	10.836AlaArg: 10.836 ± 0.121	7.454AlaSer: 7.454 ± 0.094	8.458AlaThr: 8.458 ± 0.126	12.688AlaVal: 12.688 ± 0.169	1.95AlaTrp: 1.95 ± 0.051	2.329AlaTyr: 2.329 ± 0.063	0.0AlaXaa: 0.0 ± 0.0
Cys	0.783CysAla: 0.783 ± 0.031	0.055CysCys: 0.055 ± 0.008	0.342CysAsp: 0.342 ± 0.019	0.318CysGlu: 0.318 ± 0.02	0.172CysPhe: 0.172 ± 0.014	0.636CysGly: 0.636 ± 0.03	0.125CysHis: 0.125 ± 0.013	0.17CysIle: 0.17 ± 0.015	0.091CysLys: 0.091 ± 0.01	0.505CysLeu: 0.505 ± 0.027	0.078CysMet: 0.078 ± 0.01	0.109CysAsn: 0.109 ± 0.013	0.359CysPro: 0.359 ± 0.022	0.139CysGln: 0.139 ± 0.015	0.385CysArg: 0.385 ± 0.023	0.376CysSer: 0.376 ± 0.024	0.404CysThr: 0.404 ± 0.026	0.504CysVal: 0.504 ± 0.028	0.076CysTrp: 0.076 ± 0.009	0.11CysTyr: 0.11 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	9.343AspAla: 9.343 ± 0.124	0.271AspCys: 0.271 ± 0.017	4.716AspAsp: 4.716 ± 0.089	4.521AspGlu: 4.521 ± 0.074	1.408AspPhe: 1.408 ± 0.04	6.823AspGly: 6.823 ± 0.106	1.183AspHis: 1.183 ± 0.043	1.733AspIle: 1.733 ± 0.055	1.085AspLys: 1.085 ± 0.045	6.792AspLeu: 6.792 ± 0.098	0.881AspMet: 0.881 ± 0.037	0.822AspAsn: 0.822 ± 0.032	3.95AspPro: 3.95 ± 0.07	1.439AspGln: 1.439 ± 0.043	4.175AspArg: 4.175 ± 0.073	2.383AspSer: 2.383 ± 0.058	2.691AspThr: 2.691 ± 0.06	7.134AspVal: 7.134 ± 0.1	0.718AspTrp: 0.718 ± 0.032	1.04AspTyr: 1.04 ± 0.038	0.0AspXaa: 0.0 ± 0.0
Glu	7.363GluAla: 7.363 ± 0.113	0.285GluCys: 0.285 ± 0.02	3.171GluAsp: 3.171 ± 0.067	3.121GluGlu: 3.121 ± 0.07	1.2GluPhe: 1.2 ± 0.046	4.434GluGly: 4.434 ± 0.08	1.65GluHis: 1.65 ± 0.049	2.632GluIle: 2.632 ± 0.065	1.391GluLys: 1.391 ± 0.048	6.349GluLeu: 6.349 ± 0.106	0.989GluMet: 0.989 ± 0.037	1.109GluAsn: 1.109 ± 0.036	3.376GluPro: 3.376 ± 0.077	2.221GluGln: 2.221 ± 0.056	5.387GluArg: 5.387 ± 0.097	2.575GluSer: 2.575 ± 0.059	3.032GluThr: 3.032 ± 0.057	5.292GluVal: 5.292 ± 0.089	0.637GluTrp: 0.637 ± 0.033	0.909GluTyr: 0.909 ± 0.034	0.0GluXaa: 0.0 ± 0.0
Phe	3.478PheAla: 3.478 ± 0.061	0.193PheCys: 0.193 ± 0.014	1.899PheAsp: 1.899 ± 0.052	1.521PheGlu: 1.521 ± 0.05	0.892PhePhe: 0.892 ± 0.037	2.649PheGly: 2.649 ± 0.062	0.483PheHis: 0.483 ± 0.025	0.775PheIle: 0.775 ± 0.029	0.486PheLys: 0.486 ± 0.03	2.391PheLeu: 2.391 ± 0.057	0.418PheMet: 0.418 ± 0.019	0.509PheAsn: 0.509 ± 0.025	1.263PhePro: 1.263 ± 0.043	0.623PheGln: 0.623 ± 0.026	1.556PheArg: 1.556 ± 0.039	1.499PheSer: 1.499 ± 0.043	1.803PheThr: 1.803 ± 0.046	2.618PheVal: 2.618 ± 0.058	0.371PheTrp: 0.371 ± 0.021	0.533PheTyr: 0.533 ± 0.026	0.0PheXaa: 0.0 ± 0.0
Gly	12.022GlyAla: 12.022 ± 0.165	0.583GlyCys: 0.583 ± 0.027	5.104GlyAsp: 5.104 ± 0.08	4.96GlyGlu: 4.96 ± 0.085	2.656GlyPhe: 2.656 ± 0.058	7.681GlyGly: 7.681 ± 0.125	1.823GlyHis: 1.823 ± 0.056	3.461GlyIle: 3.461 ± 0.062	2.454GlyLys: 2.454 ± 0.072	8.779GlyLeu: 8.779 ± 0.126	1.924GlyMet: 1.924 ± 0.046	1.486GlyAsn: 1.486 ± 0.046	4.356GlyPro: 4.356 ± 0.071	2.466GlyGln: 2.466 ± 0.066	6.813GlyArg: 6.813 ± 0.104	5.272GlySer: 5.272 ± 0.089	6.33GlyThr: 6.33 ± 0.099	8.397GlyVal: 8.397 ± 0.098	1.514GlyTrp: 1.514 ± 0.048	2.042GlyTyr: 2.042 ± 0.05	0.0GlyXaa: 0.0 ± 0.0
His	2.612HisAla: 2.612 ± 0.058	0.113HisCys: 0.113 ± 0.011	1.442HisAsp: 1.442 ± 0.045	1.255HisGlu: 1.255 ± 0.041	0.438HisPhe: 0.438 ± 0.025	1.999HisGly: 1.999 ± 0.057	0.537HisHis: 0.537 ± 0.025	0.479HisIle: 0.479 ± 0.024	0.264HisLys: 0.264 ± 0.019	2.257HisLeu: 2.257 ± 0.052	0.291HisMet: 0.291 ± 0.017	0.306HisAsn: 0.306 ± 0.018	1.354HisPro: 1.354 ± 0.051	0.493HisGln: 0.493 ± 0.025	1.432HisArg: 1.432 ± 0.045	0.853HisSer: 0.853 ± 0.037	0.989HisThr: 0.989 ± 0.034	2.217HisVal: 2.217 ± 0.051	0.236HisTrp: 0.236 ± 0.017	0.339HisTyr: 0.339 ± 0.018	0.0HisXaa: 0.0 ± 0.0
Ile	5.09IleAla: 5.09 ± 0.093	0.194IleCys: 0.194 ± 0.015	2.776IleAsp: 2.776 ± 0.058	2.343IleGlu: 2.343 ± 0.067	0.83IlePhe: 0.83 ± 0.036	3.378IleGly: 3.378 ± 0.069	0.517IleHis: 0.517 ± 0.026	1.222IleIle: 1.222 ± 0.041	0.805IleLys: 0.805 ± 0.035	2.864IleLeu: 2.864 ± 0.069	0.515IleMet: 0.515 ± 0.024	0.765IleAsn: 0.765 ± 0.031	1.663IlePro: 1.663 ± 0.046	0.72IleGln: 0.72 ± 0.029	1.902IleArg: 1.902 ± 0.052	1.744IleSer: 1.744 ± 0.047	2.348IleThr: 2.348 ± 0.056	3.728IleVal: 3.728 ± 0.076	0.31IleTrp: 0.31 ± 0.019	0.547IleTyr: 0.547 ± 0.03	0.0IleXaa: 0.0 ± 0.0
Lys	2.71LysAla: 2.71 ± 0.074	0.099LysCys: 0.099 ± 0.012	1.288LysAsp: 1.288 ± 0.053	0.999LysGlu: 0.999 ± 0.043	0.487LysPhe: 0.487 ± 0.026	1.685LysGly: 1.685 ± 0.057	0.454LysHis: 0.454 ± 0.024	0.974LysIle: 0.974 ± 0.043	0.981LysLys: 0.981 ± 0.057	1.769LysLeu: 1.769 ± 0.052	0.353LysMet: 0.353 ± 0.019	0.548LysAsn: 0.548 ± 0.03	1.156LysPro: 1.156 ± 0.047	0.58LysGln: 0.58 ± 0.024	1.4LysArg: 1.4 ± 0.046	1.19LysSer: 1.19 ± 0.045	1.238LysThr: 1.238 ± 0.049	2.237LysVal: 2.237 ± 0.082	0.17LysTrp: 0.17 ± 0.014	0.444LysTyr: 0.444 ± 0.026	0.0LysXaa: 0.0 ± 0.0
Leu	15.536LeuAla: 15.536 ± 0.182	0.547LeuCys: 0.547 ± 0.031	7.182LeuAsp: 7.182 ± 0.103	5.47LeuGlu: 5.47 ± 0.096	2.359LeuPhe: 2.359 ± 0.061	9.403LeuGly: 9.403 ± 0.133	1.741LeuHis: 1.741 ± 0.044	2.623LeuIle: 2.623 ± 0.062	1.68LeuLys: 1.68 ± 0.056	9.803LeuLeu: 9.803 ± 0.168	1.609LeuMet: 1.609 ± 0.052	1.493LeuAsn: 1.493 ± 0.046	5.732LeuPro: 5.732 ± 0.092	2.053LeuGln: 2.053 ± 0.05	7.521LeuArg: 7.521 ± 0.117	5.159LeuSer: 5.159 ± 0.087	6.563LeuThr: 6.563 ± 0.084	10.938LeuVal: 10.938 ± 0.16	1.141LeuTrp: 1.141 ± 0.039	1.374LeuTyr: 1.374 ± 0.04	0.0LeuXaa: 0.0 ± 0.0
Met	1.977MetAla: 1.977 ± 0.054	0.105MetCys: 0.105 ± 0.012	0.805MetAsp: 0.805 ± 0.033	0.609MetGlu: 0.609 ± 0.03	0.471MetPhe: 0.471 ± 0.024	1.199MetGly: 1.199 ± 0.036	0.338MetHis: 0.338 ± 0.02	0.787MetIle: 0.787 ± 0.029	0.378MetLys: 0.378 ± 0.019	1.798MetLeu: 1.798 ± 0.046	0.281MetMet: 0.281 ± 0.02	0.407MetAsn: 0.407 ± 0.022	0.995MetPro: 0.995 ± 0.035	0.457MetGln: 0.457 ± 0.023	1.382MetArg: 1.382 ± 0.04	1.498MetSer: 1.498 ± 0.042	1.806MetThr: 1.806 ± 0.049	1.394MetVal: 1.394 ± 0.039	0.171MetTrp: 0.171 ± 0.014	0.284MetTyr: 0.284 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	2.117AsnAla: 2.117 ± 0.049	0.08AsnCys: 0.08 ± 0.009	1.044AsnAsp: 1.044 ± 0.038	0.869AsnGlu: 0.869 ± 0.033	0.472AsnPhe: 0.472 ± 0.027	1.499AsnGly: 1.499 ± 0.047	0.356AsnHis: 0.356 ± 0.022	0.707AsnIle: 0.707 ± 0.032	0.403AsnLys: 0.403 ± 0.026	1.873AsnLeu: 1.873 ± 0.053	0.313AsnMet: 0.313 ± 0.018	0.382AsnAsn: 0.382 ± 0.02	1.36AsnPro: 1.36 ± 0.045	0.512AsnGln: 0.512 ± 0.023	1.121AsnArg: 1.121 ± 0.036	0.644AsnSer: 0.644 ± 0.029	0.87AsnThr: 0.87 ± 0.035	1.652AsnVal: 1.652 ± 0.051	0.188AsnTrp: 0.188 ± 0.015	0.336AsnTyr: 0.336 ± 0.021	0.0AsnXaa: 0.0 ± 0.0
Pro	8.408ProAla: 8.408 ± 0.135	0.236ProCys: 0.236 ± 0.017	4.176ProAsp: 4.176 ± 0.073	3.972ProGlu: 3.972 ± 0.08	1.482ProPhe: 1.482 ± 0.041	5.76ProGly: 5.76 ± 0.083	1.157ProHis: 1.157 ± 0.033	1.344ProIle: 1.344 ± 0.034	0.959ProLys: 0.959 ± 0.043	4.681ProLeu: 4.681 ± 0.079	0.769ProMet: 0.769 ± 0.03	0.831ProAsn: 0.831 ± 0.031	2.462ProPro: 2.462 ± 0.072	1.595ProGln: 1.595 ± 0.045	3.712ProArg: 3.712 ± 0.072	3.43ProSer: 3.43 ± 0.075	3.909ProThr: 3.909 ± 0.084	5.656ProVal: 5.656 ± 0.096	0.834ProTrp: 0.834 ± 0.032	0.996ProTyr: 0.996 ± 0.037	0.0ProXaa: 0.0 ± 0.0
Gln	3.529GlnAla: 3.529 ± 0.07	0.115GlnCys: 0.115 ± 0.012	1.469GlnAsp: 1.469 ± 0.05	1.36GlnGlu: 1.36 ± 0.041	0.621GlnPhe: 0.621 ± 0.029	2.072GlnGly: 2.072 ± 0.049	0.616GlnHis: 0.616 ± 0.027	1.196GlnIle: 1.196 ± 0.035	0.552GlnLys: 0.552 ± 0.028	2.783GlnLeu: 2.783 ± 0.062	0.494GlnMet: 0.494 ± 0.023	0.481GlnAsn: 0.481 ± 0.026	1.514GlnPro: 1.514 ± 0.051	0.975GlnGln: 0.975 ± 0.038	2.23GlnArg: 2.23 ± 0.051	1.202GlnSer: 1.202 ± 0.041	1.472GlnThr: 1.472 ± 0.039	3.034GlnVal: 3.034 ± 0.055	0.38GlnTrp: 0.38 ± 0.019	0.528GlnTyr: 0.528 ± 0.031	0.0GlnXaa: 0.0 ± 0.0
Arg	10.017ArgAla: 10.017 ± 0.143	0.419ArgCys: 0.419 ± 0.025	4.275ArgAsp: 4.275 ± 0.079	4.453ArgGlu: 4.453 ± 0.091	2.074ArgPhe: 2.074 ± 0.056	5.878ArgGly: 5.878 ± 0.099	1.501ArgHis: 1.501 ± 0.045	2.761ArgIle: 2.761 ± 0.068	1.496ArgLys: 1.496 ± 0.048	7.623ArgLeu: 7.623 ± 0.119	1.62ArgMet: 1.62 ± 0.043	1.197ArgAsn: 1.197 ± 0.039	4.161ArgPro: 4.161 ± 0.074	1.821ArgGln: 1.821 ± 0.043	6.963ArgArg: 6.963 ± 0.121	4.322ArgSer: 4.322 ± 0.083	5.105ArgThr: 5.105 ± 0.079	6.434ArgVal: 6.434 ± 0.083	1.286ArgTrp: 1.286 ± 0.042	1.505ArgTyr: 1.505 ± 0.045	0.0ArgXaa: 0.0 ± 0.0
Ser	7.002SerAla: 7.002 ± 0.095	0.343SerCys: 0.343 ± 0.023	2.942SerAsp: 2.942 ± 0.06	2.501SerGlu: 2.501 ± 0.062	1.714SerPhe: 1.714 ± 0.05	5.632SerGly: 5.632 ± 0.088	1.009SerHis: 1.009 ± 0.032	2.014SerIle: 2.014 ± 0.048	1.086SerLys: 1.086 ± 0.045	5.175SerLeu: 5.175 ± 0.073	1.097SerMet: 1.097 ± 0.038	0.962SerAsn: 0.962 ± 0.038	2.959SerPro: 2.959 ± 0.059	1.391SerGln: 1.391 ± 0.049	3.807SerArg: 3.807 ± 0.066	3.445SerSer: 3.445 ± 0.076	3.864SerThr: 3.864 ± 0.081	4.811SerVal: 4.811 ± 0.068	0.901SerTrp: 0.901 ± 0.038	1.178SerTyr: 1.178 ± 0.042	0.0SerXaa: 0.0 ± 0.0
Thr	8.307ThrAla: 8.307 ± 0.12	0.349ThrCys: 0.349 ± 0.022	3.595ThrAsp: 3.595 ± 0.067	3.104ThrGlu: 3.104 ± 0.074	1.991ThrPhe: 1.991 ± 0.049	5.941ThrGly: 5.941 ± 0.098	1.148ThrHis: 1.148 ± 0.039	2.703ThrIle: 2.703 ± 0.059	1.404ThrLys: 1.404 ± 0.053	6.195ThrLeu: 6.195 ± 0.111	0.974ThrMet: 0.974 ± 0.035	1.111ThrAsn: 1.111 ± 0.039	4.262ThrPro: 4.262 ± 0.097	1.595ThrGln: 1.595 ± 0.043	3.965ThrArg: 3.965 ± 0.073	3.992ThrSer: 3.992 ± 0.076	4.98ThrThr: 4.98 ± 0.106	6.644ThrVal: 6.644 ± 0.109	1.012ThrTrp: 1.012 ± 0.041	1.312ThrTyr: 1.312 ± 0.037	0.0ThrXaa: 0.0 ± 0.0
Val	14.379ValAla: 14.379 ± 0.161	0.604ValCys: 0.604 ± 0.028	6.414ValAsp: 6.414 ± 0.089	5.714ValGlu: 5.714 ± 0.091	2.301ValPhe: 2.301 ± 0.053	8.111ValGly: 8.111 ± 0.114	1.963ValHis: 1.963 ± 0.05	3.172ValIle: 3.172 ± 0.077	1.777ValLys: 1.777 ± 0.06	10.666ValLeu: 10.666 ± 0.148	1.503ValMet: 1.503 ± 0.051	1.559ValAsn: 1.559 ± 0.049	5.904ValPro: 5.904 ± 0.09	2.229ValGln: 2.229 ± 0.049	7.684ValArg: 7.684 ± 0.11	4.932ValSer: 4.932 ± 0.078	6.725ValThr: 6.725 ± 0.133	12.192ValVal: 12.192 ± 0.169	1.189ValTrp: 1.189 ± 0.044	1.532ValTyr: 1.532 ± 0.041	0.0ValXaa: 0.0 ± 0.0
Trp	1.519TrpAla: 1.519 ± 0.044	0.123TrpCys: 0.123 ± 0.013	0.861TrpAsp: 0.861 ± 0.032	0.622TrpGlu: 0.622 ± 0.028	0.497TrpPhe: 0.497 ± 0.026	0.982TrpGly: 0.982 ± 0.038	0.281TrpHis: 0.281 ± 0.02	0.489TrpIle: 0.489 ± 0.024	0.284TrpLys: 0.284 ± 0.019	1.477TrpLeu: 1.477 ± 0.05	0.225TrpMet: 0.225 ± 0.018	0.322TrpAsn: 0.322 ± 0.022	0.647TrpPro: 0.647 ± 0.025	0.476TrpGln: 0.476 ± 0.024	1.215TrpArg: 1.215 ± 0.046	0.883TrpSer: 0.883 ± 0.036	0.971TrpThr: 0.971 ± 0.034	1.204TrpVal: 1.204 ± 0.038	0.307TrpTrp: 0.307 ± 0.019	0.285TrpTyr: 0.285 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.274TyrAla: 2.274 ± 0.048	0.128TyrCys: 0.128 ± 0.011	1.222TyrAsp: 1.222 ± 0.036	1.149TyrGlu: 1.149 ± 0.045	0.54TyrPhe: 0.54 ± 0.024	1.778TyrGly: 1.778 ± 0.048	0.285TyrHis: 0.285 ± 0.019	0.451TyrIle: 0.451 ± 0.028	0.371TyrLys: 0.371 ± 0.023	1.974TyrLeu: 1.974 ± 0.044	0.218TyrMet: 0.218 ± 0.015	0.329TyrAsn: 0.329 ± 0.021	0.916TyrPro: 0.916 ± 0.033	0.502TyrGln: 0.502 ± 0.025	1.425TyrArg: 1.425 ± 0.043	0.978TyrSer: 0.978 ± 0.038	1.025TyrThr: 1.025 ± 0.04	1.774TyrVal: 1.774 ± 0.044	0.281TyrTrp: 0.281 ± 0.018	0.421TyrTyr: 0.421 ± 0.023	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2501 proteins (860565 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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