Amino acid dipepetide frequency for Capsulimonas corticalis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	15.629AlaAla: 15.629 ± 0.14	1.016AlaCys: 1.016 ± 0.022	6.098AlaAsp: 6.098 ± 0.062	5.917AlaGlu: 5.917 ± 0.066	3.73AlaPhe: 3.73 ± 0.042	9.255AlaGly: 9.255 ± 0.074	2.596AlaHis: 2.596 ± 0.033	5.829AlaIle: 5.829 ± 0.065	3.983AlaLys: 3.983 ± 0.049	11.787AlaLeu: 11.787 ± 0.083	2.675AlaMet: 2.675 ± 0.033	3.455AlaAsn: 3.455 ± 0.045	6.548AlaPro: 6.548 ± 0.073	4.652AlaGln: 4.652 ± 0.055	7.09AlaArg: 7.09 ± 0.079	6.953AlaSer: 6.953 ± 0.068	5.99AlaThr: 5.99 ± 0.063	7.519AlaVal: 7.519 ± 0.071	1.52AlaTrp: 1.52 ± 0.027	2.887AlaTyr: 2.887 ± 0.038	0.0AlaXaa: 0.0 ± 0.0
Cys	1.18CysAla: 1.18 ± 0.026	0.133CysCys: 0.133 ± 0.009	0.584CysAsp: 0.584 ± 0.017	0.451CysGlu: 0.451 ± 0.014	0.336CysPhe: 0.336 ± 0.012	0.974CysGly: 0.974 ± 0.021	0.23CysHis: 0.23 ± 0.011	0.41CysIle: 0.41 ± 0.014	0.229CysLys: 0.229 ± 0.01	0.958CysLeu: 0.958 ± 0.021	0.162CysMet: 0.162 ± 0.008	0.26CysAsn: 0.26 ± 0.012	0.589CysPro: 0.589 ± 0.019	0.271CysGln: 0.271 ± 0.012	0.628CysArg: 0.628 ± 0.02	0.496CysSer: 0.496 ± 0.014	0.404CysThr: 0.404 ± 0.014	0.758CysVal: 0.758 ± 0.017	0.16CysTrp: 0.16 ± 0.009	0.331CysTyr: 0.331 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	6.681AspAla: 6.681 ± 0.064	0.516AspCys: 0.516 ± 0.017	3.253AspAsp: 3.253 ± 0.043	3.173AspGlu: 3.173 ± 0.039	2.077AspPhe: 2.077 ± 0.03	5.418AspGly: 5.418 ± 0.06	1.241AspHis: 1.241 ± 0.025	3.065AspIle: 3.065 ± 0.039	1.914AspLys: 1.914 ± 0.032	5.577AspLeu: 5.577 ± 0.056	1.023AspMet: 1.023 ± 0.021	1.805AspAsn: 1.805 ± 0.033	3.556AspPro: 3.556 ± 0.045	1.91AspGln: 1.91 ± 0.03	3.378AspArg: 3.378 ± 0.043	3.014AspSer: 3.014 ± 0.039	3.145AspThr: 3.145 ± 0.04	3.885AspVal: 3.885 ± 0.047	1.104AspTrp: 1.104 ± 0.026	1.82AspTyr: 1.82 ± 0.028	0.0AspXaa: 0.0 ± 0.0
Glu	6.022GluAla: 6.022 ± 0.064	0.475GluCys: 0.475 ± 0.014	2.67GluAsp: 2.67 ± 0.039	3.199GluGlu: 3.199 ± 0.051	1.85GluPhe: 1.85 ± 0.029	3.474GluGly: 3.474 ± 0.046	1.226GluHis: 1.226 ± 0.024	3.485GluIle: 3.485 ± 0.048	2.181GluLys: 2.181 ± 0.04	4.453GluLeu: 4.453 ± 0.057	1.608GluMet: 1.608 ± 0.029	1.788GluAsn: 1.788 ± 0.03	2.282GluPro: 2.282 ± 0.035	2.077GluGln: 2.077 ± 0.033	4.111GluArg: 4.111 ± 0.061	2.696GluSer: 2.696 ± 0.038	3.569GluThr: 3.569 ± 0.043	3.146GluVal: 3.146 ± 0.044	0.886GluTrp: 0.886 ± 0.02	1.535GluTyr: 1.535 ± 0.025	0.0GluXaa: 0.0 ± 0.0
Phe	3.894PheAla: 3.894 ± 0.041	0.456PheCys: 0.456 ± 0.017	2.376PheAsp: 2.376 ± 0.036	1.783PheGlu: 1.783 ± 0.032	1.278PhePhe: 1.278 ± 0.026	3.048PheGly: 3.048 ± 0.042	0.955PheHis: 0.955 ± 0.023	1.342PheIle: 1.342 ± 0.03	0.9PheLys: 0.9 ± 0.022	3.373PheLeu: 3.373 ± 0.04	0.607PheMet: 0.607 ± 0.015	1.115PheAsn: 1.115 ± 0.024	1.821PhePro: 1.821 ± 0.03	1.34PheGln: 1.34 ± 0.026	1.831PheArg: 1.831 ± 0.026	2.271PheSer: 2.271 ± 0.033	2.371PheThr: 2.371 ± 0.04	2.552PheVal: 2.552 ± 0.037	0.638PheTrp: 0.638 ± 0.015	1.171PheTyr: 1.171 ± 0.025	0.0PheXaa: 0.0 ± 0.0
Gly	9.595GlyAla: 9.595 ± 0.073	0.853GlyCys: 0.853 ± 0.02	4.976GlyAsp: 4.976 ± 0.055	4.096GlyGlu: 4.096 ± 0.048	3.083GlyPhe: 3.083 ± 0.043	7.741GlyGly: 7.741 ± 0.092	1.869GlyHis: 1.869 ± 0.032	3.6GlyIle: 3.6 ± 0.047	3.466GlyLys: 3.466 ± 0.051	7.068GlyLeu: 7.068 ± 0.066	1.916GlyMet: 1.916 ± 0.03	2.688GlyAsn: 2.688 ± 0.043	3.125GlyPro: 3.125 ± 0.05	2.871GlyGln: 2.871 ± 0.041	4.828GlyArg: 4.828 ± 0.048	5.034GlySer: 5.034 ± 0.069	4.103GlyThr: 4.103 ± 0.059	6.909GlyVal: 6.909 ± 0.068	1.414GlyTrp: 1.414 ± 0.026	2.842GlyTyr: 2.842 ± 0.041	0.0GlyXaa: 0.0 ± 0.0
His	2.334HisAla: 2.334 ± 0.034	0.248HisCys: 0.248 ± 0.01	1.289HisAsp: 1.289 ± 0.025	1.118HisGlu: 1.118 ± 0.023	0.882HisPhe: 0.882 ± 0.022	2.102HisGly: 2.102 ± 0.034	0.638HisHis: 0.638 ± 0.019	1.096HisIle: 1.096 ± 0.023	0.651HisLys: 0.651 ± 0.017	2.208HisLeu: 2.208 ± 0.033	0.455HisMet: 0.455 ± 0.015	0.675HisAsn: 0.675 ± 0.019	1.481HisPro: 1.481 ± 0.028	0.759HisGln: 0.759 ± 0.018	1.347HisArg: 1.347 ± 0.024	1.242HisSer: 1.242 ± 0.024	1.267HisThr: 1.267 ± 0.027	1.562HisVal: 1.562 ± 0.029	0.429HisTrp: 0.429 ± 0.016	0.73HisTyr: 0.73 ± 0.018	0.0HisXaa: 0.0 ± 0.0
Ile	6.766IleAla: 6.766 ± 0.06	0.562IleCys: 0.562 ± 0.015	3.344IleAsp: 3.344 ± 0.044	2.943IleGlu: 2.943 ± 0.041	1.675IlePhe: 1.675 ± 0.031	4.344IleGly: 4.344 ± 0.047	1.181IleHis: 1.181 ± 0.024	2.141IleIle: 2.141 ± 0.035	1.583IleLys: 1.583 ± 0.032	4.669IleLeu: 4.669 ± 0.051	0.831IleMet: 0.831 ± 0.025	1.628IleAsn: 1.628 ± 0.032	2.822IlePro: 2.822 ± 0.037	1.741IleGln: 1.741 ± 0.024	2.796IleArg: 2.796 ± 0.037	3.173IleSer: 3.173 ± 0.043	3.141IleThr: 3.141 ± 0.045	4.101IleVal: 4.101 ± 0.044	0.675IleTrp: 0.675 ± 0.019	1.441IleTyr: 1.441 ± 0.026	0.0IleXaa: 0.0 ± 0.0
Lys	3.735LysAla: 3.735 ± 0.048	0.252LysCys: 0.252 ± 0.014	1.887LysAsp: 1.887 ± 0.028	1.625LysGlu: 1.625 ± 0.031	1.153LysPhe: 1.153 ± 0.025	2.24LysGly: 2.24 ± 0.04	0.809LysHis: 0.809 ± 0.02	2.161LysIle: 2.161 ± 0.033	1.385LysLys: 1.385 ± 0.029	3.001LysLeu: 3.001 ± 0.044	0.955LysMet: 0.955 ± 0.027	1.337LysAsn: 1.337 ± 0.03	2.124LysPro: 2.124 ± 0.034	1.347LysGln: 1.347 ± 0.027	2.172LysArg: 2.172 ± 0.033	2.303LysSer: 2.303 ± 0.037	2.455LysThr: 2.455 ± 0.035	2.07LysVal: 2.07 ± 0.036	0.457LysTrp: 0.457 ± 0.014	1.069LysTyr: 1.069 ± 0.024	0.0LysXaa: 0.0 ± 0.0
Leu	11.139LeuAla: 11.139 ± 0.079	1.05LeuCys: 1.05 ± 0.022	5.244LeuAsp: 5.244 ± 0.058	4.807LeuGlu: 4.807 ± 0.062	3.225LeuPhe: 3.225 ± 0.039	7.327LeuGly: 7.327 ± 0.059	1.967LeuHis: 1.967 ± 0.033	4.755LeuIle: 4.755 ± 0.056	3.269LeuLys: 3.269 ± 0.039	9.256LeuLeu: 9.256 ± 0.089	2.002LeuMet: 2.002 ± 0.04	2.863LeuAsn: 2.863 ± 0.037	5.241LeuPro: 5.241 ± 0.055	3.138LeuGln: 3.138 ± 0.038	6.493LeuArg: 6.493 ± 0.067	6.451LeuSer: 6.451 ± 0.061	6.496LeuThr: 6.496 ± 0.064	5.739LeuVal: 5.739 ± 0.054	1.414LeuTrp: 1.414 ± 0.032	2.449LeuTyr: 2.449 ± 0.032	0.0LeuXaa: 0.0 ± 0.0
Met	2.47MetAla: 2.47 ± 0.035	0.168MetCys: 0.168 ± 0.01	1.203MetAsp: 1.203 ± 0.023	1.151MetGlu: 1.151 ± 0.027	0.609MetPhe: 0.609 ± 0.015	1.587MetGly: 1.587 ± 0.025	0.46MetHis: 0.46 ± 0.015	1.17MetIle: 1.17 ± 0.024	0.933MetLys: 0.933 ± 0.022	2.124MetLeu: 2.124 ± 0.03	0.588MetMet: 0.588 ± 0.022	0.864MetAsn: 0.864 ± 0.017	1.21MetPro: 1.21 ± 0.026	0.87MetGln: 0.87 ± 0.02	1.557MetArg: 1.557 ± 0.029	1.481MetSer: 1.481 ± 0.028	1.716MetThr: 1.716 ± 0.028	1.25MetVal: 1.25 ± 0.026	0.24MetTrp: 0.24 ± 0.011	0.406MetTyr: 0.406 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	3.592AsnAla: 3.592 ± 0.047	0.324AsnCys: 0.324 ± 0.014	1.841AsnAsp: 1.841 ± 0.031	1.466AsnGlu: 1.466 ± 0.024	1.163AsnPhe: 1.163 ± 0.024	3.36AsnGly: 3.36 ± 0.058	0.752AsnHis: 0.752 ± 0.019	1.768AsnIle: 1.768 ± 0.029	0.973AsnLys: 0.973 ± 0.021	2.95AsnLeu: 2.95 ± 0.039	0.656AsnMet: 0.656 ± 0.017	1.326AsnAsn: 1.326 ± 0.03	2.176AsnPro: 2.176 ± 0.039	1.101AsnGln: 1.101 ± 0.023	1.604AsnArg: 1.604 ± 0.027	2.042AsnSer: 2.042 ± 0.033	2.058AsnThr: 2.058 ± 0.044	2.268AsnVal: 2.268 ± 0.036	0.552AsnTrp: 0.552 ± 0.017	1.092AsnTyr: 1.092 ± 0.029	0.0AsnXaa: 0.0 ± 0.0
Pro	6.548ProAla: 6.548 ± 0.075	0.367ProCys: 0.367 ± 0.014	3.447ProAsp: 3.447 ± 0.042	3.413ProGlu: 3.413 ± 0.043	1.808ProPhe: 1.808 ± 0.027	4.557ProGly: 4.557 ± 0.058	1.126ProHis: 1.126 ± 0.023	2.779ProIle: 2.779 ± 0.042	1.911ProLys: 1.911 ± 0.03	4.551ProLeu: 4.551 ± 0.049	1.218ProMet: 1.218 ± 0.024	1.97ProAsn: 1.97 ± 0.029	2.981ProPro: 2.981 ± 0.053	1.898ProGln: 1.898 ± 0.031	2.555ProArg: 2.555 ± 0.032	3.67ProSer: 3.67 ± 0.046	3.141ProThr: 3.141 ± 0.041	3.72ProVal: 3.72 ± 0.043	0.747ProTrp: 0.747 ± 0.018	1.588ProTyr: 1.588 ± 0.027	0.0ProXaa: 0.0 ± 0.0
Gln	4.003GlnAla: 4.003 ± 0.053	0.305GlnCys: 0.305 ± 0.013	1.916GlnAsp: 1.916 ± 0.03	1.904GlnGlu: 1.904 ± 0.033	1.31GlnPhe: 1.31 ± 0.022	2.638GlnGly: 2.638 ± 0.033	0.746GlnHis: 0.746 ± 0.021	2.402GlnIle: 2.402 ± 0.034	1.371GlnLys: 1.371 ± 0.029	2.866GlnLeu: 2.866 ± 0.032	1.03GlnMet: 1.03 ± 0.024	1.315GlnAsn: 1.315 ± 0.027	1.839GlnPro: 1.839 ± 0.029	1.579GlnGln: 1.579 ± 0.03	2.314GlnArg: 2.314 ± 0.033	2.507GlnSer: 2.507 ± 0.029	2.542GlnThr: 2.542 ± 0.034	2.303GlnVal: 2.303 ± 0.037	0.696GlnTrp: 0.696 ± 0.02	1.233GlnTyr: 1.233 ± 0.023	0.0GlnXaa: 0.0 ± 0.0
Arg	6.402ArgAla: 6.402 ± 0.059	0.541ArgCys: 0.541 ± 0.017	3.505ArgAsp: 3.505 ± 0.043	3.899ArgGlu: 3.899 ± 0.053	2.378ArgPhe: 2.378 ± 0.038	4.078ArgGly: 4.078 ± 0.049	1.479ArgHis: 1.479 ± 0.027	3.466ArgIle: 3.466 ± 0.04	2.205ArgLys: 2.205 ± 0.033	6.471ArgLeu: 6.471 ± 0.068	1.568ArgMet: 1.568 ± 0.032	1.754ArgAsn: 1.754 ± 0.031	2.89ArgPro: 2.89 ± 0.033	2.555ArgGln: 2.555 ± 0.04	4.982ArgArg: 4.982 ± 0.064	3.388ArgSer: 3.388 ± 0.045	3.295ArgThr: 3.295 ± 0.043	4.131ArgVal: 4.131 ± 0.048	1.031ArgTrp: 1.031 ± 0.023	1.876ArgTyr: 1.876 ± 0.031	0.0ArgXaa: 0.0 ± 0.0
Ser	6.91SerAla: 6.91 ± 0.073	0.561SerCys: 0.561 ± 0.017	3.683SerAsp: 3.683 ± 0.038	3.194SerGlu: 3.194 ± 0.046	2.098SerPhe: 2.098 ± 0.031	5.969SerGly: 5.969 ± 0.077	1.408SerHis: 1.408 ± 0.026	3.063SerIle: 3.063 ± 0.039	1.871SerLys: 1.871 ± 0.029	5.885SerLeu: 5.885 ± 0.048	1.24SerMet: 1.24 ± 0.023	2.039SerAsn: 2.039 ± 0.033	3.657SerPro: 3.657 ± 0.049	2.252SerGln: 2.252 ± 0.031	3.429SerArg: 3.429 ± 0.041	4.063SerSer: 4.063 ± 0.058	3.325SerThr: 3.325 ± 0.048	4.594SerVal: 4.594 ± 0.047	0.951SerTrp: 0.951 ± 0.023	1.904SerTyr: 1.904 ± 0.032	0.0SerXaa: 0.0 ± 0.0
Thr	6.369ThrAla: 6.369 ± 0.063	0.471ThrCys: 0.471 ± 0.015	3.48ThrAsp: 3.48 ± 0.046	2.825ThrGlu: 2.825 ± 0.039	2.219ThrPhe: 2.219 ± 0.035	5.215ThrGly: 5.215 ± 0.064	1.354ThrHis: 1.354 ± 0.026	3.395ThrIle: 3.395 ± 0.046	1.726ThrLys: 1.726 ± 0.033	6.488ThrLeu: 6.488 ± 0.061	1.19ThrMet: 1.19 ± 0.024	1.975ThrAsn: 1.975 ± 0.038	4.285ThrPro: 4.285 ± 0.054	2.343ThrGln: 2.343 ± 0.032	3.063ThrArg: 3.063 ± 0.039	3.488ThrSer: 3.488 ± 0.054	3.756ThrThr: 3.756 ± 0.061	4.672ThrVal: 4.672 ± 0.064	0.793ThrTrp: 0.793 ± 0.025	1.679ThrTyr: 1.679 ± 0.032	0.0ThrXaa: 0.0 ± 0.0
Val	7.524ValAla: 7.524 ± 0.065	0.755ValCys: 0.755 ± 0.017	3.811ValAsp: 3.811 ± 0.038	3.499ValGlu: 3.499 ± 0.05	2.543ValPhe: 2.543 ± 0.029	5.038ValGly: 5.038 ± 0.059	1.44ValHis: 1.44 ± 0.027	3.631ValIle: 3.631 ± 0.042	2.538ValLys: 2.538 ± 0.038	6.375ValLeu: 6.375 ± 0.058	1.463ValMet: 1.463 ± 0.027	2.466ValAsn: 2.466 ± 0.04	3.163ValPro: 3.163 ± 0.035	2.378ValGln: 2.378 ± 0.034	4.401ValArg: 4.401 ± 0.046	4.857ValSer: 4.857 ± 0.054	5.15ValThr: 5.15 ± 0.064	5.091ValVal: 5.091 ± 0.057	1.018ValTrp: 1.018 ± 0.023	1.965ValTyr: 1.965 ± 0.03	0.0ValXaa: 0.0 ± 0.0
Trp	1.357TrpAla: 1.357 ± 0.03	0.158TrpCys: 0.158 ± 0.009	0.959TrpAsp: 0.959 ± 0.026	0.805TrpGlu: 0.805 ± 0.019	0.541TrpPhe: 0.541 ± 0.018	1.132TrpGly: 1.132 ± 0.023	0.269TrpHis: 0.269 ± 0.012	0.809TrpIle: 0.809 ± 0.023	0.586TrpLys: 0.586 ± 0.017	1.472TrpLeu: 1.472 ± 0.028	0.403TrpMet: 0.403 ± 0.015	0.682TrpAsn: 0.682 ± 0.021	0.672TrpPro: 0.672 ± 0.018	0.503TrpGln: 0.503 ± 0.016	1.38TrpArg: 1.38 ± 0.03	1.126TrpSer: 1.126 ± 0.024	1.107TrpThr: 1.107 ± 0.029	0.853TrpVal: 0.853 ± 0.017	0.275TrpTrp: 0.275 ± 0.011	0.446TrpTyr: 0.446 ± 0.012	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.98TyrAla: 2.98 ± 0.039	0.334TyrCys: 0.334 ± 0.011	1.987TyrAsp: 1.987 ± 0.041	1.466TyrGlu: 1.466 ± 0.033	1.163TyrPhe: 1.163 ± 0.024	2.581TyrGly: 2.581 ± 0.037	0.772TyrHis: 0.772 ± 0.019	1.189TyrIle: 1.189 ± 0.022	0.862TyrLys: 0.862 ± 0.022	2.795TyrLeu: 2.795 ± 0.04	0.461TyrMet: 0.461 ± 0.014	1.06TyrAsn: 1.06 ± 0.027	1.532TyrPro: 1.532 ± 0.027	1.237TyrGln: 1.237 ± 0.025	1.933TyrArg: 1.933 ± 0.032	1.841TyrSer: 1.841 ± 0.036	1.754TyrThr: 1.754 ± 0.034	1.982TyrVal: 1.982 ± 0.033	0.537TyrTrp: 0.537 ± 0.015	1.096TyrTyr: 1.096 ± 0.028	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 6611 proteins (2208617 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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