Amino acid dipepetide frequency for Tortoise microvirus 6

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.14AlaAla: 4.14 ± 1.568
1.183AlaCys: 1.183 ± 1.189
4.14AlaAsp: 4.14 ± 1.235
2.365AlaGlu: 2.365 ± 0.859
2.365AlaPhe: 2.365 ± 0.877
2.365AlaGly: 2.365 ± 1.461
1.774AlaHis: 1.774 ± 0.86
3.548AlaIle: 3.548 ± 1.746
3.548AlaLys: 3.548 ± 1.683
6.505AlaLeu: 6.505 ± 1.344
1.183AlaMet: 1.183 ± 0.776
2.365AlaAsn: 2.365 ± 0.67
1.183AlaPro: 1.183 ± 0.849
5.322AlaGln: 5.322 ± 1.461
3.548AlaArg: 3.548 ± 1.32
5.914AlaSer: 5.914 ± 1.352
6.505AlaThr: 6.505 ± 1.308
2.957AlaVal: 2.957 ± 1.06
0.0AlaTrp: 0.0 ± 0.0
5.914AlaTyr: 5.914 ± 1.946
0.0AlaXaa: 0.0 ± 0.0
Cys
0.591CysAla: 0.591 ± 0.595
0.591CysCys: 0.591 ± 0.731
0.591CysAsp: 0.591 ± 0.424
1.183CysGlu: 1.183 ± 1.065
1.183CysPhe: 1.183 ± 0.869
0.591CysGly: 0.591 ± 0.595
1.183CysHis: 1.183 ± 0.894
0.591CysIle: 0.591 ± 0.424
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.591CysMet: 0.591 ± 0.684
1.183CysAsn: 1.183 ± 0.656
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
2.365CysArg: 2.365 ± 1.184
0.0CysSer: 0.0 ± 0.0
1.183CysThr: 1.183 ± 0.557
0.591CysVal: 0.591 ± 0.657
0.0CysTrp: 0.0 ± 0.0
0.591CysTyr: 0.591 ± 0.595
0.0CysXaa: 0.0 ± 0.0
Asp
2.957AspAla: 2.957 ± 1.169
0.591AspCys: 0.591 ± 0.424
4.731AspAsp: 4.731 ± 1.633
2.365AspGlu: 2.365 ± 1.245
2.957AspPhe: 2.957 ± 1.41
4.14AspGly: 4.14 ± 1.913
0.591AspHis: 0.591 ± 0.725
4.731AspIle: 4.731 ± 1.419
5.322AspLys: 5.322 ± 2.038
7.096AspLeu: 7.096 ± 1.566
3.548AspMet: 3.548 ± 1.843
4.14AspAsn: 4.14 ± 1.956
1.183AspPro: 1.183 ± 1.451
1.183AspGln: 1.183 ± 1.064
0.0AspArg: 0.0 ± 0.0
3.548AspSer: 3.548 ± 0.929
4.14AspThr: 4.14 ± 1.239
2.365AspVal: 2.365 ± 1.404
0.591AspTrp: 0.591 ± 0.532
6.505AspTyr: 6.505 ± 1.692
0.0AspXaa: 0.0 ± 0.0
Glu
2.957GluAla: 2.957 ± 1.402
0.0GluCys: 0.0 ± 0.0
1.774GluAsp: 1.774 ± 1.205
1.183GluGlu: 1.183 ± 1.189
1.774GluPhe: 1.774 ± 0.648
0.0GluGly: 0.0 ± 0.0
1.183GluHis: 1.183 ± 1.074
1.183GluIle: 1.183 ± 1.064
5.322GluLys: 5.322 ± 1.508
5.914GluLeu: 5.914 ± 1.678
1.183GluMet: 1.183 ± 1.447
4.731GluAsn: 4.731 ± 1.052
1.774GluPro: 1.774 ± 1.071
2.957GluGln: 2.957 ± 2.151
1.774GluArg: 1.774 ± 0.933
3.548GluSer: 3.548 ± 1.221
4.731GluThr: 4.731 ± 1.942
2.957GluVal: 2.957 ± 1.284
0.0GluTrp: 0.0 ± 0.0
2.957GluTyr: 2.957 ± 1.488
0.0GluXaa: 0.0 ± 0.0
Phe
3.548PheAla: 3.548 ± 1.46
0.0PheCys: 0.0 ± 0.0
4.731PheAsp: 4.731 ± 1.101
0.591PheGlu: 0.591 ± 0.684
2.365PhePhe: 2.365 ± 1.002
1.183PheGly: 1.183 ± 0.849
1.183PheHis: 1.183 ± 0.656
4.731PheIle: 4.731 ± 1.716
2.365PheLys: 2.365 ± 1.049
1.183PheLeu: 1.183 ± 0.73
1.183PheMet: 1.183 ± 0.849
3.548PheAsn: 3.548 ± 1.228
0.0PhePro: 0.0 ± 0.0
1.774PheGln: 1.774 ± 0.958
2.365PheArg: 2.365 ± 1.459
1.774PheSer: 1.774 ± 0.781
1.774PheThr: 1.774 ± 0.944
1.183PheVal: 1.183 ± 0.829
0.0PheTrp: 0.0 ± 0.0
2.365PheTyr: 2.365 ± 1.698
0.0PheXaa: 0.0 ± 0.0
Gly
1.774GlyAla: 1.774 ± 0.461
1.183GlyCys: 1.183 ± 0.894
3.548GlyAsp: 3.548 ± 0.942
1.774GlyGlu: 1.774 ± 0.461
0.591GlyPhe: 0.591 ± 0.424
3.548GlyGly: 3.548 ± 0.83
1.183GlyHis: 1.183 ± 0.849
2.957GlyIle: 2.957 ± 0.873
2.957GlyLys: 2.957 ± 1.171
7.096GlyLeu: 7.096 ± 1.793
0.591GlyMet: 0.591 ± 0.614
2.365GlyAsn: 2.365 ± 1.146
0.0GlyPro: 0.0 ± 0.0
4.14GlyGln: 4.14 ± 2.065
3.548GlyArg: 3.548 ± 1.934
4.14GlySer: 4.14 ± 0.973
2.957GlyThr: 2.957 ± 1.0
1.774GlyVal: 1.774 ± 0.951
0.591GlyTrp: 0.591 ± 0.657
3.548GlyTyr: 3.548 ± 1.566
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.591HisCys: 0.591 ± 0.595
1.774HisAsp: 1.774 ± 1.241
0.591HisGlu: 0.591 ± 0.684
1.183HisPhe: 1.183 ± 0.644
1.774HisGly: 1.774 ± 0.958
0.0HisHis: 0.0 ± 0.0
0.591HisIle: 0.591 ± 0.731
0.591HisLys: 0.591 ± 0.684
2.957HisLeu: 2.957 ± 1.06
0.0HisMet: 0.0 ± 0.0
2.365HisAsn: 2.365 ± 1.186
1.183HisPro: 1.183 ± 0.909
0.591HisGln: 0.591 ± 0.731
0.591HisArg: 0.591 ± 0.724
1.774HisSer: 1.774 ± 0.758
0.591HisThr: 0.591 ± 0.657
1.774HisVal: 1.774 ± 1.451
0.591HisTrp: 0.591 ± 0.424
1.774HisTyr: 1.774 ± 1.297
0.0HisXaa: 0.0 ± 0.0
Ile
5.322IleAla: 5.322 ± 1.133
0.591IleCys: 0.591 ± 0.657
7.096IleAsp: 7.096 ± 1.76
2.957IleGlu: 2.957 ± 2.548
1.774IlePhe: 1.774 ± 0.799
4.14IleGly: 4.14 ± 0.957
0.0IleHis: 0.0 ± 0.0
3.548IleIle: 3.548 ± 1.468
2.365IleLys: 2.365 ± 1.245
3.548IleLeu: 3.548 ± 1.861
2.365IleMet: 2.365 ± 1.154
1.183IleAsn: 1.183 ± 0.932
3.548IlePro: 3.548 ± 0.897
2.365IleGln: 2.365 ± 1.271
5.322IleArg: 5.322 ± 0.87
8.279IleSer: 8.279 ± 1.131
4.14IleThr: 4.14 ± 1.472
1.774IleVal: 1.774 ± 0.885
0.591IleTrp: 0.591 ± 0.424
3.548IleTyr: 3.548 ± 1.866
0.0IleXaa: 0.0 ± 0.0
Lys
4.14LysAla: 4.14 ± 1.94
0.0LysCys: 0.0 ± 0.0
5.322LysAsp: 5.322 ± 1.496
2.365LysGlu: 2.365 ± 1.429
0.591LysPhe: 0.591 ± 0.595
4.731LysGly: 4.731 ± 2.382
1.183LysHis: 1.183 ± 0.73
3.548LysIle: 3.548 ± 1.523
7.688LysLys: 7.688 ± 3.995
6.505LysLeu: 6.505 ± 2.078
4.731LysMet: 4.731 ± 1.621
4.14LysAsn: 4.14 ± 1.737
1.183LysPro: 1.183 ± 0.557
4.14LysGln: 4.14 ± 1.348
1.774LysArg: 1.774 ± 1.132
7.096LysSer: 7.096 ± 2.264
2.365LysThr: 2.365 ± 0.825
1.774LysVal: 1.774 ± 0.97
1.183LysTrp: 1.183 ± 0.673
2.957LysTyr: 2.957 ± 1.528
0.0LysXaa: 0.0 ± 0.0
Leu
2.957LeuAla: 2.957 ± 1.31
1.774LeuCys: 1.774 ± 0.784
4.731LeuAsp: 4.731 ± 1.129
5.914LeuGlu: 5.914 ± 2.12
2.957LeuPhe: 2.957 ± 1.49
6.505LeuGly: 6.505 ± 1.62
1.183LeuHis: 1.183 ± 1.004
3.548LeuIle: 3.548 ± 1.094
5.914LeuLys: 5.914 ± 2.056
5.914LeuLeu: 5.914 ± 1.748
1.183LeuMet: 1.183 ± 0.557
2.957LeuAsn: 2.957 ± 0.908
7.688LeuPro: 7.688 ± 2.864
4.731LeuGln: 4.731 ± 1.018
3.548LeuArg: 3.548 ± 1.663
11.236LeuSer: 11.236 ± 3.378
4.731LeuThr: 4.731 ± 1.352
4.731LeuVal: 4.731 ± 1.488
0.591LeuTrp: 0.591 ± 0.424
4.14LeuTyr: 4.14 ± 1.923
0.0LeuXaa: 0.0 ± 0.0
Met
2.957MetAla: 2.957 ± 0.999
0.0MetCys: 0.0 ± 0.0
1.183MetAsp: 1.183 ± 0.913
0.591MetGlu: 0.591 ± 0.725
1.774MetPhe: 1.774 ± 0.728
0.0MetGly: 0.0 ± 0.0
1.183MetHis: 1.183 ± 1.074
1.774MetIle: 1.774 ± 0.861
1.183MetLys: 1.183 ± 0.656
2.365MetLeu: 2.365 ± 0.953
1.774MetMet: 1.774 ± 0.792
1.774MetAsn: 1.774 ± 1.273
1.774MetPro: 1.774 ± 1.273
1.774MetGln: 1.774 ± 0.792
1.774MetArg: 1.774 ± 1.072
2.365MetSer: 2.365 ± 0.577
1.183MetThr: 1.183 ± 1.008
0.591MetVal: 0.591 ± 0.731
0.0MetTrp: 0.0 ± 0.0
1.183MetTyr: 1.183 ± 0.769
0.0MetXaa: 0.0 ± 0.0
Asn
2.957AsnAla: 2.957 ± 1.24
1.183AsnCys: 1.183 ± 0.96
2.365AsnAsp: 2.365 ± 1.246
4.14AsnGlu: 4.14 ± 1.345
2.957AsnPhe: 2.957 ± 1.542
2.957AsnGly: 2.957 ± 0.998
0.591AsnHis: 0.591 ± 0.614
2.957AsnIle: 2.957 ± 1.81
4.14AsnLys: 4.14 ± 1.136
2.365AsnLeu: 2.365 ± 1.198
0.0AsnMet: 0.0 ± 0.707
2.957AsnAsn: 2.957 ± 1.001
1.183AsnPro: 1.183 ± 0.557
1.183AsnGln: 1.183 ± 0.516
2.957AsnArg: 2.957 ± 1.653
3.548AsnSer: 3.548 ± 1.321
4.731AsnThr: 4.731 ± 1.291
2.365AsnVal: 2.365 ± 1.278
1.183AsnTrp: 1.183 ± 0.673
4.14AsnTyr: 4.14 ± 2.156
0.0AsnXaa: 0.0 ± 0.0
Pro
4.731ProAla: 4.731 ± 1.153
0.591ProCys: 0.591 ± 0.595
2.957ProAsp: 2.957 ± 1.125
2.365ProGlu: 2.365 ± 1.546
2.365ProPhe: 2.365 ± 1.142
0.591ProGly: 0.591 ± 0.424
1.183ProHis: 1.183 ± 0.911
4.14ProIle: 4.14 ± 1.146
0.0ProLys: 0.0 ± 0.0
4.14ProLeu: 4.14 ± 0.973
0.591ProMet: 0.591 ± 0.424
1.183ProAsn: 1.183 ± 0.849
0.591ProPro: 0.591 ± 0.424
2.365ProGln: 2.365 ± 1.027
1.183ProArg: 1.183 ± 0.557
2.957ProSer: 2.957 ± 1.158
3.548ProThr: 3.548 ± 2.547
2.365ProVal: 2.365 ± 0.859
0.0ProTrp: 0.0 ± 0.0
2.957ProTyr: 2.957 ± 0.873
0.0ProXaa: 0.0 ± 0.0
Gln
5.322GlnAla: 5.322 ± 2.15
0.0GlnCys: 0.0 ± 0.0
1.183GlnAsp: 1.183 ± 0.769
5.322GlnGlu: 5.322 ± 2.63
1.183GlnPhe: 1.183 ± 0.516
2.365GlnGly: 2.365 ± 1.258
0.591GlnHis: 0.591 ± 0.532
2.957GlnIle: 2.957 ± 2.051
4.14GlnLys: 4.14 ± 2.046
6.505GlnLeu: 6.505 ± 3.002
0.591GlnMet: 0.591 ± 0.532
4.14GlnAsn: 4.14 ± 1.352
2.365GlnPro: 2.365 ± 0.825
3.548GlnGln: 3.548 ± 0.787
4.731GlnArg: 4.731 ± 1.65
4.731GlnSer: 4.731 ± 1.787
5.322GlnThr: 5.322 ± 1.546
4.14GlnVal: 4.14 ± 1.486
0.591GlnTrp: 0.591 ± 0.731
1.774GlnTyr: 1.774 ± 1.369
0.0GlnXaa: 0.0 ± 0.0
Arg
2.365ArgAla: 2.365 ± 1.031
0.0ArgCys: 0.0 ± 0.0
2.957ArgAsp: 2.957 ± 1.162
2.957ArgGlu: 2.957 ± 1.444
0.591ArgPhe: 0.591 ± 0.731
1.774ArgGly: 1.774 ± 0.849
1.774ArgHis: 1.774 ± 1.14
4.14ArgIle: 4.14 ± 1.632
4.731ArgLys: 4.731 ± 1.814
2.957ArgLeu: 2.957 ± 1.65
2.365ArgMet: 2.365 ± 1.259
2.365ArgAsn: 2.365 ± 1.287
1.183ArgPro: 1.183 ± 0.557
4.14ArgGln: 4.14 ± 0.985
1.774ArgArg: 1.774 ± 1.403
2.365ArgSer: 2.365 ± 0.915
2.365ArgThr: 2.365 ± 1.033
1.183ArgVal: 1.183 ± 0.849
0.0ArgTrp: 0.0 ± 0.0
4.14ArgTyr: 4.14 ± 1.712
0.0ArgXaa: 0.0 ± 0.0
Ser
7.096SerAla: 7.096 ± 2.883
0.591SerCys: 0.591 ± 0.724
2.957SerAsp: 2.957 ± 0.921
3.548SerGlu: 3.548 ± 1.314
3.548SerPhe: 3.548 ± 2.114
4.14SerGly: 4.14 ± 0.889
0.591SerHis: 0.591 ± 0.424
6.505SerIle: 6.505 ± 1.782
5.322SerLys: 5.322 ± 1.149
7.096SerLeu: 7.096 ± 2.293
0.591SerMet: 0.591 ± 0.424
4.14SerAsn: 4.14 ± 1.724
4.14SerPro: 4.14 ± 1.359
7.096SerGln: 7.096 ± 1.978
2.957SerArg: 2.957 ± 0.991
5.322SerSer: 5.322 ± 2.745
7.688SerThr: 7.688 ± 1.989
4.14SerVal: 4.14 ± 0.973
0.0SerTrp: 0.0 ± 0.0
1.183SerTyr: 1.183 ± 0.849
0.0SerXaa: 0.0 ± 0.0
Thr
5.914ThrAla: 5.914 ± 1.48
0.591ThrCys: 0.591 ± 0.424
2.957ThrAsp: 2.957 ± 1.542
3.548ThrGlu: 3.548 ± 1.099
4.731ThrPhe: 4.731 ± 1.548
4.14ThrGly: 4.14 ± 1.142
1.183ThrHis: 1.183 ± 0.846
4.14ThrIle: 4.14 ± 1.903
4.731ThrLys: 4.731 ± 1.292
5.914ThrLeu: 5.914 ± 1.13
1.774ThrMet: 1.774 ± 0.849
1.774ThrAsn: 1.774 ± 1.01
3.548ThrPro: 3.548 ± 1.082
5.322ThrGln: 5.322 ± 2.15
1.774ThrArg: 1.774 ± 1.032
4.14ThrSer: 4.14 ± 1.113
2.957ThrThr: 2.957 ± 1.066
2.957ThrVal: 2.957 ± 0.795
2.365ThrTrp: 2.365 ± 0.79
2.957ThrTyr: 2.957 ± 1.329
0.0ThrXaa: 0.0 ± 0.0
Val
2.365ValAla: 2.365 ± 1.082
0.591ValCys: 0.591 ± 0.595
2.365ValAsp: 2.365 ± 0.877
1.774ValGlu: 1.774 ± 1.071
1.183ValPhe: 1.183 ± 1.461
1.774ValGly: 1.774 ± 0.792
1.774ValHis: 1.774 ± 0.728
2.365ValIle: 2.365 ± 0.953
1.774ValLys: 1.774 ± 0.948
4.14ValLeu: 4.14 ± 1.452
0.591ValMet: 0.591 ± 0.424
2.365ValAsn: 2.365 ± 1.641
3.548ValPro: 3.548 ± 1.692
3.548ValGln: 3.548 ± 1.621
1.774ValArg: 1.774 ± 0.849
2.957ValSer: 2.957 ± 1.204
3.548ValThr: 3.548 ± 1.286
2.957ValVal: 2.957 ± 1.568
0.0ValTrp: 0.0 ± 0.0
1.774ValTyr: 1.774 ± 0.799
0.0ValXaa: 0.0 ± 0.0
Trp
0.591TrpAla: 0.591 ± 0.532
0.591TrpCys: 0.591 ± 0.424
0.0TrpAsp: 0.0 ± 0.0
1.183TrpGlu: 1.183 ± 0.673
0.591TrpPhe: 0.591 ± 0.532
0.0TrpGly: 0.0 ± 0.0
0.591TrpHis: 0.591 ± 0.657
0.591TrpIle: 0.591 ± 0.424
0.591TrpLys: 0.591 ± 0.731
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.591TrpAsn: 0.591 ± 0.532
0.0TrpPro: 0.0 ± 0.0
1.183TrpGln: 1.183 ± 1.189
1.183TrpArg: 1.183 ± 0.769
0.0TrpSer: 0.0 ± 0.0
0.591TrpThr: 0.591 ± 0.424
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.14TyrAla: 4.14 ± 1.512
2.365TyrCys: 2.365 ± 1.513
5.322TyrAsp: 5.322 ± 1.572
1.183TyrGlu: 1.183 ± 0.769
1.183TyrPhe: 1.183 ± 0.849
3.548TyrGly: 3.548 ± 0.929
2.365TyrHis: 2.365 ± 1.912
5.914TyrIle: 5.914 ± 2.0
4.731TyrLys: 4.731 ± 1.423
4.731TyrLeu: 4.731 ± 1.877
1.774TyrMet: 1.774 ± 0.461
1.183TyrAsn: 1.183 ± 1.113
4.731TyrPro: 4.731 ± 1.487
4.14TyrGln: 4.14 ± 1.236
1.183TyrArg: 1.183 ± 0.516
2.957TyrSer: 2.957 ± 1.72
2.365TyrThr: 2.365 ± 1.031
0.591TyrVal: 0.591 ± 0.684
0.0TyrTrp: 0.0 ± 0.0
2.957TyrTyr: 2.957 ± 1.07
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 9 proteins (1692 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski