Treponema berlinense

Taxonomy: cellular organisms; Bacteria; Spirochaetes; Spirochaetia; Spirochaetales; Treponemataceae; Treponema

Average proteome isoelectric point is 6.47

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 2163 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A1T4QS80|A0A1T4QS80_9SPIO Uncharacterized protein OS=Treponema berlinense OX=225004 GN=SAMN02745152_02091 PE=4 SV=1
MM1 pKa = 7.75DD2 pKa = 3.83QPSSIKK8 pKa = 10.39LFKK11 pKa = 10.54EE12 pKa = 3.82NNICCVWDD20 pKa = 3.85EE21 pKa = 4.72EE22 pKa = 4.61NEE24 pKa = 3.82DD25 pKa = 3.81WYY27 pKa = 11.3FSIEE31 pKa = 4.25DD32 pKa = 4.68FILFLTDD39 pKa = 3.44CANSDD44 pKa = 3.68EE45 pKa = 4.97YY46 pKa = 10.84IEE48 pKa = 4.78EE49 pKa = 3.98MLSRR53 pKa = 11.84DD54 pKa = 3.27EE55 pKa = 4.86SLAFNWNTICVTVQMSGEE73 pKa = 3.97NEE75 pKa = 4.14QIHH78 pKa = 5.8EE79 pKa = 4.26VQAVNTQGLFRR90 pKa = 11.84IIQSIPP96 pKa = 2.92

Molecular weight: 11.26 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A1T4PYR6|A0A1T4PYR6_9SPIO Protein CcmA bactofilin family OS=Treponema berlinense OX=225004 GN=SAMN02745152_01780 PE=4 SV=1
MM1 pKa = 7.65RR2 pKa = 11.84LARR5 pKa = 11.84RR6 pKa = 11.84IRR8 pKa = 11.84PLRR11 pKa = 11.84WNKK14 pKa = 9.12TIRR17 pKa = 11.84ANSKK21 pKa = 10.01KK22 pKa = 9.21NSKK25 pKa = 9.72RR26 pKa = 11.84VRR28 pKa = 11.84TNHH31 pKa = 6.16EE32 pKa = 4.08LLKK35 pKa = 10.09TLAKK39 pKa = 10.45

Molecular weight: 4.76 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

2163

0

2163

748883

39

3781

346.2

38.8

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

7.258 ± 0.048

1.368 ± 0.025

5.414 ± 0.047

7.302 ± 0.058

5.279 ± 0.049

6.415 ± 0.048

1.396 ± 0.021

7.29 ± 0.046

8.247 ± 0.05

8.956 ± 0.053

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.213 ± 0.026

5.311 ± 0.04

3.379 ± 0.029

3.127 ± 0.032

3.7 ± 0.046

7.156 ± 0.066

5.328 ± 0.057

6.376 ± 0.045

0.921 ± 0.016

3.564 ± 0.037
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski