Amino acid dipepetide frequency for Apple chlorotic leaf spot virus (isolate apple) (ACLSV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.762AlaAla: 2.762 ± 1.555
0.789AlaCys: 0.789 ± 0.41
1.184AlaAsp: 1.184 ± 1.097
2.762AlaGlu: 2.762 ± 0.98
2.762AlaPhe: 2.762 ± 1.555
5.525AlaGly: 5.525 ± 2.599
1.184AlaHis: 1.184 ± 0.616
5.525AlaIle: 5.525 ± 1.945
6.709AlaLys: 6.709 ± 1.54
2.368AlaLeu: 2.368 ± 0.703
0.789AlaMet: 0.789 ± 0.483
3.157AlaAsn: 3.157 ± 0.425
1.184AlaPro: 1.184 ± 1.097
1.184AlaGln: 1.184 ± 0.769
3.946AlaArg: 3.946 ± 0.375
4.736AlaSer: 4.736 ± 1.405
1.973AlaThr: 1.973 ± 0.394
1.973AlaVal: 1.973 ± 1.388
0.0AlaTrp: 0.0 ± 0.0
1.579AlaTyr: 1.579 ± 0.821
0.0AlaXaa: 0.0 ± 0.0
Cys
0.395CysAla: 0.395 ± 0.205
0.0CysCys: 0.0 ± 0.0
0.395CysAsp: 0.395 ± 0.205
1.184CysGlu: 1.184 ± 0.769
1.579CysPhe: 1.579 ± 0.821
1.973CysGly: 1.973 ± 1.026
0.789CysHis: 0.789 ± 0.41
1.579CysIle: 1.579 ± 0.821
0.395CysLys: 0.395 ± 0.205
1.973CysLeu: 1.973 ± 1.026
0.395CysMet: 0.395 ± 0.205
0.0CysAsn: 0.0 ± 0.0
1.184CysPro: 1.184 ± 0.616
0.0CysGln: 0.0 ± 0.0
2.368CysArg: 2.368 ± 0.546
3.157CysSer: 3.157 ± 1.641
0.789CysThr: 0.789 ± 0.41
1.579CysVal: 1.579 ± 0.912
0.395CysTrp: 0.395 ± 0.205
0.789CysTyr: 0.789 ± 0.483
0.0CysXaa: 0.0 ± 0.0
Asp
3.157AspAla: 3.157 ± 0.425
0.789AspCys: 0.789 ± 0.41
5.13AspAsp: 5.13 ± 1.266
4.736AspGlu: 4.736 ± 1.709
3.157AspPhe: 3.157 ± 0.425
3.157AspGly: 3.157 ± 0.624
0.789AspHis: 0.789 ± 0.41
2.368AspIle: 2.368 ± 0.703
2.762AspLys: 2.762 ± 1.436
5.919AspLeu: 5.919 ± 1.1
1.184AspMet: 1.184 ± 0.616
2.762AspAsn: 2.762 ± 0.632
1.579AspPro: 1.579 ± 1.593
3.552AspGln: 3.552 ± 1.358
2.368AspArg: 2.368 ± 0.546
4.341AspSer: 4.341 ± 1.513
1.184AspThr: 1.184 ± 1.132
3.946AspVal: 3.946 ± 0.6
1.184AspTrp: 1.184 ± 0.616
2.368AspTyr: 2.368 ± 0.546
0.0AspXaa: 0.0 ± 0.0
Glu
5.919GluAla: 5.919 ± 2.843
1.973GluCys: 1.973 ± 1.026
3.157GluAsp: 3.157 ± 0.425
5.13GluGlu: 5.13 ± 2.667
5.525GluPhe: 5.525 ± 1.283
4.736GluGly: 4.736 ± 1.592
1.579GluHis: 1.579 ± 1.785
6.709GluIle: 6.709 ± 2.724
6.314GluLys: 6.314 ± 3.283
5.13GluLeu: 5.13 ± 1.123
0.789GluMet: 0.789 ± 0.41
4.341GluAsn: 4.341 ± 0.191
1.973GluPro: 1.973 ± 0.394
3.157GluGln: 3.157 ± 1.823
4.736GluArg: 4.736 ± 1.092
4.341GluSer: 4.341 ± 1.513
2.368GluThr: 2.368 ± 0.546
5.525GluVal: 5.525 ± 2.004
1.184GluTrp: 1.184 ± 0.616
0.395GluTyr: 0.395 ± 0.654
0.0GluXaa: 0.0 ± 0.0
Phe
5.13PheAla: 5.13 ± 2.136
1.973PheCys: 1.973 ± 1.026
5.13PheAsp: 5.13 ± 0.559
5.13PheGlu: 5.13 ± 1.984
1.184PhePhe: 1.184 ± 0.351
3.552PheGly: 3.552 ± 1.054
1.973PheHis: 1.973 ± 1.026
3.946PheIle: 3.946 ± 1.412
2.762PheLys: 2.762 ± 0.632
5.525PheLeu: 5.525 ± 1.283
2.368PheMet: 2.368 ± 1.174
3.552PheAsn: 3.552 ± 1.645
1.579PhePro: 1.579 ± 0.312
1.184PheGln: 1.184 ± 0.351
3.946PheArg: 3.946 ± 3.549
3.946PheSer: 3.946 ± 1.412
3.157PheThr: 3.157 ± 1.082
1.184PheVal: 1.184 ± 0.351
0.395PheTrp: 0.395 ± 0.205
0.789PheTyr: 0.789 ± 0.41
0.0PheXaa: 0.0 ± 0.0
Gly
3.157GlyAla: 3.157 ± 1.562
1.973GlyCys: 1.973 ± 1.026
4.341GlyAsp: 4.341 ± 0.933
3.946GlyGlu: 3.946 ± 1.307
3.946GlyPhe: 3.946 ± 0.974
4.736GlyGly: 4.736 ± 4.953
0.789GlyHis: 0.789 ± 1.309
2.762GlyIle: 2.762 ± 1.436
6.314GlyLys: 6.314 ± 0.927
6.314GlyLeu: 6.314 ± 2.045
0.789GlyMet: 0.789 ± 0.483
2.368GlyAsn: 2.368 ± 0.703
2.368GlyPro: 2.368 ± 0.546
1.184GlyGln: 1.184 ± 0.616
4.736GlyArg: 4.736 ± 2.432
7.893GlySer: 7.893 ± 1.82
2.368GlyThr: 2.368 ± 1.969
5.919GlyVal: 5.919 ± 0.225
1.973GlyTrp: 1.973 ± 0.394
1.579GlyTyr: 1.579 ± 0.821
0.0GlyXaa: 0.0 ± 0.0
His
0.789HisAla: 0.789 ± 0.41
0.0HisCys: 0.0 ± 0.0
1.184HisAsp: 1.184 ± 0.351
1.184HisGlu: 1.184 ± 0.351
1.184HisPhe: 1.184 ± 0.616
1.973HisGly: 1.973 ± 0.736
0.789HisHis: 0.789 ± 0.41
3.157HisIle: 3.157 ± 1.641
1.973HisLys: 1.973 ± 0.394
2.368HisLeu: 2.368 ± 0.546
0.395HisMet: 0.395 ± 0.205
0.789HisAsn: 0.789 ± 0.41
0.789HisPro: 0.789 ± 0.41
1.184HisGln: 1.184 ± 0.351
1.184HisArg: 1.184 ± 0.616
1.579HisSer: 1.579 ± 0.312
1.184HisThr: 1.184 ± 0.616
0.789HisVal: 0.789 ± 0.41
0.789HisTrp: 0.789 ± 1.309
0.395HisTyr: 0.395 ± 0.205
0.0HisXaa: 0.0 ± 0.0
Ile
2.762IleAla: 2.762 ± 1.765
1.579IleCys: 1.579 ± 0.821
2.762IleAsp: 2.762 ± 0.724
4.341IleGlu: 4.341 ± 2.257
3.157IlePhe: 3.157 ± 1.426
2.762IleGly: 2.762 ± 1.436
3.157IleHis: 3.157 ± 0.624
1.579IleIle: 1.579 ± 0.821
8.682IleLys: 8.682 ± 2.108
5.919IleLeu: 5.919 ± 2.349
1.579IleMet: 1.579 ± 0.734
1.184IleAsn: 1.184 ± 0.616
2.368IlePro: 2.368 ± 1.45
3.552IleGln: 3.552 ± 1.358
1.579IleArg: 1.579 ± 0.312
4.736IleSer: 4.736 ± 1.592
1.184IleThr: 1.184 ± 1.097
2.368IleVal: 2.368 ± 1.231
0.789IleTrp: 0.789 ± 0.41
3.552IleTyr: 3.552 ± 1.109
0.0IleXaa: 0.0 ± 0.0
Lys
5.919LysAla: 5.919 ± 1.1
1.184LysCys: 1.184 ± 0.616
4.736LysAsp: 4.736 ± 1.092
5.13LysGlu: 5.13 ± 1.964
2.762LysPhe: 2.762 ± 0.724
7.498LysGly: 7.498 ± 1.065
1.579LysHis: 1.579 ± 0.821
4.341LysIle: 4.341 ± 0.759
5.13LysLys: 5.13 ± 1.266
7.103LysLeu: 7.103 ± 1.289
2.762LysMet: 2.762 ± 0.942
3.157LysAsn: 3.157 ± 0.624
1.973LysPro: 1.973 ± 0.394
0.789LysGln: 0.789 ± 0.483
4.341LysArg: 4.341 ± 1.508
8.287LysSer: 8.287 ± 0.559
3.157LysThr: 3.157 ± 1.082
6.314LysVal: 6.314 ± 2.045
0.789LysTrp: 0.789 ± 0.41
1.973LysTyr: 1.973 ± 1.612
0.0LysXaa: 0.0 ± 0.0
Leu
6.709LeuAla: 6.709 ± 1.908
1.973LeuCys: 1.973 ± 0.756
4.341LeuAsp: 4.341 ± 0.191
6.314LeuGlu: 6.314 ± 0.927
5.919LeuPhe: 5.919 ± 0.225
5.919LeuGly: 5.919 ± 1.183
0.789LeuHis: 0.789 ± 0.854
3.552LeuIle: 3.552 ± 1.241
6.709LeuLys: 6.709 ± 2.712
6.314LeuLeu: 6.314 ± 1.709
3.157LeuMet: 3.157 ± 0.425
2.762LeuAsn: 2.762 ± 1.555
3.552LeuPro: 3.552 ± 1.109
3.552LeuGln: 3.552 ± 1.317
6.709LeuArg: 6.709 ± 1.29
8.682LeuSer: 8.682 ± 1.86
3.552LeuThr: 3.552 ± 1.847
4.736LeuVal: 4.736 ± 1.158
0.395LeuTrp: 0.395 ± 0.205
1.184LeuTyr: 1.184 ± 0.616
0.0LeuXaa: 0.0 ± 0.0
Met
0.789MetAla: 0.789 ± 0.854
1.579MetCys: 1.579 ± 0.312
1.973MetAsp: 1.973 ± 1.026
1.579MetGlu: 1.579 ± 0.734
2.368MetPhe: 2.368 ± 1.699
0.395MetGly: 0.395 ± 0.654
0.395MetHis: 0.395 ± 0.205
2.762MetIle: 2.762 ± 0.632
3.157MetLys: 3.157 ± 1.641
1.184MetLeu: 1.184 ± 0.351
1.184MetMet: 1.184 ± 1.132
1.579MetAsn: 1.579 ± 1.707
1.973MetPro: 1.973 ± 0.394
0.0MetGln: 0.0 ± 0.0
1.579MetArg: 1.579 ± 0.821
1.579MetSer: 1.579 ± 0.734
1.184MetThr: 1.184 ± 0.769
2.368MetVal: 2.368 ± 1.231
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.184AsnAla: 1.184 ± 1.132
1.184AsnCys: 1.184 ± 0.616
1.973AsnAsp: 1.973 ± 1.026
1.184AsnGlu: 1.184 ± 1.097
3.552AsnPhe: 3.552 ± 1.781
2.762AsnGly: 2.762 ± 0.942
1.579AsnHis: 1.579 ± 0.821
3.157AsnIle: 3.157 ± 1.823
3.946AsnLys: 3.946 ± 1.233
5.525AsnLeu: 5.525 ± 2.38
1.579AsnMet: 1.579 ± 2.019
0.395AsnAsn: 0.395 ± 0.205
0.395AsnPro: 0.395 ± 0.205
0.789AsnGln: 0.789 ± 0.41
2.762AsnArg: 2.762 ± 0.98
2.762AsnSer: 2.762 ± 0.632
0.395AsnThr: 0.395 ± 0.205
1.579AsnVal: 1.579 ± 0.821
0.395AsnTrp: 0.395 ± 0.205
3.157AsnTyr: 3.157 ± 0.624
0.0AsnXaa: 0.0 ± 0.0
Pro
0.0ProAla: 0.0 ± 0.0
1.184ProCys: 1.184 ± 0.616
1.973ProAsp: 1.973 ± 1.026
4.341ProGlu: 4.341 ± 2.43
1.973ProPhe: 1.973 ± 0.394
3.157ProGly: 3.157 ± 1.934
0.789ProHis: 0.789 ± 0.41
2.762ProIle: 2.762 ± 1.299
1.973ProLys: 1.973 ± 1.026
5.13ProLeu: 5.13 ± 0.282
0.789ProMet: 0.789 ± 0.41
1.579ProAsn: 1.579 ± 0.912
1.184ProPro: 1.184 ± 1.132
1.184ProGln: 1.184 ± 0.351
1.184ProArg: 1.184 ± 0.351
2.368ProSer: 2.368 ± 1.45
1.184ProThr: 1.184 ± 0.351
2.762ProVal: 2.762 ± 0.632
0.395ProTrp: 0.395 ± 0.205
1.184ProTyr: 1.184 ± 0.616
0.0ProXaa: 0.0 ± 0.0
Gln
2.368GlnAla: 2.368 ± 1.45
0.395GlnCys: 0.395 ± 0.205
2.368GlnAsp: 2.368 ± 2.264
2.762GlnGlu: 2.762 ± 1.436
1.184GlnPhe: 1.184 ± 0.351
1.973GlnGly: 1.973 ± 0.736
0.789GlnHis: 0.789 ± 0.483
1.579GlnIle: 1.579 ± 0.821
3.157GlnLys: 3.157 ± 1.823
2.368GlnLeu: 2.368 ± 0.829
0.0GlnMet: 0.0 ± 0.0
1.973GlnAsn: 1.973 ± 0.394
0.395GlnPro: 0.395 ± 0.205
0.789GlnGln: 0.789 ± 0.854
1.973GlnArg: 1.973 ± 0.394
1.973GlnSer: 1.973 ± 0.394
3.157GlnThr: 3.157 ± 2.925
3.157GlnVal: 3.157 ± 0.425
0.0GlnTrp: 0.0 ± 0.0
0.395GlnTyr: 0.395 ± 0.205
0.0GlnXaa: 0.0 ± 0.0
Arg
1.579ArgAla: 1.579 ± 0.312
0.395ArgCys: 0.395 ± 0.205
1.579ArgAsp: 1.579 ± 0.821
5.919ArgGlu: 5.919 ± 1.24
5.13ArgPhe: 5.13 ± 0.983
4.341ArgGly: 4.341 ± 1.513
1.579ArgHis: 1.579 ± 0.821
0.789ArgIle: 0.789 ± 0.483
5.13ArgLys: 5.13 ± 1.984
7.103ArgLeu: 7.103 ± 2.109
2.368ArgMet: 2.368 ± 1.231
1.973ArgAsn: 1.973 ± 0.736
1.973ArgPro: 1.973 ± 0.736
3.552ArgGln: 3.552 ± 0.574
5.525ArgArg: 5.525 ± 1.21
4.341ArgSer: 4.341 ± 0.933
1.973ArgThr: 1.973 ± 0.756
3.552ArgVal: 3.552 ± 1.781
0.395ArgTrp: 0.395 ± 0.654
1.973ArgTyr: 1.973 ± 1.026
0.0ArgXaa: 0.0 ± 0.0
Ser
3.552SerAla: 3.552 ± 1.781
1.184SerCys: 1.184 ± 0.351
7.103SerAsp: 7.103 ± 0.577
7.893SerGlu: 7.893 ± 2.311
3.946SerPhe: 3.946 ± 1.156
5.13SerGly: 5.13 ± 1.984
1.973SerHis: 1.973 ± 1.026
4.736SerIle: 4.736 ± 2.118
4.341SerLys: 4.341 ± 2.257
4.736SerLeu: 4.736 ± 1.092
3.157SerMet: 3.157 ± 1.469
4.341SerAsn: 4.341 ± 0.93
2.368SerPro: 2.368 ± 0.703
3.552SerGln: 3.552 ± 1.109
4.341SerArg: 4.341 ± 1.513
8.287SerSer: 8.287 ± 1.397
3.552SerThr: 3.552 ± 0.574
5.525SerVal: 5.525 ± 1.21
0.789SerTrp: 0.789 ± 0.483
4.341SerTyr: 4.341 ± 1.508
0.0SerXaa: 0.0 ± 0.0
Thr
1.184ThrAla: 1.184 ± 0.616
0.395ThrCys: 0.395 ± 0.205
1.973ThrAsp: 1.973 ± 1.388
3.157ThrGlu: 3.157 ± 1.426
3.946ThrPhe: 3.946 ± 0.6
3.157ThrGly: 3.157 ± 0.776
0.789ThrHis: 0.789 ± 0.41
1.973ThrIle: 1.973 ± 1.026
1.579ThrLys: 1.579 ± 0.821
3.946ThrLeu: 3.946 ± 0.6
0.395ThrMet: 0.395 ± 0.205
1.973ThrAsn: 1.973 ± 2.385
2.368ThrPro: 2.368 ± 0.581
0.789ThrGln: 0.789 ± 0.483
2.368ThrArg: 2.368 ± 1.231
2.762ThrSer: 2.762 ± 2.007
1.973ThrThr: 1.973 ± 2.671
1.973ThrVal: 1.973 ± 0.394
0.0ThrTrp: 0.0 ± 0.0
0.395ThrTyr: 0.395 ± 0.205
0.0ThrXaa: 0.0 ± 0.0
Val
3.946ValAla: 3.946 ± 0.789
1.579ValCys: 1.579 ± 0.734
2.762ValAsp: 2.762 ± 0.466
5.525ValGlu: 5.525 ± 1.315
2.762ValPhe: 2.762 ± 0.466
3.552ValGly: 3.552 ± 2.398
1.579ValHis: 1.579 ± 0.312
4.341ValIle: 4.341 ± 0.191
4.736ValLys: 4.736 ± 1.664
3.946ValLeu: 3.946 ± 1.233
2.762ValMet: 2.762 ± 1.204
1.579ValAsn: 1.579 ± 0.821
4.736ValPro: 4.736 ± 1.405
1.579ValGln: 1.579 ± 0.312
2.762ValArg: 2.762 ± 0.724
3.946ValSer: 3.946 ± 1.64
1.579ValThr: 1.579 ± 0.912
1.579ValVal: 1.579 ± 1.707
0.395ValTrp: 0.395 ± 0.205
2.368ValTyr: 2.368 ± 0.546
0.0ValXaa: 0.0 ± 0.0
Trp
0.395TrpAla: 0.395 ± 0.205
0.789TrpCys: 0.789 ± 0.483
0.395TrpAsp: 0.395 ± 0.205
0.789TrpGlu: 0.789 ± 0.483
0.789TrpPhe: 0.789 ± 0.41
1.579TrpGly: 1.579 ± 0.312
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.789TrpLys: 0.789 ± 0.483
1.184TrpLeu: 1.184 ± 0.616
0.0TrpMet: 0.0 ± 0.0
0.395TrpAsn: 0.395 ± 0.654
0.395TrpPro: 0.395 ± 0.205
0.0TrpGln: 0.0 ± 0.0
1.184TrpArg: 1.184 ± 0.616
1.579TrpSer: 1.579 ± 0.821
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.395TrpTyr: 0.395 ± 0.205
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.395TyrAla: 0.395 ± 0.205
0.0TyrCys: 0.0 ± 0.0
1.973TyrAsp: 1.973 ± 0.394
1.973TyrGlu: 1.973 ± 1.026
1.579TyrPhe: 1.579 ± 0.821
1.579TyrGly: 1.579 ± 0.821
0.789TyrHis: 0.789 ± 0.41
1.973TyrIle: 1.973 ± 0.82
2.368TyrLys: 2.368 ± 0.581
2.762TyrLeu: 2.762 ± 1.436
0.789TyrMet: 0.789 ± 0.41
0.395TyrAsn: 0.395 ± 0.205
2.762TyrPro: 2.762 ± 0.466
1.184TyrGln: 1.184 ± 0.616
1.579TyrArg: 1.579 ± 0.821
3.552TyrSer: 3.552 ± 1.109
1.184TyrThr: 1.184 ± 0.616
1.579TyrVal: 1.579 ± 0.967
0.395TyrTrp: 0.395 ± 0.205
0.395TyrTyr: 0.395 ± 0.205
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (2535 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski