Amino acid dipepetide frequency for Botrytis virus F (isolate Botrytis cinerea/New Zealand/Howitt/2001) (BotV-F)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
12.745AlaAla: 12.745 ± 1.672
0.91AlaCys: 0.91 ± 0.396
3.641AlaAsp: 3.641 ± 1.586
5.007AlaGlu: 5.007 ± 0.709
5.007AlaPhe: 5.007 ± 0.736
3.186AlaGly: 3.186 ± 1.501
1.821AlaHis: 1.821 ± 0.652
5.917AlaIle: 5.917 ± 1.757
4.096AlaLys: 4.096 ± 2.55
8.648AlaLeu: 8.648 ± 3.767
0.455AlaMet: 0.455 ± 1.246
3.641AlaAsn: 3.641 ± 1.303
8.193AlaPro: 8.193 ± 5.099
4.096AlaGln: 4.096 ± 1.105
6.827AlaArg: 6.827 ± 2.805
8.193AlaSer: 8.193 ± 0.679
8.648AlaThr: 8.648 ± 0.877
5.007AlaVal: 5.007 ± 2.181
0.91AlaTrp: 0.91 ± 0.396
5.007AlaTyr: 5.007 ± 0.736
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.455CysCys: 0.455 ± 0.198
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.455CysPhe: 0.455 ± 0.198
1.365CysGly: 1.365 ± 0.595
0.0CysHis: 0.0 ± 0.0
0.91CysIle: 0.91 ± 1.048
0.0CysLys: 0.0 ± 0.0
1.365CysLeu: 1.365 ± 0.595
0.455CysMet: 0.455 ± 0.198
0.455CysAsn: 0.455 ± 0.198
1.365CysPro: 1.365 ± 0.595
0.91CysGln: 0.91 ± 0.396
0.91CysArg: 0.91 ± 0.396
0.0CysSer: 0.0 ± 0.0
0.455CysThr: 0.455 ± 0.198
0.0CysVal: 0.0 ± 0.0
0.455CysTrp: 0.455 ± 0.198
0.91CysTyr: 0.91 ± 0.396
0.0CysXaa: 0.0 ± 0.0
Asp
7.738AspAla: 7.738 ± 0.964
0.455AspCys: 0.455 ± 0.198
3.641AspAsp: 3.641 ± 1.586
2.276AspGlu: 2.276 ± 0.991
3.641AspPhe: 3.641 ± 0.141
2.731AspGly: 2.731 ± 0.255
2.731AspHis: 2.731 ± 1.189
1.821AspIle: 1.821 ± 0.652
3.186AspLys: 3.186 ± 0.057
4.096AspLeu: 4.096 ± 0.34
1.365AspMet: 1.365 ± 0.715
3.186AspAsn: 3.186 ± 1.388
3.186AspPro: 3.186 ± 1.388
0.91AspGln: 0.91 ± 0.396
5.007AspArg: 5.007 ± 0.736
3.186AspSer: 3.186 ± 0.057
2.276AspThr: 2.276 ± 0.991
1.821AspVal: 1.821 ± 0.793
0.91AspTrp: 0.91 ± 0.396
1.821AspTyr: 1.821 ± 0.793
0.0AspXaa: 0.0 ± 0.0
Glu
4.096GluAla: 4.096 ± 0.34
0.455GluCys: 0.455 ± 0.198
2.276GluAsp: 2.276 ± 0.991
3.186GluGlu: 3.186 ± 0.057
0.91GluPhe: 0.91 ± 1.048
0.91GluGly: 0.91 ± 0.396
2.276GluHis: 2.276 ± 0.991
0.91GluIle: 0.91 ± 0.396
1.821GluLys: 1.821 ± 0.793
4.552GluLeu: 4.552 ± 2.351
0.91GluMet: 0.91 ± 0.396
1.821GluAsn: 1.821 ± 0.652
5.007GluPro: 5.007 ± 2.181
1.365GluGln: 1.365 ± 0.85
2.276GluArg: 2.276 ± 0.991
3.641GluSer: 3.641 ± 1.303
5.007GluThr: 5.007 ± 0.709
3.186GluVal: 3.186 ± 1.388
0.0GluTrp: 0.0 ± 0.0
2.276GluTyr: 2.276 ± 0.991
0.0GluXaa: 0.0 ± 0.0
Phe
4.552PheAla: 4.552 ± 2.351
0.91PheCys: 0.91 ± 0.396
2.731PheAsp: 2.731 ± 3.144
2.276PheGlu: 2.276 ± 0.453
0.91PhePhe: 0.91 ± 0.396
2.276PheGly: 2.276 ± 0.991
2.276PheHis: 2.276 ± 1.898
0.91PheIle: 0.91 ± 0.396
1.365PheLys: 1.365 ± 0.85
2.731PheLeu: 2.731 ± 0.255
0.91PheMet: 0.91 ± 0.396
2.276PheAsn: 2.276 ± 0.453
2.276PhePro: 2.276 ± 0.991
0.455PheGln: 0.455 ± 0.198
2.731PheArg: 2.731 ± 0.255
1.821PheSer: 1.821 ± 0.793
1.821PheThr: 1.821 ± 0.793
1.821PheVal: 1.821 ± 0.793
1.365PheTrp: 1.365 ± 0.595
0.91PheTyr: 0.91 ± 0.396
0.0PheXaa: 0.0 ± 0.0
Gly
2.731GlyAla: 2.731 ± 1.7
0.0GlyCys: 0.0 ± 0.0
3.186GlyAsp: 3.186 ± 0.057
2.731GlyGlu: 2.731 ± 1.189
1.821GlyPhe: 1.821 ± 3.541
3.641GlyGly: 3.641 ± 0.141
0.0GlyHis: 0.0 ± 0.0
1.821GlyIle: 1.821 ± 0.652
4.096GlyLys: 4.096 ± 1.105
5.007GlyLeu: 5.007 ± 0.736
1.365GlyMet: 1.365 ± 3.739
3.641GlyAsn: 3.641 ± 0.141
3.641GlyPro: 3.641 ± 1.586
3.641GlyGln: 3.641 ± 4.192
0.91GlyArg: 0.91 ± 0.396
4.096GlySer: 4.096 ± 2.55
4.096GlyThr: 4.096 ± 1.105
0.455GlyVal: 0.455 ± 0.198
1.821GlyTrp: 1.821 ± 0.793
1.365GlyTyr: 1.365 ± 0.595
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.91HisCys: 0.91 ± 0.396
2.276HisAsp: 2.276 ± 0.453
0.91HisGlu: 0.91 ± 0.396
1.365HisPhe: 1.365 ± 0.595
1.821HisGly: 1.821 ± 0.652
0.91HisHis: 0.91 ± 0.396
0.455HisIle: 0.455 ± 0.198
1.821HisLys: 1.821 ± 2.096
2.731HisLeu: 2.731 ± 1.189
0.455HisMet: 0.455 ± 0.198
0.455HisAsn: 0.455 ± 0.198
1.821HisPro: 1.821 ± 0.793
0.455HisGln: 0.455 ± 0.198
2.731HisArg: 2.731 ± 0.255
4.096HisSer: 4.096 ± 2.55
0.455HisThr: 0.455 ± 0.198
2.276HisVal: 2.276 ± 0.453
1.365HisTrp: 1.365 ± 0.595
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
5.007IleAla: 5.007 ± 0.709
0.455IleCys: 0.455 ± 0.198
2.731IleAsp: 2.731 ± 0.255
2.276IleGlu: 2.276 ± 0.453
1.365IlePhe: 1.365 ± 0.595
1.365IleGly: 1.365 ± 0.85
2.276IleHis: 2.276 ± 0.991
1.821IleIle: 1.821 ± 3.541
3.186IleLys: 3.186 ± 0.057
2.731IleLeu: 2.731 ± 1.7
0.455IleMet: 0.455 ± 0.198
1.821IleAsn: 1.821 ± 0.793
5.007IlePro: 5.007 ± 0.709
0.455IleGln: 0.455 ± 1.246
2.276IleArg: 2.276 ± 0.991
1.365IleSer: 1.365 ± 0.595
3.641IleThr: 3.641 ± 0.141
2.276IleVal: 2.276 ± 0.991
0.91IleTrp: 0.91 ± 0.396
0.91IleTyr: 0.91 ± 0.396
0.0IleXaa: 0.0 ± 0.0
Lys
3.641LysAla: 3.641 ± 1.586
0.455LysCys: 0.455 ± 0.198
4.096LysAsp: 4.096 ± 1.784
0.91LysGlu: 0.91 ± 0.396
1.365LysPhe: 1.365 ± 0.85
1.821LysGly: 1.821 ± 2.096
0.0LysHis: 0.0 ± 0.0
1.365LysIle: 1.365 ± 0.595
1.821LysLys: 1.821 ± 0.652
5.917LysLeu: 5.917 ± 1.133
2.731LysMet: 2.731 ± 0.4
0.455LysAsn: 0.455 ± 0.198
2.731LysPro: 2.731 ± 1.7
1.365LysGln: 1.365 ± 0.85
3.186LysArg: 3.186 ± 0.057
3.186LysSer: 3.186 ± 2.946
2.276LysThr: 2.276 ± 0.453
2.731LysVal: 2.731 ± 0.255
0.0LysTrp: 0.0 ± 0.0
2.276LysTyr: 2.276 ± 0.453
0.0LysXaa: 0.0 ± 0.0
Leu
10.924LeuAla: 10.924 ± 1.021
0.91LeuCys: 0.91 ± 0.396
5.917LeuAsp: 5.917 ± 1.133
4.096LeuGlu: 4.096 ± 0.34
3.641LeuPhe: 3.641 ± 1.586
3.641LeuGly: 3.641 ± 1.303
2.276LeuHis: 2.276 ± 0.453
1.821LeuIle: 1.821 ± 0.652
5.007LeuLys: 5.007 ± 0.736
8.648LeuLeu: 8.648 ± 2.322
1.365LeuMet: 1.365 ± 0.595
4.096LeuAsn: 4.096 ± 1.784
10.924LeuPro: 10.924 ± 3.313
2.731LeuGln: 2.731 ± 0.255
5.007LeuArg: 5.007 ± 0.736
6.372LeuSer: 6.372 ± 1.331
5.462LeuThr: 5.462 ± 0.51
6.827LeuVal: 6.827 ± 1.529
1.821LeuTrp: 1.821 ± 0.793
1.821LeuTyr: 1.821 ± 0.652
0.0LeuXaa: 0.0 ± 0.0
Met
0.91MetAla: 0.91 ± 0.396
0.455MetCys: 0.455 ± 0.198
0.91MetAsp: 0.91 ± 1.048
0.0MetGlu: 0.0 ± 0.0
0.91MetPhe: 0.91 ± 1.048
0.91MetGly: 0.91 ± 1.048
1.365MetHis: 1.365 ± 0.595
0.91MetIle: 0.91 ± 1.048
1.365MetLys: 1.365 ± 0.595
1.821MetLeu: 1.821 ± 0.652
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.455MetPro: 0.455 ± 0.198
0.455MetGln: 0.455 ± 0.198
1.821MetArg: 1.821 ± 0.793
0.91MetSer: 0.91 ± 0.396
2.276MetThr: 2.276 ± 0.453
2.276MetVal: 2.276 ± 0.453
0.0MetTrp: 0.0 ± 0.0
0.455MetTyr: 0.455 ± 0.198
0.0MetXaa: 0.0 ± 0.0
Asn
3.641AsnAla: 3.641 ± 1.303
0.0AsnCys: 0.0 ± 0.0
4.096AsnAsp: 4.096 ± 0.34
2.276AsnGlu: 2.276 ± 0.991
2.276AsnPhe: 2.276 ± 0.453
1.365AsnGly: 1.365 ± 0.595
0.0AsnHis: 0.0 ± 0.0
2.276AsnIle: 2.276 ± 0.453
1.821AsnLys: 1.821 ± 0.793
1.821AsnLeu: 1.821 ± 0.652
0.91AsnMet: 0.91 ± 1.048
1.365AsnAsn: 1.365 ± 0.595
5.007AsnPro: 5.007 ± 0.736
1.821AsnGln: 1.821 ± 0.652
2.276AsnArg: 2.276 ± 0.991
2.276AsnSer: 2.276 ± 0.991
2.276AsnThr: 2.276 ± 0.991
1.365AsnVal: 1.365 ± 0.595
0.455AsnTrp: 0.455 ± 0.198
0.91AsnTyr: 0.91 ± 0.396
0.0AsnXaa: 0.0 ± 0.0
Pro
9.558ProAla: 9.558 ± 3.06
0.0ProCys: 0.0 ± 0.0
4.552ProAsp: 4.552 ± 1.982
5.462ProGlu: 5.462 ± 0.934
1.365ProPhe: 1.365 ± 0.595
5.462ProGly: 5.462 ± 0.51
2.276ProHis: 2.276 ± 1.898
3.186ProIle: 3.186 ± 0.057
1.821ProLys: 1.821 ± 0.652
9.558ProLeu: 9.558 ± 2.719
0.0ProMet: 0.0 ± 0.0
1.821ProAsn: 1.821 ± 0.793
11.834ProPro: 11.834 ± 4.958
3.186ProGln: 3.186 ± 1.501
5.007ProArg: 5.007 ± 2.153
9.558ProSer: 9.558 ± 0.171
8.193ProThr: 8.193 ± 2.124
3.186ProVal: 3.186 ± 1.501
0.0ProTrp: 0.0 ± 0.0
2.731ProTyr: 2.731 ± 0.255
0.455ProXaa: 0.455 ± 0.198
Gln
2.276GlnAla: 2.276 ± 0.991
0.0GlnCys: 0.0 ± 0.0
0.91GlnAsp: 0.91 ± 0.396
1.365GlnGlu: 1.365 ± 0.595
0.91GlnPhe: 0.91 ± 1.048
1.821GlnGly: 1.821 ± 0.652
0.0GlnHis: 0.0 ± 0.0
1.365GlnIle: 1.365 ± 0.85
0.91GlnLys: 0.91 ± 1.048
4.552GlnLeu: 4.552 ± 0.538
3.641GlnMet: 3.641 ± 0.141
0.455GlnAsn: 0.455 ± 1.246
2.731GlnPro: 2.731 ± 1.7
1.365GlnGln: 1.365 ± 2.294
2.731GlnArg: 2.731 ± 1.189
3.641GlnSer: 3.641 ± 2.748
4.552GlnThr: 4.552 ± 3.796
2.276GlnVal: 2.276 ± 0.453
0.455GlnTrp: 0.455 ± 0.198
1.365GlnTyr: 1.365 ± 0.595
0.0GlnXaa: 0.0 ± 0.0
Arg
8.193ArgAla: 8.193 ± 2.21
1.365ArgCys: 1.365 ± 0.595
3.186ArgAsp: 3.186 ± 1.388
2.276ArgGlu: 2.276 ± 3.343
4.096ArgPhe: 4.096 ± 1.105
2.731ArgGly: 2.731 ± 1.189
0.455ArgHis: 0.455 ± 0.198
3.641ArgIle: 3.641 ± 1.586
1.365ArgLys: 1.365 ± 0.595
6.827ArgLeu: 6.827 ± 2.974
0.0ArgMet: 0.0 ± 0.0
4.096ArgAsn: 4.096 ± 0.34
4.552ArgPro: 4.552 ± 2.351
3.641ArgGln: 3.641 ± 0.141
5.462ArgArg: 5.462 ± 0.934
2.731ArgSer: 2.731 ± 1.189
4.096ArgThr: 4.096 ± 1.784
1.365ArgVal: 1.365 ± 0.595
0.455ArgTrp: 0.455 ± 0.198
4.552ArgTyr: 4.552 ± 1.982
0.0ArgXaa: 0.0 ± 0.0
Ser
4.096SerAla: 4.096 ± 2.55
1.365SerCys: 1.365 ± 0.595
3.641SerAsp: 3.641 ± 1.586
2.731SerGlu: 2.731 ± 0.255
1.365SerPhe: 1.365 ± 0.595
4.096SerGly: 4.096 ± 5.439
4.096SerHis: 4.096 ± 2.55
3.641SerIle: 3.641 ± 1.586
3.641SerLys: 3.641 ± 0.141
4.552SerLeu: 4.552 ± 0.907
0.455SerMet: 0.455 ± 0.198
2.276SerAsn: 2.276 ± 0.991
5.007SerPro: 5.007 ± 0.709
4.096SerGln: 4.096 ± 0.34
4.552SerArg: 4.552 ± 0.538
5.007SerSer: 5.007 ± 3.598
5.462SerThr: 5.462 ± 1.955
5.462SerVal: 5.462 ± 0.934
2.276SerTrp: 2.276 ± 0.991
2.276SerTyr: 2.276 ± 0.453
0.0SerXaa: 0.0 ± 0.0
Thr
7.738ThrAla: 7.738 ± 0.481
0.455ThrCys: 0.455 ± 0.198
2.731ThrAsp: 2.731 ± 1.189
3.186ThrGlu: 3.186 ± 1.388
3.186ThrPhe: 3.186 ± 0.057
3.641ThrGly: 3.641 ± 1.303
0.91ThrHis: 0.91 ± 0.396
3.186ThrIle: 3.186 ± 0.057
1.821ThrLys: 1.821 ± 0.793
7.738ThrLeu: 7.738 ± 2.408
0.91ThrMet: 0.91 ± 0.396
1.365ThrAsn: 1.365 ± 0.85
7.738ThrPro: 7.738 ± 3.853
2.731ThrGln: 2.731 ± 1.189
5.007ThrArg: 5.007 ± 2.181
5.462ThrSer: 5.462 ± 1.955
4.552ThrThr: 4.552 ± 2.351
5.007ThrVal: 5.007 ± 2.181
0.455ThrTrp: 0.455 ± 0.198
3.186ThrTyr: 3.186 ± 1.388
0.0ThrXaa: 0.0 ± 0.0
Val
5.462ValAla: 5.462 ± 2.379
0.455ValCys: 0.455 ± 1.246
3.186ValAsp: 3.186 ± 1.388
2.731ValGlu: 2.731 ± 1.189
0.91ValPhe: 0.91 ± 0.396
3.186ValGly: 3.186 ± 1.501
1.365ValHis: 1.365 ± 0.595
3.641ValIle: 3.641 ± 1.586
2.731ValLys: 2.731 ± 0.255
4.552ValLeu: 4.552 ± 1.982
0.0ValMet: 0.0 ± 0.0
3.186ValAsn: 3.186 ± 0.057
5.007ValPro: 5.007 ± 2.181
2.276ValGln: 2.276 ± 1.898
3.186ValArg: 3.186 ± 0.057
1.365ValSer: 1.365 ± 0.595
2.731ValThr: 2.731 ± 1.189
1.365ValVal: 1.365 ± 0.595
0.91ValTrp: 0.91 ± 0.396
2.276ValTyr: 2.276 ± 0.991
0.0ValXaa: 0.0 ± 0.0
Trp
0.91TrpAla: 0.91 ± 0.396
0.0TrpCys: 0.0 ± 0.0
0.91TrpAsp: 0.91 ± 0.396
0.455TrpGlu: 0.455 ± 0.198
1.365TrpPhe: 1.365 ± 0.595
1.365TrpGly: 1.365 ± 0.595
0.91TrpHis: 0.91 ± 0.396
0.455TrpIle: 0.455 ± 0.198
0.0TrpLys: 0.0 ± 0.0
0.91TrpLeu: 0.91 ± 0.396
0.91TrpMet: 0.91 ± 0.396
0.455TrpAsn: 0.455 ± 0.198
0.455TrpPro: 0.455 ± 0.198
0.0TrpGln: 0.0 ± 0.0
0.91TrpArg: 0.91 ± 0.396
1.365TrpSer: 1.365 ± 0.595
0.91TrpThr: 0.91 ± 0.396
0.91TrpVal: 0.91 ± 0.396
0.0TrpTrp: 0.0 ± 0.0
1.365TrpTyr: 1.365 ± 0.595
0.0TrpXaa: 0.0 ± 0.0
Tyr
7.738TyrAla: 7.738 ± 1.926
0.455TyrCys: 0.455 ± 0.198
1.821TyrAsp: 1.821 ± 0.652
2.731TyrGlu: 2.731 ± 0.255
0.455TyrPhe: 0.455 ± 0.198
2.731TyrGly: 2.731 ± 0.255
1.365TyrHis: 1.365 ± 0.595
2.276TyrIle: 2.276 ± 0.991
0.455TyrLys: 0.455 ± 0.198
4.552TyrLeu: 4.552 ± 1.982
0.455TyrMet: 0.455 ± 0.198
1.365TyrAsn: 1.365 ± 0.595
2.276TyrPro: 2.276 ± 0.453
0.91TyrGln: 0.91 ± 0.396
2.276TyrArg: 2.276 ± 0.991
1.821TyrSer: 1.821 ± 0.793
1.821TyrThr: 1.821 ± 0.793
0.91TyrVal: 0.91 ± 0.396
0.0TyrTrp: 0.0 ± 0.0
0.91TyrTyr: 0.91 ± 0.396
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.455XaaGln: 0.455 ± 0.198
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2198 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski