Amino acid dipepetide frequency for Sutterella wadsworthensis HGA0223

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	18.416AlaAla: 18.416 ± 0.255	1.337AlaCys: 1.337 ± 0.044	6.597AlaAsp: 6.597 ± 0.108	7.63AlaGlu: 7.63 ± 0.112	4.472AlaPhe: 4.472 ± 0.081	9.462AlaGly: 9.462 ± 0.123	2.025AlaHis: 2.025 ± 0.054	4.882AlaIle: 4.882 ± 0.085	5.298AlaLys: 5.298 ± 0.099	12.099AlaLeu: 12.099 ± 0.149	2.889AlaMet: 2.889 ± 0.059	2.882AlaAsn: 2.882 ± 0.071	4.679AlaPro: 4.679 ± 0.083	4.499AlaGln: 4.499 ± 0.085	6.215AlaArg: 6.215 ± 0.094	6.336AlaSer: 6.336 ± 0.101	4.089AlaThr: 4.089 ± 0.079	9.388AlaVal: 9.388 ± 0.121	1.458AlaTrp: 1.458 ± 0.044	2.391AlaTyr: 2.391 ± 0.054	0.0AlaXaa: 0.0 ± 0.0
Cys	1.43CysAla: 1.43 ± 0.042	0.245CysCys: 0.245 ± 0.017	0.557CysAsp: 0.557 ± 0.024	0.653CysGlu: 0.653 ± 0.03	0.457CysPhe: 0.457 ± 0.022	1.345CysGly: 1.345 ± 0.048	0.289CysHis: 0.289 ± 0.028	0.536CysIle: 0.536 ± 0.028	0.267CysLys: 0.267 ± 0.019	1.042CysLeu: 1.042 ± 0.037	0.255CysMet: 0.255 ± 0.018	0.259CysAsn: 0.259 ± 0.017	0.631CysPro: 0.631 ± 0.033	0.265CysGln: 0.265 ± 0.018	0.898CysArg: 0.898 ± 0.038	0.7CysSer: 0.7 ± 0.027	0.661CysThr: 0.661 ± 0.029	0.845CysVal: 0.845 ± 0.037	0.174CysTrp: 0.174 ± 0.015	0.261CysTyr: 0.261 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	6.114AspAla: 6.114 ± 0.092	0.613AspCys: 0.613 ± 0.032	2.788AspAsp: 2.788 ± 0.078	3.663AspGlu: 3.663 ± 0.081	2.468AspPhe: 2.468 ± 0.056	4.05AspGly: 4.05 ± 0.088	0.98AspHis: 0.98 ± 0.039	2.663AspIle: 2.663 ± 0.06	2.166AspLys: 2.166 ± 0.068	5.141AspLeu: 5.141 ± 0.091	1.269AspMet: 1.269 ± 0.043	1.374AspAsn: 1.374 ± 0.044	3.207AspPro: 3.207 ± 0.07	1.569AspGln: 1.569 ± 0.046	3.328AspArg: 3.328 ± 0.077	2.482AspSer: 2.482 ± 0.061	2.222AspThr: 2.222 ± 0.057	3.834AspVal: 3.834 ± 0.072	0.933AspTrp: 0.933 ± 0.034	1.446AspTyr: 1.446 ± 0.044	0.0AspXaa: 0.0 ± 0.0
Glu	7.716GluAla: 7.716 ± 0.148	0.555GluCys: 0.555 ± 0.027	2.913GluAsp: 2.913 ± 0.074	3.727GluGlu: 3.727 ± 0.085	1.935GluPhe: 1.935 ± 0.048	4.186GluGly: 4.186 ± 0.074	1.3GluHis: 1.3 ± 0.042	3.279GluIle: 3.279 ± 0.07	3.57GluLys: 3.57 ± 0.069	6.487GluLeu: 6.487 ± 0.103	1.578GluMet: 1.578 ± 0.043	2.097GluAsn: 2.097 ± 0.051	2.534GluPro: 2.534 ± 0.069	1.822GluGln: 1.822 ± 0.048	4.472GluArg: 4.472 ± 0.094	3.307GluSer: 3.307 ± 0.063	3.379GluThr: 3.379 ± 0.07	4.161GluVal: 4.161 ± 0.067	0.694GluTrp: 0.694 ± 0.031	1.343GluTyr: 1.343 ± 0.043	0.0GluXaa: 0.0 ± 0.0
Phe	4.572PheAla: 4.572 ± 0.075	0.555PheCys: 0.555 ± 0.03	2.483PheAsp: 2.483 ± 0.057	2.378PheGlu: 2.378 ± 0.058	1.915PhePhe: 1.915 ± 0.06	3.71PheGly: 3.71 ± 0.077	0.671PheHis: 0.671 ± 0.031	2.294PheIle: 2.294 ± 0.055	1.607PheLys: 1.607 ± 0.05	3.69PheLeu: 3.69 ± 0.074	1.003PheMet: 1.003 ± 0.036	1.422PheAsn: 1.422 ± 0.044	1.601PhePro: 1.601 ± 0.053	1.015PheGln: 1.015 ± 0.028	1.966PheArg: 1.966 ± 0.049	2.814PheSer: 2.814 ± 0.062	2.468PheThr: 2.468 ± 0.058	2.893PheVal: 2.893 ± 0.068	0.651PheTrp: 0.651 ± 0.035	1.039PheTyr: 1.039 ± 0.041	0.0PheXaa: 0.0 ± 0.0
Gly	8.116GlyAla: 8.116 ± 0.119	1.109GlyCys: 1.109 ± 0.035	3.661GlyAsp: 3.661 ± 0.081	4.44GlyGlu: 4.44 ± 0.075	3.571GlyPhe: 3.571 ± 0.067	5.889GlyGly: 5.889 ± 0.115	1.371GlyHis: 1.371 ± 0.04	5.073GlyIle: 5.073 ± 0.087	3.589GlyLys: 3.589 ± 0.071	8.154GlyLeu: 8.154 ± 0.118	2.162GlyMet: 2.162 ± 0.055	2.152GlyAsn: 2.152 ± 0.056	2.403GlyPro: 2.403 ± 0.057	2.122GlyGln: 2.122 ± 0.047	5.324GlyArg: 5.324 ± 0.095	4.799GlySer: 4.799 ± 0.106	4.573GlyThr: 4.573 ± 0.098	5.778GlyVal: 5.778 ± 0.089	1.29GlyTrp: 1.29 ± 0.039	2.128GlyTyr: 2.128 ± 0.056	0.0GlyXaa: 0.0 ± 0.0
His	1.951HisAla: 1.951 ± 0.049	0.281HisCys: 0.281 ± 0.017	0.959HisAsp: 0.959 ± 0.034	1.022HisGlu: 1.022 ± 0.035	0.886HisPhe: 0.886 ± 0.036	1.441HisGly: 1.441 ± 0.045	0.442HisHis: 0.442 ± 0.025	0.914HisIle: 0.914 ± 0.034	0.6HisLys: 0.6 ± 0.033	1.894HisLeu: 1.894 ± 0.057	0.469HisMet: 0.469 ± 0.025	0.481HisAsn: 0.481 ± 0.023	1.339HisPro: 1.339 ± 0.039	0.642HisGln: 0.642 ± 0.03	1.101HisArg: 1.101 ± 0.04	1.053HisSer: 1.053 ± 0.036	0.911HisThr: 0.911 ± 0.037	1.276HisVal: 1.276 ± 0.045	0.311HisTrp: 0.311 ± 0.021	0.549HisTyr: 0.549 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	6.343IleAla: 6.343 ± 0.096	0.749IleCys: 0.749 ± 0.031	3.436IleAsp: 3.436 ± 0.072	3.732IleGlu: 3.732 ± 0.078	2.193IlePhe: 2.193 ± 0.057	4.321IleGly: 4.321 ± 0.088	1.018IleHis: 1.018 ± 0.032	2.527IleIle: 2.527 ± 0.073	2.028IleLys: 2.028 ± 0.055	4.942IleLeu: 4.942 ± 0.086	0.976IleMet: 0.976 ± 0.037	1.77IleAsn: 1.77 ± 0.051	2.657IlePro: 2.657 ± 0.065	1.416IleGln: 1.416 ± 0.039	3.182IleArg: 3.182 ± 0.068	3.246IleSer: 3.246 ± 0.072	2.784IleThr: 2.784 ± 0.074	4.111IleVal: 4.111 ± 0.08	0.568IleTrp: 0.568 ± 0.026	1.315IleTyr: 1.315 ± 0.041	0.0IleXaa: 0.0 ± 0.0
Lys	5.151LysAla: 5.151 ± 0.082	0.414LysCys: 0.414 ± 0.025	2.446LysAsp: 2.446 ± 0.06	2.495LysGlu: 2.495 ± 0.065	1.449LysPhe: 1.449 ± 0.044	3.185LysGly: 3.185 ± 0.061	0.833LysHis: 0.833 ± 0.032	2.352LysIle: 2.352 ± 0.057	2.575LysLys: 2.575 ± 0.068	4.541LysLeu: 4.541 ± 0.073	1.226LysMet: 1.226 ± 0.037	1.924LysAsn: 1.924 ± 0.055	2.406LysPro: 2.406 ± 0.057	1.334LysGln: 1.334 ± 0.044	2.958LysArg: 2.958 ± 0.061	2.747LysSer: 2.747 ± 0.058	3.234LysThr: 3.234 ± 0.077	3.029LysVal: 3.029 ± 0.077	0.482LysTrp: 0.482 ± 0.025	1.025LysTyr: 1.025 ± 0.037	0.0LysXaa: 0.0 ± 0.0
Leu	11.402LeuAla: 11.402 ± 0.141	1.25LeuCys: 1.25 ± 0.039	5.042LeuAsp: 5.042 ± 0.08	6.139LeuGlu: 6.139 ± 0.116	4.034LeuPhe: 4.034 ± 0.088	7.503LeuGly: 7.503 ± 0.125	1.666LeuHis: 1.666 ± 0.043	5.179LeuIle: 5.179 ± 0.089	5.134LeuLys: 5.134 ± 0.078	9.729LeuLeu: 9.729 ± 0.167	2.614LeuMet: 2.614 ± 0.068	3.151LeuAsn: 3.151 ± 0.061	5.392LeuPro: 5.392 ± 0.088	2.869LeuGln: 2.869 ± 0.06	5.924LeuArg: 5.924 ± 0.103	7.247LeuSer: 7.247 ± 0.098	6.385LeuThr: 6.385 ± 0.109	6.355LeuVal: 6.355 ± 0.106	1.196LeuTrp: 1.196 ± 0.046	2.302LeuTyr: 2.302 ± 0.051	0.0LeuXaa: 0.0 ± 0.0
Met	2.508MetAla: 2.508 ± 0.054	0.206MetCys: 0.206 ± 0.016	1.127MetAsp: 1.127 ± 0.031	1.244MetGlu: 1.244 ± 0.04	0.671MetPhe: 0.671 ± 0.029	1.96MetGly: 1.96 ± 0.05	0.554MetHis: 0.554 ± 0.027	1.283MetIle: 1.283 ± 0.045	1.503MetLys: 1.503 ± 0.039	2.701MetLeu: 2.701 ± 0.056	0.802MetMet: 0.802 ± 0.033	0.98MetAsn: 0.98 ± 0.034	1.531MetPro: 1.531 ± 0.049	0.968MetGln: 0.968 ± 0.036	1.705MetArg: 1.705 ± 0.046	1.587MetSer: 1.587 ± 0.046	2.025MetThr: 2.025 ± 0.049	1.525MetVal: 1.525 ± 0.044	0.148MetTrp: 0.148 ± 0.013	0.359MetTyr: 0.359 ± 0.022	0.0MetXaa: 0.0 ± 0.0
Asn	3.773AsnAla: 3.773 ± 0.079	0.331AsnCys: 0.331 ± 0.022	1.546AsnAsp: 1.546 ± 0.044	1.703AsnGlu: 1.703 ± 0.041	1.3AsnPhe: 1.3 ± 0.038	2.601AsnGly: 2.601 ± 0.06	0.57AsnHis: 0.57 ± 0.027	1.601AsnIle: 1.601 ± 0.046	1.109AsnLys: 1.109 ± 0.044	3.0AsnLeu: 3.0 ± 0.056	0.634AsnMet: 0.634 ± 0.03	0.973AsnAsn: 0.973 ± 0.035	2.138AsnPro: 2.138 ± 0.059	0.926AsnGln: 0.926 ± 0.034	1.835AsnArg: 1.835 ± 0.039	1.57AsnSer: 1.57 ± 0.045	1.639AsnThr: 1.639 ± 0.053	2.269AsnVal: 2.269 ± 0.06	0.454AsnTrp: 0.454 ± 0.024	0.863AsnTyr: 0.863 ± 0.037	0.0AsnXaa: 0.0 ± 0.0
Pro	5.487ProAla: 5.487 ± 0.097	0.492ProCys: 0.492 ± 0.023	2.758ProAsp: 2.758 ± 0.068	3.96ProGlu: 3.96 ± 0.085	1.92ProPhe: 1.92 ± 0.05	3.429ProGly: 3.429 ± 0.071	0.948ProHis: 0.948 ± 0.037	2.438ProIle: 2.438 ± 0.056	2.565ProLys: 2.565 ± 0.058	4.295ProLeu: 4.295 ± 0.078	1.176ProMet: 1.176 ± 0.037	1.584ProAsn: 1.584 ± 0.045	1.589ProPro: 1.589 ± 0.049	1.914ProGln: 1.914 ± 0.056	2.14ProArg: 2.14 ± 0.061	2.698ProSer: 2.698 ± 0.053	2.418ProThr: 2.418 ± 0.056	3.716ProVal: 3.716 ± 0.07	0.695ProTrp: 0.695 ± 0.032	1.327ProTyr: 1.327 ± 0.041	0.0ProXaa: 0.0 ± 0.0
Gln	3.623GlnAla: 3.623 ± 0.071	0.334GlnCys: 0.334 ± 0.021	1.232GlnAsp: 1.232 ± 0.043	1.671GlnGlu: 1.671 ± 0.049	1.165GlnPhe: 1.165 ± 0.031	2.229GlnGly: 2.229 ± 0.049	0.639GlnHis: 0.639 ± 0.025	1.864GlnIle: 1.864 ± 0.049	1.938GlnLys: 1.938 ± 0.052	2.856GlnLeu: 2.856 ± 0.065	0.877GlnMet: 0.877 ± 0.033	1.096GlnAsn: 1.096 ± 0.035	1.507GlnPro: 1.507 ± 0.043	1.127GlnGln: 1.127 ± 0.04	1.963GlnArg: 1.963 ± 0.053	1.945GlnSer: 1.945 ± 0.051	2.169GlnThr: 2.169 ± 0.047	2.053GlnVal: 2.053 ± 0.048	0.432GlnTrp: 0.432 ± 0.022	0.83GlnTyr: 0.83 ± 0.031	0.0GlnXaa: 0.0 ± 0.0
Arg	6.21ArgAla: 6.21 ± 0.108	0.661ArgCys: 0.661 ± 0.03	2.808ArgAsp: 2.808 ± 0.064	4.135ArgGlu: 4.135 ± 0.083	2.7ArgPhe: 2.7 ± 0.064	3.819ArgGly: 3.819 ± 0.072	1.199ArgHis: 1.199 ± 0.037	3.894ArgIle: 3.894 ± 0.066	2.197ArgLys: 2.197 ± 0.051	6.427ArgLeu: 6.427 ± 0.103	1.845ArgMet: 1.845 ± 0.048	1.646ArgAsn: 1.646 ± 0.046	2.72ArgPro: 2.72 ± 0.064	2.109ArgGln: 2.109 ± 0.058	5.046ArgArg: 5.046 ± 0.107	3.675ArgSer: 3.675 ± 0.066	3.563ArgThr: 3.563 ± 0.069	3.971ArgVal: 3.971 ± 0.077	0.94ArgTrp: 0.94 ± 0.038	1.607ArgTyr: 1.607 ± 0.038	0.0ArgXaa: 0.0 ± 0.0
Ser	7.235SerAla: 7.235 ± 0.116	0.603SerCys: 0.603 ± 0.025	3.009SerAsp: 3.009 ± 0.062	3.177SerGlu: 3.177 ± 0.067	2.495SerPhe: 2.495 ± 0.055	5.496SerGly: 5.496 ± 0.085	0.992SerHis: 0.992 ± 0.038	3.442SerIle: 3.442 ± 0.067	2.264SerLys: 2.264 ± 0.058	5.962SerLeu: 5.962 ± 0.1	1.5SerMet: 1.5 ± 0.042	1.653SerAsn: 1.653 ± 0.042	2.958SerPro: 2.958 ± 0.064	1.716SerGln: 1.716 ± 0.049	3.453SerArg: 3.453 ± 0.071	4.004SerSer: 4.004 ± 0.083	3.294SerThr: 3.294 ± 0.068	4.374SerVal: 4.374 ± 0.08	0.85SerTrp: 0.85 ± 0.031	1.359SerTyr: 1.359 ± 0.045	0.0SerXaa: 0.0 ± 0.0
Thr	6.671ThrAla: 6.671 ± 0.099	0.533ThrCys: 0.533 ± 0.027	2.883ThrAsp: 2.883 ± 0.065	2.783ThrGlu: 2.783 ± 0.064	2.306ThrPhe: 2.306 ± 0.057	4.774ThrGly: 4.774 ± 0.092	1.117ThrHis: 1.117 ± 0.035	3.091ThrIle: 3.091 ± 0.074	2.115ThrLys: 2.115 ± 0.06	5.818ThrLeu: 5.818 ± 0.09	1.267ThrMet: 1.267 ± 0.041	1.709ThrAsn: 1.709 ± 0.06	3.259ThrPro: 3.259 ± 0.066	1.644ThrGln: 1.644 ± 0.047	2.538ThrArg: 2.538 ± 0.057	2.981ThrSer: 2.981 ± 0.068	3.095ThrThr: 3.095 ± 0.082	4.433ThrVal: 4.433 ± 0.085	0.628ThrTrp: 0.628 ± 0.027	1.318ThrTyr: 1.318 ± 0.044	0.0ThrXaa: 0.0 ± 0.0
Val	6.341ValAla: 6.341 ± 0.092	0.989ValCys: 0.989 ± 0.04	4.0ValAsp: 4.0 ± 0.075	4.398ValGlu: 4.398 ± 0.083	3.153ValPhe: 3.153 ± 0.067	5.157ValGly: 5.157 ± 0.099	1.246ValHis: 1.246 ± 0.04	4.232ValIle: 4.232 ± 0.08	3.855ValLys: 3.855 ± 0.075	7.848ValLeu: 7.848 ± 0.098	1.938ValMet: 1.938 ± 0.06	2.465ValAsn: 2.465 ± 0.064	3.381ValPro: 3.381 ± 0.063	2.168ValGln: 2.168 ± 0.057	4.546ValArg: 4.546 ± 0.078	4.455ValSer: 4.455 ± 0.09	3.945ValThr: 3.945 ± 0.086	5.798ValVal: 5.798 ± 0.105	0.938ValTrp: 0.938 ± 0.045	1.647ValTyr: 1.647 ± 0.044	0.0ValXaa: 0.0 ± 0.0
Trp	1.232TrpAla: 1.232 ± 0.038	0.19TrpCys: 0.19 ± 0.016	0.595TrpAsp: 0.595 ± 0.028	0.667TrpGlu: 0.667 ± 0.027	0.544TrpPhe: 0.544 ± 0.026	0.989TrpGly: 0.989 ± 0.039	0.304TrpHis: 0.304 ± 0.018	0.732TrpIle: 0.732 ± 0.032	0.599TrpLys: 0.599 ± 0.029	1.614TrpLeu: 1.614 ± 0.049	0.412TrpMet: 0.412 ± 0.022	0.499TrpAsn: 0.499 ± 0.025	0.481TrpPro: 0.481 ± 0.024	0.55TrpGln: 0.55 ± 0.027	1.039TrpArg: 1.039 ± 0.036	0.756TrpSer: 0.756 ± 0.03	0.826TrpThr: 0.826 ± 0.036	0.886TrpVal: 0.886 ± 0.035	0.183TrpTrp: 0.183 ± 0.015	0.313TrpTyr: 0.313 ± 0.022	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.753TyrAla: 2.753 ± 0.054	0.321TyrCys: 0.321 ± 0.018	1.466TyrAsp: 1.466 ± 0.048	1.439TyrGlu: 1.439 ± 0.039	1.115TyrPhe: 1.115 ± 0.038	2.159TyrGly: 2.159 ± 0.057	0.359TyrHis: 0.359 ± 0.02	1.039TyrIle: 1.039 ± 0.044	0.826TyrLys: 0.826 ± 0.033	2.275TyrLeu: 2.275 ± 0.061	0.493TyrMet: 0.493 ± 0.021	0.719TyrAsn: 0.719 ± 0.03	1.138TyrPro: 1.138 ± 0.037	0.875TyrGln: 0.875 ± 0.036	1.537TyrArg: 1.537 ± 0.047	1.436TyrSer: 1.436 ± 0.044	1.284TyrThr: 1.284 ± 0.042	1.803TyrVal: 1.803 ± 0.045	0.384TyrTrp: 0.384 ± 0.024	0.584TyrTyr: 0.584 ± 0.026	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2393 proteins (840102 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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