Amino acid dipepetide frequency for Nannocystis exedens

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	21.531AlaAla: 21.531 ± 0.142	2.302AlaCys: 2.302 ± 0.043	7.51AlaAsp: 7.51 ± 0.053	8.508AlaGlu: 8.508 ± 0.071	3.675AlaPhe: 3.675 ± 0.041	12.326AlaGly: 12.326 ± 0.072	2.58AlaHis: 2.58 ± 0.035	4.7AlaIle: 4.7 ± 0.041	2.739AlaLys: 2.739 ± 0.048	15.546AlaLeu: 15.546 ± 0.11	2.406AlaMet: 2.406 ± 0.03	1.978AlaAsn: 1.978 ± 0.026	8.639AlaPro: 8.639 ± 0.079	3.679AlaGln: 3.679 ± 0.036	11.749AlaArg: 11.749 ± 0.096	6.407AlaSer: 6.407 ± 0.046	6.578AlaThr: 6.578 ± 0.046	9.577AlaVal: 9.577 ± 0.057	2.047AlaTrp: 2.047 ± 0.029	2.288AlaTyr: 2.288 ± 0.03	0.001AlaXaa: 0.001 ± 0.0
Cys	1.593CysAla: 1.593 ± 0.027	0.194CysCys: 0.194 ± 0.009	1.275CysAsp: 1.275 ± 0.038	0.924CysGlu: 0.924 ± 0.022	0.388CysPhe: 0.388 ± 0.013	1.61CysGly: 1.61 ± 0.042	0.298CysHis: 0.298 ± 0.012	0.354CysIle: 0.354 ± 0.013	0.363CysLys: 0.363 ± 0.015	1.106CysLeu: 1.106 ± 0.022	0.229CysMet: 0.229 ± 0.01	0.349CysAsn: 0.349 ± 0.013	0.891CysPro: 0.891 ± 0.024	0.415CysGln: 0.415 ± 0.014	0.793CysArg: 0.793 ± 0.017	0.763CysSer: 0.763 ± 0.017	0.834CysThr: 0.834 ± 0.025	1.033CysVal: 1.033 ± 0.021	0.17CysTrp: 0.17 ± 0.011	0.245CysTyr: 0.245 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	7.964AspAla: 7.964 ± 0.052	0.886AspCys: 0.886 ± 0.028	4.652AspAsp: 4.652 ± 0.053	3.992AspGlu: 3.992 ± 0.041	1.888AspPhe: 1.888 ± 0.026	6.747AspGly: 6.747 ± 0.084	1.246AspHis: 1.246 ± 0.019	1.951AspIle: 1.951 ± 0.022	1.303AspLys: 1.303 ± 0.027	6.649AspLeu: 6.649 ± 0.052	0.995AspMet: 0.995 ± 0.017	1.211AspAsn: 1.211 ± 0.024	5.35AspPro: 5.35 ± 0.049	1.467AspGln: 1.467 ± 0.022	4.391AspArg: 4.391 ± 0.036	2.495AspSer: 2.495 ± 0.031	2.719AspThr: 2.719 ± 0.041	4.463AspVal: 4.463 ± 0.04	0.72AspTrp: 0.72 ± 0.017	1.165AspTyr: 1.165 ± 0.02	0.0AspXaa: 0.0 ± 0.0
Glu	8.319GluAla: 8.319 ± 0.066	0.739GluCys: 0.739 ± 0.02	2.912GluAsp: 2.912 ± 0.036	2.971GluGlu: 2.971 ± 0.038	1.884GluPhe: 1.884 ± 0.027	4.488GluGly: 4.488 ± 0.04	1.57GluHis: 1.57 ± 0.023	2.308GluIle: 2.308 ± 0.029	1.283GluLys: 1.283 ± 0.032	7.708GluLeu: 7.708 ± 0.065	0.895GluMet: 0.895 ± 0.017	0.928GluAsn: 0.928 ± 0.018	4.191GluPro: 4.191 ± 0.05	2.415GluGln: 2.415 ± 0.029	5.764GluArg: 5.764 ± 0.056	2.438GluSer: 2.438 ± 0.026	2.763GluThr: 2.763 ± 0.03	4.852GluVal: 4.852 ± 0.046	0.756GluTrp: 0.756 ± 0.017	1.033GluTyr: 1.033 ± 0.018	0.0GluXaa: 0.0 ± 0.0
Phe	4.42PheAla: 4.42 ± 0.037	0.426PheCys: 0.426 ± 0.012	2.261PheAsp: 2.261 ± 0.028	1.945PheGlu: 1.945 ± 0.025	1.098PhePhe: 1.098 ± 0.021	3.053PheGly: 3.053 ± 0.033	0.693PheHis: 0.693 ± 0.016	0.998PheIle: 0.998 ± 0.019	0.723PheLys: 0.723 ± 0.016	2.549PheLeu: 2.549 ± 0.036	0.524PheMet: 0.524 ± 0.013	0.714PheAsn: 0.714 ± 0.017	1.437PhePro: 1.437 ± 0.021	0.732PheGln: 0.732 ± 0.014	1.915PheArg: 1.915 ± 0.028	1.657PheSer: 1.657 ± 0.022	1.889PheThr: 1.889 ± 0.026	2.793PheVal: 2.793 ± 0.029	0.4PheTrp: 0.4 ± 0.011	0.759PheTyr: 0.759 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	10.71GlyAla: 10.71 ± 0.074	1.455GlyCys: 1.455 ± 0.033	6.415GlyAsp: 6.415 ± 0.067	6.178GlyGlu: 6.178 ± 0.053	2.898GlyPhe: 2.898 ± 0.036	8.365GlyGly: 8.365 ± 0.079	1.94GlyHis: 1.94 ± 0.027	2.723GlyIle: 2.723 ± 0.032	2.454GlyLys: 2.454 ± 0.04	9.036GlyLeu: 9.036 ± 0.06	1.706GlyMet: 1.706 ± 0.023	1.864GlyAsn: 1.864 ± 0.033	5.558GlyPro: 5.558 ± 0.058	2.824GlyGln: 2.824 ± 0.036	6.609GlyArg: 6.609 ± 0.056	4.704GlySer: 4.704 ± 0.039	5.02GlyThr: 5.02 ± 0.049	6.597GlyVal: 6.597 ± 0.055	1.356GlyTrp: 1.356 ± 0.025	1.874GlyTyr: 1.874 ± 0.028	0.001GlyXaa: 0.001 ± 0.0
His	2.861HisAla: 2.861 ± 0.033	0.288HisCys: 0.288 ± 0.01	1.374HisAsp: 1.374 ± 0.023	1.422HisGlu: 1.422 ± 0.021	0.725HisPhe: 0.725 ± 0.015	2.11HisGly: 2.11 ± 0.029	0.629HisHis: 0.629 ± 0.016	0.583HisIle: 0.583 ± 0.014	0.42HisLys: 0.42 ± 0.011	2.206HisLeu: 2.206 ± 0.028	0.341HisMet: 0.341 ± 0.01	0.419HisAsn: 0.419 ± 0.011	1.519HisPro: 1.519 ± 0.021	0.52HisGln: 0.52 ± 0.012	1.829HisArg: 1.829 ± 0.024	0.834HisSer: 0.834 ± 0.019	0.927HisThr: 0.927 ± 0.021	1.898HisVal: 1.898 ± 0.025	0.286HisTrp: 0.286 ± 0.01	0.509HisTyr: 0.509 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	4.956IleAla: 4.956 ± 0.045	0.375IleCys: 0.375 ± 0.012	2.897IleAsp: 2.897 ± 0.03	2.533IleGlu: 2.533 ± 0.03	0.959IlePhe: 0.959 ± 0.019	3.184IleGly: 3.184 ± 0.03	0.839IleHis: 0.839 ± 0.016	0.888IleIle: 0.888 ± 0.021	0.808IleLys: 0.808 ± 0.018	2.735IleLeu: 2.735 ± 0.031	0.367IleMet: 0.367 ± 0.01	0.673IleAsn: 0.673 ± 0.016	1.747IlePro: 1.747 ± 0.023	0.869IleGln: 0.869 ± 0.017	2.312IleArg: 2.312 ± 0.03	1.511IleSer: 1.511 ± 0.024	1.781IleThr: 1.781 ± 0.027	3.0IleVal: 3.0 ± 0.029	0.338IleTrp: 0.338 ± 0.011	0.737IleTyr: 0.737 ± 0.016	0.0IleXaa: 0.0 ± 0.0
Lys	2.606LysAla: 2.606 ± 0.048	0.242LysCys: 0.242 ± 0.009	1.205LysAsp: 1.205 ± 0.027	0.994LysGlu: 0.994 ± 0.023	0.716LysPhe: 0.716 ± 0.018	1.606LysGly: 1.606 ± 0.031	0.482LysHis: 0.482 ± 0.012	1.16LysIle: 1.16 ± 0.025	0.958LysLys: 0.958 ± 0.032	2.499LysLeu: 2.499 ± 0.035	0.415LysMet: 0.415 ± 0.011	0.554LysAsn: 0.554 ± 0.016	1.594LysPro: 1.594 ± 0.028	0.843LysGln: 0.843 ± 0.015	1.557LysArg: 1.557 ± 0.024	1.125LysSer: 1.125 ± 0.021	1.267LysThr: 1.267 ± 0.025	1.741LysVal: 1.741 ± 0.027	0.267LysTrp: 0.267 ± 0.009	0.457LysTyr: 0.457 ± 0.013	0.0LysXaa: 0.0 ± 0.0
Leu	16.729LeuAla: 16.729 ± 0.113	1.219LeuCys: 1.219 ± 0.021	6.474LeuAsp: 6.474 ± 0.047	5.851LeuGlu: 5.851 ± 0.051	2.911LeuPhe: 2.911 ± 0.03	9.471LeuGly: 9.471 ± 0.065	2.319LeuHis: 2.319 ± 0.027	2.728LeuIle: 2.728 ± 0.031	2.118LeuLys: 2.118 ± 0.032	10.597LeuLeu: 10.597 ± 0.082	1.451LeuMet: 1.451 ± 0.022	1.517LeuAsn: 1.517 ± 0.023	6.085LeuPro: 6.085 ± 0.052	3.211LeuGln: 3.211 ± 0.031	9.378LeuArg: 9.378 ± 0.067	5.049LeuSer: 5.049 ± 0.047	4.975LeuThr: 4.975 ± 0.039	8.614LeuVal: 8.614 ± 0.064	1.42LeuTrp: 1.42 ± 0.028	1.94LeuTyr: 1.94 ± 0.028	0.0LeuXaa: 0.0 ± 0.0
Met	1.926MetAla: 1.926 ± 0.026	0.201MetCys: 0.201 ± 0.008	0.675MetAsp: 0.675 ± 0.016	0.663MetGlu: 0.663 ± 0.014	0.586MetPhe: 0.586 ± 0.014	1.129MetGly: 1.129 ± 0.02	0.423MetHis: 0.423 ± 0.011	0.682MetIle: 0.682 ± 0.014	0.478MetLys: 0.478 ± 0.011	1.791MetLeu: 1.791 ± 0.025	0.349MetMet: 0.349 ± 0.011	0.453MetAsn: 0.453 ± 0.012	1.141MetPro: 1.141 ± 0.02	0.595MetGln: 0.595 ± 0.015	1.466MetArg: 1.466 ± 0.021	1.398MetSer: 1.398 ± 0.022	1.237MetThr: 1.237 ± 0.019	1.122MetVal: 1.122 ± 0.019	0.201MetTrp: 0.201 ± 0.008	0.284MetTyr: 0.284 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	2.029AsnAla: 2.029 ± 0.029	0.28AsnCys: 0.28 ± 0.011	1.078AsnAsp: 1.078 ± 0.024	0.88AsnGlu: 0.88 ± 0.016	0.701AsnPhe: 0.701 ± 0.015	1.64AsnGly: 1.64 ± 0.033	0.417AsnHis: 0.417 ± 0.012	0.744AsnIle: 0.744 ± 0.018	0.47AsnLys: 0.47 ± 0.012	2.0AsnLeu: 2.0 ± 0.028	0.319AsnMet: 0.319 ± 0.011	0.629AsnAsn: 0.629 ± 0.02	1.394AsnPro: 1.394 ± 0.025	0.572AsnGln: 0.572 ± 0.016	1.146AsnArg: 1.146 ± 0.02	0.857AsnSer: 0.857 ± 0.022	1.03AsnThr: 1.03 ± 0.02	1.342AsnVal: 1.342 ± 0.024	0.238AsnTrp: 0.238 ± 0.008	0.48AsnTyr: 0.48 ± 0.014	0.0AsnXaa: 0.0 ± 0.0
Pro	9.573ProAla: 9.573 ± 0.075	0.645ProCys: 0.645 ± 0.017	4.314ProAsp: 4.314 ± 0.041	4.775ProGlu: 4.775 ± 0.043	1.717ProPhe: 1.717 ± 0.023	6.508ProGly: 6.508 ± 0.056	1.152ProHis: 1.152 ± 0.021	2.018ProIle: 2.018 ± 0.025	1.391ProLys: 1.391 ± 0.028	5.68ProLeu: 5.68 ± 0.044	1.143ProMet: 1.143 ± 0.021	1.211ProAsn: 1.211 ± 0.024	5.452ProPro: 5.452 ± 0.072	1.816ProGln: 1.816 ± 0.027	4.674ProArg: 4.674 ± 0.045	3.331ProSer: 3.331 ± 0.037	3.7ProThr: 3.7 ± 0.04	4.429ProVal: 4.429 ± 0.04	0.962ProTrp: 0.962 ± 0.016	1.071ProTyr: 1.071 ± 0.019	0.001ProXaa: 0.001 ± 0.0
Gln	4.073GlnAla: 4.073 ± 0.043	0.421GlnCys: 0.421 ± 0.017	1.329GlnAsp: 1.329 ± 0.018	1.369GlnGlu: 1.369 ± 0.024	0.93GlnPhe: 0.93 ± 0.017	2.212GlnGly: 2.212 ± 0.034	0.668GlnHis: 0.668 ± 0.014	1.394GlnIle: 1.394 ± 0.022	0.694GlnLys: 0.694 ± 0.017	3.136GlnLeu: 3.136 ± 0.039	0.495GlnMet: 0.495 ± 0.013	0.571GlnAsn: 0.571 ± 0.013	1.984GlnPro: 1.984 ± 0.026	1.165GlnGln: 1.165 ± 0.023	2.704GlnArg: 2.704 ± 0.033	1.253GlnSer: 1.253 ± 0.021	1.383GlnThr: 1.383 ± 0.021	2.534GlnVal: 2.534 ± 0.027	0.47GlnTrp: 0.47 ± 0.014	0.555GlnTyr: 0.555 ± 0.014	0.0GlnXaa: 0.0 ± 0.0
Arg	10.93ArgAla: 10.93 ± 0.085	0.945ArgCys: 0.945 ± 0.02	4.507ArgAsp: 4.507 ± 0.042	5.073ArgGlu: 5.073 ± 0.052	2.836ArgPhe: 2.836 ± 0.032	6.467ArgGly: 6.467 ± 0.056	1.83ArgHis: 1.83 ± 0.023	2.831ArgIle: 2.831 ± 0.029	1.757ArgLys: 1.757 ± 0.024	8.83ArgLeu: 8.83 ± 0.075	1.49ArgMet: 1.49 ± 0.019	1.178ArgAsn: 1.178 ± 0.02	4.967ArgPro: 4.967 ± 0.054	2.162ArgGln: 2.162 ± 0.026	7.904ArgArg: 7.904 ± 0.079	3.909ArgSer: 3.909 ± 0.04	3.615ArgThr: 3.615 ± 0.042	6.079ArgVal: 6.079 ± 0.049	1.463ArgTrp: 1.463 ± 0.022	1.678ArgTyr: 1.678 ± 0.023	0.0ArgXaa: 0.0 ± 0.0
Ser	5.983SerAla: 5.983 ± 0.042	0.721SerCys: 0.721 ± 0.019	2.875SerAsp: 2.875 ± 0.029	2.849SerGlu: 2.849 ± 0.03	1.678SerPhe: 1.678 ± 0.023	4.981SerGly: 4.981 ± 0.051	0.994SerHis: 0.994 ± 0.019	1.602SerIle: 1.602 ± 0.023	1.058SerLys: 1.058 ± 0.021	5.073SerLeu: 5.073 ± 0.044	0.943SerMet: 0.943 ± 0.014	0.99SerAsn: 0.99 ± 0.023	3.617SerPro: 3.617 ± 0.038	1.405SerGln: 1.405 ± 0.02	3.507SerArg: 3.507 ± 0.038	3.059SerSer: 3.059 ± 0.043	3.273SerThr: 3.273 ± 0.049	3.254SerVal: 3.254 ± 0.032	0.694SerTrp: 0.694 ± 0.014	0.982SerTyr: 0.982 ± 0.017	0.001SerXaa: 0.001 ± 0.001
Thr	6.484ThrAla: 6.484 ± 0.043	0.945ThrCys: 0.945 ± 0.024	3.169ThrAsp: 3.169 ± 0.045	2.49ThrGlu: 2.49 ± 0.031	1.606ThrPhe: 1.606 ± 0.021	5.63ThrGly: 5.63 ± 0.052	0.978ThrHis: 0.978 ± 0.017	2.124ThrIle: 2.124 ± 0.028	0.923ThrLys: 0.923 ± 0.02	5.127ThrLeu: 5.127 ± 0.044	0.924ThrMet: 0.924 ± 0.018	0.956ThrAsn: 0.956 ± 0.02	3.665ThrPro: 3.665 ± 0.033	1.253ThrGln: 1.253 ± 0.02	3.596ThrArg: 3.596 ± 0.035	3.398ThrSer: 3.398 ± 0.046	5.0ThrThr: 5.0 ± 0.11	3.753ThrVal: 3.753 ± 0.035	0.861ThrTrp: 0.861 ± 0.015	1.113ThrTyr: 1.113 ± 0.02	0.0ThrXaa: 0.0 ± 0.0
Val	10.311ValAla: 10.311 ± 0.065	1.062ValCys: 1.062 ± 0.025	5.188ValAsp: 5.188 ± 0.041	4.955ValGlu: 4.955 ± 0.044	2.516ValPhe: 2.516 ± 0.031	6.096ValGly: 6.096 ± 0.048	1.834ValHis: 1.834 ± 0.024	2.539ValIle: 2.539 ± 0.028	1.585ValLys: 1.585 ± 0.03	8.028ValLeu: 8.028 ± 0.06	1.185ValMet: 1.185 ± 0.023	1.231ValAsn: 1.231 ± 0.022	4.509ValPro: 4.509 ± 0.039	2.213ValGln: 2.213 ± 0.03	6.197ValArg: 6.197 ± 0.049	3.445ValSer: 3.445 ± 0.037	4.046ValThr: 4.046 ± 0.039	6.782ValVal: 6.782 ± 0.058	1.01ValTrp: 1.01 ± 0.019	1.591ValTyr: 1.591 ± 0.023	0.0ValXaa: 0.0 ± 0.0
Trp	1.439TrpAla: 1.439 ± 0.024	0.179TrpCys: 0.179 ± 0.008	0.796TrpAsp: 0.796 ± 0.019	0.658TrpGlu: 0.658 ± 0.014	0.486TrpPhe: 0.486 ± 0.012	0.991TrpGly: 0.991 ± 0.02	0.326TrpHis: 0.326 ± 0.009	0.601TrpIle: 0.601 ± 0.015	0.303TrpLys: 0.303 ± 0.01	1.815TrpLeu: 1.815 ± 0.029	0.274TrpMet: 0.274 ± 0.009	0.345TrpAsn: 0.345 ± 0.01	0.815TrpPro: 0.815 ± 0.015	0.576TrpGln: 0.576 ± 0.013	1.265TrpArg: 1.265 ± 0.022	0.971TrpSer: 0.971 ± 0.019	0.927TrpThr: 0.927 ± 0.018	0.882TrpVal: 0.882 ± 0.017	0.279TrpTrp: 0.279 ± 0.011	0.301TrpTyr: 0.301 ± 0.012	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.331TyrAla: 2.331 ± 0.028	0.303TyrCys: 0.303 ± 0.011	1.348TyrAsp: 1.348 ± 0.023	1.187TyrGlu: 1.187 ± 0.021	0.788TyrPhe: 0.788 ± 0.017	1.671TyrGly: 1.671 ± 0.025	0.484TyrHis: 0.484 ± 0.012	0.578TyrIle: 0.578 ± 0.013	0.462TyrLys: 0.462 ± 0.013	1.946TyrLeu: 1.946 ± 0.026	0.349TyrMet: 0.349 ± 0.01	0.471TyrAsn: 0.471 ± 0.014	1.005TyrPro: 1.005 ± 0.018	0.607TyrGln: 0.607 ± 0.015	1.695TyrArg: 1.695 ± 0.024	0.936TyrSer: 0.936 ± 0.018	1.03TyrThr: 1.03 ± 0.022	1.577TyrVal: 1.577 ± 0.022	0.295TyrTrp: 0.295 ± 0.01	0.543TyrTyr: 0.543 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.001	0.0XaaGln: 0.0 ± 0.0	0.001XaaArg: 0.001 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.01XaaXaa: 0.01 ± 0.003

Statistics based on 9143 proteins (3282201 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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