Amino acid dipepetide frequency for Saccharicrinis fermentans DSM 9555 = JCM 21142

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.174AlaAla: 4.174 ± 0.064
0.691AlaCys: 0.691 ± 0.023
3.532AlaAsp: 3.532 ± 0.05
3.757AlaGlu: 3.757 ± 0.05
3.135AlaPhe: 3.135 ± 0.049
4.332AlaGly: 4.332 ± 0.07
1.307AlaHis: 1.307 ± 0.03
5.012AlaIle: 5.012 ± 0.061
4.194AlaLys: 4.194 ± 0.06
5.886AlaLeu: 5.886 ± 0.071
1.586AlaMet: 1.586 ± 0.034
3.182AlaAsn: 3.182 ± 0.046
1.887AlaPro: 1.887 ± 0.032
2.575AlaGln: 2.575 ± 0.044
2.203AlaArg: 2.203 ± 0.042
4.319AlaSer: 4.319 ± 0.069
3.184AlaThr: 3.184 ± 0.052
3.834AlaVal: 3.834 ± 0.052
0.744AlaTrp: 0.744 ± 0.022
2.871AlaTyr: 2.871 ± 0.046
0.0AlaXaa: 0.0 ± 0.0
Cys
0.56CysAla: 0.56 ± 0.019
0.122CysCys: 0.122 ± 0.009
0.545CysAsp: 0.545 ± 0.02
0.549CysGlu: 0.549 ± 0.023
0.487CysPhe: 0.487 ± 0.018
0.692CysGly: 0.692 ± 0.021
0.245CysHis: 0.245 ± 0.014
0.713CysIle: 0.713 ± 0.019
0.617CysLys: 0.617 ± 0.022
0.806CysLeu: 0.806 ± 0.021
0.226CysMet: 0.226 ± 0.013
0.51CysAsn: 0.51 ± 0.019
0.368CysPro: 0.368 ± 0.017
0.293CysGln: 0.293 ± 0.014
0.323CysArg: 0.323 ± 0.015
0.665CysSer: 0.665 ± 0.024
0.505CysThr: 0.505 ± 0.02
0.621CysVal: 0.621 ± 0.023
0.124CysTrp: 0.124 ± 0.008
0.381CysTyr: 0.381 ± 0.02
0.0CysXaa: 0.0 ± 0.0
Asp
3.595AspAla: 3.595 ± 0.056
0.511AspCys: 0.511 ± 0.017
3.227AspAsp: 3.227 ± 0.055
3.86AspGlu: 3.86 ± 0.056
3.32AspPhe: 3.32 ± 0.046
4.07AspGly: 4.07 ± 0.068
1.138AspHis: 1.138 ± 0.03
4.617AspIle: 4.617 ± 0.057
4.21AspLys: 4.21 ± 0.054
4.986AspLeu: 4.986 ± 0.058
1.447AspMet: 1.447 ± 0.033
2.991AspAsn: 2.991 ± 0.047
1.944AspPro: 1.944 ± 0.04
1.824AspGln: 1.824 ± 0.031
2.065AspArg: 2.065 ± 0.03
3.247AspSer: 3.247 ± 0.047
2.527AspThr: 2.527 ± 0.045
3.824AspVal: 3.824 ± 0.05
0.849AspTrp: 0.849 ± 0.025
2.971AspTyr: 2.971 ± 0.05
0.0AspXaa: 0.0 ± 0.0
Glu
4.174GluAla: 4.174 ± 0.065
0.493GluCys: 0.493 ± 0.018
3.598GluAsp: 3.598 ± 0.045
4.734GluGlu: 4.734 ± 0.064
2.655GluPhe: 2.655 ± 0.041
4.082GluGly: 4.082 ± 0.05
1.133GluHis: 1.133 ± 0.029
4.942GluIle: 4.942 ± 0.06
5.462GluLys: 5.462 ± 0.065
6.307GluLeu: 6.307 ± 0.071
1.901GluMet: 1.901 ± 0.036
3.935GluAsn: 3.935 ± 0.051
1.649GluPro: 1.649 ± 0.031
2.305GluGln: 2.305 ± 0.044
2.614GluArg: 2.614 ± 0.049
3.49GluSer: 3.49 ± 0.047
3.007GluThr: 3.007 ± 0.046
4.46GluVal: 4.46 ± 0.055
0.795GluTrp: 0.795 ± 0.021
2.59GluTyr: 2.59 ± 0.041
0.0GluXaa: 0.0 ± 0.0
Phe
2.736PheAla: 2.736 ± 0.047
0.513PheCys: 0.513 ± 0.017
3.063PheAsp: 3.063 ± 0.043
3.072PheGlu: 3.072 ± 0.05
2.533PhePhe: 2.533 ± 0.043
3.142PheGly: 3.142 ± 0.049
0.908PheHis: 0.908 ± 0.023
3.642PheIle: 3.642 ± 0.055
3.421PheLys: 3.421 ± 0.053
4.131PheLeu: 4.131 ± 0.057
1.238PheMet: 1.238 ± 0.031
2.954PheAsn: 2.954 ± 0.048
1.552PhePro: 1.552 ± 0.036
1.389PheGln: 1.389 ± 0.03
1.666PheArg: 1.666 ± 0.034
3.945PheSer: 3.945 ± 0.049
2.696PheThr: 2.696 ± 0.046
3.284PheVal: 3.284 ± 0.049
0.601PheTrp: 0.601 ± 0.023
2.179PheTyr: 2.179 ± 0.041
0.0PheXaa: 0.0 ± 0.0
Gly
4.23GlyAla: 4.23 ± 0.062
0.726GlyCys: 0.726 ± 0.031
3.716GlyAsp: 3.716 ± 0.057
4.041GlyGlu: 4.041 ± 0.047
3.454GlyPhe: 3.454 ± 0.052
4.735GlyGly: 4.735 ± 0.09
1.252GlyHis: 1.252 ± 0.028
5.439GlyIle: 5.439 ± 0.073
4.911GlyLys: 4.911 ± 0.06
5.938GlyLeu: 5.938 ± 0.072
1.819GlyMet: 1.819 ± 0.032
3.572GlyAsn: 3.572 ± 0.049
1.382GlyPro: 1.382 ± 0.035
2.082GlyGln: 2.082 ± 0.04
2.414GlyArg: 2.414 ± 0.039
4.213GlySer: 4.213 ± 0.074
3.811GlyThr: 3.811 ± 0.063
4.839GlyVal: 4.839 ± 0.064
0.893GlyTrp: 0.893 ± 0.026
3.098GlyTyr: 3.098 ± 0.051
0.0GlyXaa: 0.0 ± 0.0
His
1.119HisAla: 1.119 ± 0.025
0.219HisCys: 0.219 ± 0.013
0.965HisAsp: 0.965 ± 0.028
1.11HisGlu: 1.11 ± 0.027
1.211HisPhe: 1.211 ± 0.029
1.222HisGly: 1.222 ± 0.03
0.664HisHis: 0.664 ± 0.022
1.644HisIle: 1.644 ± 0.031
1.442HisLys: 1.442 ± 0.034
2.011HisLeu: 2.011 ± 0.037
0.508HisMet: 0.508 ± 0.019
1.038HisAsn: 1.038 ± 0.027
1.018HisPro: 1.018 ± 0.028
0.841HisGln: 0.841 ± 0.02
0.776HisArg: 0.776 ± 0.024
1.279HisSer: 1.279 ± 0.03
1.037HisThr: 1.037 ± 0.025
1.101HisVal: 1.101 ± 0.029
0.283HisTrp: 0.283 ± 0.014
0.923HisTyr: 0.923 ± 0.023
0.0HisXaa: 0.0 ± 0.0
Ile
4.883IleAla: 4.883 ± 0.067
0.752IleCys: 0.752 ± 0.023
4.659IleAsp: 4.659 ± 0.059
5.168IleGlu: 5.168 ± 0.06
3.323IlePhe: 3.323 ± 0.054
4.816IleGly: 4.816 ± 0.064
1.653IleHis: 1.653 ± 0.036
5.39IleIle: 5.39 ± 0.076
5.509IleLys: 5.509 ± 0.069
6.466IleLeu: 6.466 ± 0.069
1.51IleMet: 1.51 ± 0.03
4.387IleAsn: 4.387 ± 0.058
3.186IlePro: 3.186 ± 0.041
2.625IleGln: 2.625 ± 0.041
3.037IleArg: 3.037 ± 0.045
5.707IleSer: 5.707 ± 0.056
4.212IleThr: 4.212 ± 0.067
4.593IleVal: 4.593 ± 0.053
0.877IleTrp: 0.877 ± 0.027
2.936IleTyr: 2.936 ± 0.049
0.0IleXaa: 0.0 ± 0.0
Lys
4.716LysAla: 4.716 ± 0.068
0.504LysCys: 0.504 ± 0.021
4.305LysAsp: 4.305 ± 0.057
5.958LysGlu: 5.958 ± 0.077
2.513LysPhe: 2.513 ± 0.041
4.841LysGly: 4.841 ± 0.054
1.473LysHis: 1.473 ± 0.03
5.429LysIle: 5.429 ± 0.067
6.149LysLys: 6.149 ± 0.067
6.215LysLeu: 6.215 ± 0.071
2.123LysMet: 2.123 ± 0.037
4.643LysAsn: 4.643 ± 0.064
2.326LysPro: 2.326 ± 0.039
2.699LysGln: 2.699 ± 0.041
3.041LysArg: 3.041 ± 0.049
4.344LysSer: 4.344 ± 0.049
3.825LysThr: 3.825 ± 0.053
4.893LysVal: 4.893 ± 0.061
0.871LysTrp: 0.871 ± 0.028
3.424LysTyr: 3.424 ± 0.051
0.0LysXaa: 0.0 ± 0.0
Leu
5.605LeuAla: 5.605 ± 0.071
0.878LeuCys: 0.878 ± 0.022
4.837LeuAsp: 4.837 ± 0.05
5.29LeuGlu: 5.29 ± 0.073
4.589LeuPhe: 4.589 ± 0.063
5.628LeuGly: 5.628 ± 0.069
1.715LeuHis: 1.715 ± 0.035
6.33LeuIle: 6.33 ± 0.075
7.472LeuLys: 7.472 ± 0.081
8.657LeuLeu: 8.657 ± 0.093
2.426LeuMet: 2.426 ± 0.045
5.396LeuAsn: 5.396 ± 0.059
3.519LeuPro: 3.519 ± 0.052
3.087LeuGln: 3.087 ± 0.042
3.373LeuArg: 3.373 ± 0.053
7.047LeuSer: 7.047 ± 0.073
4.72LeuThr: 4.72 ± 0.059
5.495LeuVal: 5.495 ± 0.065
1.014LeuTrp: 1.014 ± 0.029
3.362LeuTyr: 3.362 ± 0.045
0.0LeuXaa: 0.0 ± 0.0
Met
1.968MetAla: 1.968 ± 0.037
0.206MetCys: 0.206 ± 0.011
1.627MetAsp: 1.627 ± 0.032
1.616MetGlu: 1.616 ± 0.032
0.935MetPhe: 0.935 ± 0.028
1.891MetGly: 1.891 ± 0.037
0.508MetHis: 0.508 ± 0.016
1.755MetIle: 1.755 ± 0.038
2.176MetLys: 2.176 ± 0.038
2.169MetLeu: 2.169 ± 0.042
0.738MetMet: 0.738 ± 0.022
1.458MetAsn: 1.458 ± 0.031
1.032MetPro: 1.032 ± 0.027
0.894MetGln: 0.894 ± 0.022
0.991MetArg: 0.991 ± 0.023
1.5MetSer: 1.5 ± 0.025
1.169MetThr: 1.169 ± 0.025
1.839MetVal: 1.839 ± 0.039
0.258MetTrp: 0.258 ± 0.014
0.857MetTyr: 0.857 ± 0.024
0.0MetXaa: 0.0 ± 0.0
Asn
3.443AsnAla: 3.443 ± 0.049
0.501AsnCys: 0.501 ± 0.018
3.096AsnAsp: 3.096 ± 0.043
3.481AsnGlu: 3.481 ± 0.043
2.402AsnPhe: 2.402 ± 0.039
4.097AsnGly: 4.097 ± 0.062
1.212AsnHis: 1.212 ± 0.029
4.692AsnIle: 4.692 ± 0.055
4.393AsnLys: 4.393 ± 0.06
4.627AsnLeu: 4.627 ± 0.057
1.436AsnMet: 1.436 ± 0.031
3.652AsnAsn: 3.652 ± 0.064
2.481AsnPro: 2.481 ± 0.046
2.054AsnGln: 2.054 ± 0.038
2.251AsnArg: 2.251 ± 0.041
3.496AsnSer: 3.496 ± 0.056
3.322AsnThr: 3.322 ± 0.044
3.254AsnVal: 3.254 ± 0.047
0.746AsnTrp: 0.746 ± 0.023
2.76AsnTyr: 2.76 ± 0.047
0.0AsnXaa: 0.0 ± 0.0
Pro
2.112ProAla: 2.112 ± 0.043
0.258ProCys: 0.258 ± 0.013
2.259ProAsp: 2.259 ± 0.043
2.744ProGlu: 2.744 ± 0.04
1.793ProPhe: 1.793 ± 0.03
2.17ProGly: 2.17 ± 0.037
0.767ProHis: 0.767 ± 0.023
2.493ProIle: 2.493 ± 0.044
2.098ProLys: 2.098 ± 0.036
3.03ProLeu: 3.03 ± 0.047
0.819ProMet: 0.819 ± 0.023
1.927ProAsn: 1.927 ± 0.034
0.861ProPro: 0.861 ± 0.026
1.365ProGln: 1.365 ± 0.031
1.038ProArg: 1.038 ± 0.026
2.27ProSer: 2.27 ± 0.044
1.827ProThr: 1.827 ± 0.036
2.523ProVal: 2.523 ± 0.044
0.406ProTrp: 0.406 ± 0.016
1.611ProTyr: 1.611 ± 0.036
0.0ProXaa: 0.0 ± 0.0
Gln
2.219GlnAla: 2.219 ± 0.038
0.243GlnCys: 0.243 ± 0.014
1.745GlnAsp: 1.745 ± 0.035
2.384GlnGlu: 2.384 ± 0.042
1.565GlnPhe: 1.565 ± 0.029
2.039GlnGly: 2.039 ± 0.037
0.716GlnHis: 0.716 ± 0.021
2.538GlnIle: 2.538 ± 0.044
2.878GlnLys: 2.878 ± 0.04
3.614GlnLeu: 3.614 ± 0.05
0.94GlnMet: 0.94 ± 0.023
1.963GlnAsn: 1.963 ± 0.032
1.009GlnPro: 1.009 ± 0.025
1.535GlnGln: 1.535 ± 0.034
1.438GlnArg: 1.438 ± 0.032
2.202GlnSer: 2.202 ± 0.035
1.827GlnThr: 1.827 ± 0.032
2.176GlnVal: 2.176 ± 0.036
0.523GlnTrp: 0.523 ± 0.018
1.473GlnTyr: 1.473 ± 0.03
0.0GlnXaa: 0.0 ± 0.0
Arg
2.1ArgAla: 2.1 ± 0.037
0.309ArgCys: 0.309 ± 0.012
1.955ArgAsp: 1.955 ± 0.035
2.308ArgGlu: 2.308 ± 0.039
2.083ArgPhe: 2.083 ± 0.034
2.119ArgGly: 2.119 ± 0.04
0.709ArgHis: 0.709 ± 0.022
3.063ArgIle: 3.063 ± 0.044
2.987ArgLys: 2.987 ± 0.048
3.572ArgLeu: 3.572 ± 0.053
1.19ArgMet: 1.19 ± 0.031
2.215ArgAsn: 2.215 ± 0.039
1.253ArgPro: 1.253 ± 0.029
1.241ArgGln: 1.241 ± 0.028
1.509ArgArg: 1.509 ± 0.033
2.195ArgSer: 2.195 ± 0.041
1.933ArgThr: 1.933 ± 0.033
2.393ArgVal: 2.393 ± 0.039
0.557ArgTrp: 0.557 ± 0.019
1.856ArgTyr: 1.856 ± 0.032
0.0ArgXaa: 0.0 ± 0.0
Ser
4.005SerAla: 4.005 ± 0.058
0.712SerCys: 0.712 ± 0.023
3.83SerAsp: 3.83 ± 0.052
3.92SerGlu: 3.92 ± 0.056
3.855SerPhe: 3.855 ± 0.064
4.748SerGly: 4.748 ± 0.074
1.345SerHis: 1.345 ± 0.03
5.244SerIle: 5.244 ± 0.061
4.521SerLys: 4.521 ± 0.057
6.207SerLeu: 6.207 ± 0.064
1.604SerMet: 1.604 ± 0.03
3.722SerAsn: 3.722 ± 0.055
2.301SerPro: 2.301 ± 0.039
2.208SerGln: 2.208 ± 0.036
2.328SerArg: 2.328 ± 0.042
4.763SerSer: 4.763 ± 0.075
3.449SerThr: 3.449 ± 0.056
4.276SerVal: 4.276 ± 0.055
0.835SerTrp: 0.835 ± 0.023
3.186SerTyr: 3.186 ± 0.057
0.0SerXaa: 0.0 ± 0.0
Thr
3.308ThrAla: 3.308 ± 0.057
0.437ThrCys: 0.437 ± 0.017
2.999ThrAsp: 2.999 ± 0.05
3.027ThrGlu: 3.027 ± 0.045
2.495ThrPhe: 2.495 ± 0.046
3.952ThrGly: 3.952 ± 0.061
1.2ThrHis: 1.2 ± 0.029
4.343ThrIle: 4.343 ± 0.063
3.307ThrLys: 3.307 ± 0.046
4.61ThrLeu: 4.61 ± 0.053
1.113ThrMet: 1.113 ± 0.026
2.804ThrAsn: 2.804 ± 0.049
2.286ThrPro: 2.286 ± 0.04
1.852ThrGln: 1.852 ± 0.036
1.699ThrArg: 1.699 ± 0.034
3.583ThrSer: 3.583 ± 0.052
2.933ThrThr: 2.933 ± 0.053
3.45ThrVal: 3.45 ± 0.073
0.649ThrTrp: 0.649 ± 0.026
2.286ThrTyr: 2.286 ± 0.047
0.0ThrXaa: 0.0 ± 0.0
Val
4.011ValAla: 4.011 ± 0.06
0.667ValCys: 0.667 ± 0.025
3.95ValAsp: 3.95 ± 0.048
4.12ValGlu: 4.12 ± 0.057
3.353ValPhe: 3.353 ± 0.046
4.081ValGly: 4.081 ± 0.054
1.16ValHis: 1.16 ± 0.027
4.763ValIle: 4.763 ± 0.058
4.592ValLys: 4.592 ± 0.063
6.012ValLeu: 6.012 ± 0.08
1.573ValMet: 1.573 ± 0.033
3.656ValAsn: 3.656 ± 0.056
2.276ValPro: 2.276 ± 0.041
1.975ValGln: 1.975 ± 0.036
2.383ValArg: 2.383 ± 0.041
4.877ValSer: 4.877 ± 0.069
3.239ValThr: 3.239 ± 0.065
4.594ValVal: 4.594 ± 0.068
0.74ValTrp: 0.74 ± 0.021
2.59ValTyr: 2.59 ± 0.045
0.0ValXaa: 0.0 ± 0.0
Trp
0.715TrpAla: 0.715 ± 0.021
0.133TrpCys: 0.133 ± 0.009
0.779TrpAsp: 0.779 ± 0.025
0.777TrpGlu: 0.777 ± 0.022
0.601TrpPhe: 0.601 ± 0.023
0.929TrpGly: 0.929 ± 0.027
0.29TrpHis: 0.29 ± 0.015
0.877TrpIle: 0.877 ± 0.029
0.877TrpLys: 0.877 ± 0.025
1.136TrpLeu: 1.136 ± 0.028
0.381TrpMet: 0.381 ± 0.016
0.756TrpAsn: 0.756 ± 0.024
0.36TrpPro: 0.36 ± 0.016
0.483TrpGln: 0.483 ± 0.02
0.493TrpArg: 0.493 ± 0.017
0.822TrpSer: 0.822 ± 0.023
0.637TrpThr: 0.637 ± 0.024
0.803TrpVal: 0.803 ± 0.022
0.206TrpTrp: 0.206 ± 0.012
0.534TrpTyr: 0.534 ± 0.02
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.73TyrAla: 2.73 ± 0.047
0.477TyrCys: 0.477 ± 0.018
2.535TyrAsp: 2.535 ± 0.046
2.41TyrGlu: 2.41 ± 0.045
2.366TyrPhe: 2.366 ± 0.038
2.979TyrGly: 2.979 ± 0.048
1.015TyrHis: 1.015 ± 0.025
2.763TyrIle: 2.763 ± 0.042
3.076TyrLys: 3.076 ± 0.047
4.062TyrLeu: 4.062 ± 0.063
1.007TyrMet: 1.007 ± 0.026
2.636TyrAsn: 2.636 ± 0.048
1.68TyrPro: 1.68 ± 0.037
1.703TyrGln: 1.703 ± 0.032
1.901TyrArg: 1.901 ± 0.035
3.095TyrSer: 3.095 ± 0.054
2.474TyrThr: 2.474 ± 0.052
2.359TyrVal: 2.359 ± 0.04
0.62TyrTrp: 0.62 ± 0.021
2.22TyrTyr: 2.22 ± 0.05
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4663 proteins (1609379 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski