Amino acid dipepetide frequency for Pasteurella virus F108

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.132AlaAla: 4.132 ± 0.899
1.033AlaCys: 1.033 ± 0.346
3.558AlaAsp: 3.558 ± 0.743
6.657AlaGlu: 6.657 ± 1.052
3.329AlaPhe: 3.329 ± 0.586
4.821AlaGly: 4.821 ± 0.997
1.722AlaHis: 1.722 ± 0.442
5.969AlaIle: 5.969 ± 0.945
5.969AlaLys: 5.969 ± 0.928
7.461AlaLeu: 7.461 ± 1.36
1.951AlaMet: 1.951 ± 0.392
3.673AlaAsn: 3.673 ± 0.551
2.87AlaPro: 2.87 ± 0.712
5.051AlaGln: 5.051 ± 0.628
3.673AlaArg: 3.673 ± 0.587
3.903AlaSer: 3.903 ± 0.509
5.051AlaThr: 5.051 ± 0.64
5.051AlaVal: 5.051 ± 0.856
1.033AlaTrp: 1.033 ± 0.265
2.87AlaTyr: 2.87 ± 0.515
0.0AlaXaa: 0.0 ± 0.0
Cys
0.918CysAla: 0.918 ± 0.351
0.0CysCys: 0.0 ± 0.0
0.574CysAsp: 0.574 ± 0.25
0.574CysGlu: 0.574 ± 0.261
0.574CysPhe: 0.574 ± 0.236
0.918CysGly: 0.918 ± 0.281
0.115CysHis: 0.115 ± 0.125
0.344CysIle: 0.344 ± 0.248
0.574CysLys: 0.574 ± 0.3
1.033CysLeu: 1.033 ± 0.456
0.115CysMet: 0.115 ± 0.121
0.574CysAsn: 0.574 ± 0.268
0.344CysPro: 0.344 ± 0.185
0.0CysGln: 0.0 ± 0.0
0.689CysArg: 0.689 ± 0.27
0.459CysSer: 0.459 ± 0.24
0.344CysThr: 0.344 ± 0.21
0.918CysVal: 0.918 ± 0.244
0.115CysTrp: 0.115 ± 0.115
0.574CysTyr: 0.574 ± 0.26
0.0CysXaa: 0.0 ± 0.0
Asp
3.329AspAla: 3.329 ± 0.666
0.23AspCys: 0.23 ± 0.164
3.444AspAsp: 3.444 ± 0.498
3.903AspGlu: 3.903 ± 0.583
3.558AspPhe: 3.558 ± 0.586
4.017AspGly: 4.017 ± 0.646
0.689AspHis: 0.689 ± 0.222
3.444AspIle: 3.444 ± 0.695
4.017AspLys: 4.017 ± 0.923
5.165AspLeu: 5.165 ± 0.898
0.918AspMet: 0.918 ± 0.29
2.181AspAsn: 2.181 ± 0.547
2.755AspPro: 2.755 ± 0.505
2.181AspGln: 2.181 ± 0.534
2.296AspArg: 2.296 ± 0.471
3.329AspSer: 3.329 ± 0.625
2.066AspThr: 2.066 ± 0.434
3.558AspVal: 3.558 ± 0.672
0.23AspTrp: 0.23 ± 0.147
2.755AspTyr: 2.755 ± 0.549
0.0AspXaa: 0.0 ± 0.0
Glu
2.181GluAla: 2.181 ± 0.54
0.689GluCys: 0.689 ± 0.285
3.788GluAsp: 3.788 ± 0.73
3.673GluGlu: 3.673 ± 0.873
2.984GluPhe: 2.984 ± 0.588
2.41GluGly: 2.41 ± 0.501
1.607GluHis: 1.607 ± 0.382
6.887GluIle: 6.887 ± 1.16
6.657GluLys: 6.657 ± 0.887
6.198GluLeu: 6.198 ± 0.715
2.64GluMet: 2.64 ± 0.516
5.395GluAsn: 5.395 ± 0.955
1.263GluPro: 1.263 ± 0.343
4.706GluGln: 4.706 ± 0.822
4.706GluArg: 4.706 ± 0.716
3.214GluSer: 3.214 ± 0.582
2.87GluThr: 2.87 ± 0.637
3.903GluVal: 3.903 ± 0.676
0.459GluTrp: 0.459 ± 0.213
2.181GluTyr: 2.181 ± 0.382
0.0GluXaa: 0.0 ± 0.0
Phe
3.903PheAla: 3.903 ± 0.587
0.344PheCys: 0.344 ± 0.191
2.64PheAsp: 2.64 ± 0.592
3.329PheGlu: 3.329 ± 0.546
1.951PhePhe: 1.951 ± 0.579
3.214PheGly: 3.214 ± 0.733
0.459PheHis: 0.459 ± 0.241
3.558PheIle: 3.558 ± 0.667
2.525PheLys: 2.525 ± 0.641
3.673PheLeu: 3.673 ± 0.64
0.803PheMet: 0.803 ± 0.295
3.329PheAsn: 3.329 ± 0.843
1.377PhePro: 1.377 ± 0.355
1.033PheGln: 1.033 ± 0.358
2.066PheArg: 2.066 ± 0.482
3.214PheSer: 3.214 ± 0.737
3.214PheThr: 3.214 ± 0.688
3.788PheVal: 3.788 ± 0.757
0.459PheTrp: 0.459 ± 0.165
1.607PheTyr: 1.607 ± 0.443
0.0PheXaa: 0.0 ± 0.0
Gly
5.51GlyAla: 5.51 ± 0.798
0.574GlyCys: 0.574 ± 0.326
4.132GlyAsp: 4.132 ± 0.74
4.821GlyGlu: 4.821 ± 0.843
2.181GlyPhe: 2.181 ± 0.493
4.017GlyGly: 4.017 ± 0.621
0.918GlyHis: 0.918 ± 0.313
4.477GlyIle: 4.477 ± 0.67
4.706GlyLys: 4.706 ± 0.933
4.362GlyLeu: 4.362 ± 0.946
1.837GlyMet: 1.837 ± 0.421
4.247GlyAsn: 4.247 ± 0.877
0.459GlyPro: 0.459 ± 0.3
1.837GlyGln: 1.837 ± 0.456
2.41GlyArg: 2.41 ± 0.663
3.214GlySer: 3.214 ± 0.748
3.558GlyThr: 3.558 ± 0.724
5.395GlyVal: 5.395 ± 1.2
0.803GlyTrp: 0.803 ± 0.272
1.263GlyTyr: 1.263 ± 0.374
0.0GlyXaa: 0.0 ± 0.0
His
1.722HisAla: 1.722 ± 0.463
0.803HisCys: 0.803 ± 0.313
1.377HisAsp: 1.377 ± 0.359
0.689HisGlu: 0.689 ± 0.235
1.033HisPhe: 1.033 ± 0.369
0.918HisGly: 0.918 ± 0.275
0.344HisHis: 0.344 ± 0.159
1.033HisIle: 1.033 ± 0.302
1.033HisLys: 1.033 ± 0.397
1.607HisLeu: 1.607 ± 0.458
0.459HisMet: 0.459 ± 0.258
1.263HisAsn: 1.263 ± 0.552
0.23HisPro: 0.23 ± 0.15
0.23HisGln: 0.23 ± 0.136
0.689HisArg: 0.689 ± 0.234
1.148HisSer: 1.148 ± 0.284
0.689HisThr: 0.689 ± 0.244
0.803HisVal: 0.803 ± 0.345
0.344HisTrp: 0.344 ± 0.17
0.803HisTyr: 0.803 ± 0.286
0.0HisXaa: 0.0 ± 0.0
Ile
7.92IleAla: 7.92 ± 1.192
0.803IleCys: 0.803 ± 0.313
4.936IleAsp: 4.936 ± 0.712
6.428IleGlu: 6.428 ± 0.881
3.099IlePhe: 3.099 ± 0.722
4.821IleGly: 4.821 ± 1.049
1.377IleHis: 1.377 ± 0.351
4.017IleIle: 4.017 ± 0.71
6.198IleLys: 6.198 ± 0.71
4.936IleLeu: 4.936 ± 0.682
0.23IleMet: 0.23 ± 0.165
5.624IleAsn: 5.624 ± 0.899
2.755IlePro: 2.755 ± 0.557
2.755IleGln: 2.755 ± 0.702
4.132IleArg: 4.132 ± 0.627
3.558IleSer: 3.558 ± 0.607
4.936IleThr: 4.936 ± 0.82
3.329IleVal: 3.329 ± 0.607
0.459IleTrp: 0.459 ± 0.252
2.066IleTyr: 2.066 ± 0.452
0.0IleXaa: 0.0 ± 0.0
Lys
6.657LysAla: 6.657 ± 1.006
0.803LysCys: 0.803 ± 0.255
3.903LysAsp: 3.903 ± 0.699
5.395LysGlu: 5.395 ± 0.947
2.87LysPhe: 2.87 ± 0.584
3.903LysGly: 3.903 ± 0.692
1.722LysHis: 1.722 ± 0.539
5.165LysIle: 5.165 ± 0.783
6.657LysLys: 6.657 ± 1.061
6.084LysLeu: 6.084 ± 0.754
2.64LysMet: 2.64 ± 0.574
3.673LysAsn: 3.673 ± 0.678
2.181LysPro: 2.181 ± 0.541
3.673LysGln: 3.673 ± 0.546
4.821LysArg: 4.821 ± 0.794
6.428LysSer: 6.428 ± 0.876
6.772LysThr: 6.772 ± 0.942
4.132LysVal: 4.132 ± 0.649
2.181LysTrp: 2.181 ± 0.524
2.87LysTyr: 2.87 ± 0.666
0.0LysXaa: 0.0 ± 0.0
Leu
6.772LeuAla: 6.772 ± 0.904
0.803LeuCys: 0.803 ± 0.32
4.362LeuAsp: 4.362 ± 0.778
5.051LeuGlu: 5.051 ± 0.73
4.706LeuPhe: 4.706 ± 0.558
3.099LeuGly: 3.099 ± 0.744
0.689LeuHis: 0.689 ± 0.25
8.035LeuIle: 8.035 ± 1.127
6.887LeuLys: 6.887 ± 1.113
6.887LeuLeu: 6.887 ± 0.837
1.837LeuMet: 1.837 ± 0.476
6.428LeuAsn: 6.428 ± 0.752
3.788LeuPro: 3.788 ± 0.907
2.755LeuGln: 2.755 ± 0.563
3.788LeuArg: 3.788 ± 0.615
5.739LeuSer: 5.739 ± 0.723
5.969LeuThr: 5.969 ± 1.122
3.444LeuVal: 3.444 ± 0.685
0.344LeuTrp: 0.344 ± 0.151
2.066LeuTyr: 2.066 ± 0.493
0.0LeuXaa: 0.0 ± 0.0
Met
1.722MetAla: 1.722 ± 0.473
0.344MetCys: 0.344 ± 0.172
0.459MetAsp: 0.459 ± 0.212
0.689MetGlu: 0.689 ± 0.336
1.377MetPhe: 1.377 ± 0.351
1.263MetGly: 1.263 ± 0.308
0.344MetHis: 0.344 ± 0.203
2.296MetIle: 2.296 ± 0.479
2.066MetLys: 2.066 ± 0.476
1.951MetLeu: 1.951 ± 0.474
0.344MetMet: 0.344 ± 0.176
1.148MetAsn: 1.148 ± 0.335
0.803MetPro: 0.803 ± 0.371
0.918MetGln: 0.918 ± 0.304
1.492MetArg: 1.492 ± 0.389
1.492MetSer: 1.492 ± 0.358
1.607MetThr: 1.607 ± 0.367
0.574MetVal: 0.574 ± 0.264
0.689MetTrp: 0.689 ± 0.245
0.344MetTyr: 0.344 ± 0.179
0.0MetXaa: 0.0 ± 0.0
Asn
4.706AsnAla: 4.706 ± 0.74
0.689AsnCys: 0.689 ± 0.243
2.64AsnAsp: 2.64 ± 0.62
3.558AsnGlu: 3.558 ± 0.625
2.296AsnPhe: 2.296 ± 0.566
4.132AsnGly: 4.132 ± 0.583
0.689AsnHis: 0.689 ± 0.236
4.936AsnIle: 4.936 ± 0.773
5.165AsnLys: 5.165 ± 0.822
4.706AsnLeu: 4.706 ± 0.763
1.722AsnMet: 1.722 ± 0.266
2.64AsnAsn: 2.64 ± 0.578
2.525AsnPro: 2.525 ± 0.551
2.64AsnGln: 2.64 ± 0.58
2.984AsnArg: 2.984 ± 0.585
2.64AsnSer: 2.64 ± 0.586
3.214AsnThr: 3.214 ± 0.526
2.87AsnVal: 2.87 ± 0.581
1.148AsnTrp: 1.148 ± 0.336
1.148AsnTyr: 1.148 ± 0.359
0.0AsnXaa: 0.0 ± 0.0
Pro
3.444ProAla: 3.444 ± 0.681
0.23ProCys: 0.23 ± 0.174
1.837ProAsp: 1.837 ± 0.5
2.41ProGlu: 2.41 ± 0.47
2.296ProPhe: 2.296 ± 0.495
1.377ProGly: 1.377 ± 0.451
0.689ProHis: 0.689 ± 0.29
2.41ProIle: 2.41 ± 0.497
2.296ProLys: 2.296 ± 0.462
2.64ProLeu: 2.64 ± 0.518
0.23ProMet: 0.23 ± 0.16
1.837ProAsn: 1.837 ± 0.41
1.148ProPro: 1.148 ± 0.318
0.918ProGln: 0.918 ± 0.383
1.837ProArg: 1.837 ± 0.495
1.722ProSer: 1.722 ± 0.556
1.033ProThr: 1.033 ± 0.306
1.722ProVal: 1.722 ± 0.445
0.574ProTrp: 0.574 ± 0.215
0.689ProTyr: 0.689 ± 0.277
0.0ProXaa: 0.0 ± 0.0
Gln
3.329GlnAla: 3.329 ± 0.6
0.115GlnCys: 0.115 ± 0.111
2.181GlnAsp: 2.181 ± 0.489
3.673GlnGlu: 3.673 ± 0.438
2.181GlnPhe: 2.181 ± 0.462
2.296GlnGly: 2.296 ± 0.463
0.689GlnHis: 0.689 ± 0.243
3.788GlnIle: 3.788 ± 0.678
4.706GlnLys: 4.706 ± 0.695
3.329GlnLeu: 3.329 ± 0.716
0.803GlnMet: 0.803 ± 0.31
1.837GlnAsn: 1.837 ± 0.408
0.918GlnPro: 0.918 ± 0.318
2.525GlnGln: 2.525 ± 0.477
2.64GlnArg: 2.64 ± 0.631
2.181GlnSer: 2.181 ± 0.397
1.951GlnThr: 1.951 ± 0.453
2.64GlnVal: 2.64 ± 0.47
0.459GlnTrp: 0.459 ± 0.183
0.689GlnTyr: 0.689 ± 0.263
0.0GlnXaa: 0.0 ± 0.0
Arg
4.362ArgAla: 4.362 ± 0.801
0.344ArgCys: 0.344 ± 0.181
3.329ArgAsp: 3.329 ± 0.556
4.362ArgGlu: 4.362 ± 0.642
2.066ArgPhe: 2.066 ± 0.531
2.984ArgGly: 2.984 ± 0.538
0.689ArgHis: 0.689 ± 0.325
3.673ArgIle: 3.673 ± 0.659
4.477ArgLys: 4.477 ± 0.81
4.477ArgLeu: 4.477 ± 1.082
0.689ArgMet: 0.689 ± 0.27
3.444ArgAsn: 3.444 ± 0.639
1.377ArgPro: 1.377 ± 0.45
2.181ArgGln: 2.181 ± 0.531
3.558ArgArg: 3.558 ± 0.712
2.41ArgSer: 2.41 ± 0.43
3.329ArgThr: 3.329 ± 0.518
3.329ArgVal: 3.329 ± 0.542
0.459ArgTrp: 0.459 ± 0.201
1.951ArgTyr: 1.951 ± 0.408
0.0ArgXaa: 0.0 ± 0.0
Ser
5.854SerAla: 5.854 ± 1.032
0.459SerCys: 0.459 ± 0.266
2.296SerAsp: 2.296 ± 0.491
3.329SerGlu: 3.329 ± 0.582
2.64SerPhe: 2.64 ± 0.63
5.51SerGly: 5.51 ± 0.695
1.837SerHis: 1.837 ± 0.528
2.984SerIle: 2.984 ± 0.491
4.477SerLys: 4.477 ± 0.772
5.51SerLeu: 5.51 ± 0.66
1.033SerMet: 1.033 ± 0.353
3.099SerAsn: 3.099 ± 0.587
1.722SerPro: 1.722 ± 0.412
1.607SerGln: 1.607 ± 0.345
2.525SerArg: 2.525 ± 0.529
3.673SerSer: 3.673 ± 0.687
3.099SerThr: 3.099 ± 0.653
4.017SerVal: 4.017 ± 0.757
0.459SerTrp: 0.459 ± 0.23
1.951SerTyr: 1.951 ± 0.48
0.0SerXaa: 0.0 ± 0.0
Thr
4.017ThrAla: 4.017 ± 0.645
0.574ThrCys: 0.574 ± 0.266
4.132ThrAsp: 4.132 ± 0.628
2.87ThrGlu: 2.87 ± 0.551
2.066ThrPhe: 2.066 ± 0.414
3.673ThrGly: 3.673 ± 0.675
1.148ThrHis: 1.148 ± 0.32
4.132ThrIle: 4.132 ± 0.681
4.936ThrLys: 4.936 ± 0.608
4.821ThrLeu: 4.821 ± 0.61
1.722ThrMet: 1.722 ± 0.353
2.296ThrAsn: 2.296 ± 0.543
2.41ThrPro: 2.41 ± 0.456
3.444ThrGln: 3.444 ± 0.626
2.64ThrArg: 2.64 ± 0.569
3.558ThrSer: 3.558 ± 0.699
2.181ThrThr: 2.181 ± 0.513
3.444ThrVal: 3.444 ± 0.636
1.033ThrTrp: 1.033 ± 0.353
1.951ThrTyr: 1.951 ± 0.482
0.0ThrXaa: 0.0 ± 0.0
Val
5.395ValAla: 5.395 ± 0.798
0.574ValCys: 0.574 ± 0.247
2.41ValAsp: 2.41 ± 0.459
4.706ValGlu: 4.706 ± 0.676
1.722ValPhe: 1.722 ± 0.45
3.558ValGly: 3.558 ± 1.011
0.803ValHis: 0.803 ± 0.25
4.247ValIle: 4.247 ± 0.732
5.854ValLys: 5.854 ± 0.836
4.362ValLeu: 4.362 ± 0.598
1.263ValMet: 1.263 ± 0.471
2.87ValAsn: 2.87 ± 0.607
1.837ValPro: 1.837 ± 0.483
1.722ValGln: 1.722 ± 0.337
3.903ValArg: 3.903 ± 0.67
3.558ValSer: 3.558 ± 0.75
3.788ValThr: 3.788 ± 0.656
2.87ValVal: 2.87 ± 0.978
0.574ValTrp: 0.574 ± 0.264
1.837ValTyr: 1.837 ± 0.369
0.0ValXaa: 0.0 ± 0.0
Trp
1.607TrpAla: 1.607 ± 0.461
0.0TrpCys: 0.0 ± 0.0
0.459TrpAsp: 0.459 ± 0.268
0.689TrpGlu: 0.689 ± 0.26
0.803TrpPhe: 0.803 ± 0.329
0.918TrpGly: 0.918 ± 0.31
0.115TrpHis: 0.115 ± 0.1
0.803TrpIle: 0.803 ± 0.275
0.803TrpLys: 0.803 ± 0.274
1.492TrpLeu: 1.492 ± 0.556
0.23TrpMet: 0.23 ± 0.154
0.23TrpAsn: 0.23 ± 0.14
0.0TrpPro: 0.0 ± 0.0
0.918TrpGln: 0.918 ± 0.248
0.918TrpArg: 0.918 ± 0.466
0.918TrpSer: 0.918 ± 0.292
0.344TrpThr: 0.344 ± 0.16
0.574TrpVal: 0.574 ± 0.266
0.23TrpTrp: 0.23 ± 0.173
0.23TrpTyr: 0.23 ± 0.178
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.296TyrAla: 2.296 ± 0.621
0.344TyrCys: 0.344 ± 0.273
1.607TyrAsp: 1.607 ± 0.382
1.607TyrGlu: 1.607 ± 0.458
2.755TyrPhe: 2.755 ± 0.749
2.87TyrGly: 2.87 ± 0.598
0.574TyrHis: 0.574 ± 0.231
2.181TyrIle: 2.181 ± 0.692
2.525TyrLys: 2.525 ± 0.564
2.755TyrLeu: 2.755 ± 0.557
0.344TyrMet: 0.344 ± 0.182
1.263TyrAsn: 1.263 ± 0.341
0.574TyrPro: 0.574 ± 0.26
1.837TyrGln: 1.837 ± 0.407
1.837TyrArg: 1.837 ± 0.513
1.722TyrSer: 1.722 ± 0.492
1.033TyrThr: 1.033 ± 0.329
1.492TyrVal: 1.492 ± 0.312
0.23TyrTrp: 0.23 ± 0.137
1.377TyrTyr: 1.377 ± 0.368
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 44 proteins (8713 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski