Amino acid dipepetide frequency for Lasius niger (Black garden ant)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.082AlaAla: 6.082 ± 0.066	1.162AlaCys: 1.162 ± 0.017	3.551AlaAsp: 3.551 ± 0.03	4.486AlaGlu: 4.486 ± 0.03	2.281AlaPhe: 2.281 ± 0.023	3.753AlaGly: 3.753 ± 0.032	1.412AlaHis: 1.412 ± 0.014	3.842AlaIle: 3.842 ± 0.029	4.134AlaLys: 4.134 ± 0.028	6.105AlaLeu: 6.105 ± 0.039	1.604AlaMet: 1.604 ± 0.015	2.935AlaAsn: 2.935 ± 0.021	3.018AlaPro: 3.018 ± 0.028	2.587AlaGln: 2.587 ± 0.021	3.935AlaArg: 3.935 ± 0.028	5.074AlaSer: 5.074 ± 0.034	4.168AlaThr: 4.168 ± 0.027	4.338AlaVal: 4.338 ± 0.03	0.727AlaTrp: 0.727 ± 0.011	1.747AlaTyr: 1.747 ± 0.019	0.0AlaXaa: 0.0 ± 0.0
Cys	1.068CysAla: 1.068 ± 0.014	0.356CysCys: 0.356 ± 0.009	1.064CysAsp: 1.064 ± 0.016	1.126CysGlu: 1.126 ± 0.018	0.681CysPhe: 0.681 ± 0.01	1.232CysGly: 1.232 ± 0.018	0.448CysHis: 0.448 ± 0.01	0.977CysIle: 0.977 ± 0.013	1.08CysLys: 1.08 ± 0.015	1.684CysLeu: 1.684 ± 0.02	0.354CysMet: 0.354 ± 0.008	0.865CysAsn: 0.865 ± 0.013	0.935CysPro: 0.935 ± 0.018	0.681CysGln: 0.681 ± 0.012	1.049CysArg: 1.049 ± 0.015	1.284CysSer: 1.284 ± 0.018	0.972CysThr: 0.972 ± 0.014	1.088CysVal: 1.088 ± 0.015	0.221CysTrp: 0.221 ± 0.006	0.53CysTyr: 0.53 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	3.721AspAla: 3.721 ± 0.027	0.997AspCys: 0.997 ± 0.015	4.145AspAsp: 4.145 ± 0.046	4.566AspGlu: 4.566 ± 0.039	2.11AspPhe: 2.11 ± 0.018	3.279AspGly: 3.279 ± 0.028	1.202AspHis: 1.202 ± 0.014	3.734AspIle: 3.734 ± 0.027	3.531AspLys: 3.531 ± 0.032	5.034AspLeu: 5.034 ± 0.03	1.25AspMet: 1.25 ± 0.014	2.859AspAsn: 2.859 ± 0.026	2.494AspPro: 2.494 ± 0.021	1.734AspGln: 1.734 ± 0.018	3.02AspArg: 3.02 ± 0.033	4.241AspSer: 4.241 ± 0.031	3.033AspThr: 3.033 ± 0.023	3.752AspVal: 3.752 ± 0.024	0.677AspTrp: 0.677 ± 0.01	1.844AspTyr: 1.844 ± 0.019	0.0AspXaa: 0.0 ± 0.0
Glu	4.613GluAla: 4.613 ± 0.033	1.142GluCys: 1.142 ± 0.019	4.572GluAsp: 4.572 ± 0.035	7.43GluGlu: 7.43 ± 0.08	2.144GluPhe: 2.144 ± 0.016	3.3GluGly: 3.3 ± 0.03	1.506GluHis: 1.506 ± 0.016	4.479GluIle: 4.479 ± 0.031	5.616GluLys: 5.616 ± 0.046	6.101GluLeu: 6.101 ± 0.035	1.751GluMet: 1.751 ± 0.019	4.017GluAsn: 4.017 ± 0.029	2.42GluPro: 2.42 ± 0.022	2.869GluGln: 2.869 ± 0.023	4.51GluArg: 4.51 ± 0.04	4.708GluSer: 4.708 ± 0.034	4.02GluThr: 4.02 ± 0.03	3.925GluVal: 3.925 ± 0.026	0.776GluTrp: 0.776 ± 0.011	1.962GluTyr: 1.962 ± 0.018	0.0GluXaa: 0.0 ± 0.0
Phe	2.189PheAla: 2.189 ± 0.019	0.706PheCys: 0.706 ± 0.009	2.02PheAsp: 2.02 ± 0.017	2.134PheGlu: 2.134 ± 0.019	1.255PhePhe: 1.255 ± 0.017	2.187PheGly: 2.187 ± 0.023	0.87PheHis: 0.87 ± 0.012	1.828PheIle: 1.828 ± 0.018	2.022PheLys: 2.022 ± 0.019	3.264PheLeu: 3.264 ± 0.025	0.75PheMet: 0.75 ± 0.01	1.658PheAsn: 1.658 ± 0.017	1.506PhePro: 1.506 ± 0.015	1.303PheGln: 1.303 ± 0.013	1.893PheArg: 1.893 ± 0.017	2.529PheSer: 2.529 ± 0.019	1.924PheThr: 1.924 ± 0.018	2.226PheVal: 2.226 ± 0.019	0.419PheTrp: 0.419 ± 0.009	1.085PheTyr: 1.085 ± 0.013	0.0PheXaa: 0.0 ± 0.0
Gly	3.57GlyAla: 3.57 ± 0.037	0.954GlyCys: 0.954 ± 0.014	3.021GlyAsp: 3.021 ± 0.027	3.479GlyGlu: 3.479 ± 0.03	2.003GlyPhe: 2.003 ± 0.022	4.754GlyGly: 4.754 ± 0.082	1.536GlyHis: 1.536 ± 0.018	3.33GlyIle: 3.33 ± 0.025	3.771GlyLys: 3.771 ± 0.026	4.539GlyLeu: 4.539 ± 0.039	1.264GlyMet: 1.264 ± 0.015	2.663GlyAsn: 2.663 ± 0.024	2.446GlyPro: 2.446 ± 0.032	2.031GlyGln: 2.031 ± 0.027	3.551GlyArg: 3.551 ± 0.031	4.338GlySer: 4.338 ± 0.039	3.191GlyThr: 3.191 ± 0.026	3.274GlyVal: 3.274 ± 0.032	0.682GlyTrp: 0.682 ± 0.012	1.896GlyTyr: 1.896 ± 0.024	0.0GlyXaa: 0.0 ± 0.0
His	1.405HisAla: 1.405 ± 0.017	0.506HisCys: 0.506 ± 0.008	1.119HisAsp: 1.119 ± 0.012	1.393HisGlu: 1.393 ± 0.016	0.975HisPhe: 0.975 ± 0.011	1.42HisGly: 1.42 ± 0.019	1.087HisHis: 1.087 ± 0.025	1.397HisIle: 1.397 ± 0.015	1.297HisLys: 1.297 ± 0.015	2.306HisLeu: 2.306 ± 0.022	0.601HisMet: 0.601 ± 0.011	1.045HisAsn: 1.045 ± 0.014	1.358HisPro: 1.358 ± 0.017	1.098HisGln: 1.098 ± 0.015	1.505HisArg: 1.505 ± 0.016	1.714HisSer: 1.714 ± 0.018	1.272HisThr: 1.272 ± 0.016	1.537HisVal: 1.537 ± 0.015	0.29HisTrp: 0.29 ± 0.007	0.784HisTyr: 0.784 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	3.992IleAla: 3.992 ± 0.026	1.122IleCys: 1.122 ± 0.014	3.491IleAsp: 3.491 ± 0.029	4.12IleGlu: 4.12 ± 0.027	2.041IlePhe: 2.041 ± 0.02	3.142IleGly: 3.142 ± 0.026	1.291IleHis: 1.291 ± 0.014	3.344IleIle: 3.344 ± 0.029	3.819IleLys: 3.819 ± 0.028	5.329IleLeu: 5.329 ± 0.037	1.278IleMet: 1.278 ± 0.014	2.824IleAsn: 2.824 ± 0.025	2.89IlePro: 2.89 ± 0.025	2.271IleGln: 2.271 ± 0.018	3.243IleArg: 3.243 ± 0.022	4.346IleSer: 4.346 ± 0.027	3.308IleThr: 3.308 ± 0.025	3.681IleVal: 3.681 ± 0.024	0.585IleTrp: 0.585 ± 0.01	1.668IleTyr: 1.668 ± 0.018	0.0IleXaa: 0.0 ± 0.0
Lys	3.888LysAla: 3.888 ± 0.031	1.148LysCys: 1.148 ± 0.016	3.808LysAsp: 3.808 ± 0.032	5.427LysGlu: 5.427 ± 0.047	2.056LysPhe: 2.056 ± 0.018	3.013LysGly: 3.013 ± 0.027	1.52LysHis: 1.52 ± 0.017	4.196LysIle: 4.196 ± 0.027	5.697LysLys: 5.697 ± 0.052	5.861LysLeu: 5.861 ± 0.031	1.604LysMet: 1.604 ± 0.017	3.354LysAsn: 3.354 ± 0.026	2.8LysPro: 2.8 ± 0.023	2.744LysGln: 2.744 ± 0.027	4.331LysArg: 4.331 ± 0.033	4.606LysSer: 4.606 ± 0.042	3.743LysThr: 3.743 ± 0.028	3.597LysVal: 3.597 ± 0.027	0.773LysTrp: 0.773 ± 0.011	2.036LysTyr: 2.036 ± 0.02	0.0LysXaa: 0.0 ± 0.0
Leu	6.179LeuAla: 6.179 ± 0.04	1.595LeuCys: 1.595 ± 0.019	5.033LeuAsp: 5.033 ± 0.033	6.402LeuGlu: 6.402 ± 0.046	2.823LeuPhe: 2.823 ± 0.027	4.618LeuGly: 4.618 ± 0.035	2.35LeuHis: 2.35 ± 0.023	4.54LeuIle: 4.54 ± 0.035	6.136LeuLys: 6.136 ± 0.037	8.411LeuLeu: 8.411 ± 0.059	2.008LeuMet: 2.008 ± 0.021	4.128LeuAsn: 4.128 ± 0.026	4.796LeuPro: 4.796 ± 0.033	4.349LeuGln: 4.349 ± 0.032	5.881LeuArg: 5.881 ± 0.036	6.819LeuSer: 6.819 ± 0.041	5.077LeuThr: 5.077 ± 0.029	4.82LeuVal: 4.82 ± 0.033	1.004LeuTrp: 1.004 ± 0.013	2.492LeuTyr: 2.492 ± 0.024	0.0LeuXaa: 0.0 ± 0.0
Met	1.654MetAla: 1.654 ± 0.019	0.381MetCys: 0.381 ± 0.008	1.381MetAsp: 1.381 ± 0.015	1.851MetGlu: 1.851 ± 0.018	0.741MetPhe: 0.741 ± 0.011	1.147MetGly: 1.147 ± 0.014	0.521MetHis: 0.521 ± 0.008	1.239MetIle: 1.239 ± 0.015	1.585MetLys: 1.585 ± 0.017	1.994MetLeu: 1.994 ± 0.019	0.642MetMet: 0.642 ± 0.011	1.035MetAsn: 1.035 ± 0.013	1.116MetPro: 1.116 ± 0.014	1.039MetGln: 1.039 ± 0.015	1.398MetArg: 1.398 ± 0.016	1.72MetSer: 1.72 ± 0.018	1.29MetThr: 1.29 ± 0.014	1.245MetVal: 1.245 ± 0.014	0.255MetTrp: 0.255 ± 0.006	0.655MetTyr: 0.655 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.185AsnAla: 3.185 ± 0.025	0.868AsnCys: 0.868 ± 0.014	2.744AsnAsp: 2.744 ± 0.027	3.311AsnGlu: 3.311 ± 0.027	1.749AsnPhe: 1.749 ± 0.019	2.86AsnGly: 2.86 ± 0.025	1.087AsnHis: 1.087 ± 0.012	3.19AsnIle: 3.19 ± 0.025	3.098AsnLys: 3.098 ± 0.025	4.388AsnLeu: 4.388 ± 0.029	1.131AsnMet: 1.131 ± 0.015	2.957AsnAsn: 2.957 ± 0.027	2.217AsnPro: 2.217 ± 0.022	1.769AsnGln: 1.769 ± 0.02	2.566AsnArg: 2.566 ± 0.021	3.581AsnSer: 3.581 ± 0.034	2.644AsnThr: 2.644 ± 0.023	3.318AsnVal: 3.318 ± 0.024	0.502AsnTrp: 0.502 ± 0.009	1.538AsnTyr: 1.538 ± 0.017	0.0AsnXaa: 0.0 ± 0.0
Pro	3.295ProAla: 3.295 ± 0.031	0.704ProCys: 0.704 ± 0.015	2.65ProAsp: 2.65 ± 0.021	3.339ProGlu: 3.339 ± 0.03	1.53ProPhe: 1.53 ± 0.017	2.854ProGly: 2.854 ± 0.043	1.179ProHis: 1.179 ± 0.017	2.656ProIle: 2.656 ± 0.023	2.747ProLys: 2.747 ± 0.023	4.056ProLeu: 4.056 ± 0.031	0.993ProMet: 0.993 ± 0.015	2.09ProAsn: 2.09 ± 0.022	3.928ProPro: 3.928 ± 0.054	2.069ProGln: 2.069 ± 0.024	2.717ProArg: 2.717 ± 0.027	4.064ProSer: 4.064 ± 0.035	3.004ProThr: 3.004 ± 0.027	3.177ProVal: 3.177 ± 0.029	0.492ProTrp: 0.492 ± 0.009	1.442ProTyr: 1.442 ± 0.017	0.0ProXaa: 0.0 ± 0.0
Gln	2.608GlnAla: 2.608 ± 0.023	0.707GlnCys: 0.707 ± 0.013	1.995GlnAsp: 1.995 ± 0.018	3.019GlnGlu: 3.019 ± 0.025	1.296GlnPhe: 1.296 ± 0.017	1.91GlnGly: 1.91 ± 0.021	1.187GlnHis: 1.187 ± 0.018	2.279GlnIle: 2.279 ± 0.02	2.612GlnLys: 2.612 ± 0.023	3.841GlnLeu: 3.841 ± 0.03	0.998GlnMet: 0.998 ± 0.014	2.061GlnAsn: 2.061 ± 0.02	1.996GlnPro: 1.996 ± 0.024	3.558GlnGln: 3.558 ± 0.08	2.745GlnArg: 2.745 ± 0.024	2.894GlnSer: 2.894 ± 0.032	2.228GlnThr: 2.228 ± 0.021	2.193GlnVal: 2.193 ± 0.022	0.466GlnTrp: 0.466 ± 0.008	1.215GlnTyr: 1.215 ± 0.014	0.0GlnXaa: 0.0 ± 0.0
Arg	3.588ArgAla: 3.588 ± 0.029	1.089ArgCys: 1.089 ± 0.017	3.308ArgAsp: 3.308 ± 0.029	4.257ArgGlu: 4.257 ± 0.037	2.065ArgPhe: 2.065 ± 0.02	3.307ArgGly: 3.307 ± 0.032	1.567ArgHis: 1.567 ± 0.016	3.482ArgIle: 3.482 ± 0.023	4.443ArgLys: 4.443 ± 0.032	5.502ArgLeu: 5.502 ± 0.037	1.357ArgMet: 1.357 ± 0.014	2.91ArgAsn: 2.91 ± 0.025	2.719ArgPro: 2.719 ± 0.027	2.527ArgGln: 2.527 ± 0.02	4.881ArgArg: 4.881 ± 0.042	4.3ArgSer: 4.3 ± 0.035	3.183ArgThr: 3.183 ± 0.024	3.381ArgVal: 3.381 ± 0.027	0.846ArgTrp: 0.846 ± 0.014	1.817ArgTyr: 1.817 ± 0.018	0.0ArgXaa: 0.0 ± 0.0
Ser	4.808SerAla: 4.808 ± 0.03	1.252SerCys: 1.252 ± 0.016	4.476SerAsp: 4.476 ± 0.034	4.875SerGlu: 4.875 ± 0.031	2.442SerPhe: 2.442 ± 0.021	4.619SerGly: 4.619 ± 0.039	1.667SerHis: 1.667 ± 0.014	4.019SerIle: 4.019 ± 0.031	4.571SerLys: 4.571 ± 0.035	6.526SerLeu: 6.526 ± 0.038	1.641SerMet: 1.641 ± 0.017	3.764SerAsn: 3.764 ± 0.034	4.11SerPro: 4.11 ± 0.04	2.981SerGln: 2.981 ± 0.027	4.355SerArg: 4.355 ± 0.032	7.835SerSer: 7.835 ± 0.078	5.055SerThr: 5.055 ± 0.041	4.481SerVal: 4.481 ± 0.028	0.794SerTrp: 0.794 ± 0.011	2.024SerTyr: 2.024 ± 0.019	0.0SerXaa: 0.0 ± 0.0
Thr	4.145ThrAla: 4.145 ± 0.031	1.059ThrCys: 1.059 ± 0.018	3.133ThrAsp: 3.133 ± 0.023	3.865ThrGlu: 3.865 ± 0.031	1.981ThrPhe: 1.981 ± 0.018	3.353ThrGly: 3.353 ± 0.028	1.181ThrHis: 1.181 ± 0.014	3.383ThrIle: 3.383 ± 0.026	3.535ThrLys: 3.535 ± 0.026	5.212ThrLeu: 5.212 ± 0.034	1.324ThrMet: 1.324 ± 0.015	2.646ThrAsn: 2.646 ± 0.025	3.255ThrPro: 3.255 ± 0.028	2.106ThrGln: 2.106 ± 0.018	3.01ThrArg: 3.01 ± 0.024	4.953ThrSer: 4.953 ± 0.043	4.269ThrThr: 4.269 ± 0.051	3.792ThrVal: 3.792 ± 0.028	0.649ThrTrp: 0.649 ± 0.009	1.605ThrTyr: 1.605 ± 0.014	0.0ThrXaa: 0.0 ± 0.0
Val	4.416ValAla: 4.416 ± 0.029	1.144ValCys: 1.144 ± 0.016	3.413ValAsp: 3.413 ± 0.025	4.17ValGlu: 4.17 ± 0.026	2.032ValPhe: 2.032 ± 0.019	3.125ValGly: 3.125 ± 0.027	1.416ValHis: 1.416 ± 0.015	3.508ValIle: 3.508 ± 0.026	3.839ValLys: 3.839 ± 0.025	5.375ValLeu: 5.375 ± 0.036	1.375ValMet: 1.375 ± 0.014	2.788ValAsn: 2.788 ± 0.022	3.167ValPro: 3.167 ± 0.03	2.425ValGln: 2.425 ± 0.022	3.324ValArg: 3.324 ± 0.024	4.49ValSer: 4.49 ± 0.03	3.832ValThr: 3.832 ± 0.023	3.905ValVal: 3.905 ± 0.035	0.706ValTrp: 0.706 ± 0.01	1.698ValTyr: 1.698 ± 0.015	0.0ValXaa: 0.0 ± 0.0
Trp	0.663TrpAla: 0.663 ± 0.012	0.209TrpCys: 0.209 ± 0.006	0.644TrpAsp: 0.644 ± 0.011	0.722TrpGlu: 0.722 ± 0.013	0.398TrpPhe: 0.398 ± 0.008	0.598TrpGly: 0.598 ± 0.011	0.291TrpHis: 0.291 ± 0.007	0.706TrpIle: 0.706 ± 0.012	0.854TrpLys: 0.854 ± 0.012	1.106TrpLeu: 1.106 ± 0.015	0.282TrpMet: 0.282 ± 0.006	0.6TrpAsn: 0.6 ± 0.01	0.463TrpPro: 0.463 ± 0.009	0.516TrpGln: 0.516 ± 0.009	0.813TrpArg: 0.813 ± 0.012	0.811TrpSer: 0.811 ± 0.011	0.67TrpThr: 0.67 ± 0.011	0.566TrpVal: 0.566 ± 0.01	0.197TrpTrp: 0.197 ± 0.006	0.32TrpTyr: 0.32 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.87TyrAla: 1.87 ± 0.017	0.595TyrCys: 0.595 ± 0.009	1.656TyrAsp: 1.656 ± 0.018	1.889TyrGlu: 1.889 ± 0.017	1.164TyrPhe: 1.164 ± 0.014	1.824TyrGly: 1.824 ± 0.018	0.788TyrHis: 0.788 ± 0.011	1.657TyrIle: 1.657 ± 0.018	1.817TyrLys: 1.817 ± 0.018	2.826TyrLeu: 2.826 ± 0.025	0.683TyrMet: 0.683 ± 0.01	1.503TyrAsn: 1.503 ± 0.018	1.353TyrPro: 1.353 ± 0.02	1.152TyrGln: 1.152 ± 0.014	1.801TyrArg: 1.801 ± 0.019	1.985TyrSer: 1.985 ± 0.02	1.573TyrThr: 1.573 ± 0.017	1.852TyrVal: 1.852 ± 0.018	0.369TyrTrp: 0.369 ± 0.008	1.065TyrTyr: 1.065 ± 0.02	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 18044 proteins (6832129 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---