Amino acid dipepetide frequency for Trueperella bernardiae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	15.721AlaAla: 15.721 ± 0.275	0.835AlaCys: 0.835 ± 0.045	7.79AlaAsp: 7.79 ± 0.132	8.124AlaGlu: 8.124 ± 0.155	3.591AlaPhe: 3.591 ± 0.081	11.913AlaGly: 11.913 ± 0.199	2.415AlaHis: 2.415 ± 0.061	6.233AlaIle: 6.233 ± 0.115	4.039AlaLys: 4.039 ± 0.098	12.232AlaLeu: 12.232 ± 0.187	3.018AlaMet: 3.018 ± 0.079	3.041AlaAsn: 3.041 ± 0.076	5.279AlaPro: 5.279 ± 0.105	4.126AlaGln: 4.126 ± 0.087	8.277AlaArg: 8.277 ± 0.138	6.279AlaSer: 6.279 ± 0.097	6.956AlaThr: 6.956 ± 0.142	9.323AlaVal: 9.323 ± 0.145	1.675AlaTrp: 1.675 ± 0.058	2.542AlaTyr: 2.542 ± 0.068	0.0AlaXaa: 0.0 ± 0.0
Cys	0.748CysAla: 0.748 ± 0.033	0.069CysCys: 0.069 ± 0.013	0.356CysAsp: 0.356 ± 0.026	0.394CysGlu: 0.394 ± 0.025	0.186CysPhe: 0.186 ± 0.018	0.73CysGly: 0.73 ± 0.036	0.18CysHis: 0.18 ± 0.022	0.232CysIle: 0.232 ± 0.02	0.166CysLys: 0.166 ± 0.017	0.58CysLeu: 0.58 ± 0.031	0.104CysMet: 0.104 ± 0.013	0.152CysAsn: 0.152 ± 0.015	0.379CysPro: 0.379 ± 0.024	0.196CysGln: 0.196 ± 0.016	0.372CysArg: 0.372 ± 0.029	0.404CysSer: 0.404 ± 0.029	0.387CysThr: 0.387 ± 0.027	0.435CysVal: 0.435 ± 0.029	0.072CysTrp: 0.072 ± 0.012	0.156CysTyr: 0.156 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	7.594AspAla: 7.594 ± 0.128	0.315AspCys: 0.315 ± 0.025	3.728AspAsp: 3.728 ± 0.104	4.088AspGlu: 4.088 ± 0.09	2.001AspPhe: 2.001 ± 0.062	5.258AspGly: 5.258 ± 0.121	1.193AspHis: 1.193 ± 0.046	2.896AspIle: 2.896 ± 0.079	1.555AspLys: 1.555 ± 0.061	5.863AspLeu: 5.863 ± 0.108	1.306AspMet: 1.306 ± 0.054	1.331AspAsn: 1.331 ± 0.05	3.657AspPro: 3.657 ± 0.087	1.794AspGln: 1.794 ± 0.061	3.599AspArg: 3.599 ± 0.091	3.242AspSer: 3.242 ± 0.082	2.945AspThr: 2.945 ± 0.079	5.538AspVal: 5.538 ± 0.104	0.794AspTrp: 0.794 ± 0.037	1.72AspTyr: 1.72 ± 0.057	0.0AspXaa: 0.0 ± 0.0
Glu	7.997GluAla: 7.997 ± 0.165	0.356GluCys: 0.356 ± 0.026	3.538GluAsp: 3.538 ± 0.082	4.513GluGlu: 4.513 ± 0.107	1.929GluPhe: 1.929 ± 0.058	4.942GluGly: 4.942 ± 0.098	1.425GluHis: 1.425 ± 0.057	3.316GluIle: 3.316 ± 0.092	2.097GluLys: 2.097 ± 0.071	7.236GluLeu: 7.236 ± 0.135	1.41GluMet: 1.41 ± 0.056	1.599GluAsn: 1.599 ± 0.048	3.299GluPro: 3.299 ± 0.089	2.336GluGln: 2.336 ± 0.067	5.12GluArg: 5.12 ± 0.121	3.136GluSer: 3.136 ± 0.068	2.843GluThr: 2.843 ± 0.064	5.411GluVal: 5.411 ± 0.102	0.888GluTrp: 0.888 ± 0.044	1.324GluTyr: 1.324 ± 0.051	0.0GluXaa: 0.0 ± 0.0
Phe	3.967PheAla: 3.967 ± 0.079	0.214PheCys: 0.214 ± 0.02	2.267PheAsp: 2.267 ± 0.064	1.901PheGlu: 1.901 ± 0.065	1.226PhePhe: 1.226 ± 0.043	3.235PheGly: 3.235 ± 0.083	0.634PheHis: 0.634 ± 0.031	1.552PheIle: 1.552 ± 0.055	0.768PheLys: 0.768 ± 0.038	2.764PheLeu: 2.764 ± 0.084	0.68PheMet: 0.68 ± 0.036	0.873PheAsn: 0.873 ± 0.044	1.474PhePro: 1.474 ± 0.051	0.769PheGln: 0.769 ± 0.038	1.593PheArg: 1.593 ± 0.05	2.064PheSer: 2.064 ± 0.057	2.112PheThr: 2.112 ± 0.065	2.738PheVal: 2.738 ± 0.072	0.461PheTrp: 0.461 ± 0.029	0.82PheTyr: 0.82 ± 0.047	0.0PheXaa: 0.0 ± 0.0
Gly	9.836GlyAla: 9.836 ± 0.183	0.623GlyCys: 0.623 ± 0.034	4.7GlyAsp: 4.7 ± 0.107	5.79GlyGlu: 5.79 ± 0.104	2.975GlyPhe: 2.975 ± 0.078	7.014GlyGly: 7.014 ± 0.132	1.855GlyHis: 1.855 ± 0.057	4.538GlyIle: 4.538 ± 0.092	3.471GlyLys: 3.471 ± 0.093	8.042GlyLeu: 8.042 ± 0.123	2.351GlyMet: 2.351 ± 0.07	2.245GlyAsn: 2.245 ± 0.076	3.449GlyPro: 3.449 ± 0.084	3.044GlyGln: 3.044 ± 0.076	5.655GlyArg: 5.655 ± 0.118	4.859GlySer: 4.859 ± 0.093	5.209GlyThr: 5.209 ± 0.122	7.523GlyVal: 7.523 ± 0.111	1.451GlyTrp: 1.451 ± 0.059	2.468GlyTyr: 2.468 ± 0.061	0.0GlyXaa: 0.0 ± 0.0
His	2.244HisAla: 2.244 ± 0.076	0.137HisCys: 0.137 ± 0.015	1.354HisAsp: 1.354 ± 0.053	1.194HisGlu: 1.194 ± 0.042	0.611HisPhe: 0.611 ± 0.033	1.865HisGly: 1.865 ± 0.06	0.507HisHis: 0.507 ± 0.032	0.972HisIle: 0.972 ± 0.037	0.529HisLys: 0.529 ± 0.03	2.001HisLeu: 2.001 ± 0.061	0.466HisMet: 0.466 ± 0.027	0.489HisAsn: 0.489 ± 0.029	1.316HisPro: 1.316 ± 0.051	0.547HisGln: 0.547 ± 0.03	1.333HisArg: 1.333 ± 0.052	0.955HisSer: 0.955 ± 0.045	1.117HisThr: 1.117 ± 0.037	1.677HisVal: 1.677 ± 0.053	0.264HisTrp: 0.264 ± 0.02	0.499HisTyr: 0.499 ± 0.028	0.0HisXaa: 0.0 ± 0.0
Ile	6.488IleAla: 6.488 ± 0.116	0.374IleCys: 0.374 ± 0.027	3.69IleAsp: 3.69 ± 0.077	3.316IleGlu: 3.316 ± 0.08	1.632IlePhe: 1.632 ± 0.066	4.53IleGly: 4.53 ± 0.117	0.955IleHis: 0.955 ± 0.038	2.435IleIle: 2.435 ± 0.072	1.339IleLys: 1.339 ± 0.057	4.392IleLeu: 4.392 ± 0.095	1.071IleMet: 1.071 ± 0.047	1.418IleAsn: 1.418 ± 0.051	2.616IlePro: 2.616 ± 0.073	1.244IleGln: 1.244 ± 0.04	2.822IleArg: 2.822 ± 0.064	3.019IleSer: 3.019 ± 0.081	2.973IleThr: 2.973 ± 0.072	4.607IleVal: 4.607 ± 0.093	0.562IleTrp: 0.562 ± 0.032	1.143IleTyr: 1.143 ± 0.04	0.0IleXaa: 0.0 ± 0.0
Lys	3.548LysAla: 3.548 ± 0.102	0.135LysCys: 0.135 ± 0.017	1.873LysAsp: 1.873 ± 0.067	1.866LysGlu: 1.866 ± 0.062	0.797LysPhe: 0.797 ± 0.033	2.123LysGly: 2.123 ± 0.062	0.588LysHis: 0.588 ± 0.03	1.764LysIle: 1.764 ± 0.06	1.431LysLys: 1.431 ± 0.062	2.868LysLeu: 2.868 ± 0.075	0.921LysMet: 0.921 ± 0.043	1.023LysAsn: 1.023 ± 0.039	1.664LysPro: 1.664 ± 0.058	0.876LysGln: 0.876 ± 0.048	2.059LysArg: 2.059 ± 0.059	1.492LysSer: 1.492 ± 0.053	1.759LysThr: 1.759 ± 0.058	2.729LysVal: 2.729 ± 0.08	0.3LysTrp: 0.3 ± 0.022	0.769LysTyr: 0.769 ± 0.04	0.0LysXaa: 0.0 ± 0.0
Leu	13.262LeuAla: 13.262 ± 0.195	0.55LeuCys: 0.55 ± 0.029	6.133LeuAsp: 6.133 ± 0.114	5.912LeuGlu: 5.912 ± 0.117	2.739LeuPhe: 2.739 ± 0.077	8.506LeuGly: 8.506 ± 0.134	1.713LeuHis: 1.713 ± 0.058	4.802LeuIle: 4.802 ± 0.096	2.489LeuLys: 2.489 ± 0.06	8.419LeuLeu: 8.419 ± 0.161	1.998LeuMet: 1.998 ± 0.062	2.304LeuAsn: 2.304 ± 0.06	4.971LeuPro: 4.971 ± 0.088	2.209LeuGln: 2.209 ± 0.065	6.266LeuArg: 6.266 ± 0.125	5.543LeuSer: 5.543 ± 0.102	6.245LeuThr: 6.245 ± 0.11	7.836LeuVal: 7.836 ± 0.13	1.023LeuTrp: 1.023 ± 0.037	1.924LeuTyr: 1.924 ± 0.055	0.0LeuXaa: 0.0 ± 0.0
Met	2.749MetAla: 2.749 ± 0.077	0.165MetCys: 0.165 ± 0.016	1.249MetAsp: 1.249 ± 0.048	1.161MetGlu: 1.161 ± 0.048	0.728MetPhe: 0.728 ± 0.039	1.881MetGly: 1.881 ± 0.057	0.432MetHis: 0.432 ± 0.023	1.24MetIle: 1.24 ± 0.055	0.863MetLys: 0.863 ± 0.037	2.11MetLeu: 2.11 ± 0.066	0.537MetMet: 0.537 ± 0.034	0.792MetAsn: 0.792 ± 0.034	1.217MetPro: 1.217 ± 0.045	0.577MetGln: 0.577 ± 0.032	1.611MetArg: 1.611 ± 0.053	1.705MetSer: 1.705 ± 0.057	1.621MetThr: 1.621 ± 0.051	1.769MetVal: 1.769 ± 0.056	0.305MetTrp: 0.305 ± 0.023	0.461MetTyr: 0.461 ± 0.025	0.0MetXaa: 0.0 ± 0.0
Asn	2.97AsnAla: 2.97 ± 0.077	0.178AsnCys: 0.178 ± 0.017	1.512AsnAsp: 1.512 ± 0.048	1.519AsnGlu: 1.519 ± 0.056	0.84AsnPhe: 0.84 ± 0.037	2.095AsnGly: 2.095 ± 0.08	0.493AsnHis: 0.493 ± 0.03	1.229AsnIle: 1.229 ± 0.053	0.796AsnLys: 0.796 ± 0.038	2.603AsnLeu: 2.603 ± 0.062	0.609AsnMet: 0.609 ± 0.036	0.68AsnAsn: 0.68 ± 0.036	1.916AsnPro: 1.916 ± 0.065	0.832AsnGln: 0.832 ± 0.039	1.492AsnArg: 1.492 ± 0.054	1.272AsnSer: 1.272 ± 0.049	1.509AsnThr: 1.509 ± 0.052	2.211AsnVal: 2.211 ± 0.064	0.458AsnTrp: 0.458 ± 0.028	0.672AsnTyr: 0.672 ± 0.036	0.0AsnXaa: 0.0 ± 0.0
Pro	6.719ProAla: 6.719 ± 0.126	0.247ProCys: 0.247 ± 0.02	3.331ProAsp: 3.331 ± 0.08	4.177ProGlu: 4.177 ± 0.095	1.543ProPhe: 1.543 ± 0.052	4.797ProGly: 4.797 ± 0.095	1.061ProHis: 1.061 ± 0.041	2.272ProIle: 2.272 ± 0.062	1.361ProLys: 1.361 ± 0.046	3.988ProLeu: 3.988 ± 0.08	1.03ProMet: 1.03 ± 0.04	1.354ProAsn: 1.354 ± 0.045	1.583ProPro: 1.583 ± 0.061	1.543ProGln: 1.543 ± 0.055	2.731ProArg: 2.731 ± 0.08	2.744ProSer: 2.744 ± 0.087	3.056ProThr: 3.056 ± 0.079	4.079ProVal: 4.079 ± 0.092	0.759ProTrp: 0.759 ± 0.034	1.242ProTyr: 1.242 ± 0.047	0.0ProXaa: 0.0 ± 0.0
Gln	3.978GlnAla: 3.978 ± 0.093	0.188GlnCys: 0.188 ± 0.017	1.422GlnAsp: 1.422 ± 0.05	1.697GlnGlu: 1.697 ± 0.057	0.998GlnPhe: 0.998 ± 0.04	2.094GlnGly: 2.094 ± 0.057	0.55GlnHis: 0.55 ± 0.028	2.024GlnIle: 2.024 ± 0.058	0.776GlnLys: 0.776 ± 0.039	3.225GlnLeu: 3.225 ± 0.08	0.881GlnMet: 0.881 ± 0.04	0.728GlnAsn: 0.728 ± 0.034	1.539GlnPro: 1.539 ± 0.055	1.023GlnGln: 1.023 ± 0.049	2.232GlnArg: 2.232 ± 0.078	1.423GlnSer: 1.423 ± 0.049	1.547GlnThr: 1.547 ± 0.051	2.813GlnVal: 2.813 ± 0.063	0.443GlnTrp: 0.443 ± 0.03	0.7GlnTyr: 0.7 ± 0.037	0.0GlnXaa: 0.0 ± 0.0
Arg	7.768ArgAla: 7.768 ± 0.15	0.359ArgCys: 0.359 ± 0.026	3.433ArgAsp: 3.433 ± 0.076	4.81ArgGlu: 4.81 ± 0.098	2.107ArgPhe: 2.107 ± 0.059	4.945ArgGly: 4.945 ± 0.097	1.387ArgHis: 1.387 ± 0.053	3.316ArgIle: 3.316 ± 0.072	2.102ArgLys: 2.102 ± 0.069	6.077ArgLeu: 6.077 ± 0.113	1.647ArgMet: 1.647 ± 0.056	1.66ArgAsn: 1.66 ± 0.058	3.044ArgPro: 3.044 ± 0.069	2.298ArgGln: 2.298 ± 0.062	5.151ArgArg: 5.151 ± 0.125	3.453ArgSer: 3.453 ± 0.095	3.551ArgThr: 3.551 ± 0.081	5.161ArgVal: 5.161 ± 0.108	0.941ArgTrp: 0.941 ± 0.041	1.679ArgTyr: 1.679 ± 0.056	0.0ArgXaa: 0.0 ± 0.0
Ser	6.711SerAla: 6.711 ± 0.11	0.311SerCys: 0.311 ± 0.024	3.034SerAsp: 3.034 ± 0.08	3.199SerGlu: 3.199 ± 0.087	2.054SerPhe: 2.054 ± 0.061	5.395SerGly: 5.395 ± 0.108	1.196SerHis: 1.196 ± 0.039	2.748SerIle: 2.748 ± 0.077	1.529SerLys: 1.529 ± 0.059	5.164SerLeu: 5.164 ± 0.103	1.282SerMet: 1.282 ± 0.05	1.331SerAsn: 1.331 ± 0.046	2.716SerPro: 2.716 ± 0.076	1.809SerGln: 1.809 ± 0.049	3.359SerArg: 3.359 ± 0.071	3.206SerSer: 3.206 ± 0.076	3.248SerThr: 3.248 ± 0.072	4.494SerVal: 4.494 ± 0.093	0.835SerTrp: 0.835 ± 0.046	1.425SerTyr: 1.425 ± 0.047	0.0SerXaa: 0.0 ± 0.0
Thr	6.289ThrAla: 6.289 ± 0.119	0.399ThrCys: 0.399 ± 0.028	3.308ThrAsp: 3.308 ± 0.078	3.237ThrGlu: 3.237 ± 0.074	2.089ThrPhe: 2.089 ± 0.064	5.352ThrGly: 5.352 ± 0.107	1.194ThrHis: 1.194 ± 0.046	3.143ThrIle: 3.143 ± 0.074	1.728ThrLys: 1.728 ± 0.062	5.643ThrLeu: 5.643 ± 0.108	1.199ThrMet: 1.199 ± 0.054	1.611ThrAsn: 1.611 ± 0.054	3.51ThrPro: 3.51 ± 0.081	1.669ThrGln: 1.669 ± 0.057	3.346ThrArg: 3.346 ± 0.083	3.528ThrSer: 3.528 ± 0.076	3.683ThrThr: 3.683 ± 0.077	4.938ThrVal: 4.938 ± 0.119	0.881ThrTrp: 0.881 ± 0.036	1.524ThrTyr: 1.524 ± 0.054	0.0ThrXaa: 0.0 ± 0.0
Val	10.745ValAla: 10.745 ± 0.173	0.591ValCys: 0.591 ± 0.03	5.388ValAsp: 5.388 ± 0.104	5.49ValGlu: 5.49 ± 0.121	2.665ValPhe: 2.665 ± 0.067	7.236ValGly: 7.236 ± 0.13	1.499ValHis: 1.499 ± 0.049	4.35ValIle: 4.35 ± 0.102	2.416ValLys: 2.416 ± 0.064	7.768ValLeu: 7.768 ± 0.121	1.812ValMet: 1.812 ± 0.056	2.099ValAsn: 2.099 ± 0.062	4.2ValPro: 4.2 ± 0.075	2.066ValGln: 2.066 ± 0.061	5.354ValArg: 5.354 ± 0.103	4.66ValSer: 4.66 ± 0.092	5.362ValThr: 5.362 ± 0.109	8.683ValVal: 8.683 ± 0.163	1.015ValTrp: 1.015 ± 0.04	1.731ValTyr: 1.731 ± 0.057	0.0ValXaa: 0.0 ± 0.0
Trp	1.438TrpAla: 1.438 ± 0.056	0.084TrpCys: 0.084 ± 0.012	0.822TrpAsp: 0.822 ± 0.037	0.82TrpGlu: 0.82 ± 0.035	0.506TrpPhe: 0.506 ± 0.035	1.003TrpGly: 1.003 ± 0.044	0.32TrpHis: 0.32 ± 0.023	0.667TrpIle: 0.667 ± 0.036	0.455TrpLys: 0.455 ± 0.03	1.479TrpLeu: 1.479 ± 0.06	0.389TrpMet: 0.389 ± 0.029	0.478TrpAsn: 0.478 ± 0.028	0.611TrpPro: 0.611 ± 0.034	0.562TrpGln: 0.562 ± 0.034	0.921TrpArg: 0.921 ± 0.038	0.753TrpSer: 0.753 ± 0.04	0.766TrpThr: 0.766 ± 0.037	1.092TrpVal: 1.092 ± 0.045	0.29TrpTrp: 0.29 ± 0.024	0.315TrpTyr: 0.315 ± 0.026	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.639TyrAla: 2.639 ± 0.056	0.168TyrCys: 0.168 ± 0.016	1.491TyrAsp: 1.491 ± 0.044	1.507TyrGlu: 1.507 ± 0.049	0.893TyrPhe: 0.893 ± 0.04	2.183TyrGly: 2.183 ± 0.07	0.481TyrHis: 0.481 ± 0.03	0.898TyrIle: 0.898 ± 0.04	0.679TyrLys: 0.679 ± 0.041	2.39TyrLeu: 2.39 ± 0.059	0.461TyrMet: 0.461 ± 0.03	0.677TyrAsn: 0.677 ± 0.039	1.174TyrPro: 1.174 ± 0.049	0.763TyrGln: 0.763 ± 0.04	1.596TyrArg: 1.596 ± 0.054	1.306TyrSer: 1.306 ± 0.054	1.382TyrThr: 1.382 ± 0.054	2.074TyrVal: 2.074 ± 0.06	0.353TyrTrp: 0.353 ± 0.029	0.644TyrTyr: 0.644 ± 0.033	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 1762 proteins (607078 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---