Amino acid dipepetide frequency for Gemmatimonas phototrophica

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	16.74AlaAla: 16.74 ± 0.191	0.998AlaCys: 0.998 ± 0.032	6.424AlaAsp: 6.424 ± 0.073	6.212AlaGlu: 6.212 ± 0.096	4.122AlaPhe: 4.122 ± 0.068	10.298AlaGly: 10.298 ± 0.107	2.365AlaHis: 2.365 ± 0.05	5.322AlaIle: 5.322 ± 0.079	3.087AlaLys: 3.087 ± 0.072	14.076AlaLeu: 14.076 ± 0.157	3.326AlaMet: 3.326 ± 0.054	3.262AlaAsn: 3.262 ± 0.055	6.89AlaPro: 6.89 ± 0.093	4.963AlaGln: 4.963 ± 0.07	9.81AlaArg: 9.81 ± 0.113	7.014AlaSer: 7.014 ± 0.088	7.845AlaThr: 7.845 ± 0.094	9.982AlaVal: 9.982 ± 0.105	1.728AlaTrp: 1.728 ± 0.048	2.428AlaTyr: 2.428 ± 0.05	0.0AlaXaa: 0.0 ± 0.0
Cys	0.939CysAla: 0.939 ± 0.032	0.092CysCys: 0.092 ± 0.01	0.441CysAsp: 0.441 ± 0.022	0.351CysGlu: 0.351 ± 0.018	0.25CysPhe: 0.25 ± 0.015	0.806CysGly: 0.806 ± 0.031	0.199CysHis: 0.199 ± 0.016	0.287CysIle: 0.287 ± 0.016	0.131CysLys: 0.131 ± 0.01	0.541CysLeu: 0.541 ± 0.023	0.136CysMet: 0.136 ± 0.012	0.183CysAsn: 0.183 ± 0.014	0.361CysPro: 0.361 ± 0.019	0.177CysGln: 0.177 ± 0.012	0.46CysArg: 0.46 ± 0.021	0.409CysSer: 0.409 ± 0.021	0.498CysThr: 0.498 ± 0.021	0.537CysVal: 0.537 ± 0.024	0.104CysTrp: 0.104 ± 0.012	0.148CysTyr: 0.148 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	7.584AspAla: 7.584 ± 0.105	0.295AspCys: 0.295 ± 0.016	2.953AspAsp: 2.953 ± 0.069	2.921AspGlu: 2.921 ± 0.06	1.741AspPhe: 1.741 ± 0.039	5.148AspGly: 5.148 ± 0.081	1.007AspHis: 1.007 ± 0.029	2.204AspIle: 2.204 ± 0.045	1.181AspLys: 1.181 ± 0.034	4.922AspLeu: 4.922 ± 0.066	0.991AspMet: 0.991 ± 0.028	1.103AspAsn: 1.103 ± 0.034	3.01AspPro: 3.01 ± 0.054	1.501AspGln: 1.501 ± 0.035	4.015AspArg: 4.015 ± 0.064	3.179AspSer: 3.179 ± 0.074	3.115AspThr: 3.115 ± 0.057	4.989AspVal: 4.989 ± 0.064	0.782AspTrp: 0.782 ± 0.028	1.151AspTyr: 1.151 ± 0.038	0.0AspXaa: 0.0 ± 0.0
Glu	6.243GluAla: 6.243 ± 0.094	0.338GluCys: 0.338 ± 0.018	1.96GluAsp: 1.96 ± 0.049	2.467GluGlu: 2.467 ± 0.057	1.615GluPhe: 1.615 ± 0.033	3.715GluGly: 3.715 ± 0.059	1.206GluHis: 1.206 ± 0.031	2.246GluIle: 2.246 ± 0.052	1.441GluLys: 1.441 ± 0.047	5.419GluLeu: 5.419 ± 0.087	1.192GluMet: 1.192 ± 0.038	1.13GluAsn: 1.13 ± 0.032	2.36GluPro: 2.36 ± 0.048	2.499GluGln: 2.499 ± 0.055	5.195GluArg: 5.195 ± 0.085	2.564GluSer: 2.564 ± 0.05	2.588GluThr: 2.588 ± 0.058	3.917GluVal: 3.917 ± 0.065	0.836GluTrp: 0.836 ± 0.03	1.064GluTyr: 1.064 ± 0.029	0.0GluXaa: 0.0 ± 0.0
Phe	4.23PheAla: 4.23 ± 0.067	0.241PheCys: 0.241 ± 0.015	2.311PheAsp: 2.311 ± 0.047	1.724PheGlu: 1.724 ± 0.037	1.197PhePhe: 1.197 ± 0.033	3.302PheGly: 3.302 ± 0.07	0.597PheHis: 0.597 ± 0.023	1.197PheIle: 1.197 ± 0.034	0.807PheLys: 0.807 ± 0.026	2.85PheLeu: 2.85 ± 0.06	0.669PheMet: 0.669 ± 0.026	0.988PheAsn: 0.988 ± 0.038	1.514PhePro: 1.514 ± 0.034	0.887PheGln: 0.887 ± 0.027	2.274PheArg: 2.274 ± 0.042	2.108PheSer: 2.108 ± 0.045	2.401PheThr: 2.401 ± 0.047	2.936PheVal: 2.936 ± 0.052	0.415PheTrp: 0.415 ± 0.017	0.804PheTyr: 0.804 ± 0.026	0.0PheXaa: 0.0 ± 0.0
Gly	10.553GlyAla: 10.553 ± 0.12	0.7GlyCys: 0.7 ± 0.024	4.612GlyAsp: 4.612 ± 0.071	4.186GlyGlu: 4.186 ± 0.069	3.102GlyPhe: 3.102 ± 0.063	7.843GlyGly: 7.843 ± 0.12	1.678GlyHis: 1.678 ± 0.044	3.956GlyIle: 3.956 ± 0.061	2.61GlyLys: 2.61 ± 0.056	7.656GlyLeu: 7.656 ± 0.077	2.274GlyMet: 2.274 ± 0.045	2.39GlyAsn: 2.39 ± 0.055	3.347GlyPro: 3.347 ± 0.05	2.796GlyGln: 2.796 ± 0.051	6.126GlyArg: 6.126 ± 0.078	4.844GlySer: 4.844 ± 0.076	6.044GlyThr: 6.044 ± 0.085	7.472GlyVal: 7.472 ± 0.091	1.437GlyTrp: 1.437 ± 0.039	2.196GlyTyr: 2.196 ± 0.045	0.0GlyXaa: 0.0 ± 0.0
His	2.539HisAla: 2.539 ± 0.058	0.182HisCys: 0.182 ± 0.013	1.298HisAsp: 1.298 ± 0.038	1.155HisGlu: 1.155 ± 0.034	0.702HisPhe: 0.702 ± 0.024	1.951HisGly: 1.951 ± 0.041	0.56HisHis: 0.56 ± 0.023	0.755HisIle: 0.755 ± 0.029	0.358HisLys: 0.358 ± 0.017	1.946HisLeu: 1.946 ± 0.049	0.365HisMet: 0.365 ± 0.016	0.454HisAsn: 0.454 ± 0.017	1.332HisPro: 1.332 ± 0.035	0.567HisGln: 0.567 ± 0.023	1.417HisArg: 1.417 ± 0.037	0.866HisSer: 0.866 ± 0.033	1.135HisThr: 1.135 ± 0.03	1.662HisVal: 1.662 ± 0.044	0.333HisTrp: 0.333 ± 0.017	0.465HisTyr: 0.465 ± 0.019	0.0HisXaa: 0.0 ± 0.0
Ile	5.769IleAla: 5.769 ± 0.084	0.287IleCys: 0.287 ± 0.016	2.598IleAsp: 2.598 ± 0.053	2.31IleGlu: 2.31 ± 0.051	1.085IlePhe: 1.085 ± 0.029	4.033IleGly: 4.033 ± 0.06	0.683IleHis: 0.683 ± 0.025	1.55IleIle: 1.55 ± 0.046	1.04IleLys: 1.04 ± 0.033	3.035IleLeu: 3.035 ± 0.063	0.812IleMet: 0.812 ± 0.03	1.155IleAsn: 1.155 ± 0.032	2.375IlePro: 2.375 ± 0.052	1.042IleGln: 1.042 ± 0.031	2.787IleArg: 2.787 ± 0.048	2.234IleSer: 2.234 ± 0.046	3.021IleThr: 3.021 ± 0.059	3.768IleVal: 3.768 ± 0.057	0.416IleTrp: 0.416 ± 0.018	0.786IleTyr: 0.786 ± 0.029	0.0IleXaa: 0.0 ± 0.0
Lys	3.14LysAla: 3.14 ± 0.073	0.137LysCys: 0.137 ± 0.011	1.259LysAsp: 1.259 ± 0.044	1.206LysGlu: 1.206 ± 0.042	0.685LysPhe: 0.685 ± 0.029	2.062LysGly: 2.062 ± 0.045	0.459LysHis: 0.459 ± 0.02	0.971LysIle: 0.971 ± 0.038	1.002LysLys: 1.002 ± 0.051	2.303LysLeu: 2.303 ± 0.05	0.604LysMet: 0.604 ± 0.023	0.717LysAsn: 0.717 ± 0.026	1.473LysPro: 1.473 ± 0.041	0.957LysGln: 0.957 ± 0.033	1.877LysArg: 1.877 ± 0.046	1.328LysSer: 1.328 ± 0.039	1.412LysThr: 1.412 ± 0.036	1.981LysVal: 1.981 ± 0.046	0.322LysTrp: 0.322 ± 0.015	0.6LysTyr: 0.6 ± 0.028	0.0LysXaa: 0.0 ± 0.0
Leu	13.055LeuAla: 13.055 ± 0.14	0.711LeuCys: 0.711 ± 0.026	5.783LeuAsp: 5.783 ± 0.072	5.225LeuGlu: 5.225 ± 0.081	3.273LeuPhe: 3.273 ± 0.057	8.23LeuGly: 8.23 ± 0.079	1.993LeuHis: 1.993 ± 0.045	3.335LeuIle: 3.335 ± 0.057	2.326LeuLys: 2.326 ± 0.058	10.523LeuLeu: 10.523 ± 0.142	1.986LeuMet: 1.986 ± 0.046	2.324LeuAsn: 2.324 ± 0.051	5.846LeuPro: 5.846 ± 0.082	3.441LeuGln: 3.441 ± 0.065	8.129LeuArg: 8.129 ± 0.097	6.063LeuSer: 6.063 ± 0.078	6.221LeuThr: 6.221 ± 0.07	8.548LeuVal: 8.548 ± 0.109	1.314LeuTrp: 1.314 ± 0.04	2.006LeuTyr: 2.006 ± 0.045	0.0LeuXaa: 0.0 ± 0.0
Met	2.961MetAla: 2.961 ± 0.053	0.146MetCys: 0.146 ± 0.011	1.022MetAsp: 1.022 ± 0.031	0.985MetGlu: 0.985 ± 0.032	0.619MetPhe: 0.619 ± 0.021	1.794MetGly: 1.794 ± 0.038	0.493MetHis: 0.493 ± 0.023	0.88MetIle: 0.88 ± 0.028	0.584MetLys: 0.584 ± 0.022	2.444MetLeu: 2.444 ± 0.045	0.522MetMet: 0.522 ± 0.021	0.591MetAsn: 0.591 ± 0.024	1.533MetPro: 1.533 ± 0.034	0.966MetGln: 0.966 ± 0.031	1.898MetArg: 1.898 ± 0.038	1.565MetSer: 1.565 ± 0.038	1.548MetThr: 1.548 ± 0.036	1.749MetVal: 1.749 ± 0.039	0.244MetTrp: 0.244 ± 0.015	0.393MetTyr: 0.393 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	3.446AsnAla: 3.446 ± 0.052	0.193AsnCys: 0.193 ± 0.012	1.466AsnAsp: 1.466 ± 0.039	1.184AsnGlu: 1.184 ± 0.034	0.838AsnPhe: 0.838 ± 0.037	2.75AsnGly: 2.75 ± 0.061	0.422AsnHis: 0.422 ± 0.019	1.154AsnIle: 1.154 ± 0.035	0.556AsnLys: 0.556 ± 0.026	2.087AsnLeu: 2.087 ± 0.047	0.491AsnMet: 0.491 ± 0.019	0.776AsnAsn: 0.776 ± 0.034	1.837AsnPro: 1.837 ± 0.05	0.663AsnGln: 0.663 ± 0.026	1.653AsnArg: 1.653 ± 0.04	1.292AsnSer: 1.292 ± 0.039	1.607AsnThr: 1.607 ± 0.047	2.31AsnVal: 2.31 ± 0.051	0.382AsnTrp: 0.382 ± 0.019	0.596AsnTyr: 0.596 ± 0.023	0.0AsnXaa: 0.0 ± 0.0
Pro	6.967ProAla: 6.967 ± 0.091	0.297ProCys: 0.297 ± 0.016	3.235ProAsp: 3.235 ± 0.057	2.944ProGlu: 2.944 ± 0.054	1.947ProPhe: 1.947 ± 0.045	4.568ProGly: 4.568 ± 0.058	1.086ProHis: 1.086 ± 0.03	2.088ProIle: 2.088 ± 0.046	1.242ProLys: 1.242 ± 0.044	5.378ProLeu: 5.378 ± 0.072	1.321ProMet: 1.321 ± 0.027	1.523ProAsn: 1.523 ± 0.047	2.74ProPro: 2.74 ± 0.072	1.597ProGln: 1.597 ± 0.038	3.774ProArg: 3.774 ± 0.069	3.344ProSer: 3.344 ± 0.058	3.577ProThr: 3.577 ± 0.059	4.858ProVal: 4.858 ± 0.069	0.833ProTrp: 0.833 ± 0.031	1.136ProTyr: 1.136 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	4.062GlnAla: 4.062 ± 0.057	0.232GlnCys: 0.232 ± 0.015	1.361GlnAsp: 1.361 ± 0.036	1.539GlnGlu: 1.539 ± 0.042	1.262GlnPhe: 1.262 ± 0.036	2.573GlnGly: 2.573 ± 0.05	0.816GlnHis: 0.816 ± 0.026	1.392GlnIle: 1.392 ± 0.034	0.81GlnLys: 0.81 ± 0.03	4.153GlnLeu: 4.153 ± 0.064	0.798GlnMet: 0.798 ± 0.025	0.796GlnAsn: 0.796 ± 0.035	1.838GlnPro: 1.838 ± 0.043	1.95GlnGln: 1.95 ± 0.075	3.328GlnArg: 3.328 ± 0.052	1.882GlnSer: 1.882 ± 0.046	1.674GlnThr: 1.674 ± 0.037	2.848GlnVal: 2.848 ± 0.047	0.631GlnTrp: 0.631 ± 0.025	0.858GlnTyr: 0.858 ± 0.029	0.0GlnXaa: 0.0 ± 0.0
Arg	9.337ArgAla: 9.337 ± 0.115	0.487ArgCys: 0.487 ± 0.021	4.637ArgAsp: 4.637 ± 0.071	4.669ArgGlu: 4.669 ± 0.081	2.98ArgPhe: 2.98 ± 0.057	5.93ArgGly: 5.93 ± 0.078	1.525ArgHis: 1.525 ± 0.036	3.591ArgIle: 3.591 ± 0.057	1.706ArgLys: 1.706 ± 0.041	7.969ArgLeu: 7.969 ± 0.097	1.977ArgMet: 1.977 ± 0.041	1.843ArgAsn: 1.843 ± 0.042	3.656ArgPro: 3.656 ± 0.065	2.646ArgGln: 2.646 ± 0.048	6.02ArgArg: 6.02 ± 0.085	4.008ArgSer: 4.008 ± 0.066	4.921ArgThr: 4.921 ± 0.062	6.428ArgVal: 6.428 ± 0.088	1.318ArgTrp: 1.318 ± 0.032	1.982ArgTyr: 1.982 ± 0.04	0.0ArgXaa: 0.0 ± 0.0
Ser	7.407SerAla: 7.407 ± 0.085	0.393SerCys: 0.393 ± 0.023	2.801SerAsp: 2.801 ± 0.043	2.285SerGlu: 2.285 ± 0.041	1.932SerPhe: 1.932 ± 0.042	5.324SerGly: 5.324 ± 0.079	1.05SerHis: 1.05 ± 0.032	2.282SerIle: 2.282 ± 0.049	1.268SerLys: 1.268 ± 0.035	5.921SerLeu: 5.921 ± 0.073	1.358SerMet: 1.358 ± 0.032	1.45SerAsn: 1.45 ± 0.043	3.229SerPro: 3.229 ± 0.058	1.712SerGln: 1.712 ± 0.042	4.128SerArg: 4.128 ± 0.057	3.388SerSer: 3.388 ± 0.066	3.761SerThr: 3.761 ± 0.061	4.869SerVal: 4.869 ± 0.066	0.91SerTrp: 0.91 ± 0.033	1.314SerTyr: 1.314 ± 0.038	0.0SerXaa: 0.0 ± 0.0
Thr	7.503ThrAla: 7.503 ± 0.094	0.394ThrCys: 0.394 ± 0.019	3.208ThrAsp: 3.208 ± 0.053	2.557ThrGlu: 2.557 ± 0.043	2.114ThrPhe: 2.114 ± 0.046	5.788ThrGly: 5.788 ± 0.08	1.193ThrHis: 1.193 ± 0.038	2.702ThrIle: 2.702 ± 0.056	1.412ThrLys: 1.412 ± 0.042	6.88ThrLeu: 6.88 ± 0.083	1.483ThrMet: 1.483 ± 0.037	1.622ThrAsn: 1.622 ± 0.038	4.339ThrPro: 4.339 ± 0.069	1.817ThrGln: 1.817 ± 0.046	4.464ThrArg: 4.464 ± 0.058	3.537ThrSer: 3.537 ± 0.061	4.095ThrThr: 4.095 ± 0.071	5.815ThrVal: 5.815 ± 0.07	0.992ThrTrp: 0.992 ± 0.037	1.319ThrTyr: 1.319 ± 0.038	0.0ThrXaa: 0.0 ± 0.0
Val	10.528ValAla: 10.528 ± 0.109	0.615ValCys: 0.615 ± 0.025	4.383ValAsp: 4.383 ± 0.067	4.332ValGlu: 4.332 ± 0.075	2.554ValPhe: 2.554 ± 0.047	6.634ValGly: 6.634 ± 0.084	1.838ValHis: 1.838 ± 0.047	3.505ValIle: 3.505 ± 0.06	2.021ValLys: 2.021 ± 0.049	8.584ValLeu: 8.584 ± 0.108	1.791ValMet: 1.791 ± 0.037	2.284ValAsn: 2.284 ± 0.05	4.926ValPro: 4.926 ± 0.077	3.174ValGln: 3.174 ± 0.052	7.053ValArg: 7.053 ± 0.099	5.048ValSer: 5.048 ± 0.068	5.405ValThr: 5.405 ± 0.085	7.812ValVal: 7.812 ± 0.103	1.018ValTrp: 1.018 ± 0.032	1.729ValTyr: 1.729 ± 0.045	0.0ValXaa: 0.0 ± 0.0
Trp	1.249TrpAla: 1.249 ± 0.036	0.131TrpCys: 0.131 ± 0.01	0.68TrpAsp: 0.68 ± 0.026	0.627TrpGlu: 0.627 ± 0.023	0.591TrpPhe: 0.591 ± 0.024	1.046TrpGly: 1.046 ± 0.035	0.381TrpHis: 0.381 ± 0.018	0.575TrpIle: 0.575 ± 0.023	0.403TrpLys: 0.403 ± 0.021	1.573TrpLeu: 1.573 ± 0.039	0.434TrpMet: 0.434 ± 0.02	0.479TrpAsn: 0.479 ± 0.023	0.699TrpPro: 0.699 ± 0.027	0.695TrpGln: 0.695 ± 0.024	1.457TrpArg: 1.457 ± 0.042	0.987TrpSer: 0.987 ± 0.035	0.916TrpThr: 0.916 ± 0.033	0.993TrpVal: 0.993 ± 0.031	0.3TrpTrp: 0.3 ± 0.016	0.408TrpTyr: 0.408 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.639TyrAla: 2.639 ± 0.046	0.181TyrCys: 0.181 ± 0.011	1.361TyrAsp: 1.361 ± 0.033	1.116TyrGlu: 1.116 ± 0.029	0.84TyrPhe: 0.84 ± 0.028	2.026TyrGly: 2.026 ± 0.045	0.489TyrHis: 0.489 ± 0.021	0.794TyrIle: 0.794 ± 0.029	0.51TyrLys: 0.51 ± 0.023	2.073TyrLeu: 2.073 ± 0.043	0.405TyrMet: 0.405 ± 0.018	0.633TyrAsn: 0.633 ± 0.028	1.15TyrPro: 1.15 ± 0.032	0.752TyrGln: 0.752 ± 0.026	1.768TyrArg: 1.768 ± 0.04	1.124TyrSer: 1.124 ± 0.037	1.45TyrThr: 1.45 ± 0.038	1.76TyrVal: 1.76 ± 0.038	0.311TyrTrp: 0.311 ± 0.015	0.565TyrTyr: 0.565 ± 0.026	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3388 proteins (1195143 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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