Amino acid dipepetide frequency for Leptolyngbya valderiana BDU 20041

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	12.252AlaAla: 12.252 ± 0.128	1.138AlaCys: 1.138 ± 0.025	6.18AlaAsp: 6.18 ± 0.07	6.979AlaGlu: 6.979 ± 0.094	3.754AlaPhe: 3.754 ± 0.055	8.64AlaGly: 8.64 ± 0.1	1.749AlaHis: 1.749 ± 0.04	6.95AlaIle: 6.95 ± 0.071	2.946AlaLys: 2.946 ± 0.053	11.197AlaLeu: 11.197 ± 0.096	2.662AlaMet: 2.662 ± 0.04	2.904AlaAsn: 2.904 ± 0.058	4.396AlaPro: 4.396 ± 0.063	3.907AlaGln: 3.907 ± 0.056	7.396AlaArg: 7.396 ± 0.086	6.256AlaSer: 6.256 ± 0.069	5.558AlaThr: 5.558 ± 0.066	7.77AlaVal: 7.77 ± 0.07	1.568AlaTrp: 1.568 ± 0.031	2.352AlaTyr: 2.352 ± 0.038	0.0AlaXaa: 0.0 ± 0.0
Cys	0.767CysAla: 0.767 ± 0.019	0.143CysCys: 0.143 ± 0.009	0.689CysAsp: 0.689 ± 0.021	0.516CysGlu: 0.516 ± 0.017	0.342CysPhe: 0.342 ± 0.013	0.873CysGly: 0.873 ± 0.025	0.24CysHis: 0.24 ± 0.013	0.43CysIle: 0.43 ± 0.016	0.208CysLys: 0.208 ± 0.011	0.892CysLeu: 0.892 ± 0.022	0.167CysMet: 0.167 ± 0.009	0.259CysAsn: 0.259 ± 0.012	0.554CysPro: 0.554 ± 0.019	0.394CysGln: 0.394 ± 0.016	0.703CysArg: 0.703 ± 0.019	0.498CysSer: 0.498 ± 0.016	0.421CysThr: 0.421 ± 0.014	0.653CysVal: 0.653 ± 0.019	0.125CysTrp: 0.125 ± 0.008	0.271CysTyr: 0.271 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	6.888AspAla: 6.888 ± 0.072	0.537AspCys: 0.537 ± 0.017	3.794AspAsp: 3.794 ± 0.063	4.001AspGlu: 4.001 ± 0.055	2.462AspPhe: 2.462 ± 0.047	5.703AspGly: 5.703 ± 0.086	0.882AspHis: 0.882 ± 0.027	2.846AspIle: 2.846 ± 0.04	1.359AspLys: 1.359 ± 0.031	6.773AspLeu: 6.773 ± 0.079	0.991AspMet: 0.991 ± 0.026	1.563AspAsn: 1.563 ± 0.033	3.839AspPro: 3.839 ± 0.057	1.451AspGln: 1.451 ± 0.032	7.04AspArg: 7.04 ± 0.083	2.947AspSer: 2.947 ± 0.049	2.837AspThr: 2.837 ± 0.047	4.057AspVal: 4.057 ± 0.057	1.043AspTrp: 1.043 ± 0.027	1.54AspTyr: 1.54 ± 0.033	0.0AspXaa: 0.0 ± 0.0
Glu	7.807GluAla: 7.807 ± 0.081	0.405GluCys: 0.405 ± 0.016	3.541GluAsp: 3.541 ± 0.054	3.824GluGlu: 3.824 ± 0.077	2.337GluPhe: 2.337 ± 0.043	4.437GluGly: 4.437 ± 0.052	1.209GluHis: 1.209 ± 0.025	3.757GluIle: 3.757 ± 0.054	1.986GluLys: 1.986 ± 0.042	6.979GluLeu: 6.979 ± 0.073	1.386GluMet: 1.386 ± 0.029	2.004GluAsn: 2.004 ± 0.037	3.374GluPro: 3.374 ± 0.054	2.664GluGln: 2.664 ± 0.041	5.514GluArg: 5.514 ± 0.066	3.489GluSer: 3.489 ± 0.049	4.036GluThr: 4.036 ± 0.052	4.429GluVal: 4.429 ± 0.05	0.717GluTrp: 0.717 ± 0.02	1.383GluTyr: 1.383 ± 0.032	0.0GluXaa: 0.0 ± 0.0
Phe	3.611PheAla: 3.611 ± 0.05	0.399PheCys: 0.399 ± 0.014	3.201PheAsp: 3.201 ± 0.057	2.607PheGlu: 2.607 ± 0.036	1.473PhePhe: 1.473 ± 0.032	3.417PheGly: 3.417 ± 0.057	0.695PheHis: 0.695 ± 0.024	1.514PheIle: 1.514 ± 0.034	0.906PheLys: 0.906 ± 0.026	3.424PheLeu: 3.424 ± 0.051	0.626PheMet: 0.626 ± 0.02	1.117PheAsn: 1.117 ± 0.028	1.654PhePro: 1.654 ± 0.032	1.408PheGln: 1.408 ± 0.029	2.104PheArg: 2.104 ± 0.036	2.313PheSer: 2.313 ± 0.037	1.822PheThr: 1.822 ± 0.035	2.928PheVal: 2.928 ± 0.043	0.571PheTrp: 0.571 ± 0.019	1.015PheTyr: 1.015 ± 0.024	0.0PheXaa: 0.0 ± 0.0
Gly	7.252GlyAla: 7.252 ± 0.098	0.887GlyCys: 0.887 ± 0.025	5.236GlyAsp: 5.236 ± 0.076	5.208GlyGlu: 5.208 ± 0.06	3.215GlyPhe: 3.215 ± 0.041	6.874GlyGly: 6.874 ± 0.103	1.433GlyHis: 1.433 ± 0.028	4.104GlyIle: 4.104 ± 0.059	2.555GlyLys: 2.555 ± 0.045	8.344GlyLeu: 8.344 ± 0.075	1.814GlyMet: 1.814 ± 0.036	2.511GlyAsn: 2.511 ± 0.054	2.885GlyPro: 2.885 ± 0.051	3.18GlyGln: 3.18 ± 0.044	5.584GlyArg: 5.584 ± 0.07	4.719GlySer: 4.719 ± 0.066	4.389GlyThr: 4.389 ± 0.065	6.217GlyVal: 6.217 ± 0.077	1.349GlyTrp: 1.349 ± 0.031	2.211GlyTyr: 2.211 ± 0.034	0.0GlyXaa: 0.0 ± 0.0
His	2.01HisAla: 2.01 ± 0.04	0.22HisCys: 0.22 ± 0.01	1.062HisAsp: 1.062 ± 0.023	1.118HisGlu: 1.118 ± 0.03	0.686HisPhe: 0.686 ± 0.017	1.439HisGly: 1.439 ± 0.029	0.584HisHis: 0.584 ± 0.026	0.725HisIle: 0.725 ± 0.02	0.437HisLys: 0.437 ± 0.016	2.122HisLeu: 2.122 ± 0.038	0.285HisMet: 0.285 ± 0.012	0.45HisAsn: 0.45 ± 0.015	1.395HisPro: 1.395 ± 0.032	0.767HisGln: 0.767 ± 0.021	1.545HisArg: 1.545 ± 0.03	0.863HisSer: 0.863 ± 0.021	0.816HisThr: 0.816 ± 0.022	1.205HisVal: 1.205 ± 0.028	0.338HisTrp: 0.338 ± 0.013	0.53HisTyr: 0.53 ± 0.019	0.0HisXaa: 0.0 ± 0.0
Ile	6.676IleAla: 6.676 ± 0.065	0.459IleCys: 0.459 ± 0.017	4.13IleAsp: 4.13 ± 0.06	4.333IleGlu: 4.333 ± 0.055	1.725IlePhe: 1.725 ± 0.032	4.165IleGly: 4.165 ± 0.054	0.841IleHis: 0.841 ± 0.024	1.753IleIle: 1.753 ± 0.036	1.087IleLys: 1.087 ± 0.026	4.416IleLeu: 4.416 ± 0.055	0.622IleMet: 0.622 ± 0.017	1.314IleAsn: 1.314 ± 0.029	2.404IlePro: 2.404 ± 0.038	1.547IleGln: 1.547 ± 0.032	2.984IleArg: 2.984 ± 0.043	2.84IleSer: 2.84 ± 0.043	2.309IleThr: 2.309 ± 0.043	4.219IleVal: 4.219 ± 0.052	0.592IleTrp: 0.592 ± 0.019	1.143IleTyr: 1.143 ± 0.027	0.0IleXaa: 0.0 ± 0.0
Lys	2.965LysAla: 2.965 ± 0.052	0.171LysCys: 0.171 ± 0.01	1.433LysAsp: 1.433 ± 0.034	1.391LysGlu: 1.391 ± 0.034	0.934LysPhe: 0.934 ± 0.026	1.83LysGly: 1.83 ± 0.037	0.548LysHis: 0.548 ± 0.018	1.557LysIle: 1.557 ± 0.036	1.136LysLys: 1.136 ± 0.035	3.077LysLeu: 3.077 ± 0.047	0.56LysMet: 0.56 ± 0.019	0.878LysAsn: 0.878 ± 0.024	1.776LysPro: 1.776 ± 0.035	1.261LysGln: 1.261 ± 0.034	2.043LysArg: 2.043 ± 0.033	1.64LysSer: 1.64 ± 0.036	1.864LysThr: 1.864 ± 0.036	1.828LysVal: 1.828 ± 0.039	0.293LysTrp: 0.293 ± 0.012	0.657LysTyr: 0.657 ± 0.02	0.0LysXaa: 0.0 ± 0.0
Leu	12.245LeuAla: 12.245 ± 0.113	0.98LeuCys: 0.98 ± 0.024	7.228LeuAsp: 7.228 ± 0.062	7.5LeuGlu: 7.5 ± 0.075	3.522LeuPhe: 3.522 ± 0.052	8.408LeuGly: 8.408 ± 0.088	1.941LeuHis: 1.941 ± 0.033	4.44LeuIle: 4.44 ± 0.057	3.359LeuLys: 3.359 ± 0.051	10.412LeuLeu: 10.412 ± 0.107	2.021LeuMet: 2.021 ± 0.036	3.014LeuAsn: 3.014 ± 0.045	5.529LeuPro: 5.529 ± 0.059	3.995LeuGln: 3.995 ± 0.063	7.045LeuArg: 7.045 ± 0.065	6.827LeuSer: 6.827 ± 0.07	5.792LeuThr: 5.792 ± 0.059	7.961LeuVal: 7.961 ± 0.073	1.456LeuTrp: 1.456 ± 0.035	2.348LeuTyr: 2.348 ± 0.04	0.0LeuXaa: 0.0 ± 0.0
Met	2.412MetAla: 2.412 ± 0.042	0.141MetCys: 0.141 ± 0.009	0.988MetAsp: 0.988 ± 0.025	1.078MetGlu: 1.078 ± 0.023	0.584MetPhe: 0.584 ± 0.018	1.564MetGly: 1.564 ± 0.034	0.36MetHis: 0.36 ± 0.014	0.773MetIle: 0.773 ± 0.023	0.745MetLys: 0.745 ± 0.021	2.178MetLeu: 2.178 ± 0.039	0.463MetMet: 0.463 ± 0.017	0.557MetAsn: 0.557 ± 0.018	1.202MetPro: 1.202 ± 0.027	0.754MetGln: 0.754 ± 0.022	1.365MetArg: 1.365 ± 0.029	1.368MetSer: 1.368 ± 0.026	1.395MetThr: 1.395 ± 0.031	1.461MetVal: 1.461 ± 0.032	0.181MetTrp: 0.181 ± 0.01	0.318MetTyr: 0.318 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	3.058AsnAla: 3.058 ± 0.048	0.26AsnCys: 0.26 ± 0.012	1.618AsnAsp: 1.618 ± 0.042	1.425AsnGlu: 1.425 ± 0.029	1.142AsnPhe: 1.142 ± 0.026	2.402AsnGly: 2.402 ± 0.047	0.513AsnHis: 0.513 ± 0.018	1.371AsnIle: 1.371 ± 0.03	0.639AsnLys: 0.639 ± 0.021	3.325AsnLeu: 3.325 ± 0.076	0.423AsnMet: 0.423 ± 0.017	0.885AsnAsn: 0.885 ± 0.027	2.111AsnPro: 2.111 ± 0.037	1.103AsnGln: 1.103 ± 0.026	2.015AsnArg: 2.015 ± 0.035	1.546AsnSer: 1.546 ± 0.034	1.451AsnThr: 1.451 ± 0.032	1.94AsnVal: 1.94 ± 0.032	0.483AsnTrp: 0.483 ± 0.015	0.729AsnTyr: 0.729 ± 0.024	0.0AsnXaa: 0.0 ± 0.0
Pro	4.998ProAla: 4.998 ± 0.068	0.358ProCys: 0.358 ± 0.015	3.871ProAsp: 3.871 ± 0.05	4.359ProGlu: 4.359 ± 0.051	1.841ProPhe: 1.841 ± 0.029	4.302ProGly: 4.302 ± 0.058	1.001ProHis: 1.001 ± 0.025	2.571ProIle: 2.571 ± 0.039	1.572ProLys: 1.572 ± 0.031	4.873ProLeu: 4.873 ± 0.059	1.104ProMet: 1.104 ± 0.027	1.597ProAsn: 1.597 ± 0.03	2.923ProPro: 2.923 ± 0.047	2.176ProGln: 2.176 ± 0.038	2.812ProArg: 2.812 ± 0.046	3.132ProSer: 3.132 ± 0.044	3.07ProThr: 3.07 ± 0.052	3.884ProVal: 3.884 ± 0.045	0.761ProTrp: 0.761 ± 0.022	1.152ProTyr: 1.152 ± 0.026	0.0ProXaa: 0.0 ± 0.0
Gln	4.412GlnAla: 4.412 ± 0.063	0.261GlnCys: 0.261 ± 0.011	1.734GlnAsp: 1.734 ± 0.032	2.037GlnGlu: 2.037 ± 0.042	1.42GlnPhe: 1.42 ± 0.027	2.639GlnGly: 2.639 ± 0.037	0.801GlnHis: 0.801 ± 0.02	2.151GlnIle: 2.151 ± 0.035	1.176GlnLys: 1.176 ± 0.027	4.392GlnLeu: 4.392 ± 0.053	0.828GlnMet: 0.828 ± 0.025	1.148GlnAsn: 1.148 ± 0.024	2.081GlnPro: 2.081 ± 0.037	2.189GlnGln: 2.189 ± 0.058	3.039GlnArg: 3.039 ± 0.044	2.079GlnSer: 2.079 ± 0.032	2.323GlnThr: 2.323 ± 0.038	2.761GlnVal: 2.761 ± 0.035	0.621GlnTrp: 0.621 ± 0.019	0.841GlnTyr: 0.841 ± 0.023	0.0GlnXaa: 0.0 ± 0.0
Arg	7.022ArgAla: 7.022 ± 0.09	0.667ArgCys: 0.667 ± 0.021	4.514ArgAsp: 4.514 ± 0.05	4.747ArgGlu: 4.747 ± 0.06	2.912ArgPhe: 2.912 ± 0.047	4.867ArgGly: 4.867 ± 0.057	1.536ArgHis: 1.536 ± 0.03	3.597ArgIle: 3.597 ± 0.04	1.928ArgLys: 1.928 ± 0.044	8.364ArgLeu: 8.364 ± 0.083	1.47ArgMet: 1.47 ± 0.028	1.868ArgAsn: 1.868 ± 0.032	3.559ArgPro: 3.559 ± 0.05	3.524ArgGln: 3.524 ± 0.051	5.619ArgArg: 5.619 ± 0.074	4.512ArgSer: 4.512 ± 0.059	3.627ArgThr: 3.627 ± 0.048	5.472ArgVal: 5.472 ± 0.065	1.277ArgTrp: 1.277 ± 0.028	1.968ArgTyr: 1.968 ± 0.033	0.0ArgXaa: 0.0 ± 0.0
Ser	5.435SerAla: 5.435 ± 0.056	0.499SerCys: 0.499 ± 0.019	3.713SerAsp: 3.713 ± 0.053	3.656SerGlu: 3.656 ± 0.058	2.144SerPhe: 2.144 ± 0.037	5.265SerGly: 5.265 ± 0.067	1.123SerHis: 1.123 ± 0.021	3.12SerIle: 3.12 ± 0.039	1.514SerLys: 1.514 ± 0.034	6.197SerLeu: 6.197 ± 0.064	1.242SerMet: 1.242 ± 0.028	1.727SerAsn: 1.727 ± 0.037	3.406SerPro: 3.406 ± 0.053	2.505SerGln: 2.505 ± 0.041	3.878SerArg: 3.878 ± 0.044	3.627SerSer: 3.627 ± 0.049	3.114SerThr: 3.114 ± 0.051	4.152SerVal: 4.152 ± 0.053	0.838SerTrp: 0.838 ± 0.022	1.295SerTyr: 1.295 ± 0.026	0.0SerXaa: 0.0 ± 0.0
Thr	5.381ThrAla: 5.381 ± 0.058	0.449ThrCys: 0.449 ± 0.015	2.974ThrAsp: 2.974 ± 0.043	3.013ThrGlu: 3.013 ± 0.048	1.87ThrPhe: 1.87 ± 0.033	4.62ThrGly: 4.62 ± 0.072	1.033ThrHis: 1.033 ± 0.025	3.074ThrIle: 3.074 ± 0.047	1.158ThrLys: 1.158 ± 0.029	6.398ThrLeu: 6.398 ± 0.064	0.952ThrMet: 0.952 ± 0.023	1.411ThrAsn: 1.411 ± 0.033	3.7ThrPro: 3.7 ± 0.049	1.994ThrGln: 1.994 ± 0.031	3.316ThrArg: 3.316 ± 0.047	3.086ThrSer: 3.086 ± 0.05	3.072ThrThr: 3.072 ± 0.042	4.407ThrVal: 4.407 ± 0.054	0.726ThrTrp: 0.726 ± 0.018	1.298ThrTyr: 1.298 ± 0.029	0.0ThrXaa: 0.0 ± 0.0
Val	7.927ValAla: 7.927 ± 0.082	0.741ValCys: 0.741 ± 0.021	4.382ValAsp: 4.382 ± 0.051	5.178ValGlu: 5.178 ± 0.056	2.833ValPhe: 2.833 ± 0.043	5.627ValGly: 5.627 ± 0.063	1.238ValHis: 1.238 ± 0.028	3.143ValIle: 3.143 ± 0.045	2.101ValLys: 2.101 ± 0.041	8.137ValLeu: 8.137 ± 0.073	1.541ValMet: 1.541 ± 0.027	1.991ValAsn: 1.991 ± 0.034	3.723ValPro: 3.723 ± 0.05	2.269ValGln: 2.269 ± 0.04	5.761ValArg: 5.761 ± 0.065	4.621ValSer: 4.621 ± 0.059	4.023ValThr: 4.023 ± 0.054	6.194ValVal: 6.194 ± 0.073	1.002ValTrp: 1.002 ± 0.024	1.744ValTyr: 1.744 ± 0.034	0.0ValXaa: 0.0 ± 0.0
Trp	1.167TrpAla: 1.167 ± 0.026	0.151TrpCys: 0.151 ± 0.009	0.675TrpAsp: 0.675 ± 0.024	0.806TrpGlu: 0.806 ± 0.022	0.596TrpPhe: 0.596 ± 0.018	0.964TrpGly: 0.964 ± 0.025	0.344TrpHis: 0.344 ± 0.014	0.743TrpIle: 0.743 ± 0.023	0.447TrpLys: 0.447 ± 0.017	1.909TrpLeu: 1.909 ± 0.038	0.392TrpMet: 0.392 ± 0.015	0.527TrpAsn: 0.527 ± 0.018	0.579TrpPro: 0.579 ± 0.017	0.817TrpGln: 0.817 ± 0.021	1.114TrpArg: 1.114 ± 0.027	0.867TrpSer: 0.867 ± 0.021	0.842TrpThr: 0.842 ± 0.02	1.048TrpVal: 1.048 ± 0.024	0.264TrpTrp: 0.264 ± 0.011	0.346TrpTyr: 0.346 ± 0.014	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.268TyrAla: 2.268 ± 0.034	0.275TyrCys: 0.275 ± 0.011	1.591TyrAsp: 1.591 ± 0.03	1.5TyrGlu: 1.5 ± 0.031	1.012TyrPhe: 1.012 ± 0.026	1.933TyrGly: 1.933 ± 0.028	0.528TyrHis: 0.528 ± 0.019	0.941TyrIle: 0.941 ± 0.022	0.581TyrLys: 0.581 ± 0.02	2.615TyrLeu: 2.615 ± 0.039	0.337TyrMet: 0.337 ± 0.013	0.714TyrAsn: 0.714 ± 0.021	1.27TyrPro: 1.27 ± 0.03	1.027TyrGln: 1.027 ± 0.028	2.174TyrArg: 2.174 ± 0.039	1.224TyrSer: 1.224 ± 0.026	1.169TyrThr: 1.169 ± 0.028	1.589TyrVal: 1.589 ± 0.034	0.393TyrTrp: 0.393 ± 0.016	0.712TyrTyr: 0.712 ± 0.021	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5400 proteins (1905942 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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