Amino acid dipepetide frequency for Grapevine Cabernet Sauvignon reovirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.542AlaAla: 3.542 ± 0.582
1.138AlaCys: 1.138 ± 0.249
2.403AlaAsp: 2.403 ± 0.341
4.933AlaGlu: 4.933 ± 0.646
2.909AlaPhe: 2.909 ± 0.509
3.036AlaGly: 3.036 ± 0.435
1.265AlaHis: 1.265 ± 0.437
4.427AlaIle: 4.427 ± 0.894
2.403AlaLys: 2.403 ± 0.353
5.059AlaLeu: 5.059 ± 1.016
2.656AlaMet: 2.656 ± 0.451
4.048AlaAsn: 4.048 ± 0.596
1.771AlaPro: 1.771 ± 0.431
3.289AlaGln: 3.289 ± 0.327
4.427AlaArg: 4.427 ± 0.368
5.186AlaSer: 5.186 ± 0.714
3.036AlaThr: 3.036 ± 0.491
3.668AlaVal: 3.668 ± 0.835
0.759AlaTrp: 0.759 ± 0.217
3.036AlaTyr: 3.036 ± 0.762
0.0AlaXaa: 0.0 ± 0.0
Cys
1.138CysAla: 1.138 ± 0.381
0.379CysCys: 0.379 ± 0.236
1.391CysAsp: 1.391 ± 0.219
1.012CysGlu: 1.012 ± 0.322
1.265CysPhe: 1.265 ± 0.374
1.518CysGly: 1.518 ± 0.194
0.379CysHis: 0.379 ± 0.18
0.253CysIle: 0.253 ± 0.16
0.632CysLys: 0.632 ± 0.199
1.138CysLeu: 1.138 ± 0.173
0.632CysMet: 0.632 ± 0.38
0.885CysAsn: 0.885 ± 0.34
1.012CysPro: 1.012 ± 0.381
0.885CysGln: 0.885 ± 0.304
0.506CysArg: 0.506 ± 0.153
1.771CysSer: 1.771 ± 0.384
0.632CysThr: 0.632 ± 0.35
0.885CysVal: 0.885 ± 0.3
0.253CysTrp: 0.253 ± 0.162
0.632CysTyr: 0.632 ± 0.261
0.0CysXaa: 0.0 ± 0.0
Asp
3.162AspAla: 3.162 ± 0.512
0.506AspCys: 0.506 ± 0.219
3.668AspAsp: 3.668 ± 0.722
3.921AspGlu: 3.921 ± 0.849
3.668AspPhe: 3.668 ± 0.506
2.783AspGly: 2.783 ± 0.438
1.012AspHis: 1.012 ± 0.337
3.542AspIle: 3.542 ± 0.789
2.783AspLys: 2.783 ± 0.448
4.301AspLeu: 4.301 ± 0.475
1.391AspMet: 1.391 ± 0.352
1.644AspAsn: 1.644 ± 0.512
3.289AspPro: 3.289 ± 0.696
3.542AspGln: 3.542 ± 1.185
3.668AspArg: 3.668 ± 0.671
4.048AspSer: 4.048 ± 0.654
2.783AspThr: 2.783 ± 0.536
4.806AspVal: 4.806 ± 0.65
0.759AspTrp: 0.759 ± 0.224
2.656AspTyr: 2.656 ± 0.395
0.0AspXaa: 0.0 ± 0.0
Glu
4.174GluAla: 4.174 ± 0.534
1.012GluCys: 1.012 ± 0.278
4.68GluAsp: 4.68 ± 0.757
3.289GluGlu: 3.289 ± 0.626
2.15GluPhe: 2.15 ± 0.425
3.289GluGly: 3.289 ± 0.649
0.885GluHis: 0.885 ± 0.291
4.427GluIle: 4.427 ± 0.403
3.795GluLys: 3.795 ± 0.803
5.565GluLeu: 5.565 ± 0.462
1.138GluMet: 1.138 ± 0.374
2.403GluAsn: 2.403 ± 0.628
2.783GluPro: 2.783 ± 0.551
2.53GluGln: 2.53 ± 0.421
3.162GluArg: 3.162 ± 0.584
3.921GluSer: 3.921 ± 0.98
3.036GluThr: 3.036 ± 0.934
5.059GluVal: 5.059 ± 0.59
0.759GluTrp: 0.759 ± 0.238
2.656GluTyr: 2.656 ± 0.365
0.0GluXaa: 0.0 ± 0.0
Phe
2.909PheAla: 2.909 ± 0.608
1.012PheCys: 1.012 ± 0.271
3.415PheAsp: 3.415 ± 0.881
2.403PheGlu: 2.403 ± 0.413
0.885PhePhe: 0.885 ± 0.285
2.53PheGly: 2.53 ± 0.642
1.138PheHis: 1.138 ± 0.438
1.644PheIle: 1.644 ± 0.354
1.897PheLys: 1.897 ± 0.409
3.289PheLeu: 3.289 ± 0.291
1.138PheMet: 1.138 ± 0.319
3.289PheAsn: 3.289 ± 0.466
2.15PhePro: 2.15 ± 0.37
3.036PheGln: 3.036 ± 0.619
1.644PheArg: 1.644 ± 0.6
3.795PheSer: 3.795 ± 0.549
3.036PheThr: 3.036 ± 0.565
2.403PheVal: 2.403 ± 0.332
0.506PheTrp: 0.506 ± 0.21
1.138PheTyr: 1.138 ± 0.264
0.0PheXaa: 0.0 ± 0.0
Gly
4.933GlyAla: 4.933 ± 0.742
0.506GlyCys: 0.506 ± 0.23
2.909GlyAsp: 2.909 ± 0.443
3.036GlyGlu: 3.036 ± 0.465
2.277GlyPhe: 2.277 ± 0.519
1.897GlyGly: 1.897 ± 0.397
0.632GlyHis: 0.632 ± 0.161
3.921GlyIle: 3.921 ± 0.648
2.15GlyLys: 2.15 ± 0.571
7.589GlyLeu: 7.589 ± 0.669
1.644GlyMet: 1.644 ± 0.562
2.909GlyAsn: 2.909 ± 0.493
1.518GlyPro: 1.518 ± 0.35
1.138GlyGln: 1.138 ± 0.344
3.795GlyArg: 3.795 ± 0.5
2.783GlySer: 2.783 ± 0.36
3.542GlyThr: 3.542 ± 0.722
3.542GlyVal: 3.542 ± 0.594
0.632GlyTrp: 0.632 ± 0.23
1.138GlyTyr: 1.138 ± 0.428
0.0GlyXaa: 0.0 ± 0.0
His
1.012HisAla: 1.012 ± 0.188
0.379HisCys: 0.379 ± 0.162
0.632HisAsp: 0.632 ± 0.269
1.012HisGlu: 1.012 ± 0.425
0.632HisPhe: 0.632 ± 0.132
1.771HisGly: 1.771 ± 0.305
0.506HisHis: 0.506 ± 0.301
0.759HisIle: 0.759 ± 0.241
0.379HisLys: 0.379 ± 0.182
1.138HisLeu: 1.138 ± 0.198
0.632HisMet: 0.632 ± 0.218
1.265HisAsn: 1.265 ± 0.294
1.897HisPro: 1.897 ± 0.443
0.759HisGln: 0.759 ± 0.252
0.759HisArg: 0.759 ± 0.27
1.897HisSer: 1.897 ± 0.414
1.012HisThr: 1.012 ± 0.44
1.391HisVal: 1.391 ± 0.314
0.379HisTrp: 0.379 ± 0.211
0.632HisTyr: 0.632 ± 0.181
0.0HisXaa: 0.0 ± 0.0
Ile
4.301IleAla: 4.301 ± 0.575
1.012IleCys: 1.012 ± 0.228
3.415IleAsp: 3.415 ± 0.566
3.036IleGlu: 3.036 ± 0.416
3.542IlePhe: 3.542 ± 0.422
2.909IleGly: 2.909 ± 0.624
1.138IleHis: 1.138 ± 0.412
3.415IleIle: 3.415 ± 0.594
3.542IleLys: 3.542 ± 0.402
6.324IleLeu: 6.324 ± 0.976
1.644IleMet: 1.644 ± 0.375
2.656IleAsn: 2.656 ± 0.348
4.427IlePro: 4.427 ± 0.906
3.542IleGln: 3.542 ± 0.504
3.542IleArg: 3.542 ± 0.601
5.312IleSer: 5.312 ± 0.638
4.68IleThr: 4.68 ± 0.44
4.554IleVal: 4.554 ± 0.667
0.379IleTrp: 0.379 ± 0.159
1.518IleTyr: 1.518 ± 0.308
0.0IleXaa: 0.0 ± 0.0
Lys
4.301LysAla: 4.301 ± 0.504
0.632LysCys: 0.632 ± 0.245
2.53LysAsp: 2.53 ± 0.403
2.277LysGlu: 2.277 ± 0.385
1.265LysPhe: 1.265 ± 0.321
2.277LysGly: 2.277 ± 0.675
0.759LysHis: 0.759 ± 0.344
3.921LysIle: 3.921 ± 0.551
4.048LysLys: 4.048 ± 0.5
5.186LysLeu: 5.186 ± 1.006
1.265LysMet: 1.265 ± 0.515
2.53LysAsn: 2.53 ± 0.648
2.15LysPro: 2.15 ± 0.549
1.771LysGln: 1.771 ± 0.364
2.024LysArg: 2.024 ± 0.495
3.921LysSer: 3.921 ± 0.547
3.162LysThr: 3.162 ± 0.625
3.289LysVal: 3.289 ± 0.687
0.885LysTrp: 0.885 ± 0.328
1.771LysTyr: 1.771 ± 0.437
0.0LysXaa: 0.0 ± 0.0
Leu
5.439LeuAla: 5.439 ± 0.876
1.265LeuCys: 1.265 ± 0.272
6.071LeuAsp: 6.071 ± 0.777
6.071LeuGlu: 6.071 ± 0.948
3.542LeuPhe: 3.542 ± 0.517
5.439LeuGly: 5.439 ± 0.727
2.024LeuHis: 2.024 ± 0.373
6.071LeuIle: 6.071 ± 0.581
5.439LeuLys: 5.439 ± 1.02
8.348LeuLeu: 8.348 ± 1.31
1.138LeuMet: 1.138 ± 0.345
3.795LeuAsn: 3.795 ± 0.849
5.692LeuPro: 5.692 ± 0.885
2.909LeuGln: 2.909 ± 0.473
6.198LeuArg: 6.198 ± 0.618
9.107LeuSer: 9.107 ± 0.755
6.198LeuThr: 6.198 ± 0.743
4.68LeuVal: 4.68 ± 0.747
1.012LeuTrp: 1.012 ± 0.295
3.036LeuTyr: 3.036 ± 0.691
0.0LeuXaa: 0.0 ± 0.0
Met
2.024MetAla: 2.024 ± 0.416
0.632MetCys: 0.632 ± 0.2
1.265MetAsp: 1.265 ± 0.405
1.391MetGlu: 1.391 ± 0.485
1.138MetPhe: 1.138 ± 0.309
1.518MetGly: 1.518 ± 0.273
0.0MetHis: 0.0 ± 0.0
2.15MetIle: 2.15 ± 0.567
0.885MetLys: 0.885 ± 0.263
2.53MetLeu: 2.53 ± 0.594
0.759MetMet: 0.759 ± 0.192
1.265MetAsn: 1.265 ± 0.236
1.391MetPro: 1.391 ± 0.383
0.632MetGln: 0.632 ± 0.196
1.012MetArg: 1.012 ± 0.559
3.162MetSer: 3.162 ± 0.467
0.885MetThr: 0.885 ± 0.307
1.771MetVal: 1.771 ± 0.483
0.632MetTrp: 0.632 ± 0.261
1.265MetTyr: 1.265 ± 0.208
0.0MetXaa: 0.0 ± 0.0
Asn
2.403AsnAla: 2.403 ± 0.475
1.012AsnCys: 1.012 ± 0.323
2.656AsnAsp: 2.656 ± 0.564
3.415AsnGlu: 3.415 ± 0.552
1.897AsnPhe: 1.897 ± 0.423
2.277AsnGly: 2.277 ± 0.598
1.138AsnHis: 1.138 ± 0.348
4.554AsnIle: 4.554 ± 0.787
1.265AsnLys: 1.265 ± 0.34
3.289AsnLeu: 3.289 ± 0.883
1.012AsnMet: 1.012 ± 0.23
1.138AsnAsn: 1.138 ± 0.309
2.909AsnPro: 2.909 ± 0.71
2.403AsnGln: 2.403 ± 0.438
2.783AsnArg: 2.783 ± 0.526
3.795AsnSer: 3.795 ± 0.665
2.277AsnThr: 2.277 ± 0.457
3.036AsnVal: 3.036 ± 0.691
0.759AsnTrp: 0.759 ± 0.187
1.265AsnTyr: 1.265 ± 0.419
0.0AsnXaa: 0.0 ± 0.0
Pro
3.289ProAla: 3.289 ± 0.774
0.885ProCys: 0.885 ± 0.31
2.403ProAsp: 2.403 ± 0.476
2.909ProGlu: 2.909 ± 0.738
2.909ProPhe: 2.909 ± 0.464
2.656ProGly: 2.656 ± 0.615
0.885ProHis: 0.885 ± 0.273
2.403ProIle: 2.403 ± 0.425
2.277ProLys: 2.277 ± 0.395
4.048ProLeu: 4.048 ± 0.499
1.012ProMet: 1.012 ± 0.341
2.53ProAsn: 2.53 ± 0.292
2.53ProPro: 2.53 ± 0.6
2.656ProGln: 2.656 ± 0.743
3.289ProArg: 3.289 ± 0.656
4.68ProSer: 4.68 ± 0.598
4.806ProThr: 4.806 ± 0.799
2.656ProVal: 2.656 ± 0.473
0.379ProTrp: 0.379 ± 0.191
1.771ProTyr: 1.771 ± 0.425
0.126ProXaa: 0.126 ± 0.129
Gln
2.403GlnAla: 2.403 ± 0.498
0.632GlnCys: 0.632 ± 0.242
2.15GlnAsp: 2.15 ± 0.525
2.656GlnGlu: 2.656 ± 0.342
1.897GlnPhe: 1.897 ± 0.507
2.403GlnGly: 2.403 ± 0.691
1.138GlnHis: 1.138 ± 0.219
3.289GlnIle: 3.289 ± 0.589
2.15GlnLys: 2.15 ± 0.316
3.795GlnLeu: 3.795 ± 0.747
0.759GlnMet: 0.759 ± 0.279
2.15GlnAsn: 2.15 ± 0.673
1.391GlnPro: 1.391 ± 0.418
1.518GlnGln: 1.518 ± 0.535
2.53GlnArg: 2.53 ± 0.464
4.554GlnSer: 4.554 ± 0.801
2.53GlnThr: 2.53 ± 0.532
2.403GlnVal: 2.403 ± 0.554
0.253GlnTrp: 0.253 ± 0.162
0.759GlnTyr: 0.759 ± 0.203
0.0GlnXaa: 0.0 ± 0.0
Arg
4.048ArgAla: 4.048 ± 0.543
0.885ArgCys: 0.885 ± 0.224
2.403ArgAsp: 2.403 ± 0.678
3.542ArgGlu: 3.542 ± 0.519
2.15ArgPhe: 2.15 ± 0.401
2.53ArgGly: 2.53 ± 0.749
0.885ArgHis: 0.885 ± 0.391
3.162ArgIle: 3.162 ± 0.371
2.024ArgLys: 2.024 ± 0.43
6.198ArgLeu: 6.198 ± 0.76
2.024ArgMet: 2.024 ± 0.53
1.897ArgAsn: 1.897 ± 0.475
2.909ArgPro: 2.909 ± 0.714
1.518ArgGln: 1.518 ± 0.627
3.542ArgArg: 3.542 ± 0.564
4.554ArgSer: 4.554 ± 0.776
2.783ArgThr: 2.783 ± 0.459
5.312ArgVal: 5.312 ± 0.858
0.885ArgTrp: 0.885 ± 0.347
1.897ArgTyr: 1.897 ± 0.384
0.0ArgXaa: 0.0 ± 0.0
Ser
3.542SerAla: 3.542 ± 0.508
1.897SerCys: 1.897 ± 0.281
5.692SerAsp: 5.692 ± 0.589
5.186SerGlu: 5.186 ± 0.677
3.162SerPhe: 3.162 ± 0.326
4.427SerGly: 4.427 ± 0.832
1.644SerHis: 1.644 ± 0.283
5.312SerIle: 5.312 ± 0.743
3.921SerLys: 3.921 ± 0.517
7.716SerLeu: 7.716 ± 0.874
2.53SerMet: 2.53 ± 0.508
2.909SerAsn: 2.909 ± 0.501
3.921SerPro: 3.921 ± 0.78
2.909SerGln: 2.909 ± 0.446
4.554SerArg: 4.554 ± 0.775
7.842SerSer: 7.842 ± 0.848
4.806SerThr: 4.806 ± 0.628
6.451SerVal: 6.451 ± 0.831
1.644SerTrp: 1.644 ± 0.341
3.668SerTyr: 3.668 ± 0.623
0.0SerXaa: 0.0 ± 0.0
Thr
3.162ThrAla: 3.162 ± 0.636
1.138ThrCys: 1.138 ± 0.333
3.921ThrAsp: 3.921 ± 0.616
2.656ThrGlu: 2.656 ± 0.427
2.656ThrPhe: 2.656 ± 0.762
3.542ThrGly: 3.542 ± 0.899
1.391ThrHis: 1.391 ± 0.367
4.806ThrIle: 4.806 ± 0.83
4.301ThrLys: 4.301 ± 0.452
6.577ThrLeu: 6.577 ± 1.172
1.644ThrMet: 1.644 ± 0.58
3.289ThrAsn: 3.289 ± 0.545
2.783ThrPro: 2.783 ± 0.372
1.644ThrGln: 1.644 ± 0.458
3.036ThrArg: 3.036 ± 0.583
3.668ThrSer: 3.668 ± 0.781
3.921ThrThr: 3.921 ± 0.918
3.289ThrVal: 3.289 ± 0.615
0.885ThrTrp: 0.885 ± 0.293
2.403ThrTyr: 2.403 ± 0.484
0.0ThrXaa: 0.0 ± 0.0
Val
3.921ValAla: 3.921 ± 0.707
1.012ValCys: 1.012 ± 0.547
3.162ValAsp: 3.162 ± 0.543
5.186ValGlu: 5.186 ± 0.736
2.656ValPhe: 2.656 ± 0.405
3.289ValGly: 3.289 ± 0.51
1.012ValHis: 1.012 ± 0.341
4.301ValIle: 4.301 ± 0.619
3.921ValLys: 3.921 ± 0.406
5.692ValLeu: 5.692 ± 0.553
2.277ValMet: 2.277 ± 0.584
2.403ValAsn: 2.403 ± 0.544
4.427ValPro: 4.427 ± 0.816
2.656ValGln: 2.656 ± 0.817
2.909ValArg: 2.909 ± 0.442
6.324ValSer: 6.324 ± 1.154
4.68ValThr: 4.68 ± 0.438
3.036ValVal: 3.036 ± 0.668
0.506ValTrp: 0.506 ± 0.23
2.277ValTyr: 2.277 ± 0.381
0.0ValXaa: 0.0 ± 0.0
Trp
0.759TrpAla: 0.759 ± 0.502
0.253TrpCys: 0.253 ± 0.145
0.885TrpAsp: 0.885 ± 0.28
0.885TrpGlu: 0.885 ± 0.265
0.379TrpPhe: 0.379 ± 0.182
0.379TrpGly: 0.379 ± 0.172
0.126TrpHis: 0.126 ± 0.11
0.506TrpIle: 0.506 ± 0.224
0.885TrpLys: 0.885 ± 0.164
1.518TrpLeu: 1.518 ± 0.41
0.253TrpMet: 0.253 ± 0.136
0.885TrpAsn: 0.885 ± 0.351
0.253TrpPro: 0.253 ± 0.152
0.632TrpGln: 0.632 ± 0.3
0.379TrpArg: 0.379 ± 0.163
1.138TrpSer: 1.138 ± 0.368
0.506TrpThr: 0.506 ± 0.216
1.518TrpVal: 1.518 ± 0.763
0.0TrpTrp: 0.0 ± 0.0
0.632TrpTyr: 0.632 ± 0.274
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.53TyrAla: 2.53 ± 0.414
1.012TyrCys: 1.012 ± 0.341
2.277TyrAsp: 2.277 ± 0.646
1.897TyrGlu: 1.897 ± 0.347
2.277TyrPhe: 2.277 ± 0.61
1.771TyrGly: 1.771 ± 0.298
0.885TyrHis: 0.885 ± 0.214
2.024TyrIle: 2.024 ± 0.287
1.265TyrLys: 1.265 ± 0.508
4.174TyrLeu: 4.174 ± 0.72
0.759TyrMet: 0.759 ± 0.23
1.391TyrAsn: 1.391 ± 0.478
1.897TyrPro: 1.897 ± 0.383
1.391TyrGln: 1.391 ± 0.345
1.391TyrArg: 1.391 ± 0.254
2.277TyrSer: 2.277 ± 0.466
2.403TyrThr: 2.403 ± 0.802
2.024TyrVal: 2.024 ± 0.528
0.506TyrTrp: 0.506 ± 0.31
1.897TyrTyr: 1.897 ± 0.65
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.126XaaGly: 0.126 ± 0.129
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 11 proteins (7907 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski