Amino acid dipepetide frequency for Hornefia porci

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.459AlaAla: 9.459 ± 0.173	1.206AlaCys: 1.206 ± 0.042	5.093AlaAsp: 5.093 ± 0.082	6.847AlaGlu: 6.847 ± 0.145	3.175AlaPhe: 3.175 ± 0.071	7.436AlaGly: 7.436 ± 0.134	1.23AlaHis: 1.23 ± 0.042	4.714AlaIle: 4.714 ± 0.09	4.3AlaLys: 4.3 ± 0.106	7.389AlaLeu: 7.389 ± 0.1	2.667AlaMet: 2.667 ± 0.064	2.338AlaAsn: 2.338 ± 0.051	2.438AlaPro: 2.438 ± 0.061	2.285AlaGln: 2.285 ± 0.071	4.337AlaArg: 4.337 ± 0.088	4.421AlaSer: 4.421 ± 0.106	3.438AlaThr: 3.438 ± 0.071	7.029AlaVal: 7.029 ± 0.101	0.658AlaTrp: 0.658 ± 0.029	2.601AlaTyr: 2.601 ± 0.057	0.0AlaXaa: 0.0 ± 0.0
Cys	1.163CysAla: 1.163 ± 0.042	0.355CysCys: 0.355 ± 0.025	0.972CysAsp: 0.972 ± 0.033	0.953CysGlu: 0.953 ± 0.039	0.588CysPhe: 0.588 ± 0.03	1.669CysGly: 1.669 ± 0.054	0.277CysHis: 0.277 ± 0.018	0.978CysIle: 0.978 ± 0.031	0.552CysLys: 0.552 ± 0.028	1.085CysLeu: 1.085 ± 0.039	0.384CysMet: 0.384 ± 0.023	0.483CysAsn: 0.483 ± 0.022	0.685CysPro: 0.685 ± 0.035	0.289CysGln: 0.289 ± 0.016	1.094CysArg: 1.094 ± 0.041	0.894CysSer: 0.894 ± 0.033	0.755CysThr: 0.755 ± 0.036	1.099CysVal: 1.099 ± 0.038	0.137CysTrp: 0.137 ± 0.015	0.552CysTyr: 0.552 ± 0.031	0.0CysXaa: 0.0 ± 0.0
Asp	4.89AspAla: 4.89 ± 0.1	0.877AspCys: 0.877 ± 0.033	3.092AspAsp: 3.092 ± 0.068	4.65AspGlu: 4.65 ± 0.086	2.788AspPhe: 2.788 ± 0.062	5.036AspGly: 5.036 ± 0.103	0.96AspHis: 0.96 ± 0.034	4.298AspIle: 4.298 ± 0.073	3.276AspLys: 3.276 ± 0.088	4.985AspLeu: 4.985 ± 0.092	1.888AspMet: 1.888 ± 0.047	1.953AspAsn: 1.953 ± 0.056	2.513AspPro: 2.513 ± 0.062	1.344AspGln: 1.344 ± 0.043	3.857AspArg: 3.857 ± 0.087	3.335AspSer: 3.335 ± 0.071	3.059AspThr: 3.059 ± 0.067	3.901AspVal: 3.901 ± 0.067	0.559AspTrp: 0.559 ± 0.028	2.605AspTyr: 2.605 ± 0.065	0.0AspXaa: 0.0 ± 0.0
Glu	5.86GluAla: 5.86 ± 0.112	0.783GluCys: 0.783 ± 0.036	4.414GluAsp: 4.414 ± 0.084	6.543GluGlu: 6.543 ± 0.12	2.377GluPhe: 2.377 ± 0.055	4.437GluGly: 4.437 ± 0.085	1.483GluHis: 1.483 ± 0.052	5.651GluIle: 5.651 ± 0.102	5.829GluLys: 5.829 ± 0.098	6.577GluLeu: 6.577 ± 0.112	2.389GluMet: 2.389 ± 0.057	3.631GluAsn: 3.631 ± 0.07	2.199GluPro: 2.199 ± 0.055	2.632GluGln: 2.632 ± 0.057	3.991GluArg: 3.991 ± 0.084	3.314GluSer: 3.314 ± 0.076	3.935GluThr: 3.935 ± 0.088	4.02GluVal: 4.02 ± 0.086	0.556GluTrp: 0.556 ± 0.03	2.923GluTyr: 2.923 ± 0.067	0.0GluXaa: 0.0 ± 0.0
Phe	3.063PheAla: 3.063 ± 0.067	0.743PheCys: 0.743 ± 0.035	2.525PheAsp: 2.525 ± 0.058	2.29PheGlu: 2.29 ± 0.055	1.606PhePhe: 1.606 ± 0.053	3.144PheGly: 3.144 ± 0.063	0.756PheHis: 0.756 ± 0.038	2.385PheIle: 2.385 ± 0.06	1.456PheLys: 1.456 ± 0.044	3.345PheLeu: 3.345 ± 0.078	1.071PheMet: 1.071 ± 0.041	1.446PheAsn: 1.446 ± 0.044	1.399PhePro: 1.399 ± 0.045	0.999PheGln: 0.999 ± 0.034	2.615PheArg: 2.615 ± 0.06	2.688PheSer: 2.688 ± 0.061	2.265PheThr: 2.265 ± 0.065	2.94PheVal: 2.94 ± 0.07	0.37PheTrp: 0.37 ± 0.021	1.461PheTyr: 1.461 ± 0.049	0.0PheXaa: 0.0 ± 0.0
Gly	5.98GlyAla: 5.98 ± 0.106	1.27GlyCys: 1.27 ± 0.045	4.289GlyAsp: 4.289 ± 0.085	5.18GlyGlu: 5.18 ± 0.094	3.175GlyPhe: 3.175 ± 0.075	5.895GlyGly: 5.895 ± 0.098	1.383GlyHis: 1.383 ± 0.042	5.998GlyIle: 5.998 ± 0.105	5.534GlyLys: 5.534 ± 0.108	6.067GlyLeu: 6.067 ± 0.083	2.497GlyMet: 2.497 ± 0.067	3.085GlyAsn: 3.085 ± 0.073	1.595GlyPro: 1.595 ± 0.045	2.015GlyGln: 2.015 ± 0.054	4.436GlyArg: 4.436 ± 0.081	4.469GlySer: 4.469 ± 0.087	4.816GlyThr: 4.816 ± 0.092	5.427GlyVal: 5.427 ± 0.086	0.74GlyTrp: 0.74 ± 0.043	3.17GlyTyr: 3.17 ± 0.06	0.0GlyXaa: 0.0 ± 0.0
His	1.185HisAla: 1.185 ± 0.043	0.307HisCys: 0.307 ± 0.02	0.945HisAsp: 0.945 ± 0.034	1.086HisGlu: 1.086 ± 0.042	0.705HisPhe: 0.705 ± 0.029	1.435HisGly: 1.435 ± 0.046	0.389HisHis: 0.389 ± 0.033	1.315HisIle: 1.315 ± 0.046	0.824HisLys: 0.824 ± 0.036	1.387HisLeu: 1.387 ± 0.045	0.497HisMet: 0.497 ± 0.026	0.588HisAsn: 0.588 ± 0.03	0.929HisPro: 0.929 ± 0.036	0.472HisGln: 0.472 ± 0.028	1.065HisArg: 1.065 ± 0.039	0.95HisSer: 0.95 ± 0.033	0.897HisThr: 0.897 ± 0.034	1.152HisVal: 1.152 ± 0.04	0.175HisTrp: 0.175 ± 0.017	0.788HisTyr: 0.788 ± 0.033	0.0HisXaa: 0.0 ± 0.0
Ile	5.86IleAla: 5.86 ± 0.088	1.28IleCys: 1.28 ± 0.042	4.411IleAsp: 4.411 ± 0.079	4.343IleGlu: 4.343 ± 0.084	2.638IlePhe: 2.638 ± 0.066	5.045IleGly: 5.045 ± 0.086	1.18IleHis: 1.18 ± 0.036	4.458IleIle: 4.458 ± 0.085	2.874IleLys: 2.874 ± 0.073	6.12IleLeu: 6.12 ± 0.117	1.871IleMet: 1.871 ± 0.056	2.459IleAsn: 2.459 ± 0.069	3.012IlePro: 3.012 ± 0.06	1.832IleGln: 1.832 ± 0.045	5.033IleArg: 5.033 ± 0.093	4.406IleSer: 4.406 ± 0.082	4.106IleThr: 4.106 ± 0.082	4.787IleVal: 4.787 ± 0.092	0.541IleTrp: 0.541 ± 0.024	2.289IleTyr: 2.289 ± 0.054	0.0IleXaa: 0.0 ± 0.0
Lys	5.108LysAla: 5.108 ± 0.124	0.617LysCys: 0.617 ± 0.03	3.77LysAsp: 3.77 ± 0.085	5.078LysGlu: 5.078 ± 0.11	1.703LysPhe: 1.703 ± 0.046	3.974LysGly: 3.974 ± 0.081	0.867LysHis: 0.867 ± 0.035	3.959LysIle: 3.959 ± 0.08	5.286LysLys: 5.286 ± 0.115	4.739LysLeu: 4.739 ± 0.087	1.883LysMet: 1.883 ± 0.048	2.79LysAsn: 2.79 ± 0.058	1.952LysPro: 1.952 ± 0.05	1.845LysGln: 1.845 ± 0.053	3.043LysArg: 3.043 ± 0.059	3.322LysSer: 3.322 ± 0.075	3.638LysThr: 3.638 ± 0.072	3.757LysVal: 3.757 ± 0.08	0.579LysTrp: 0.579 ± 0.029	2.655LysTyr: 2.655 ± 0.064	0.0LysXaa: 0.0 ± 0.0
Leu	7.025LeuAla: 7.025 ± 0.108	1.415LeuCys: 1.415 ± 0.046	4.849LeuAsp: 4.849 ± 0.086	5.675LeuGlu: 5.675 ± 0.103	3.407LeuPhe: 3.407 ± 0.077	5.7LeuGly: 5.7 ± 0.088	1.443LeuHis: 1.443 ± 0.047	5.839LeuIle: 5.839 ± 0.093	5.476LeuLys: 5.476 ± 0.089	7.561LeuLeu: 7.561 ± 0.129	2.606LeuMet: 2.606 ± 0.059	3.38LeuAsn: 3.38 ± 0.063	3.494LeuPro: 3.494 ± 0.064	2.444LeuGln: 2.444 ± 0.055	4.937LeuArg: 4.937 ± 0.101	5.927LeuSer: 5.927 ± 0.097	5.151LeuThr: 5.151 ± 0.084	4.972LeuVal: 4.972 ± 0.088	0.682LeuTrp: 0.682 ± 0.031	3.041LeuTyr: 3.041 ± 0.066	0.0LeuXaa: 0.0 ± 0.0
Met	2.508MetAla: 2.508 ± 0.059	0.339MetCys: 0.339 ± 0.021	1.855MetAsp: 1.855 ± 0.047	2.284MetGlu: 2.284 ± 0.054	1.007MetPhe: 1.007 ± 0.039	2.104MetGly: 2.104 ± 0.054	0.463MetHis: 0.463 ± 0.023	2.026MetIle: 2.026 ± 0.055	2.478MetLys: 2.478 ± 0.047	2.532MetLeu: 2.532 ± 0.059	0.94MetMet: 0.94 ± 0.035	1.607MetAsn: 1.607 ± 0.049	1.174MetPro: 1.174 ± 0.04	0.86MetGln: 0.86 ± 0.032	1.601MetArg: 1.601 ± 0.047	1.817MetSer: 1.817 ± 0.049	1.938MetThr: 1.938 ± 0.05	1.708MetVal: 1.708 ± 0.046	0.201MetTrp: 0.201 ± 0.015	0.86MetTyr: 0.86 ± 0.03	0.0MetXaa: 0.0 ± 0.0
Asn	2.932AsnAla: 2.932 ± 0.056	0.591AsnCys: 0.591 ± 0.028	2.049AsnAsp: 2.049 ± 0.055	2.346AsnGlu: 2.346 ± 0.065	1.426AsnPhe: 1.426 ± 0.046	3.35AsnGly: 3.35 ± 0.075	0.686AsnHis: 0.686 ± 0.032	2.915AsnIle: 2.915 ± 0.059	2.124AsnLys: 2.124 ± 0.054	3.296AsnLeu: 3.296 ± 0.061	1.11AsnMet: 1.11 ± 0.036	1.37AsnAsn: 1.37 ± 0.049	1.866AsnPro: 1.866 ± 0.058	1.002AsnGln: 1.002 ± 0.037	2.454AsnArg: 2.454 ± 0.059	2.085AsnSer: 2.085 ± 0.045	2.131AsnThr: 2.131 ± 0.059	2.644AsnVal: 2.644 ± 0.06	0.369AsnTrp: 0.369 ± 0.022	1.617AsnTyr: 1.617 ± 0.049	0.0AsnXaa: 0.0 ± 0.0
Pro	3.228ProAla: 3.228 ± 0.067	0.487ProCys: 0.487 ± 0.024	2.645ProAsp: 2.645 ± 0.062	4.012ProGlu: 4.012 ± 0.08	1.445ProPhe: 1.445 ± 0.043	3.03ProGly: 3.03 ± 0.055	0.612ProHis: 0.612 ± 0.027	1.86ProIle: 1.86 ± 0.055	1.772ProLys: 1.772 ± 0.044	2.799ProLeu: 2.799 ± 0.064	0.917ProMet: 0.917 ± 0.04	1.048ProAsn: 1.048 ± 0.037	0.994ProPro: 0.994 ± 0.035	1.072ProGln: 1.072 ± 0.05	1.543ProArg: 1.543 ± 0.044	1.933ProSer: 1.933 ± 0.062	1.579ProThr: 1.579 ± 0.047	3.29ProVal: 3.29 ± 0.067	0.33ProTrp: 0.33 ± 0.019	1.392ProTyr: 1.392 ± 0.041	0.0ProXaa: 0.0 ± 0.0
Gln	2.368GlnAla: 2.368 ± 0.066	0.336GlnCys: 0.336 ± 0.022	1.383GlnAsp: 1.383 ± 0.042	2.029GlnGlu: 2.029 ± 0.055	1.007GlnPhe: 1.007 ± 0.038	1.802GlnGly: 1.802 ± 0.049	0.474GlnHis: 0.474 ± 0.026	2.16GlnIle: 2.16 ± 0.059	2.228GlnLys: 2.228 ± 0.059	2.448GlnLeu: 2.448 ± 0.057	1.026GlnMet: 1.026 ± 0.038	1.247GlnAsn: 1.247 ± 0.037	0.896GlnPro: 0.896 ± 0.051	1.055GlnGln: 1.055 ± 0.056	1.586GlnArg: 1.586 ± 0.043	1.535GlnSer: 1.535 ± 0.042	1.545GlnThr: 1.545 ± 0.05	1.715GlnVal: 1.715 ± 0.05	0.239GlnTrp: 0.239 ± 0.017	1.182GlnTyr: 1.182 ± 0.042	0.0GlnXaa: 0.0 ± 0.0
Arg	3.972ArgAla: 3.972 ± 0.071	0.807ArgCys: 0.807 ± 0.034	3.404ArgAsp: 3.404 ± 0.071	5.209ArgGlu: 5.209 ± 0.094	2.246ArgPhe: 2.246 ± 0.064	3.781ArgGly: 3.781 ± 0.086	1.026ArgHis: 1.026 ± 0.041	4.504ArgIle: 4.504 ± 0.081	4.173ArgLys: 4.173 ± 0.089	5.058ArgLeu: 5.058 ± 0.097	1.91ArgMet: 1.91 ± 0.052	2.507ArgAsn: 2.507 ± 0.061	1.922ArgPro: 1.922 ± 0.049	2.137ArgGln: 2.137 ± 0.064	4.375ArgArg: 4.375 ± 0.101	3.092ArgSer: 3.092 ± 0.065	3.044ArgThr: 3.044 ± 0.063	3.521ArgVal: 3.521 ± 0.072	0.529ArgTrp: 0.529 ± 0.025	2.443ArgTyr: 2.443 ± 0.058	0.0ArgXaa: 0.0 ± 0.0
Ser	4.902SerAla: 4.902 ± 0.091	0.819SerCys: 0.819 ± 0.032	3.674SerAsp: 3.674 ± 0.072	3.787SerGlu: 3.787 ± 0.066	2.379SerPhe: 2.379 ± 0.064	5.921SerGly: 5.921 ± 0.109	0.972SerHis: 0.972 ± 0.037	3.676SerIle: 3.676 ± 0.068	2.752SerLys: 2.752 ± 0.066	4.812SerLeu: 4.812 ± 0.084	1.714SerMet: 1.714 ± 0.047	1.825SerAsn: 1.825 ± 0.056	2.024SerPro: 2.024 ± 0.047	1.498SerGln: 1.498 ± 0.048	3.856SerArg: 3.856 ± 0.088	3.677SerSer: 3.677 ± 0.096	2.896SerThr: 2.896 ± 0.069	4.505SerVal: 4.505 ± 0.092	0.58SerTrp: 0.58 ± 0.025	2.046SerTyr: 2.046 ± 0.053	0.0SerXaa: 0.0 ± 0.0
Thr	5.036ThrAla: 5.036 ± 0.108	0.726ThrCys: 0.726 ± 0.029	3.495ThrAsp: 3.495 ± 0.067	3.843ThrGlu: 3.843 ± 0.074	2.056ThrPhe: 2.056 ± 0.06	5.326ThrGly: 5.326 ± 0.099	0.872ThrHis: 0.872 ± 0.034	3.461ThrIle: 3.461 ± 0.071	2.856ThrLys: 2.856 ± 0.076	4.751ThrLeu: 4.751 ± 0.093	1.46ThrMet: 1.46 ± 0.043	1.822ThrAsn: 1.822 ± 0.061	2.45ThrPro: 2.45 ± 0.057	1.381ThrGln: 1.381 ± 0.045	2.603ThrArg: 2.603 ± 0.063	2.925ThrSer: 2.925 ± 0.063	2.785ThrThr: 2.785 ± 0.069	4.926ThrVal: 4.926 ± 0.11	0.505ThrTrp: 0.505 ± 0.029	1.894ThrTyr: 1.894 ± 0.068	0.0ThrXaa: 0.0 ± 0.0
Val	5.072ValAla: 5.072 ± 0.078	1.238ValCys: 1.238 ± 0.041	3.835ValAsp: 3.835 ± 0.076	4.215ValGlu: 4.215 ± 0.091	2.884ValPhe: 2.884 ± 0.071	4.265ValGly: 4.265 ± 0.082	1.129ValHis: 1.129 ± 0.04	5.362ValIle: 5.362 ± 0.102	4.047ValLys: 4.047 ± 0.093	6.16ValLeu: 6.16 ± 0.099	2.158ValMet: 2.158 ± 0.058	2.766ValAsn: 2.766 ± 0.058	2.813ValPro: 2.813 ± 0.058	1.657ValGln: 1.657 ± 0.054	4.279ValArg: 4.279 ± 0.091	4.695ValSer: 4.695 ± 0.087	4.524ValThr: 4.524 ± 0.131	4.586ValVal: 4.586 ± 0.101	0.619ValTrp: 0.619 ± 0.032	2.508ValTyr: 2.508 ± 0.057	0.0ValXaa: 0.0 ± 0.0
Trp	0.575TrpAla: 0.575 ± 0.029	0.155TrpCys: 0.155 ± 0.014	0.516TrpAsp: 0.516 ± 0.027	0.568TrpGlu: 0.568 ± 0.031	0.388TrpPhe: 0.388 ± 0.023	0.614TrpGly: 0.614 ± 0.029	0.169TrpHis: 0.169 ± 0.016	0.625TrpIle: 0.625 ± 0.03	0.643TrpLys: 0.643 ± 0.031	0.802TrpLeu: 0.802 ± 0.032	0.279TrpMet: 0.279 ± 0.021	0.485TrpAsn: 0.485 ± 0.029	0.268TrpPro: 0.268 ± 0.02	0.33TrpGln: 0.33 ± 0.02	0.452TrpArg: 0.452 ± 0.026	0.534TrpSer: 0.534 ± 0.035	0.462TrpThr: 0.462 ± 0.028	0.501TrpVal: 0.501 ± 0.029	0.092TrpTrp: 0.092 ± 0.012	0.371TrpTyr: 0.371 ± 0.024	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.874TyrAla: 2.874 ± 0.07	0.613TyrCys: 0.613 ± 0.027	2.653TyrAsp: 2.653 ± 0.052	2.604TyrGlu: 2.604 ± 0.065	1.569TyrPhe: 1.569 ± 0.046	3.054TyrGly: 3.054 ± 0.068	0.72TyrHis: 0.72 ± 0.028	2.362TyrIle: 2.362 ± 0.057	2.087TyrLys: 2.087 ± 0.06	3.111TyrLeu: 3.111 ± 0.067	1.033TyrMet: 1.033 ± 0.037	1.533TyrAsn: 1.533 ± 0.052	1.368TyrPro: 1.368 ± 0.045	1.113TyrGln: 1.113 ± 0.041	2.504TyrArg: 2.504 ± 0.06	2.294TyrSer: 2.294 ± 0.068	2.205TyrThr: 2.205 ± 0.068	2.336TyrVal: 2.336 ± 0.052	0.366TyrTrp: 0.366 ± 0.026	1.652TyrTyr: 1.652 ± 0.051	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2432 proteins (794604 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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