Amino acid dipepetide frequency for Gordonia hirsuta DSM 44140 = NBRC 16056

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
21.533AlaAla: 21.533 ± 0.236
0.849AlaCys: 0.849 ± 0.028
9.057AlaAsp: 9.057 ± 0.107
7.994AlaGlu: 7.994 ± 0.112
3.359AlaPhe: 3.359 ± 0.059
12.864AlaGly: 12.864 ± 0.135
2.401AlaHis: 2.401 ± 0.057
5.16AlaIle: 5.16 ± 0.08
2.784AlaLys: 2.784 ± 0.063
13.167AlaLeu: 13.167 ± 0.128
2.776AlaMet: 2.776 ± 0.051
2.173AlaAsn: 2.173 ± 0.053
6.799AlaPro: 6.799 ± 0.085
4.826AlaGln: 4.826 ± 0.061
8.804AlaArg: 8.804 ± 0.11
5.355AlaSer: 5.355 ± 0.082
7.218AlaThr: 7.218 ± 0.093
11.817AlaVal: 11.817 ± 0.127
1.553AlaTrp: 1.553 ± 0.039
2.325AlaTyr: 2.325 ± 0.044
0.0AlaXaa: 0.0 ± 0.0
Cys
0.946CysAla: 0.946 ± 0.032
0.059CysCys: 0.059 ± 0.007
0.431CysAsp: 0.431 ± 0.022
0.36CysGlu: 0.36 ± 0.02
0.205CysPhe: 0.205 ± 0.012
0.833CysGly: 0.833 ± 0.032
0.144CysHis: 0.144 ± 0.011
0.231CysIle: 0.231 ± 0.016
0.114CysLys: 0.114 ± 0.011
0.557CysLeu: 0.557 ± 0.023
0.12CysMet: 0.12 ± 0.012
0.134CysAsn: 0.134 ± 0.012
0.41CysPro: 0.41 ± 0.021
0.166CysGln: 0.166 ± 0.012
0.496CysArg: 0.496 ± 0.026
0.388CysSer: 0.388 ± 0.02
0.464CysThr: 0.464 ± 0.02
0.532CysVal: 0.532 ± 0.024
0.12CysTrp: 0.12 ± 0.013
0.148CysTyr: 0.148 ± 0.012
0.0CysXaa: 0.0 ± 0.0
Asp
7.43AspAla: 7.43 ± 0.089
0.392AspCys: 0.392 ± 0.018
4.742AspAsp: 4.742 ± 0.074
4.162AspGlu: 4.162 ± 0.069
1.93AspPhe: 1.93 ± 0.042
6.526AspGly: 6.526 ± 0.091
1.365AspHis: 1.365 ± 0.036
2.24AspIle: 2.24 ± 0.055
1.302AspLys: 1.302 ± 0.04
6.709AspLeu: 6.709 ± 0.098
1.0AspMet: 1.0 ± 0.032
1.025AspAsn: 1.025 ± 0.034
4.859AspPro: 4.859 ± 0.076
2.013AspGln: 2.013 ± 0.046
5.074AspArg: 5.074 ± 0.077
2.814AspSer: 2.814 ± 0.053
3.102AspThr: 3.102 ± 0.065
4.949AspVal: 4.949 ± 0.082
0.961AspTrp: 0.961 ± 0.03
1.479AspTyr: 1.479 ± 0.041
0.0AspXaa: 0.0 ± 0.0
Glu
6.385GluAla: 6.385 ± 0.096
0.329GluCys: 0.329 ± 0.015
2.441GluAsp: 2.441 ± 0.06
2.675GluGlu: 2.675 ± 0.056
1.871GluPhe: 1.871 ± 0.043
3.304GluGly: 3.304 ± 0.061
1.429GluHis: 1.429 ± 0.036
2.678GluIle: 2.678 ± 0.057
1.386GluLys: 1.386 ± 0.052
6.818GluLeu: 6.818 ± 0.102
1.118GluMet: 1.118 ± 0.039
1.226GluAsn: 1.226 ± 0.035
3.022GluPro: 3.022 ± 0.06
2.582GluGln: 2.582 ± 0.056
4.368GluArg: 4.368 ± 0.073
2.84GluSer: 2.84 ± 0.067
2.738GluThr: 2.738 ± 0.05
4.686GluVal: 4.686 ± 0.081
0.684GluTrp: 0.684 ± 0.024
1.188GluTyr: 1.188 ± 0.036
0.0GluXaa: 0.0 ± 0.0
Phe
4.135PheAla: 4.135 ± 0.064
0.264PheCys: 0.264 ± 0.014
2.348PheAsp: 2.348 ± 0.064
1.44PheGlu: 1.44 ± 0.044
0.959PhePhe: 0.959 ± 0.031
3.471PheGly: 3.471 ± 0.058
0.545PheHis: 0.545 ± 0.024
1.021PheIle: 1.021 ± 0.035
0.457PheLys: 0.457 ± 0.02
2.637PheLeu: 2.637 ± 0.057
0.429PheMet: 0.429 ± 0.02
0.675PheAsn: 0.675 ± 0.024
1.384PhePro: 1.384 ± 0.038
0.669PheGln: 0.669 ± 0.028
1.576PheArg: 1.576 ± 0.04
1.622PheSer: 1.622 ± 0.043
2.143PheThr: 2.143 ± 0.051
2.414PheVal: 2.414 ± 0.051
0.41PheTrp: 0.41 ± 0.022
0.618PheTyr: 0.618 ± 0.024
0.0PheXaa: 0.0 ± 0.0
Gly
10.778GlyAla: 10.778 ± 0.114
0.705GlyCys: 0.705 ± 0.026
5.385GlyAsp: 5.385 ± 0.089
4.85GlyGlu: 4.85 ± 0.086
3.061GlyPhe: 3.061 ± 0.053
8.046GlyGly: 8.046 ± 0.117
1.901GlyHis: 1.901 ± 0.042
4.22GlyIle: 4.22 ± 0.07
2.372GlyLys: 2.372 ± 0.054
9.022GlyLeu: 9.022 ± 0.115
2.165GlyMet: 2.165 ± 0.048
1.768GlyAsn: 1.768 ± 0.041
4.921GlyPro: 4.921 ± 0.081
3.034GlyGln: 3.034 ± 0.064
6.824GlyArg: 6.824 ± 0.083
5.077GlySer: 5.077 ± 0.062
5.673GlyThr: 5.673 ± 0.083
7.495GlyVal: 7.495 ± 0.085
1.422GlyTrp: 1.422 ± 0.039
2.419GlyTyr: 2.419 ± 0.049
0.0GlyXaa: 0.0 ± 0.0
His
2.106HisAla: 2.106 ± 0.048
0.178HisCys: 0.178 ± 0.012
1.301HisAsp: 1.301 ± 0.033
0.932HisGlu: 0.932 ± 0.036
0.587HisPhe: 0.587 ± 0.024
1.926HisGly: 1.926 ± 0.046
0.556HisHis: 0.556 ± 0.024
0.736HisIle: 0.736 ± 0.026
0.349HisLys: 0.349 ± 0.02
2.054HisLeu: 2.054 ± 0.045
0.312HisMet: 0.312 ± 0.015
0.394HisAsn: 0.394 ± 0.021
1.517HisPro: 1.517 ± 0.04
0.611HisGln: 0.611 ± 0.025
1.852HisArg: 1.852 ± 0.051
1.006HisSer: 1.006 ± 0.031
1.154HisThr: 1.154 ± 0.034
1.377HisVal: 1.377 ± 0.036
0.338HisTrp: 0.338 ± 0.018
0.442HisTyr: 0.442 ± 0.019
0.0HisXaa: 0.0 ± 0.0
Ile
6.728IleAla: 6.728 ± 0.077
0.38IleCys: 0.38 ± 0.02
3.668IleAsp: 3.668 ± 0.06
2.571IleGlu: 2.571 ± 0.05
1.133IlePhe: 1.133 ± 0.037
4.824IleGly: 4.824 ± 0.081
0.716IleHis: 0.716 ± 0.03
1.563IleIle: 1.563 ± 0.043
0.831IleLys: 0.831 ± 0.031
3.505IleLeu: 3.505 ± 0.067
0.64IleMet: 0.64 ± 0.028
1.044IleAsn: 1.044 ± 0.033
2.383IlePro: 2.383 ± 0.049
0.875IleGln: 0.875 ± 0.033
2.45IleArg: 2.45 ± 0.052
2.306IleSer: 2.306 ± 0.053
2.803IleThr: 2.803 ± 0.051
3.954IleVal: 3.954 ± 0.07
0.458IleTrp: 0.458 ± 0.022
0.786IleTyr: 0.786 ± 0.029
0.0IleXaa: 0.0 ± 0.0
Lys
2.51LysAla: 2.51 ± 0.063
0.085LysCys: 0.085 ± 0.01
1.066LysAsp: 1.066 ± 0.036
0.911LysGlu: 0.911 ± 0.036
0.561LysPhe: 0.561 ± 0.024
1.569LysGly: 1.569 ± 0.043
0.429LysHis: 0.429 ± 0.021
1.125LysIle: 1.125 ± 0.038
0.878LysLys: 0.878 ± 0.043
2.019LysLeu: 2.019 ± 0.043
0.522LysMet: 0.522 ± 0.024
0.623LysAsn: 0.623 ± 0.023
1.316LysPro: 1.316 ± 0.055
0.693LysGln: 0.693 ± 0.025
1.439LysArg: 1.439 ± 0.035
1.17LysSer: 1.17 ± 0.037
1.443LysThr: 1.443 ± 0.046
1.944LysVal: 1.944 ± 0.054
0.263LysTrp: 0.263 ± 0.015
0.5LysTyr: 0.5 ± 0.025
0.0LysXaa: 0.0 ± 0.0
Leu
14.65LeuAla: 14.65 ± 0.152
0.645LeuCys: 0.645 ± 0.026
6.724LeuAsp: 6.724 ± 0.092
4.542LeuGlu: 4.542 ± 0.086
2.603LeuPhe: 2.603 ± 0.052
8.942LeuGly: 8.942 ± 0.099
1.915LeuHis: 1.915 ± 0.042
4.786LeuIle: 4.786 ± 0.088
1.745LeuLys: 1.745 ± 0.046
9.984LeuLeu: 9.984 ± 0.127
1.789LeuMet: 1.789 ± 0.046
2.038LeuAsn: 2.038 ± 0.045
5.919LeuPro: 5.919 ± 0.087
2.475LeuGln: 2.475 ± 0.043
7.225LeuArg: 7.225 ± 0.097
5.619LeuSer: 5.619 ± 0.078
6.936LeuThr: 6.936 ± 0.078
8.581LeuVal: 8.581 ± 0.116
1.232LeuTrp: 1.232 ± 0.037
1.687LeuTyr: 1.687 ± 0.04
0.0LeuXaa: 0.0 ± 0.0
Met
2.467MetAla: 2.467 ± 0.053
0.154MetCys: 0.154 ± 0.011
0.904MetAsp: 0.904 ± 0.029
0.757MetGlu: 0.757 ± 0.024
0.584MetPhe: 0.584 ± 0.024
1.535MetGly: 1.535 ± 0.041
0.355MetHis: 0.355 ± 0.018
1.053MetIle: 1.053 ± 0.034
0.472MetLys: 0.472 ± 0.021
2.061MetLeu: 2.061 ± 0.043
0.448MetMet: 0.448 ± 0.025
0.53MetAsn: 0.53 ± 0.021
1.147MetPro: 1.147 ± 0.03
0.466MetGln: 0.466 ± 0.023
1.373MetArg: 1.373 ± 0.042
1.605MetSer: 1.605 ± 0.043
1.895MetThr: 1.895 ± 0.042
1.692MetVal: 1.692 ± 0.048
0.246MetTrp: 0.246 ± 0.015
0.355MetTyr: 0.355 ± 0.02
0.0MetXaa: 0.0 ± 0.0
Asn
2.34AsnAla: 2.34 ± 0.05
0.143AsnCys: 0.143 ± 0.012
1.223AsnAsp: 1.223 ± 0.032
0.966AsnGlu: 0.966 ± 0.032
0.558AsnPhe: 0.558 ± 0.026
1.791AsnGly: 1.791 ± 0.051
0.4AsnHis: 0.4 ± 0.019
0.917AsnIle: 0.917 ± 0.03
0.514AsnLys: 0.514 ± 0.026
2.073AsnLeu: 2.073 ± 0.05
0.387AsnMet: 0.387 ± 0.019
0.528AsnAsn: 0.528 ± 0.023
1.557AsnPro: 1.557 ± 0.045
0.68AsnGln: 0.68 ± 0.025
1.494AsnArg: 1.494 ± 0.037
1.024AsnSer: 1.024 ± 0.034
1.247AsnThr: 1.247 ± 0.037
1.606AsnVal: 1.606 ± 0.036
0.307AsnTrp: 0.307 ± 0.018
0.48AsnTyr: 0.48 ± 0.022
0.0AsnXaa: 0.0 ± 0.0
Pro
8.129ProAla: 8.129 ± 0.134
0.249ProCys: 0.249 ± 0.018
4.395ProAsp: 4.395 ± 0.07
4.131ProGlu: 4.131 ± 0.081
1.543ProPhe: 1.543 ± 0.04
6.098ProGly: 6.098 ± 0.093
1.075ProHis: 1.075 ± 0.036
2.297ProIle: 2.297 ± 0.056
1.208ProLys: 1.208 ± 0.041
4.838ProLeu: 4.838 ± 0.079
1.242ProMet: 1.242 ± 0.036
1.15ProAsn: 1.15 ± 0.04
3.182ProPro: 3.182 ± 0.085
2.049ProGln: 2.049 ± 0.053
3.447ProArg: 3.447 ± 0.061
2.929ProSer: 2.929 ± 0.059
3.243ProThr: 3.243 ± 0.061
5.317ProVal: 5.317 ± 0.077
0.776ProTrp: 0.776 ± 0.028
1.13ProTyr: 1.13 ± 0.037
0.0ProXaa: 0.0 ± 0.0
Gln
3.966GlnAla: 3.966 ± 0.061
0.195GlnCys: 0.195 ± 0.013
1.261GlnAsp: 1.261 ± 0.034
1.306GlnGlu: 1.306 ± 0.037
0.888GlnPhe: 0.888 ± 0.028
1.987GlnGly: 1.987 ± 0.051
0.589GlnHis: 0.589 ± 0.022
1.908GlnIle: 1.908 ± 0.049
0.649GlnLys: 0.649 ± 0.026
3.541GlnLeu: 3.541 ± 0.058
0.725GlnMet: 0.725 ± 0.025
0.656GlnAsn: 0.656 ± 0.03
1.686GlnPro: 1.686 ± 0.046
1.407GlnGln: 1.407 ± 0.046
2.656GlnArg: 2.656 ± 0.045
1.512GlnSer: 1.512 ± 0.041
2.034GlnThr: 2.034 ± 0.045
3.234GlnVal: 3.234 ± 0.053
0.575GlnTrp: 0.575 ± 0.024
0.683GlnTyr: 0.683 ± 0.031
0.0GlnXaa: 0.0 ± 0.0
Arg
8.192ArgAla: 8.192 ± 0.108
0.494ArgCys: 0.494 ± 0.024
4.054ArgAsp: 4.054 ± 0.069
4.107ArgGlu: 4.107 ± 0.067
2.252ArgPhe: 2.252 ± 0.037
5.327ArgGly: 5.327 ± 0.071
1.567ArgHis: 1.567 ± 0.036
3.471ArgIle: 3.471 ± 0.059
1.612ArgLys: 1.612 ± 0.042
7.526ArgLeu: 7.526 ± 0.092
1.788ArgMet: 1.788 ± 0.038
1.511ArgAsn: 1.511 ± 0.041
4.204ArgPro: 4.204 ± 0.071
2.279ArgGln: 2.279 ± 0.052
6.801ArgArg: 6.801 ± 0.119
4.01ArgSer: 4.01 ± 0.069
4.53ArgThr: 4.53 ± 0.061
5.414ArgVal: 5.414 ± 0.07
1.243ArgTrp: 1.243 ± 0.036
1.848ArgTyr: 1.848 ± 0.042
0.0ArgXaa: 0.0 ± 0.0
Ser
6.951SerAla: 6.951 ± 0.086
0.35SerCys: 0.35 ± 0.021
3.078SerAsp: 3.078 ± 0.059
2.482SerGlu: 2.482 ± 0.048
1.616SerPhe: 1.616 ± 0.036
5.677SerGly: 5.677 ± 0.082
0.899SerHis: 0.899 ± 0.028
2.154SerIle: 2.154 ± 0.051
1.056SerLys: 1.056 ± 0.04
4.701SerLeu: 4.701 ± 0.067
1.248SerMet: 1.248 ± 0.031
0.921SerAsn: 0.921 ± 0.035
3.223SerPro: 3.223 ± 0.058
1.467SerGln: 1.467 ± 0.039
3.561SerArg: 3.561 ± 0.06
3.209SerSer: 3.209 ± 0.066
3.349SerThr: 3.349 ± 0.062
4.304SerVal: 4.304 ± 0.086
0.805SerTrp: 0.805 ± 0.029
1.102SerTyr: 1.102 ± 0.037
0.0SerXaa: 0.0 ± 0.0
Thr
8.502ThrAla: 8.502 ± 0.113
0.398ThrCys: 0.398 ± 0.021
3.924ThrAsp: 3.924 ± 0.059
3.543ThrGlu: 3.543 ± 0.062
1.662ThrPhe: 1.662 ± 0.039
6.625ThrGly: 6.625 ± 0.084
1.061ThrHis: 1.061 ± 0.029
2.394ThrIle: 2.394 ± 0.056
1.151ThrLys: 1.151 ± 0.04
5.567ThrLeu: 5.567 ± 0.076
1.182ThrMet: 1.182 ± 0.033
1.076ThrAsn: 1.076 ± 0.034
3.934ThrPro: 3.934 ± 0.061
1.625ThrGln: 1.625 ± 0.035
3.753ThrArg: 3.753 ± 0.073
3.062ThrSer: 3.062 ± 0.059
3.656ThrThr: 3.656 ± 0.076
6.367ThrVal: 6.367 ± 0.083
0.778ThrTrp: 0.778 ± 0.032
1.256ThrTyr: 1.256 ± 0.032
0.0ThrXaa: 0.0 ± 0.0
Val
11.228ValAla: 11.228 ± 0.134
0.655ValCys: 0.655 ± 0.024
5.981ValAsp: 5.981 ± 0.089
4.47ValGlu: 4.47 ± 0.108
2.542ValPhe: 2.542 ± 0.048
6.842ValGly: 6.842 ± 0.089
1.741ValHis: 1.741 ± 0.045
4.301ValIle: 4.301 ± 0.061
1.543ValLys: 1.543 ± 0.042
9.217ValLeu: 9.217 ± 0.129
1.586ValMet: 1.586 ± 0.041
1.903ValAsn: 1.903 ± 0.049
5.005ValPro: 5.005 ± 0.081
2.316ValGln: 2.316 ± 0.05
5.931ValArg: 5.931 ± 0.076
4.646ValSer: 4.646 ± 0.069
5.778ValThr: 5.778 ± 0.078
8.587ValVal: 8.587 ± 0.128
0.972ValTrp: 0.972 ± 0.03
1.612ValTyr: 1.612 ± 0.04
0.0ValXaa: 0.0 ± 0.0
Trp
1.474TrpAla: 1.474 ± 0.04
0.134TrpCys: 0.134 ± 0.011
0.693TrpAsp: 0.693 ± 0.026
0.589TrpGlu: 0.589 ± 0.026
0.534TrpPhe: 0.534 ± 0.022
0.94TrpGly: 0.94 ± 0.03
0.293TrpHis: 0.293 ± 0.015
0.678TrpIle: 0.678 ± 0.028
0.293TrpLys: 0.293 ± 0.017
1.595TrpLeu: 1.595 ± 0.05
0.337TrpMet: 0.337 ± 0.018
0.389TrpAsn: 0.389 ± 0.02
0.741TrpPro: 0.741 ± 0.023
0.581TrpGln: 0.581 ± 0.025
1.174TrpArg: 1.174 ± 0.036
0.817TrpSer: 0.817 ± 0.027
0.859TrpThr: 0.859 ± 0.033
1.041TrpVal: 1.041 ± 0.031
0.347TrpTrp: 0.347 ± 0.022
0.32TrpTyr: 0.32 ± 0.018
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.361TyrAla: 2.361 ± 0.052
0.201TyrCys: 0.201 ± 0.017
1.397TyrAsp: 1.397 ± 0.038
0.976TyrGlu: 0.976 ± 0.031
0.764TyrPhe: 0.764 ± 0.025
2.013TyrGly: 2.013 ± 0.048
0.348TyrHis: 0.348 ± 0.017
0.687TyrIle: 0.687 ± 0.024
0.348TyrLys: 0.348 ± 0.019
2.449TyrLeu: 2.449 ± 0.052
0.285TyrMet: 0.285 ± 0.019
0.472TyrAsn: 0.472 ± 0.025
1.218TyrPro: 1.218 ± 0.036
0.649TyrGln: 0.649 ± 0.025
1.935TyrArg: 1.935 ± 0.047
1.143TyrSer: 1.143 ± 0.036
1.247TyrThr: 1.247 ± 0.037
1.545TyrVal: 1.545 ± 0.042
0.34TyrTrp: 0.34 ± 0.017
0.496TyrTyr: 0.496 ± 0.022
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3215 proteins (1071027 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski