Amino acid dipepetide frequency for Aliidiomarina sanyensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.646AlaAla: 9.646 ± 0.133	0.989AlaCys: 0.989 ± 0.032	5.4AlaAsp: 5.4 ± 0.102	6.803AlaGlu: 6.803 ± 0.104	3.779AlaPhe: 3.779 ± 0.078	7.078AlaGly: 7.078 ± 0.114	2.311AlaHis: 2.311 ± 0.054	5.741AlaIle: 5.741 ± 0.103	3.418AlaLys: 3.418 ± 0.079	11.535AlaLeu: 11.535 ± 0.13	2.689AlaMet: 2.689 ± 0.066	3.056AlaAsn: 3.056 ± 0.069	3.715AlaPro: 3.715 ± 0.076	4.712AlaGln: 4.712 ± 0.086	6.165AlaArg: 6.165 ± 0.096	5.21AlaSer: 5.21 ± 0.088	4.703AlaThr: 4.703 ± 0.086	6.74AlaVal: 6.74 ± 0.097	1.345AlaTrp: 1.345 ± 0.046	2.507AlaTyr: 2.507 ± 0.051	0.0AlaXaa: 0.0 ± 0.0
Cys	0.814CysAla: 0.814 ± 0.029	0.106CysCys: 0.106 ± 0.012	0.462CysAsp: 0.462 ± 0.024	0.567CysGlu: 0.567 ± 0.029	0.344CysPhe: 0.344 ± 0.021	0.759CysGly: 0.759 ± 0.033	0.248CysHis: 0.248 ± 0.018	0.448CysIle: 0.448 ± 0.024	0.284CysLys: 0.284 ± 0.021	0.732CysLeu: 0.732 ± 0.037	0.162CysMet: 0.162 ± 0.015	0.255CysAsn: 0.255 ± 0.018	0.433CysPro: 0.433 ± 0.024	0.36CysGln: 0.36 ± 0.02	0.45CysArg: 0.45 ± 0.025	0.55CysSer: 0.55 ± 0.027	0.425CysThr: 0.425 ± 0.025	0.599CysVal: 0.599 ± 0.029	0.112CysTrp: 0.112 ± 0.011	0.239CysTyr: 0.239 ± 0.02	0.0CysXaa: 0.0 ± 0.0
Asp	5.538AspAla: 5.538 ± 0.079	0.438AspCys: 0.438 ± 0.028	3.33AspAsp: 3.33 ± 0.076	3.801AspGlu: 3.801 ± 0.08	2.603AspPhe: 2.603 ± 0.056	4.118AspGly: 4.118 ± 0.088	1.379AspHis: 1.379 ± 0.04	3.454AspIle: 3.454 ± 0.063	1.826AspLys: 1.826 ± 0.061	5.186AspLeu: 5.186 ± 0.096	1.447AspMet: 1.447 ± 0.046	1.604AspAsn: 1.604 ± 0.042	2.489AspPro: 2.489 ± 0.054	2.05AspGln: 2.05 ± 0.055	3.221AspArg: 3.221 ± 0.075	2.709AspSer: 2.709 ± 0.063	2.648AspThr: 2.648 ± 0.055	4.362AspVal: 4.362 ± 0.076	0.917AspTrp: 0.917 ± 0.038	1.883AspTyr: 1.883 ± 0.046	0.0AspXaa: 0.0 ± 0.0
Glu	6.315GluAla: 6.315 ± 0.094	0.384GluCys: 0.384 ± 0.02	2.98GluAsp: 2.98 ± 0.067	3.68GluGlu: 3.68 ± 0.093	2.534GluPhe: 2.534 ± 0.056	4.035GluGly: 4.035 ± 0.09	1.985GluHis: 1.985 ± 0.059	3.626GluIle: 3.626 ± 0.066	2.72GluLys: 2.72 ± 0.075	7.035GluLeu: 7.035 ± 0.104	1.616GluMet: 1.616 ± 0.049	2.293GluAsn: 2.293 ± 0.056	2.507GluPro: 2.507 ± 0.068	4.023GluGln: 4.023 ± 0.08	5.414GluArg: 5.414 ± 0.092	3.464GluSer: 3.464 ± 0.075	3.371GluThr: 3.371 ± 0.072	4.477GluVal: 4.477 ± 0.08	0.838GluTrp: 0.838 ± 0.031	1.591GluTyr: 1.591 ± 0.048	0.0GluXaa: 0.0 ± 0.0
Phe	4.16PheAla: 4.16 ± 0.081	0.388PheCys: 0.388 ± 0.025	2.52PheAsp: 2.52 ± 0.059	2.492PheGlu: 2.492 ± 0.053	1.713PhePhe: 1.713 ± 0.054	3.32PheGly: 3.32 ± 0.074	0.962PheHis: 0.962 ± 0.033	2.353PheIle: 2.353 ± 0.059	1.262PheLys: 1.262 ± 0.043	3.661PheLeu: 3.661 ± 0.081	0.996PheMet: 0.996 ± 0.027	1.561PheAsn: 1.561 ± 0.049	1.655PhePro: 1.655 ± 0.048	1.404PheGln: 1.404 ± 0.046	2.337PheArg: 2.337 ± 0.053	2.929PheSer: 2.929 ± 0.062	2.397PheThr: 2.397 ± 0.055	3.096PheVal: 3.096 ± 0.067	0.585PheTrp: 0.585 ± 0.03	1.299PheTyr: 1.299 ± 0.044	0.0PheXaa: 0.0 ± 0.0
Gly	6.408GlyAla: 6.408 ± 0.121	0.768GlyCys: 0.768 ± 0.036	3.885GlyAsp: 3.885 ± 0.077	4.544GlyGlu: 4.544 ± 0.087	3.507GlyPhe: 3.507 ± 0.07	5.246GlyGly: 5.246 ± 0.089	1.843GlyHis: 1.843 ± 0.053	4.455GlyIle: 4.455 ± 0.083	3.056GlyLys: 3.056 ± 0.081	7.404GlyLeu: 7.404 ± 0.112	2.175GlyMet: 2.175 ± 0.055	2.266GlyAsn: 2.266 ± 0.065	2.365GlyPro: 2.365 ± 0.058	3.145GlyGln: 3.145 ± 0.073	4.283GlyArg: 4.283 ± 0.078	4.005GlySer: 4.005 ± 0.082	3.829GlyThr: 3.829 ± 0.072	5.739GlyVal: 5.739 ± 0.09	1.06GlyTrp: 1.06 ± 0.037	2.483GlyTyr: 2.483 ± 0.049	0.0GlyXaa: 0.0 ± 0.0
His	2.405HisAla: 2.405 ± 0.059	0.276HisCys: 0.276 ± 0.02	1.382HisAsp: 1.382 ± 0.055	1.58HisGlu: 1.58 ± 0.042	1.133HisPhe: 1.133 ± 0.04	2.064HisGly: 2.064 ± 0.062	0.754HisHis: 0.754 ± 0.036	1.379HisIle: 1.379 ± 0.04	0.757HisLys: 0.757 ± 0.035	2.392HisLeu: 2.392 ± 0.062	0.517HisMet: 0.517 ± 0.022	0.69HisAsn: 0.69 ± 0.03	1.483HisPro: 1.483 ± 0.045	1.192HisGln: 1.192 ± 0.045	1.579HisArg: 1.579 ± 0.05	1.253HisSer: 1.253 ± 0.043	1.153HisThr: 1.153 ± 0.04	1.812HisVal: 1.812 ± 0.051	0.443HisTrp: 0.443 ± 0.023	0.858HisTyr: 0.858 ± 0.038	0.0HisXaa: 0.0 ± 0.0
Ile	6.29IleAla: 6.29 ± 0.105	0.498IleCys: 0.498 ± 0.03	3.583IleAsp: 3.583 ± 0.074	4.187IleGlu: 4.187 ± 0.094	2.114IlePhe: 2.114 ± 0.057	4.558IleGly: 4.558 ± 0.088	1.369IleHis: 1.369 ± 0.044	2.773IleIle: 2.773 ± 0.068	1.756IleLys: 1.756 ± 0.05	5.228IleLeu: 5.228 ± 0.09	1.115IleMet: 1.115 ± 0.041	1.906IleAsn: 1.906 ± 0.053	2.806IlePro: 2.806 ± 0.063	2.485IleGln: 2.485 ± 0.052	3.516IleArg: 3.516 ± 0.06	3.308IleSer: 3.308 ± 0.07	3.083IleThr: 3.083 ± 0.06	3.897IleVal: 3.897 ± 0.079	0.649IleTrp: 0.649 ± 0.032	1.542IleTyr: 1.542 ± 0.044	0.0IleXaa: 0.0 ± 0.0
Lys	3.714LysAla: 3.714 ± 0.084	0.189LysCys: 0.189 ± 0.017	1.805LysAsp: 1.805 ± 0.051	2.165LysGlu: 2.165 ± 0.074	1.129LysPhe: 1.129 ± 0.035	2.275LysGly: 2.275 ± 0.066	0.995LysHis: 0.995 ± 0.037	1.856LysIle: 1.856 ± 0.049	1.975LysLys: 1.975 ± 0.061	3.534LysLeu: 3.534 ± 0.086	0.909LysMet: 0.909 ± 0.034	1.234LysAsn: 1.234 ± 0.04	1.851LysPro: 1.851 ± 0.055	1.802LysGln: 1.802 ± 0.051	2.593LysArg: 2.593 ± 0.065	2.075LysSer: 2.075 ± 0.058	2.03LysThr: 2.03 ± 0.055	2.524LysVal: 2.524 ± 0.072	0.365LysTrp: 0.365 ± 0.022	0.869LysTyr: 0.869 ± 0.036	0.0LysXaa: 0.0 ± 0.0
Leu	10.893LeuAla: 10.893 ± 0.139	0.9LeuCys: 0.9 ± 0.038	5.553LeuAsp: 5.553 ± 0.085	6.561LeuGlu: 6.561 ± 0.104	4.053LeuPhe: 4.053 ± 0.072	7.345LeuGly: 7.345 ± 0.112	2.479LeuHis: 2.479 ± 0.07	5.737LeuIle: 5.737 ± 0.101	3.87LeuLys: 3.87 ± 0.086	10.707LeuLeu: 10.707 ± 0.146	2.566LeuMet: 2.566 ± 0.052	3.824LeuAsn: 3.824 ± 0.068	5.164LeuPro: 5.164 ± 0.084	4.516LeuGln: 4.516 ± 0.072	6.656LeuArg: 6.656 ± 0.091	6.578LeuSer: 6.578 ± 0.1	5.951LeuThr: 5.951 ± 0.09	7.169LeuVal: 7.169 ± 0.115	1.273LeuTrp: 1.273 ± 0.037	2.517LeuTyr: 2.517 ± 0.062	0.0LeuXaa: 0.0 ± 0.0
Met	2.589MetAla: 2.589 ± 0.06	0.157MetCys: 0.157 ± 0.016	1.212MetAsp: 1.212 ± 0.039	1.303MetGlu: 1.303 ± 0.044	0.811MetPhe: 0.811 ± 0.032	1.651MetGly: 1.651 ± 0.05	0.6MetHis: 0.6 ± 0.032	1.304MetIle: 1.304 ± 0.04	1.155MetLys: 1.155 ± 0.037	2.738MetLeu: 2.738 ± 0.064	0.701MetMet: 0.701 ± 0.034	1.017MetAsn: 1.017 ± 0.031	1.276MetPro: 1.276 ± 0.042	1.332MetGln: 1.332 ± 0.041	1.607MetArg: 1.607 ± 0.05	1.708MetSer: 1.708 ± 0.042	1.643MetThr: 1.643 ± 0.044	1.746MetVal: 1.746 ± 0.045	0.248MetTrp: 0.248 ± 0.017	0.561MetTyr: 0.561 ± 0.027	0.0MetXaa: 0.0 ± 0.0
Asn	3.211AsnAla: 3.211 ± 0.062	0.257AsnCys: 0.257 ± 0.018	1.824AsnAsp: 1.824 ± 0.05	2.138AsnGlu: 2.138 ± 0.057	1.307AsnPhe: 1.307 ± 0.048	2.399AsnGly: 2.399 ± 0.06	0.747AsnHis: 0.747 ± 0.033	1.833AsnIle: 1.833 ± 0.056	1.083AsnLys: 1.083 ± 0.044	3.259AsnLeu: 3.259 ± 0.069	0.812AsnMet: 0.812 ± 0.032	1.029AsnAsn: 1.029 ± 0.04	2.193AsnPro: 2.193 ± 0.053	1.613AsnGln: 1.613 ± 0.046	2.183AsnArg: 2.183 ± 0.061	1.595AsnSer: 1.595 ± 0.052	1.867AsnThr: 1.867 ± 0.047	2.247AsnVal: 2.247 ± 0.059	0.525AsnTrp: 0.525 ± 0.029	1.047AsnTyr: 1.047 ± 0.041	0.0AsnXaa: 0.0 ± 0.0
Pro	3.939ProAla: 3.939 ± 0.079	0.317ProCys: 0.317 ± 0.019	2.903ProAsp: 2.903 ± 0.058	3.962ProGlu: 3.962 ± 0.09	1.862ProPhe: 1.862 ± 0.045	3.244ProGly: 3.244 ± 0.066	1.066ProHis: 1.066 ± 0.04	2.431ProIle: 2.431 ± 0.055	1.669ProLys: 1.669 ± 0.051	4.47ProLeu: 4.47 ± 0.08	1.169ProMet: 1.169 ± 0.038	1.561ProAsn: 1.561 ± 0.047	1.603ProPro: 1.603 ± 0.051	1.898ProGln: 1.898 ± 0.048	2.299ProArg: 2.299 ± 0.052	2.516ProSer: 2.516 ± 0.055	2.208ProThr: 2.208 ± 0.051	3.56ProVal: 3.56 ± 0.072	0.683ProTrp: 0.683 ± 0.027	1.216ProTyr: 1.216 ± 0.037	0.0ProXaa: 0.0 ± 0.0
Gln	4.898GlnAla: 4.898 ± 0.082	0.277GlnCys: 0.277 ± 0.021	2.03GlnAsp: 2.03 ± 0.059	2.681GlnGlu: 2.681 ± 0.07	1.798GlnPhe: 1.798 ± 0.052	3.385GlnGly: 3.385 ± 0.072	1.221GlnHis: 1.221 ± 0.037	2.394GlnIle: 2.394 ± 0.051	1.634GlnLys: 1.634 ± 0.049	4.953GlnLeu: 4.953 ± 0.084	1.109GlnMet: 1.109 ± 0.037	1.436GlnAsn: 1.436 ± 0.041	2.086GlnPro: 2.086 ± 0.053	2.966GlnGln: 2.966 ± 0.073	3.677GlnArg: 3.677 ± 0.078	2.548GlnSer: 2.548 ± 0.06	2.346GlnThr: 2.346 ± 0.057	3.332GlnVal: 3.332 ± 0.064	0.731GlnTrp: 0.731 ± 0.032	1.178GlnTyr: 1.178 ± 0.043	0.0GlnXaa: 0.0 ± 0.0
Arg	5.995ArgAla: 5.995 ± 0.102	0.497ArgCys: 0.497 ± 0.027	3.746ArgAsp: 3.746 ± 0.069	4.592ArgGlu: 4.592 ± 0.085	2.888ArgPhe: 2.888 ± 0.059	4.104ArgGly: 4.104 ± 0.082	1.605ArgHis: 1.605 ± 0.044	4.039ArgIle: 4.039 ± 0.076	2.298ArgLys: 2.298 ± 0.063	6.74ArgLeu: 6.74 ± 0.102	1.734ArgMet: 1.734 ± 0.047	2.111ArgAsn: 2.111 ± 0.056	2.519ArgPro: 2.519 ± 0.061	3.051ArgGln: 3.051 ± 0.064	3.902ArgArg: 3.902 ± 0.077	3.487ArgSer: 3.487 ± 0.066	3.063ArgThr: 3.063 ± 0.064	4.922ArgVal: 4.922 ± 0.088	1.106ArgTrp: 1.106 ± 0.045	2.121ArgTyr: 2.121 ± 0.051	0.0ArgXaa: 0.0 ± 0.0
Ser	5.587SerAla: 5.587 ± 0.097	0.436SerCys: 0.436 ± 0.027	3.291SerAsp: 3.291 ± 0.066	3.856SerGlu: 3.856 ± 0.079	2.408SerPhe: 2.408 ± 0.054	4.759SerGly: 4.759 ± 0.087	1.34SerHis: 1.34 ± 0.041	3.109SerIle: 3.109 ± 0.064	2.003SerLys: 2.003 ± 0.054	5.911SerLeu: 5.911 ± 0.099	1.579SerMet: 1.579 ± 0.041	1.81SerAsn: 1.81 ± 0.057	2.497SerPro: 2.497 ± 0.059	2.415SerGln: 2.415 ± 0.059	3.438SerArg: 3.438 ± 0.06	3.419SerSer: 3.419 ± 0.075	2.823SerThr: 2.823 ± 0.056	4.161SerVal: 4.161 ± 0.068	0.732SerTrp: 0.732 ± 0.032	1.552SerTyr: 1.552 ± 0.055	0.0SerXaa: 0.0 ± 0.0
Thr	4.678ThrAla: 4.678 ± 0.081	0.459ThrCys: 0.459 ± 0.027	2.904ThrAsp: 2.904 ± 0.064	3.298ThrGlu: 3.298 ± 0.066	2.123ThrPhe: 2.123 ± 0.061	4.335ThrGly: 4.335 ± 0.084	1.369ThrHis: 1.369 ± 0.044	3.096ThrIle: 3.096 ± 0.064	1.439ThrLys: 1.439 ± 0.047	6.184ThrLeu: 6.184 ± 0.093	1.118ThrMet: 1.118 ± 0.044	1.545ThrAsn: 1.545 ± 0.047	2.887ThrPro: 2.887 ± 0.064	2.319ThrGln: 2.319 ± 0.05	3.297ThrArg: 3.297 ± 0.065	2.944ThrSer: 2.944 ± 0.066	2.677ThrThr: 2.677 ± 0.07	3.856ThrVal: 3.856 ± 0.069	0.717ThrTrp: 0.717 ± 0.029	1.378ThrTyr: 1.378 ± 0.05	0.0ThrXaa: 0.0 ± 0.0
Val	6.984ValAla: 6.984 ± 0.103	0.608ValCys: 0.608 ± 0.03	3.927ValAsp: 3.927 ± 0.074	4.405ValGlu: 4.405 ± 0.079	2.911ValPhe: 2.911 ± 0.062	4.878ValGly: 4.878 ± 0.082	1.666ValHis: 1.666 ± 0.047	4.486ValIle: 4.486 ± 0.089	2.553ValLys: 2.553 ± 0.067	7.683ValLeu: 7.683 ± 0.119	1.99ValMet: 1.99 ± 0.049	2.664ValAsn: 2.664 ± 0.063	3.198ValPro: 3.198 ± 0.068	2.883ValGln: 2.883 ± 0.063	4.77ValArg: 4.77 ± 0.079	4.435ValSer: 4.435 ± 0.079	4.397ValThr: 4.397 ± 0.072	5.663ValVal: 5.663 ± 0.114	0.92ValTrp: 0.92 ± 0.036	1.83ValTyr: 1.83 ± 0.052	0.0ValXaa: 0.0 ± 0.0
Trp	0.917TrpAla: 0.917 ± 0.035	0.139TrpCys: 0.139 ± 0.012	0.696TrpAsp: 0.696 ± 0.03	0.671TrpGlu: 0.671 ± 0.03	0.777TrpPhe: 0.777 ± 0.03	0.807TrpGly: 0.807 ± 0.036	0.396TrpHis: 0.396 ± 0.024	0.814TrpIle: 0.814 ± 0.034	0.36TrpLys: 0.36 ± 0.02	1.916TrpLeu: 1.916 ± 0.054	0.386TrpMet: 0.386 ± 0.019	0.446TrpAsn: 0.446 ± 0.023	0.542TrpPro: 0.542 ± 0.03	0.932TrpGln: 0.932 ± 0.035	1.058TrpArg: 1.058 ± 0.04	0.838TrpSer: 0.838 ± 0.035	0.594TrpThr: 0.594 ± 0.029	1.01TrpVal: 1.01 ± 0.036	0.231TrpTrp: 0.231 ± 0.018	0.402TrpTyr: 0.402 ± 0.025	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.56TyrAla: 2.56 ± 0.064	0.267TyrCys: 0.267 ± 0.021	1.568TyrAsp: 1.568 ± 0.043	1.603TyrGlu: 1.603 ± 0.05	1.296TyrPhe: 1.296 ± 0.04	2.107TyrGly: 2.107 ± 0.057	0.768TyrHis: 0.768 ± 0.032	1.337TyrIle: 1.337 ± 0.043	0.769TyrLys: 0.769 ± 0.028	3.046TyrLeu: 3.046 ± 0.067	0.567TyrMet: 0.567 ± 0.025	0.862TyrAsn: 0.862 ± 0.036	1.308TyrPro: 1.308 ± 0.043	1.579TyrGln: 1.579 ± 0.047	2.078TyrArg: 2.078 ± 0.055	1.553TyrSer: 1.553 ± 0.043	1.415TyrThr: 1.415 ± 0.048	1.939TyrVal: 1.939 ± 0.055	0.451TyrTrp: 0.451 ± 0.022	0.797TyrTyr: 0.797 ± 0.036	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2334 proteins (782948 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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