Amino acid dipepetide frequency for Anabarilius grahami (Kanglang fish) (Barilius grahami)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.674AlaAla: 5.674 ± 0.039	1.295AlaCys: 1.295 ± 0.012	3.116AlaAsp: 3.116 ± 0.021	4.543AlaGlu: 4.543 ± 0.033	2.377AlaPhe: 2.377 ± 0.02	4.008AlaGly: 4.008 ± 0.029	1.567AlaHis: 1.567 ± 0.015	2.632AlaIle: 2.632 ± 0.018	3.209AlaLys: 3.209 ± 0.027	6.507AlaLeu: 6.507 ± 0.038	1.455AlaMet: 1.455 ± 0.012	2.059AlaAsn: 2.059 ± 0.013	3.464AlaPro: 3.464 ± 0.032	2.875AlaGln: 2.875 ± 0.021	3.105AlaArg: 3.105 ± 0.022	5.352AlaSer: 5.352 ± 0.029	3.449AlaThr: 3.449 ± 0.023	4.983AlaVal: 4.983 ± 0.027	0.63AlaTrp: 0.63 ± 0.008	1.4AlaTyr: 1.4 ± 0.014	0.001AlaXaa: 0.001 ± 0.0
Cys	1.267CysAla: 1.267 ± 0.013	0.676CysCys: 0.676 ± 0.01	1.179CysAsp: 1.179 ± 0.019	1.288CysGlu: 1.288 ± 0.015	0.914CysPhe: 0.914 ± 0.01	1.684CysGly: 1.684 ± 0.023	0.683CysHis: 0.683 ± 0.008	0.966CysIle: 0.966 ± 0.013	1.157CysLys: 1.157 ± 0.013	2.175CysLeu: 2.175 ± 0.019	0.498CysMet: 0.498 ± 0.008	0.837CysAsn: 0.837 ± 0.011	1.334CysPro: 1.334 ± 0.021	1.048CysGln: 1.048 ± 0.013	1.39CysArg: 1.39 ± 0.015	2.269CysSer: 2.269 ± 0.025	1.201CysThr: 1.201 ± 0.015	1.65CysVal: 1.65 ± 0.021	0.318CysTrp: 0.318 ± 0.006	0.619CysTyr: 0.619 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	2.951AspAla: 2.951 ± 0.02	1.156AspCys: 1.156 ± 0.016	2.99AspAsp: 2.99 ± 0.022	3.876AspGlu: 3.876 ± 0.026	2.042AspPhe: 2.042 ± 0.017	3.484AspGly: 3.484 ± 0.028	1.254AspHis: 1.254 ± 0.011	2.759AspIle: 2.759 ± 0.026	2.682AspLys: 2.682 ± 0.023	5.09AspLeu: 5.09 ± 0.029	1.259AspMet: 1.259 ± 0.013	1.867AspAsn: 1.867 ± 0.02	2.758AspPro: 2.758 ± 0.02	2.07AspGln: 2.07 ± 0.019	2.715AspArg: 2.715 ± 0.02	4.492AspSer: 4.492 ± 0.025	2.793AspThr: 2.793 ± 0.02	3.488AspVal: 3.488 ± 0.03	0.671AspTrp: 0.671 ± 0.01	1.427AspTyr: 1.427 ± 0.014	0.001AspXaa: 0.001 ± 0.0
Glu	4.305GluAla: 4.305 ± 0.033	1.268GluCys: 1.268 ± 0.017	4.401GluAsp: 4.401 ± 0.03	7.538GluGlu: 7.538 ± 0.072	2.007GluPhe: 2.007 ± 0.015	3.889GluGly: 3.889 ± 0.034	1.574GluHis: 1.574 ± 0.015	3.173GluIle: 3.173 ± 0.04	5.012GluLys: 5.012 ± 0.056	6.197GluLeu: 6.197 ± 0.045	1.866GluMet: 1.866 ± 0.018	2.958GluAsn: 2.958 ± 0.021	3.078GluPro: 3.078 ± 0.032	3.155GluGln: 3.155 ± 0.028	4.577GluArg: 4.577 ± 0.042	4.79GluSer: 4.79 ± 0.027	3.677GluThr: 3.677 ± 0.03	4.152GluVal: 4.152 ± 0.028	0.723GluTrp: 0.723 ± 0.008	1.534GluTyr: 1.534 ± 0.017	0.001GluXaa: 0.001 ± 0.0
Phe	1.855PheAla: 1.855 ± 0.017	0.966PheCys: 0.966 ± 0.011	1.705PheAsp: 1.705 ± 0.014	1.917PheGlu: 1.917 ± 0.019	1.511PhePhe: 1.511 ± 0.017	2.174PheGly: 2.174 ± 0.016	0.988PheHis: 0.988 ± 0.012	2.075PheIle: 2.075 ± 0.019	1.88PheLys: 1.88 ± 0.023	3.8PheLeu: 3.8 ± 0.027	0.833PheMet: 0.833 ± 0.01	1.458PheAsn: 1.458 ± 0.015	1.848PhePro: 1.848 ± 0.016	1.586PheGln: 1.586 ± 0.012	1.958PheArg: 1.958 ± 0.016	3.498PheSer: 3.498 ± 0.02	2.427PheThr: 2.427 ± 0.022	2.172PheVal: 2.172 ± 0.016	0.456PheTrp: 0.456 ± 0.008	1.136PheTyr: 1.136 ± 0.013	0.001PheXaa: 0.001 ± 0.0
Gly	3.626GlyAla: 3.626 ± 0.023	1.278GlyCys: 1.278 ± 0.015	3.045GlyAsp: 3.045 ± 0.025	3.933GlyGlu: 3.933 ± 0.036	2.31GlyPhe: 2.31 ± 0.017	4.388GlyGly: 4.388 ± 0.038	1.619GlyHis: 1.619 ± 0.015	2.55GlyIle: 2.55 ± 0.018	3.547GlyLys: 3.547 ± 0.027	5.27GlyLeu: 5.27 ± 0.031	1.364GlyMet: 1.364 ± 0.013	2.409GlyAsn: 2.409 ± 0.018	2.922GlyPro: 2.922 ± 0.05	2.65GlyGln: 2.65 ± 0.023	3.563GlyArg: 3.563 ± 0.025	5.43GlySer: 5.43 ± 0.035	3.216GlyThr: 3.216 ± 0.022	3.841GlyVal: 3.841 ± 0.025	0.764GlyTrp: 0.764 ± 0.011	1.652GlyTyr: 1.652 ± 0.016	0.002GlyXaa: 0.002 ± 0.0
His	1.389HisAla: 1.389 ± 0.013	0.781HisCys: 0.781 ± 0.011	1.011HisAsp: 1.011 ± 0.009	1.353HisGlu: 1.353 ± 0.014	1.099HisPhe: 1.099 ± 0.009	1.5HisGly: 1.5 ± 0.013	0.992HisHis: 0.992 ± 0.015	1.349HisIle: 1.349 ± 0.014	1.351HisLys: 1.351 ± 0.013	2.809HisLeu: 2.809 ± 0.02	0.749HisMet: 0.749 ± 0.014	1.066HisAsn: 1.066 ± 0.011	1.548HisPro: 1.548 ± 0.015	1.302HisGln: 1.302 ± 0.011	1.622HisArg: 1.622 ± 0.016	2.48HisSer: 2.48 ± 0.02	1.809HisThr: 1.809 ± 0.021	1.547HisVal: 1.547 ± 0.016	0.342HisTrp: 0.342 ± 0.006	0.801HisTyr: 0.801 ± 0.009	0.0HisXaa: 0.0 ± 0.0
Ile	2.542IleAla: 2.542 ± 0.017	1.165IleCys: 1.165 ± 0.013	2.125IleAsp: 2.125 ± 0.019	2.598IleGlu: 2.598 ± 0.03	1.792IlePhe: 1.792 ± 0.016	2.286IleGly: 2.286 ± 0.017	1.438IleHis: 1.438 ± 0.018	2.443IleIle: 2.443 ± 0.019	2.728IleLys: 2.728 ± 0.028	4.318IleLeu: 4.318 ± 0.03	1.108IleMet: 1.108 ± 0.013	2.046IleAsn: 2.046 ± 0.016	2.504IlePro: 2.504 ± 0.016	2.241IleGln: 2.241 ± 0.018	2.518IleArg: 2.518 ± 0.016	4.182IleSer: 4.182 ± 0.024	3.014IleThr: 3.014 ± 0.022	2.599IleVal: 2.599 ± 0.022	0.521IleTrp: 0.521 ± 0.008	1.371IleTyr: 1.371 ± 0.012	0.001IleXaa: 0.001 ± 0.0
Lys	3.696LysAla: 3.696 ± 0.031	1.105LysCys: 1.105 ± 0.013	3.279LysAsp: 3.279 ± 0.028	4.768LysGlu: 4.768 ± 0.05	1.562LysPhe: 1.562 ± 0.016	3.108LysGly: 3.108 ± 0.036	1.515LysHis: 1.515 ± 0.013	2.647LysIle: 2.647 ± 0.025	4.448LysLys: 4.448 ± 0.041	4.997LysLeu: 4.997 ± 0.029	1.545LysMet: 1.545 ± 0.019	2.387LysAsn: 2.387 ± 0.02	3.072LysPro: 3.072 ± 0.034	2.623LysGln: 2.623 ± 0.025	3.69LysArg: 3.69 ± 0.026	4.186LysSer: 4.186 ± 0.027	3.41LysThr: 3.41 ± 0.025	3.332LysVal: 3.332 ± 0.024	0.607LysTrp: 0.607 ± 0.008	1.45LysTyr: 1.45 ± 0.016	0.001LysXaa: 0.001 ± 0.0
Leu	5.611LeuAla: 5.611 ± 0.03	2.264LeuCys: 2.264 ± 0.019	4.75LeuAsp: 4.75 ± 0.029	6.396LeuGlu: 6.396 ± 0.051	3.358LeuPhe: 3.358 ± 0.025	4.677LeuGly: 4.677 ± 0.025	2.751LeuHis: 2.751 ± 0.02	4.016LeuIle: 4.016 ± 0.023	5.866LeuLys: 5.866 ± 0.034	9.56LeuLeu: 9.56 ± 0.055	2.168LeuMet: 2.168 ± 0.015	3.798LeuAsn: 3.798 ± 0.022	5.311LeuPro: 5.311 ± 0.031	5.455LeuGln: 5.455 ± 0.038	5.725LeuArg: 5.725 ± 0.033	8.409LeuSer: 8.409 ± 0.039	5.312LeuThr: 5.312 ± 0.028	5.314LeuVal: 5.314 ± 0.033	1.096LeuTrp: 1.096 ± 0.013	2.478LeuTyr: 2.478 ± 0.022	0.002LeuXaa: 0.002 ± 0.0
Met	1.882MetAla: 1.882 ± 0.015	0.507MetCys: 0.507 ± 0.008	1.478MetAsp: 1.478 ± 0.016	1.988MetGlu: 1.988 ± 0.019	0.854MetPhe: 0.854 ± 0.009	1.334MetGly: 1.334 ± 0.014	0.501MetHis: 0.501 ± 0.007	0.969MetIle: 0.969 ± 0.01	1.58MetLys: 1.58 ± 0.017	1.98MetLeu: 1.98 ± 0.017	0.698MetMet: 0.698 ± 0.009	0.972MetAsn: 0.972 ± 0.01	1.111MetPro: 1.111 ± 0.019	0.998MetGln: 0.998 ± 0.011	1.352MetArg: 1.352 ± 0.014	1.948MetSer: 1.948 ± 0.016	1.323MetThr: 1.323 ± 0.013	1.454MetVal: 1.454 ± 0.014	0.258MetTrp: 0.258 ± 0.005	0.602MetTyr: 0.602 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	2.197AsnAla: 2.197 ± 0.018	0.895AsnCys: 0.895 ± 0.012	1.788AsnAsp: 1.788 ± 0.018	2.349AsnGlu: 2.349 ± 0.021	1.366AsnPhe: 1.366 ± 0.013	2.681AsnGly: 2.681 ± 0.025	1.023AsnHis: 1.023 ± 0.011	2.264AsnIle: 2.264 ± 0.019	2.256AsnLys: 2.256 ± 0.019	3.637AsnLeu: 3.637 ± 0.023	1.056AsnMet: 1.056 ± 0.012	1.838AsnAsn: 1.838 ± 0.02	2.187AsnPro: 2.187 ± 0.02	1.748AsnGln: 1.748 ± 0.015	2.071AsnArg: 2.071 ± 0.015	3.267AsnSer: 3.267 ± 0.022	2.444AsnThr: 2.444 ± 0.016	2.356AsnVal: 2.356 ± 0.02	0.447AsnTrp: 0.447 ± 0.006	1.087AsnTyr: 1.087 ± 0.013	0.001AsnXaa: 0.001 ± 0.0
Pro	4.133ProAla: 4.133 ± 0.035	1.103ProCys: 1.103 ± 0.013	2.847ProAsp: 2.847 ± 0.024	3.851ProGlu: 3.851 ± 0.028	1.862ProPhe: 1.862 ± 0.016	3.498ProGly: 3.498 ± 0.049	1.442ProHis: 1.442 ± 0.015	1.937ProIle: 1.937 ± 0.016	2.603ProLys: 2.603 ± 0.04	4.819ProLeu: 4.819 ± 0.028	1.087ProMet: 1.087 ± 0.014	1.872ProAsn: 1.872 ± 0.016	4.966ProPro: 4.966 ± 0.053	2.55ProGln: 2.55 ± 0.022	2.697ProArg: 2.697 ± 0.023	5.599ProSer: 5.599 ± 0.037	3.053ProThr: 3.053 ± 0.03	4.048ProVal: 4.048 ± 0.03	0.623ProTrp: 0.623 ± 0.012	1.39ProTyr: 1.39 ± 0.014	0.004ProXaa: 0.004 ± 0.001
Gln	2.954GlnAla: 2.954 ± 0.023	1.161GlnCys: 1.161 ± 0.018	2.317GlnAsp: 2.317 ± 0.018	3.497GlnGlu: 3.497 ± 0.029	1.322GlnPhe: 1.322 ± 0.013	2.473GlnGly: 2.473 ± 0.022	1.375GlnHis: 1.375 ± 0.014	2.05GlnIle: 2.05 ± 0.016	2.781GlnLys: 2.781 ± 0.031	4.23GlnLeu: 4.23 ± 0.03	1.184GlnMet: 1.184 ± 0.014	1.937GlnAsn: 1.937 ± 0.017	2.477GlnPro: 2.477 ± 0.024	2.967GlnGln: 2.967 ± 0.036	3.132GlnArg: 3.132 ± 0.023	3.705GlnSer: 3.705 ± 0.028	2.882GlnThr: 2.882 ± 0.021	2.577GlnVal: 2.577 ± 0.021	0.559GlnTrp: 0.559 ± 0.007	1.184GlnTyr: 1.184 ± 0.013	0.0GlnXaa: 0.0 ± 0.0
Arg	3.554ArgAla: 3.554 ± 0.021	1.281ArgCys: 1.281 ± 0.015	2.927ArgAsp: 2.927 ± 0.022	4.13ArgGlu: 4.13 ± 0.034	2.14ArgPhe: 2.14 ± 0.017	3.301ArgGly: 3.301 ± 0.027	1.628ArgHis: 1.628 ± 0.015	2.545ArgIle: 2.545 ± 0.017	3.694ArgLys: 3.694 ± 0.024	5.308ArgLeu: 5.308 ± 0.029	1.309ArgMet: 1.309 ± 0.012	2.171ArgAsn: 2.171 ± 0.015	3.004ArgPro: 3.004 ± 0.024	2.659ArgGln: 2.659 ± 0.022	4.522ArgArg: 4.522 ± 0.032	4.786ArgSer: 4.786 ± 0.031	2.943ArgThr: 2.943 ± 0.017	3.429ArgVal: 3.429 ± 0.021	0.715ArgTrp: 0.715 ± 0.011	1.495ArgTyr: 1.495 ± 0.012	0.002ArgXaa: 0.002 ± 0.0
Ser	5.957SerAla: 5.957 ± 0.03	2.04SerCys: 2.04 ± 0.018	4.623SerAsp: 4.623 ± 0.031	5.42SerGlu: 5.42 ± 0.033	3.289SerPhe: 3.289 ± 0.027	5.62SerGly: 5.62 ± 0.034	2.305SerHis: 2.305 ± 0.019	3.557SerIle: 3.557 ± 0.021	4.054SerLys: 4.054 ± 0.026	8.333SerLeu: 8.333 ± 0.04	1.844SerMet: 1.844 ± 0.013	3.061SerAsn: 3.061 ± 0.023	5.741SerPro: 5.741 ± 0.046	3.85SerGln: 3.85 ± 0.027	4.646SerArg: 4.646 ± 0.028	10.241SerSer: 10.241 ± 0.065	5.048SerThr: 5.048 ± 0.034	5.955SerVal: 5.955 ± 0.03	1.011SerTrp: 1.011 ± 0.012	2.105SerTyr: 2.105 ± 0.019	0.002SerXaa: 0.002 ± 0.0
Thr	4.183ThrAla: 4.183 ± 0.024	1.416ThrCys: 1.416 ± 0.02	3.18ThrAsp: 3.18 ± 0.025	4.099ThrGlu: 4.099 ± 0.032	2.203ThrPhe: 2.203 ± 0.02	3.818ThrGly: 3.818 ± 0.03	1.58ThrHis: 1.58 ± 0.017	2.519ThrIle: 2.519 ± 0.02	2.677ThrLys: 2.677 ± 0.024	5.415ThrLeu: 5.415 ± 0.024	1.188ThrMet: 1.188 ± 0.013	2.016ThrAsn: 2.016 ± 0.023	3.599ThrPro: 3.599 ± 0.031	2.517ThrGln: 2.517 ± 0.021	2.619ThrArg: 2.619 ± 0.016	5.012ThrSer: 5.012 ± 0.033	3.445ThrThr: 3.445 ± 0.051	4.359ThrVal: 4.359 ± 0.029	0.634ThrTrp: 0.634 ± 0.01	1.392ThrTyr: 1.392 ± 0.013	0.001ThrXaa: 0.001 ± 0.0
Val	3.863ValAla: 3.863 ± 0.023	1.825ValCys: 1.825 ± 0.018	3.143ValAsp: 3.143 ± 0.022	4.067ValGlu: 4.067 ± 0.03	2.648ValPhe: 2.648 ± 0.021	3.284ValGly: 3.284 ± 0.022	1.659ValHis: 1.659 ± 0.015	3.065ValIle: 3.065 ± 0.025	3.694ValLys: 3.694 ± 0.029	6.295ValLeu: 6.295 ± 0.034	1.567ValMet: 1.567 ± 0.012	2.525ValAsn: 2.525 ± 0.021	3.312ValPro: 3.312 ± 0.023	2.856ValGln: 2.856 ± 0.02	3.269ValArg: 3.269 ± 0.018	5.693ValSer: 5.693 ± 0.029	4.077ValThr: 4.077 ± 0.037	4.144ValVal: 4.144 ± 0.029	0.79ValTrp: 0.79 ± 0.009	1.834ValTyr: 1.834 ± 0.016	0.001ValXaa: 0.001 ± 0.0
Trp	0.695TrpAla: 0.695 ± 0.01	0.254TrpCys: 0.254 ± 0.005	0.625TrpAsp: 0.625 ± 0.009	0.71TrpGlu: 0.71 ± 0.009	0.46TrpPhe: 0.46 ± 0.007	0.609TrpGly: 0.609 ± 0.01	0.279TrpHis: 0.279 ± 0.005	0.616TrpIle: 0.616 ± 0.009	0.752TrpLys: 0.752 ± 0.009	1.167TrpLeu: 1.167 ± 0.013	0.348TrpMet: 0.348 ± 0.007	0.507TrpAsn: 0.507 ± 0.009	0.488TrpPro: 0.488 ± 0.008	0.458TrpGln: 0.458 ± 0.007	0.801TrpArg: 0.801 ± 0.01	1.016TrpSer: 1.016 ± 0.012	0.739TrpThr: 0.739 ± 0.011	0.672TrpVal: 0.672 ± 0.01	0.18TrpTrp: 0.18 ± 0.004	0.343TrpTyr: 0.343 ± 0.007	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.369TyrAla: 1.369 ± 0.013	0.72TyrCys: 0.72 ± 0.01	1.294TyrAsp: 1.294 ± 0.012	1.552TyrGlu: 1.552 ± 0.015	1.125TyrPhe: 1.125 ± 0.012	1.561TyrGly: 1.561 ± 0.016	0.731TyrHis: 0.731 ± 0.009	1.403TyrIle: 1.403 ± 0.015	1.456TyrLys: 1.456 ± 0.018	2.405TyrLeu: 2.405 ± 0.018	0.664TyrMet: 0.664 ± 0.009	1.167TyrAsn: 1.167 ± 0.014	1.258TyrPro: 1.258 ± 0.013	1.155TyrGln: 1.155 ± 0.013	1.568TyrArg: 1.568 ± 0.014	2.348TyrSer: 2.348 ± 0.018	1.61TyrThr: 1.61 ± 0.016	1.54TyrVal: 1.54 ± 0.012	0.373TyrTrp: 0.373 ± 0.008	0.894TyrTyr: 0.894 ± 0.01	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.0	0.001XaaCys: 0.001 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.001XaaGlu: 0.001 ± 0.0	0.001XaaPhe: 0.001 ± 0.0	0.002XaaGly: 0.002 ± 0.0	0.001XaaHis: 0.001 ± 0.0	0.001XaaIle: 0.001 ± 0.0	0.001XaaLys: 0.001 ± 0.0	0.002XaaLeu: 0.002 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.003XaaPro: 0.003 ± 0.0	0.001XaaGln: 0.001 ± 0.0	0.002XaaArg: 0.002 ± 0.0	0.002XaaSer: 0.002 ± 0.0	0.001XaaThr: 0.001 ± 0.0	0.001XaaVal: 0.001 ± 0.0	0.001XaaTrp: 0.001 ± 0.0	0.001XaaTyr: 0.001 ± 0.0	0.479XaaXaa: 0.479 ± 0.117

Statistics based on 23663 proteins (11186444 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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