Amino acid dipepetide frequency for Medicago sativa amalgavirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.892AlaAla: 6.892 ± 3.141
2.068AlaCys: 2.068 ± 1.117
4.135AlaAsp: 4.135 ± 0.512
5.513AlaGlu: 5.513 ± 2.513
1.378AlaPhe: 1.378 ± 0.745
6.203AlaGly: 6.203 ± 2.14
3.446AlaHis: 3.446 ± 0.884
6.892AlaIle: 6.892 ± 3.141
2.757AlaLys: 2.757 ± 1.256
9.649AlaLeu: 9.649 ± 0.279
0.0AlaMet: 0.0 ± 0.0
3.446AlaAsn: 3.446 ± 0.884
3.446AlaPro: 3.446 ± 0.489
4.135AlaGln: 4.135 ± 1.885
6.892AlaArg: 6.892 ± 0.977
3.446AlaSer: 3.446 ± 0.489
2.068AlaThr: 2.068 ± 0.256
8.959AlaVal: 8.959 ± 0.721
1.378AlaTrp: 1.378 ± 0.745
3.446AlaTyr: 3.446 ± 0.884
0.0AlaXaa: 0.0 ± 0.0
Cys
4.824CysAla: 4.824 ± 0.14
0.689CysCys: 0.689 ± 0.372
1.378CysAsp: 1.378 ± 0.628
0.0CysGlu: 0.0 ± 0.0
1.378CysPhe: 1.378 ± 0.745
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.689CysIle: 0.689 ± 0.372
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.689CysAsn: 0.689 ± 0.372
0.689CysPro: 0.689 ± 0.372
0.0CysGln: 0.0 ± 0.0
2.068CysArg: 2.068 ± 0.256
0.689CysSer: 0.689 ± 0.372
0.0CysThr: 0.0 ± 0.0
0.689CysVal: 0.689 ± 0.372
0.0CysTrp: 0.0 ± 0.0
0.689CysTyr: 0.689 ± 0.372
0.0CysXaa: 0.0 ± 0.0
Asp
7.581AspAla: 7.581 ± 1.35
1.378AspCys: 1.378 ± 0.628
7.581AspAsp: 7.581 ± 1.396
4.824AspGlu: 4.824 ± 0.14
6.892AspPhe: 6.892 ± 0.395
5.513AspGly: 5.513 ± 0.233
0.0AspHis: 0.0 ± 0.0
1.378AspIle: 1.378 ± 0.745
0.689AspLys: 0.689 ± 0.372
5.513AspLeu: 5.513 ± 0.233
1.378AspMet: 1.378 ± 0.628
5.513AspAsn: 5.513 ± 0.233
4.135AspPro: 4.135 ± 0.512
1.378AspGln: 1.378 ± 2.001
0.689AspArg: 0.689 ± 0.372
2.068AspSer: 2.068 ± 0.256
2.068AspThr: 2.068 ± 0.256
3.446AspVal: 3.446 ± 0.489
2.068AspTrp: 2.068 ± 1.117
3.446AspTyr: 3.446 ± 0.884
0.0AspXaa: 0.0 ± 0.0
Glu
6.203GluAla: 6.203 ± 0.768
0.689GluCys: 0.689 ± 0.372
4.824GluAsp: 4.824 ± 0.14
8.27GluGlu: 8.27 ± 2.396
2.757GluPhe: 2.757 ± 0.116
8.959GluGly: 8.959 ± 2.094
0.689GluHis: 0.689 ± 0.372
3.446GluIle: 3.446 ± 0.884
6.203GluLys: 6.203 ± 0.605
9.649GluLeu: 9.649 ± 1.652
1.378GluMet: 1.378 ± 0.49
0.689GluAsn: 0.689 ± 0.372
1.378GluPro: 1.378 ± 0.745
1.378GluGln: 1.378 ± 0.628
8.27GluArg: 8.27 ± 2.396
1.378GluSer: 1.378 ± 0.628
1.378GluThr: 1.378 ± 0.745
2.757GluVal: 2.757 ± 0.116
0.0GluTrp: 0.0 ± 0.0
0.689GluTyr: 0.689 ± 0.372
0.0GluXaa: 0.0 ± 0.0
Phe
2.068PheAla: 2.068 ± 1.117
2.757PheCys: 2.757 ± 1.256
2.068PheAsp: 2.068 ± 0.256
3.446PheGlu: 3.446 ± 0.884
0.0PhePhe: 0.0 ± 0.0
5.513PheGly: 5.513 ± 1.605
0.689PheHis: 0.689 ± 0.372
2.757PheIle: 2.757 ± 0.116
2.068PheLys: 2.068 ± 1.117
4.135PheLeu: 4.135 ± 0.861
2.068PheMet: 2.068 ± 1.117
4.135PheAsn: 4.135 ± 0.512
4.135PhePro: 4.135 ± 0.512
0.0PheGln: 0.0 ± 0.0
4.135PheArg: 4.135 ± 0.861
1.378PheSer: 1.378 ± 0.745
0.0PheThr: 0.0 ± 0.0
4.135PheVal: 4.135 ± 0.512
1.378PheTrp: 1.378 ± 0.628
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
4.135GlyAla: 4.135 ± 0.861
1.378GlyCys: 1.378 ± 0.745
4.135GlyAsp: 4.135 ± 2.234
6.892GlyGlu: 6.892 ± 1.768
4.824GlyPhe: 4.824 ± 0.14
10.338GlyGly: 10.338 ± 0.093
0.0GlyHis: 0.0 ± 0.0
2.068GlyIle: 2.068 ± 1.117
1.378GlyLys: 1.378 ± 0.745
4.135GlyLeu: 4.135 ± 0.861
3.446GlyMet: 3.446 ± 0.489
6.203GlyAsn: 6.203 ± 2.14
4.135GlyPro: 4.135 ± 0.512
1.378GlyGln: 1.378 ± 0.628
6.203GlyArg: 6.203 ± 0.605
3.446GlySer: 3.446 ± 0.489
1.378GlyThr: 1.378 ± 0.745
5.513GlyVal: 5.513 ± 1.605
0.689GlyTrp: 0.689 ± 0.372
4.135GlyTyr: 4.135 ± 0.512
0.0GlyXaa: 0.0 ± 0.0
His
0.689HisAla: 0.689 ± 0.372
0.0HisCys: 0.0 ± 0.0
2.068HisAsp: 2.068 ± 1.117
0.689HisGlu: 0.689 ± 0.372
1.378HisPhe: 1.378 ± 0.628
1.378HisGly: 1.378 ± 0.628
2.068HisHis: 2.068 ± 1.117
1.378HisIle: 1.378 ± 0.745
1.378HisLys: 1.378 ± 0.745
1.378HisLeu: 1.378 ± 0.628
0.689HisMet: 0.689 ± 0.372
2.068HisAsn: 2.068 ± 0.256
0.689HisPro: 0.689 ± 0.372
0.0HisGln: 0.0 ± 0.0
1.378HisArg: 1.378 ± 0.745
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
1.378HisVal: 1.378 ± 0.628
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.135IleAla: 4.135 ± 1.885
0.0IleCys: 0.0 ± 0.0
3.446IleAsp: 3.446 ± 0.884
2.068IleGlu: 2.068 ± 0.256
2.068IlePhe: 2.068 ± 0.256
2.757IleGly: 2.757 ± 0.116
0.689IleHis: 0.689 ± 0.372
3.446IleIle: 3.446 ± 0.489
4.135IleLys: 4.135 ± 0.512
0.689IleLeu: 0.689 ± 0.372
0.0IleMet: 0.0 ± 0.0
0.0IleAsn: 0.0 ± 0.0
2.068IlePro: 2.068 ± 1.117
0.689IleGln: 0.689 ± 0.372
4.135IleArg: 4.135 ± 2.234
5.513IleSer: 5.513 ± 1.605
3.446IleThr: 3.446 ± 0.884
3.446IleVal: 3.446 ± 2.257
0.689IleTrp: 0.689 ± 0.372
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
6.892LysAla: 6.892 ± 0.977
0.0LysCys: 0.0 ± 0.0
3.446LysAsp: 3.446 ± 0.489
0.0LysGlu: 0.0 ± 0.0
2.068LysPhe: 2.068 ± 1.117
1.378LysGly: 1.378 ± 0.628
1.378LysHis: 1.378 ± 0.745
3.446LysIle: 3.446 ± 0.489
6.892LysLys: 6.892 ± 1.768
3.446LysLeu: 3.446 ± 1.861
0.0LysMet: 0.0 ± 0.0
2.068LysAsn: 2.068 ± 1.117
2.068LysPro: 2.068 ± 0.256
4.135LysGln: 4.135 ± 1.885
2.757LysArg: 2.757 ± 1.256
6.892LysSer: 6.892 ± 1.768
2.068LysThr: 2.068 ± 0.256
4.824LysVal: 4.824 ± 0.14
2.068LysTrp: 2.068 ± 0.256
2.757LysTyr: 2.757 ± 0.116
0.0LysXaa: 0.0 ± 0.0
Leu
3.446LeuAla: 3.446 ± 0.489
1.378LeuCys: 1.378 ± 0.628
5.513LeuAsp: 5.513 ± 0.233
6.203LeuGlu: 6.203 ± 1.978
2.068LeuPhe: 2.068 ± 0.256
3.446LeuGly: 3.446 ± 0.489
2.757LeuHis: 2.757 ± 1.489
2.757LeuIle: 2.757 ± 0.116
4.135LeuLys: 4.135 ± 0.861
10.338LeuLeu: 10.338 ± 0.093
3.446LeuMet: 3.446 ± 0.489
6.203LeuAsn: 6.203 ± 0.605
2.068LeuPro: 2.068 ± 1.117
4.824LeuGln: 4.824 ± 1.512
10.338LeuArg: 10.338 ± 1.466
7.581LeuSer: 7.581 ± 0.023
0.689LeuThr: 0.689 ± 0.372
3.446LeuVal: 3.446 ± 0.884
1.378LeuTrp: 1.378 ± 0.745
3.446LeuTyr: 3.446 ± 0.489
0.0LeuXaa: 0.0 ± 0.0
Met
2.757MetAla: 2.757 ± 1.256
0.689MetCys: 0.689 ± 0.372
1.378MetAsp: 1.378 ± 0.745
1.378MetGlu: 1.378 ± 0.745
0.689MetPhe: 0.689 ± 0.372
1.378MetGly: 1.378 ± 0.628
0.0MetHis: 0.0 ± 0.0
0.689MetIle: 0.689 ± 0.372
0.689MetLys: 0.689 ± 0.372
1.378MetLeu: 1.378 ± 0.745
1.378MetMet: 1.378 ± 0.745
0.0MetAsn: 0.0 ± 0.0
0.689MetPro: 0.689 ± 0.372
0.689MetGln: 0.689 ± 0.372
0.0MetArg: 0.0 ± 0.0
3.446MetSer: 3.446 ± 0.884
0.0MetThr: 0.0 ± 0.0
2.068MetVal: 2.068 ± 1.117
0.0MetTrp: 0.0 ± 0.0
2.068MetTyr: 2.068 ± 0.256
0.0MetXaa: 0.0 ± 0.0
Asn
6.892AsnAla: 6.892 ± 1.768
0.689AsnCys: 0.689 ± 0.372
2.068AsnAsp: 2.068 ± 1.117
0.0AsnGlu: 0.0 ± 0.0
4.135AsnPhe: 4.135 ± 0.512
1.378AsnGly: 1.378 ± 0.745
1.378AsnHis: 1.378 ± 0.745
2.068AsnIle: 2.068 ± 0.256
3.446AsnLys: 3.446 ± 2.257
2.068AsnLeu: 2.068 ± 1.117
0.0AsnMet: 0.0 ± 0.0
2.068AsnAsn: 2.068 ± 0.256
2.068AsnPro: 2.068 ± 0.256
2.068AsnGln: 2.068 ± 1.629
2.757AsnArg: 2.757 ± 0.116
1.378AsnSer: 1.378 ± 0.745
1.378AsnThr: 1.378 ± 0.628
2.068AsnVal: 2.068 ± 0.256
1.378AsnTrp: 1.378 ± 0.745
1.378AsnTyr: 1.378 ± 0.628
0.0AsnXaa: 0.0 ± 0.0
Pro
2.757ProAla: 2.757 ± 1.256
0.0ProCys: 0.0 ± 0.0
3.446ProAsp: 3.446 ± 0.489
4.824ProGlu: 4.824 ± 1.233
2.068ProPhe: 2.068 ± 0.256
4.135ProGly: 4.135 ± 2.234
1.378ProHis: 1.378 ± 0.628
5.513ProIle: 5.513 ± 1.14
2.068ProLys: 2.068 ± 1.117
5.513ProLeu: 5.513 ± 0.233
0.689ProMet: 0.689 ± 0.372
0.0ProAsn: 0.0 ± 0.0
1.378ProPro: 1.378 ± 0.628
1.378ProGln: 1.378 ± 0.628
0.689ProArg: 0.689 ± 0.372
0.689ProSer: 0.689 ± 0.372
0.689ProThr: 0.689 ± 0.372
5.513ProVal: 5.513 ± 0.233
1.378ProTrp: 1.378 ± 0.745
1.378ProTyr: 1.378 ± 0.745
0.0ProXaa: 0.0 ± 0.0
Gln
6.892GlnAla: 6.892 ± 3.141
0.689GlnCys: 0.689 ± 0.372
3.446GlnAsp: 3.446 ± 2.257
2.068GlnGlu: 2.068 ± 1.629
1.378GlnPhe: 1.378 ± 0.745
3.446GlnGly: 3.446 ± 0.489
0.0GlnHis: 0.0 ± 0.0
1.378GlnIle: 1.378 ± 2.001
2.068GlnLys: 2.068 ± 1.629
4.135GlnLeu: 4.135 ± 0.512
1.378GlnMet: 1.378 ± 0.628
0.0GlnAsn: 0.0 ± 0.0
1.378GlnPro: 1.378 ± 2.001
1.378GlnGln: 1.378 ± 0.628
4.135GlnArg: 4.135 ± 1.885
0.689GlnSer: 0.689 ± 0.372
2.068GlnThr: 2.068 ± 1.629
1.378GlnVal: 1.378 ± 0.628
0.0GlnTrp: 0.0 ± 0.0
1.378GlnTyr: 1.378 ± 0.628
0.0GlnXaa: 0.0 ± 0.0
Arg
7.581ArgAla: 7.581 ± 0.023
0.0ArgCys: 0.0 ± 0.0
6.203ArgAsp: 6.203 ± 0.768
10.338ArgGlu: 10.338 ± 1.28
4.135ArgPhe: 4.135 ± 0.512
5.513ArgGly: 5.513 ± 1.605
0.0ArgHis: 0.0 ± 0.0
1.378ArgIle: 1.378 ± 0.745
4.135ArgLys: 4.135 ± 0.512
6.203ArgLeu: 6.203 ± 1.978
0.689ArgMet: 0.689 ± 0.372
1.378ArgAsn: 1.378 ± 0.628
4.824ArgPro: 4.824 ± 2.606
4.824ArgGln: 4.824 ± 1.512
8.27ArgArg: 8.27 ± 2.396
8.959ArgSer: 8.959 ± 0.721
1.378ArgThr: 1.378 ± 2.001
4.135ArgVal: 4.135 ± 0.512
2.068ArgTrp: 2.068 ± 1.117
0.0ArgTyr: 0.0 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
2.068SerAla: 2.068 ± 0.256
1.378SerCys: 1.378 ± 0.745
6.892SerAsp: 6.892 ± 1.768
2.068SerGlu: 2.068 ± 1.117
2.757SerPhe: 2.757 ± 0.116
6.203SerGly: 6.203 ± 0.605
0.689SerHis: 0.689 ± 0.372
1.378SerIle: 1.378 ± 0.745
4.824SerLys: 4.824 ± 1.233
4.135SerLeu: 4.135 ± 0.512
1.378SerMet: 1.378 ± 0.745
1.378SerAsn: 1.378 ± 0.745
2.068SerPro: 2.068 ± 0.256
1.378SerGln: 1.378 ± 0.628
6.203SerArg: 6.203 ± 0.768
6.892SerSer: 6.892 ± 0.977
4.135SerThr: 4.135 ± 0.861
3.446SerVal: 3.446 ± 0.489
2.068SerTrp: 2.068 ± 1.117
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
3.446ThrAla: 3.446 ± 0.884
0.0ThrCys: 0.0 ± 0.0
0.689ThrAsp: 0.689 ± 0.372
2.068ThrGlu: 2.068 ± 0.256
2.757ThrPhe: 2.757 ± 0.116
2.068ThrGly: 2.068 ± 0.256
0.0ThrHis: 0.0 ± 0.0
0.0ThrIle: 0.0 ± 0.0
3.446ThrLys: 3.446 ± 0.884
1.378ThrLeu: 1.378 ± 0.745
0.0ThrMet: 0.0 ± 0.0
0.689ThrAsn: 0.689 ± 0.372
2.068ThrPro: 2.068 ± 0.256
2.068ThrGln: 2.068 ± 1.629
2.068ThrArg: 2.068 ± 0.256
3.446ThrSer: 3.446 ± 0.489
0.689ThrThr: 0.689 ± 0.372
2.068ThrVal: 2.068 ± 0.256
0.0ThrTrp: 0.0 ± 0.0
0.689ThrTyr: 0.689 ± 0.372
0.0ThrXaa: 0.0 ± 0.0
Val
6.203ValAla: 6.203 ± 3.513
0.689ValCys: 0.689 ± 0.372
2.068ValAsp: 2.068 ± 1.117
6.892ValGlu: 6.892 ± 0.977
2.068ValPhe: 2.068 ± 1.117
4.824ValGly: 4.824 ± 0.14
2.757ValHis: 2.757 ± 1.256
2.757ValIle: 2.757 ± 1.489
6.203ValLys: 6.203 ± 0.768
2.068ValLeu: 2.068 ± 1.117
2.068ValMet: 2.068 ± 0.329
1.378ValAsn: 1.378 ± 2.001
3.446ValPro: 3.446 ± 0.489
2.757ValGln: 2.757 ± 1.256
7.581ValArg: 7.581 ± 0.023
2.068ValSer: 2.068 ± 1.117
2.757ValThr: 2.757 ± 0.116
3.446ValVal: 3.446 ± 0.489
0.689ValTrp: 0.689 ± 0.372
1.378ValTyr: 1.378 ± 0.745
0.0ValXaa: 0.0 ± 0.0
Trp
0.689TrpAla: 0.689 ± 0.372
0.0TrpCys: 0.0 ± 0.0
1.378TrpAsp: 1.378 ± 0.628
1.378TrpGlu: 1.378 ± 0.745
1.378TrpPhe: 1.378 ± 0.745
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.689TrpLys: 0.689 ± 0.372
5.513TrpLeu: 5.513 ± 1.605
0.0TrpMet: 0.0 ± 0.0
0.689TrpAsn: 0.689 ± 0.372
1.378TrpPro: 1.378 ± 0.745
0.689TrpGln: 0.689 ± 0.372
0.689TrpArg: 0.689 ± 0.372
0.689TrpSer: 0.689 ± 0.372
0.689TrpThr: 0.689 ± 0.372
1.378TrpVal: 1.378 ± 0.745
1.378TrpTrp: 1.378 ± 0.745
0.689TrpTyr: 0.689 ± 0.372
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
0.0TyrCys: 0.0 ± 0.0
1.378TyrAsp: 1.378 ± 0.628
2.757TyrGlu: 2.757 ± 0.116
0.689TyrPhe: 0.689 ± 0.372
1.378TyrGly: 1.378 ± 0.628
0.689TyrHis: 0.689 ± 0.372
0.0TyrIle: 0.0 ± 0.0
1.378TyrLys: 1.378 ± 0.745
4.135TyrLeu: 4.135 ± 0.512
0.689TyrMet: 0.689 ± 0.372
2.068TyrAsn: 2.068 ± 0.256
1.378TyrPro: 1.378 ± 0.745
4.135TyrGln: 4.135 ± 1.885
2.757TyrArg: 2.757 ± 0.116
0.689TyrSer: 0.689 ± 0.372
2.757TyrThr: 2.757 ± 0.116
0.0TyrVal: 0.0 ± 0.0
0.689TyrTrp: 0.689 ± 0.372
1.378TyrTyr: 1.378 ± 0.628
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1452 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski