Amino acid dipepetide frequency for Campylobacter hominis (strain ATCC BAA-381 / LMG 19568 / NCTC 13146 / CH001A)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.233AlaAla: 4.233 ± 0.12
0.783AlaCys: 0.783 ± 0.045
3.406AlaAsp: 3.406 ± 0.091
3.57AlaGlu: 3.57 ± 0.087
3.518AlaPhe: 3.518 ± 0.097
4.22AlaGly: 4.22 ± 0.124
1.055AlaHis: 1.055 ± 0.047
6.1AlaIle: 6.1 ± 0.116
7.431AlaLys: 7.431 ± 0.155
7.049AlaLeu: 7.049 ± 0.125
1.749AlaMet: 1.749 ± 0.075
4.474AlaAsn: 4.474 ± 0.118
1.697AlaPro: 1.697 ± 0.06
1.846AlaGln: 1.846 ± 0.068
2.255AlaArg: 2.255 ± 0.071
3.668AlaSer: 3.668 ± 0.103
3.092AlaThr: 3.092 ± 0.09
4.536AlaVal: 4.536 ± 0.118
0.449AlaTrp: 0.449 ± 0.032
2.258AlaTyr: 2.258 ± 0.074
0.0AlaXaa: 0.0 ± 0.0
Cys
0.92CysAla: 0.92 ± 0.051
0.145CysCys: 0.145 ± 0.018
0.885CysAsp: 0.885 ± 0.047
1.219CysGlu: 1.219 ± 0.06
0.656CysPhe: 0.656 ± 0.039
1.09CysGly: 1.09 ± 0.054
0.224CysHis: 0.224 ± 0.029
0.964CysIle: 0.964 ± 0.047
0.97CysLys: 0.97 ± 0.045
0.795CysLeu: 0.795 ± 0.044
0.262CysMet: 0.262 ± 0.021
0.457CysAsn: 0.457 ± 0.028
0.374CysPro: 0.374 ± 0.032
0.195CysGln: 0.195 ± 0.018
0.297CysArg: 0.297 ± 0.025
0.677CysSer: 0.677 ± 0.04
0.359CysThr: 0.359 ± 0.029
0.987CysVal: 0.987 ± 0.047
0.071CysTrp: 0.071 ± 0.01
0.397CysTyr: 0.397 ± 0.03
0.0CysXaa: 0.0 ± 0.0
Asp
3.396AspAla: 3.396 ± 0.105
0.544AspCys: 0.544 ± 0.035
3.597AspAsp: 3.597 ± 0.119
6.206AspGlu: 6.206 ± 0.148
4.222AspPhe: 4.222 ± 0.115
3.377AspGly: 3.377 ± 0.122
0.461AspHis: 0.461 ± 0.031
5.46AspIle: 5.46 ± 0.118
5.851AspLys: 5.851 ± 0.142
4.962AspLeu: 4.962 ± 0.105
1.18AspMet: 1.18 ± 0.045
2.895AspAsn: 2.895 ± 0.099
1.269AspPro: 1.269 ± 0.056
0.754AspGln: 0.754 ± 0.039
1.578AspArg: 1.578 ± 0.058
2.775AspSer: 2.775 ± 0.09
2.488AspThr: 2.488 ± 0.117
2.822AspVal: 2.822 ± 0.077
0.312AspTrp: 0.312 ± 0.025
2.199AspTyr: 2.199 ± 0.071
0.0AspXaa: 0.0 ± 0.0
Glu
3.855GluAla: 3.855 ± 0.105
0.719GluCys: 0.719 ± 0.037
2.343GluAsp: 2.343 ± 0.08
2.899GluGlu: 2.899 ± 0.111
4.366GluPhe: 4.366 ± 0.102
2.195GluGly: 2.195 ± 0.067
0.816GluHis: 0.816 ± 0.045
9.998GluIle: 9.998 ± 0.223
7.134GluLys: 7.134 ± 0.149
6.322GluLeu: 6.322 ± 0.141
1.599GluMet: 1.599 ± 0.059
7.169GluAsn: 7.169 ± 0.161
1.541GluPro: 1.541 ± 0.059
1.686GluGln: 1.686 ± 0.062
2.237GluArg: 2.237 ± 0.074
2.827GluSer: 2.827 ± 0.084
2.476GluThr: 2.476 ± 0.073
3.157GluVal: 3.157 ± 0.085
0.378GluTrp: 0.378 ± 0.034
2.079GluTyr: 2.079 ± 0.069
0.0GluXaa: 0.0 ± 0.0
Phe
4.21PheAla: 4.21 ± 0.11
1.111PheCys: 1.111 ± 0.055
4.156PheAsp: 4.156 ± 0.103
3.979PheGlu: 3.979 ± 0.109
3.705PhePhe: 3.705 ± 0.127
4.432PheGly: 4.432 ± 0.113
0.69PheHis: 0.69 ± 0.037
5.62PheIle: 5.62 ± 0.131
5.585PheLys: 5.585 ± 0.132
6.222PheLeu: 6.222 ± 0.161
1.56PheMet: 1.56 ± 0.064
3.3PheAsn: 3.3 ± 0.096
1.209PhePro: 1.209 ± 0.05
1.001PheGln: 1.001 ± 0.048
1.697PheArg: 1.697 ± 0.054
4.629PheSer: 4.629 ± 0.106
2.565PheThr: 2.565 ± 0.093
3.67PheVal: 3.67 ± 0.109
0.565PheTrp: 0.565 ± 0.036
2.735PheTyr: 2.735 ± 0.097
0.0PheXaa: 0.0 ± 0.0
Gly
4.58GlyAla: 4.58 ± 0.119
0.71GlyCys: 0.71 ± 0.044
3.365GlyAsp: 3.365 ± 0.122
4.494GlyGlu: 4.494 ± 0.112
3.844GlyPhe: 3.844 ± 0.09
4.326GlyGly: 4.326 ± 0.152
0.891GlyHis: 0.891 ± 0.047
5.973GlyIle: 5.973 ± 0.119
5.167GlyLys: 5.167 ± 0.114
4.872GlyLeu: 4.872 ± 0.112
1.344GlyMet: 1.344 ± 0.052
3.169GlyAsn: 3.169 ± 0.131
0.783GlyPro: 0.783 ± 0.049
1.126GlyGln: 1.126 ± 0.055
1.886GlyArg: 1.886 ± 0.068
3.618GlySer: 3.618 ± 0.099
2.606GlyThr: 2.606 ± 0.088
4.291GlyVal: 4.291 ± 0.109
0.436GlyTrp: 0.436 ± 0.035
2.415GlyTyr: 2.415 ± 0.079
0.0GlyXaa: 0.0 ± 0.0
His
0.93HisAla: 0.93 ± 0.042
0.162HisCys: 0.162 ± 0.02
0.663HisAsp: 0.663 ± 0.035
0.787HisGlu: 0.787 ± 0.04
0.951HisPhe: 0.951 ± 0.048
0.943HisGly: 0.943 ± 0.045
0.274HisHis: 0.274 ± 0.032
1.277HisIle: 1.277 ± 0.048
1.203HisLys: 1.203 ± 0.055
1.217HisLeu: 1.217 ± 0.053
0.293HisMet: 0.293 ± 0.024
0.675HisAsn: 0.675 ± 0.034
0.594HisPro: 0.594 ± 0.039
0.305HisGln: 0.305 ± 0.026
0.436HisArg: 0.436 ± 0.033
0.862HisSer: 0.862 ± 0.048
0.714HisThr: 0.714 ± 0.038
0.496HisVal: 0.496 ± 0.032
0.089HisTrp: 0.089 ± 0.016
0.552HisTyr: 0.552 ± 0.037
0.0HisXaa: 0.0 ± 0.0
Ile
6.679IleAla: 6.679 ± 0.124
1.585IleCys: 1.585 ± 0.061
5.547IleAsp: 5.547 ± 0.118
5.491IleGlu: 5.491 ± 0.134
6.26IlePhe: 6.26 ± 0.15
5.423IleGly: 5.423 ± 0.111
1.07IleHis: 1.07 ± 0.052
7.57IleIle: 7.57 ± 0.158
8.964IleLys: 8.964 ± 0.145
10.773IleLeu: 10.773 ± 0.203
1.78IleMet: 1.78 ± 0.067
5.913IleAsn: 5.913 ± 0.145
2.646IlePro: 2.646 ± 0.084
1.697IleGln: 1.697 ± 0.063
2.501IleArg: 2.501 ± 0.078
8.069IleSer: 8.069 ± 0.147
4.411IleThr: 4.411 ± 0.094
5.009IleVal: 5.009 ± 0.099
0.546IleTrp: 0.546 ± 0.034
3.878IleTyr: 3.878 ± 0.103
0.0IleXaa: 0.0 ± 0.0
Lys
5.861LysAla: 5.861 ± 0.116
0.887LysCys: 0.887 ± 0.051
6.193LysAsp: 6.193 ± 0.148
6.791LysGlu: 6.791 ± 0.137
6.806LysPhe: 6.806 ± 0.151
4.307LysGly: 4.307 ± 0.125
1.049LysHis: 1.049 ± 0.048
11.743LysIle: 11.743 ± 0.203
9.435LysLys: 9.435 ± 0.187
6.791LysLeu: 6.791 ± 0.146
2.669LysMet: 2.669 ± 0.075
9.601LysAsn: 9.601 ± 0.193
2.287LysPro: 2.287 ± 0.068
2.258LysGln: 2.258 ± 0.078
2.93LysArg: 2.93 ± 0.095
5.938LysSer: 5.938 ± 0.114
4.582LysThr: 4.582 ± 0.103
4.141LysVal: 4.141 ± 0.124
0.503LysTrp: 0.503 ± 0.033
3.144LysTyr: 3.144 ± 0.098
0.0LysXaa: 0.0 ± 0.0
Leu
6.654LeuAla: 6.654 ± 0.125
1.203LeuCys: 1.203 ± 0.057
4.789LeuAsp: 4.789 ± 0.107
5.502LeuGlu: 5.502 ± 0.11
4.997LeuPhe: 4.997 ± 0.119
5.749LeuGly: 5.749 ± 0.113
1.298LeuHis: 1.298 ± 0.049
8.085LeuIle: 8.085 ± 0.162
10.451LeuLys: 10.451 ± 0.18
7.196LeuLeu: 7.196 ± 0.133
1.963LeuMet: 1.963 ± 0.066
7.379LeuAsn: 7.379 ± 0.163
2.984LeuPro: 2.984 ± 0.083
2.706LeuGln: 2.706 ± 0.071
3.169LeuArg: 3.169 ± 0.093
6.617LeuSer: 6.617 ± 0.134
3.911LeuThr: 3.911 ± 0.096
4.206LeuVal: 4.206 ± 0.107
0.544LeuTrp: 0.544 ± 0.039
2.81LeuTyr: 2.81 ± 0.087
0.0LeuXaa: 0.0 ± 0.0
Met
1.547MetAla: 1.547 ± 0.061
0.251MetCys: 0.251 ± 0.024
1.124MetAsp: 1.124 ± 0.049
1.088MetGlu: 1.088 ± 0.05
1.076MetPhe: 1.076 ± 0.055
1.286MetGly: 1.286 ± 0.048
0.384MetHis: 0.384 ± 0.031
2.098MetIle: 2.098 ± 0.068
2.332MetLys: 2.332 ± 0.069
2.093MetLeu: 2.093 ± 0.076
0.482MetMet: 0.482 ± 0.032
1.184MetAsn: 1.184 ± 0.052
0.96MetPro: 0.96 ± 0.049
1.065MetGln: 1.065 ± 0.043
0.914MetArg: 0.914 ± 0.047
1.666MetSer: 1.666 ± 0.06
0.8MetThr: 0.8 ± 0.039
1.113MetVal: 1.113 ± 0.052
0.137MetTrp: 0.137 ± 0.017
0.557MetTyr: 0.557 ± 0.035
0.0MetXaa: 0.0 ± 0.0
Asn
4.744AsnAla: 4.744 ± 0.117
0.623AsnCys: 0.623 ± 0.04
4.139AsnAsp: 4.139 ± 0.145
5.72AsnGlu: 5.72 ± 0.144
5.981AsnPhe: 5.981 ± 0.153
4.536AsnGly: 4.536 ± 0.131
0.845AsnHis: 0.845 ± 0.045
5.716AsnIle: 5.716 ± 0.131
5.51AsnLys: 5.51 ± 0.15
7.614AsnLeu: 7.614 ± 0.145
1.117AsnMet: 1.117 ± 0.046
3.439AsnAsn: 3.439 ± 0.16
2.073AsnPro: 2.073 ± 0.057
1.583AsnGln: 1.583 ± 0.066
2.1AsnArg: 2.1 ± 0.079
4.685AsnSer: 4.685 ± 0.128
2.744AsnThr: 2.744 ± 0.104
3.475AsnVal: 3.475 ± 0.082
0.363AsnTrp: 0.363 ± 0.03
2.417AsnTyr: 2.417 ± 0.078
0.0AsnXaa: 0.0 ± 0.0
Pro
1.531ProAla: 1.531 ± 0.068
0.307ProCys: 0.307 ± 0.027
1.414ProAsp: 1.414 ± 0.048
1.662ProGlu: 1.662 ± 0.063
1.799ProPhe: 1.799 ± 0.077
1.29ProGly: 1.29 ± 0.056
0.434ProHis: 0.434 ± 0.026
2.123ProIle: 2.123 ± 0.068
2.698ProLys: 2.698 ± 0.08
2.644ProLeu: 2.644 ± 0.085
0.469ProMet: 0.469 ± 0.037
1.977ProAsn: 1.977 ± 0.076
0.631ProPro: 0.631 ± 0.037
0.804ProGln: 0.804 ± 0.043
0.773ProArg: 0.773 ± 0.043
1.529ProSer: 1.529 ± 0.063
1.356ProThr: 1.356 ± 0.049
1.817ProVal: 1.817 ± 0.07
0.191ProTrp: 0.191 ± 0.02
1.173ProTyr: 1.173 ± 0.045
0.0ProXaa: 0.0 ± 0.0
Gln
1.23GlnAla: 1.23 ± 0.054
0.172GlnCys: 0.172 ± 0.017
1.084GlnAsp: 1.084 ± 0.043
1.25GlnGlu: 1.25 ± 0.056
0.847GlnPhe: 0.847 ± 0.038
1.111GlnGly: 1.111 ± 0.055
0.235GlnHis: 0.235 ± 0.022
3.167GlnIle: 3.167 ± 0.082
3.14GlnLys: 3.14 ± 0.087
1.329GlnLeu: 1.329 ± 0.054
0.654GlnMet: 0.654 ± 0.036
3.487GlnAsn: 3.487 ± 0.109
0.507GlnPro: 0.507 ± 0.033
0.44GlnGln: 0.44 ± 0.029
0.69GlnArg: 0.69 ± 0.043
1.599GlnSer: 1.599 ± 0.063
1.362GlnThr: 1.362 ± 0.051
1.08GlnVal: 1.08 ± 0.046
0.118GlnTrp: 0.118 ± 0.016
0.521GlnTyr: 0.521 ± 0.031
0.0GlnXaa: 0.0 ± 0.0
Arg
2.349ArgAla: 2.349 ± 0.07
0.295ArgCys: 0.295 ± 0.025
1.769ArgAsp: 1.769 ± 0.062
2.378ArgGlu: 2.378 ± 0.076
1.796ArgPhe: 1.796 ± 0.062
1.707ArgGly: 1.707 ± 0.058
0.525ArgHis: 0.525 ± 0.035
2.748ArgIle: 2.748 ± 0.075
2.781ArgLys: 2.781 ± 0.086
2.914ArgLeu: 2.914 ± 0.084
0.631ArgMet: 0.631 ± 0.035
2.077ArgAsn: 2.077 ± 0.073
0.868ArgPro: 0.868 ± 0.044
0.887ArgGln: 0.887 ± 0.046
1.178ArgArg: 1.178 ± 0.058
1.63ArgSer: 1.63 ± 0.056
1.263ArgThr: 1.263 ± 0.051
1.975ArgVal: 1.975 ± 0.07
0.191ArgTrp: 0.191 ± 0.022
1.203ArgTyr: 1.203 ± 0.046
0.0ArgXaa: 0.0 ± 0.0
Ser
4.565SerAla: 4.565 ± 0.122
0.673SerCys: 0.673 ± 0.038
3.77SerAsp: 3.77 ± 0.088
4.116SerGlu: 4.116 ± 0.11
3.641SerPhe: 3.641 ± 0.096
4.731SerGly: 4.731 ± 0.109
1.02SerHis: 1.02 ± 0.048
4.92SerIle: 4.92 ± 0.112
5.998SerLys: 5.998 ± 0.109
5.988SerLeu: 5.988 ± 0.128
1.352SerMet: 1.352 ± 0.057
3.832SerAsn: 3.832 ± 0.133
1.666SerPro: 1.666 ± 0.067
1.975SerGln: 1.975 ± 0.064
2.025SerArg: 2.025 ± 0.062
4.183SerSer: 4.183 ± 0.115
2.525SerThr: 2.525 ± 0.103
4.253SerVal: 4.253 ± 0.119
0.478SerTrp: 0.478 ± 0.031
2.129SerTyr: 2.129 ± 0.084
0.0SerXaa: 0.0 ± 0.0
Thr
3.101ThrAla: 3.101 ± 0.074
0.399ThrCys: 0.399 ± 0.032
2.403ThrAsp: 2.403 ± 0.076
2.181ThrGlu: 2.181 ± 0.066
2.147ThrPhe: 2.147 ± 0.063
2.918ThrGly: 2.918 ± 0.096
0.82ThrHis: 0.82 ± 0.052
3.873ThrIle: 3.873 ± 0.147
4.04ThrLys: 4.04 ± 0.114
4.434ThrLeu: 4.434 ± 0.098
0.839ThrMet: 0.839 ± 0.043
3.014ThrAsn: 3.014 ± 0.108
1.867ThrPro: 1.867 ± 0.061
1.4ThrGln: 1.4 ± 0.058
1.271ThrArg: 1.271 ± 0.052
2.538ThrSer: 2.538 ± 0.081
2.091ThrThr: 2.091 ± 0.081
1.969ThrVal: 1.969 ± 0.071
0.241ThrTrp: 0.241 ± 0.023
1.659ThrTyr: 1.659 ± 0.072
0.0ThrXaa: 0.0 ± 0.0
Val
4.096ValAla: 4.096 ± 0.116
0.885ValCys: 0.885 ± 0.047
2.93ValAsp: 2.93 ± 0.084
3.302ValGlu: 3.302 ± 0.093
3.159ValPhe: 3.159 ± 0.091
3.647ValGly: 3.647 ± 0.111
0.646ValHis: 0.646 ± 0.04
4.962ValIle: 4.962 ± 0.101
5.14ValLys: 5.14 ± 0.116
5.134ValLeu: 5.134 ± 0.099
1.279ValMet: 1.279 ± 0.055
2.976ValAsn: 2.976 ± 0.085
1.539ValPro: 1.539 ± 0.067
1.209ValGln: 1.209 ± 0.052
1.815ValArg: 1.815 ± 0.06
3.89ValSer: 3.89 ± 0.088
2.085ValThr: 2.085 ± 0.08
3.481ValVal: 3.481 ± 0.104
0.357ValTrp: 0.357 ± 0.027
1.836ValTyr: 1.836 ± 0.059
0.0ValXaa: 0.0 ± 0.0
Trp
0.422TrpAla: 0.422 ± 0.031
0.077TrpCys: 0.077 ± 0.014
0.347TrpAsp: 0.347 ± 0.025
0.266TrpGlu: 0.266 ± 0.023
0.386TrpPhe: 0.386 ± 0.03
0.463TrpGly: 0.463 ± 0.032
0.158TrpHis: 0.158 ± 0.018
0.609TrpIle: 0.609 ± 0.033
0.413TrpLys: 0.413 ± 0.028
0.714TrpLeu: 0.714 ± 0.044
0.195TrpMet: 0.195 ± 0.023
0.309TrpAsn: 0.309 ± 0.024
0.106TrpPro: 0.106 ± 0.016
0.314TrpGln: 0.314 ± 0.025
0.28TrpArg: 0.28 ± 0.03
0.295TrpSer: 0.295 ± 0.022
0.208TrpThr: 0.208 ± 0.021
0.339TrpVal: 0.339 ± 0.028
0.1TrpTrp: 0.1 ± 0.015
0.253TrpTyr: 0.253 ± 0.024
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.488TyrAla: 2.488 ± 0.078
0.413TyrCys: 0.413 ± 0.03
2.424TyrAsp: 2.424 ± 0.081
2.893TyrGlu: 2.893 ± 0.08
2.482TyrPhe: 2.482 ± 0.076
2.145TyrGly: 2.145 ± 0.079
0.53TyrHis: 0.53 ± 0.036
2.808TyrIle: 2.808 ± 0.081
3.674TyrLys: 3.674 ± 0.093
3.149TyrLeu: 3.149 ± 0.091
0.737TyrMet: 0.737 ± 0.04
2.096TyrAsn: 2.096 ± 0.065
1.022TyrPro: 1.022 ± 0.045
0.775TyrGln: 0.775 ± 0.038
1.134TyrArg: 1.134 ± 0.052
2.145TyrSer: 2.145 ± 0.072
1.566TyrThr: 1.566 ± 0.058
1.551TyrVal: 1.551 ± 0.069
0.185TyrTrp: 0.185 ± 0.022
1.346TyrTyr: 1.346 ± 0.067
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1687 proteins (481493 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski