Amino acid dipepetide frequency for Spirosoma sordidisoli

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.712AlaAla: 7.712 ± 0.076	0.71AlaCys: 0.71 ± 0.022	6.003AlaAsp: 6.003 ± 0.052	4.858AlaGlu: 4.858 ± 0.056	3.636AlaPhe: 3.636 ± 0.05	7.377AlaGly: 7.377 ± 0.071	1.426AlaHis: 1.426 ± 0.031	4.706AlaIle: 4.706 ± 0.048	3.253AlaLys: 3.253 ± 0.046	8.943AlaLeu: 8.943 ± 0.091	1.868AlaMet: 1.868 ± 0.03	3.639AlaAsn: 3.639 ± 0.055	3.689AlaPro: 3.689 ± 0.058	4.128AlaGln: 4.128 ± 0.044	5.064AlaArg: 5.064 ± 0.057	5.45AlaSer: 5.45 ± 0.069	5.678AlaThr: 5.678 ± 0.071	6.208AlaVal: 6.208 ± 0.063	1.029AlaTrp: 1.029 ± 0.026	3.261AlaTyr: 3.261 ± 0.041	0.0AlaXaa: 0.0 ± 0.0
Cys	0.541CysAla: 0.541 ± 0.019	0.102CysCys: 0.102 ± 0.008	0.365CysAsp: 0.365 ± 0.018	0.351CysGlu: 0.351 ± 0.016	0.335CysPhe: 0.335 ± 0.013	0.544CysGly: 0.544 ± 0.017	0.19CysHis: 0.19 ± 0.01	0.391CysIle: 0.391 ± 0.014	0.25CysLys: 0.25 ± 0.012	0.823CysLeu: 0.823 ± 0.022	0.136CysMet: 0.136 ± 0.008	0.25CysAsn: 0.25 ± 0.013	0.382CysPro: 0.382 ± 0.019	0.393CysGln: 0.393 ± 0.014	0.468CysArg: 0.468 ± 0.016	0.469CysSer: 0.469 ± 0.015	0.464CysThr: 0.464 ± 0.018	0.48CysVal: 0.48 ± 0.018	0.108CysTrp: 0.108 ± 0.007	0.279CysTyr: 0.279 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	4.809AspAla: 4.809 ± 0.058	0.394AspCys: 0.394 ± 0.017	2.755AspAsp: 2.755 ± 0.036	3.365AspGlu: 3.365 ± 0.046	2.522AspPhe: 2.522 ± 0.036	4.204AspGly: 4.204 ± 0.067	0.943AspHis: 0.943 ± 0.024	2.931AspIle: 2.931 ± 0.036	2.489AspLys: 2.489 ± 0.047	5.305AspLeu: 5.305 ± 0.059	1.1AspMet: 1.1 ± 0.025	2.212AspAsn: 2.212 ± 0.036	2.761AspPro: 2.761 ± 0.038	2.532AspGln: 2.532 ± 0.036	3.545AspArg: 3.545 ± 0.053	2.837AspSer: 2.837 ± 0.043	2.936AspThr: 2.936 ± 0.043	3.749AspVal: 3.749 ± 0.043	0.976AspTrp: 0.976 ± 0.021	2.37AspTyr: 2.37 ± 0.035	0.0AspXaa: 0.0 ± 0.0
Glu	4.715GluAla: 4.715 ± 0.057	0.255GluCys: 0.255 ± 0.012	1.911GluAsp: 1.911 ± 0.033	2.591GluGlu: 2.591 ± 0.042	1.89GluPhe: 1.89 ± 0.03	3.163GluGly: 3.163 ± 0.048	0.904GluHis: 0.904 ± 0.024	2.664GluIle: 2.664 ± 0.04	2.764GluLys: 2.764 ± 0.047	5.44GluLeu: 5.44 ± 0.06	1.082GluMet: 1.082 ± 0.022	2.042GluAsn: 2.042 ± 0.031	2.228GluPro: 2.228 ± 0.04	2.841GluGln: 2.841 ± 0.043	3.408GluArg: 3.408 ± 0.048	2.661GluSer: 2.661 ± 0.035	3.182GluThr: 3.182 ± 0.039	3.541GluVal: 3.541 ± 0.047	0.613GluTrp: 0.613 ± 0.019	1.641GluTyr: 1.641 ± 0.027	0.0GluXaa: 0.0 ± 0.0
Phe	3.382PheAla: 3.382 ± 0.039	0.398PheCys: 0.398 ± 0.015	2.778PheAsp: 2.778 ± 0.045	2.034PheGlu: 2.034 ± 0.031	2.006PhePhe: 2.006 ± 0.04	3.462PheGly: 3.462 ± 0.044	0.649PheHis: 0.649 ± 0.018	2.231PheIle: 2.231 ± 0.027	1.482PheLys: 1.482 ± 0.033	3.874PheLeu: 3.874 ± 0.05	0.945PheMet: 0.945 ± 0.023	1.908PheAsn: 1.908 ± 0.029	1.779PhePro: 1.779 ± 0.029	1.527PheGln: 1.527 ± 0.025	2.772PheArg: 2.772 ± 0.044	3.047PheSer: 3.047 ± 0.038	2.943PheThr: 2.943 ± 0.038	3.064PheVal: 3.064 ± 0.039	0.631PheTrp: 0.631 ± 0.018	1.64PheTyr: 1.64 ± 0.026	0.0PheXaa: 0.0 ± 0.0
Gly	5.432GlyAla: 5.432 ± 0.063	0.706GlyCys: 0.706 ± 0.024	3.432GlyAsp: 3.432 ± 0.05	3.203GlyGlu: 3.203 ± 0.041	3.431GlyPhe: 3.431 ± 0.042	5.529GlyGly: 5.529 ± 0.069	1.306GlyHis: 1.306 ± 0.026	4.324GlyIle: 4.324 ± 0.046	3.78GlyLys: 3.78 ± 0.052	7.707GlyLeu: 7.707 ± 0.078	1.624GlyMet: 1.624 ± 0.029	3.231GlyAsn: 3.231 ± 0.049	2.542GlyPro: 2.542 ± 0.042	3.902GlyGln: 3.902 ± 0.053	4.309GlyArg: 4.309 ± 0.053	4.813GlySer: 4.813 ± 0.068	4.882GlyThr: 4.882 ± 0.073	5.132GlyVal: 5.132 ± 0.05	1.266GlyTrp: 1.266 ± 0.026	3.101GlyTyr: 3.101 ± 0.035	0.0GlyXaa: 0.0 ± 0.0
His	1.268HisAla: 1.268 ± 0.025	0.178HisCys: 0.178 ± 0.01	0.923HisAsp: 0.923 ± 0.02	0.941HisGlu: 0.941 ± 0.022	0.895HisPhe: 0.895 ± 0.021	1.129HisGly: 1.129 ± 0.026	0.5HisHis: 0.5 ± 0.018	1.047HisIle: 1.047 ± 0.024	0.683HisLys: 0.683 ± 0.018	1.819HisLeu: 1.819 ± 0.036	0.328HisMet: 0.328 ± 0.013	0.662HisAsn: 0.662 ± 0.018	1.165HisPro: 1.165 ± 0.025	0.851HisGln: 0.851 ± 0.024	1.158HisArg: 1.158 ± 0.023	0.91HisSer: 0.91 ± 0.024	1.157HisThr: 1.157 ± 0.024	1.093HisVal: 1.093 ± 0.021	0.312HisTrp: 0.312 ± 0.012	0.805HisTyr: 0.805 ± 0.021	0.0HisXaa: 0.0 ± 0.0
Ile	4.555IleAla: 4.555 ± 0.047	0.476IleCys: 0.476 ± 0.014	3.636IleAsp: 3.636 ± 0.045	3.019IleGlu: 3.019 ± 0.049	1.778IlePhe: 1.778 ± 0.032	4.515IleGly: 4.515 ± 0.056	0.986IleHis: 0.986 ± 0.023	2.683IleIle: 2.683 ± 0.046	2.19IleLys: 2.19 ± 0.037	4.409IleLeu: 4.409 ± 0.052	0.943IleMet: 0.943 ± 0.022	2.708IleAsn: 2.708 ± 0.04	2.689IlePro: 2.689 ± 0.034	2.187IleGln: 2.187 ± 0.032	3.856IleArg: 3.856 ± 0.046	3.39IleSer: 3.39 ± 0.043	3.564IleThr: 3.564 ± 0.043	3.547IleVal: 3.547 ± 0.044	0.655IleTrp: 0.655 ± 0.018	1.759IleTyr: 1.759 ± 0.028	0.0IleXaa: 0.0 ± 0.0
Lys	4.116LysAla: 4.116 ± 0.054	0.175LysCys: 0.175 ± 0.01	2.111LysAsp: 2.111 ± 0.037	2.305LysGlu: 2.305 ± 0.038	1.29LysPhe: 1.29 ± 0.024	3.006LysGly: 3.006 ± 0.045	0.75LysHis: 0.75 ± 0.023	2.188LysIle: 2.188 ± 0.036	2.325LysLys: 2.325 ± 0.046	4.16LysLeu: 4.16 ± 0.044	0.946LysMet: 0.946 ± 0.023	1.982LysAsn: 1.982 ± 0.034	2.7LysPro: 2.7 ± 0.039	2.071LysGln: 2.071 ± 0.036	2.533LysArg: 2.533 ± 0.039	2.252LysSer: 2.252 ± 0.039	3.025LysThr: 3.025 ± 0.039	2.695LysVal: 2.695 ± 0.042	0.471LysTrp: 0.471 ± 0.014	1.382LysTyr: 1.382 ± 0.027	0.0LysXaa: 0.0 ± 0.0
Leu	9.617LeuAla: 9.617 ± 0.085	0.758LeuCys: 0.758 ± 0.019	5.252LeuAsp: 5.252 ± 0.052	4.231LeuGlu: 4.231 ± 0.049	4.489LeuPhe: 4.489 ± 0.052	6.545LeuGly: 6.545 ± 0.066	1.817LeuHis: 1.817 ± 0.031	5.596LeuIle: 5.596 ± 0.059	4.428LeuLys: 4.428 ± 0.049	11.105LeuLeu: 11.105 ± 0.112	2.172LeuMet: 2.172 ± 0.029	4.696LeuAsn: 4.696 ± 0.046	5.36LeuPro: 5.36 ± 0.059	3.711LeuGln: 3.711 ± 0.042	5.992LeuArg: 5.992 ± 0.07	6.972LeuSer: 6.972 ± 0.061	7.851LeuThr: 7.851 ± 0.073	6.764LeuVal: 6.764 ± 0.065	1.068LeuTrp: 1.068 ± 0.025	3.397LeuTyr: 3.397 ± 0.043	0.0LeuXaa: 0.0 ± 0.0
Met	2.132MetAla: 2.132 ± 0.032	0.101MetCys: 0.101 ± 0.007	0.948MetAsp: 0.948 ± 0.025	0.913MetGlu: 0.913 ± 0.02	0.567MetPhe: 0.567 ± 0.017	1.453MetGly: 1.453 ± 0.029	0.405MetHis: 0.405 ± 0.014	1.044MetIle: 1.044 ± 0.023	1.337MetLys: 1.337 ± 0.024	2.056MetLeu: 2.056 ± 0.03	0.497MetMet: 0.497 ± 0.016	1.153MetAsn: 1.153 ± 0.023	1.16MetPro: 1.16 ± 0.023	0.935MetGln: 0.935 ± 0.024	1.179MetArg: 1.179 ± 0.023	1.209MetSer: 1.209 ± 0.026	1.433MetThr: 1.433 ± 0.028	1.229MetVal: 1.229 ± 0.027	0.172MetTrp: 0.172 ± 0.008	0.539MetTyr: 0.539 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	3.739AsnAla: 3.739 ± 0.046	0.288AsnCys: 0.288 ± 0.014	2.305AsnAsp: 2.305 ± 0.043	2.233AsnGlu: 2.233 ± 0.03	1.719AsnPhe: 1.719 ± 0.034	3.675AsnGly: 3.675 ± 0.05	0.779AsnHis: 0.779 ± 0.022	2.043AsnIle: 2.043 ± 0.037	1.656AsnLys: 1.656 ± 0.032	4.14AsnLeu: 4.14 ± 0.045	0.807AsnMet: 0.807 ± 0.018	2.073AsnAsn: 2.073 ± 0.041	2.839AsnPro: 2.839 ± 0.04	2.224AsnGln: 2.224 ± 0.036	3.1AsnArg: 3.1 ± 0.047	2.289AsnSer: 2.289 ± 0.039	2.699AsnThr: 2.699 ± 0.042	2.859AsnVal: 2.859 ± 0.04	0.648AsnTrp: 0.648 ± 0.015	1.805AsnTyr: 1.805 ± 0.034	0.0AsnXaa: 0.0 ± 0.0
Pro	5.725ProAla: 5.725 ± 0.074	0.236ProCys: 0.236 ± 0.011	3.733ProAsp: 3.733 ± 0.049	2.78ProGlu: 2.78 ± 0.041	2.095ProPhe: 2.095 ± 0.033	3.777ProGly: 3.777 ± 0.047	0.794ProHis: 0.794 ± 0.019	2.58ProIle: 2.58 ± 0.034	1.866ProLys: 1.866 ± 0.031	4.291ProLeu: 4.291 ± 0.048	1.012ProMet: 1.012 ± 0.023	2.221ProAsn: 2.221 ± 0.037	1.73ProPro: 1.73 ± 0.034	1.725ProGln: 1.725 ± 0.026	2.038ProArg: 2.038 ± 0.033	2.581ProSer: 2.581 ± 0.039	3.395ProThr: 3.395 ± 0.049	4.189ProVal: 4.189 ± 0.052	0.492ProTrp: 0.492 ± 0.016	1.732ProTyr: 1.732 ± 0.028	0.0ProXaa: 0.0 ± 0.0
Gln	4.358GlnAla: 4.358 ± 0.053	0.229GlnCys: 0.229 ± 0.01	1.714GlnAsp: 1.714 ± 0.03	2.053GlnGlu: 2.053 ± 0.036	1.909GlnPhe: 1.909 ± 0.03	2.524GlnGly: 2.524 ± 0.038	0.922GlnHis: 0.922 ± 0.023	2.422GlnIle: 2.422 ± 0.04	2.089GlnLys: 2.089 ± 0.036	5.254GlnLeu: 5.254 ± 0.057	0.928GlnMet: 0.928 ± 0.021	1.887GlnAsn: 1.887 ± 0.032	2.981GlnPro: 2.981 ± 0.04	2.942GlnGln: 2.942 ± 0.047	2.85GlnArg: 2.85 ± 0.038	2.532GlnSer: 2.532 ± 0.037	3.355GlnThr: 3.355 ± 0.044	3.001GlnVal: 3.001 ± 0.037	0.551GlnTrp: 0.551 ± 0.019	1.751GlnTyr: 1.751 ± 0.027	0.0GlnXaa: 0.0 ± 0.0
Arg	4.616ArgAla: 4.616 ± 0.052	0.366ArgCys: 0.366 ± 0.013	2.943ArgAsp: 2.943 ± 0.04	2.972ArgGlu: 2.972 ± 0.04	2.972ArgPhe: 2.972 ± 0.041	3.265ArgGly: 3.265 ± 0.046	1.161ArgHis: 1.161 ± 0.023	3.684ArgIle: 3.684 ± 0.041	2.584ArgLys: 2.584 ± 0.037	6.681ArgLeu: 6.681 ± 0.075	1.4ArgMet: 1.4 ± 0.028	2.645ArgAsn: 2.645 ± 0.039	2.954ArgPro: 2.954 ± 0.043	3.772ArgGln: 3.772 ± 0.052	3.423ArgArg: 3.423 ± 0.053	3.474ArgSer: 3.474 ± 0.038	3.681ArgThr: 3.681 ± 0.041	4.19ArgVal: 4.19 ± 0.042	0.97ArgTrp: 0.97 ± 0.022	2.635ArgTyr: 2.635 ± 0.036	0.0ArgXaa: 0.0 ± 0.0
Ser	5.498SerAla: 5.498 ± 0.063	0.493SerCys: 0.493 ± 0.017	3.021SerAsp: 3.021 ± 0.036	2.655SerGlu: 2.655 ± 0.038	2.969SerPhe: 2.969 ± 0.039	4.993SerGly: 4.993 ± 0.068	0.991SerHis: 0.991 ± 0.022	3.2SerIle: 3.2 ± 0.045	2.102SerLys: 2.102 ± 0.034	6.653SerLeu: 6.653 ± 0.066	1.184SerMet: 1.184 ± 0.024	2.23SerAsn: 2.23 ± 0.038	3.003SerPro: 3.003 ± 0.041	2.575SerGln: 2.575 ± 0.04	3.462SerArg: 3.462 ± 0.049	3.694SerSer: 3.694 ± 0.047	3.797SerThr: 3.797 ± 0.06	4.731SerVal: 4.731 ± 0.057	0.852SerTrp: 0.852 ± 0.019	2.314SerTyr: 2.314 ± 0.034	0.0SerXaa: 0.0 ± 0.0
Thr	5.982ThrAla: 5.982 ± 0.082	0.382ThrCys: 0.382 ± 0.016	4.229ThrAsp: 4.229 ± 0.048	3.056ThrGlu: 3.056 ± 0.043	2.822ThrPhe: 2.822 ± 0.04	5.707ThrGly: 5.707 ± 0.07	1.123ThrHis: 1.123 ± 0.025	3.776ThrIle: 3.776 ± 0.042	2.291ThrLys: 2.291 ± 0.034	6.869ThrLeu: 6.869 ± 0.07	1.096ThrMet: 1.096 ± 0.024	2.949ThrAsn: 2.949 ± 0.046	3.578ThrPro: 3.578 ± 0.05	2.419ThrGln: 2.419 ± 0.038	3.315ThrArg: 3.315 ± 0.044	3.797ThrSer: 3.797 ± 0.058	4.446ThrThr: 4.446 ± 0.078	5.018ThrVal: 5.018 ± 0.074	0.732ThrTrp: 0.732 ± 0.019	2.699ThrTyr: 2.699 ± 0.037	0.0ThrXaa: 0.0 ± 0.0
Val	6.382ValAla: 6.382 ± 0.066	0.642ValCys: 0.642 ± 0.021	3.823ValAsp: 3.823 ± 0.042	3.452ValGlu: 3.452 ± 0.04	2.906ValPhe: 2.906 ± 0.04	5.114ValGly: 5.114 ± 0.053	1.125ValHis: 1.125 ± 0.023	3.673ValIle: 3.673 ± 0.048	2.83ValLys: 2.83 ± 0.039	6.94ValLeu: 6.94 ± 0.06	1.42ValMet: 1.42 ± 0.024	3.116ValAsn: 3.116 ± 0.04	3.259ValPro: 3.259 ± 0.046	2.74ValGln: 2.74 ± 0.036	4.438ValArg: 4.438 ± 0.05	5.043ValSer: 5.043 ± 0.063	4.549ValThr: 4.549 ± 0.063	5.45ValVal: 5.45 ± 0.061	0.952ValTrp: 0.952 ± 0.022	2.443ValTyr: 2.443 ± 0.031	0.0ValXaa: 0.0 ± 0.0
Trp	1.006TrpAla: 1.006 ± 0.023	0.103TrpCys: 0.103 ± 0.007	0.611TrpAsp: 0.611 ± 0.018	0.604TrpGlu: 0.604 ± 0.016	0.591TrpPhe: 0.591 ± 0.017	0.898TrpGly: 0.898 ± 0.025	0.32TrpHis: 0.32 ± 0.014	0.635TrpIle: 0.635 ± 0.018	0.564TrpLys: 0.564 ± 0.018	1.707TrpLeu: 1.707 ± 0.035	0.312TrpMet: 0.312 ± 0.013	0.59TrpAsn: 0.59 ± 0.017	0.497TrpPro: 0.497 ± 0.016	0.851TrpGln: 0.851 ± 0.023	0.817TrpArg: 0.817 ± 0.022	0.774TrpSer: 0.774 ± 0.02	0.805TrpThr: 0.805 ± 0.021	0.874TrpVal: 0.874 ± 0.022	0.229TrpTrp: 0.229 ± 0.012	0.494TrpTyr: 0.494 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.053TyrAla: 3.053 ± 0.039	0.331TyrCys: 0.331 ± 0.014	2.241TyrAsp: 2.241 ± 0.041	1.918TyrGlu: 1.918 ± 0.035	1.731TyrPhe: 1.731 ± 0.028	2.772TyrGly: 2.772 ± 0.035	0.734TyrHis: 0.734 ± 0.019	1.727TyrIle: 1.727 ± 0.034	1.518TyrLys: 1.518 ± 0.029	3.643TyrLeu: 3.643 ± 0.043	0.661TyrMet: 0.661 ± 0.017	1.727TyrAsn: 1.727 ± 0.033	1.694TyrPro: 1.694 ± 0.028	1.931TyrGln: 1.931 ± 0.031	2.661TyrArg: 2.661 ± 0.037	2.221TyrSer: 2.221 ± 0.033	2.446TyrThr: 2.446 ± 0.043	2.48TyrVal: 2.48 ± 0.038	0.556TyrTrp: 0.556 ± 0.018	1.551TyrTyr: 1.551 ± 0.026	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 6027 proteins (2154023 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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