Amino acid dipepetide frequency for Bifidobacterium angulatum DSM 20098 = JCM 7096

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	12.879AlaAla: 12.879 ± 0.217	1.214AlaCys: 1.214 ± 0.05	7.064AlaAsp: 7.064 ± 0.131	6.204AlaGlu: 6.204 ± 0.118	3.541AlaPhe: 3.541 ± 0.091	8.643AlaGly: 8.643 ± 0.146	2.236AlaHis: 2.236 ± 0.068	5.878AlaIle: 5.878 ± 0.106	5.162AlaLys: 5.162 ± 0.105	9.954AlaLeu: 9.954 ± 0.174	3.349AlaMet: 3.349 ± 0.084	3.62AlaAsn: 3.62 ± 0.09	3.724AlaPro: 3.724 ± 0.112	4.391AlaGln: 4.391 ± 0.114	5.821AlaArg: 5.821 ± 0.112	6.613AlaSer: 6.613 ± 0.131	5.958AlaThr: 5.958 ± 0.117	8.682AlaVal: 8.682 ± 0.163	1.483AlaTrp: 1.483 ± 0.052	2.726AlaTyr: 2.726 ± 0.071	0.0AlaXaa: 0.0 ± 0.0
Cys	1.178CysAla: 1.178 ± 0.046	0.15CysCys: 0.15 ± 0.016	0.64CysAsp: 0.64 ± 0.032	0.541CysGlu: 0.541 ± 0.035	0.368CysPhe: 0.368 ± 0.027	1.095CysGly: 1.095 ± 0.047	0.238CysHis: 0.238 ± 0.02	0.506CysIle: 0.506 ± 0.03	0.31CysLys: 0.31 ± 0.025	0.853CysLeu: 0.853 ± 0.042	0.284CysMet: 0.284 ± 0.022	0.303CysAsn: 0.303 ± 0.023	0.46CysPro: 0.46 ± 0.032	0.243CysGln: 0.243 ± 0.022	0.582CysArg: 0.582 ± 0.032	0.652CysSer: 0.652 ± 0.035	0.616CysThr: 0.616 ± 0.035	0.879CysVal: 0.879 ± 0.041	0.148CysTrp: 0.148 ± 0.013	0.249CysTyr: 0.249 ± 0.022	0.0CysXaa: 0.0 ± 0.0
Asp	6.966AspAla: 6.966 ± 0.128	0.608AspCys: 0.608 ± 0.034	4.349AspAsp: 4.349 ± 0.104	4.757AspGlu: 4.757 ± 0.107	2.297AspPhe: 2.297 ± 0.077	5.668AspGly: 5.668 ± 0.113	1.246AspHis: 1.246 ± 0.046	3.332AspIle: 3.332 ± 0.076	2.469AspLys: 2.469 ± 0.078	5.019AspLeu: 5.019 ± 0.093	1.875AspMet: 1.875 ± 0.061	1.846AspAsn: 1.846 ± 0.062	3.194AspPro: 3.194 ± 0.076	1.778AspGln: 1.778 ± 0.059	3.264AspArg: 3.264 ± 0.078	3.538AspSer: 3.538 ± 0.088	3.191AspThr: 3.191 ± 0.082	4.783AspVal: 4.783 ± 0.102	1.042AspTrp: 1.042 ± 0.047	1.88AspTyr: 1.88 ± 0.066	0.0AspXaa: 0.0 ± 0.0
Glu	6.065GluAla: 6.065 ± 0.114	0.504GluCys: 0.504 ± 0.028	3.124GluAsp: 3.124 ± 0.089	3.458GluGlu: 3.458 ± 0.093	1.844GluPhe: 1.844 ± 0.055	3.889GluGly: 3.889 ± 0.091	1.878GluHis: 1.878 ± 0.062	2.786GluIle: 2.786 ± 0.074	2.249GluLys: 2.249 ± 0.07	5.265GluLeu: 5.265 ± 0.108	1.429GluMet: 1.429 ± 0.047	1.972GluAsn: 1.972 ± 0.057	2.617GluPro: 2.617 ± 0.067	2.784GluGln: 2.784 ± 0.086	4.287GluArg: 4.287 ± 0.106	3.436GluSer: 3.436 ± 0.075	3.317GluThr: 3.317 ± 0.082	3.608GluVal: 3.608 ± 0.083	0.739GluTrp: 0.739 ± 0.036	1.774GluTyr: 1.774 ± 0.062	0.0GluXaa: 0.0 ± 0.0
Phe	4.09PheAla: 4.09 ± 0.095	0.405PheCys: 0.405 ± 0.027	2.648PheAsp: 2.648 ± 0.074	1.818PheGlu: 1.818 ± 0.058	1.216PhePhe: 1.216 ± 0.05	3.228PheGly: 3.228 ± 0.089	0.809PheHis: 0.809 ± 0.042	1.873PheIle: 1.873 ± 0.062	1.212PheLys: 1.212 ± 0.048	2.758PheLeu: 2.758 ± 0.072	0.822PheMet: 0.822 ± 0.04	1.18PheAsn: 1.18 ± 0.044	1.384PhePro: 1.384 ± 0.053	0.952PheGln: 0.952 ± 0.043	1.58PheArg: 1.58 ± 0.057	2.276PheSer: 2.276 ± 0.057	2.292PheThr: 2.292 ± 0.063	2.648PheVal: 2.648 ± 0.072	0.419PheTrp: 0.419 ± 0.03	0.885PheTyr: 0.885 ± 0.041	0.0PheXaa: 0.0 ± 0.0
Gly	7.417GlyAla: 7.417 ± 0.13	0.865GlyCys: 0.865 ± 0.039	4.563GlyAsp: 4.563 ± 0.093	4.8GlyGlu: 4.8 ± 0.107	3.189GlyPhe: 3.189 ± 0.072	5.958GlyGly: 5.958 ± 0.132	1.791GlyHis: 1.791 ± 0.06	4.887GlyIle: 4.887 ± 0.108	4.343GlyLys: 4.343 ± 0.098	6.937GlyLeu: 6.937 ± 0.127	2.421GlyMet: 2.421 ± 0.075	3.029GlyAsn: 3.029 ± 0.082	2.425GlyPro: 2.425 ± 0.063	2.503GlyGln: 2.503 ± 0.071	4.459GlyArg: 4.459 ± 0.099	5.321GlySer: 5.321 ± 0.105	5.28GlyThr: 5.28 ± 0.102	6.359GlyVal: 6.359 ± 0.104	1.226GlyTrp: 1.226 ± 0.049	2.597GlyTyr: 2.597 ± 0.066	0.0GlyXaa: 0.0 ± 0.0
His	2.477HisAla: 2.477 ± 0.061	0.264HisCys: 0.264 ± 0.02	1.59HisAsp: 1.59 ± 0.057	1.289HisGlu: 1.289 ± 0.047	0.63HisPhe: 0.63 ± 0.034	2.076HisGly: 2.076 ± 0.067	0.528HisHis: 0.528 ± 0.031	1.27HisIle: 1.27 ± 0.05	0.664HisLys: 0.664 ± 0.031	1.587HisLeu: 1.587 ± 0.051	0.722HisMet: 0.722 ± 0.035	0.737HisAsn: 0.737 ± 0.038	1.234HisPro: 1.234 ± 0.044	0.64HisGln: 0.64 ± 0.036	1.403HisArg: 1.403 ± 0.06	1.022HisSer: 1.022 ± 0.04	1.301HisThr: 1.301 ± 0.05	1.813HisVal: 1.813 ± 0.054	0.339HisTrp: 0.339 ± 0.025	0.673HisTyr: 0.673 ± 0.038	0.0HisXaa: 0.0 ± 0.0
Ile	7.061IleAla: 7.061 ± 0.115	0.674IleCys: 0.674 ± 0.036	4.074IleAsp: 4.074 ± 0.087	3.233IleGlu: 3.233 ± 0.089	1.57IlePhe: 1.57 ± 0.06	4.732IleGly: 4.732 ± 0.105	0.935IleHis: 0.935 ± 0.038	3.055IleIle: 3.055 ± 0.088	1.83IleLys: 1.83 ± 0.064	3.821IleLeu: 3.821 ± 0.106	1.383IleMet: 1.383 ± 0.054	1.849IleAsn: 1.849 ± 0.051	2.66IlePro: 2.66 ± 0.069	1.377IleGln: 1.377 ± 0.047	2.98IleArg: 2.98 ± 0.08	3.182IleSer: 3.182 ± 0.083	3.509IleThr: 3.509 ± 0.094	4.895IleVal: 4.895 ± 0.098	0.591IleTrp: 0.591 ± 0.032	1.148IleTyr: 1.148 ± 0.044	0.0IleXaa: 0.0 ± 0.0
Lys	4.902LysAla: 4.902 ± 0.105	0.187LysCys: 0.187 ± 0.017	2.542LysAsp: 2.542 ± 0.076	2.227LysGlu: 2.227 ± 0.07	1.078LysPhe: 1.078 ± 0.046	3.031LysGly: 3.031 ± 0.094	1.005LysHis: 1.005 ± 0.04	1.909LysIle: 1.909 ± 0.063	1.997LysLys: 1.997 ± 0.072	3.427LysLeu: 3.427 ± 0.078	0.982LysMet: 0.982 ± 0.045	1.609LysAsn: 1.609 ± 0.06	2.341LysPro: 2.341 ± 0.07	1.759LysGln: 1.759 ± 0.061	2.642LysArg: 2.642 ± 0.074	2.36LysSer: 2.36 ± 0.068	2.66LysThr: 2.66 ± 0.067	2.905LysVal: 2.905 ± 0.079	0.502LysTrp: 0.502 ± 0.034	1.151LysTyr: 1.151 ± 0.055	0.0LysXaa: 0.0 ± 0.0
Leu	10.022LeuAla: 10.022 ± 0.182	1.052LeuCys: 1.052 ± 0.047	5.803LeuAsp: 5.803 ± 0.102	4.403LeuGlu: 4.403 ± 0.093	3.141LeuPhe: 3.141 ± 0.086	6.952LeuGly: 6.952 ± 0.12	1.91LeuHis: 1.91 ± 0.055	4.703LeuIle: 4.703 ± 0.123	3.565LeuLys: 3.565 ± 0.094	7.827LeuLeu: 7.827 ± 0.153	2.234LeuMet: 2.234 ± 0.062	3.182LeuAsn: 3.182 ± 0.064	4.35LeuPro: 4.35 ± 0.089	2.631LeuGln: 2.631 ± 0.061	4.994LeuArg: 4.994 ± 0.109	5.397LeuSer: 5.397 ± 0.11	5.304LeuThr: 5.304 ± 0.088	6.368LeuVal: 6.368 ± 0.126	0.988LeuTrp: 0.988 ± 0.045	1.997LeuTyr: 1.997 ± 0.06	0.0LeuXaa: 0.0 ± 0.0
Met	3.09MetAla: 3.09 ± 0.078	0.278MetCys: 0.278 ± 0.024	1.488MetAsp: 1.488 ± 0.05	1.17MetGlu: 1.17 ± 0.045	0.957MetPhe: 0.957 ± 0.043	1.997MetGly: 1.997 ± 0.062	0.611MetHis: 0.611 ± 0.029	1.386MetIle: 1.386 ± 0.051	1.015MetLys: 1.015 ± 0.043	2.838MetLeu: 2.838 ± 0.074	0.86MetMet: 0.86 ± 0.038	1.03MetAsn: 1.03 ± 0.045	1.699MetPro: 1.699 ± 0.054	0.955MetGln: 0.955 ± 0.037	1.934MetArg: 1.934 ± 0.06	1.827MetSer: 1.827 ± 0.054	1.943MetThr: 1.943 ± 0.057	2.026MetVal: 2.026 ± 0.06	0.296MetTrp: 0.296 ± 0.025	0.61MetTyr: 0.61 ± 0.034	0.0MetXaa: 0.0 ± 0.0
Asn	4.185AsnAla: 4.185 ± 0.081	0.274AsnCys: 0.274 ± 0.023	2.113AsnAsp: 2.113 ± 0.068	2.019AsnGlu: 2.019 ± 0.068	0.908AsnPhe: 0.908 ± 0.049	3.657AsnGly: 3.657 ± 0.09	0.703AsnHis: 0.703 ± 0.035	1.789AsnIle: 1.789 ± 0.056	1.468AsnLys: 1.468 ± 0.048	2.654AsnLeu: 2.654 ± 0.059	0.919AsnMet: 0.919 ± 0.044	1.241AsnAsn: 1.241 ± 0.049	2.128AsnPro: 2.128 ± 0.066	1.095AsnGln: 1.095 ± 0.05	1.995AsnArg: 1.995 ± 0.055	1.791AsnSer: 1.791 ± 0.07	2.21AsnThr: 2.21 ± 0.066	2.634AsnVal: 2.634 ± 0.067	0.463AsnTrp: 0.463 ± 0.029	0.89AsnTyr: 0.89 ± 0.043	0.0AsnXaa: 0.0 ± 0.0
Pro	4.648ProAla: 4.648 ± 0.116	0.368ProCys: 0.368 ± 0.031	3.029ProAsp: 3.029 ± 0.084	3.203ProGlu: 3.203 ± 0.087	1.675ProPhe: 1.675 ± 0.056	3.341ProGly: 3.341 ± 0.087	0.948ProHis: 0.948 ± 0.039	2.246ProIle: 2.246 ± 0.058	1.832ProLys: 1.832 ± 0.065	3.63ProLeu: 3.63 ± 0.076	1.188ProMet: 1.188 ± 0.046	1.675ProAsn: 1.675 ± 0.057	1.231ProPro: 1.231 ± 0.049	1.871ProGln: 1.871 ± 0.065	2.086ProArg: 2.086 ± 0.061	2.859ProSer: 2.859 ± 0.077	2.675ProThr: 2.675 ± 0.072	3.787ProVal: 3.787 ± 0.085	0.673ProTrp: 0.673 ± 0.037	1.347ProTyr: 1.347 ± 0.049	0.0ProXaa: 0.0 ± 0.0
Gln	4.01GlnAla: 4.01 ± 0.097	0.318GlnCys: 0.318 ± 0.022	1.624GlnAsp: 1.624 ± 0.055	1.682GlnGlu: 1.682 ± 0.051	1.068GlnPhe: 1.068 ± 0.043	2.482GlnGly: 2.482 ± 0.067	0.85GlnHis: 0.85 ± 0.041	1.975GlnIle: 1.975 ± 0.056	1.153GlnLys: 1.153 ± 0.046	3.296GlnLeu: 3.296 ± 0.096	0.993GlnMet: 0.993 ± 0.037	1.219GlnAsn: 1.219 ± 0.057	1.663GlnPro: 1.663 ± 0.067	1.703GlnGln: 1.703 ± 0.062	2.329GlnArg: 2.329 ± 0.071	2.259GlnSer: 2.259 ± 0.073	2.013GlnThr: 2.013 ± 0.062	2.494GlnVal: 2.494 ± 0.077	0.606GlnTrp: 0.606 ± 0.028	1.214GlnTyr: 1.214 ± 0.053	0.0GlnXaa: 0.0 ± 0.0
Arg	4.929ArgAla: 4.929 ± 0.118	0.55ArgCys: 0.55 ± 0.033	3.218ArgAsp: 3.218 ± 0.082	3.69ArgGlu: 3.69 ± 0.09	2.287ArgPhe: 2.287 ± 0.061	3.727ArgGly: 3.727 ± 0.092	1.546ArgHis: 1.546 ± 0.053	3.819ArgIle: 3.819 ± 0.088	2.665ArgLys: 2.665 ± 0.074	5.237ArgLeu: 5.237 ± 0.113	2.024ArgMet: 2.024 ± 0.053	2.249ArgAsn: 2.249 ± 0.067	2.236ArgPro: 2.236 ± 0.073	2.258ArgGln: 2.258 ± 0.069	4.265ArgArg: 4.265 ± 0.131	3.293ArgSer: 3.293 ± 0.077	3.29ArgThr: 3.29 ± 0.082	4.025ArgVal: 4.025 ± 0.094	0.775ArgTrp: 0.775 ± 0.039	1.936ArgTyr: 1.936 ± 0.058	0.0ArgXaa: 0.0 ± 0.0
Ser	6.301SerAla: 6.301 ± 0.105	0.562SerCys: 0.562 ± 0.033	3.88SerAsp: 3.88 ± 0.093	3.17SerGlu: 3.17 ± 0.064	2.167SerPhe: 2.167 ± 0.07	5.583SerGly: 5.583 ± 0.111	1.309SerHis: 1.309 ± 0.051	3.441SerIle: 3.441 ± 0.082	2.392SerLys: 2.392 ± 0.07	5.288SerLeu: 5.288 ± 0.109	1.808SerMet: 1.808 ± 0.053	2.188SerAsn: 2.188 ± 0.072	2.37SerPro: 2.37 ± 0.061	2.19SerGln: 2.19 ± 0.07	3.329SerArg: 3.329 ± 0.083	4.098SerSer: 4.098 ± 0.107	3.761SerThr: 3.761 ± 0.104	4.597SerVal: 4.597 ± 0.106	0.816SerTrp: 0.816 ± 0.037	1.759SerTyr: 1.759 ± 0.055	0.0SerXaa: 0.0 ± 0.0
Thr	6.354ThrAla: 6.354 ± 0.132	0.553ThrCys: 0.553 ± 0.031	3.707ThrAsp: 3.707 ± 0.08	2.828ThrGlu: 2.828 ± 0.082	2.164ThrPhe: 2.164 ± 0.071	5.246ThrGly: 5.246 ± 0.109	1.19ThrHis: 1.19 ± 0.046	3.526ThrIle: 3.526 ± 0.079	2.184ThrLys: 2.184 ± 0.057	5.537ThrLeu: 5.537 ± 0.109	1.597ThrMet: 1.597 ± 0.047	2.016ThrAsn: 2.016 ± 0.059	3.146ThrPro: 3.146 ± 0.078	1.973ThrGln: 1.973 ± 0.063	2.985ThrArg: 2.985 ± 0.074	3.402ThrSer: 3.402 ± 0.081	3.846ThrThr: 3.846 ± 0.106	5.554ThrVal: 5.554 ± 0.121	0.77ThrTrp: 0.77 ± 0.04	1.66ThrTyr: 1.66 ± 0.062	0.0ThrXaa: 0.0 ± 0.0
Val	8.316ValAla: 8.316 ± 0.146	0.989ValCys: 0.989 ± 0.042	4.953ValAsp: 4.953 ± 0.109	4.362ValGlu: 4.362 ± 0.088	2.896ValPhe: 2.896 ± 0.074	5.411ValGly: 5.411 ± 0.099	1.566ValHis: 1.566 ± 0.055	4.308ValIle: 4.308 ± 0.093	3.099ValLys: 3.099 ± 0.08	7.156ValLeu: 7.156 ± 0.139	2.048ValMet: 2.048 ± 0.06	2.717ValAsn: 2.717 ± 0.073	3.736ValPro: 3.736 ± 0.076	2.287ValGln: 2.287 ± 0.064	4.403ValArg: 4.403 ± 0.094	5.219ValSer: 5.219 ± 0.098	4.732ValThr: 4.732 ± 0.106	6.688ValVal: 6.688 ± 0.144	0.969ValTrp: 0.969 ± 0.041	1.902ValTyr: 1.902 ± 0.064	0.0ValXaa: 0.0 ± 0.0
Trp	1.17TrpAla: 1.17 ± 0.052	0.148TrpCys: 0.148 ± 0.016	0.797TrpAsp: 0.797 ± 0.039	0.565TrpGlu: 0.565 ± 0.029	0.506TrpPhe: 0.506 ± 0.03	0.952TrpGly: 0.952 ± 0.046	0.397TrpHis: 0.397 ± 0.028	0.698TrpIle: 0.698 ± 0.041	0.642TrpLys: 0.642 ± 0.03	1.417TrpLeu: 1.417 ± 0.048	0.421TrpMet: 0.421 ± 0.027	0.615TrpAsn: 0.615 ± 0.038	0.509TrpPro: 0.509 ± 0.03	0.613TrpGln: 0.613 ± 0.031	0.921TrpArg: 0.921 ± 0.045	0.812TrpSer: 0.812 ± 0.033	0.747TrpThr: 0.747 ± 0.036	0.889TrpVal: 0.889 ± 0.044	0.269TrpTrp: 0.269 ± 0.022	0.473TrpTyr: 0.473 ± 0.034	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.083TyrAla: 3.083 ± 0.081	0.332TyrCys: 0.332 ± 0.023	1.893TyrAsp: 1.893 ± 0.069	1.602TyrGlu: 1.602 ± 0.056	0.993TyrPhe: 0.993 ± 0.044	2.702TyrGly: 2.702 ± 0.071	0.562TyrHis: 0.562 ± 0.032	1.173TyrIle: 1.173 ± 0.046	0.964TyrLys: 0.964 ± 0.047	2.321TyrLeu: 2.321 ± 0.071	0.65TyrMet: 0.65 ± 0.032	0.862TyrAsn: 0.862 ± 0.037	1.204TyrPro: 1.204 ± 0.049	0.95TyrGln: 0.95 ± 0.048	1.757TyrArg: 1.757 ± 0.062	1.653TyrSer: 1.653 ± 0.054	1.597TyrThr: 1.597 ± 0.06	2.123TyrVal: 2.123 ± 0.056	0.448TyrTrp: 0.448 ± 0.029	0.856TyrTyr: 0.856 ± 0.048	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 1724 proteins (587324 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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